CN109091133A - Blood pressure and the signal processing of intracranial pressure and clinical parameter algorithm - Google Patents
Blood pressure and the signal processing of intracranial pressure and clinical parameter algorithm Download PDFInfo
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- CN109091133A CN109091133A CN201811161868.4A CN201811161868A CN109091133A CN 109091133 A CN109091133 A CN 109091133A CN 201811161868 A CN201811161868 A CN 201811161868A CN 109091133 A CN109091133 A CN 109091133A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
- A61B5/031—Intracranial pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
Abstract
The invention discloses blood pressures and the signal processing of intracranial pressure and clinical parameter algorithm, are related to medicine and hygiene fields, algorithm of the invention obtains mean pressure by complete integral mean operation;Based on sine wave it is assumed that integrating the positive differential pressure in duration to one section seeks 2 times of square roots, multiplied byAlong with mean pressure, in this, as systolic pressure;Based on sine wave it is assumed that integrating the negative sense differential pressure in duration to one section seeks 2 times of square roots, multiplied byThe calculated result for subtracting front with mean pressure again, in this, as systolic pressure;It can accomplish the intracorporal blood pressure of accurate, quick and stable measurement and intracranial pressure using algorithm disclosed in this invention, and effectively inhibit breathing wave interference.
Description
" technical field "
The present invention relates to medicine and hygiene fields, calculate more particularly to blood pressure and the signal processing of intracranial pressure and clinical parameter
Method.
" background technique "
Due to heartbeat, blood pressure and intracranial pressure are characterized in being superimposed with arteries and veins on certain static pressure basis
Dynamic pressure.Blood pressure becomes apparent from than the ripple amplitude of intracranial pressure.
Blood pressure and the monitoring mode of intracranial pressure are divided into noninvasive and two kinds invasive.Invasive mode due to it is more accurate and reliable by
Clinic is regarded as being goldstandard.Invasive blood mode is also known as the direct method of measurement, is directly passed by establishing pressure with measuring point
Channel is passed, obtains instantaneous pressure using pressure sensor.
Instantaneous pressure must pass through processing and calculating, can just obtain each clinical parameter of blood pressure and intracranial pressure.Blood pressure
Clinical parameter is mainly systolic pressure and diastolic pressure, further includes mean pressure;And the clinical parameter of intracranial pressure is mainly mean pressure, is also wrapped
Include systolic pressure and diastolic pressure.Systolic pressure refers to wave crest pressure, and diastolic pressure refers to trough pressure, and mean pressure refers to average pressure.
According to such definition, waveform morphology method of identification is usually used when signal processing and clinical parameter calculate, first
Property period of waves is recognized, the position of each wave crest and trough is found, then obtains wave crest pressure, trough by series of computation
Pressure and average pressure.Actual blood pressure and intracranial pressure waveform are complicated and changeable, and are random.Therefore, accurate
Ground captures and distinguishes each period, each wave crest and each trough and is difficult, even not possible with.Misjudgement or leakage
Very big error will be brought to final result by falling a wave crest or a trough, and numerical value will be jumped significantly, is unstable.
Also someone improves waveform morphology using the extremely complex mathematical algorithm such as multiple averaging, auto-correlation, wavelet transformation
Method of identification.This will occupy that a large amount of computing resource efficiency is very low, and bring larger delay, the reaction of final measurement
Slowly.Most importantly, they can not also prevent the case where misjudging or miss wave crest or trough generation completely, and effect is not to manage very much
Think, accuracy of measurement can only be assessed based on probability.These have its day based on probability rather than based on the algorithm of physics principle
Right theoretical defects, it is necessary to compared by a large amount of clinical database to verify the validity of its measurement result.
