CN1091667A - Platinum-plated electrotherapeutic electrode for inserting into body and its plating process - Google Patents
Platinum-plated electrotherapeutic electrode for inserting into body and its plating process Download PDFInfo
- Publication number
- CN1091667A CN1091667A CN 93101973 CN93101973A CN1091667A CN 1091667 A CN1091667 A CN 1091667A CN 93101973 CN93101973 CN 93101973 CN 93101973 A CN93101973 A CN 93101973A CN 1091667 A CN1091667 A CN 1091667A
- Authority
- CN
- China
- Prior art keywords
- platinum
- electrode
- tinsel
- metal
- technology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000007747 plating Methods 0.000 title claims abstract description 15
- 238000000034 method Methods 0.000 title description 11
- 230000008569 process Effects 0.000 title description 6
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims abstract description 56
- 229910052697 platinum Inorganic materials 0.000 claims abstract description 27
- 229910052751 metal Inorganic materials 0.000 claims abstract description 23
- 239000002184 metal Substances 0.000 claims abstract description 23
- 238000005516 engineering process Methods 0.000 claims abstract description 13
- 150000003058 platinum compounds Chemical class 0.000 claims abstract description 10
- 229940045985 antineoplastic platinum compound Drugs 0.000 claims description 9
- 238000001827 electrotherapy Methods 0.000 claims description 8
- 230000001476 alcoholic effect Effects 0.000 claims description 7
- 239000002253 acid Substances 0.000 claims description 6
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims description 5
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 claims description 5
- 229910052721 tungsten Inorganic materials 0.000 claims description 5
- 239000010937 tungsten Substances 0.000 claims description 5
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 4
- 229910052750 molybdenum Inorganic materials 0.000 claims description 4
- 239000011733 molybdenum Substances 0.000 claims description 4
- FBEIPJNQGITEBL-UHFFFAOYSA-J tetrachloroplatinum Chemical compound Cl[Pt](Cl)(Cl)Cl FBEIPJNQGITEBL-UHFFFAOYSA-J 0.000 claims description 4
- 229910052737 gold Inorganic materials 0.000 claims description 3
- 239000010931 gold Substances 0.000 claims description 3
- 229910052759 nickel Inorganic materials 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 4
- 206010011409 Cross infection Diseases 0.000 abstract description 3
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 3
- 230000007246 mechanism Effects 0.000 abstract description 2
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 238000004381 surface treatment Methods 0.000 abstract 1
- 230000008901 benefit Effects 0.000 description 5
- 238000002560 therapeutic procedure Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 230000007797 corrosion Effects 0.000 description 3
- 238000005260 corrosion Methods 0.000 description 3
- 230000005611 electricity Effects 0.000 description 3
- 150000002739 metals Chemical class 0.000 description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 208000035269 cancer or benign tumor Diseases 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000003487 electrochemical reaction Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 208000033781 Thyroid carcinoma Diseases 0.000 description 1
- 208000024770 Thyroid neoplasm Diseases 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000007646 directional migration Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 230000005518 electrochemistry Effects 0.000 description 1
- 201000005619 esophageal carcinoma Diseases 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000001050 pharmacotherapy Methods 0.000 description 1
- CLSUSRZJUQMOHH-UHFFFAOYSA-L platinum dichloride Chemical compound Cl[Pt]Cl CLSUSRZJUQMOHH-UHFFFAOYSA-L 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000010970 precious metal Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 201000008261 skin carcinoma Diseases 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 201000002510 thyroid cancer Diseases 0.000 description 1
- 208000013077 thyroid gland carcinoma Diseases 0.000 description 1
- 230000002476 tumorcidal effect Effects 0.000 description 1
- 238000001771 vacuum deposition Methods 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Landscapes
- Electrotherapy Devices (AREA)
Abstract
The electrotherapeutic electrode for treating tumor is inserted into body and has the mechanism of treating tumor by means of electrochemical effect and features that platinum-plated metal needle is used to replace pure platinum needle, resulting in low cost and no cross infection. The technological measure of the technology is that metal wires with the melting point higher than 400 ℃ are coated with alcohol solution of platinum compound after surface treatment, and then the platinum plating layer is formed after baking. The performance of the electrode with the structure is not inferior to that of a pure platinum electrode.
