CN109106468A - A kind of artificial blood vessel structure that can improve compliance - Google Patents
A kind of artificial blood vessel structure that can improve compliance Download PDFInfo
- Publication number
- CN109106468A CN109106468A CN201810920397.4A CN201810920397A CN109106468A CN 109106468 A CN109106468 A CN 109106468A CN 201810920397 A CN201810920397 A CN 201810920397A CN 109106468 A CN109106468 A CN 109106468A
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- Prior art keywords
- yarn
- blood vessel
- textured
- elastomeric
- polyester
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- 210000004204 blood vessel Anatomy 0.000 title claims abstract description 68
- 239000002473 artificial blood Substances 0.000 title claims abstract description 28
- 229920000728 polyester Polymers 0.000 claims abstract description 21
- 239000000203 mixture Substances 0.000 claims abstract description 7
- 238000010276 construction Methods 0.000 claims abstract description 5
- 239000004744 fabric Substances 0.000 claims description 16
- 239000010410 layer Substances 0.000 claims description 12
- 238000009954 braiding Methods 0.000 claims description 7
- 230000008859 change Effects 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 238000009941 weaving Methods 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 5
- 230000008602 contraction Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 230000009471 action Effects 0.000 claims description 3
- 238000009940 knitting Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 239000002344 surface layer Substances 0.000 claims description 3
- 238000005253 cladding Methods 0.000 claims description 2
- 238000000465 moulding Methods 0.000 claims description 2
- 230000002792 vascular Effects 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 2
- 238000005516 engineering process Methods 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000004753 textile Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 238000013459 approach Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 description 1
- 230000002008 hemorrhagic effect Effects 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 238000012805 post-processing Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Prostheses (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
Abstract
The present invention relates to a kind of artificial blood vessel structures that can improve compliance, belong to medical instruments field, using machine-knitted structure, which is characterized in that it is polyester's blood vessel, and the ectonexine of polyester's blood vessel weaves satin construction, and warp thread uses PET textured yarn;The middle layer of polyester's blood vessel weaves plain weave, and warp thread uses PET long filament;In the ectonexine of polyester's blood vessel, middle layer, weft yarn is using textured yarn or the complex yarn of elastomeric yarn, inelastic yarn composition.Compared with the existing technology, the invention has the benefit that artificial blood vessel of the invention, since weft yarn uses the complex yarn using textured yarn or elastomeric yarn, inelastic yarn composition, the radial diameter of blood vessel can be made to adapt to the demand of human body, vascular compliance improves 3% ~ 5%.
Description
Technical field
The present invention relates to a kind of artificial blood vessel structures that can improve compliance, belong to medical instruments field.
Background technique
Earliest artificial blood vessel invention is in the U.S., about in 40 ~ fifties of 20th century.Developed since nineteen fifty-seven artificial in China
Blood vessel, and the transfer operation of big or middle artery has been carried out on the basis of a large amount of zooperies, achieve relatively satisfactory effect.Closely
Over a little years, textile artificial blood vessel has been largely used to clinic, but there are still some problems.The antiseepage for how optimizing artificial blood vessel is hemorrhagic
Energy, biocompatibility, is easy to cell and the performances such as grows into become focus concerned by people in recent years compliance.
Clinically, vascular compliance is defined as the variation of pressure-dependent vessel area, diameter or volume.Blood vessel is suitable
Answering property is exactly adaptability of the blood vessel to the blood of flowing, in favor of the proper flow of blood in the blood vessel.Artificial blood vessel is for replacing
It for autologous vein, needs under the diastole systolic pressure of certain frequency, the ability with radial elastic expansion and contraction.Difference knot
The artificial blood vessel of structure, compliance are also variant.For example, the artificial blood vessel of knitting and the preparation of polyurethane high molecule material, compliance
Respectively 1.97% and 2.9%, woven blood vessel, ePTFE artificial blood vessel compliance are poor, < 1%.Human vas is radially complied with
Property for 5%/1000 mmHg or so.There are also documents and materials to show, superior using different raw materials, such as using PPT long filament
Elastic property, weave artificial blood vessel as weft yarn, the compliance of blood vessel can be improved." one kind can improve radial direction to Chinese patent
The textile artificial blood vessel of compliance " (failure), publication number CN201803964A designed by the structure of woven blood vessel,
The ectonexine of blood vessel is formed, to improve blood vessel radial compliance, but compliance is still only between 0.4 ~ 2.8%, and only refers to list
The compliance of layer (internal layer or outer layer), is not introduced whole vascular compliance.
People in all its bearings, such as material selection, fabric construction, post-processing approach, are explored and are improved, but so far,
The compliance of artificial blood vessel still cannot be comparable with human body artery.
