CN109106741A - Natural anti-cancer drugs and preparation method thereof - Google Patents
Natural anti-cancer drugs and preparation method thereof Download PDFInfo
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- CN109106741A CN109106741A CN201811104641.6A CN201811104641A CN109106741A CN 109106741 A CN109106741 A CN 109106741A CN 201811104641 A CN201811104641 A CN 201811104641A CN 109106741 A CN109106741 A CN 109106741A
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- Prior art keywords
- rock
- cancer drugs
- natural
- natural anti
- plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
- A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
The invention discloses a kind of natural anti-cancer drugs and preparation method thereof, belong to anti-cancer technology field.Natural rock is dissolved using organic acid and plant extracts, is made containing mineral extract and plant extracts in finished product, extraction step is simple and can use directly as anticancer drug.
Description
Technical field
The present invention relates to a kind of natural anti-cancer drugs and preparation method thereof, belong to anti-cancer technology field.
Background technique
Currently, there are many anticancer drugs on the market, and it also proposed the processing of anticancer drug, extracting method.
For example, the rock dusting comprising mineral elements such as aluminium, iron, potassium, then the rock dissolution of dusting is subjected to minerals electricity
Ionization obtains mineral ion liquid, then mineral ion liquid is cooperated coconut oil, oleum maydis, octyl phenol system nonionic circle
Face activating agent etc. is used as detergent.
In addition, also disclose it is a kind of for that will contain the aqueous sodium persulfate solution of electrolysis, and by the inorganic matter containing minerals
The sterilization water solution of the minerals dissolved matter of minerals conversion.
In addition, being saturated with long-pending rock in the unboiled water of room temperature and becoming rock, microorganism is stirred, by 70 ~ 90% ethyl alcohol
It is added with organic acid, makes its fermenting-ripening 2 ~ 3 weeks, and obtained acid generation substance is carried out with alkali stone to neutralization in 7 days.This
The mixture obtained after the mixing such as obstruction-removing prescription, the mixture are heated to 70 ~ 80 DEG C, 30 ~ 40 DEG C, concentrate 10 hour left sides
The powder of the right side, the concentrate starch and micronutrient and the method for addition manufacture healthy food have also been disclosed.
In addition, to aqueous sulfuric acid, aqueous hydrochloric acid solution, aqueous solution of nitric acid, sodium hydroxide, potassium hydroxide, calcium hydroxide
The particulate of mineral of the solution addition containing granite (biotite) is allowed to dissolve mineral and ionization, obtain after removal impurity
The method for taking mineral extract has also been disclosed.
However, producing the anticancer drug containing mineral composition according to the above method, need with nothings such as sulfuric acid, hydrochloric acid, nitric acid
Machine acid carries out dissolution extraction to rock, and a large amount of inorganic acid is introduced in producing process, the mineral extract finally obtained
Also use cannot directly being added doped with inorganic acid, when without extracting using acidolysis, then interminable preparation is needed to extract
Journey, at high cost, low efficiency.
Summary of the invention
Technical problem to be solved by the present invention lies in: a kind of right minerals extracting method is provided, it solves existing
Anticancer drug preparation extraction process is complicated and introducing inorganic acid causes what extract can not use directly as medicine material to ask
Topic.
The technical problems to be solved by the invention take following technical scheme to realize:
Natural anti-cancer drugs, including；
The natural rock of crushing；
Aqueous solutions of organic acids；
The plant extracts being extracted from plants；
Natural anti-cancer drugs are obtained through vacuum drying treatment after three is mixed.
As preferred embodiment, the plant extracts is extracted from seaweed or kelp.
As preferred embodiment, the natural rock is igneous rock.
As preferred embodiment, the natural rock is granite.
As preferred embodiment, the organic acid is acetic acid or citric acid.
As preferred embodiment, the plant extracts is extracted from radish.
As preferred embodiment, in 20 DEG C of -80 DEG C of progress vacuum drying treatments.
As preferred embodiment, the vacuum drying treatment time is 2-24h.
