CN109157211A - A kind of portable cardiac on-line intelligence monitoring diagnosis system design method - Google Patents

A kind of portable cardiac on-line intelligence monitoring diagnosis system design method Download PDF

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CN109157211A
CN109157211A CN201810921525.7A CN201810921525A CN109157211A CN 109157211 A CN109157211 A CN 109157211A CN 201810921525 A CN201810921525 A CN 201810921525A CN 109157211 A CN109157211 A CN 109157211A
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scatter plot
rdr
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岳大超
刘海宽
张磊
李致远
蒋大伟
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Jiangsu Normal University
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems

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Abstract

The invention discloses a kind of portable cardiac on-line intelligence monitoring diagnosis system design methods.Including being filtered denoising to electrocardiosignal, R crest value position is extracted;RdR scatter plot is drawn using heartbeat interval;RdR scatter plot is zoomed in and out, grayscale image is changed into, image data is normalized;The scatter plot sample of acquisition is marked;Sample is sampled, randomly selects 85% data as training sample;Parameter is set;Approximate base, characteristic value, feature vector are solved to every class sample respectively;The SPE of each test sample is calculated separately, value and the SPE difference reckling of certain class sample calculate accuracy rate compared with concrete class for the prediction classification of test sample;Disaggregated model parameter is obtained, and the disaggregated model of acquisition is used in cardiac diagnosis system.The present invention carries out cardioelectric monitor diagnosis using the method for integrating sparse kernel principle component analysis, has satisfactory diagnosis recognition effect.

Description

A kind of portable cardiac on-line intelligence monitoring diagnosis system design method
Technical field
The present invention relates to a kind of portable cardiac on-line intelligence monitoring diagnosis system design methods, belong to intelligent medical technology Field.
Background technique
Cardiovascular disease is unhealthful important killer, in June, 2017 " Chinese cardiovascular disease report 2016 " publication.Report It points out: currently, cardiovascular death accounts for the first place of the total cause of death of urban and rural residents, and 10 years cardiovascular disease numbers of patients from now on It will rapid growth.In addition, will be about 23,300,000 people according to the report of the World Health Organization to the year two thousand thirty and died of angiocarpy Disease.In face of this trend, the early diagnosis and prevention of cardiovascular disease are particularly important.
Traditional diagnostic method is patient to hospital, and doctor carries out ECG examination to it, and then provides diagnostic result, is appointed It is engaged in heavy and doctor is needed to have clinical experience abundant and professional knowledge;And rare medical resource, it is difficult to meet substantial amounts The requirement of PATIENT POPULATION.In order to improve medical efficiency, convenience and agility, there is automated diagnostic technology, assist doctor It is diagnosed.
Heart rate variability refers to the time-variance number between cardiac cycle, and research object is cardiac cycle rather than heart rate. The heart rate of people be not it is unalterable, there is small time differences between heartbeat twice, calculate the difference of cardiac cycle, It can be appreciated that heart rate variability (Heart rate variability, HRV).
Heart rate variability can assess the influence of cardiac sympathetic nerve and parasympathetic nerve to cardiovascular activity, contain the heart Bulk information in terms of blood vessel.Clinical research shows that the reduction of heart rate variability is the hearts such as myocardial infarction, hypertension, angina pectoris The symptom of vascular morbidity.Therefore, the research of heart rate variability, in evaluation systema cariovasculare functional, prediction cardiovascular disease Breaking-out, and have great importance for the early diagnosis of cardiovascular disease.
Poincare scatter plot is a kind of important research method of heart rate variability: being existed by using continuous heartbeat interval Graphing in rectangular coordinate system reflects the variation of adjacent heartbeat interval, can show the feature of heartbeat interval;Poincare dissipates For point diagram there are many form, including comet formation, sector etc., different shapes reflects different heart states.
Although Poincare scatter plot is a kind of effective heart rate variance analyzing method, it can not be embodied at any time Between the trend that changes, its heart rate variability cannot be embodied well for certain cardiovascular diseases, physical condition etc. Matter.Then, some scholars propose improvement strategy, i.e. first order difference plot, are drawn by the difference of adjacent heartbeat interval Scatter plot.However, this method is lost the absolute value information of original heartbeat interval again;Therefore, and scholar combines the two Get up, propose a kind of RdR scatter plot, come with this while reflecting heartbeat interval and its variation.
