CN108922619A - A kind of RdR scatter plot recognition methods based on sparse core leading role - Google Patents

A kind of RdR scatter plot recognition methods based on sparse core leading role Download PDF

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CN108922619A
CN108922619A CN201810756125.5A CN201810756125A CN108922619A CN 108922619 A CN108922619 A CN 108922619A CN 201810756125 A CN201810756125 A CN 201810756125A CN 108922619 A CN108922619 A CN 108922619A
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leading role
sample
scatter plot
rdr
core leading
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岳大超
刘海宽
蒋大伟
张磊
李致远
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Jiangsu Normal University
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00Aspects of pattern recognition specially adapted for signal processing
    • G06F2218/08Feature extraction
    • G06F2218/10Feature extraction by analysing the shape of a waveform, e.g. extracting parameters relating to peaks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00Aspects of pattern recognition specially adapted for signal processing
    • G06F2218/12Classification; Matching

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  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
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  • Databases & Information Systems (AREA)
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  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The present invention discloses a kind of RdR scatter plot recognition methods based on sparse core leading role, and step 1) obtains electrocardiosignal, and filtering and noise reduction extracts R crest value position;Step 2) draws RdR scatter plot using heartbeat interval;Step 3) zooms in and out RdR scatter plot;The scatter plot sample of acquisition is marked in step 4);Step 5) is respectively to every class specimen sample;Step 6) selects different parameters, solves approximate base to every class sample respectively;Each test sample is calculated core leading role with approximate base respectively by step 7), its value the maximum is set as the prediction classification of test sample, compared with concrete class, assesses the performance of classifier, the step 8) if meeting performance indicator, otherwise return step 6) Reparametrization;Step 8) obtains disaggregated model, and algorithm terminates;The present invention carries out the Classification and Identification of heart rate variability using sparse core leading role, has satisfactory classifying quality.

Description

A kind of RdR scatter plot recognition methods based on sparse core leading role
Technical field
The present invention relates to a kind of RdR scatter plot recognition methods based on sparse core leading role, belong to intelligent medical technical field.
Background technique
Cardiovascular disease is unhealthful important killer, in June, 2017《Chinese cardiovascular disease report 2016》Publication.Report It points out:Currently, cardiovascular death accounts for the first place of the total cause of death of urban and rural residents, and 10 years from now on cardiovascular disease numbers of patients are still By rapid growth.In addition, will be about 23,300,000 people according to the report of the World Health Organization to the year two thousand thirty and died of cardiovascular disease. In face of this trend, the early diagnosis and prevention of cardiovascular disease are particularly important.
Traditional diagnostic method is patient to hospital, and doctor carries out ECG examination to it, and then provides diagnostic result, is appointed It is engaged in heavy and doctor is needed to have clinical experience abundant and professional knowledge;And rare medical resource, it is difficult to meet substantial amounts The requirement of PATIENT POPULATION.In order to improve medical efficiency, convenience and agility, there is automated diagnostic technology, assist doctor It is diagnosed.
Heart rate variability refers to the time-variance number between cardiac cycle, and research object is cardiac cycle rather than heart rate. The heart rate of people be not it is unalterable, there is small time differences between heartbeat twice, calculate the difference of cardiac cycle, i.e., It can be appreciated that heart rate variability (Heart rate variability, HRV).
Heart rate variability can assess the influence of cardiac sympathetic nerve and parasympathetic nerve to cardiovascular activity, contain the heart Bulk information in terms of blood vessel.Clinical research shows that the reduction of heart rate variability is the hearts such as myocardial infarction, hypertension, angina pectoris The symptom of vascular morbidity.Therefore, the research of heart rate variability, in evaluation systema cariovasculare functional, prediction cardiovascular disease Breaking-out, and have great importance for the early diagnosis of cardiovascular disease.