In addition, additionally providing the production method of natural anti-cancer drugs, comprising the following steps:
Natural rock is crushed；
Smashed rock and the aqueous solution containing organic acid are mixed to form mixed liquor；It adds into mixed liquor and extracts from plant
The plant extracts taken；
Vacuum drying treatment is carried out to the mixed liquor for being added to plant extracts and obtains mineral extract.
The production method of natural anti-cancer drugs, it is characterised in that: the plant additive is extracted from seaweed or kelp.
The beneficial effects of the present invention are: rock dissolution is obtained minerals by organic acid, formed after vacuum drying treatment
Grain dress object, is capable of forming colored transparent solution, extraction step is simple, and not introducing inorganic acid product can be direct again when being dissolved in water
It uses.
Detailed description of the invention
Fig. 1 is to take lesion portion comparison diagram before and after natural anti-cancer drugs of the present invention.
Specific embodiment
In order to be easy to understand to technical means, creative features, achievable purpose and effectiveness of the invention, below with reference to tool
Body embodiment, the present invention is further explained.
Natural anti-cancer drugs, the natural rock including crushing；
Aqueous solutions of organic acids；
The plant extracts being extracted from plants；
Natural anti-cancer drugs are obtained through vacuum drying treatment after three is mixed.
Its detailed production method are as follows:
Natural rock is crushed, the partial size of rock is not particularly limited between 1.5-2mm, is crushed using existing means；
Smashed rock and the aqueous solution containing organic acid are mixed to form mixed liquor；
The plant extracts extracted from plant is added into mixed liquor, then filtering after mixed liquor is stood one end time can not
The solid particulate filters of dissolution, time of repose 2-48h, and being advisable with 3-36h, and with 4-24h be it is best, in organic acid and plant
Under the collective effect of object extract, the minerals in rock are dissolved；
Vacuum drying treatment is carried out to the mixed liquor for being added to plant extracts and obtains natural anti-cancer drugs.
Also, moisture removal is removed by then passing through vacuum drying treatment, if it is possible to again be dissolved in obtained shot-like particle
In water, so that it may no longer generation sediment, but the solution of available colored transparent can will mention according to actual needs
Object is taken to save as solid or solution form.
In a kind of embodiment wherein, the plant extracts is extracted from seaweed or kelp, and existing research has shown that,
The ingredient contained in seaweed has the effect for the treatment of cancer, it is pulverized and mixed with rock after extraction and takes resolidification/do not solidify
Production drug and beverage have good therapeutic effect to cancer.
Rock mentioned in the present invention refers to the object being formed by curing by magmatic cooling or deposit continuous action
Matter or the rotten form formed of original rock, are the main matters for constituting the earth's crust and earth mantle.
In a kind of embodiment wherein, the natural rock is igneous rock, and igneous rock includes volcanic rock and plutonic rock, fire
Mountain rock contains rhyolite, andesite and basalt, and plutonic rock contains granite, diabase and spot garland rock.
Further, the natural rock is granite, and granite is high as a kind of general building stones circulation, and compares appearance
Easy to handle, granite can be divided into biotite granite, two mica granites and euchlorite granite, and whatsoever type is ok
It uses.
The main composition object of granite includes quartz, potassium feldspar, plagioclase, biotite, muscovite, hornblende, magnetic
The accessory ingredients mineral such as iron ore, three-bristle cudrania stone, zircon, apatite.
In this application, the main component of granite and its content are limited, be considered as its can by organic acid with
And plant extracts dissolution, and it is capable of forming the solution of colored transparent state.
In addition, the partial size of rock is advisable for 0.5-1.5mm, 1 partial size is that 1mm is most preferably, if it is using ultrasonic grind
Rock is handled, then there is no limit to particle size.
Rock in the application can use the natural rock directly peddled on the market, or after crushing and processing
Rock.
In addition, with used rock as an example, it is preferable to use the crushed material of the rock of about 10 kg on the market, and
The usage amount is not particularly limited, can the device according to used in vacuum drying treatment process type and performance suitably
It is adjusted.By changing the additive amount of rock, the content of the adjustable mineral composition melted from rock can be manufactured
The extract of specified wt out.
In a kind of embodiment wherein, it is most with powdered anhydrous citric acid that the organic acid, which is acetic acid or citric acid,
Good selection, it is also possible to which acetic acid replaces.
