CN109142489A - A kind of electrochemistry test paper and application method of tape identification impedance - Google Patents
A kind of electrochemistry test paper and application method of tape identification impedance Download PDFInfo
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- CN109142489A CN109142489A CN201811122671.XA CN201811122671A CN109142489A CN 109142489 A CN109142489 A CN 109142489A CN 201811122671 A CN201811122671 A CN 201811122671A CN 109142489 A CN109142489 A CN 109142489A
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- test paper
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- tape identification
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
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Abstract
The invention belongs to electrochemical technology fields, the electrochemistry test paper and application method of a kind of tape identification impedance are disclosed, successively the impedance of fitting band identifies test paper substrate layer, electrochemistry gold electrode layer, coating, enzyme layer, upper interlayer to the electrochemistry test paper of the tape identification impedance from the bottom to top.The electrochemistry gold electrode layer is gold electrode or carbon silver electrode.Band impedance mark test paper substrate layer uses polyethylene terephthalate, polyvinyl chloride, any one material in polypropylene.The electrochemistry gold electrode layer is made of the gold electrode of electrochemical working electrode, electrochemical working electrode, trigger electrode, the processing procedure control for connecting electrode and resistance identified areas.The present invention realizes the technology of an electrochemistry test paper automatic identification with impedance mark for the first time;So that different types of test paper, is tested instrument automatic identification by the measurement to modulation impedance, achievees the purpose that automatic identification parameter, be increased without test paper pin.
Description
Technical field
The invention belongs to the electrochemistry test papers and user of electrochemical technology field more particularly to a kind of tape identification impedance
Method.
Background technique
Currently, the prior art commonly used in the trade is such thatCharacterizing human body, whether Jian Kang index has very much, for example blood is normal
Rule, blood lipid, blood pressure, blood glucose, heart rate, acid or alkali environment etc. in human body, and these indexs are needed to the hospital of profession, use profession
Measuring instrument can just measure, for sub-health population or patient with corresponding illness, above-mentioned measurement is very
Therefore there is the portable tester of some households, such as blood-sugar detecting instrument on the market in inconvenience, blood lipid tester, uric acid are surveyed
Try instrument, cholesterol test instrument etc. and corresponding test paper.When the instrument is measured using All-in-One when the test paper for integrating All-in-One, it needs
Pin identification technology is done to test paper, and instrument could be facilitated to the automatic identification of test paper.Only the pin of test paper is encoded,
Multifunctional tester could be made to identify corresponding test strips type.When multifunctional tester will integrate a variety of test functions
When, it is desirable that test paper pin it is more and more, the width of test paper will increase, to increase the electrode print difficulty of test paper.
In conclusion problem of the existing technology is:Multifunctional tester integrates a variety of test function test paper pins and gets over
Come more, the width of test paper increases, and increases the electrode print difficulty of test paper.
Summary of the invention
In view of the problems of the existing technology, the present invention provides a kind of electrochemistry test paper of tape identification impedance and users
Method.
The invention is realized in this way a kind of electrochemistry test paper of tape identification impedance, the electrochemistry of the tape identification impedance
Successively the impedance of fitting band identifies test paper substrate layer, electrochemistry gold electrode layer, coating, enzyme layer, upper interlayer to test paper from the bottom to top.
Further, the electrochemistry gold electrode layer is gold electrode or carbon silver electrode.
Further, the band impedance mark test paper substrate layer uses polyethylene terephthalate, polyvinyl chloride, polypropylene
In any one material.
Further, the electrochemistry gold electrode layer by electrochemical working electrode, electrochemical working electrode, trigger electrode, connect
The gold electrode composition of the processing procedure of energization pole and resistance identified areas control;
According to end of sucking blood top distance by closely to remote sequence be successively electrochemical working electrode, electrochemical operation electricity
Pole, HCT measuring electrode, trigger electrode and impedance identify electrode.
Further, the connection electrode is arranged at the insertion end of electrochemistry gold electrode layer, in electrochemical working electrode and
It connects and a gold electrode resistance modulation areas is set between electrode.
Further, there is stomata in the coating upper end.
It is described another object of the present invention is to provide a kind of application method of the electrochemistry test paper of tape identification impedance
The application method of the electrochemistry test paper of tape identification impedance includes: the type of test paper by electrochemical working electrode, connects electrode and surveys
Test-object is known resistance and is determined, controls the length L of resistance identified areas electrode, width w or thickness d to modulate, reaches different test paper
The automatic identification of type;The resistance Rin connected between electrode can react the type of test paper.By measuring Rin, test paper is determined
Type, the electric current vs of the different type test paper pre-seted in corresponding instrument measure concentration curve library to measure target in blood
The concentration of substance.
In conclusion advantages of the present invention and good effect are as follows:The electrochemical test with impedance mark is realized for the first time
The technology of paper automatic identification;So that different types of test paper, is tested instrument automatic identification by the measurement to modulation impedance, reaches
The purpose of automatic identification parameter is increased without test paper pin.
