CN109106468A - A kind of artificial blood vessel structure that can improve compliance - Google Patents

A kind of artificial blood vessel structure that can improve compliance Download PDF

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Publication number
CN109106468A
CN109106468A CN201810920397.4A CN201810920397A CN109106468A CN 109106468 A CN109106468 A CN 109106468A CN 201810920397 A CN201810920397 A CN 201810920397A CN 109106468 A CN109106468 A CN 109106468A
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China
Prior art keywords
yarn
blood vessel
textured
elastomeric
polyester
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CN201810920397.4A
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Chinese (zh)
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CN109106468B (en
Inventor
奚敏敏
杜广武
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Jiangsu 100 Uni-Data Life Science & Technology Co Ltd
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Jiangsu 100 Uni-Data Life Science & Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels

Abstract

The present invention relates to a kind of artificial blood vessel structures that can improve compliance, belong to medical instruments field, using machine-knitted structure, which is characterized in that it is polyester's blood vessel, and the ectonexine of polyester's blood vessel weaves satin construction, and warp thread uses PET textured yarn;The middle layer of polyester's blood vessel weaves plain weave, and warp thread uses PET long filament;In the ectonexine of polyester's blood vessel, middle layer, weft yarn is using textured yarn or the complex yarn of elastomeric yarn, inelastic yarn composition.Compared with the existing technology, the invention has the benefit that artificial blood vessel of the invention, since weft yarn uses the complex yarn using textured yarn or elastomeric yarn, inelastic yarn composition, the radial diameter of blood vessel can be made to adapt to the demand of human body, vascular compliance improves 3% ~ 5%.

