CN109157589A - A kind of external-applied ointment and preparation method for Patients with Blood Stasis Syndrome - Google Patents
A kind of external-applied ointment and preparation method for Patients with Blood Stasis Syndrome Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The external-applied ointment and preparation method thereof that the invention discloses a kind of for Patients with Blood Stasis Syndrome, the raw material including following parts by weight: 70 parts of radix paeoniae rubra, 30 parts of Radix Angelicae Sinensis, 15 parts of excrementum pteropi, 10 parts of cattail pollen and 16 parts of licorice.Although the raw material of external-applied ointment of the invention is all common Chinese medicinal material, but scientific compatibility through the invention, according to the principle of tcm treatment according to syndrome differentiation, is prepared for the cause of disease science of hemostasis constitution patient, various types of blood stasis can be treated, cure rate is high, it is used cooperatively by physical therapies such as cupping, moxa-moxibustion, massage and scrapings, not only increases the assimilation effect of drug effect, play booster action, but also the defect of this kind of physical therapy is compensated for, clinical practice proof can get extraordinary therapeutic effect.
Description
Technical field
The present invention relates to the medication field of syndrome of blood stasis, in particular to a kind of external-applied ointment for Patients with Blood Stasis Syndrome.
Background technique
All blood for leaving passages through which vital energy circulates cannot be discharged and dissipate in time, and stay in vivo or blood operation it is unsmooth, the stasis of blood product in
Referred to as hemostasis within passages through which vital energy circulates or internal organs organ.The disease as caused by blood-stasis internal-depression, referred to as syndrome of blood stasis, cause blood stasis
The reason of have cold obstruction causing qi stagnation deficiency of vital energy wound.
The clinical manifestation of syndrome of blood stasis is that ambition is felt oppressed pain, draws shoulder back bitterly, and can follow the heart channel of Hand-Shaoyin to left upper extremity
Radiation, mouth, lip, onyx are livid purple, dimly red tongue, or have petechia, ecchymosis, the symptoms such as uneven pulse or knot, generation.Syndrome of blood stasis mainly has following
Type: 1. blood-stasis internal-depression: its discrimination main points is pareordia shouting pain, even colic pain is difficult to endure, tongue color is purple dark or has petechia, the stasis of blood
Spot, thready and hesitant pulse or knot generation.Stop gathering 2. phlegm is turbid: the people of fat abundant expectoration is common, and for pain based on bored pain, companion sees sleepy, the tongue fur of body weight
It is white greasy, the symptom of the turbid interior Sheng of phlegm such as heavy cunning of pulse condition.3. phlegm stagnancy: pain feature is sudden severe pain, obtains warm pain and subtracts, with chilly
Limb cold, pale tongue with white fur, slow and sunken pulse or it is heavy tight equal tremble with fear as.4. depression and stagnation of QI: often related with emotional factors, pain is mostly distending pain,
Tongue nature is light red or dim red, and tongue fur is thin white, veins string.The above phlegm, the stasis of blood, cold, Yu Yike and folder are shown in altogether.Patients with Blood Stasis Syndrome clinic can be shown as
Shouting pain, fixed pain, tenderness, train of thought hemostasis, ecchymosis, disease product, purplish tongue have ecchymosis, petechia, and She Mai slightly opens, arteries and veins
Puckery, acrotism or deep wiry pulse, string are slow.The multifactor body deficiency of vital energy of the disease is added with overstrain troubled thoughts, causes visceral-qi imbalance, and the motive is not filled, qi and blood fortune
Row is unsmooth, and stasis is formed at the stasis of blood, impatency heart arteries and veins；Or the thermophilic rich fatty diet of factor, delicious food is eaten well, causes to accumulate in phlegm wet, sering is obstructed, blood
Stagnant to invade at the stasis of blood, or by cold-evil people, qi and blood stagnation etc. causes above all diseases.
