CN109106868A - A kind of oral traditional Chinese medicine composition for treating hypertension - Google Patents
A kind of oral traditional Chinese medicine composition for treating hypertension Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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Abstract
The present invention discloses a kind of oral traditional Chinese medicine composition for treating hypertension, is grouped as by lower example group, the parts by weight of each component are as follows: corn stigma 30-50, radix cynanchi atrati 20-40, motherwort 30-50, Radix Achyranthis Bidentatae 10-30, pheretima 10-30, raw hawthorn 15-35, Prunella vulgaris 30-50, Rhizoma Chuanxiong 10-20, Semen Leonuri 10-30, pueraria lobata 15-30, keel 30-50, oyster 30-50, raw sophora bud 10-20, setose thistle 10-30.Above-mentioned Chinese medicine material cleaning, drying, is ground into a powder, 100-120 mesh of looking over so as to check, and various conventional internal dosage forms are made after disinfection.Such as: it these raw materials is ground into powder is uniformly mixed and powder is made takes after mixing it with water or be made the peroral dosage forms such as other water-bindered pills, honeyed bolus, capsule and pill, it is oral that decoction of medicinal ingredients can also be directly prepared into.Morning and evening sub-service contains 6 grams of crude drug every time, 3 courses for the treatment of is generally used in conjunction.It is an advantage of the invention that compatibility is reasonable, convenient to take, curative effect is reliable, has no toxic side effect, and visits 1 year no relapse.
Description
Technical field
The present invention relates to traditional Chinese medicine and pharmacy technical field, in particular to a kind of oral traditional Chinese medicine composition for treating hypertension.
Background technique
Hypertension is the most common cardiovascular disease in the world, is also the largest one of epidemic disease.Often with headache, dizziness, ear
Ring, extremity numbness etc. are main clinical manifestation.It is that blood lipid and cholesterol are excessively high that modern medicine, which thinks mostly, makes atherosclerosis,
Hemadostewnosis and vasopasm cause.Treatment mostly uses calm, loose smooth muscle, lipid-loweringing, diuresis etc..Chinese medicine thinks hypertension category
" dizziness " scope."Nei Jing" has " all wind trembling and dizziness come under liver ", it is seen that its interpretation of the cause, onset and process of an illness is resisted on " liver wind agitation " wind sun, then head of having a headache
It is dizzy;Interior wind attacks network, the deficiency of blood cannot flourish muscle then hemiplegia, blood network ailment said due to cold or exposure hinder numbness, then it is then apathetic to be unable to movement by brothers.At present
Whether the precedent that modern medicine or traditional Chinese medicine are all cured without conservative therapy.Through retrieval find useful ox sunset, hawthorn,
The compositions such as Prunella vulgaris, pueraria lobata, the sophora bud treat hypertension drug, are verified by clinical use, clinical efficacy is unsatisfactory.
Summary of the invention
The object of the invention is exactly to provide a kind of with advantages of perfect compatibility, nontoxic pair to overcome defects in the prior art
Effect, curative effect reliably treat the traditional Chinese medicine for oral administration of hypertension.
To achieve the goals above, the present invention adopts the following technical scheme that.
A kind of oral traditional Chinese medicine composition for treating hypertension, the medicinal material including following portions by weight proportion, corn stigma 30-
50, radix cynanchi atrati 20-40, motherwort 30-50, Radix Achyranthis Bidentatae 10-30, pheretima 10-30, raw hawthorn 15-35, Prunella vulgaris 30-50, Rhizoma Chuanxiong
10-20, Semen Leonuri 10-30, pueraria lobata 15-30, keel 30-50, oyster 30-50, raw sophora bud 10-20, setose thistle 10-30.
Above-mentioned medicinal material preparation method are as follows: by medicinal material cleaning, drying pulverization, cross 100-120 mesh, be made after disinfection various normal
Advise internal dosage form.Such as: it these raw materials is ground into powder is uniformly mixed and powder is made takes after mixing it with water or be made other water-bindered pills, honeyed bolus, capsule and pill
Equal peroral dosage forms, it is oral can also to be directly prepared into decoction of medicinal ingredients.Morning and evening sub-service contains 6 grams of crude drug every time, and January is as a treatment course, generally
3 courses for the treatment of are used in conjunction.
It is characteristic of the invention that traditional Chinese medicine for oral administration can cure hypertension, its advantage is that compatibility is reasonable, convenient to take, curative effect can
It leans on, has no toxic side effect, cure rate is high, visits 1 year no relapse.