Detailed description of the invention
Fig. 1 is the electrochemistry test paper structural schematic diagram of tape identification impedance provided in an embodiment of the present invention;
In figure: 1, band impedance identifies test paper substrate layer;2, electrochemistry gold electrode layer;2-1, electrochemical working electrode;2-2,
Electrochemistry is to electrode;2-3, HCT measuring electrode;2-4, trigger electrode;2-5, resistance identified areas;2-6, electrode is connected;3, it covers
Cap rock;4, enzyme layer;4-1, reaction zone;5, upper interlayer;5-1, stomata.
Fig. 2 is resistance landmark identification regional structure schematic diagram provided in an embodiment of the present invention.
Specific embodiment
In order to further understand the content, features and effects of the present invention, the following examples are hereby given, and cooperate attached drawing
Detailed description are as follows.
As shown in Figure 1, the electrochemistry test paper of tape identification impedance provided in an embodiment of the present invention includes: that band impedance identifies test paper
Substrate layer 1, electrochemistry gold electrode layer 2, coating 3, enzyme layer 4, upper interlayer 5.
The electrochemistry test paper of tape identification impedance provided in an embodiment of the present invention successively identifies test paper by band impedance from the bottom to top
Substrate layer 1, electrochemistry gold electrode layer 2, coating 3, enzyme layer 4, upper interlayer 5 are bonded.
Electrochemistry gold electrode layer 2 is gold electrode or carbon silver electrode.
Band impedance mark test paper substrate layer 1 preferably uses polyethylene terephthalate, polyvinyl chloride, appointing in polypropylene
It anticipates the substrate layer of material a kind of.
Electrochemistry gold electrode layer 2 preferably by electrochemical working electrode 2-1, electrochemical working electrode 2-2, trigger electrode 2-4,
Connect the gold electrode composition of the processing procedure control of electrode 2-6 and resistance identified areas 2-5;And according to the distance on the top at end of sucking blood by
It is closely successively electrochemical working electrode 2-1, electrochemical working electrode 2-2, HCT (red blood cell overstocks ratio) measurement electricity to remote sequence
Pole 2-3, trigger electrode 2-4 and impedance identify electrode, connect electrode 2-6 and are arranged at the insertion end of electrochemistry gold electrode layer 2,
It electrochemical working electrode 2-2 and connects a gold electrode resistance modulation areas is set between electrode 2-6, resistance is by the length modulated
Spend L, width w or thickness d label.
Preferably there is stomata 5-1 in 3 upper end of coating.
The electrochemistry test paper of tape identification impedance provided in an embodiment of the present invention pre-sets the survey corresponding to different test paper types
Quantity algorithm, the type of every kind of test paper can connect electrode 2-6 test mark resistance by electrochemical working electrode 2-2 to determine,
The length L of resistance identified areas 2-5 electrode, width w or thickness d are controlled to modulate, reaches the automatic knowledge of different test paper types
Not, that is, electrochemical working electrode 2-2, the resistance Rin connected between electrode 2-6 can react the type of test paper.Pass through survey
Rin is measured, determines the type of test paper, so that the electric current vs measurement concentration of the different type test paper pre-seted in corresponding instrument is bent
Line library measures the concentration of target substance in blood.
Application principle of the invention is further described with reference to the accompanying drawing.
Band impedance identifies test paper substrate layer 1: using polyethylene terephthalate (PET), polyvinyl chloride (PVC), polypropylene
One of (PP).
Electrochemistry gold electrode layer 2: material selection gold is used.Including electrochemical working electrode 2-1, electrochemistry to electrode 2-2,
HCT measuring electrode 2-3, trigger electrode 2-4, resistance identified areas 2-5, electrode 2-6 is connected.Electrochemical working electrode 2-1 and electricity
Chemistry is measured to electrode 2-2, to the intracorporal blood sample of chamber, by temperature adjustmemt and the HCT parameter of measurement to measured value
It is modified, the concentration measurement of this measured object is finally shown on corresponding tester.
HCT measurement: a pair of electrode for measuring blood conductance that HCT measuring electrode 2-3 and electrochemistry forms electrode 2-2
It is right, the HCT parameter of blood is calculated by the conductance of measurement.
