CN109171643A - A kind of MX-P neuron resuscitation therapy children's Neurological disease technology - Google Patents

A kind of MX-P neuron resuscitation therapy children's Neurological disease technology Download PDF

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Publication number
CN109171643A
CN109171643A CN201810647706.5A CN201810647706A CN109171643A CN 109171643 A CN109171643 A CN 109171643A CN 201810647706 A CN201810647706 A CN 201810647706A CN 109171643 A CN109171643 A CN 109171643A
Authority
CN
China
Prior art keywords
neuron
detector
neurotransmitter
neurological disease
children
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810647706.5A
Other languages
Chinese (zh)
Inventor
洪磊
杨炳如
张淞
毕士祥
项全富
李军
孟斌
王立文
朱彦丽
梁月竹
范肖冬
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenyang Shenbei Medical Hospital
Nanjing Renkang Hospital Co Ltd
Original Assignee
Shenyang Shenbei Medical Hospital
Nanjing Renkang Hospital Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenyang Shenbei Medical Hospital, Nanjing Renkang Hospital Co Ltd filed Critical Shenyang Shenbei Medical Hospital
Priority to CN201810647706.5A priority Critical patent/CN109171643A/en
Publication of CN109171643A publication Critical patent/CN109171643A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064Evaluating the brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition

Abstract

The invention discloses a kind of MX-P neuron resuscitation therapy children's Neurological disease technologies, including pedestal, cabinet and fixed frame, the inside of cabinet is from left to right successively arranged neurotransmitter detector and micro-electrophoresis apparatus, one end of connecting rod is equipped with shield, the inside of shield is equipped with detector, and the top of detector is fixedly connected by electric telescopic rod with the bottom end of connecting rod, the inside of protective housing is equipped with glass microelectrode and inert electrode, the top of fixing seat is equipped with external controlling terminal, the side of external controlling terminal is equipped with display screen, a kind of MX-P neuron resuscitation therapy children's Neurological disease technology of the present invention, neurotransmitter detector is controlled by external controlling terminal to position the neuron that children are damaged, and the big neurotransmitter of brain nine is stimulated by control micro-electrophoresis apparatus, get through signal transmission path, reach reparation Neuron adjusts the long-term unbalance purpose of neurotransmitter, and establishes record tracks.

