CN109077352A - A kind of addiction and heroinomania product - Google Patents
A kind of addiction and heroinomania product Download PDFInfo
- Publication number
- CN109077352A CN109077352A CN201810734237.0A CN201810734237A CN109077352A CN 109077352 A CN109077352 A CN 109077352A CN 201810734237 A CN201810734237 A CN 201810734237A CN 109077352 A CN109077352 A CN 109077352A
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- Prior art keywords
- addiction
- product
- heroinomania
- cigarette
- raw material
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/14—Use of materials for tobacco smoke filters of organic materials as additive
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Medicinal Preparation (AREA)
Abstract
A kind of addiction and heroinomania product of the present invention, wherein when the raw material preparation of addiction and heroinomania product: being protected from light, the fine powders of 100 mesh or more is made under room temperature the tetrahydropalmatine of active constituent；Acidic water-soluble solvent is added in the fine powder under the conditions of being protected from light, suspension is made, obtain the raw material of the addiction and heroinomania product, the wherein mixture of at least one of the acidic water-soluble aqueous solvent, ether, chloroform and C2-C5 alcohol alcohol, wherein the acid contained is sulfuric acid or hydrochloric acid.When preparing raw material in the present invention, ether and chloroform are increased in a solvent, so that tetrahydropalmatine can be good at dissolving, and then improve the preventive effect of the raw material of addiction and heroinomania product, and the product being prepared can alleviate drugs such as morphine withrawal symptom and inhibit to drugs heart addiction, non-toxic, not habituation, pharmacological dependence is not formed, it is easy to use.
Description
Technical field
The invention belongs to article technical fields of quitting drug abuse, and in particular to a kind of addiction and heroinomania product.
Background technique
Drugs have become one of global social concern of current most serious.It has been reported that the whole world has about 600,000,000 people to be related to inhaling
Poison is shown according to the statistical data of prohibition of drug committee of China publication, by the end of the year in 2014, the accumulative registration drug addict 295.5 ten thousand in China
Name, estimation effective strength is more than 14,000,000, and most of drug addicts can not extricate oneself after catching drug addiction.Life of the drugs to the mankind
It deposits and development constitutes great threat, cause the common concern of countries in the world.
Banning drugs work is very urgent, and while sternly hitting drug-pedlar's poison processed, drug rehabilitation is a weight in banning drugs work
Want link.For a long time, people have carried out a large amount of exploration and research to the prohibition of drug, and therapy of quitting drug abuse at present mainly has Cold turkey treatment
Method, diminishing method, method of substitution etc.；Used therapeutic agent is most of or uses Western medicine, such as opioid drug methadone and its
His non-opium drug, such as clonidine, Verapamil.Though such as such drug of opioid drug methadone can be reduced drug abuse
The withrawal symptom that person occurs during drug rehabilitation adapts to its body gradually, can smoothly release to the physiology of drugs according to
Rely, realizes drug rehabilitation, however these drugs are quit drug abuse by then passing through opiate receptor, new additive or dependence easy to form, i.e.,
It is also easy to produce " with poison generation poison "；Such as other non-opium drugs, such as clonidine, Verapamil, side effect is more, patient medication
Afterwards, many discomforts can be generated in terms of body, to bring different degrees of pain and mental handicape to patient, curative effect also fails
It is very satisfied.
What the patent document of Publication No. CN 1392777A disclosed a kind of addiction and heroinomania contains tetiahydriopalmatimefor for curing opium
Product and preparation method thereof, the tetiahydriopalmatimefor for curing opium of active constituent is being protected from light, the fine powders of 100 mesh or more is made under room temperature；?
Suspension is made to get raw material is arrived in the Plus acidic water-soluble solvent of fine powder under the conditions of being protected from light, the raw material is mixed via dispersion
It is bonded in product, and then obtains the product.Although the product can alleviate drugs such as morphine withrawal symptom and inhibit to drugs
Heart addiction, non-toxic, habituation, does not form pharmacological dependence, easy to use, but solvent in the preparation method of the raw material of this kind of product
For tetiahydriopalmatimefor for curing opium dissolubility also wait improve so that the content of tetiahydriopalmatimefor for curing opium there are certain deviation, influences prevention and guards against
The preventive effect of product is relapsed after poison.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of preparation method of the raw material of addiction and heroinomania product,
Improve the preventive effect of the raw material of addiction and heroinomania product.