The drug for treating syndrome of blood stasis currently on the market is more, but curative effect is not very significantly, and therapeutic effect is unobvious, at present
There are some physical therapy methods to assist in the treatment of this kind of illness, but treatment cycle is long, slow effect, the present invention develops a kind of needle
To the externally applied ointment of such Patients with Blood Stasis Syndrome, cooperation is walked tank, massage, moxa-moxibustion and scraping, is treated to the ill, helps very such sufferer
Greatly, cure rate greatly improves.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of external-applied ointment for Patients with Blood Stasis Syndrome,
Dedicated for being directed to shouting pain, fixed pain, tenderness, train of thought hemostasis, ecchymosis, disease product, purplish tongue or having ecchymosis, petechia,
The external-applied ointment that various types of Patients with Blood Stasis Syndrome such as She Mai slightly opens, and uneven pulse, acrotism or deep wiry pulse, string are slow are treated, thoroughly
Skin absorbs fastly, quick, and cure rate is high, and preparation process is also simple, and tank, massage, moxa-moxibustion and scraping are walked in cooperation cooperation, applies to the ill
It controls, the absorption of the efficacy of a drug faster more evenly can be made, moreover it is possible to significantly improve therapeutic effect.
The purpose of the present invention is achieved through the following technical solutions:
A kind of external-applied ointment for Patients with Blood Stasis Syndrome, the raw material including following parts by weight:
70~90 parts of radix paeoniae rubra
30~50 parts of Radix Angelicae Sinensis
15~25 parts of excrementum pteropi
10~20 parts of cattail pollen
16~26 parts of licorice.
Further, a kind of external-applied ointment for Patients with Blood Stasis Syndrome can also include the raw material of following parts by weight:
80 parts of radix paeoniae rubra
40 parts of Radix Angelicae Sinensis
20 parts of excrementum pteropi
20 parts of cattail pollen
20 parts of licorice.
Further, a kind of external-applied ointment for Patients with Blood Stasis Syndrome can also include the raw material of following parts by weight:
90 parts of radix paeoniae rubra
50 parts of Radix Angelicae Sinensis
25 parts of excrementum pteropi
20 parts of cattail pollen
26 parts of licorice.
Further, a kind of external-applied ointment for Patients with Blood Stasis Syndrome can also include the raw material of following parts by weight:
70 parts of radix paeoniae rubra
30 parts of Radix Angelicae Sinensis
15 parts of excrementum pteropi
10 parts of cattail pollen
16 parts of licorice.
The preparation method of the above-mentioned external-applied ointment for Patients with Blood Stasis Syndrome, including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio and remove impurity,
Radix paeoniae rubra, Radix Angelicae Sinensis and licorice are cleaned with pure water, dried spare；
S2, frying: taking the radix paeoniae rubra dried, Radix Angelicae Sinensis, licorice and excrementum pteropi, cattail pollen mixing, mixture is put into 180~
It is fried 4~6 minutes in 250ml vegetable oil, the temperature of the vegetable oil is 80~90 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and it is all that 400~500ml is added in the absolute oil
Intellectual circle is stirred under heating 2~4 minutes and obtains liquid ointment；
S4, cooling packing: naturally cooling to 45~50 DEG C for the liquid ointment, extracts the packing of liquid ointment with syringe
Into container, sealed to the solidification of liquid ointment.
It is the pharmacological property of each raw material of traditional Chinese medicine powder of the invention below:
Radix paeoniae rubra: alias mountain Chinese herbaceous peony or careless Chinese herbaceous peony, property acid hold back that yin is soft, with yin-nourishing, the row stasis of blood, analgesic, cool blood, detumescence function
Effect, the stagnant menostasis of the major function stasis of blood, the accumulation of hernia lump in the abdomen, abdominal pain, hypochondriac pain, bleeding from five sense organs or subcutaneous tissue, bloody flux, discharging fresh blood stool, hot eyes, carbuncle swells, injury from falling down.
Radix Angelicae Sinensis: Radix Angelicae Sinensis is warm-natured, sweet in flavor, pungent；Returns spleen, the heart, Liver Channel；Major function is enriched blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize cunning
Intestines.The main all cards of the deficiency of blood；Irregular menstruation；Menostasis；Dysmenorrhea；Disorder lump in the abdomen knot is poly-；Metrorrhagia and metrostaxis；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness；Intestinal dryness is just
It is difficult；Weight after dysentery with bloody stool；Ulcer sores；Injury from falling down is suitable for deficiency of blood intestinal dryness.It is suitble to the crowd of blood stasis and deficiency-cold in spleen and stomach edible, when
Returning not only plays the role of activating microcirculation and removing stasis medicinal, can be with warming and activating meridian, analgesia spasmolysis, all deficient cold type abdominal pain, traumatic injury, rheumatism numbness
It is logical etc. to use the treatment that ought come back.