" summary of the invention "
Based on the shortcomings of the prior art, the purpose of the present invention is to provide at a kind of blood pressure and monitoring intracranial pressure signal
Adjustment method, which utilizes instantaneous pressure obtained, by handling and being calculated wave crest pressure, trough pressure and mean pressure
Power, respectively as systolic pressure, diastolic pressure and mean pressure.Algorithm energy is accurate, quick and stablizes, moreover it is possible to effectively inhibit respiratory wave dry
It disturbs.
The scope of application of the invention also includes relevant to heartbeat other than blood pressure and the signal processing of intracranial pressure
The signal processing of other internal pressure.
To achieve the above object, the following technical solution is employed by the present invention:
The calculating of mean pressure
Using instantaneous pressure, suitable calculating parameter is selected according to application demand and technical standard, by completely integrating
Average value operation, obtains mean pressure, and algorithm is shown in formula (1).
In formula,
MEAm--- mean pressure;
Pi--- instantaneous pressure;
The data sequence number of m--- mean pressure;
The data sequence number of i--- instantaneous pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- instantaneous pressure refers to interior data amount check obtained per second, unit: sps, samples
Per second, sample number per second;
k1--- calibration factor is the constant set to eliminate the gain error of mean pressure.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to take after removal decimal
Integer.
Preferably, the data rate F value 20sps of instantaneous pressure.
Preferably, the data rate of mean pressure is f, and the value of f is 1sps.
Preferably, duration T value 6s is integrated.
Preferably, calibration factor k1Value is close to 1.
The calculating of systolic pressure and diastolic pressure
S1: the calculating of mean pressure
The calculated result of mean pressure is both one independent as a result, also walking as one of systolic pressure and the calculating of diastole
Suddenly.
S2: the calculating of positive differential pressure and negative sense differential pressure
Positive differential pressure and negative sense differential pressure are the intermediate variables being defined, they will be used to calculate systolic pressure and diastolic pressure.
Using instantaneous pressure, suitable calculating parameter is selected according to application demand and technical standard, then carry out subsequent meter
It calculates.The instantaneous pressure in duration first is integrated to one section to average, and then again makees each instantaneous pressure with corresponding average value
Multilevel iudge.Retain the difference portion that instantaneous pressure is greater than average value if instantaneous pressure is greater than average value, if instantaneous pressure
Power is less than average value and then retains 0, in this, as positive differential pressure.Retain average value if instantaneous pressure is less than average value greater than wink
When pressure difference portion, if instantaneous pressure be greater than average value if retain 0, in this, as negative sense differential pressure.Algorithm is shown in formula (2)
(3).
In above two formula,
DPn--- positive differential pressure;
DNn--- negative sense differential pressure;
Pi--- instantaneous pressure;
The data sequence number of n--- forward direction differential pressure and negative sense differential pressure;
The data sequence number of i--- instantaneous pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- instantaneous pressure refers to interior data amount check obtained per second, unit: sps, samples
Per second, sample number per second.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to take after removal decimal
Integer.
Preferably, the data rate F value 20sps of instantaneous pressure.
Preferably, positive differential pressure, the data rate F phase that the data rate of negative sense differential pressure is identical and with instantaneous pressure are same
Sample, value 20sps.
Preferably, duration T value 6s is integrated.
S3: the calculating of systolic pressure and diastolic pressure
Resulting positive differential pressure, negative sense differential pressure are calculated using from instantaneous pressure, is selected according to application demand and technical standard
Suitable calculating parameter, then carry out subsequent calculating.Based on sine wave it is assumed that integrating the positive differential pressure in duration to one section asks 2
Square root again, multiplied byAlong with mean pressure, in this, as systolic pressure.Based on sine wave it is assumed that when to one section of integral
Negative sense differential pressure in length seeks 2 times of square roots, multiplied byThe calculated result for subtracting front with mean pressure again, in this, as receipts
Contracting pressure.Algorithm is shown in formula (4) and (5).