Poincare scatter plot is a kind of important research method of heart rate variability:Existed by using continuous heartbeat interval Graphing in rectangular coordinate system reflects the variation of adjacent heartbeat interval, can show the feature of heartbeat interval;Poincare scatterplot For figure there are many form, including comet formation, sector etc., different shapes reflects different heart states.
Although Poincare scatter plot is a kind of effective heart rate variance analyzing method, it can not be embodied at any time Between the trend that changes, its heart rate variability property cannot be embodied well for certain cardiovascular diseases, physical condition etc.. Then, some scholars propose improvement strategy, i.e. first order difference plot, draw scatterplot by the difference of adjacent heartbeat interval Figure.However, this method is lost the absolute value information of original heartbeat interval again;Therefore, and scholar combines the two, A kind of RdR scatter plot is proposed, come with this while reflecting heartbeat interval and its variation.
Currently, many for the heart rate variability analysis of different cardiovascular diseases;But how according to scatter plot come automatic It identifies, to distinguish different cardiovascular diseases then relatively deficient.
Summary of the invention
The object of the invention is that providing a kind of RdR scatter plot based on sparse core leading role to solve the above-mentioned problems Recognition methods, can automatic recognition classification RdR scatter plot, perform an analysis to heart rate variability, for realize automated diagnostic, alleviate it is tight The waste of scarce medical resource, reduction medical resource improves medical efficiency offer basis.
The present invention is achieved through the following technical solutions above-mentioned purpose:A kind of RdR scatter plot knowledge based on sparse core leading role Other method, includes the following steps:
Step 1) obtains electrocardiosignal, is filtered denoising to electrocardiosignal, extracts R crest value position;
Step 2) draws RdR scatter plot using heartbeat interval, can be drawn by MATLAB tool;
Step 3) zooms in and out RdR scatter plot, grayscale image is changed into, and image data is normalized, to subtract Few calculation amount;
The scatter plot sample of acquisition is marked in step 4);
Step 5) randomly selects wherein 80% data as training sample respectively to every class specimen sample, remaining 20% is used as test sample;
Step 6) selects different parameters, solves approximate base to every class sample respectively;
Each test sample is calculated core leading role with approximate base respectively by step 7), and value the maximum is set as the pre- of test sample Classification is surveyed, compared with concrete class, assesses the performance of classifier, the step 8) if meeting performance indicator, otherwise return step 6) Reparametrization;
Step 8) obtains disaggregated model, and algorithm terminates.
The basic skills of sparse core leading role:
Leading role (Principal Angle, PA) is a kind of parameter for relationship between metric data collection, studies two numbers The correlation of data is analyzed according to the minimum angle of subspace;
Assuming that X and Y are the stochastic variable of two zero-means, [a1,...,aN] and [b1,...,bM] it is in X and Y respectively Two samples;Enable A=[a1,...,aN], B=[b1,...,bM], it is U there are two subspaceA=span { a1,...,aNAnd UB= span{b1,...,bMIt is two sub-spaces;θ is the leading role of the two subspaces, is met:
For convenient for calculating, formula (1) is newly defined as:
The Lagrangian of structural formula (2):
Above formula asks local derviation to obtain x, y:
α and β is the unique variable in two local derviation formulas respectively, thus 2 α in local derviation formula and 2 β can be newly defined as α and β, it is easy to derive to draw a conclusion:
Eigenvalue problem below is summarized as to solve:
Further two formulas are merged into:
The shortcomings that in order to solve the problems, such as nonlinear correlation, overcome conventional linear leading role's method, numerous scholars draw kernel function Enter in leading role, produces core leading role (Kernel Principal Angle, KPA);