Excrementum pteropi: smell sweet, warm, it is nontoxic.Evil person's ginseng, speaks sarcastically.Trusted subordinate's cold air is cured mainly, five infantile malnutrition due to digestive disturbances or intestinalparasites of children wards off epidemic disease, controls intestines wind,
Tonneau gaseous pulse, woman's blood close.It cures the wound cold accumulation (Su Song).All excessive persons of metrorrhagia, half fries half a lifetime as end, and wine clothes can promoting circulation of blood hemostasis；
Control all pains of pricking caused by the stagnation of QI and blood very abdomen, colic, bloody flux intestines wind abdominal pain, body blood-arthralgia shouting pain, liver malaria has a fever, and gastric disorder causing nausea is quenched one's thirst and sputum
Blood is held under the arm into nest, blood passes through pupil, and blood clotting dentalgia, double tongue, child convulsion, the insane disease of five epilepsys, desinsection, solves poisoning of drug and snake, scorpion, centipede hurt.
There is the effect of removing toxic substances, invigorating the spleen disperse accumulation, promoting blood circulation and hemostasis, removing blood stasis and acesodyne.
Cattail pollen: it is mild-natured, it is sweet in flavor.Return liver warp, the heart channel of Hang-Shaoyin；Have effects that hemostasis, Huayu Tonglin, expansion blood vessel.
Licorice: nature and flavor sweet and neutral；Return heart, lung, spleen, stomach meridian.It cures mainly and invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency
Analgesic, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle swells
Sore alleviates drug toxicity, strong.
The application method of externally applied ointment of the invention is: moxibustion position, the stasis of blood are embrocated before row warming needle moxibustion, sandwiched moxibustion, direct contact moxibustion
Blood constitution patient can also be using externally applied ointment of the invention as massage, scraping, the medium for walking tank.
The beneficial effects of the present invention are:
1) externally applied ointment application method of the invention is applied widely, uses the warm needle of row after embrocating physical feeling massage uniformly
Moxibustion, sandwiched moxibustion, direct contact moxibustion, massage, scraping and walk tank suit the medicine to the illness treat, assist in the treatment of hemostasis constitution patient, Transdermal absorption is fast, treat
It imitates, preparation process is also simple, can make the absorption of the efficacy of a drug faster more evenly, can significantly improve therapeutic effect.
Although 2) raw material of external-applied ointment of the invention is all common Chinese medicinal material, scientific compatibility through the invention,
According to the principle of tcm treatment according to syndrome differentiation, is prepared for the cause of disease science of hemostasis constitution patient, various types of blood stasis can be treated, controlled
More rate is high, by moxa-moxibustion, massage, scraping and walks the physical therapies such as tank and is used cooperatively, not only increases the assimilation effect of drug effect, play auxiliary
Effect is helped, but also compensates for the defect of this kind of physical therapy, clinical practice proof can get extraordinary therapeutic effect.
Specific embodiment
Below in conjunction with embodiment, technical solution of the present invention is clearly and completely described, it is clear that described
Embodiment is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field
Technical staff's every other embodiment obtained under the premise of not making the creative labor belongs to what the present invention protected
Range.
The present invention the following technical schemes are provided:
Embodiment 1
A kind of external-applied ointment for Patients with Blood Stasis Syndrome, the raw material including following parts by weight:
80 parts of radix paeoniae rubra
40 parts of Radix Angelicae Sinensis
20 parts of excrementum pteropi
20 parts of cattail pollen
20 parts of licorice.
The preparation method of the external-applied ointment for Patients with Blood Stasis Syndrome, including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio and remove impurity,
Radix paeoniae rubra, Radix Angelicae Sinensis and licorice are cleaned with pure water, dried spare；
S2, frying: the radix paeoniae rubra dried, Radix Angelicae Sinensis, licorice and excrementum pteropi, cattail pollen mixing are taken, mixture is put into 200ml and is planted
Deep fry for five minutes is decocted in object oil, the temperature of the vegetable oil is 85 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and 400 vaseline are added in the absolute oil, then
Obtain liquid ointment within heating stirring 3 minutes；
S4, cooling packing: naturally cooling to 50 DEG C for the liquid ointment, extracts liquid ointment with syringe and dispenses to appearance
In device, sealed to the solidification of liquid ointment.