In above two formula,
SYSm--- systolic pressure;
DIAm--- diastolic pressure;
MEAm--- mean pressure;
DPn--- positive differential pressure;
DNn--- negative sense differential pressure;
M--- systolic pressure, diastolic pressure, mean pressure data sequence number;
The data sequence number of n--- forward direction differential pressure, negative sense differential pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- forward direction differential pressure, negative sense differential pressure refers to the data amount check in per second, unit: sps,
Samples per second, sample number per second;
k2--- calibration factor is the constant set to eliminate the gain error of systolic pressure;
k3--- calibration factor is the constant set to eliminate the gain error of diastolic pressure.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to take after removal decimal
Integer.
Preferably, the data rate F value 20sps of instantaneous pressure.
Preferably, systolic pressure, the data rate f that the data rate of diastolic pressure is identical and with mean pressure are identical, value 1sps.
Preferably, duration T value 6s is integrated.
Preferably, calibration factor k2And k3Value is close to 1.
The invention has the advantages that mean pressure, systolic pressure and diastolic pressure steadily accurate, quickly can be calculated, also
It can effectively inhibit to breathe wave interference.
" Detailed description of the invention "
Fig. 1 is the diagram that blood pressure provided by the invention or intracranial pressure waveform and its clinical parameter define.
Fig. 2 is algorithm schematic diagram of the invention.
Fig. 3-1~Fig. 3-8 is respectively provided by the embodiment of the present invention one: data rate is the instantaneous pressure P wave of 20sps
The mean pressure MEA wave that shape, the instantaneous pressure P waveform that the data rate for being superimposed with respiration interference is 20sps, output speed are 1sps
Square waveform for the positive differential pressure DP that waveform of averaging, the data rate that shape, data rate are 20sps are 20sps, data speed
Square waveform, the data rate 1sps for the negative sense differential pressure DN that systolic pressure SYS waveform that rate is 1sps, data rate are 20sps
Diastolic pressure DIA waveform;Fig. 3-1~Fig. 3-8 abscissa is data sequence number.
Fig. 4-1~Fig. 4-8 is respectively provided by the embodiment of the present invention two: data rate is the instantaneous pressure P wave of 40sps
The mean pressure MEA wave that shape, the instantaneous pressure P waveform that the data rate for being superimposed with respiration interference is 40sps, output speed are 1sps
Square waveform for the positive differential pressure DP that waveform of averaging, the data rate that shape, data rate are 40sps are 40sps, data speed
Square waveform, the data rate 1sps for the negative sense differential pressure DN that systolic pressure SYS waveform that rate is 1sps, data rate are 40sps
Diastolic pressure DIA waveform;Fig. 4-1~Fig. 4-8 abscissa is data sequence number.
" specific embodiment "
In order to which technical solution of the present invention is more clearly understood, the present invention is made below in conjunction with attached drawing and specific embodiment
It further illustrates.
As shown in Figure 1, systolic pressure refers to wave crest pressure, diastolic pressure refers to trough pressure, and mean pressure refers to average pressure.
As shown in Fig. 2, illustrating the overall situation of algorithm, facilitate have comprehensive, overall understanding to algorithm by it.
The calculating of mean pressure
The algorithm of mean pressure is shown in formula (1).
In formula,
MEAm--- mean pressure;
Pi--- instantaneous pressure;
The data sequence number of m--- mean pressure;
The data sequence number of i--- instantaneous pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- instantaneous pressure refers to interior data amount check obtained per second, unit: sps, samples
Per second, sample number per second;
k1--- calibration factor is the constant set to eliminate the gain error of mean pressure.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to take after removal decimal
Integer.
To embodiment one, F=20sps;To embodiment two, F=40sps.The the data rate F of instantaneous pressure the big, calculates
As a result more accurate and calculated load is heavier, should compromise selects value, general 10~1000sps of value.
The data rate of mean pressure is f, refers to the calculated data amount check of interior institute per second and formula (1) is per second interior is counted
The number of calculation, unit: sps, samples per second, sample number per second.F=1sps.The data rate f of mean pressure is bigger
Then Refresh Data speed more block and calculated load is heavier, should compromise selects value, general 0.2~5sps of value.
