CN109124620A - A kind of atrial fibrillation detection method, device and equipment - Google Patents

A kind of atrial fibrillation detection method, device and equipment Download PDF

Info

Publication number
CN109124620A
CN109124620A CN201810580271.7A CN201810580271A CN109124620A CN 109124620 A CN109124620 A CN 109124620A CN 201810580271 A CN201810580271 A CN 201810580271A CN 109124620 A CN109124620 A CN 109124620A
Authority
CN
China
Prior art keywords
heartbeat waveform
atrial fibrillation
time
heartbeat
frequency spectrum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810580271.7A
Other languages
Chinese (zh)
Other versions
CN109124620B (en
Inventor
张恒贵
李钦策
刘阳
何润南
赵娜
王宽全
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Green Star Space Technology Co ltd
Spacenter Space Science And Technology Institute
Original Assignee
Space Institute Of Southern China (shenzhen)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Space Institute Of Southern China (shenzhen) filed Critical Space Institute Of Southern China (shenzhen)
Priority to CN201810580271.7A priority Critical patent/CN109124620B/en
Publication of CN109124620A publication Critical patent/CN109124620A/en
Application granted granted Critical
Publication of CN109124620B publication Critical patent/CN109124620B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/361Detecting fibrillation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device

Abstract

The application belongs to field of medical device, and disclosing a kind of atrial fibrillation detection method includes: extraction heartbeat waveform relevant to RR interphase;Continuous wavelet transform is carried out to the heartbeat waveform, reconstructs the time-frequency spectrum tensor of heartbeat waveform;The depth convolutional neural networks completed by training carry out feature learning and classification to the time-frequency spectrum system structure of heartbeat waveform, obtain the testing result of the heartbeat waveform.The application can reflect the movable correlation properties of atrium and ventricle simultaneously, signal characteristic can significantly more be embodied, feature learning and classification are carried out to heartbeat waveform time-frequency spectrum tensor using depth convolutional neural networks, avoid workload and one-sidedness of the conventional method in feature extraction, there is stronger adaptability for the training sample of new type, to help to promote nicety of grading.