Embodiment 2
A kind of external-applied ointment for Patients with Blood Stasis Syndrome, the raw material including following parts by weight:
90 parts of radix paeoniae rubra
50 parts of Radix Angelicae Sinensis
25 parts of excrementum pteropi
20 parts of cattail pollen
26 parts of licorice.
The preparation method of the external-applied ointment for Patients with Blood Stasis Syndrome, including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio and remove impurity,
Radix paeoniae rubra, Radix Angelicae Sinensis and licorice are cleaned with pure water, dried spare；
S2, frying: the radix paeoniae rubra dried, Radix Angelicae Sinensis, licorice and excrementum pteropi, cattail pollen mixing are taken, mixture is put into 180ml and is planted
It is fried 4 minutes in object oil, the temperature of the vegetable oil is 80 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and 400ml vaseline is added in the absolute oil,
It is stirred under heating 2 minutes and obtains liquid ointment；
S4, cooling packing: naturally cooling to 45 DEG C for the liquid ointment, extracts liquid ointment with syringe and dispenses to appearance
In device, sealed to the solidification of liquid ointment.
Embodiment 3
A kind of external-applied ointment for Patients with Blood Stasis Syndrome, the raw material including following parts by weight:
70 parts of radix paeoniae rubra
30 parts of Radix Angelicae Sinensis
15 parts of excrementum pteropi
10 parts of cattail pollen
16 parts of licorice.
The preparation method of the external-applied ointment for Patients with Blood Stasis Syndrome, including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio and remove impurity,
Radix paeoniae rubra, Radix Angelicae Sinensis and licorice are cleaned with pure water, dried spare；
S2, frying: the radix paeoniae rubra dried, Radix Angelicae Sinensis, licorice and excrementum pteropi, cattail pollen mixing are taken, mixture is put into 250ml and is planted
It is fried 6 minutes in object oil, the temperature of the vegetable oil is 90 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and 500ml vaseline is added in the absolute oil,
It is stirred under heating 4 minutes and obtains liquid ointment；
S4, cooling packing: naturally cooling to 50 DEG C for the liquid ointment, extracts liquid ointment with syringe and dispenses to appearance
In device, sealed to the solidification of liquid ointment.
Embodiment 4
A kind of external-applied ointment for Patients with Blood Stasis Syndrome, the raw material including following parts by weight:
85 parts of radix paeoniae rubra
45 parts of Radix Angelicae Sinensis
26 parts of excrementum pteropi
18 parts of cattail pollen
22 parts of licorice.
The preparation method of the external-applied ointment for Patients with Blood Stasis Syndrome, including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio and remove impurity,
Radix paeoniae rubra, Radix Angelicae Sinensis and licorice are cleaned with pure water, dried spare；
S2, frying: the radix paeoniae rubra dried, Radix Angelicae Sinensis, licorice and excrementum pteropi, cattail pollen mixing are taken, mixture is put into 220ml and is planted
It is fried 4.5 minutes in object oil, the temperature of the vegetable oil is 86 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and 460ml vaseline is added in the absolute oil,
It is stirred under heating 2.5 minutes and obtains liquid ointment；
S4, cooling packing: naturally cooling to 48 DEG C for the liquid ointment, extracts liquid ointment with syringe and dispenses to appearance
In device, sealed to the solidification of liquid ointment.
Embodiment 5
A kind of external-applied ointment for Patients with Blood Stasis Syndrome, the raw material including following parts by weight:
88 parts of radix paeoniae rubra
46 parts of Radix Angelicae Sinensis
22 parts of excrementum pteropi
18 parts of cattail pollen
21 parts of licorice.
The preparation method of the external-applied ointment for Patients with Blood Stasis Syndrome, including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio and remove impurity,
Radix paeoniae rubra, Radix Angelicae Sinensis and licorice are cleaned with pure water, dried spare；
S2, frying: the good excrementum pteropi of the radix paeoniae rubra, Radix Angelicae Sinensis, licorice dried, cattail pollen mixing are taken, mixture is put into 200ml and is planted
It is fried 5.5 minutes in object oil, the temperature of the vegetable oil is 87 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and 480ml vaseline is added in the absolute oil,
It is stirred under heating 3.6 minutes and obtains liquid ointment；
S4, cooling packing: naturally cooling to 49 DEG C for the liquid ointment, extracts liquid ointment with syringe and dispenses to appearance
In device, sealed to the solidification of liquid ointment.