Description

A kind of MX-P neuron resuscitation therapy children's Neurological disease technology
Technical field
The present invention relates to children's internal disease, in particular to a kind of MX-P neuron resuscitation therapy children's Neurological disease Technology belongs to field of medical technology.
Background technique
It is known that the nervous system of the mankind is great and complicated, to this organ group that will affect children's brain development The research knitted perplexs always scientific circles for many years, and children mostly dynamic, twitch, enruesis etc. are even more that medical field is allowed to be stymied by.Until 1987, foreign scholar the study found that human brain nine big neurotransmitter disorders, be only really influence children's cranial nerve development Arch-criminal.Children's brain is also more complicated than adult, because it is also in growth phase, nerve cell has choosing in growth course Selecting property is eliminated, but with child grows, brain development gradually shapes, and intervention will be increasingly difficult to, and simple drug is can not Repair and activate from the root downright bad nerve cell.For children's brain, disease type is segmented, sufficiently carries out and examines preceding assessment body It is tied to form as children cognition disorder disease specification diagnosis and treatment standard requirements, the big neurotransmitter of the nine of children's brain is to directly control children's mind The root of mediator transmitting balance through cell.Therefore, " MX-P neuron recovery therapy " is determined impaired by dot matrix location technology Neuron, reuse electro physiology Ventral medulla method stimulation the big neurotransmitter of brain nine, get through signal transmission path.
Summary of the invention
The purpose of the present invention is to provide a kind of MX-P neuron resuscitation therapy children's Neurological disease technologies, to solve Existing simple drug mentioned above in the background art is can not to repair and activate from the root asking for downright bad nerve cell Topic.
To achieve the above object, the invention provides the following technical scheme: a kind of MX-P neuron resuscitation therapy children are neural Internal disease technology, including pedestal, cabinet and fixed frame, the two sides of described pedestal one end are equipped with idler wheel, and the pedestal is another End is equipped with universal wheel, and the side on the top of the pedestal is equipped with cabinet, and the inside of the cabinet is from left to right successively arranged nerve The top of mediator detector and micro-electrophoresis apparatus, the cabinet is fixedly connected by several springs with the bottom end of fixed frame, described solid The side for determining frame top is equipped with bed board, and one end of the bed board is rotatablely connected by one end of the second shaft and sole, the bed The other end of plate is rotatablely connected by one end of first rotating shaft and backup plate, and the side at the top of the fixed frame is equipped with connecting rod, described One end of connecting rod is equipped with shield, and the inside of the shield is equipped with detector, and the top of the detector is stretched by electronic Contracting bar is fixedly connected with the bottom end of connecting rod, and the side of the fixed frame is equipped with cross bar, and the top of the cross bar is equipped with protective housing, institute The inside for stating protective housing is equipped with glass microelectrode and inert electrode, the other side fixing seat on the pedestal top, the fixing seat Inside be equipped with medicine-chest, the top of the fixing seat is equipped with external controlling terminal, and the side of the external controlling terminal is equipped with aobvious Display screen.
As a preferred technical solution of the present invention, the side of the pedestal, which is equipped with, to be ridden, and the foot-operated top is set There is non-slip mat.
As a preferred technical solution of the present invention, the side of the fixed frame is equipped with side plate, the top of the side plate Offer article putting groove.
As a preferred technical solution of the present invention, the detector and neurotransmitter detector are electrically connected, described Glass microelectrode and micro-electrophoresis apparatus are electrically connected, the neurotransmitter detector, display screen and micro-electrophoresis apparatus with external control Terminal is electrically connected.
As a preferred technical solution of the present invention, the neurotransmitter detector, micro-electrophoresis apparatus, external control are eventually End, display screen and electric telescopic rod are electrically connected with external power supply.
Compared with prior art, the beneficial effects of the present invention are: a kind of MX-P neuron resuscitation therapy children mind of the present invention Through internal disease technology, neurotransmitter detector is controlled by external controlling terminal, the neuron that children are damaged is positioned, And the big neurotransmitter of brain nine is stimulated by control micro-electrophoresis apparatus, signal transmission path is got through, repair of neuron is reached, adjusts mind Through the long-term unbalance purpose of mediator, and establish record tracks.
Detailed description of the invention
Fig. 1 is positive structure schematic of the present invention;
Fig. 2 is the structural schematic diagram of work flow diagram of the invention;
Fig. 3 is the structural schematic diagram of side plate of the invention;
Fig. 4 is foot-operated structural schematic diagram of the invention.
In figure: 1, backup plate;2, connecting rod;3, shield;4, electric telescopic rod;5, detector;6, universal wheel;7, first turn Axis;8, neurotransmitter detector;9, idler wheel;10, pedestal;11, cabinet;12, fixed frame;13, the second shaft;14, sole;15, Bed board;16, micro-electrophoresis apparatus;17, side plate;18, it rides;19, display screen;20, external controlling terminal;21, fixing seat;22, medicine-chest; 23, protective housing;24, glass microelectrode;25, inert electrode.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Fig. 1-4 is please referred to, the present invention provides a kind of MX-P neuron resuscitation therapy children's Neurological disease technology, packets Pedestal 10, cabinet 11 and fixed frame 12 are included, the two sides of 10 one end of pedestal are equipped with idler wheel 9, and 10 other end of pedestal is equipped with universal wheel 6, the side on the top of pedestal 10 is equipped with cabinet 11, and the inside of cabinet 11 is from left to right successively arranged 8 He of neurotransmitter detector The top of micro-electrophoresis apparatus 16, cabinet 11 is fixedly connected by several springs with the bottom end of fixed frame 12, and the one of 12 top of fixed frame Side is equipped with bed board 15, and one end of bed board 15 is rotatablely connected by the second shaft 13 and one end of sole 14, the other end of bed board 15 It is rotatablely connected by one end of first rotating shaft 7 and backup plate 1, the side at 12 top of fixed frame is equipped with connecting rod 2, and one end of connecting rod 2 is set There is shield 3, the inside of shield 3 is equipped with detector 5, and the top of detector 5 passes through the bottom of electric telescopic rod 4 and connecting rod 2 End is fixedly connected, and the side of fixed frame 12 is equipped with cross bar, and the top of cross bar is equipped with protective housing 23, and the inside of protective housing 23 is equipped with glass The inside of glass microelectrode 24 and inert electrode 25, the other side fixing seat 21 on 10 top of pedestal, fixing seat 21 is equipped with medicine-chest 22, Gu The top of reservation 21 is equipped with external controlling terminal 20, and the side of external controlling terminal 20 is equipped with display screen 19.
Preferably, the side of pedestal 10 is equipped with foot-operated 18, and the top for riding 18 is equipped with non-slip mat, and foot-operated 18 lie convenient for people On bed board 15.
Preferably, the side of fixed frame 12 is equipped with side plate 17, and the top of side plate 17 offers article putting groove, and article putting groove places one A little toys can hold toy, ease off the pressure during children therapy.
Preferably, detector 5 and neurotransmitter detector 8 are electrically connected, and glass microelectrode 24 and micro-electrophoresis apparatus 16 are electrically Connection, neurotransmitter detector 8, display screen 19 and micro-electrophoresis apparatus 16 are electrically connected with external controlling terminal 20, the micro- electricity of glass Pharmaceutical aqueous solution electrophoresis is entered tissue and cell by pole 24.
Preferably, neurotransmitter detector 8, micro-electrophoresis apparatus 16, external controlling terminal 20, display screen 19 and electric telescopic rod 4 are electrically connected with external power supply, and the display of display screen 19 is examined by external controlling terminal 20 treated neurotransmitter detector 8 The result of survey.
When specifically used, a kind of MX-P neuron resuscitation therapy children's Neurological disease technology of the present invention, patient is lain in On bed board 15, the angle of backup plate 1 is rotated by first rotating shaft 7, promotes the comfort of people, while electric telescopic rod 4 drives inspection Gauge head 5 starts neurotransmitter detector 8 and external controlling terminal 20, detector 5 is to the impaired of patient close to the brain of patient Neural position is positioned, and is fed back and handled to external controlling terminal 20, and is shown by display screen 19, at this point, Start micro-electrophoresis apparatus 16, and takes out glass microelectrode 24 and inert electrode 25 from protective housing 23, and take out in medicine-chest 22 simultaneously Therapeutic agent, is intended to that electrophoresis enters tissue and the pharmaceutical aqueous solution of cell pours into glass microelectrode 24, will be electric using inert electrode 25 Stream introduces glass microelectrode 24, adjusts size of current and type by external controlling terminal 20, stimulates the big neurotransmitter of brain nine, Signal transmission path is got through, synaptic cleft is allowed to act on the specific receptor of postsynaptic membrane, plays its physiological action, by mediator ion It is applied to impaired neuron, and then inducing ion channel opener, to generate chemical substance that is excited or inhibiting, reaches reparation Neuron adjusts the long-term unbalance purpose of neurotransmitter, and therapeutic effect is fed back to external controlling terminal 20 simultaneously, establishes disease Example archives, subsequent progress follow-up observation treatment.
In the description of the present invention, it is to be understood that, term " coaxial ", " bottom ", " one end ", " top ", " middle part ", The orientation or positional relationship of the instructions such as " other end ", "upper", " side ", " top ", "inner", " front ", " center ", " both ends " is It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair Limitation of the invention.
In addition, term " first ", " second ", " third ", " the 4th " are used for description purposes only, and should not be understood as instruction or It implies relative importance or implicitly indicates the quantity of indicated technical characteristic, define " first ", " second ", " the as a result, Three ", the feature of " the 4th " can explicitly or implicitly include at least one of the features.
In the present invention unless specifically defined or limited otherwise, term " installation ", " setting ", " connection ", " fixation ", Terms such as " being screwed on " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral;It can be with It is mechanical connection, is also possible to be electrically connected;It can be directly connected, two can also be can be indirectly connected through an intermediary The interaction relationship of connection or two elements inside a element, unless otherwise restricted clearly, for the common of this field For technical staff, the specific meanings of the above terms in the present invention can be understood according to specific conditions.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (5)