Currently, many for the heart rate variability analysis of different cardiovascular diseases;But there is no come from according to scatter plot Different cardiovascular diseases is distinguished in dynamic identification, realizes electrocardio automated diagnostic.
Summary of the invention
In view of the above existing problems in the prior art, the present invention provides a kind of portable cardiac on-line intelligence monitoring, diagnosing systems Unite design method, by integrate sparse kernel principle component analysis method can automatic recognition classification scatter plot, to heart rate variability make Analysis provides to realize automated diagnostic, the waste alleviated medical resource in short supply, reduce medical resource, improving medical efficiency Basis.
To achieve the goals above, the present invention provides a kind of portable cardiac on-line intelligence monitoring diagnosis system design side Method, specific steps are as follows:
Step 1) acquires electrocardiosignal, is filtered denoising to electrocardiosignal, extracts R crest value position;
Step 2) draws electrocardio RdR scatter plot using heartbeat interval;
Step 3) zooms in and out electrocardio RdR scatter plot, zooms to same specification, changes into grayscale image, and to image data It is normalized, to reduce calculation amount;
The scatter plot sample of acquisition is marked in step 4);
Step 5) samples sample, randomly selects 85% data as training sample;
Parameter is arranged in step 6), and parameter includes the value of the error parameter of approximate base, gaussian kernel function parameter and control limit;
Step 7) solves approximate base, characteristic value, feature vector to every class sample respectively;
Step 8) calculates separately the SPE of each test sample, and the SPE difference reckling of value and certain class sample is test specimens This prediction classification calculates accuracy rate compared with concrete class, the step 9) if meeting the requirements, otherwise return step 6) again Parameter training is set;
Step 9) obtains disaggregated model parameter, and the disaggregated model of acquisition is used in cardiac diagnosis system.
Further, using integrating sparse kernel principle component analysis method for the Classification and Identification of the electrocardio RdR scatter plot. RdR scatter plot is a kind of heart rate variance analyzing method, can embody its trend changed over time.
Further, sparse kernel principle component analysis method will be integrated and is used for Classification and Identification to the electrocardio RdR scatter plot, first Foundation integrates sparse kernel principle component analysis model, then selects Con trolling index by square prediction error method.
Integrating sparse kernel principle component analysis is a kind of unsupervised machine learning algorithm, integrates the base of sparse kernel principle component analysis This method is as follows:
Principal component analysis is a kind of typical unsupervised algorithm, is usually used in solving the linear problem of luv space, and in order to The nonlinear problem of luv space is solved with linear method in feature space, B.Scholkopf et al. proposes core principal component It analyzes (Kernel Principal Component Analysis, KPCA).It defines from luv space RnTo feature space F's Nonlinear Mapping:If given sample X={ x1,…,xN},xi∈Rn, then pass throughMapping can obtain one Group vectorAssuming that this group of vector meetsThen the Correlation Matrix in feature space is
If this group of vectorIt can then enableKnown toMeet Condition, instead of in formulaThen KPCA problem, which can be converted to, seeks Correlation Matrix in feature spaceEigenvalue λ, that is, feature Vector
Wherein,It is the linear combination of sample, enablesɑ=[ɑ1,…,ɑN]T, thenWhenWhen cannot explicitly obtaining, kernel function is introduced, ifFirstly the need of calculating:
K=ΦTΦ;
Wherein, matrix K is the matrix of NxN, also referred to as nuclear matrix.Then problem is converted are as follows:
K ɑ=N λ ɑ;
Wherein, ɑ=[ɑ1,…,ɑN].WhenThe process of centralization can the operation directly on K:
Wherein,MeetIt is 1 matrix of a NxN.Assuming that obtaining 1 >=λ of eigenvalue λ 2 >=... λ n and its corresponding feature vector ɑ1,ɑ2,…,ɑN,K-th of feature in feature space to Amountɑi,kIt indicatesK-th of feature vector i-th of value, byIt normalizesK-th of the feature vector of variable x after normalizationDirection is projected as k-th of principal component, Formula are as follows:
The present invention selects a kind of common kernel function, and Radial basis kernel function is calculated.When selection Radial basis kernel function When, apparent overfitting problem is had, mainly since the corresponding feature space of Radial basis kernel function is wirelessly tieed up, is passed through The number for the principal component that this method obtains is unrelated with the dimension of given sample, and related with sample size.It is asked to solve this Topic, introduces rarefaction method, as sparse kernel principle component analysis (Sparse Kernel Principal Component Analysis,SKPCA)。
In kernel principle component analysis, feature vector can use sampleIt is expressed as That is feature vectorIt is the linear combination of whole samples, this provides a kind of thinking for the rarefaction of feature vector.It is logical Approximate base derivation algorithm is crossed, to askApproximate base, to obtainRarefaction method.