In above-mentioned 5 embodiments, 50ml medical syringe is can be used in the syringe, and the container can be with glass capsulation
Tank or plastic seal tank, other containers for being used to seal Sheng ointment are suitable for.
The application method of externally applied ointment of the invention is: moxibustion position, the stasis of blood are embrocated before row warming needle moxibustion, sandwiched moxibustion, direct contact moxibustion
Blood constitution patient can also be using externally applied ointment of the invention as massage, scraping, the medium for walking tank.
The clinical practice observations of external-applied ointment of the present invention:
1. clinical case:
It selects in January, 2017 to the outpatient service of in August, 2018 to meet 144 patients of blood stasis symptom diagnostic criteria, is randomly divided into 2
Group: treatment group 72, control group 72；Wherein male to female ratio each 50%, 2 groups of patient ages, gender, the course of disease and card shape weight journey
Through statistical analysis, no significant difference (P > 0.05) is comparable degree etc..
2. diagnostic criteria:
" guideline of clinical investigations of new Chinese medicine treatment syndrome of blood stasis " promulgated referring to the Ministry of Public Health:
Primary symptom: shouting pain, fixed pain, tenderness, train of thought hemostasis, (such as lip, gums, onyx are purple dark, the red thread of skin table, or
Abdomen has blue veins exposed), ecchymosis, disease product, blood circulating out of vessels purplish tongue or has ecchymosis, petechia, and She Mai slightly opens, uneven pulse, nothing
Arteries and veins or deep wiry pulse, string are slow.
Minor symptom: scaly dry skin, a symptom of blood stasis, extremity numbness or hemiplegia are crazy about insane, and mad ` is hot-tempered, forgetful, localized paresthesia, trauma history, operation
History and history of artificial abortion.
Have the above primary symptom 2 or 1, minor symptom 2, i.e., diagnosable syndrome of blood stasis.
3. exclusion criteria:
(1) standard of being included in is not met, there is obvious and folder card or merges card person；
(2) age is at under-18s 75 years old or more, gestation or breast feeding women, allergic constitution and those who are allergic to this drug；
(3) the severe primaries disease such as angiocarpy, the cerebrovascular, liver, kidney, hemopoietic system, mental patient are associated with；
(4) unconsciousness, subjective malaise symptoms cannot be expressed, with serious depression and anxiety symptom or mental disease person；
(5) progressivity malignant tumour or other serious deelines, easy concurrent infection and bleeder；Merging angiocarpy,
The primary diseases persons such as liver, kidney, digestion, hemopoietic system:
(6) ray of teratogenesis amount, poisonous substance, drug were contacted and is in action period or there are the bad habits such as excessive drinking, drug abuse；
(7) compliance is poor, refusal participates in testing or be reluctant to sign informed consent form and follow-up is difficult, can not judge curative effect,
Or data is not congruent affects the treatment or safety judgement person.
4. treatment method:
External-applied ointment governor vessel that treatment group is prepared using the embodiment of the present invention 1, bladder meridian 1,2 side lines walk tank, treat within every 3 days
Once, 6 times it is as a treatment course, treat 3 courses for the treatment of；Vaseline governor vessel, bladder meridian 1,2 side lines of control group routine walk tank.
5. curative effect determinate standard:
(1) cure: clinical symptoms, the sign disappear or mostly disappear of blood stasis, disease integration reduce >=95%；
(2) effective: clinical symptoms, the sign of blood stasis are obviously improved, and disease integration reduces >=70%；
(3) effectively: clinical symptoms, the sign of blood stasis take a favorable turn, and disease integration reduces >=30%；
(4) invalid: without improvement, disease integration is reduced less than 30% for the clinical symptoms of blood stasis, sign.
Calculation formula (Nimodipine method) are as follows: ((pre-treatment score-post treatment integral)/pre-treatment score) × 100%.
6. treatment results:
The different group efficacy result statistics of table 1
Clinical recovery 23 in 72 patients for the treatment of group, cure rate 32%；Effective 17, obvious effective rate 23.6%；Effective 19
Example, effective percentage 26.34%；Total effective rate reaches 81.94.%.
Clinical recovery 9 in 72 patients of control group, cure rate 12.5%；Effective 13, obvious effective rate 18.05%；Effectively
22, effective percentage 30.55%；Total effective rate is up to 61.11%.