T=6s.Integrate duration T more it is big then result is more accurate and phase delay is bigger, should compromise and select value.According to YY
4.2.6 in 1079-2008, heart rate measurement range are 30~250bpm (bpm, beats perminute, heartbeat per minute time
Number).For HR min 30bpm here, 3 cardiac cycle of duration T value is integrated, is exactly 6s, general value 5~
10s。
k1=1.Calibration factor k1Value, general value 0.8~1.2 are determined according to test result.
The calculating of systolic pressure and diastolic pressure
S1: the calculating of mean pressure
The calculated result of mean pressure is both one independent as a result, also walking as one of systolic pressure and the calculating of diastole
Suddenly.
S2: the calculating of positive differential pressure and negative sense differential pressure
Positive differential pressure and negative sense differential pressure are the intermediate variables being defined, they will be used to calculate systolic pressure and diastolic pressure.
The algorithm of positive differential pressure and negative sense differential pressure is shown in formula (2) and (3).
In above two formula,
DPn--- positive differential pressure;
DNn--- negative sense differential pressure;
Pi--- instantaneous pressure;
The data sequence number of n--- forward direction differential pressure and negative sense differential pressure;
The data sequence number of i--- instantaneous pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- instantaneous pressure refers to interior data amount check obtained per second, unit: sps, samples
Per second, sample number per second.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to take after removal decimal
Integer.
The data rate of instantaneous pressure, to embodiment one, F=20sps;To embodiment two, F=40sps.Instantaneous pressure
Data rate F more it is big then calculated result is more accurate and calculated load is heavier, should compromise selects value, general value 10~
1000sps。
In order to improve computational efficiency, the data of positive differential pressure, negative sense differential pressure using whole instantaneous pressure datas to greatest extent
Rate refers to the calculated data amount check of interior institute per second and formula (2) and (3) interior number calculated per second, both of which one
Sample, and as the data rate of instantaneous pressure, so do not make difference all is indicated with F herein.To embodiment one, F=
20sps;To embodiment two, F=40sps.
T=6s.Integrate duration T more it is big then result is more accurate and phase delay is bigger, should compromise and select value.According to YY
4.2.6 in 1079-2008, heart rate measurement range are 30~250bpm (bpm, beats per minute, heartbeat per minute time
Number).For HR min 30bpm here, 3 cardiac cycle of duration T value is integrated, is exactly 6s, general value 5~
10s。
S3: the calculating of systolic pressure and diastolic pressure
According to 51.102.2 and Figure 114 in YY 0783-2010/IEC 60601-2-34:2000, the test used is believed
Number be the sine wave of bi-directional symmetrical, thought be think to handle instantaneous pressure as the sine wave of bi-directional symmetrical and and without
Carry out apparent error or basic just without error.Therefore the present invention is based on sine wave it is assumed that using sine wave root-mean-square value
(virtual value) and peak value have this principle of particular kind of relationship, with root-mean-square value (virtual value) multiplied byEqual to peak value, received as calculating
Contracting pressure and the basis for systolic pressure.
Systolic pressure and formula (4) and (5) are seen for the algorithm of systolic pressure.
In above two formula,
SYSm--- systolic pressure;
DIAm--- diastolic pressure;
MEAm--- mean pressure;
DPn--- positive differential pressure;
DNn--- negative sense differential pressure;
M--- systolic pressure, diastolic pressure, mean pressure data sequence number;
The data sequence number of n--- forward direction differential pressure, negative sense differential pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- forward direction differential pressure, negative sense differential pressure refers to the data amount check in per second, unit: sps, samples
Per second, sample number per second;
k2--- calibration factor is the constant set to eliminate the gain error of systolic pressure;
k3--- calibration factor is the constant set to eliminate the gain error of diastolic pressure.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to take after removal decimal
Integer.