Description
The present invention relates to a kind of treat tumor the insertion body in the platinum plating electrotherapy electrode used itself and process for plating, the acusector that its architectural feature is made up of platinized tinsel; Technology characteristics is to adopt the alcoholic solution of platinum compounds, be coated on the tinsel, through high-temperature baking, platinum compounds is decomposed after, form the coating of platinum.
The method of the electrochemical treatment of malignant tumour that Sweden's strong nurse of physician Ou Dengsi is started successfully is applied to clinical treatment in China, obtains tangible curative effect, and this technology has been passed through the ministerial level technical appraisement.This method is called as electricity doctor's amic therapy method, and electricity doctor amic therapy method treatment malignant tumor is compared with X-ray therapy, pharmacotherapy and heating therapy, has easy and simple to handle, short treating period, instant effect and the painless advantage of waiting bitterly for of patient.
Electricity doctor amic therapy method is according to matter closed circuit theory between vascular, adopts the tumoricidal conditions of existence of electrochemical effect, thereby suppresses its growth, causes neoplasm necrosis, reaches the purpose of treatment tumor.Its treatment mechanism and technical characterstic are: with two metal fine needles, be punctured to tumor center and contiguous position thereof exactly, connect low voltage direct current then on two pins, like this, form positive polar region and negative pole district near two acusectors respectively.A series of electrochemical reaction and electrophysiologic response take place thereupon, and under electric field action, the material in the body tissue, ion and water all can directional migrations, form a kind of new distribution.Positive polar region is acid, and the negative pole district is an alkalescence.Chlorine and oxygen that electrochemical reaction produces have extremely strong oxidisability, and the migration of water causes tissue dewatering or edema, and these variations make cancerous cell lose the condition of existence, cause neoplasm necrosis.And organizing of peripheral cell is injury-free basically.
According to the electrochemical metal order, the metal more than hydrogen: potassium, sodium, magnesium, ferrum, stannum and aluminum in aqueous solution, perhaps in human body, can form hydrated metal ion and dissolve.Therefore, if do electrode with these metals, current potential shakiness then, electrode is easily broken, can not be used for the treatment of.The metal of electrochemistry order below hydrogen: copper, silver, gold and platinum, if do electrode, because 0.95% body fluid is sodium chloride in the body with the metal except that platinum, chloride ion loses electronics, these metals produce chlorine, and these metals can not stand corrosion again, so more should not be made electrode.Thereby can only adopt platinum to make electrode, platinum is a precious metal, costs an arm and a leg.
The strong nurse of Ou Dengsi adopts spiral electrode, its objective is at less platinum electrode to obtain than large tracts of land, reduces the consumption of platinum.The diameter of its platinum filament has only 0.02mm.But this spiral electrode can only use once.Bigger shortcoming is that the bubble of separating out is big, and electric current density is big, the discharge voltage height, so material diffusional interchange speed is restricted, and the broken needle phenomenon takes place easily.
The patent No. be 89207791.3 Chinese patent in order to overcome the shortcoming of above-mentioned spiral electrode, a kind of electrode of straight shape structure is disclosed, the diameter of platinum pin is 0.3～1.0mm.Therefore the electrode cost is very high, must take to be repeatedly used and reduce medical expense.Being repeatedly used is the advantage of this technology, also is the shortcoming of this technology, and medical device repeats repeatedly to use in the body because very abstain from the current clinical medicine to enter, in case cross infection.