Description

A kind of atrial fibrillation detection method, device and equipment
Technical field
The application belongs to field of medical device more particularly to a kind of atrial fibrillation detection method, device and equipment.
Background technique
Auricular fibrillation (abbreviation atrial fibrillation) is the arrhythmia status of a kind of high-incidence in crowd (disease incidence is about 1~2%). It is damaged not only for the health of patient, but will increase the risk of a variety of diseases such as apoplexy, myocardial infarction, and it is raw to jeopardize patient Life.The disease incidence of atrial fibrillation is positively correlated with the age, and crowd's disease incidence is up to 10% within 75 years old or more.It is aged along with the population in China Change trend, the preventing and controlling of atrial fibrillation will be a stern challenges.
The detection of atrial fibrillation relies primarily on the manual inspection of electrocardiogram at present, and diagnostic accuracy depends on the specialized water of doctor It puts down and biggish variation is presented.The artificial inspection of electrocardiogram (especially long term monitoring electrocardiogram, such as 24 hr Ambulatory EKG Monitorings) It looks into and needs to consume a large amount of manpower, the burden got worse is brought to medical department.In addition, with the development of mobile internet, The cardioelectric monitor equipment of household becomes increasingly popular, the mass data that thus will bring manual inspection that can not cope with.Therefore, electrocardio is believed Number automatically analyze the urgent need for becoming current social with disease detection technology.
The automatic testing method of atrial fibrillation includes mode identification method based on electro-cardiologic signal waveforms and based on RR interphase at present Heart-rate variability analysis method, what the former reflected is atrial activity, influence of the atrial activity of the latter's reflection to ventricular activity. Method based on heart-rate variability has the ability for resisting noise jamming more by force, however by the limitation of its information content, precision is logical Often it is difficult to meet demand.
Summary of the invention
In view of this, the embodiment of the present application provides a kind of atrial fibrillation detection method, device and equipment, to solve the prior art In due to heart-rate variability limitation of the method by its information content, the problem of precision is generally difficult to meet demand.
The first aspect of the embodiment of the present application provides a kind of atrial fibrillation detection method, and the atrial fibrillation detection method includes:
Extract heartbeat waveform relevant to RR interphase;
Continuous wavelet transform is carried out to the heartbeat waveform, reconstructs the time-frequency spectrum tensor of heartbeat waveform;
The depth convolutional neural networks completed by training carry out feature learning to the time-frequency spectrum system structure of heartbeat waveform And classification, obtain the testing result of the heartbeat waveform.
With reference to first aspect, in the first possible implementation of first aspect, the extraction is relevant to RR interphase The step of heartbeat waveform includes:
The R wave wave crest in electrocardiosignal is detected by Pan's Tompkins Pan-Tompkins algorithm;
According to R wave crest location, heartbeat waveform list is intercepted.
The possible implementation of with reference to first aspect the first, in second of possible implementation of first aspect, institute In the step of stating according to R wave crest location, intercepting heartbeat waveform list, for i-th heartbeat, the initial position (S of waveformi) With final position (Ei) calculation formula it is as follows:
Ri indicates the position (sampled point) of i-th of the R wave wave crest detected in the signal, and the value range of i is 2 to N-1, N is the R wave wave crest sum detected.
With reference to first aspect, described that the heartbeat waveform is carried out in the third possible implementation of first aspect Continuous wavelet transform, the step of reconstructing the time-frequency spectrum tensor of heartbeat waveform include:
Utilize continuous wavelet transform formulaObtain each heartbeat The two-dimentional time-frequency spectrum of waveform, wherein a and b is respectively scale factor and shift factor, and f (t) is the signal of output, and Ψ is small echo Basic function;
The time-frequency spectrum of acquisition is zoomed into uniform sizes;
The time-frequency spectrum of continuous multiple heartbeat waveforms is superposed to a three-dimensional tensor in order, three of them dimension is followed successively by frequency Rate, time and heart sequence.
With reference to first aspect, related to RR interphase in the extraction in the 4th kind of possible implementation of first aspect Heartbeat waveform the step of before, the method also includes:
Signal is smoothed using rolling average counting method, removes the baseline drift signal in electrocardiosignal;
Utilize the noise in soft-threshold Wavelet noise-eliminating method removal electrocardiosignal.
The second aspect of the embodiment of the present application provides a kind of atrial fibrillation detection device, and the atrial fibrillation detection device includes:
Heartbeat waveform extraction unit, for extracting heartbeat waveform relevant to RR interphase;
Time-frequency spectrum tensor reconfiguration unit reconstructs heartbeat waveform for carrying out continuous wavelet transform to the heartbeat waveform Time-frequency spectrum tensor;
Learning classification unit, for the depth convolutional neural networks by training completion to the time-frequency spectra system of heartbeat waveform Structure carries out feature learning and classification, obtains the testing result of the heartbeat waveform.
In conjunction with second aspect, in the first possible implementation of second aspect, the heartbeat waveform extraction unit packet It includes:
Wave crest detection sub-unit, for detecting the R wave in electrocardiosignal by Pan's Tompkins Pan-Tompkins algorithm Wave crest;
Waveform list interception unit, for intercepting heartbeat waveform list according to R wave crest location.
In conjunction with second aspect, in second of possible implementation of second aspect, the time-frequency spectrum tensor reconfiguration unit Include:
Subelement is converted, for utilizing continuous wavelet transform formula
The two-dimentional time-frequency spectrum of each heartbeat waveform is obtained, In, a and b are respectively scale factor and shift factor, and f (t) is the signal of output, and Ψ is wavelet basis function;
Subelement is scaled, for the time-frequency spectrum of acquisition to be zoomed to uniform sizes;
It is superimposed subelement, for the time-frequency spectrum of continuous multiple heartbeat waveforms to be superposed to a three-dimensional tensor in order, Three dimensions are followed successively by frequency, time and heart sequence.
The third aspect of the embodiment of the present application provides a kind of atrial fibrillation detection device, including memory, processor and deposits Store up the computer program that can be run in the memory and on the processor, which is characterized in that the processor executes It is realized when the computer program as described in any one of first aspect the step of atrial fibrillation detection method.
The fourth aspect of the embodiment of the present application provides a kind of computer readable storage medium, the computer-readable storage Media storage has computer program, and the atrial fibrillation as described in any one of first aspect is realized when the computer program is executed by processor The step of detection method.