Description

A kind of artificial blood vessel structure that can improve compliance
Technical field
The present invention relates to a kind of artificial blood vessel structures that can improve compliance, belong to medical instruments field.
Background technique
Earliest artificial blood vessel invention is in the U.S., about in 40 ~ fifties of 20th century.Developed since nineteen fifty-seven artificial in China Blood vessel, and the transfer operation of big or middle artery has been carried out on the basis of a large amount of zooperies, achieve relatively satisfactory effect.Closely Over a little years, textile artificial blood vessel has been largely used to clinic, but there are still some problems.The antiseepage for how optimizing artificial blood vessel is hemorrhagic Energy, biocompatibility, is easy to cell and the performances such as grows into become focus concerned by people in recent years compliance.
Clinically, vascular compliance is defined as the variation of pressure-dependent vessel area, diameter or volume.Blood vessel is suitable Answering property is exactly adaptability of the blood vessel to the blood of flowing, in favor of the proper flow of blood in the blood vessel.Artificial blood vessel is for replacing It for autologous vein, needs under the diastole systolic pressure of certain frequency, the ability with radial elastic expansion and contraction.Difference knot The artificial blood vessel of structure, compliance are also variant.For example, the artificial blood vessel of knitting and the preparation of polyurethane high molecule material, compliance Respectively 1.97% and 2.9%, woven blood vessel, ePTFE artificial blood vessel compliance are poor, < 1%.Human vas is radially complied with Property for 5%/1000 mmHg or so.There are also documents and materials to show, superior using different raw materials, such as using PPT long filament Elastic property, weave artificial blood vessel as weft yarn, the compliance of blood vessel can be improved." one kind can improve radial direction to Chinese patent The textile artificial blood vessel of compliance " (failure), publication number CN201803964A designed by the structure of woven blood vessel, The ectonexine of blood vessel is formed, to improve blood vessel radial compliance, but compliance is still only between 0.4 ~ 2.8%, and only refers to list The compliance of layer (internal layer or outer layer), is not introduced whole vascular compliance.
People in all its bearings, such as material selection, fabric construction, post-processing approach, are explored and are improved, but so far, The compliance of artificial blood vessel still cannot be comparable with human body artery.
Summary of the invention
To solve drawbacks described above existing in the prior art, the present invention provides a kind of artificial blood vessel knot that can improve compliance Structure, the difference to solve after artificial blood vessel is implanted to human body in the prior art, under the conditions of fluctuation pressure, with autologous vein compliance It is different.
To achieve the goals above, a kind of the technical solution adopted by the present invention are as follows: artificial blood vessel knot that can improve compliance Structure, using machine-knitted structure, which is characterized in that it is polyester's blood vessel, and the ectonexine of polyester's blood vessel weaves satin construction, Warp thread uses PET textured yarn;The middle layer of polyester's blood vessel weaves plain weave, and warp thread uses PET long filament;Polyester's blood In the ectonexine of pipe, middle layer, weft yarn is using textured yarn or the complex yarn of elastomeric yarn, inelastic yarn composition.
Weft yarn is obtained by way of braiding or doubling, and simultaneously containing textured yarn or elastomeric yarn and non-elastic yarn Line;Wherein, elastomeric yarn or textured yarn are coated or are coated by inelastic yarn half, and inelastic yarn is presented on polyester's blood The surface layer (i.e. ectonexine) of pipe, elastomeric yarn or textured yarn are presented on the internal layer (middle layer) of fabric.
The weft yarn, is obtained by the way of doubling, when doubling, to textured yarn or elastomeric yarn, inelastic yarn And yarn tension is controlled, the tension setting value of the warp tension ratio inelastic yarn of textured yarn or elastomeric yarn is small, so that in nature Under state, in a length, the length of yarn of inelastic yarn is longer than the length of elastomeric yarn or textured yarn, to meet it one Under fixed tension, identical elongation can be reached.Weft yarn after intercepting certain length doubling, by textured yarn or elastomeric yarn, non-ballistic Property yarn separation, apply certain pre-tension, so that two kinds of yarns are in straight configuration, at this point, the yarn of inelastic yarn Line length is longer than the length of elastomeric yarn or textured yarn by 5% ~ 8%.
The weft yarn, is obtained by the way of braiding, when braiding, using elastomeric yarn or textured yarn as heart yarn, PET Long filament forms covering yarn as wrap yarn on braider;Wrap yarn is adjusted as required by the state modulator of braider Angle and density are worked out, to meet when yarn is integrally straightened, elastomeric yarn or textured yarn are stretched 5% ~ 8%.Intercept a fixed length Heart yarn and wrap yarn are separated, apply certain pre-tension by the weft yarn of degree, so that two kinds of yarns are in straight configuration, this When, elastomeric yarn is stretched 5% ~ 8%.
The weft yarn, inelastic yarn are made of one or more yarns, and textured yarn or elastomeric yarn are by one Or threads composition.
The weft yarn, in weaving process, textured yarn or elastomeric yarn are straightened under the action of weft tension;Fabric is knitted After causing type, elastomeric yarn or textured yarn have certain contraction, so that fabric (i.e. polyester's blood vessel) diameter reduces, certain Under pressure, fabric radially has 3% ~ 5% diameter change;After pressure disappears, fabric is restored to original size again.
Polyester's blood vessel adds coating after finishing the weaving, then in polyester's blood vessel outer surface.
Compared with the existing technology, the invention has the benefit that artificial blood vessel of the invention, uses since weft yarn uses The complex yarn of textured yarn or elastomeric yarn, inelastic yarn composition, can make the radial diameter of blood vessel adapt to the need of human body It asks, vascular compliance improves 3% ~ 5% or so.
Detailed description of the invention
Fig. 1, Fig. 2, Fig. 3 are structural schematic diagrams of the invention.
Specific embodiment
To keep the technological means realized, creation characteristic, the purpose reached and effect of the invention more clear and being apparent to, With reference to the accompanying drawing and specific embodiment the present invention is further elaborated.
A kind of polyester's blood vessel, using machine-knitted structure, ectonexine weaves satin construction, and warp thread uses PET textured yarn, in Interbed weaves plain weave, and warp thread uses PET long filament.Weft yarn is answered using what textured yarn or elastomeric yarn, inelastic yarn formed Yarns, i.e. weft yarn must contain inelastic yarn, the also at least one containing textured yarn or elastomeric yarn.Textured yarn is elasticity One kind of yarn.
Polyester's blood vessel, weft yarn braiding or doubling by way of obtain, and constituent there are two types of or two Kind or more (simultaneously containing textured yarn or elastomeric yarn and inelastic yarn).Wherein, elastomeric yarn or textured yarn are non-resilient Yarn half coats or cladding, and inelastic yarn is presented on the surface layer of fabric, and elastomeric yarn or textured yarn are presented on the interior of fabric Layer.
The weft yarn can be obtained by the way of doubling, then when needing to pass through doubling, to textured yarn or elastomeric yarn Line, inelastic yarn and yarn tension controlled, the setting of the tension of the warp tension ratio inelastic yarn of textured yarn or elastomeric yarn Value wants small, so that in its natural state, in a length, the length of yarn of inelastic yarn is longer than elastomeric yarn or textured yarn Degree length, to meet it under certain tension, can reach identical elongation.Weft yarn after intercepting certain length doubling, will deform Yarn or elastomeric yarn, inelastic yarn separation, apply certain pre-tension, so that two kinds of yarns are in straight configuration, this When, the length of yarn of inelastic yarn is longer than the length of elastomeric yarn or textured yarn by 5% ~ 8%.
The weft yarn can be obtained by the way of braiding, be needed elastomeric yarn or textured yarn, such as PU long filament, As heart yarn, PET long filament (it is inelastic yarn) is used as wrap yarn, and covering yarn is formed on braider.Wrap yarn can lead to Establishment angle and density is adjusted as required in the state modulator for crossing braider, to meet the elastomeric yarn when yarn is integrally straightened Line or textured yarn are stretched.Heart yarn and wrap yarn are separated, apply certain pre-tension, make by the weft yarn for intercepting certain length Two kinds of yarns are in straight configuration, at this point, elastomeric yarn is stretched 5% ~ 8%.
The weft yarn, non-elastic yarn are made of one or more yarns, textured yarn or elastomeric yarn by one or Person's threads composition.
The weft yarn, in weaving process, textured yarn or elastomeric yarn are straightened under the action of weft tension;Fabric knitting After molding, textured yarn or elastomeric yarn have certain contraction, so that fabric diameter reduces;By the test device of compliance, one Under fixed pressure, radial direction has 3% ~ 5% or so diameter change;After pressure disappears, fabric is restored to original size again.
The artificial blood vessel adds coating after finishing the weaving.
Embodiment 1
Such as Fig. 1, the invention discloses a kind of blood vessel structures that can improve compliance, use the complex tissue of plain weave and satin weave. Its weft yarn, by twisting after doubling, forms complex yarn using the FDY of the DTY and 80D of 80D.When DTY, FDY doubling, using not Same tension control system and super-feeding device, so that the overfeed ratio of FDY is the 5% of DTY.When twisting, DTY tension value is set as The tension value 2CN, DTY of 1CN, FDY are transferred to yarn outer layer.Blood vessel after coating, by the test device of compliance, The blood vessel applies under the dynamic pressure of 26.7kpa, and the diameter change of blood vessel is the 3.7% of natural diameter.
Embodiment 2
Such as Fig. 2, the invention discloses a kind of blood vessel structures that can improve compliance, use the complex tissue of plain weave and satin weave. Its weft yarn uses covering yarn, and heart yarn uses 80D PU yarn, and wrap yarn uses 80D PET yarn, and the braid angle of PET yarn is arranged It is 100 °, PET forms helicoidal structure in outer ring.Blood vessel after coating is applied by the test device of compliance in the blood vessel Under the dynamic pressure for adding 26.7kpa, the diameter change of blood vessel is the 4.0% of natural diameter.
Embodiment 3
Such as Fig. 3, the invention discloses a kind of blood vessel structures that can improve compliance, use the complex tissue of plain weave and satin weave. Its weft yarn uses covering yarn, and heart yarn uses 40D*2 PET textured yarn, and wrap yarn uses 40D*2 PET long filament, the volume of PET long filament It knits angle and is set as 100 °, wrap yarn forms helicoidal structure in outer ring.Blood vessel after coating is filled by the test of compliance It sets, under the dynamic pressure that the blood vessel applies 26.7kpa, the diameter change of blood vessel is the 4.2% of natural diameter.
The above is only a preferred embodiment of the present invention, it should be pointed out that: for the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (7)