In this application, other can also be used and does not do the organic acid limited, if its can as the raw material of diet product,
And it is harmless, then it can select according to the actual situation, the usage amount of organic acid is identical as rock usage amount, about 10kg, but
Be this weight without limitation, adaptability adjusting can be carried out completely in a practical situation.
In a kind of embodiment wherein, the plant extracts is extracted from radish, more specifically, rhizome portion can be used
And/or leaf portion extracts.
In addition, water used in the present invention can be the water for drinking, for example, can fetch water from tap water, still
It is not particularly limited.The usage amount of water is as the case where rock and organic acid, about 10l (about 10 kilograms), but uses
Amount can be adjusted suitably.
In a kind of embodiment wherein, in 20 DEG C of -80 DEG C of progress vacuum drying treatments, it is advisable with 30-60 DEG C, with 35-
45 DEG C are best.
Further, the vacuum drying treatment time is 2-24h, and is advisable with 3-20h, take 4-18h as best, vacuum drying
Processing unit, as long as can just be not necessarily to particularly be restricted directly by liquid handling at the device of vacuum drying treatment, and
Vacuum drying treatment device on the market can suitably be obtained.The vacuum drying treatment equipment is preferably 0k -98kpa, more excellent
Choosing is 96-98 kpa, more preferably 97- 98kpa.The vacuum of 0 kpa may be implemented.In addition, vacuum drying treatment device
Handling the time is preferably 2 ~ 24 hours, and preferably 3 ~ 20 hours, and preferably 4 ~ 18 hours.Therefore, at 24 hours
In the interior short time, the colored transparent solution including rock, organic acid and plant extracts can be solidified.So far, at 100 DEG C
Cryogenic temperature region below, the solution of the colored transparent including rock, organic acid and plant extracts make solidified natural
Object component content constituent is available.
Cured natural anti-cancer drugs are obtained in this way, again plus if water-solubleization, can obtain the coloured of no precipitating
Bright solution.
The natural anti-cancer drugs of the application as adjuvant treatment early-stage cancer, in-one month several days for auxiliary treatment phase
Limit, was advisable with 4-21 day, and be in 5-14 day it is best, take content as 2-50g, be advisable with 4-25g, and with 5-15g for most
Good, daily number is unrestricted.
Applicable object and cancer, such as, lung cancer, gastric cancer, liver cancer, rush adrenal, cancer of pancreas, brain tumor, colorectal cancer, rectum
The cancer of other cancers such as cancer cancer, bile duct cancer, lumbar vertebrae may be applicable in, and not limited especially, can be used as adjuvant treatment
With.
The following are specific embodiments of the present invention, the more detailed explaination present invention, but technical solution of the present invention is not
It is limited by following implementation form.
Embodiment one
The granite that 10kg is purchased from the market is put into pulverizer (Tokyo unicom company of Co., Ltd. produces t -626)
Middle crushing becomes powdered, then the rock of crushing is put into and is previously added 10kg citric acid (concentration after being dissolved in water is 30%)
Aqueous solution in blender in, then into blender add 10kg comminution white radishes, stood after being sufficiently stirred for 24 hours, filtering
Obtain colored transparent solution, then by this solution with vacuum drying treatment device (Co., Ltd. fec corporation fed -500)
In vacuum degree 98kpa, 45 degrees Celsius of temperature processing for 24 hours, obtain powdered mine natural anti-cancer drugs.
If eating above-mentioned natural anti-cancer drugs daily, daily 5g, later observations discovery, hence it is evident that improve body immunity with
And eyesight.
Embodiment two
The granite that 10kg is purchased from the market is put into pulverizer (Tokyo unicom company of Co., Ltd. produces t -626)
Middle crushing becomes powdered, then the rock of crushing is put into and is previously added 10kg citric acid (concentration after being dissolved in water is 30%)
Aqueous solution in blender in, then add into blender the comminution radish (including leaf portion point) and 10kg kelp of 10kg, fill
It is stood for 24 hours after point stirring, is obtained by filtration colored transparent solution, then by this solution vacuum drying treatment device (Co., Ltd. f
Ec corporation fed -500) in vacuum degree 98kpa, 45 degrees Celsius of temperature processing for 24 hours, obtain powdered natural anti-cancer drugs.