Existing beneficial effect is the embodiment of the present application compared with prior art: the application utilizes related to adjacent R R interphase Heartbeat waveform so that the heartbeat waveform of interception can not only embody the morphological feature of electrocardiogram, but also also reflect between RR The changing rule of phase, thus can reflect the movable correlation properties of atrium and ventricle simultaneously;Using continuous wavelet transform to heartbeat Waveform processing obtains time-frequency spectrum tensor, can significantly more embody signal characteristic compared to one-dimensional electrocardiosignal;Using depth Convolutional neural networks carry out feature learning and classification to heartbeat waveform time-frequency spectrum tensor, avoid conventional method in feature extraction Workload and one-sidedness, for new type training sample have stronger adaptability, thus facilitate promoted nicety of grading.
Detailed description of the invention
It in order to more clearly explain the technical solutions in the embodiments of the present application, below will be to embodiment or description of the prior art Needed in attached drawing be briefly described, it should be apparent that, the accompanying drawings in the following description is only some of the application Embodiment for those of ordinary skill in the art without any creative labor, can also be according to these Attached drawing obtains other attached drawings.
Fig. 1 is the implementation process schematic diagram of atrial fibrillation detection method provided by the embodiments of the present application;
Fig. 2 is a kind of extraction provided by the embodiments of the present application heartbeat waveform schematic diagram relevant to RR interphase;
Fig. 3 is heartbeat waveform provided by the embodiments of the present application and continuous wavelet transform effect diagram;
Fig. 4 is the deep neural network structural schematic diagram that the embodiment of the present application uses;
Fig. 5 is the schematic diagram of atrial fibrillation detection device provided by the embodiments of the present application;
Fig. 6 is the schematic diagram of atrial fibrillation detection device provided by the embodiments of the present application.
Specific embodiment
In being described below, for illustration and not for limitation, the tool of such as particular system structure, technology etc is proposed Body details, so as to provide a thorough understanding of the present application embodiment.However, it will be clear to one skilled in the art that there is no these specific The application also may be implemented in the other embodiments of details.In other situations, it omits to well-known system, device, electricity The detailed description of road and method, so as not to obscure the description of the present application with unnecessary details.
In order to illustrate technical solution described herein, the following is a description of specific embodiments.
It is as shown in Figure 1 the implementation process schematic diagram of atrial fibrillation detection method described in the embodiment of the present application, details are as follows:
In step s101, heartbeat waveform relevant to RR interphase is extracted;
Specifically, the step of extraction heartbeat waveform relevant to RR interphase, may include:
1011, it can use the R wave wave crest in Pan's Tompkins Pan-Tompkins algorithm detection signal.If signal heads There is the huge spike for being significantly higher than normal R wave wave crest in portion, then will lead to subsequent wave crest can not be detected.It is asked to solve this Topic, the R wave wave crest number that can be will test is compared with scheduled a certain threshold value, if it is greater than or equal to this threshold value, Then show to detect successfully;If it is less than this threshold value, then show to receive the interference of head spike, then the starting point that will test to After put off a distance and repeat above-mentioned detection and judgement, until the R wave wave crest number detected reaches threshold value, or detection rises Point is postponed to signal end.
1012, according to R wave crest location, intercept heartbeat waveform list.For detecting i-th heartbeat in a bars, Its waveform initial position (Si) and final position (Ei) calculation formula it is as follows:
Wherein, Ri indicates the position (sampled point) of i-th of the R wave wave crest detected in the signal, and the value range of i is 2 It is the R wave wave crest sum detected to N-1, N.
It follows that the range of heartbeat waveform is determined by the numerical value of two RR interphases adjacent thereto.If previous RR Interphase is less than the latter RR interphase, then the position of R wave wave crest will be located at its preceding 1/3 part in the heartbeat waveform;Conversely, then R It the position of wave wave crest will be positioned at thereafter 1/3 part.If the numerical value of two RR interphases is equal, R wave wave crest is located at heartbeat wave On first 1/3 cut-point of shape.Therefore, which can reflect the change information of RR interphase in signal. It is as shown in Figure 2 that heartbeat waveform intercepts effect.
Certainly, as in the application preferably a kind of embodiment, in the step for extracting heartbeat waveform relevant to RR interphase Before rapid, it can also include the steps that being filtered electrocardiosignal, specifically include:
1001, signal is smoothed using rolling average counting method, removes the baseline drift letter in electrocardiosignal Number;
1002, utilize the noise in soft-threshold Wavelet noise-eliminating method removal electrocardiosignal.
Wherein, using in the baseline drift signal in method of moving average removal electrocardiosignal, it is 0.5 second that floating window, which can be used, Rolling average counting method signal be smoothed.Then, the signal after subtracting smoothing processing with original signal is removed The signal of baseline drift.
It can use the noise in soft-threshold Wavelet noise-eliminating method removal electrocardiosignal, the wavelet basis function used can be Sym8 (small wave system's small echo of serial number 8), the number of plies of decomposition are 5 layers.
By the baseline drift in removal electrocardiosignal, and use making an uproar in Wavelet noise-eliminating method removal electrocardiosignal Sound, available smooth electrocardiosignal.
In step s 102, continuous wavelet transform is carried out to the heartbeat waveform, reconstructs the time-frequency spectrum tensor of heartbeat waveform;
Specifically, can use the two-dimentional time-frequency spectrum that continuous wavelet transform formula obtains each jete waveform, wavelet transformation Formula is as follows:
Wherein, a and b is respectively scale factor and shift factor, and f (t) is the signal of output, and Ψ is wavelet basis function.Two Signal characteristic may preferably be reflected compared to 1 dimensional signal by tieing up time-frequency spectrum.Heartbeat waveform and continuous wavelet transform as shown in Figure 3 Effect diagram.
It, can be by acquisition in order to reduce time-frequency spectrum size to reduce the calculation amount of model training process and EMS memory occupation amount Time-frequency spectrum zooms to uniform sizes, such as 64 × 64.
Furthermore it is also possible to the time-frequency spectrum of continuous multiple heartbeat waveforms is superposed to a three-dimensional tensor in sequence, than The time-frequency spectrum of continuous 5 heartbeat waveforms is such as superposed to a three-dimensional tensor in sequence.Three of them dimension can be successively frequency Rate, time and heart sequence.Using such tensor as the input of subsequent classifier, it can detecte the tensor and correspond to time interval Inside whether atrial fibrillation has occurred.