Trigger electrode 2-4 is located at the bottom of reaction cavity, must reach bottom after blood is from top into end of sucking blood
Trigger electrode test paper can just issue measurement countdown to corresponding tester, tester starts countdown test, trigger electrode
Design can to avoid due to blood not fill measured value caused by entire reaction zone inaccuracy;It is one of to connect electrode 2-
6 are located at the bottom of test paper, when test paper is inserted into corresponding tester, the both ends of connection electrode and disconnecting circuit in combined measuring instrument
Be connected so that the circuit of test paper circuit and tester constitutes complete circuit, instrument will Auto Power On, extracted out after being measured
Test strips, instrument will automatic shutdowns.The impedance of resistance identified areas 2-5 by electrode length or width or thickness tune
System modulates different impedances (such as when connecting electrode 2-6 and electrochemistry pair to impedance tag slot according to different test paper types
When resistance Rin=R1 between electrode 2-2, this test paper examination blood sugar test paper is represented, as Rin=R2, represents this test paper examination uric acid
Test paper, as Rin=Rn, representing the examination of this test paper is N type test strips) enzyme layer 4, the enzyme that electrochemical reaction occurs is provided.Covering
Layer 3: it is used to covering part electrochemistry gold electrode layer 2, there is a stomata 5-1 in the front end of the coating 3, enters rainbow for blood is discharged
Inhale air when channel.
Upper interlayer 5: positioned at the upper end of interval coating 3, for protecting reaction zone not by the interference of external environment.
As shown in Fig. 2, for resistance landmark identification region:
The resistance value in resistance landmark identification region can use R5It indicates:
The resistance between electrode 2-2 can be indicated by connecting electrode 2-6 and electrochemistry are as follows:
Rin=R0+R5, wherein R0Size be far below R5;
Therefore by the total length L of the ring structure of resistance identified areas 2-5 or width w or thickness d come mark not
Same electrochemical detection test strip, such as when measurement connects electrode 2-6 and electrochemistry to the resistance R between electrode 2-2in=R1When, generation
This test paper of table tries blood sugar test paper, works as Rin=R2When, this test paper examination uric acid test paper is represented, R is worked asin=RnWhen, representing the examination of this test paper is N
Type test strips.
The above is only the preferred embodiments of the present invention, and is not intended to limit the present invention in any form,
Any simple modification made to the above embodiment according to the technical essence of the invention, equivalent variations and modification, belong to
In the range of technical solution of the present invention.
Claims (7)
1. a kind of electrochemistry test paper of tape identification impedance, which is characterized in that the electrochemistry test paper of the tape identification impedance by down toward
On successively fitting band impedance identify test paper substrate layer, electrochemistry gold electrode layer, coating, enzyme layer, upper interlayer.
2. the electrochemistry test paper of tape identification impedance as described in claim 1, which is characterized in that the electrochemistry gold electrode layer is
Gold electrode or carbon silver electrode.
3. the electrochemistry test paper of tape identification impedance as described in claim 1, which is characterized in that the band impedance identifies test paper base
Lamella uses polyethylene terephthalate, polyvinyl chloride, any one material in polypropylene.
4. the electrochemistry test paper of tape identification impedance as described in claim 1, which is characterized in that the electrochemistry gold electrode layer by
Electrochemical working electrode, electrochemical working electrode, trigger electrode, the gold for the processing procedure control for connecting electrode and resistance identified areas are electric
Pole composition;
According to end of sucking blood top distance by closely to remote sequence be successively electrochemical working electrode, electrochemical working electrode,
HCT measuring electrode, trigger electrode and impedance identify electrode.
5. the electrochemistry test paper of tape identification impedance as claimed in claim 4, which is characterized in that the connection electrode is arranged in electricity
At the insertion end of chemical gold electrode layer, in electrochemical working electrode and one gold electrode resistance modulator zone of setting between electrode is connected
Domain.
6. the electrochemistry test paper of tape identification impedance as described in claim 1, which is characterized in that there is gas in the coating upper end
Hole.
7. a kind of application method of the electrochemistry test paper of tape identification impedance as described in claim 1, which is characterized in that the band mark
The application method of the electrochemistry test paper of knowledge impedance includes: the type of test paper by electrochemical working electrode, connects electrode test mark
Know resistance to determine, controls the length L of resistance identified areas electrode, width w or thickness d to modulate, reach different test paper types
Automatic identification;The resistance Rin connected between electrode can react the type of test paper.By measuring Rin, the class of test paper is determined
Type, the electric current vs of the different type test paper pre-seted in corresponding instrument measure concentration curve library to measure object in blood
The concentration of matter.
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Cited By (1)
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CN114778631A (en) * | 2022-06-17 | 2022-07-22 | 北京华益精点生物技术有限公司 | Body index detection device and method |
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CN105973946A (en) * | 2016-05-05 | 2016-09-28 | 四川拉雅微科技有限公司 | High-precision blood sugar test paper with hematokrit measurement and compensation function |
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CN101430327A (en) * | 2007-11-08 | 2009-05-13 | 厚美德生物科技股份有限公司 | Detection test piece with recognition function and its detection apparatus |
US20150136617A1 (en) * | 2013-11-19 | 2015-05-21 | Apex Biotechnology Corp. | Hematocrit measurement system and measurement method using the same |
CN105973946A (en) * | 2016-05-05 | 2016-09-28 | 四川拉雅微科技有限公司 | High-precision blood sugar test paper with hematokrit measurement and compensation function |
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