CN109106784A - A kind of anti-treating cervicitis, drug of cervical erosion and preparation method thereof - Google Patents

A kind of anti-treating cervicitis, drug of cervical erosion and preparation method thereof Download PDF

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Publication number
CN109106784A
CN109106784A CN201810926586.2A CN201810926586A CN109106784A CN 109106784 A CN109106784 A CN 109106784A CN 201810926586 A CN201810926586 A CN 201810926586A CN 109106784 A CN109106784 A CN 109106784A
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drug
cervical erosion
parts
myrrh
olibanum
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杨光禄
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Guangxi Chengyan Medical Technology Co Ltd
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Guangxi Chengyan Medical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Engineering & Computer Science (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of anti-treating cervicitis, the drug of cervical erosion and preparation method thereof.Pharmaceutical formulation of the present invention be using: kiss-me, Cortex Phellodendri, alum, myrrh, olibanum are formed as raw material proportioning, according to water decoct, concentration, calcining, crush, mixing preparation method paste is made, anti-treating cervicitis, cervical erosion are significant in efficacy.

Description

A kind of anti-treating cervicitis, drug of cervical erosion and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines more particularly to a kind of anti-treating cervicitis, the drug of cervical erosion and preparation method thereof.
Background technique
Cervicitis is one of women common disease, accounts for about 70 or so the percent of female gynecological disease, wherein acute Only account for less than 10, it is chronic in 70 or more percent development be cervical erosion.Cervicitis, cervical erosion China hair Sick rate is very high, falls ill in recent years in rising trend, seriously affects the physical and mental health of patient.
Treatment cervicitis, cervical erosion mainly treat two kinds with drug and physical method at present, and drug treatment includes Oral drugs and external suppository treatment, this respect drug is many, but can only all alleviate the state of an illness, cannot reach the effect of healing Fruit, so many cervical erosion can only select physical treatment regime, physiotherapy includes: leep knife (electric knife) uterine neck electric heating Ring operation, micro-wave therapeutic, carbon dioxide laser treatment, uterine neck liquid nitrogen freezing, the roasting, fulguration of electricity etc., but physiotherapy is cured Rate is extremely low and there are many side effects, and patient has fear when such as treating, and the neoplasm time is long, stadium decrustationis bleeding, Bu Nengsheng Educate, wound is difficult to restore, destroy muscular tissue structure, self immunity destroy it is serious, it is easy to recur, and to treatment HPV infection without Effect etc..It can be seen that there is clearly disadvantageous and defects for treatment method and therapeutic agent of the tradition to cervicitis, it would be highly desirable into One step is improved.
Therefore, actively anti-treating cervicitis improves WomanHealth level and promotes family social harmonious to prevention cervical lesions It is of great significance.
Summary of the invention
The object of the present invention is to provide a kind of new anti-treating cervicitis, the drug of cervical erosion and preparation method thereof, prevention and treatments Cervicitis, cervical erosion are significant in efficacy.
The present invention is achieved by the following technical scheme:
A kind of drug of anti-treating cervicitis, cervical erosion, it is characterised in that the weight proportion of various bulk pharmaceutical chemicals are as follows: 30 parts of Cortex Phellodendri- 40 parts, 15-25 parts of kiss-me, 15-25 parts of alum, 15-20 parts of myrrh, 3-8 parts of olibanum.
A kind of anti-treating cervicitis, cervical erosion drug preparation method, it is characterised in that prepare as follows:
(1) add 4-8 times of water to decoct a hour after selected Cortex Phellodendri, kiss-me coarse crushing in proportion, medical fluid contained after pulling the dregs of a decoction out, 4-8 times of water is added to decoct a hour filtering the filtered dregs of a decoction again, it is 1.15- that medical fluid twice is concentrated into specific gravity together 1.30, A is made;
(2) take ash that B is made after taking the alum calcining of proportion deal;
(3) myrrh, the olibanum of selected proportion deal crush at a temperature of 20-25 DEG C, and C is made;
(4) B, C are mixed into A, stir evenly and paste is made.
The alum calcination ash, myrrh, olibanum crushed 80-120 mesh.
Kiss-me, Cortex Phellodendri have curative effect in terms of extremely strong inhibiting effect, especially gynaecological imflammation splendid inflammation in side.Brave ear Grass has the title of the antibiotic of Chinese medicine, this mutual compatibility of two medicines, has clearing heat and detoxicating, anti-inflammatory disease and other effects.Myrrh, olibanum, which have, dispels The effect of necrotic tissue and promoting muscle growing, especially olibanum, mix myrrh, have the effect that an apt word added to clinch the point, effect of removing necrosis and promoting granulation of myrrh is made to reach splendid water It is flat, have the function that rotten to the corn face healing.Alum (aluminum potassium sulfate) is used as medicine after calcination with alumen in side, the content pole of aluminium Height, effect is fabulous in terms for the treatment of cervical erosion, especially has very strong inhibiting effect to HPV viruse.Drug of the invention Anti- treating cervicitis, cervical erosion are significant in efficacy.
Each herbal medicine medicinal peace in side, and lesion directly is acted on through epidermis, double to the curative effect of the disease, and without obvious Toxic side effect, it is one that the paste after patent medicine is weakly acidic, suitable with vaginal environment pH value, therefore will not destroy vaginal environment Curative effect is high, the good medicine having no toxic side effect.
Traditional Chinese medicine is multiplied and lived in my Chinese nation to be played the role of in thousands of years great, and the effect of Chinese medicine is not only So simple, mutual compatibility between special drug, interaction are seen in surface, some effects can not get across, this side's answers With with popularization, solve cervicitis, the incurable status of cervical erosion, filled up treat this field blank, thus it is possible to vary The existing therapeutic scheme of this disease, rescues vast patient from the serious illness, gives the great treatment confidence of doctor, together When also greatly reduce the burden of medical expense.
Specific embodiment
The following examples limit the present invention for the present invention will be described.
Embodiment 1
Weigh bulk pharmaceutical chemicals: Cortex Phellodendri 30 parts of kg, kiss-me 25kg, alum 20kg, myrrh 20kg, olibanum 3kg.
(1) add 6 times of water to decoct a hours after selected Cortex Phellodendri, kiss-me coarse crushing in proportion, medical fluid is contained after pulling the dregs of a decoction out It is good, then adding 6 times of water to decoct a hour filtering medical fluid twice is concentrated into specific gravity together the filtered dregs of a decoction is 1.15- 1.20, A is made.
(2) ash is taken after calcining alum, is crushed, and crosses 120 meshes, B is made.
(3) selected myrrh, olibanum are crushed into powder at a temperature of 20 DEG C, cross 80 meshes, C is made.
(4) B, C are mixed into stir evenly in A and paste is made.
Embodiment 2
Weigh bulk pharmaceutical chemicals: Cortex Phellodendri 38 parts of kg, kiss-me 15kg, alum 15kg, myrrh 16kg, olibanum 8kg.
(1) add 8 times of water to decoct a hours after selected Cortex Phellodendri, kiss-me coarse crushing in proportion, medical fluid is contained after pulling the dregs of a decoction out It is good, then adding 4 times of water to decoct a hour filtering medical fluid twice is concentrated into specific gravity together the filtered dregs of a decoction is 1.20- 1.30, A is made.
(2) ash is taken after calcining alum, is crushed, is sieved with 100 mesh sieve, B is made.
(3) selected myrrh, olibanum are crushed into powder at a temperature of 25 DEG C, sieve with 100 mesh sieve, C is made.
(4) B, C are mixed into stir evenly in A and paste is made.
Embodiment 3
Weigh bulk pharmaceutical chemicals: Cortex Phellodendri 40 parts of kg, kiss-me 20kg, alum 25kg, myrrh 15kg, olibanum 6kg.
Weigh bulk pharmaceutical chemicals: Cortex Phellodendri 30 parts of kg, kiss-me 25kg, alum 20kg, myrrh 20kg, olibanum 3kg.
(1) add 4 times of water to decoct a hours after selected Cortex Phellodendri, kiss-me coarse crushing in proportion, medical fluid is contained after pulling the dregs of a decoction out It is good, then adding 8 times of water to decoct a hour filtering medical fluid twice is concentrated into specific gravity together the filtered dregs of a decoction is 1.25- 1.30, A is made.
(2) ash is taken after calcining alum, is crushed, and crosses 80 meshes, B is made.
(3) selected myrrh, olibanum progress are crushed into powder at a temperature of 22 DEG C, cross 120 meshes, C is made.
(4) B, C are mixed into stir evenly in A and paste is made.
Drug of the invention is fine to curative effect in the treatment observation of the patients of cervical ruin of 20 (- 47 years old 25 years old), controls More rate is high, specific as follows: I degree is 9 rotten to the corn in 20 patients, and II degree is 7 rotten to the corn, and III degree is 4 rotten to the corn, has HPV sick Malicious 5 people of patient.Concrete operations: applying after applying ointment on patient's uterine neck, blocked with vaginal plugging, to prevent medical fluid outflow, an at time Between be 12-24 hour, continue second of medicine-feeding after uterine neck wash with distilled water after taking out filling.I degree is added medicine to twice.II degree Medicine-feeding four times is added medicine to three times after the lower menstrual period again after III degree is added medicine to four times.Since other medicines cure rate is extremely low, Therefore do not set control group.As a result are as follows: cure 20 people, cure rate 99%, turn out cloudy in 5 HPV patients 3 people, and effective percentage is 60%.Note Bright: curing is that rotten to the corn face disappearance uterine neck shows that finish is good.