In step s 103, by the depth convolutional neural networks of training completion to the time-frequency spectrum system structure of heartbeat waveform Feature learning and classification are carried out, the testing result of the heartbeat waveform is obtained.
Specifically, deep neural network provided by the embodiment of the present application, as shown in figure 4, it may include by 4 layers of convolution The tagsort part that the characteristic extraction part and 2 layers of full articulamentum that neural network is constituted are constituted, network structure can be such as figures Shown in 4.Each convolutional layer can respectively include 32 convolution kernels, and the convolution kernel size of the first two convolutional layer can be 10 × 10, the The convolution kernel size of three convolutional layers can be 8 × 8, and the convolution kernel size of the 4th convolutional layer can be 4 × 4;2nd and the 3rd Between convolutional layer, comprising a maximum pond layer between the 4th convolutional layer and the 1st full articulamentum (it is 2 × 2 that pondization, which reduces multiple) With one Dropout layers (loss ratio 0.2);1st full articulamentum includes 256 neurons, and the second full articulamentum includes 1 mind Through member.Activation primitive after each convolutional layer uses ReLu function, and the activation primitive of the second full articulamentum is sigmoid function (S Shape growth curve).The objective function of model training is to intersect entropy function, and formula is as follows:
Wherein, m is the sample number in training set, and x is the input data of sample, and y is sample labeling, and θ is model parameter.Mould Type training can use Stochastic Gradient Descent (stochastic gradient descent) optimization method, and learning rate can be 0.001, momentum can be 0.8, and weight decaying (Weight Decay) rate can be 10-6.The neural network model utilizes Keras It is realized and is trained based on TensorFlow (tensor stream) engine.
Trained and test data may come from MIT-BIH atrial fibrillation data set.The data set is dedicated for verifying atrial fibrillation inspection The performance of method of determining and calculating, the main electrocardiogram (ECG) data acquired from atrial fibrillation patient and normal person including 25 about 10 small durations, Sample rate is 250Hz.Wherein, " 00735 " and " 03665 " two data is due to lacking original ECG data thus not adopted With " 04936 " and " 05091 " two data is not also used due to the mistake existed on mark.Remaining every electrocardiographic recording Comprising the data acquired from two leads, it only used the data of wherein the first lead during realization of the invention.Instruction Practice collection and be taken from different electrocardiographic recordings from ecg wave form time-frequency spectrum tensor used in test set, to avoid model for few Number case generates over-fitting.The performance of this method by its enterprising having sexual intercourse of test set quiver detection sensibility (Se) and spy Anisotropic (Sp) is evaluated, and calculation formula is as follows:
Wherein, TP indicates that atrial fibrillation just examines sample number, and TN indicates that non-atrial fibrillation just examines sample number, and FP indicates atrial fibrillation erroneous detection sample Number, FN indicate non-atrial fibrillation erroneous detection sample number.Test result shows that the sensibility of herein described atrial fibrillation detection method is 99.41%, specificity is 98.91%.
It should be understood that the size of the serial number of each step is not meant that the order of the execution order in above-described embodiment, each process Execution sequence should be determined by its function and internal logic, the implementation process without coping with the embodiment of the present application constitutes any limit It is fixed.
Fig. 5 is a kind of structural schematic diagram of atrial fibrillation detection device provided by the embodiments of the present application, and details are as follows:
The atrial fibrillation detection device, comprising:
Heartbeat waveform extraction unit 501, for extracting heartbeat waveform relevant to RR interphase;
Time-frequency spectrum tensor reconfiguration unit 502 reconstructs heartbeat waveform for carrying out continuous wavelet transform to the heartbeat waveform Time-frequency spectrum tensor;
Learning classification unit 503, for the depth convolutional neural networks by training completion to the time-frequency spectrum of heartbeat waveform System structure carries out feature learning and classification, obtains the testing result of the heartbeat waveform.
Preferably, the heartbeat waveform extraction unit includes:
Wave crest detection sub-unit, for detecting the R wave in electrocardiosignal by Pan's Tompkins Pan-Tompkins algorithm Wave crest;
Waveform list interception unit, for intercepting heartbeat waveform list according to R wave crest location.
Preferably, the time-frequency spectrum tensor reconfiguration unit includes:
Subelement is converted, for utilizing continuous wavelet transform formula
The two-dimentional time-frequency spectrum of each heartbeat waveform is obtained, In, a and b are respectively scale factor and shift factor, and f (t) is the signal of output, and Ψ is wavelet basis function;
Subelement is scaled, for the time-frequency spectrum of acquisition to be zoomed to uniform sizes;
It is superimposed subelement, for the time-frequency spectrum of continuous multiple heartbeat waveforms to be superposed to a three-dimensional tensor in order, Three dimensions are followed successively by frequency, time and heart sequence.
Atrial fibrillation detection device described in Fig. 5, it is corresponding with atrial fibrillation detection method described in Fig. 1.
Fig. 6 is the schematic diagram for the atrial fibrillation detection device that one embodiment of the application provides.As shown in fig. 6, the room of the embodiment The detection device 6 that quivers includes: processor 60, memory 61 and is stored in the memory 61 and can be on the processor 60 The computer program 62 of operation, such as atrial fibrillation detect program.The processor 60 is realized when executing the computer program 62 State the step in each atrial fibrillation detection method embodiment, such as step 101 shown in FIG. 1 is to 103.Alternatively, the processor 60 The function of each module/unit in above-mentioned each Installation practice, such as module shown in Fig. 5 are realized when executing the computer program 62 501 to 503 function.
Illustratively, the computer program 62 can be divided into one or more module/units, it is one or Multiple module/units are stored in the memory 61, and are executed by the processor 60, to complete the application.Described one A or multiple module/units can be the series of computation machine program instruction section that can complete specific function, which is used for Implementation procedure of the computer program 62 in the atrial fibrillation detection device 6 is described.For example, the computer program 62 can be with It is divided into heartbeat waveform extraction unit, time-frequency spectrum tensor reconfiguration unit and learning classification unit, each unit concrete function is as follows:
Heartbeat waveform extraction unit, for extracting heartbeat waveform relevant to RR interphase;
Time-frequency spectrum tensor reconfiguration unit reconstructs heartbeat waveform for carrying out continuous wavelet transform to the heartbeat waveform Time-frequency spectrum tensor;
Learning classification unit, for the depth convolutional neural networks by training completion to the time-frequency spectra system of heartbeat waveform Structure carries out feature learning and classification, obtains the testing result of the heartbeat waveform.