Specific embodiment
Embodiment 1: corn stigma 40, radix cynanchi atrati 30, motherwort 40, Radix Achyranthis Bidentatae 25, pheretima 25, raw hawthorn 25, Prunella vulgaris 40, Pueraria lobota
Root 20, Rhizoma Chuanxiong 15, Semen Leonuri 20, keel 40, oyster 40, the raw sophora bud 15, setose thistle 15.
Above-mentioned medicinal material cleaning, drying is ground into a powder, 100-120 mesh is crossed, various conventional internal dosage forms are made after disinfection.
Such as: it these raw materials is ground into powder is uniformly mixed and powder is made takes after mixing it with water or be made the peroral dosage forms such as other water-bindered pills, honeyed bolus, capsule and pill,
It is oral that decoction of medicinal ingredients can also be directly prepared into.Morning and evening sub-service contains 6 grams of crude drug every time, without any reaction after this proportion medicine patient clothes, one
The moon is as a treatment course, examines clinical efficacy after 3 courses for the treatment of of taking medicine, and achieves more satisfied curative effect.It can be seen that corn stigma, radix cynanchi atrati, dragon
Bone, oyster, setose thistle play obvious action and key point of the invention in this compatibility.
1, general information.
Accept out-patient 60 for medical treatment, the age 35-85 years old, course of disease 1-10.
2, criterion of therapeutical effect.
It is treatment foundation according to " Chinese medical disease conventional treatment " Chinese medicine dizziness criterion of therapeutical effect.Effective: clinical symptoms, sign are bright
It is aobvious to improve;Diastolic pressure declines 10mmHg or more, though and reach normal range (NR) or diastolic pressure does not drop to normally, declined
20mmHg or more.Effective: Clinical symptom and sign take a favorable turn;Diastole drops not as good as 10mmHg, but have reached normal range (NR) or
Diastolic pressure declines (10-19mmHg) before relatively treating;Invalid: Clinical symptom and sign is not improved, or aggravate, blood pressure not up to
Upper standard.
3, treatment method: 60 patients are accepted in outpatient service for medical treatment, are randomly divided into treatment group 30, and control group 30.
Treatment results.
A treatment group takes 1 formula of implementation to contain 6 grams of crude drug every time, 3 courses for the treatment of are used in conjunction in 1 month course for the treatment of 2 times a day.It cures
It 22, improves 5, invalid 3.Cure rate is 73.3%, total effective rate 90.9%, invalid 10%.
The theory of traditional Chinese medical science and medication foundation of oral medicinal herb treatment hypertension.
Theory of traditional Chinese medical science foundation.
Chinese medicine thinks that the interpretation of the cause, onset and process of an illness of this disease is resisted on " liver wind agitation " wind sun, then head and dizzy;Interior wind attacks network, and the deficiency of blood cannot be flourish
Muscle, then at hemiplegia;Blood network ailment said due to cold or exposure hinders numbness, then brothers are unable to movement and apathetic;Deficient qi and blood must not on fill in brain, clearly
Key is hollow or hemostasis holds the turbid wind fire resistance of phlegm under the arm and then has a headache in brain key, dizziness.Treatment is when with calming the liver to stop the wind, blood circulation and channel invigorating, decompression is except dizzy
For method.It selects to apply calming the liver to stop the wind, disperse blood stasis and dredge collateral, blood circulation and channel invigorating, and it is in middle medical knowledge that decompression, which removes the capsule and pill of dizzy Chinese medicinal composition,
By the embodiment of medication specific under guidance.More embody the realistic meaning of theoretical direction clinic.
Medication foundation: corn stigma diuretic antihypertensive;Radix cynanchi atrati clearing away heat and promoting diuresis, antihypertensive diuretic;The detumescence of motherwort activating blood and promoting diuresis;Cherish ox
Sunset promoting blood circulation for regulating menstruation, ensuring proper downward flow of the blood;Pheretima calming wind and dredging collateral;Prunella vulgaris clears liver and improve vision detumescence;Rhizoma Chuanxiong, the decompression of Semen Leonuri promoting blood circulation by removing wind;
Keel, the calming the liver tranquilizing the mind of oyster;The sophora bud, setose thistle cooling blood and hemostasis dissipate the stasis of blood.All medicines share plays calming the liver to stop the wind, disperse blood stasis and dredge collateral altogether,
Blood circulation and channel invigorating, decompression remove the effect of dizzy.