What approximate base solved comprises the concrete steps that:
A. set is establishedFor approximate Maximum independent group, XA=φ;
B. for k=2 ..., N'sMinimizing value;
C. if obtaining minimum value≤ε, corresponding element is added to XAIt in the middle, is otherwise Xl.ε is linearly related Truncated error asks the base of infinite dimensional space almost without sparsity in limited sample, therefore selects approximate calculation.
D. return step B, until completing all calculating, calculating terminates.
Wherein, the solution procedure in step B is as follows:
By Lagrange conditionObtain -2K0λ=0+2K, wherein K0=(k (x1,xk),…,k(xl,xk))T, the side of being K Battle array, Kij=k (xi,xj).When kernel function is gaussian radial basis function, matrix K positive definite obtains λmin=K-1K0As f's (λ) Minimum point.
Assuming that the one group of approximation base acquired isWithIndicate approximate base The base vector of composition, feature vector can be expressed asProblem changes into:
Both sides are same to be multipliedNote?
Known to the problem of being eigen vector, i.e.,It enablesThen
It derives:
Wherein, K (m :) indicates the m row of nuclear matrix K, and K (:, n) indicates the n-th column, 1N=[1 ..., 1] indicate 1 row N column Row vector.Problem has also been converted into (KI)-1Ksα=λ α is typical eigen vector problem.
Although rarefaction can control the learning ability of learning machine, overfitting is prevented, rarefaction method still may Certain key properties of data set can be lost, that is, owe problem concerning study.Therefore, it is necessary to introduce integrated approach, referred to as integrate sparse Kernel principle component analysis (Integration Sparse Kernel Principal Component Analysis, ISKPCA).
Since kernel principle component analysis is a kind of unsupervised learning, cannot be instructed from outside, i.e., it cannot be to certain study As a result it is awarded or is punished, so, the method for simple average is selected herein.The integrated approach specific steps process of SKPCA is such as Under:
A., duplicate number Re is set;
B. nuclear matrix K=Φ is calculatedTΦ;
C. sample set is calculatedThe approximate base Φ of Re groupI 1,…,ΦI Re(solving kth group approximation base Φ I kWhen, previous group approximation base ΦI k-1Remaining vector is the prioritized vector of kth group);
D. according to above-mentioned SKPCA method, to each group of approximate base ΦI kSeek eigenvalue λk, feature vector ɑk, obtain altogether Re group eigenvalue λ1,…,λReWith feature vector ɑ1,…,ɑRe
E. to preceding n eigenvalue λ1≥…≥λnWith corresponding feature vector, integration characteristic value is sought respectivelyIntegration characteristic vectorWherein λi kIt is kth group approximation base ΦI kThe subspace opened is I-th acquired the characteristic value of solution space,It is corresponding feature vector;
F. to integration characteristic valueWith integrated feature vectorIt is normalized to get sparse kernel principle component analysis is integrated Characteristic value and feature vector.
The Classification and Identification for sparse kernel principle component analysis method will be integrated being used for electrocardio RdR scatter plot, needs first to establish integrated Sparse kernel principle component analysis model, then selects Con trolling index.The present invention selects a kind of common Con trolling index, i.e., square pre- It surveys error (Squared Prediction Error, SPE).
The specific method of square prediction error:
For i-th of sample Xi, it is assumed that acquiring its preceding n principal component by SKPCA is t1,…,tn, corresponding characteristic value For λ1,…,λn.WithIndicate the reconstruct vector of the N number of principal component of feature spaceSimilarly The then SPE of sample X is defined as:
Wherein,
Compared with prior art, beneficial effects of the present invention are as follows:
The present invention is using sparse kernel principle component analysis method is integrated, by calculating sample data and using kernel principle component analysis Difference between mapping data carrys out the maximum correlation between data, and judges electrocardiogram (ECG) data classification with this, research from Dynamic identification classification RdR scatter plot.Performed an analysis using the method for the present invention to heart rate variability, can for realize automated diagnostic, Alleviate medical resource in short supply, the waste for reducing medical resource, some bases of medical efficiency offer are provided.