The atrial fibrillation detection device 6 can be the calculating such as desktop PC, notebook, palm PC and cloud server Equipment.The atrial fibrillation detection device may include, but be not limited only to, processor 60, memory 61.Those skilled in the art can manage Solution, Fig. 6 is only the example of atrial fibrillation detection device 6, does not constitute the restriction to atrial fibrillation detection device 6, may include than diagram More or fewer components perhaps combine certain components or different components, such as the atrial fibrillation detection device can also wrap Include input-output equipment, network access equipment, bus etc..
Alleged processor 60 can be central processing unit (Central Processing Unit, CPU), can also be Other general processors, digital signal processor (Digital Signal Processor, DSP), specific integrated circuit (Application Specific Integrated Circuit, ASIC), ready-made programmable gate array (Field- Programmable Gate Array, FPGA) either other programmable logic device, discrete gate or transistor logic, Discrete hardware components etc..General processor can be microprocessor or the processor is also possible to any conventional processor Deng.
The memory 61 can be the internal storage unit of the atrial fibrillation detection device 6, such as atrial fibrillation detection device 6 Hard disk or memory.The memory 61 is also possible to the External memory equipment of the atrial fibrillation detection device 6, such as atrial fibrillation inspection The plug-in type hard disk being equipped on measurement equipment 6, intelligent memory card (Smart Media Card, SMC), secure digital (Secure Digital, SD) card, flash card (Flash Card) etc..Further, the memory 61 can also both include the atrial fibrillation The internal storage unit of detection device 6 also includes External memory equipment.The memory 61 is for storing the computer program And other programs and data needed for the atrial fibrillation detection device.The memory 61 can be also used for temporarily storing Output or the data that will be exported.
It is apparent to those skilled in the art that for convenience of description and succinctly, only with above-mentioned each function Can unit, module division progress for example, in practical application, can according to need and by above-mentioned function distribution by different Functional unit, module are completed, i.e., the internal structure of described device is divided into different functional unit or module, more than completing The all or part of function of description.Each functional unit in embodiment, module can integrate in one processing unit, can also To be that each unit physically exists alone, can also be integrated in one unit with two or more units, it is above-mentioned integrated Unit both can take the form of hardware realization, can also realize in the form of software functional units.In addition, each function list Member, the specific name of module are also only for convenience of distinguishing each other, the protection scope being not intended to limit this application.Above system The specific work process of middle unit, module, can refer to corresponding processes in the foregoing method embodiment, and details are not described herein.
In the above-described embodiments, it all emphasizes particularly on different fields to the description of each embodiment, is not described in detail or remembers in some embodiment The part of load may refer to the associated description of other embodiments.
Those of ordinary skill in the art may be aware that list described in conjunction with the examples disclosed in the embodiments of the present disclosure Member and algorithm steps can be realized with the combination of electronic hardware or computer software and electronic hardware.These functions are actually It is implemented in hardware or software, the specific application and design constraint depending on technical solution.Professional technician Each specific application can be used different methods to achieve the described function, but this realization is it is not considered that exceed Scope of the present application.
In embodiment provided herein, it should be understood that disclosed device/terminal device and method, it can be with It realizes by another way.For example, device described above/terminal device embodiment is only schematical, for example, institute The division of module or unit is stated, only a kind of logical function partition, there may be another division manner in actual implementation, such as Multiple units or components can be combined or can be integrated into another system, or some features can be ignored or not executed.Separately A bit, shown or discussed mutual coupling or direct-coupling or communication connection can be through some interfaces, device Or the INDIRECT COUPLING or communication connection of unit, it can be electrical property, mechanical or other forms.
The unit as illustrated by the separation member may or may not be physically separated, aobvious as unit The component shown may or may not be physical unit, it can and it is in one place, or may be distributed over multiple In network unit.It can select some or all of unit therein according to the actual needs to realize the mesh of this embodiment scheme 's.
It, can also be in addition, each functional unit in each embodiment of the application can integrate in one processing unit It is that each unit physically exists alone, can also be integrated in one unit with two or more units.Above-mentioned integrated list Member both can take the form of hardware realization, can also realize in the form of software functional units.
If the integrated module/unit be realized in the form of SFU software functional unit and as independent product sale or In use, can store in a computer readable storage medium.Based on this understanding, the application realizes above-mentioned implementation All or part of the process in example method, can also instruct relevant hardware to complete, the meter by computer program Calculation machine program can be stored in a computer readable storage medium, the computer program when being executed by processor, it can be achieved that on The step of stating each embodiment of the method.Wherein, the computer program includes computer program code, the computer program Code can be source code form, object identification code form, executable file or certain intermediate forms etc..Computer-readable Jie Matter may include: can carry the computer program code any entity or device, recording medium, USB flash disk, mobile hard disk, Magnetic disk, CD, computer storage, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), electric carrier signal, telecommunication signal and software distribution medium etc..It should be noted that described The content that computer-readable medium includes can carry out increasing appropriate according to the requirement made laws in jurisdiction with patent practice Subtract, such as in certain jurisdictions, according to legislation and patent practice, computer-readable medium do not include be electric carrier signal and Telecommunication signal.
Embodiment described above is only to illustrate the technical solution of the application, rather than its limitations;Although referring to aforementioned reality Example is applied the application is described in detail, those skilled in the art should understand that: it still can be to aforementioned each Technical solution documented by embodiment is modified or equivalent replacement of some of the technical features;And these are modified Or replacement, the spirit and scope of each embodiment technical solution of the application that it does not separate the essence of the corresponding technical solution should all Comprising within the scope of protection of this application.

Claims (10)

1. a kind of atrial fibrillation detection method, which is characterized in that the atrial fibrillation detection method includes:
Extract heartbeat waveform relevant to RR interphase;
Continuous wavelet transform is carried out to the heartbeat waveform, reconstructs the time-frequency spectrum tensor of heartbeat waveform;
The depth convolutional neural networks completed by training carry out feature learning to the time-frequency spectrum system structure of heartbeat waveform and divide Class obtains the testing result of the heartbeat waveform.
2. atrial fibrillation detection method according to claim 1, which is characterized in that described to extract heartbeat wave relevant to RR interphase The step of shape includes:
The R wave wave crest in electrocardiosignal is detected by Pan's Tompkins Pan-Tompkins algorithm;
According to R wave crest location, heartbeat waveform list is intercepted.
3. atrial fibrillation detection method according to claim 2, which is characterized in that it is described according to R wave crest location, intercept heartbeat In the step of waveform list, for i-th heartbeat, the initial position (S of waveformi) and final position (Ei) calculation formula such as Under:
Ri indicates the position (sampled point) of i-th of the R wave wave crest detected in the signal, and the value range of i is 2 to N-1, and N is The R wave wave crest sum detected.
4. atrial fibrillation detection method according to claim 1, which is characterized in that described continuous to heartbeat waveform progress small Wave conversion, the step of reconstructing the time-frequency spectrum tensor of heartbeat waveform include:
Utilize continuous wavelet transform formulaObtain each heartbeat waveform Two-dimentional time-frequency spectrum, wherein a and b is respectively scale factor and shift factor, and f (t) is the signal of output, and Ψ is wavelet basis letter Number;
The time-frequency spectrum of acquisition is zoomed into uniform sizes;
The time-frequency spectrum of continuous multiple heartbeat waveforms is superposed to a three-dimensional tensor in order, three of them dimension be followed successively by frequency, Time and heart sequence.
5. atrial fibrillation detection method according to claim 1, which is characterized in that extract heartbeat relevant to RR interphase described Before the step of waveform, the method also includes:
Signal is smoothed using rolling average counting method, removes the baseline drift signal in electrocardiosignal;
Utilize the noise in soft-threshold Wavelet noise-eliminating method removal electrocardiosignal.
6. a kind of atrial fibrillation detection device, which is characterized in that the atrial fibrillation detection device includes:
Heartbeat waveform extraction unit, for extracting heartbeat waveform relevant to RR interphase;
Time-frequency spectrum tensor reconfiguration unit reconstructs the time-frequency of heartbeat waveform for carrying out continuous wavelet transform to the heartbeat waveform Spectrum tensor;
Learning classification unit, for the depth convolutional neural networks by training completion to the time-frequency spectrum system structure of heartbeat waveform Feature learning and classification are carried out, the testing result of the heartbeat waveform is obtained.
7. atrial fibrillation detection device according to claim 6, which is characterized in that the heartbeat waveform extraction unit includes:
Wave crest detection sub-unit, for detecting the R wave wave crest in electrocardiosignal by Pan's Tompkins Pan-Tompkins algorithm;
Waveform list interception unit, for intercepting heartbeat waveform list according to R wave crest location.
8. atrial fibrillation detection method according to claim 6, which is characterized in that the time-frequency spectrum tensor reconfiguration unit includes:
Subelement is converted, for utilizing continuous wavelet transform formula
Obtain the two-dimentional time-frequency spectrum of each heartbeat waveform, wherein a It is respectively scale factor and shift factor with b, f (t) is the signal of output, and Ψ is wavelet basis function;
Subelement is scaled, for the time-frequency spectrum of acquisition to be zoomed to uniform sizes;
It is superimposed subelement, for the time-frequency spectrum of continuous multiple heartbeat waveforms to be superposed to a three-dimensional tensor in order, three of them Dimension is followed successively by frequency, time and heart sequence.
9. a kind of atrial fibrillation detection device, including memory, processor and storage are in the memory and can be in the processing The computer program run on device, which is characterized in that the processor realizes such as claim 1 when executing the computer program The step of to any one of 5 atrial fibrillation detection method.
10. a kind of computer readable storage medium, the computer-readable recording medium storage has computer program, and feature exists In the step of realization atrial fibrillation detection method as described in any one of claim 1 to 5 when the computer program is executed by processor Suddenly.
CN201810580271.7A 2018-06-07 2018-06-07 Atrial fibrillation detection method, device and equipment Active CN109124620B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810580271.7A CN109124620B (en) 2018-06-07 2018-06-07 Atrial fibrillation detection method, device and equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810580271.7A CN109124620B (en) 2018-06-07 2018-06-07 Atrial fibrillation detection method, device and equipment

Publications (2)

Publication Number Publication Date
CN109124620A true CN109124620A (en) 2019-01-04
CN109124620B CN109124620B (en) 2022-03-25

Family

ID=64801976

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810580271.7A Active CN109124620B (en) 2018-06-07 2018-06-07 Atrial fibrillation detection method, device and equipment

Country Status (1)

Country Link
CN (1) CN109124620B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893118A (en) * 2019-03-05 2019-06-18 武汉大学 A kind of electrocardiosignal classification diagnosis method based on deep learning
CN110037683A (en) * 2019-04-01 2019-07-23 上海数创医疗科技有限公司 The improvement convolutional neural networks and its training method of rhythm of the heart type for identification
CN110141214A (en) * 2019-04-23 2019-08-20 首都师范大学 A kind of mask method of electrocardiogram identification and its application
CN110598549A (en) * 2019-08-07 2019-12-20 王满 Convolutional neural network information processing system based on cardiac function monitoring and training method
CN111053551A (en) * 2019-12-27 2020-04-24 深圳邦健生物医疗设备股份有限公司 RR interval electrocardio data distribution display method, device, computer equipment and medium
CN111436926A (en) * 2020-04-03 2020-07-24 山东省人工智能研究院 Atrial fibrillation signal detection method based on statistical characteristics and convolution cyclic neural network

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140128758A1 (en) * 2012-11-08 2014-05-08 Conner Daniel Cross Galloway Electrocardiogram signal detection
CN105320969A (en) * 2015-11-20 2016-02-10 北京理工大学 A heart rate variability feature classification method based on multi-scale Renyi entropy
CN105411565A (en) * 2015-11-20 2016-03-23 北京理工大学 Heart rate variability feature classification method based on generalized scale wavelet entropy
CN106691437A (en) * 2017-01-26 2017-05-24 浙江铭众科技有限公司 Fetal heart rate extraction method based on maternal electrocardiosignals
CN107203692A (en) * 2017-05-09 2017-09-26 哈尔滨工业大学(威海) The implementation method of atrial fibrillation detection based on depth convolutional neural networks
CN107595276A (en) * 2017-08-22 2018-01-19 南京易哈科技有限公司 A kind of atrial fibrillation detection method based on single lead electrocardiosignal time-frequency characteristics

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140128758A1 (en) * 2012-11-08 2014-05-08 Conner Daniel Cross Galloway Electrocardiogram signal detection
CN105320969A (en) * 2015-11-20 2016-02-10 北京理工大学 A heart rate variability feature classification method based on multi-scale Renyi entropy
CN105411565A (en) * 2015-11-20 2016-03-23 北京理工大学 Heart rate variability feature classification method based on generalized scale wavelet entropy
CN106691437A (en) * 2017-01-26 2017-05-24 浙江铭众科技有限公司 Fetal heart rate extraction method based on maternal electrocardiosignals
CN107203692A (en) * 2017-05-09 2017-09-26 哈尔滨工业大学(威海) The implementation method of atrial fibrillation detection based on depth convolutional neural networks
CN107595276A (en) * 2017-08-22 2018-01-19 南京易哈科技有限公司 A kind of atrial fibrillation detection method based on single lead electrocardiosignal time-frequency characteristics

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893118A (en) * 2019-03-05 2019-06-18 武汉大学 A kind of electrocardiosignal classification diagnosis method based on deep learning
CN110037683A (en) * 2019-04-01 2019-07-23 上海数创医疗科技有限公司 The improvement convolutional neural networks and its training method of rhythm of the heart type for identification
CN110141214A (en) * 2019-04-23 2019-08-20 首都师范大学 A kind of mask method of electrocardiogram identification and its application
CN110598549A (en) * 2019-08-07 2019-12-20 王满 Convolutional neural network information processing system based on cardiac function monitoring and training method
CN111053551A (en) * 2019-12-27 2020-04-24 深圳邦健生物医疗设备股份有限公司 RR interval electrocardio data distribution display method, device, computer equipment and medium
CN111053551B (en) * 2019-12-27 2021-09-03 深圳邦健生物医疗设备股份有限公司 RR interval electrocardio data distribution display method, device, computer equipment and medium
CN111436926A (en) * 2020-04-03 2020-07-24 山东省人工智能研究院 Atrial fibrillation signal detection method based on statistical characteristics and convolution cyclic neural network
CN111436926B (en) * 2020-04-03 2021-04-20 山东省人工智能研究院 Atrial fibrillation signal detection method based on statistical characteristics and convolution cyclic neural network

Also Published As

Publication number Publication date
CN109124620B (en) 2022-03-25

Similar Documents

Publication Publication Date Title
CN109171712B (en) Atrial fibrillation identification method, atrial fibrillation identification device, atrial fibrillation identification equipment and computer readable storage medium
CN109124620A (en) A kind of atrial fibrillation detection method, device and equipment
KR102451795B1 (en) ECG signal detection method
CN107822622B (en) Electrocardiogram diagnosis method and system based on deep convolutional neural network
Liu et al. Arrhythmia classification of LSTM autoencoder based on time series anomaly detection
CN109864736A (en) Processing method, device, terminal device and the medium of electrocardiosignal
CN111990989A (en) Electrocardiosignal identification method based on generation countermeasure and convolution cyclic network
CN103815897B (en) Electrocardiogram characteristic extraction method
CN110619322A (en) Multi-lead electrocardio abnormal signal identification method and system based on multi-flow convolution cyclic neural network
CN105726018A (en) Automatic atrial fibrillation detection method irrelevant to RR interphase
CN108968941A (en) A kind of arrhythmia detection method, apparatus and terminal
CN108158578A (en) Noise segments recognition methods, ECG signal processing method and processing device
CN109077714B (en) Signal identification method, device, equipment and storage medium
CN106108880B (en) Automatic heart beat identification method and system
CN104840186A (en) Evaluation method of autonomic nervous function of patient suffering from CHF (Congestive Heart-Failure)
Li et al. Ventricular ectopic beat detection using a wavelet transform and a convolutional neural network
CN109948396A (en) A kind of beat classification method, beat classification device and electronic equipment
CN110367936B (en) Electrocardiosignal detection method and device
CN110367968B (en) Right bundle branch retardation detection method, device, equipment and storage medium
CN108509823A (en) The detection method and device of QRS complex
CN108742697A (en) Cardiechema signals sorting technique and terminal device
CN110464333A (en) A kind of storage method and device of ECG data
Rohmantri et al. Arrhythmia classification using 2D convolutional neural network
CN109044348A (en) atrial fibrillation detection device and storage medium
CN109044340B (en) Electrocardiogram data classification method and device, electronic equipment and storage medium

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CP01 Change in the name or title of a patent holder
CP01 Change in the name or title of a patent holder

Address after: 518000 Factory buildings and dormitories in Longkou Industrial Park, Gongye San Road, Pingdi Gaoqiao Industrial Park, Longgang District, Shenzhen City, Guangdong Province

Patentee after: SPACENTER SPACE SCIENCE AND TECHNOLOGY INSTITUTE

Address before: 518000 Factory buildings and dormitories in Longkou Industrial Park, Gongye San Road, Pingdi Gaoqiao Industrial Park, Longgang District, Shenzhen City, Guangdong Province

Patentee before: SPACE INSTITUTE OF SOUTHERN CHINA (SHENZHEN)

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20231013

Address after: 518172, 6th Floor, Building 2, Longkou Industrial Park, Gongye San Road, Gaoqiao Industrial Park, Pingdi Street, Longgang District, Shenzhen City, Guangdong Province

Patentee after: Shenzhen Green Star Space Technology Co.,Ltd.

Address before: 518000 Factory buildings and dormitories in Longkou Industrial Park, Gongye San Road, Pingdi Gaoqiao Industrial Park, Longgang District, Shenzhen City, Guangdong Province

Patentee before: SPACENTER SPACE SCIENCE AND TECHNOLOGY INSTITUTE