The objective of the invention is to avoid above-mentioned the deficiencies in the prior art, and adopt the architectural feature of gold,platinized on tinsel, make the price of electrotherapy electrode become cheap, and improve hardness, the operation in the more convenient treatment.Its process for plating is inventor grope out in practical studies a kind of very easy and extremely practical has certain Promethean technology, make this technology on the electrotherapy acusector of treatment tumor, obtain fabulous application, for this application, electroplate with the metal process for plating of vacuum coating and so on and seem that shape is seen clumsy, not too practical mutually.
The present invention adopts the tinsel of common metal (non-valuable) to achieve these goals, is coated with platinum on its surface, makes the platinum plating metal needle, metal needle be shaped as straight shape, perhaps spiral type.Its process for plating feature comprises: the tinsel of selecting for use molten point to be higher than 400 ℃, pass through clean, and be coated with alcoholic solution with platinum compounds on its surface, through high-temperature baking, make the platinum compounds decomposition and, become the platinum plating tinsel firm being plated on the tinsel of platinum.
Accompanying drawing 1 is the sketch map of the platinum plating metal needle of treatment tumor.Wherein 1 is tinsel, and 2 is platinum coating, and 3 is body.
Embodiment:
1, with platinum tetrachloride (Ptcl
4) be dissolved in the ethanol, concentration is 1～2g/10ml, platinum tetrachloride is suitable with chemical pure.Tungsten filament is handled through cleaning surfaces, and the platinum tetrachloride alcoholic solution is coated on the tungsten filament surface, and baking is decomposed platinum chloride and platinum is plated on the tungsten filament under 400～600 ℃ high temperature.
2, with chloroplatinic acid (H
2Ptcl
66H
2O) be dissolved in the ethanol, concentration 1～2g/10ml, chloroplatinic acid is suitable with chemical pure, and molybdenum filament is handled through cleaning surfaces, and the chloroplatinic acid alcoholic solution is coated on the surface of molybdenum wire under, and baking is decomposed chloroplatinic acid and platinum is plated on the molybdenum filament under 500～600 ℃ of high temperature.
Through the electrotherapy electrode of above-mentioned technical finesse, have good corrosion resistance, in normal saline, applying 700 coulomb electric charge rear surfaces does not have corrosion and does not have and come off.This electrotherapy electrode is compared with existing electrode and is had the following advantages:
1, has hard straight and upright, not flexible, advantage such as frangibility not with tungsten, molybdenum, the platinized acusector of nickel metal and pure platinum acusector.
2, the cost of platinum plating metal electrode and pure platinum electrode can reduce by 10 times, so therefore the decline that price can be bigger can be avoided reusing, prevents cross infection.
Platinum plating technology of the present invention is used to insert the electrotherapy electrode of using in the body, very appropriate benefit.
Electrode of the present invention is equally applicable to treat pulmonary carcinoma, skin carcinoma, breast carcinoma, hepatocarcinoma and thyroid carcinoma.Recent a kind of electrode for the treatment of esophageal carcinoma of releasing, the also electrode of suitable feature structure of the present invention.
Claims (10)
1, a kind of electrotherapy electrode of using in the body that inserts is made up of platinum wire, it is characterized in that described platinum wire is a kind of platinized metal needle.
2, electrode according to claim 1 is characterized in that described platinum plating metal needle, the metal that adopts molten point to be higher than 400 ℃.
3, electrode according to claim 1 and 2 is characterized in that described metal is a tungsten, perhaps molybdenum or nickel.
4, electrode according to claim 1 and 2 is characterized in that described metal needle is straight shape or spiral.
5, electrode according to claim 3 is characterized in that described metal needle is straight shape or spiral.
6, a kind of on tinsel the technology of gold,platinized, comprise tinsel and platinum compounds solution, it is characterized in that described tinsel requirement is selected for use is higher than 400 ℃ tinsel, and described platinum compounds solution is alcoholic solution, and the tinsel that is coated with the platinum compounds alcoholic solution must at high temperature toast.