The data rate of positive differential pressure, negative sense differential pressure, both of which is the same, and with the data rate of instantaneous pressure one
Sample, so do not make difference all is indicated with F herein.To embodiment one, F=20sps;To embodiment two, F=40sps.It is positive poor
Pressure, negative sense differential pressure data rate F more it is big then calculated result is more accurate and calculated load is heavier, should compromise selects value, generally
10~1000sps of value.
The data rate of systolic pressure, diastolic pressure refers to that interior calculated data amount check and formula (4) per second and (5) are per second
Interior number calculated, unit: sps, samples per second, sample number per second.Both of which is the same, and with it is average
The data rate of pressure is the same, so do not make difference all is indicated with f herein.F=1sps.The data rate f of systolic pressure, diastolic pressure
More big then Refresh Data speed more block and calculated load is heavier, should compromise selects value, general 0.2~5sps of value.
T=6s.Integrate duration T more it is big then result is more accurate and phase delay is bigger, should compromise and select value.According to YY
4.2.6 in 1079-2008, heart rate measurement range are 30~250bpm (bpm, beats perminute, heartbeat per minute time
Number).For HR min 30bpm here, 3 cardiac cycle of duration T value is integrated, is exactly 6s, general value 5~
10s。
k2=1, k3=1.Calibration factor k2And k3Value, general value 0.8~1.2 are determined according to test result.They
Between be independent, onrelevant.
It as shown in Figure 3 and Figure 4, is the simulation results of embodiment one and embodiment two respectively.Ordinate is respective
The variable of title, abscissa are data sequence numbers.
According to the sine wave of instantaneous pressure it is assumed that being superimposed the instantaneous pressure P of respiration interferenceiMathematic(al) representation are as follows:
In formula,
Pi--- it has been superimposed the instantaneous pressure of respiration interference;
The data sequence number of i--- instantaneous pressure.
Used parameter is as follows:
To embodiment one, the data rate F=20sps of instantaneous pressure, positive differential pressure, negative sense differential pressure;To embodiment two, wink
When pressure, positive differential pressure, negative sense differential pressure data rate F=40sps.
The data rate f=1sps of mean pressure, systolic pressure and diastolic pressure
Integrate duration T=6s
Heart rate HR=90bpm
Systolic pressure SYS=120mmHg
Diastolic pressure DIA=80mmHg
Respiratory rate RR=15bpm
Amplitude A=6mmHg of respiration interference
Simulation result meets expection, and the present invention accurate, quickly steadily can calculate mean pressure, systolic pressure and diastole
Pressure, breathing wave interference, which is also effectively suppressed, to become smaller.
The content that the present invention is not limited to hereinbefore be specifically illustrated in and described.However the scope of the present invention is by appended power
Sharp claim limits, and the combination including above-mentioned various features and sub-portfolio and those skilled in the art are reading above-mentioned retouch
Its variations and modifications conceived after stating.Many equivalents, alternative, change and modification are all possible and of the invention
Within the scope of.
Claims (2)
1. blood pressure and the signal processing of intracranial pressure and clinical parameter algorithm, it is characterised in that: the algorithm can calculate average
Pressure, algorithm are as follows:
Using instantaneous pressure, suitable calculating parameter is selected according to application demand and technical standard, passes through complete integral mean
It is worth operation, obtains mean pressure, algorithm is shown in formula (1).
In formula,
MEAm--- mean pressure;
Pi--- instantaneous pressure;
The data sequence number of m--- mean pressure;
The data sequence number of i--- instantaneous pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- instantaneous pressure refers to interior data amount check obtained per second, unit: sps, samples per
Second, sample number per second;
k1--- calibration factor is the constant set to eliminate the gain error of mean pressure.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to carry out round numbers after removal decimal.