1. a kind of artificial blood vessel structure that can improve compliance, using machine-knitted structure, which is characterized in that it is polyester's blood Pipe, the ectonexine of polyester's blood vessel weave satin construction, and warp thread uses PET textured yarn;The middle layer of polyester's blood vessel is knitted Plain weave is made, warp thread uses PET long filament;In the ectonexine of polyester's blood vessel, middle layer, weft yarn uses textured yarn or elasticity The complex yarn of yarn, inelastic yarn composition.
2. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that weft yarn passes through volume It knits or the mode of doubling obtains, and simultaneously containing textured yarn or elastomeric yarn and inelastic yarn;Wherein, elastomeric yarn or change Shape yarn is coated or cladding by inelastic yarn half, and inelastic yarn is presented on the surface layer of polyester's blood vessel, elastomeric yarn or Textured yarn is presented on the internal layer of fabric.
3. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude Yarn is obtained by the way of doubling, when doubling, to textured yarn or elastomeric yarn, inelastic yarn and yarn tension control, The tension setting value of the warp tension ratio inelastic yarn of textured yarn or elastomeric yarn is small, so that in its natural state, in a length, The length of yarn of inelastic yarn is 5% ~ 8% more than the length of elastomeric yarn or textured yarn.
4. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude Yarn is obtained by the way of braiding, when braiding, using elastomeric yarn or textured yarn as heart yarn, PET long filament as wrap yarn, Covering yarn is formed on braider;Establishment angle and density is adjusted as required by the state modulator of braider in wrap yarn, with full For foot when yarn is integrally straightened, elastomeric yarn or textured yarn are stretched 5% ~ 8%.
5. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude Yarn, inelastic yarn are made of one or more yarns, and textured yarn or elastomeric yarn are made of one or more yarns.
6. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the latitude Yarn, in weaving process, textured yarn or elastomeric yarn are straightened under the action of weft tension;After fabric knitting molding, elastomeric yarn Line or textured yarn have certain contraction so that fabric diameter reduce, under pressure, fabric radially have 3% ~ 5% it is straight Diameter variation;After pressure disappears, fabric is restored to original size again.
7. a kind of artificial blood vessel structure that can improve compliance according to claim 1, which is characterized in that the polyester Artificial blood vessel adds coating after finishing the weaving, then in polyester's blood vessel outer surface.
CN201810920397.4A 2018-08-14 2018-08-14 Artificial blood vessel structure capable of improving compliance Active CN109106468B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110604633A (en) * 2019-10-18 2019-12-24 江苏百优达生命科技有限公司 Vascular stent covering film with integrated variable structure and manufacturing method thereof
CN110859998A (en) * 2019-12-18 2020-03-06 上海畅迪医疗科技有限公司 Anti-kink artificial blood vessel and preparation method thereof
CN116990161A (en) * 2023-09-26 2023-11-03 江苏恒力化纤股份有限公司 External fatigue simulation device for chemical fiber filaments and fatigue resistance comparison method