Detailed description of the invention
Fig. 1 is specific method flow chart of the present invention;
Fig. 2 is system structure diagram;
Fig. 3 is RdR scatter plot.
Fig. 4 is to randomly choose test sample and all kinds of SPE differences;
Fig. 5 is the partial test result figure with test data testing classification device performance.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts it is all its His embodiment, shall fall within the protection scope of the present invention.
As shown in Figure 1, a kind of portable cardiac on-line intelligence monitoring diagnosis system design method provided by the invention, specifically Step are as follows:
Step 1) acquires electrocardiosignal, is filtered denoising to electrocardiosignal, extracts R crest value position;
Step 2) draws electrocardio RdR scatter plot using heartbeat interval;
Step 3) zooms in and out electrocardio RdR scatter plot, zooms to same specification, changes into grayscale image, and to image data It is normalized, to reduce calculation amount;
The scatter plot sample of acquisition is marked in step 4);
Step 5) samples sample, randomly selects 85% data as training sample;
Parameter is arranged in step 6), and parameter includes the value of the error parameter of approximate base, gaussian kernel function parameter and control limit;
Step 7) solves approximate base, characteristic value, feature vector to every class sample respectively;
Step 8) calculates separately the SPE of each test sample, and the SPE difference reckling of value and certain class sample is test specimens This prediction classification calculates accuracy rate compared with concrete class, the step 9) if meeting the requirements, otherwise return step 6) again Parameter training is set;
Step 9) obtains disaggregated model parameter, and the disaggregated model of acquisition is used in cardiac diagnosis system.
Further, using integrating sparse kernel principle component analysis method for the Classification and Identification of the electrocardio RdR scatter plot. RdR scatter plot is a kind of heart rate variance analyzing method, can embody its trend changed over time.
Further, sparse kernel principle component analysis method will be integrated and is used for Classification and Identification to the electrocardio RdR scatter plot, first Foundation integrates sparse kernel principle component analysis model, then selects Con trolling index by square prediction error method.
Integrating sparse kernel principle component analysis is a kind of unsupervised machine learning algorithm, integrates the base of sparse kernel principle component analysis This method is as follows:
Principal component analysis is a kind of typical unsupervised algorithm, is usually used in solving the linear problem of luv space, and in order to The nonlinear problem of luv space is solved with linear method in feature space, B.Scholkopf et al. proposes core principal component It analyzes (Kernel Principal Component Analysis, KPCA).It defines from luv space RnTo feature space F's Nonlinear Mapping:If given sample X={ x1,…,xN},xi∈Rn, then pass throughMapping can obtain one group VectorAssuming that this group of vector meetsThen the Correlation Matrix in feature space is
If this group of vectorIt can then enableKnown toMeet Condition, instead of in formulaThen KPCA problem, which can be converted to, seeks Correlation Matrix in feature spaceEigenvalue λ, that is, feature Vector
Wherein,It is the linear combination of sample, enablesɑ=[ɑ1,…,ɑN]T, thenWhenWhen cannot explicitly obtaining, kernel function is introduced, ifFirstly the need of calculating:
K=ΦTΦ;
Wherein, matrix K is the matrix of NxN, also referred to as nuclear matrix.Then problem is converted are as follows:
K ɑ=N λ ɑ;
Wherein, ɑ=[ɑ1,…,ɑN].WhenThe process of centralization can the operation directly on K:
Wherein,MeetIt is 1 matrix of a NxN.Assuming that obtaining 1 >=λ of eigenvalue λ 2 >=... λ n and its corresponding feature vector ɑ12,…,ɑN,K-th of feature in feature space to Amountɑi,kIt indicatesK-th of feature vector i-th of value, byIt normalizesK-th of the feature vector of variable x after normalizationDirection is projected as k-th of master point Amount, formula are as follows:
The present invention selects a kind of common kernel function, and Radial basis kernel function is calculated.When selection Radial basis kernel function When, apparent overfitting problem is had, mainly since the corresponding feature space of Radial basis kernel function is wirelessly tieed up, is passed through The number for the principal component that this method obtains is unrelated with the dimension of given sample, and related with sample size.It is asked to solve this Topic, introduces rarefaction method, as sparse kernel principle component analysis (Sparse Kernel Principal Component Analysis,SKPCA)。
In kernel principle component analysis, feature vector can use sampleIt is expressed as? That is feature vectorIt is the linear combination of whole samples, this provides a kind of thinking for the rarefaction of feature vector.Pass through Approximate base derivation algorithm, to askApproximate base, to obtainRarefaction method.