Assuming that Nonlinear Mapping T is by the vector a of the input spacekIt is mapped in high-dimensional feature space, then hasWithFormula (2) can be write as:
Be converted to eigenvalue problem:
After introducing Kernel-Based Methods,It can be described with nuclear matrix, formula (9) Maximum eigenvalue λl, i.e. λl=cos θ is characterized subspace UAAnd UBThe cosine value of angle;And when sample number is larger, it solves It will appear difficulty, in addition, core leading role is easy to appear overfitting, it is therefore desirable to sparse core leading role (Sparse Kernel Principal Angle,SKPA);
According to formula (2) it can be found that Ax and yTBTIt is the linear combination of sample space, if finding the base of sample A and B, just Ax and y can be replaced with the linear combination of baseTBT;Without loss of generality, it is assumed thatIt may determine that by following formula It can be by ΦAIn the linear combination table of other samples show:
Solution procedure is as follows:
By Lagrange conditionObtain -2K0λ=0+2K, wherein K0=(k (x1,xk),…,k(xl,xk))T, the side of being K It structures the formation, Kij=k (xi,xj);When kernel function is gaussian radial basis function, matrix K positive definite obtains λmin=K-1K0
It is comprised the concrete steps that in the step 6) like what base solved:
A. set is establishedFor approximate Maximum independent group, XA=φ;
B. for k=2 ..., N'sMinimizing value;
C. if obtaining minimum value≤ε, corresponding element is added in XA, is otherwise Xl;
ε is linearly related truncated error, asks the base of infinite dimensional space almost without sparsity in limited sample, therefore Select approximate calculation;
Return step B), until completing all calculating, calculating terminates;
It is solved by approximate base, ΦAIt is split into two set Xl、XA, XlIn element Line independent, XAIn element can be with By XlLinear combination indicates, even if ε will lead to error, but according to Statistical Learning Theory, to control the learning ability of core leading role;ΦB Similarly, BlIn element Line independent;At this point, formula (8) solution is simplified, it is equivalent to solve eigenvalue problem below:
It is sparse core leading role.
Compared with prior art, the present invention is ground using sparse core leading role method by the minimum angle between metric data Study carefully its correlation and carrys out automatic recognition classification RdR scatter plot.It is performed an analysis using the method for the present invention to heart rate variability, can be real Existing automated diagnostic, the waste alleviated medical resource in short supply, reduce medical resource, the medical efficiency of raising provide some bases.
Detailed description of the invention
Fig. 1 is specific method flow chart of the present invention;
Fig. 2 is RdR scatter plot;
Fig. 3 is the partial test result figure with test data testing classification device performance.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
As shown in Fig. 1, a kind of RdR scatter plot recognition methods based on sparse core leading role, includes the following steps:
Step 1) obtains electrocardiosignal, is filtered denoising to electrocardiosignal, extracts R crest value position;
Step 2) draws RdR scatter plot using heartbeat interval, can be drawn by MATLAB tool;
Step 3) zooms in and out RdR scatter plot, grayscale image is changed into, and image data is normalized, to subtract Few calculation amount;
The scatter plot sample of acquisition is marked in step 4);
Step 5) randomly selects wherein 80% data as training sample respectively to every class specimen sample, remaining 20% is used as test sample;
Step 6) selects different parameters, solves approximate base to every class sample respectively;
Each test sample is calculated core leading role with approximate base respectively by step 7), and value the maximum is set as the pre- of test sample Classification is surveyed, compared with concrete class, assesses the performance of classifier, the step 8) if meeting performance indicator, otherwise return step 6) Reparametrization;
Step 8) obtains disaggregated model, and algorithm terminates.