7, technology according to claim 6 is characterized in that described platinum compounds is platinum tetrachloride (ptcl
4) or chloroplatinic acid (H
2Ptcl
66H
2O).
8, according to claim 5 or 6 described technologies, the concentration that it is characterized in that described platinum compounds alcoholic solution is 1～2g/10ml.
9,, it is characterized in that described baking high temperature is 400～600 ℃ according to claim 5 or 6 described technologies.
10, technology according to claim 7 is characterized in that described baking high temperature is 400～600 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93101973 CN1091667A (en) | 1993-02-27 | 1993-02-27 | Platinum-plated electrotherapeutic electrode for inserting into body and its plating process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93101973 CN1091667A (en) | 1993-02-27 | 1993-02-27 | Platinum-plated electrotherapeutic electrode for inserting into body and its plating process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1091667A true CN1091667A (en) | 1994-09-07 |
Family
ID=4983885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93101973 Pending CN1091667A (en) | 1993-02-27 | 1993-02-27 | Platinum-plated electrotherapeutic electrode for inserting into body and its plating process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1091667A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100421743C (en) * | 2004-07-07 | 2008-10-01 | 中国原子能科学研究院 | Radioactive electrotherapeutic electrode for treating tumor |
-
1993
- 1993-02-27 CN CN 93101973 patent/CN1091667A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100421743C (en) * | 2004-07-07 | 2008-10-01 | 中国原子能科学研究院 | Radioactive electrotherapeutic electrode for treating tumor |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US1653819A (en) | Electrotherapeutical apparatus | |
| CA1173114A (en) | Body implantable lead with improved dcd electrode | |
| Grundfest et al. | Stainless steel micro‐needle electrodes made by electrolytic pointing | |
| JPH05503454A (en) | Apparatus and method for iontophoretic transport | |
| JPS63102768A (en) | Novel plaster structure for iontophoresis | |
| JP2008529711A (en) | Medical needle with antibacterial and painless function | |
| CN106139388B (en) | Nerve electrode | |
| HUANG et al. | Complete atrioventricular block after arsenic trioxide treatment in an acute promyelocytic leukemic patient | |
| CN108572208B (en) | Flexible stretchable glucose sensor and preparation method and application thereof | |
| KR100877598B1 (en) | Living body electricity needle | |
| CN1091667A (en) | Platinum-plated electrotherapeutic electrode for inserting into body and its plating process | |
| CN104055598A (en) | Implantable-type flexible neural microelectrode of fish biological robot and preparation method thereof | |
| Sato | Differing luminal potential difference of cystic fibrosis and control sweat secretory coils in vitro | |
| CN2057590U (en) | Galvanism electrode for inserting in body | |
| CN109431788A (en) | A kind of galvanic corrosion acupuncture needle | |
| CN209137753U (en) | A kind of intracorporal electrode plate of implantable mouse | |
| CN109793594A (en) | Can spontaneous electro photoluminescence block structure conduction nerve trachea and preparation method thereof | |
| CA1173115A (en) | Body implantable lead | |
| CN207861966U (en) | A kind of charcoal hydrogen water electrode | |
| KR20190047436A (en) | Core-shell nanowire, method of forming the core-shell nanowire, and stretchable composites comprising the core-shell nanowire | |
| CN211024794U (en) | Artificial cochlea electrode | |
| CN2449749Y (en) | Electrotherapy electrode for electrochemical therapeutic instrument | |
| CN1026067C (en) | Electrode for electrochemical therapy of esophageal cancer | |
| KR20120010532A (en) | Acupunctural needle for using micro electrical current | |
| CN204563308U (en) | Physical and chemical reaction DC treatment pastes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Applicant after: China Institute of Atomic Energy Applicant before: Li Zhongzhen |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: LI ZHONGZHEN TO: CHINA ATOMIC ENERGY SCIENCE ACADEMY |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |