CN109123442A - A kind of preparation method of ox marrow piece - Google Patents
A kind of preparation method of ox marrow piece Download PDFInfo
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- CN109123442A CN109123442A CN201810863478.5A CN201810863478A CN109123442A CN 109123442 A CN109123442 A CN 109123442A CN 201810863478 A CN201810863478 A CN 201810863478A CN 109123442 A CN109123442 A CN 109123442A
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- marrow
- composite phospholipid
- cephalin
- filtrate
- phospholipid
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- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 150000003904 phospholipids Chemical class 0.000 claims abstract description 151
- 239000002131 composite material Substances 0.000 claims abstract description 149
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims abstract description 82
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 56
- 239000000706 filtrate Substances 0.000 claims abstract description 56
- 239000000787 lecithin Substances 0.000 claims abstract description 56
- 229940067606 lecithin Drugs 0.000 claims abstract description 56
- 235000010445 lecithin Nutrition 0.000 claims abstract description 56
- CFWRDBDJAOHXSH-SECBINFHSA-N 2-azaniumylethyl [(2r)-2,3-diacetyloxypropyl] phosphate Chemical compound CC(=O)OC[C@@H](OC(C)=O)COP(O)(=O)OCCN CFWRDBDJAOHXSH-SECBINFHSA-N 0.000 claims abstract description 55
- 239000000284 extract Substances 0.000 claims abstract description 49
- 239000007788 liquid Substances 0.000 claims abstract description 43
- 239000003208 petroleum Substances 0.000 claims abstract description 41
- 238000010438 heat treatment Methods 0.000 claims abstract description 34
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims abstract description 32
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 30
- 150000001875 compounds Chemical class 0.000 claims abstract description 30
- 210000004556 brain Anatomy 0.000 claims abstract description 29
- 239000012043 crude product Substances 0.000 claims abstract description 29
- 210000000278 spinal cord Anatomy 0.000 claims abstract description 28
- 229960000935 dehydrated alcohol Drugs 0.000 claims abstract description 26
- 239000012065 filter cake Substances 0.000 claims abstract description 26
- 239000000047 product Substances 0.000 claims abstract description 18
- 238000000926 separation method Methods 0.000 claims abstract description 18
- 238000001914 filtration Methods 0.000 claims abstract description 13
- 238000007654 immersion Methods 0.000 claims abstract description 13
- 238000002156 mixing Methods 0.000 claims abstract description 4
- 239000000843 powder Substances 0.000 claims description 88
- 229920002774 Maltodextrin Polymers 0.000 claims description 29
- 239000005913 Maltodextrin Substances 0.000 claims description 29
- 229940035034 maltodextrin Drugs 0.000 claims description 29
- 108010073771 Soybean Proteins Proteins 0.000 claims description 27
- 235000019710 soybean protein Nutrition 0.000 claims description 27
- 210000000988 bone and bone Anatomy 0.000 claims description 25
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 25
- 102000008186 Collagen Human genes 0.000 claims description 24
- 108010035532 Collagen Proteins 0.000 claims description 24
- 235000013336 milk Nutrition 0.000 claims description 24
- 239000008267 milk Substances 0.000 claims description 24
- 210000004080 milk Anatomy 0.000 claims description 24
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 23
- 230000008014 freezing Effects 0.000 claims description 14
- 238000007710 freezing Methods 0.000 claims description 14
- 238000001291 vacuum drying Methods 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 235000020985 whole grains Nutrition 0.000 claims description 12
- 238000005469 granulation Methods 0.000 claims description 11
- 230000003179 granulation Effects 0.000 claims description 11
- WHGYBXFWUBPSRW-UHFFFAOYSA-N Cycloheptaamylose Natural products O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO WHGYBXFWUBPSRW-UHFFFAOYSA-N 0.000 claims description 8
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 8
- 229960004756 ethanol Drugs 0.000 claims description 2
- 235000019441 ethanol Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 5
- 229920000858 Cyclodextrin Polymers 0.000 description 7
- 238000000605 extraction Methods 0.000 description 7
- 244000068988 Glycine max Species 0.000 description 5
- 235000010469 Glycine max Nutrition 0.000 description 5
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 241000282817 Bovidae Species 0.000 description 1
- 241000283698 Bubalus Species 0.000 description 1
- 241000030939 Bubalus bubalis Species 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000002639 bone cement Substances 0.000 description 1
- 210000004720 cerebrum Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
- A23L13/20—Meat products; Meat meal; Preparation or treatment thereof from offal, e.g. rinds, skins, marrow, tripes, feet, ears or snouts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to ox marrow product technique fields, propose a kind of preparation method of ox marrow piece, including a) taking brains, marrow and spinal cord that acetone is added after mixing according to the quality proportioning of 5:0.8-1.2:4.5-5.5, impregnate isolated compound crude product；B) the compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake, the cephalin composite phospholipid filtrate heating obtains cephalin composite phospholipid after isolating petroleum ether, it is added after the filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion, the lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, and the cephalin composite phospholipid and the lecithin composite phospholipid are mixed to get composite phospholipid liquid.Through the above technical solutions, solve the problems, such as the prior art lack can it is used as needed and keep phospholipid activity ox marrow product.
Description
Technical field
The invention belongs to ox marrow product technique fields, are related to a kind of preparation method of ox marrow piece.
Background technique
Ox marrow, Chinese medicine name.For Bovidae open country bovine animals ox Bos taurus domesticus Gmelin or Bubalus
The marrow of animal buffalo Bubalus bubalis Linnaeus.Throughout the whole nation.With enriching blood and replenishing vital essence, quench the thirst, stop blooding, stop-band it
Effect.It is usually used in essence and blood loss, consumptive disease is thin thin, it quenches one's thirst, hematemesis, hematochezia, metrorrhagia and metrostaxis, leukorrhagia.
The nutritional ingredient of ox marrow to the benefit of human body it is clear that still ox marrow needed during edible it is fresh take,
Fresh food is not able to satisfy the increasingly busy rhythm of life of modern, because the invention one kind can be used as needed, and does not lose phosphorus
The active ox marrow product of rouge effective component or necessary.
Summary of the invention
The present invention proposes a kind of preparation method of ox marrow piece, solve lack in the prior art can it is used as needed and keep
The problem of ox marrow product of phospholipid activity.
The technical scheme of the present invention is realized as follows:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) take brains, marrow and spinal cord that acetone is added after mixing according to the quality proportioning of 5:0.8-1.2:4.5-5.5,
Impregnate isolated compound crude product；
B) the compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter
Cake, the cephalin composite phospholipid filtrate heating obtain cephalin composite phospholipid after isolating petroleum ether,
It is added after the filter cake is isolated petroleum ether into dehydrated alcohol, the filter of lecithin composite phospholipid is obtained by filtration in immersion
Liquid, the lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by the brain phosphorus
Rouge composite phospholipid and the lecithin composite phospholipid are mixed to get composite phospholipid liquid；
C) the composite phospholipid liquid and cycloheptaamylose or soybean protein isolate-maltodextrin mixture are mixed, vacuum
It is dry, ox marrow extract powder is obtained,
D) it pelletized, done after being uniformly mixed the ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder
Product, the ox marrow extract powder, the yak marrow powder, the ox bone collagen protein peptides and the milk powder are made after dry and whole grain
Quality proportioning be 10-30:10-30:40-60:10.
Further, brains, marrow and spinal cord are cleaned up in the step a) with ionized water, is added after freezing chopping
Acetone impregnates isolated compound crude product.
Preferably, the quality proportioning of composite phospholipid liquid and cycloheptaamylose described in step c) is 1:2.8-3.2, described
Composite phospholipid liquid is 1:3.6-4.4 with the soybean protein isolate-maltodextrin mixture quality proportioning.
Preferably, cephalin composite phospholipid filtrate described in step b) separates petroleum ether, vacuum using vacuum oil bath heating
0.08 ± the 0.02MPa that is negative is spent, temperature is 50 ± 5 DEG C.
Preferably, lecithin composite phospholipid filtrate described in step b) uses the separating anhydrous ethyl alcohol of vacuum oil bath heating, very
Reciprocal of duty cycle is negative 0.08 ± 0.02MPa, and temperature is 50 ± 5 DEG C.
Preferably, vacuum drying vacuum degree is negative 0.09 ± 0.01MPa in step c), 55 ± 5 DEG C of heating temperature, dry
Time 4-5h.
It the working principle of the invention and has the beneficial effect that
1, the invention discloses a kind of preparation methods of ox marrow piece, first pass through the brains of ox, marrow, spinal cord organic molten
Agent extractive technique extracts the effective ingredients such as cephalin, lecithin and composite phospholipid therein, then the compound phosphorus to prevent extraction
Rouge is light-exposed, heat oxidation and lose activity elder generation and Bei Da-cyclodextrine or soybean protein isolate and maltodextrin is sufficiently mixed
Then Bei Da-cyclodextrine or soybean protein isolate and maltodextrin are sufficiently mixed packet using vacuum drying technique by embedding
Ox marrow extract powder is made in the composite phospholipid effective ingredient buried；Two, by ox marrow extract powder, yak marrow powder, bone glue
Former protein peptide powder is aided with the ox marrow function that the collocation of animal-derived food science is prepared into various series again after mixing according to a certain percentage
Food.The economical and effective physiological function for improving human body of ox marrow piece energy produced, has the effect of cerebrum tonifying, bone strengthening.
2, the present invention in brains, marrow and spinal cord are cleaned up with ionized water, freezing chopping after add acetone, soak
Steep isolated compound crude product, can increase the purity of composite phospholipid liquid, and by after the freezing chopping of brains, marrow and spinal cord into
Row extraction operation can increase extraction efficiency.
3, in the present invention when the quality proportioning for closing phosphatide liquid and cycloheptaamylose is 1:2.8-3.2, composite phospholipid liquid and big
When beans protein isolate-maltodextrin mixture quality proportioning is 1:3.6-4.4, the effective components such as phosphatide can be protected in ox marrow piece
Hold best activity.
4, cephalin composite phospholipid filtrate and lecithin composite phospholipid filtrate are carried out by the way of vacuum oil bath heating
Separation, can increase separation and Extraction effect, and can increase the efficiency of entire ox marrow piece preparation process.
Specific embodiment
In order to better understand the present invention, the present invention will be further described in detail below with reference to the embodiments.But this
The protection scope of invention is not limited to the range that embodiment is stated.Experimental method described in following embodiment and comparative examples,
It unless otherwise specified, is conventional method；The reagent and material commercially obtain unless otherwise specified.
Embodiment 1
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:0.8:4.5, by brains, marrow and spinal cord ionized water
It cleans up, adds acetone after freezing chopping, impregnate isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and cycloheptaamylose are mixed, vacuum drying obtains ox marrow extract powder, composite phospholipid liquid and β-
The quality proportioning of cyclodextrine is 1:2.8,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 10:10:
40:10.
Embodiment 2:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1:5, brains, marrow and spinal cord is cleaned with ionized water
Completely, acetone is added after freezing chopping, impregnates isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and cycloheptaamylose are mixed, vacuum drying obtains ox marrow extract powder, composite phospholipid liquid and β-
The quality proportioning of cyclodextrine is 1:3,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 20:20:
50:10.
Embodiment 3:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1.2:5.5, by brains, marrow and spinal cord ionized water
It cleans up, adds acetone after freezing chopping, impregnate isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and cycloheptaamylose are mixed, vacuum drying obtains ox marrow extract powder, composite phospholipid liquid and β-
The quality proportioning of cyclodextrine is 1:3.2,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 30:30:
60:10.
Embodiment 4:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:0.8:4.5, by brains, marrow and spinal cord ionized water
It cleans up, adds acetone after freezing chopping, impregnate isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and soybean protein isolate-maltodextrin mixture are mixed, vacuum drying, obtains the extraction of ox marrow
Powder, composite phospholipid liquid and soybean protein isolate-maltodextrin mixture quality proportioning are 1:3.6, soybean protein isolate-malt
The quality proportioning of soybean protein isolate and maltodextrin is 1:5 in cyclodextrin mixtures,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 10:10:
40:10.
Embodiment 5:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1:5, brains, marrow and spinal cord is cleaned with ionized water
Completely, acetone is added after freezing chopping, impregnates isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and soybean protein isolate-maltodextrin mixture are mixed, vacuum drying, obtains the extraction of ox marrow
Powder, composite phospholipid liquid and soybean protein isolate-maltodextrin mixture quality proportioning are 1:4, soybean protein isolate-malt paste
The quality proportioning of soybean protein isolate and maltodextrin is 1:1 in smart mixture,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 20:20:
50:10.
Embodiment 6:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1.2:5.5, by brains, marrow and spinal cord ionized water
It cleans up, adds acetone after freezing chopping, impregnate isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and soybean protein isolate-maltodextrin mixture are mixed, vacuum drying, obtains the extraction of ox marrow
Powder, composite phospholipid liquid and soybean protein isolate-maltodextrin mixture quality proportioning are 1:4.4, soybean protein isolate-malt
The quality proportioning of soybean protein isolate and maltodextrin is 5:1 in cyclodextrin mixtures,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 30:30:
60:10.
Embodiment 7:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1:5, brains, marrow and spinal cord is cleaned with ionized water
Completely, acetone is added after freezing chopping, impregnates isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
Cephalin composite phospholipid filter vacuum oil bath heating obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate progress vacuum oil bath heating isolates dehydrated alcohol and obtains lecithin composite phospholipid, and cephalin is answered
It closes phosphatide and lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and soybean protein isolate-maltodextrin mixture are mixed, vacuum drying, vacuum degree is negative
0.09MPa, heating temperature are 50-60 DEG C, and drying time 4-5 hour obtains ox marrow extract powder, composite phospholipid liquid and soybean separation
Albumen-maltodextrin mixture quality proportioning is 1:4, soybean protein isolate in soybean protein isolate-maltodextrin mixture
Quality proportioning with maltodextrin is 1:1,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 20:20:
50:10.
Comparative example 1:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1:5, brains, marrow and spinal cord is cleaned with ionized water
Completely, acetone is added after freezing chopping, impregnates isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and wheat flour are mixed, vacuum drying, obtains ox marrow extract powder, composite phospholipid liquid and soybean point
It is 1:4, soybean separation protein in soybean protein isolate-maltodextrin mixture from albumen-maltodextrin mixture quality proportioning
The white quality proportioning with maltodextrin is 1:1,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 20:20:
50:10.
Comparative example 2:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1:5, brains, marrow and spinal cord is cleaned with ionized water
Completely, acetone is added after freezing chopping, impregnates isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and soybean protein isolate are mixed, vacuum drying, obtain ox marrow extract powder, composite phospholipid liquid and
Soybean protein isolate-maltodextrin mixture quality proportioning is 1:4, soybean in soybean protein isolate-maltodextrin mixture
Protein isolate and the quality proportioning of maltodextrin are 1:1,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 20:20:
50:10.
Comparative example 3:
A kind of preparation method of ox marrow piece, comprising the following steps:
A) brains, marrow and spinal cord are taken according to the quality proportioning of 5:1:5, brains, marrow and spinal cord is cleaned with ionized water
Completely, acetone is added after freezing chopping, impregnates isolated compound crude product；
B) compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The heating of cephalin composite phospholipid filtrate obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
Lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, by cephalin composite phospholipid and
Lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) composite phospholipid liquid and maltodextrin are mixed, vacuum drying obtains ox marrow extract powder, composite phospholipid liquid and soybean
Protein isolate-maltodextrin mixture quality proportioning is 1:4, soybean separation in soybean protein isolate-maltodextrin mixture
The quality proportioning of albumen and maltodextrin is 1:1,
D) by ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
Be made product after whole grain, ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder quality proportioning be 20:20:
50:10.
Inventor cooperates with certain hospital, has chosen 150 low inferior healths of physical function from 2016.7-2017.12 and asks
The patient of topic, specific distribution are as follows:
A: physical examination is without exception but the continuous person 70 that catches a cold throughout the year, the age at 20-40 years old, wherein male 30, women
40, it is divided into 10 groups, every group of 7 people,
B: physical examination is without exception but the obvious low person 80 of memory, and wherein male 35, are divided into 10 groups, often by women 45
8 people of group,
By ox marrow piece obtained in above-described embodiment, after placing 3 months, above-mentioned patient is according to 2g/ piece, and 3 times/day, 2/
Secondary product rate is taken, and half a year in period, Indexes of Evaluation Effect is as follows,
It is that continuous half a year is ailing without flu that wherein A group, which cures index, and efficiency index is continuous 3 months ailing without flu, nothing
Imitating index is that flu frequency is constant,
B group: excellent, memory is obviously deducted a percentage,
Good: memory has promotion, but promotion is unobvious,
Difference: memory is without significant change.
Test result is as follows:
The above is merely preferred embodiments of the present invention, be not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (6)
1. a kind of preparation method of ox marrow piece, it is characterised in that: the following steps are included:
A) it takes brains, marrow and spinal cord that acetone is added after mixing according to the quality proportioning of 5:0.8-1.2:4.5-5.5, impregnates
Isolated compound crude product；
B) the compound crude product is added and extracts separation into petroleum ether, obtain cephalin composite phospholipid filtrate and filter cake,
The cephalin composite phospholipid filtrate heating obtains cephalin composite phospholipid after isolating petroleum ether,
It being added after the filter cake is isolated petroleum ether into dehydrated alcohol, lecithin composite phospholipid filtrate is obtained by filtration in immersion,
The lecithin composite phospholipid filtrate carries out heating and isolates dehydrated alcohol and obtain lecithin composite phospholipid, and the cephalin is answered
It closes phosphatide and the lecithin composite phospholipid is mixed to get composite phospholipid liquid；
C) the composite phospholipid liquid and cycloheptaamylose or soybean protein isolate-maltodextrin mixture are mixed, vacuum drying,
Ox marrow extract powder is obtained,
D) by the ox marrow extract powder, yak marrow powder, ox bone collagen protein peptides and milk powder be uniformly mixed after through granulation, drying and
After whole grain be made product, the ox marrow extract powder, the yak marrow powder, the ox bone collagen protein peptides and the milk powder matter
Amount proportion is 10-30:10-30:40-60:10.
2. a kind of preparation method of ox marrow piece according to claim 1, it is characterised in that: in the step a) by brains,
Marrow and spinal cord are cleaned up with ionized water, are added acetone after freezing chopping, are impregnated isolated compound crude product.
3. a kind of preparation method of ox marrow piece according to claim 1, it is characterised in that: composite phospholipid described in step c)
The quality proportioning of liquid and cycloheptaamylose is 1:2.8-3.2, and the composite phospholipid liquid and the soybean protein isolate-malt are pasted
The quality proportioning of smart mixture is 1:3.6-4.4.
4. a kind of preparation method of ox marrow piece according to claim 1, it is characterised in that: cephalin described in step b) is multiple
It closes phosphatide filtrate and petroleum ether is separated using vacuum oil bath heating, vacuum degree is negative 0.08 ± 0.02MPa, and temperature is 50 ± 5 DEG C.
5. a kind of preparation method of ox marrow piece according to claim 1, it is characterised in that: lecithin described in step b) is multiple
It closes phosphatide filtrate and uses the separating anhydrous ethyl alcohol of vacuum oil bath heating, vacuum degree is negative 0.08 ± 0.02MPa, and temperature is 50 ± 5 DEG C.
6. a kind of preparation method of ox marrow piece according to claim 1, it is characterised in that: vacuum drying true in step c)
Reciprocal of duty cycle is negative 0.09 ± 0.01MPa, and 55 ± 5 DEG C of heating temperature, drying time 4-5h.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113662147A (en) * | 2021-07-19 | 2021-11-19 | 辽宁生物时代健康食品有限公司 | Chinese yam and beef marrow powder and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103783545A (en) * | 2014-01-24 | 2014-05-14 | 徐州三髓生物科技有限公司 | Preparation method of three-marrow powder |
| CN105613789A (en) * | 2016-03-14 | 2016-06-01 | 广州金酮医疗科技有限公司 | High-fat and high-dietary-fiber composite animal and plant powdered oil and preparation method and application thereof |
| CN107712097A (en) * | 2017-10-16 | 2018-02-23 | 张海生 | The preparation method of almond -apricot almond oil micro-capsules |
-
2018
- 2018-08-01 CN CN201810863478.5A patent/CN109123442A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103783545A (en) * | 2014-01-24 | 2014-05-14 | 徐州三髓生物科技有限公司 | Preparation method of three-marrow powder |
| CN105613789A (en) * | 2016-03-14 | 2016-06-01 | 广州金酮医疗科技有限公司 | High-fat and high-dietary-fiber composite animal and plant powdered oil and preparation method and application thereof |
| CN107712097A (en) * | 2017-10-16 | 2018-02-23 | 张海生 | The preparation method of almond -apricot almond oil micro-capsules |
Non-Patent Citations (1)
| Title |
|---|
| 刘荣建，等: ""鹅肥肝中卵磷脂提取工艺研究"，刘荣建，等，第10-12页，河北工业科技，第21卷第2期", 《鹅肥肝中卵磷脂提取工艺研究》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113662147A (en) * | 2021-07-19 | 2021-11-19 | 辽宁生物时代健康食品有限公司 | Chinese yam and beef marrow powder and preparation method thereof |
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Application publication date: 20190104 |