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CN1060023A (en) * 1990-09-18 1992-04-08 苏州医学院 Machine made synthetic small blood vessel
US20040221623A1 (en) * 2000-02-16 2004-11-11 Viktoria Kantsevitcha Vascular prosthesis
CN101084846A (en) * 2007-03-21 2007-12-12 林增华 Double-layer weaving polyester artificial vascular
CN102206888A (en) * 2011-05-30 2011-10-05 东华大学 Integrally formed three-layer woven simulation artificial blood vessel
CN102212918A (en) * 2011-05-30 2011-10-12 东华大学 Three-layer weaved small-caliber artificial blood vessel and preparation method thereof
CN102920531A (en) * 2012-11-08 2013-02-13 东华大学 Production method of woven artificial blood vessel
CN209422164U (en) * 2018-08-14 2019-09-24 江苏百优达生命科技有限公司 A kind of artificial blood vessel structure that can improve compliance

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1060023A (en) * 1990-09-18 1992-04-08 苏州医学院 Machine made synthetic small blood vessel
US20040221623A1 (en) * 2000-02-16 2004-11-11 Viktoria Kantsevitcha Vascular prosthesis
CN101084846A (en) * 2007-03-21 2007-12-12 林增华 Double-layer weaving polyester artificial vascular
CN102206888A (en) * 2011-05-30 2011-10-05 东华大学 Integrally formed three-layer woven simulation artificial blood vessel
CN102212918A (en) * 2011-05-30 2011-10-12 东华大学 Three-layer weaved small-caliber artificial blood vessel and preparation method thereof
CN102920531A (en) * 2012-11-08 2013-02-13 东华大学 Production method of woven artificial blood vessel
CN209422164U (en) * 2018-08-14 2019-09-24 江苏百优达生命科技有限公司 A kind of artificial blood vessel structure that can improve compliance

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110604633A (en) * 2019-10-18 2019-12-24 江苏百优达生命科技有限公司 Vascular stent covering film with integrated variable structure and manufacturing method thereof
CN110604633B (en) * 2019-10-18 2024-03-05 江苏百优达生命科技有限公司 Vascular stent coating film with integrally variable structure and manufacturing method thereof
CN110859998A (en) * 2019-12-18 2020-03-06 上海畅迪医疗科技有限公司 Anti-kink artificial blood vessel and preparation method thereof
CN116990161A (en) * 2023-09-26 2023-11-03 江苏恒力化纤股份有限公司 External fatigue simulation device for chemical fiber filaments and fatigue resistance comparison method
CN116990161B (en) * 2023-09-26 2024-02-06 江苏恒力化纤股份有限公司 External fatigue simulation device for chemical fiber filaments and fatigue resistance comparison method

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