Wherein, the basic skills of sparse core leading role:
Leading role (Principal Angle, PA) is a kind of parameter for relationship between metric data collection, studies two numbers The correlation of data is analyzed according to the minimum angle of subspace;
Assuming that X and Y are the stochastic variable of two zero-means, [a1,...,aN] and [b1,...,bM] it is in X and Y respectively Two samples;Enable A=[a1,...,aN], B=[b1,...,bM], it is U there are two subspaceA=span { a1,...,aNAnd UB= span{b1,...,bMIt is two sub-spaces;θ is the leading role of the two subspaces, is met:
For convenient for calculating, formula (1) is newly defined as:
The Lagrangian of structural formula (2):
Above formula asks local derviation to obtain x, y:
α and β is the unique variable in two local derviation formulas respectively, thus 2 α in local derviation formula and 2 β can be newly defined as α and β, it is easy to derive to draw a conclusion:
Eigenvalue problem below is summarized as to solve:
Further two formulas are merged into:
The shortcomings that in order to solve the problems, such as nonlinear correlation, overcome conventional linear leading role's method, numerous scholars draw kernel function Enter in leading role, produces core leading role (Kernel Principal Angle, KPA);
Assuming that Nonlinear Mapping T is by the vector a of the input spacekIt is mapped in high-dimensional feature space, then hasWithFormula (2) can be write as:
Be converted to eigenvalue problem:
After introducing Kernel-Based Methods,It can be described with nuclear matrix, formula (9) Maximum eigenvalue λl, i.e. λl=cos θ is characterized subspace UAAnd UBThe cosine value of angle;And when sample number is larger, it solves It will appear difficulty, in addition, core leading role is easy to appear overfitting, it is therefore desirable to sparse core leading role (Sparse Kernel Principal Angle,SKPA);
According to formula (2) it can be found that Ax and yTBTIt is the linear combination of sample space, if finding the base of sample A and B, just Ax and y can be replaced with the linear combination of baseTBT;Without loss of generality, it is assumed thatIt may determine that by following formula It can be by ΦAIn the linear combination table of other samples show:
Solution procedure is as follows:
By Lagrange conditionObtain -2K0λ=0+2K, wherein K0=(k (x1,xk),…,k(xl,xk))T, the side of being K cloth Battle array, Kij=k (xi,xj);When kernel function is gaussian radial basis function, matrix K positive definite obtains λmin=K-1K0
Wherein, it is comprised the concrete steps that in the step 6) like what base solved:
A. set is establishedFor approximate Maximum independent group, XA=φ;
B. for k=2 ..., N'sMinimizing value;
C. if obtaining minimum value≤ε, corresponding element is added in XA, is otherwise Xl;
ε is linearly related truncated error, asks the base of infinite dimensional space almost without sparsity in limited sample, therefore Select approximate calculation;
Return step 2), until completing all calculating, calculating terminates;
It is solved by approximate base, ΦAIt is split into two set Xl、XA, XlIn element Line independent, XAIn element can be with By XlLinear combination indicates, even if ε will lead to error, but according to Statistical Learning Theory, to control the learning ability of core leading role;ΦB Similarly, BlIn element Line independent;At this point, formula (8) solution is simplified, it is equivalent to solve eigenvalue problem below:
It is sparse core leading role.
Using the electrocardiogram (ECG) data in MIT-BIH database, to make schematically analysis with the data of this database convenient for narration It introduces.
Fig. 2 is the RdR scatter plot that MIT-BIH electrocardiogram (ECG) data is drawn by MATLAB.RdR scatter plot can effectively reflect Heartbeat interval changes with time trend, contains a large amount of clinical information, can show different heartbeat features.Experiment display, makes Identification classification is carried out to it with the method for the present invention, effect is preferable.
Fig. 3 is that method, the result display diagram of part classifying test display according to the present invention, and accuracy rate is higher, in figure, ginseng Number true is actual sample class, and predicted is the classification of classifier prediction, and the image shown in figure is RdR scatter plot.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (3)

1. a kind of RdR scatter plot recognition methods based on sparse core leading role, which is characterized in that include the following steps:
Step 1) obtains electrocardiosignal, is filtered denoising to electrocardiosignal, extracts R crest value position;
Step 2) draws RdR scatter plot using heartbeat interval, can be drawn by MATLAB tool;
Step 3) zooms in and out RdR scatter plot, changes into grayscale image, and image data is normalized, in terms of reducing Calculation amount;
The scatter plot sample of acquisition is marked in step 4);
Step 5) respectively to every class specimen sample, make as training sample, remaining 20% by the data for randomly selecting wherein 80% For test sample;
Step 6) selects different parameters, solves approximate base to every class sample respectively;
Each test sample is calculated core leading role with approximate base respectively by step 7), and value the maximum is set as the prediction class of test sample Not, compared with concrete class, the performance of classifier is assessed, the step 8) if meeting performance indicator, otherwise return step 6) again Parameter is set;
Step 8) obtains disaggregated model, and algorithm terminates.