The natural anti-cancer drugs prepared in embodiment two are taken, wherein also added kelp, it is auxiliary to can be used as treatment of cancer
Help use.
Fig. 1 (a) and Fig. 1 (c) is the mri image of a patient, is brain tumor, liver cancer, mri image.It is attached in national university
Belong to the attending physician of hospital patient is carried out to allow patient to take the natural anticancer medical in the present invention after the service life only has two weeks pronounce
Object, daily 5g, result such as such as the Fig. 1 (b) and Fig. 1 (d), lesion locations persistently taken 2 weeks are obviously improved, finally and are obtained
To recovery from illness, it was demonstrated that play key effect during auxiliary for treating cancer, anticancer.
To sum up, product of the present invention dissolves rock using organic acid and plant extracts, obtains natural mineral matter extract,
Preparation process is simple, wherein containing natural mineral matter extract and plant extracts, has anticancer effect.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, without departing from the spirit and scope of the present invention, this hair
Bright to will also have various changes and improvements, these changes and improvements are both fallen in the scope of protection of present invention.The present invention claims
Protection scope is defined by the appending claims and its equivalent thereof.
Claims (10)
1. natural anti-cancer drugs, it is characterised in that: including；
The natural rock of crushing；
Aqueous solutions of organic acids；
The plant extracts being extracted from plants；
Natural anti-cancer drugs are obtained through vacuum drying treatment after three is mixed.
2. natural anti-cancer drugs according to claim 1, it is characterised in that: the plant extracts is from seaweed or kelp
It extracts.
3. natural anti-cancer drugs according to claim 1, it is characterised in that: the natural rock is igneous rock.
4. natural anti-cancer drugs according to claim 3, it is characterised in that: the natural rock is granite.
5. natural anti-cancer drugs according to claim 1, it is characterised in that: the organic acid is acetic acid or citric acid.
6. natural anti-cancer drugs according to claim 1, it is characterised in that: the plant extracts is extracted from radish.
7. natural anti-cancer drugs according to claim 1-6, it is characterised in that: in 20 DEG C of -80 DEG C of progress vacuum
It is dried.
8. natural anti-cancer drugs according to claim 7, it is characterised in that: the vacuum drying treatment time is 2-24h.
9. the production method of natural anti-cancer drugs, it is characterised in that: the following steps are included:
Natural rock is crushed；
Smashed rock and the aqueous solution containing organic acid are mixed to form mixed liquor；It adds into mixed liquor and extracts from plant
The plant extracts taken；
Vacuum drying treatment is carried out to the mixed liquor for being added to plant extracts and obtains mineral extract.
10. the production method of natural anti-cancer drugs, it is characterised in that: the plant additive is extracted from seaweed or kelp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811104641.6A CN109106741A (en) | 2018-09-21 | 2018-09-21 | Natural anti-cancer drugs and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811104641.6A CN109106741A (en) | 2018-09-21 | 2018-09-21 | Natural anti-cancer drugs and preparation method thereof |
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| Publication Number | Publication Date |
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| CN109106741A true CN109106741A (en) | 2019-01-01 |
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| CN201811104641.6A Pending CN109106741A (en) | 2018-09-21 | 2018-09-21 | Natural anti-cancer drugs and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017128488A (en) * | 2016-01-19 | 2017-07-27 | 敏明 齋藤 | Production method of composition containing component derived from natural product, composition containing component derived from natural product, and functional food and drink using the same |
| CN108310287A (en) * | 2018-04-26 | 2018-07-24 | 深圳安济堂医药科技有限公司 | Oral solution for the treatment of cancer and preparation method thereof |
-
2018
- 2018-09-21 CN CN201811104641.6A patent/CN109106741A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017128488A (en) * | 2016-01-19 | 2017-07-27 | 敏明 齋藤 | Production method of composition containing component derived from natural product, composition containing component derived from natural product, and functional food and drink using the same |
| CN108310287A (en) * | 2018-04-26 | 2018-07-24 | 深圳安济堂医药科技有限公司 | Oral solution for the treatment of cancer and preparation method thereof |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190101 |
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