Summary of the invention
To solve drawbacks described above existing in the prior art, the present invention provides a kind of artificial blood vessel knot that can improve compliance
Structure, the difference to solve after artificial blood vessel is implanted to human body in the prior art, under the conditions of fluctuation pressure, with autologous vein compliance
It is different.
To achieve the goals above, a kind of the technical solution adopted by the present invention are as follows: artificial blood vessel knot that can improve compliance
Structure, using machine-knitted structure, which is characterized in that it is polyester's blood vessel, and the ectonexine of polyester's blood vessel weaves satin construction,
Warp thread uses PET textured yarn;The middle layer of polyester's blood vessel weaves plain weave, and warp thread uses PET long filament;Polyester's blood
In the ectonexine of pipe, middle layer, weft yarn is using textured yarn or the complex yarn of elastomeric yarn, inelastic yarn composition.
Weft yarn is obtained by way of braiding or doubling, and simultaneously containing textured yarn or elastomeric yarn and non-elastic yarn
Line;Wherein, elastomeric yarn or textured yarn are coated or are coated by inelastic yarn half, and inelastic yarn is presented on polyester's blood
The surface layer (i.e. ectonexine) of pipe, elastomeric yarn or textured yarn are presented on the internal layer (middle layer) of fabric.
The weft yarn, is obtained by the way of doubling, when doubling, to textured yarn or elastomeric yarn, inelastic yarn
And yarn tension is controlled, the tension setting value of the warp tension ratio inelastic yarn of textured yarn or elastomeric yarn is small, so that in nature
Under state, in a length, the length of yarn of inelastic yarn is longer than the length of elastomeric yarn or textured yarn, to meet it one
Under fixed tension, identical elongation can be reached.Weft yarn after intercepting certain length doubling, by textured yarn or elastomeric yarn, non-ballistic
Property yarn separation, apply certain pre-tension, so that two kinds of yarns are in straight configuration, at this point, the yarn of inelastic yarn
Line length is longer than the length of elastomeric yarn or textured yarn by 5% ~ 8%.
The weft yarn, is obtained by the way of braiding, when braiding, using elastomeric yarn or textured yarn as heart yarn, PET
Long filament forms covering yarn as wrap yarn on braider;Wrap yarn is adjusted as required by the state modulator of braider
Angle and density are worked out, to meet when yarn is integrally straightened, elastomeric yarn or textured yarn are stretched 5% ~ 8%.Intercept a fixed length
Heart yarn and wrap yarn are separated, apply certain pre-tension by the weft yarn of degree, so that two kinds of yarns are in straight configuration, this
When, elastomeric yarn is stretched 5% ~ 8%.
The weft yarn, inelastic yarn are made of one or more yarns, and textured yarn or elastomeric yarn are by one
Or threads composition.
The weft yarn, in weaving process, textured yarn or elastomeric yarn are straightened under the action of weft tension;Fabric is knitted
After causing type, elastomeric yarn or textured yarn have certain contraction, so that fabric (i.e. polyester's blood vessel) diameter reduces, certain
Under pressure, fabric radially has 3% ~ 5% diameter change;After pressure disappears, fabric is restored to original size again.
Polyester's blood vessel adds coating after finishing the weaving, then in polyester's blood vessel outer surface.
Compared with the existing technology, the invention has the benefit that artificial blood vessel of the invention, uses since weft yarn uses
The complex yarn of textured yarn or elastomeric yarn, inelastic yarn composition, can make the radial diameter of blood vessel adapt to the need of human body
It asks, vascular compliance improves 3% ~ 5% or so.
Detailed description of the invention
Fig. 1, Fig. 2, Fig. 3 are structural schematic diagrams of the invention.
Specific embodiment
To keep the technological means realized, creation characteristic, the purpose reached and effect of the invention more clear and being apparent to,
With reference to the accompanying drawing and specific embodiment the present invention is further elaborated.
A kind of polyester's blood vessel, using machine-knitted structure, ectonexine weaves satin construction, and warp thread uses PET textured yarn, in
Interbed weaves plain weave, and warp thread uses PET long filament.Weft yarn is answered using what textured yarn or elastomeric yarn, inelastic yarn formed
Yarns, i.e. weft yarn must contain inelastic yarn, the also at least one containing textured yarn or elastomeric yarn.Textured yarn is elasticity
One kind of yarn.
Polyester's blood vessel, weft yarn braiding or doubling by way of obtain, and constituent there are two types of or two
Kind or more (simultaneously containing textured yarn or elastomeric yarn and inelastic yarn).Wherein, elastomeric yarn or textured yarn are non-resilient
Yarn half coats or cladding, and inelastic yarn is presented on the surface layer of fabric, and elastomeric yarn or textured yarn are presented on the interior of fabric
Layer.