Claims (3)

1. the drug of a kind of anti-treating cervicitis, cervical erosion, it is characterised in that the weight proportion of various bulk pharmaceutical chemicals are as follows: Cortex Phellodendri 30 - 40 parts, 15-25 parts of kiss-me, 15-25 parts of alum, 15-20 parts of myrrh, 3-8 parts of olibanum of part.
2. a kind of preparation method of the drug of anti-treating cervicitis, cervical erosion, it is characterised in that prepare as follows:
(1) add 4-8 times of water to decoct a hour after selected Cortex Phellodendri, kiss-me coarse crushing in proportion, medical fluid contained after pulling the dregs of a decoction out, 4-8 times of water is added to decoct a hour filtering the filtered dregs of a decoction again, it is 1.15- that medical fluid twice is concentrated into specific gravity together 1.30, A is made;
(2) take ash that B is made after taking the alum calcining of proportion deal;
(3) myrrh, the olibanum of selected proportion deal crush at a temperature of 20-25 DEG C, and C is made;
(4) B, C are mixed into A, stir evenly and paste is made.
3. according to claim 2 anti-treating cervicitis, cervical erosion drug preparation method, it is characterised in that: alum is forged Ashing, myrrh, olibanum crushed 80-120 mesh.
CN201810926586.2A 2018-08-15 2018-08-15 A kind of anti-treating cervicitis, drug of cervical erosion and preparation method thereof Pending CN109106784A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101143174A (en) * 2006-09-11 2008-03-19 刘永斌 Traditional Chinese medicine formula for treating cervical erosion

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101143174A (en) * 2006-09-11 2008-03-19 刘永斌 Traditional Chinese medicine formula for treating cervical erosion

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杜廷海等: "《中西医结合妙治疑难病》", 31 August 1998, 河南医科大学出版社 *

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