1. a kind of MX-P neuron resuscitation therapy children's Neurological disease technology, including pedestal (10), cabinet (11) and fixation Frame (12), which is characterized in that the two sides of described pedestal (10) one end are equipped with idler wheel (9), and pedestal (10) other end is equipped with Universal wheel (6), the side on the top of the pedestal (10) are equipped with cabinet (11), and the inside of the cabinet (11) is from left to right successively Equipped with neurotransmitter detector (8) and micro-electrophoresis apparatus (16), the top of the cabinet (11) passes through several springs and fixed frame (12) bottom end is fixedly connected, and the side on fixed frame (12) top is equipped with bed board (15), and one end of the bed board (15) is logical The one end for crossing the second shaft (13) and sole (14) is rotatablely connected, the other end of the bed board (15) by first rotating shaft (7) with One end of backup plate (1) is rotatablely connected, and the side at the top of the fixed frame (12) is equipped with connecting rod (2), and one end of the connecting rod (2) is set Have shield (3), the inside of the shield (3) is equipped with detector (5), and the top of the detector (5) is stretched by electronic Contracting bar (4) is fixedly connected with the bottom end of connecting rod (2), and the side of the fixed frame (12) is equipped with cross bar, and the top of the cross bar is set Have protective housing (23), the inside of the protective housing (23) is equipped with glass microelectrode (24) and inert electrode (25), the pedestal (10) inside of the other side fixing seat (21) on top, the fixing seat (21) is equipped with medicine-chest (22), the fixing seat (21) Top is equipped with external controlling terminal (20), and the side of the external controlling terminal (20) is equipped with display screen (19).
2. a kind of MX-P neuron resuscitation therapy children's Neurological disease technology according to claim 1, feature exist In: the side of the pedestal (10) is equipped with foot-operated (18), and the top of foot-operated (18) is equipped with non-slip mat.
3. a kind of MX-P neuron resuscitation therapy children's Neurological disease technology according to claim 1, feature exist In: the side of the fixed frame (12) is equipped with side plate (17), and the top of the side plate (17) offers article putting groove.
4. a kind of MX-P neuron resuscitation therapy children's Neurological disease technology according to claim 1, feature exist In: the detector (5) and neurotransmitter detector (8) are electrically connected, the glass microelectrode (24) and micro-electrophoresis apparatus (16) It is electrically connected, the neurotransmitter detector (8), display screen (19) and micro-electrophoresis apparatus (16) are electric with external controlling terminal (20) Property connection.
5. a kind of MX-P neuron resuscitation therapy children's Neurological disease technology according to claim 1, feature exist In: the neurotransmitter detector (8), micro-electrophoresis apparatus (16), external controlling terminal (20), display screen (19) and electric telescopic rod (4) it is electrically connected with external power supply.
CN201810647706.5A 2018-06-17 2018-06-17 A kind of MX-P neuron resuscitation therapy children's Neurological disease technology Pending CN109171643A (en)