2. a kind of RdR scatter plot recognition methods based on sparse core leading role according to claim 1, it is characterised in that:It is dilute Dredge the basic skills of core leading role:
Leading role (Principal Angle, PA) is a kind of parameter for relationship between metric data collection, studies two data The minimum angle in space analyzes the correlations of data;
Assuming that X and Y are the stochastic variable of two zero-means, [a1,...,aN] and [b1,...,bM] it is two samples in X and Y respectively This;Enable A=[a1,...,aN], B=[b1,...,bM], it is U there are two subspaceA=span { a1,...,aNAnd UB=span {b1,...,bMIt is two sub-spaces;θ is the leading role of the two subspaces, is met:
For convenient for calculating, formula (1) is newly defined as:
The Lagrangian of structural formula (2):
Above formula asks local derviation to obtain x, y:
α and β is the unique variable in two local derviation formulas respectively, therefore 2 α in local derviation formula and 2 β can be newly defined as α and β, very It is easy to derive to draw a conclusion:
Eigenvalue problem below is summarized as to solve:
Further two formulas are merged into:
The shortcomings that in order to solve the problems, such as nonlinear correlation, overcome conventional linear leading role's method, kernel function is introduced by numerous scholars In leading role, core leading role (Kernel Principal Angle, KPA) is produced;
Assuming that Nonlinear Mapping T is by the vector a of the input spacekIt is mapped in high-dimensional feature space, then hasWithFormula (2) can be write as:
Be converted to eigenvalue problem:
After introducing Kernel-Based Methods,It can be described with nuclear matrix, formula (9) is most Big eigenvalue λl, i.e. λl=cos θ is characterized subspace UAAnd UBThe cosine value of angle;And when sample number is larger, solution can go out Existing difficulty, in addition, core leading role is easy to appear overfitting, it is therefore desirable to sparse core leading role (Sparse Kernel Principal Angle,SKPA);
According to formula (2) it can be found that Ax and yTBTIt is the linear combination of sample space, if finding the base of sample A and B, so that it may Ax and y are replaced with the linear combination of baseTBT;Without loss of generality, it is assumed thatIt may determine that by following formulaIt can By ΦAIn the linear combination table of other samples show:
Solution procedure is as follows:
By Lagrange conditionObtain -2K0λ=0+2K, wherein K0=(k (x1,xk),…,k(xl,xk))T, the side of being K structures the formation, Kij=k (xi,xj);When kernel function is gaussian radial basis function, matrix K positive definite obtains λmin=K-1K0
3. a kind of RdR scatter plot recognition methods based on sparse core leading role according to claim 1, it is characterised in that:Institute It is comprised the concrete steps that in the step 6) stated like what base solved:
A. set is establishedFor approximate Maximum independent group, XA=φ;
B. for k=2 ..., N'sMinimizing value;
C. if obtaining minimum value≤ε, corresponding element is added in XA, is otherwise Xl;
ε is linearly related truncated error, asks the base of infinite dimensional space almost without sparsity in limited sample, therefore is selected Approximate calculation;
Return step B), until completing all calculating, calculating terminates;
It is solved by approximate base, ΦAIt is split into two set Xl、XA, XlIn element Line independent, XAIn element can be by Xl Linear combination indicates, even if ε will lead to error, but according to Statistical Learning Theory, to control the learning ability of core leading role;ΦBTogether Reason, BlIn element Line independent;At this point, formula (8) solution is simplified, it is equivalent to solve eigenvalue problem below:
It is sparse core leading role.
CN201810756125.5A 2018-07-11 2018-07-11 A kind of RdR scatter plot recognition methods based on sparse core leading role Pending CN108922619A (en)

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