The weft yarn can be obtained by the way of doubling, then when needing to pass through doubling, to textured yarn or elastomeric yarn
Line, inelastic yarn and yarn tension controlled, the setting of the tension of the warp tension ratio inelastic yarn of textured yarn or elastomeric yarn
Value wants small, so that in its natural state, in a length, the length of yarn of inelastic yarn is longer than elastomeric yarn or textured yarn
Degree length, to meet it under certain tension, can reach identical elongation.Weft yarn after intercepting certain length doubling, will deform
Yarn or elastomeric yarn, inelastic yarn separation, apply certain pre-tension, so that two kinds of yarns are in straight configuration, this
When, the length of yarn of inelastic yarn is longer than the length of elastomeric yarn or textured yarn by 5% ~ 8%.
The weft yarn can be obtained by the way of braiding, be needed elastomeric yarn or textured yarn, such as PU long filament,
As heart yarn, PET long filament (it is inelastic yarn) is used as wrap yarn, and covering yarn is formed on braider.Wrap yarn can lead to
Establishment angle and density is adjusted as required in the state modulator for crossing braider, to meet the elastomeric yarn when yarn is integrally straightened
Line or textured yarn are stretched.Heart yarn and wrap yarn are separated, apply certain pre-tension, make by the weft yarn for intercepting certain length
Two kinds of yarns are in straight configuration, at this point, elastomeric yarn is stretched 5% ~ 8%.
The weft yarn, non-elastic yarn are made of one or more yarns, textured yarn or elastomeric yarn by one or
Person's threads composition.
The weft yarn, in weaving process, textured yarn or elastomeric yarn are straightened under the action of weft tension;Fabric knitting
After molding, textured yarn or elastomeric yarn have certain contraction, so that fabric diameter reduces;By the test device of compliance, one
Under fixed pressure, radial direction has 3% ~ 5% or so diameter change;After pressure disappears, fabric is restored to original size again.
The artificial blood vessel adds coating after finishing the weaving.
Embodiment 1
Such as Fig. 1, the invention discloses a kind of blood vessel structures that can improve compliance, use the complex tissue of plain weave and satin weave.
Its weft yarn, by twisting after doubling, forms complex yarn using the FDY of the DTY and 80D of 80D.When DTY, FDY doubling, using not
Same tension control system and super-feeding device, so that the overfeed ratio of FDY is the 5% of DTY.When twisting, DTY tension value is set as
The tension value 2CN, DTY of 1CN, FDY are transferred to yarn outer layer.Blood vessel after coating, by the test device of compliance,
The blood vessel applies under the dynamic pressure of 26.7kpa, and the diameter change of blood vessel is the 3.7% of natural diameter.
Embodiment 2
Such as Fig. 2, the invention discloses a kind of blood vessel structures that can improve compliance, use the complex tissue of plain weave and satin weave.
Its weft yarn uses covering yarn, and heart yarn uses 80D PU yarn, and wrap yarn uses 80D PET yarn, and the braid angle of PET yarn is arranged
It is 100 °, PET forms helicoidal structure in outer ring.Blood vessel after coating is applied by the test device of compliance in the blood vessel
Under the dynamic pressure for adding 26.7kpa, the diameter change of blood vessel is the 4.0% of natural diameter.
Embodiment 3
Such as Fig. 3, the invention discloses a kind of blood vessel structures that can improve compliance, use the complex tissue of plain weave and satin weave.
Its weft yarn uses covering yarn, and heart yarn uses 40D*2 PET textured yarn, and wrap yarn uses 40D*2 PET long filament, the volume of PET long filament
It knits angle and is set as 100 °, wrap yarn forms helicoidal structure in outer ring.Blood vessel after coating is filled by the test of compliance
It sets, under the dynamic pressure that the blood vessel applies 26.7kpa, the diameter change of blood vessel is the 4.2% of natural diameter.
The above is only a preferred embodiment of the present invention, it should be pointed out that: for the ordinary skill people of the art
For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (7)
1. a kind of artificial blood vessel structure that can improve compliance, using machine-knitted structure, which is characterized in that it is polyester's blood
Pipe, the ectonexine of polyester's blood vessel weave satin construction, and warp thread uses PET textured yarn;The middle layer of polyester's blood vessel is knitted
Plain weave is made, warp thread uses PET long filament;In the ectonexine of polyester's blood vessel, middle layer, weft yarn uses textured yarn or elasticity
The complex yarn of yarn, inelastic yarn composition.
2. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that weft yarn passes through volume
It knits or the mode of doubling obtains, and simultaneously containing textured yarn or elastomeric yarn and inelastic yarn;Wherein, elastomeric yarn or change
Shape yarn is coated or cladding by inelastic yarn half, and inelastic yarn is presented on the surface layer of polyester's blood vessel, elastomeric yarn or
Textured yarn is presented on the internal layer of fabric.
3. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude
Yarn is obtained by the way of doubling, when doubling, to textured yarn or elastomeric yarn, inelastic yarn and yarn tension control,
The tension setting value of the warp tension ratio inelastic yarn of textured yarn or elastomeric yarn is small, so that in its natural state, in a length,
The length of yarn of inelastic yarn is 5% ~ 8% more than the length of elastomeric yarn or textured yarn.
4. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude
Yarn is obtained by the way of braiding, when braiding, using elastomeric yarn or textured yarn as heart yarn, PET long filament as wrap yarn,
Covering yarn is formed on braider;Establishment angle and density is adjusted as required by the state modulator of braider in wrap yarn, with full
For foot when yarn is integrally straightened, elastomeric yarn or textured yarn are stretched 5% ~ 8%.
5. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude
Yarn, inelastic yarn are made of one or more yarns, and textured yarn or elastomeric yarn are made of one or more yarns.
6. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude
Yarn, in weaving process, textured yarn or elastomeric yarn are straightened under the action of weft tension;After fabric knitting molding, elastomeric yarn
Line or textured yarn have certain contraction so that fabric diameter reduce, under pressure, fabric radially have 3% ~ 5% it is straight
Diameter variation;After pressure disappears, fabric is restored to original size again.
7. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the polyester
Artificial blood vessel adds coating after finishing the weaving, then in polyester's blood vessel outer surface.
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CN201810920397.4A CN109106468B (en) | 2018-08-14 | 2018-08-14 | Artificial blood vessel structure capable of improving compliance |
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CN201810920397.4A CN109106468B (en) | 2018-08-14 | 2018-08-14 | Artificial blood vessel structure capable of improving compliance |
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CN109106468B CN109106468B (en) | 2023-12-01 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110604633A (en) * | 2019-10-18 | 2019-12-24 | 江苏百优达生命科技有限公司 | Vascular stent covering film with integrated variable structure and manufacturing method thereof |
CN110859998A (en) * | 2019-12-18 | 2020-03-06 | 上海畅迪医疗科技有限公司 | Anti-kink artificial blood vessel and preparation method thereof |
CN116990161A (en) * | 2023-09-26 | 2023-11-03 | 江苏恒力化纤股份有限公司 | External fatigue simulation device for chemical fiber filaments and fatigue resistance comparison method |
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CN1060023A (en) * | 1990-09-18 | 1992-04-08 | 苏州医学院 | Machine made synthetic small blood vessel |
US20040221623A1 (en) * | 2000-02-16 | 2004-11-11 | Viktoria Kantsevitcha | Vascular prosthesis |
CN101084846A (en) * | 2007-03-21 | 2007-12-12 | 林增华 | Double-layer weaving polyester artificial vascular |
CN102206888A (en) * | 2011-05-30 | 2011-10-05 | 东华大学 | Integrally formed three-layer woven simulation artificial blood vessel |
CN102212918A (en) * | 2011-05-30 | 2011-10-12 | 东华大学 | Three-layer weaved small-caliber artificial blood vessel and preparation method thereof |
CN102920531A (en) * | 2012-11-08 | 2013-02-13 | 东华大学 | Production method of woven artificial blood vessel |
CN209422164U (en) * | 2018-08-14 | 2019-09-24 | 江苏百优达生命科技有限公司 | A kind of artificial blood vessel structure that can improve compliance |
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Patent Citations (7)
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CN1060023A (en) * | 1990-09-18 | 1992-04-08 | 苏州医学院 | Machine made synthetic small blood vessel |
US20040221623A1 (en) * | 2000-02-16 | 2004-11-11 | Viktoria Kantsevitcha | Vascular prosthesis |
CN101084846A (en) * | 2007-03-21 | 2007-12-12 | 林增华 | Double-layer weaving polyester artificial vascular |
CN102206888A (en) * | 2011-05-30 | 2011-10-05 | 东华大学 | Integrally formed three-layer woven simulation artificial blood vessel |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110604633A (en) * | 2019-10-18 | 2019-12-24 | 江苏百优达生命科技有限公司 | Vascular stent covering film with integrated variable structure and manufacturing method thereof |
CN110604633B (en) * | 2019-10-18 | 2024-03-05 | 江苏百优达生命科技有限公司 | Vascular stent coating film with integrally variable structure and manufacturing method thereof |
CN110859998A (en) * | 2019-12-18 | 2020-03-06 | 上海畅迪医疗科技有限公司 | Anti-kink artificial blood vessel and preparation method thereof |
CN116990161A (en) * | 2023-09-26 | 2023-11-03 | 江苏恒力化纤股份有限公司 | External fatigue simulation device for chemical fiber filaments and fatigue resistance comparison method |
CN116990161B (en) * | 2023-09-26 | 2024-02-06 | 江苏恒力化纤股份有限公司 | External fatigue simulation device for chemical fiber filaments and fatigue resistance comparison method |
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