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Application Number Priority Date Filing Date Title
CN201810647706.5A CN109171643A (en) 2018-06-17 2018-06-17 A kind of MX-P neuron resuscitation therapy children's Neurological disease technology

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Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030032001A1 (en) * 2001-04-06 2003-02-13 Broderick Patricia A. Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using microelectrodes with microvoltammetry
CN101011618A (en) * 2006-09-18 2007-08-08 郭国祯 Electromagnetic impulse irradiation system and method for promoting medicament to permeate bloodbrain barrier
CN102210905A (en) * 2010-04-02 2011-10-12 鼎迈医疗科技(苏州)有限公司 Implanted nerve electrical stimulation system with drug release device
CN102335065A (en) * 2011-07-28 2012-02-01 重庆大学 Implanted retina micro-stimulation electrode chip with drug slow release function
CN102793973A (en) * 2012-08-03 2012-11-28 中国科学院深圳先进技术研究院 Device for treating Parkinson's disease
CN103977501A (en) * 2014-05-26 2014-08-13 沈锐 MX brain balance rehabilitation system, established by using multiple instruments in combination, for treating various cranial nerve system diseases
CN104546360A (en) * 2015-01-10 2015-04-29 管勇 Nerve detection treatment bed
CN204581528U (en) * 2015-04-21 2015-08-26 吴国红 Children's's Neurology Department diagnostic bed
CN205568956U (en) * 2016-03-31 2016-09-14 师林 Brain neurotransmitter detector
CN108143432A (en) * 2017-12-27 2018-06-12 刘伟泉 A kind of Neuroloqical inspectoscope

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030032001A1 (en) * 2001-04-06 2003-02-13 Broderick Patricia A. Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using microelectrodes with microvoltammetry
CN101011618A (en) * 2006-09-18 2007-08-08 郭国祯 Electromagnetic impulse irradiation system and method for promoting medicament to permeate bloodbrain barrier
CN102210905A (en) * 2010-04-02 2011-10-12 鼎迈医疗科技(苏州)有限公司 Implanted nerve electrical stimulation system with drug release device
CN102335065A (en) * 2011-07-28 2012-02-01 重庆大学 Implanted retina micro-stimulation electrode chip with drug slow release function
CN102793973A (en) * 2012-08-03 2012-11-28 中国科学院深圳先进技术研究院 Device for treating Parkinson's disease
CN103977501A (en) * 2014-05-26 2014-08-13 沈锐 MX brain balance rehabilitation system, established by using multiple instruments in combination, for treating various cranial nerve system diseases
CN104546360A (en) * 2015-01-10 2015-04-29 管勇 Nerve detection treatment bed
CN204581528U (en) * 2015-04-21 2015-08-26 吴国红 Children's's Neurology Department diagnostic bed
CN205568956U (en) * 2016-03-31 2016-09-14 师林 Brain neurotransmitter detector
CN108143432A (en) * 2017-12-27 2018-06-12 刘伟泉 A kind of Neuroloqical inspectoscope

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Application publication date: 20190111