What approximate base solved comprises the concrete steps that:
A. set is establishedFor approximate Maximum independent group, XA=φ;
B. for k=2 ..., N'sMinimizing value;
Wherein,
C. if obtaining minimum value≤ε, corresponding element is added to XAIt in the middle, is otherwise Xl.ε is linearly related Truncated error asks the base of infinite dimensional space almost without sparsity in limited sample, therefore selects approximate calculation.
D. return step B, until completing all calculating, calculating terminates.
Wherein, the solution procedure in step B is as follows:
It enables
By Lagrange conditionObtain -2K0λ=0+2K, wherein K0=(k (x1,xk),…,k(xl,xk))T, the side of being K Battle array, Kij=k (xi,xj).When kernel function is gaussian radial basis function, matrix K positive definite obtains λmin=K-1K0As f's (λ) Minimum point.
Assuming that the one group of approximation base acquired isWithIndicate approximate base The base vector of composition, feature vector can be expressed asProblem changes into:
Both sides are same to be multipliedNote?
Known to the problem of being eigen vector, i.e.,It enablesThen
It derives:
Wherein, K (m :) indicates the m row of nuclear matrix K, and K (:, n) indicates the n-th column, 1N=[1 ..., 1] indicate 1 row N column Row vector.Problem has also been converted into (KI)-1Ksα=λ α is typical eigen vector problem.
Although rarefaction can control the learning ability of learning machine, overfitting is prevented, rarefaction method still may Certain key properties of data set can be lost, that is, owe problem concerning study.Therefore, it is necessary to introduce integrated approach, referred to as integrate sparse Kernel principle component analysis (Integration Sparse Kernel Principal Component Analysis, ISKPCA).
Since kernel principle component analysis is a kind of unsupervised learning, cannot be instructed from outside, i.e., it cannot be to certain study As a result it is awarded or is punished, so, the method for simple average is selected herein.The integrated approach specific steps process of SKPCA is such as Under:
A., duplicate number Re is set;
B. nuclear matrix K=Φ is calculatedTΦ;
C. sample set is calculatedThe approximate base Φ of Re groupI 1,…,ΦI Re(solving kth group approximation base Φ I kWhen, previous group approximation base ΦI k-1Remaining vector is the prioritized vector of kth group);
D. according to above-mentioned SKPCA method, to each group of approximate base ΦI kSeek eigenvalue λk, feature vector ɑk, obtain altogether Re group eigenvalue λ1,…,λReWith feature vector ɑ1,…,ɑRe
E. to preceding n eigenvalue λ1≥…≥λnWith corresponding feature vector, integration characteristic value is sought respectivelyIntegration characteristic vectorWherein λi kIt is kth group approximation base ΦI kThe subspace opened is I-th acquired the characteristic value of solution space,It is corresponding feature vector;
F. to integration characteristic valueWith integrated feature vectorIt is normalized to get sparse kernel principle component analysis is integrated Characteristic value and feature vector.
The Classification and Identification for sparse kernel principle component analysis method will be integrated being used for electrocardio RdR scatter plot, needs first to establish integrated Sparse kernel principle component analysis model, then selects Con trolling index.The present invention selects a kind of common Con trolling index, i.e., square pre- It surveys error (Squared Prediction Error, SPE).
The specific method of square prediction error:
For i-th of sample Xi, it is assumed that acquiring its preceding n principal component by SKPCA is t1,…,tn, corresponding characteristic value For λ1,…,λn.WithIndicate the reconstruct vector of the N number of principal component of feature spaceSimilarly The then SPE of sample X is defined as:
Wherein,
Using the electrocardiogram (ECG) data in MIT-BIH database, to make schematically analysis with the data of this database convenient for narration It introduces.
Fig. 2 is system structure diagram, the hardware of the system mainly by Acquisition Circuit, microcontroller circuit, storage circuit, RAM circuit, jtag circuit, telecommunication circuit, circuit for alarming, LED operation indicating circuit, electric power management circuit and Cloud Server etc. Composition.In order to reduce the complexity of system, this system selects B/S (browser/server) mode in remote monitoring terminal part To develop.This system connects into an entirety by internet, and to meet portable feature, is designed using single lead.Acquisition Circuit is responsible for acquiring electrocardiosignal, carries out data filtering on the microprocessor, then the information such as LCD display waveform, heart rate, can Data are uploaded to Cloud Server using telecommunication circuit, received server-side to data handles data, and obtains Diagnostic analysis report, according to diagnostic analysis as a result, judging whether to need to send the operation such as warning information.Doctor can also pass through Browser checks user's electrocardiogram (ECG) data, and provides diagnostic comments.