By result above as can be seen that external-applied ointment of the invention is by walking the cooperation of tank, compared to not having to medicine of the present invention
Object is treated, and total effective rate is higher by 20.83%, illustrates that ointment Transdermal absorption of the invention is fast, good effect, while its preparation process
Simply, tank is walked in cooperation, is treated to the ill, can be made the absorption of the efficacy of a drug faster more evenly, can significantly improve therapeutic effect, cure rate reaches
80% or more.
The above is only a preferred embodiment of the present invention, it should be understood that the present invention is not limited to described herein
Form should not be regarded as an exclusion of other examples, and can be used for other combinations, modifications, and environments, and can be at this
In the text contemplated scope, modifications can be made through the above teachings or related fields of technology or knowledge.And those skilled in the art institute into
Capable modifications and changes do not depart from the spirit and scope of the present invention, then all should be in the protection scope of appended claims of the present invention
It is interior.
Claims (5)
1. a kind of external-applied ointment for Patients with Blood Stasis Syndrome, which is characterized in that the raw material including following parts by weight:
70~90 parts of radix paeoniae rubra
30~50 parts of Radix Angelicae Sinensis
15~25 parts of excrementum pteropi
10~20 parts of cattail pollen
16~26 parts of licorice.
2. the external-applied ointment according to claim 1 for Patients with Blood Stasis Syndrome, which is characterized in that including following parts by weight
Raw material:
80 parts of radix paeoniae rubra
40 parts of Radix Angelicae Sinensis
20 parts of excrementum pteropi
20 parts of cattail pollen
20 parts of licorice.
3. the external-applied ointment according to claim 1 for Patients with Blood Stasis Syndrome, which is characterized in that including following parts by weight
Raw material:
90 parts of radix paeoniae rubra
50 parts of Radix Angelicae Sinensis
25 parts of excrementum pteropi
20 parts of cattail pollen
26 parts of licorice.
4. the external-applied ointment according to claim 1 for Patients with Blood Stasis Syndrome, which is characterized in that including following parts by weight
Raw material:
70 parts of radix paeoniae rubra
30 parts of Radix Angelicae Sinensis
15 parts of excrementum pteropi
10 parts of cattail pollen
16 parts of licorice.
5. the preparation method of the external-applied ointment according to any one of claims 1-4 for Patients with Blood Stasis Syndrome, which is characterized in that
Including the following steps:
S1, it weighs drug: weighing radix paeoniae rubra, Radix Angelicae Sinensis, excrementum pteropi, cattail pollen and licorice respectively according to the above ratio, remove impurity, it will be red
Chinese herbaceous peony, Radix Angelicae Sinensis and licorice are cleaned with pure water, are dried spare；
S2, frying: the radix paeoniae rubra dried, Radix Angelicae Sinensis, licorice and excrementum pteropi, cattail pollen mixing are taken, mixture is put into 180~250ml
It is fried 4~6 minutes in vegetable oil, the temperature of the vegetable oil is 80~90 DEG C；
S3, dregs of a decoction filtering: the dregs of a decoction in filtration step S2 filter out absolute oil, and 400~500ml vaseline is added in the absolute oil,
It is stirred under heating 2~4 minutes and obtains liquid ointment；
S4, cooling packing: naturally cooling to 45~50 DEG C for the liquid ointment, extracts liquid ointment with syringe and dispenses to appearance
In device, sealed to the solidification of liquid ointment.
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Citations (2)
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|---|---|---|---|---|
| CN101940720A (en) * | 2010-09-10 | 2011-01-12 | 重庆市南川区金佛山中药材品种培育研究所 | Traditional Chinese herbal medicine for treating peptic ulcer (blood stasis obstructing the collaterals) |
| CN105521175A (en) * | 2016-01-20 | 2016-04-27 | 黄庆辉 | Traditional Chinese medicine for treating blood stasis type hypomenorrhea |
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2018
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| CN101940720A (en) * | 2010-09-10 | 2011-01-12 | 重庆市南川区金佛山中药材品种培育研究所 | Traditional Chinese herbal medicine for treating peptic ulcer (blood stasis obstructing the collaterals) |
| CN105521175A (en) * | 2016-01-20 | 2016-04-27 | 黄庆辉 | Traditional Chinese medicine for treating blood stasis type hypomenorrhea |
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Application publication date: 20190108 |