2. blood pressure as described in claim 1 and the signal processing of intracranial pressure and clinical parameter algorithm, it is characterised in that: further include
The algorithm of diastolic pressure and systolic pressure, detailed process is as follows with clinical parameter algorithm for the signal processing:
S1: the mean pressure MEAmCalculating;
S2: the calculating of positive differential pressure and negative sense differential pressure
Positive differential pressure and negative sense differential pressure are the intermediate variables being defined, they will be used to calculate systolic pressure and diastolic pressure.
Using instantaneous pressure, suitable calculating parameter is selected according to application demand and technical standard, then carry out subsequent calculating.First
The instantaneous pressure in duration is integrated to one section to average, and each instantaneous pressure is made comparisons again with corresponding average value then and is sentenced
It is disconnected.Retain the difference portion that instantaneous pressure is greater than average value if instantaneous pressure is greater than average value, if instantaneous pressure is less than
Average value then retains 0, in this, as positive differential pressure.Retain average value if instantaneous pressure is less than average value greater than instantaneous pressure
Difference portion, if instantaneous pressure be greater than average value if retain 0, in this, as negative sense differential pressure.Algorithm is shown in formula (2) and (3).
In above two formula,
DPn--- positive differential pressure;
DNn--- negative sense differential pressure;
Pi--- instantaneous pressure;
The data sequence number of n--- forward direction differential pressure and negative sense differential pressure;
The data sequence number of i--- instantaneous pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- instantaneous pressure refers to interior data amount check obtained per second, unit: sps, samples per
Second, sample number per second.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to carry out round numbers after removal decimal.
S3: the calculating of systolic pressure and diastolic pressure
Resulting positive differential pressure, negative sense differential pressure are calculated using from instantaneous pressure, it is suitable to select according to application demand and technical standard
Calculating parameter, then carry out subsequent calculating.Based on sine wave it is assumed that one section integrate duration in positive differential pressure ask 2 times
The root of side, multiplied byAlong with mean pressure, in this, as systolic pressure.Based on sine wave it is assumed that in one section of integral duration
Negative sense differential pressure seek 2 times of square roots, multiplied byThe calculated result for subtracting front with mean pressure again, in this, as contraction
Pressure.Algorithm is shown in formula (4) and (5).
In above two formula,
SYSm--- systolic pressure;
DIAm--- diastolic pressure;
MEAm--- mean pressure;
DPn--- positive differential pressure;
DNn--- negative sense differential pressure;
M--- systolic pressure, diastolic pressure, mean pressure data sequence number;
The data sequence number of n--- forward direction differential pressure, negative sense differential pressure;
T--- integrates duration, refers to the time span of integral mean operation;
The data rate of F--- forward direction differential pressure, negative sense differential pressure refers to the data amount check in per second, unit: sps, samples per
Second, sample number per second;
k2--- calibration factor is the constant set to eliminate the gain error of systolic pressure;
k3--- calibration factor is the constant set to eliminate the gain error of diastolic pressure.
TF then directly removes decimal place if it is non-integer, or rounds up, or integer-bit adds 1 to carry out round numbers after removal decimal.
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CN112494019A (en) * | 2020-11-26 | 2021-03-16 | 苏州润迈德医疗科技有限公司 | Method for extracting flat stable pressure waveform based on aortic pressure and storage medium |
WO2022110019A1 (en) * | 2020-11-26 | 2022-06-02 | 苏州润迈德医疗科技有限公司 | Aortic pressure waveform image generation method and storage medium |
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2018
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Publication number | Priority date | Publication date | Assignee | Title |
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CN112494019A (en) * | 2020-11-26 | 2021-03-16 | 苏州润迈德医疗科技有限公司 | Method for extracting flat stable pressure waveform based on aortic pressure and storage medium |
WO2022110021A1 (en) * | 2020-11-26 | 2022-06-02 | 苏州润迈德医疗科技有限公司 | Method for extracting stable pressure waveform on the basis of aortic pressure, and storage medium |
WO2022110019A1 (en) * | 2020-11-26 | 2022-06-02 | 苏州润迈德医疗科技有限公司 | Aortic pressure waveform image generation method and storage medium |
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