Fig. 3 is the RdR scatter plot schematic diagram that MIT-BIH electrocardiogram (ECG) data is drawn by MATLAB.RdR scatter plot can have Effect reflection heartbeat interval changes with time trend, contains a large amount of clinical information, can show different heartbeat features.Experiment It has been shown that, carries out identification classification to it using the method for the present invention, effect is preferable.
Fig. 4 is that certain a kind of electrocardiogram (ECG) data sample is randomly choosed from test sample, if figure is to choose concrete class to be It, is calculated the difference of its SPE by some test sample collections of " 3 " with each classification respectively, as a result such as figure (4), it can be seen that its With the SPE difference minimum that classification is " 3 ", classify all correct;
Fig. 5 is that method, the result display diagram of part classifying test display according to the present invention, and accuracy rate is higher, in figure, ginseng Number true is actual sample class, and predicted is the classification of classifier prediction, and the image shown in figure is RdR scatterplot Figure, it can be seen that classification results are all correct.
In conclusion the present invention by calculating sample data and uses core using sparse kernel principle component analysis method is integrated Difference between principal component analysis mapping data carrys out the maximum correlation between data, and judges electrocardiogram (ECG) data with this Classification studies automatic recognition classification RdR scatter plot.It is performed an analysis using the method for the present invention to heart rate variability, can be realization Automated diagnostic, the waste alleviated medical resource in short supply, reduce medical resource improve some bases of medical efficiency offer.
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that being led for this technology For the those of ordinary skill in domain, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications Also it should be regarded as protection scope of the present invention.

Claims (3)

1. a kind of portable cardiac on-line intelligence monitoring diagnosis system design method, which is characterized in that including following main body step:
Step 1) acquires electrocardiosignal, is filtered denoising to electrocardiosignal, extracts R crest value position;
Step 2) draws electrocardio RdR scatter plot using heartbeat interval;
Step 3) zooms in and out electrocardio RdR scatter plot, zooms to same specification, changes into grayscale image, and carry out to image data Normalized, to reduce calculation amount;
The scatter plot sample of acquisition is marked in step 4);
Step 5) samples sample, randomly selects 85% data as training sample;
Parameter is arranged in step 6), and parameter includes the value of the error parameter of approximate base, gaussian kernel function parameter and control limit;
Step 7) solves approximate base, characteristic value, feature vector to every class sample respectively;
Step 8) calculates separately the SPE of each test sample, and the SPE difference reckling of value and certain class sample is test sample Predict classification, compared with concrete class, calculate accuracy rate, the step 9) if meeting the requirements, otherwise return step 6) it resets Parameter training;
Step 9) obtains disaggregated model parameter, and the disaggregated model of acquisition is used in cardiac diagnosis system.
2. a kind of portable cardiac on-line intelligence monitoring diagnosis system design method according to claim 1, feature exist In,
Using integrating sparse kernel principle component analysis method for the Classification and Identification of the electrocardio RdR scatter plot.
3. a kind of portable cardiac on-line intelligence monitoring diagnosis system design method according to claim 2, feature exist In,
Sparse kernel principle component analysis method will be integrated and be used for Classification and Identification to the electrocardio RdR scatter plot, first establish integrate it is dilute Kernel principle component analysis model is dredged, Con trolling index is then selected by square prediction error method.
CN201810921525.7A 2018-08-14 2018-08-14 A kind of portable cardiac on-line intelligence monitoring diagnosis system design method Pending CN109157211A (en)

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CN110403600A (en) * 2019-07-26 2019-11-05 武汉海星通技术股份有限公司 Paroxysmal Atrial Fibrillation intelligent analysis method and system based on differential time scatter plot
CN111920397A (en) * 2020-08-07 2020-11-13 江苏师范大学 Arteriosclerosis degree detection method based on sparse least square support vector machine
CN114496209A (en) * 2022-02-18 2022-05-13 青岛市中心血站 Blood donation intelligent decision method and system

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