Modern pharmacological research proves: we can hypertension and hyperlipemia, activating microcirculation and removing stasis medicinal adjusts blood operation, and can prevent high blood
The appearance of coronary heart disease and cerebral apoplexy caused by pressing.The Fang Zhongyong sophora bud, setose thistle hemostasis can prevent hypertensive patient in activating microcirculation and removing stasis medicinal, prevent
Thrombosis prevents rupture of blood vessel in brain caused by hypertension and cerebral apoplexy again, and we have a multifunctional effect, persistent,
Toxic side effect is not found.
Case 1: Zhang, male, 46 years old, Wuhe County Automobile Transportation Company driver, in March, 2012, dizziness headache, right upper extremity fiber crops
Meciless, the measuring blood pressure 160/105mmHg of wood, takes various depressor certainly, when it is light when weight, in August, 2014 comes to go to a doctor: measuring blood pressure 150/
102mmHg takes one month measuring blood pressure 140/90mmHg of the present invention, and following the service one month, measuring blood pressure, 135/88mmHg was visited 1 year
It does not recur.
Case 2: poplar, female, 58 years old, dizzy headache, 8 years medical histories of hypertension.In August, 2013 is medical, makees when dizzy low heavy
Make swollen, the vexed dry of flushing, two hands are numb, and it is unknown to take a variety of depressor certainly by measuring blood pressure 150/95mmHg.The clothes present invention 2 months,
Measuring blood pressure 130/80mmHg, all symptoms disappear, visits 2 years and does not recur.
Claims (2)
1. a kind of oral traditional Chinese medicine composition for treating hypertension, it is characterised in that be made of the medicinal material of following portions by weight ratio:
Corn stigma 30-50, radix cynanchi atrati 20-40, motherwort 30-50, Radix Achyranthis Bidentatae 10-30, pheretima 10-30, raw hawthorn 15-35, Prunella vulgaris 30-
50, Rhizoma Chuanxiong 10-20, Semen Leonuri 10-30, pueraria lobata 15-30, keel 30-50, oyster 30-50, raw sophora bud 10-20, setose thistle 10-30.
2. its feature of the oral traditional Chinese medicine composition for the treatment of hypertension according to claim 1, is grouped as, each group by lower example group
Parts by weight are as follows: corn stigma 40, radix cynanchi atrati 30, motherwort 40, Radix Achyranthis Bidentatae 25, pheretima 25, raw hawthorn 25, Prunella vulgaris 40, pueraria lobata 20,
Rhizoma Chuanxiong 15, Semen Leonuri 20, keel 40, oyster 40, the raw sophora bud 15, setose thistle 15.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102652795A (en) * | 2012-04-12 | 2012-09-05 | 王伟 | Traditional Chinese medicine extract for treating hypertension and preparation method of traditional Chinese medicine extract |
CN102698137A (en) * | 2012-06-21 | 2012-10-03 | 王杰 | Composition with blood pressure reducing function and preparation method of same |
RU2479315C1 (en) * | 2011-12-26 | 2013-04-20 | Федеральное государственное бюджетное учреждение "Научный центр проблем здоровья семьи и репродукции человека" Сибирского отделения Российской академии медицинских наук (ФГБУ "НЦ ПЗСРЧ") | Herbal tea for treating adolescents with labile arterial hypertension |
CN104524288A (en) * | 2014-12-25 | 2015-04-22 | 庞凤梅 | Traditional Chinese medicinal composition for treating hypertension |
-
2017
- 2017-06-23 CN CN201710489025.6A patent/CN109106868A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2479315C1 (en) * | 2011-12-26 | 2013-04-20 | Федеральное государственное бюджетное учреждение "Научный центр проблем здоровья семьи и репродукции человека" Сибирского отделения Российской академии медицинских наук (ФГБУ "НЦ ПЗСРЧ") | Herbal tea for treating adolescents with labile arterial hypertension |
CN102652795A (en) * | 2012-04-12 | 2012-09-05 | 王伟 | Traditional Chinese medicine extract for treating hypertension and preparation method of traditional Chinese medicine extract |
CN102698137A (en) * | 2012-06-21 | 2012-10-03 | 王杰 | Composition with blood pressure reducing function and preparation method of same |
CN104524288A (en) * | 2014-12-25 | 2015-04-22 | 庞凤梅 | Traditional Chinese medicinal composition for treating hypertension |
Non-Patent Citations (1)
Title |
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陈可冀等编: "《中西医结合研究丛书 心脑血管疾病研究》", 29 February 1988 * |
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