The technical solution of the present invention is as follows: a kind of preparation method of the raw material of addiction and heroinomania product, comprising:
(1) tetrahydropalmatine of active constituent is being protected from light, the fine powders of 100 mesh or more is made under room temperature；
(2) acidic water-soluble solvent is added in the fine powder under the conditions of being protected from light and suspension is made to get to described pre-
The raw material of product is relapsed after anti-drug rehabilitation, wherein in the acidic water-soluble aqueous solvent, ether, chloroform and C2-C5 alcohol
The mixture of at least one alcohol, wherein the acid contained is sulfuric acid or hydrochloric acid.
Preferably, the acidity aqueous solvent is at least one of ether and chloroform, wherein the acid contained is sulphur
Acid or hydrochloric acid.
Preferably, the alcohol is ethyl alcohol, propyl alcohol, propylene glycol, butanol, butanediol, amylalcohol, pentanediol or its mixing
Object.
The present invention also provides a kind of raw materials of addiction and heroinomania product that above-mentioned preparation method is prepared.
The present invention also provides a kind of preparation methods of the cigarette of addiction and heroinomania characterized by comprising will be upper
The raw material for the addiction and heroinomania product stated uniformly is sprayed on pipe tobacco and is uniformly mixed the cigarette cut tobacco obtained later by normal
The cigarette preparation method of rule is rolled and is packed；Or, capsule and pill is made in suspension granulation, and it is put into the filter tip of cigarette.
Preferably, content of the tetrahydropalmatine in every cigarette is 1~10 milligram, wherein pipe tobacco contains in cigarette
Amount is 800 milligrams.
Preferably, content of the tetrahydropalmatine in every cigarette is 3~5 milligrams.
The present invention also provides the cigarettes that the preparation method of the cigarette of above-mentioned addiction and heroinomania is prepared.
The present invention also provides a kind of products of addiction and heroinomania, are mixed in the product by above-mentioned stock dispersion
Among be prepared.
Preferably, product is beverage as claimed in claim.
Compared with prior art, the beneficial effects of the present invention are embodied in:
When the present invention prepares raw material, ether and chloroform are increased in a solvent, enable tetrahydropalmatine fine
Dissolution, and then improve the preventive effect of the raw material of addiction and heroinomania product, and the product being prepared can be alleviated
Drugs such as morphine withrawal symptom simultaneously inhibits to drugs heart addiction, and non-toxic, habituation, does not form pharmacological dependence, easy to use,
Specific embodiment
Embodiment 1
(1) tetrahydropalmatine of active constituent is being protected from light, the fine powders of 100 mesh or more is made under room temperature；
(2) acidic water-soluble solvent is added in the fine powder under the conditions of being protected from light and suspension is made to get to described pre-
The raw material of product is relapsed after anti-drug rehabilitation, wherein in the acidic water-soluble aqueous solvent, ether, chloroform and C2-C5 alcohol
Mixture, wherein the acid contained is sulfuric acid or hydrochloric acid；
(3) it is obtained after the raw material of above-mentioned addiction and heroinomania product being uniformly sprayed on pipe tobacco and is uniformly mixed
Cigarette cut tobacco cigarette preparation method routinely roll and pack, wherein content of the tetrahydropalmatine in every cigarette is 1
Milligram.
Embodiment 2
Embodiment 2 is different from that of the embodiment 1 only in the following aspects: tetrahydropalmatine in every cigarette (800 milligrams of pipe tobaccos)
Content be 10 milligrams.
Embodiment 3
Embodiment 3 is different from that of the embodiment 1 only in the following aspects: tetrahydropalmatine in every cigarette (800 milligrams of pipe tobaccos)
Content be 5 milligrams.
Embodiment 4
Embodiment 4 is different from that of the embodiment 1 only in the following aspects: tetrahydropalmatine in every cigarette (800 milligrams of pipe tobaccos)
Content be 8 milligrams.
Embodiment 5
Embodiment 5 the difference is that only with embodiment 4: capsule and pill is made in suspension granulation, and is put into the mistake of cigarette
In filter tip.
Test example
By embodiment 4, the embodiment 5, (perfume (or spice) being prepared in the patent document of Publication No. CN 1392777A of comparative example 1
Cigarette) and the cigarette of comparative example 2 (cigarettes) be supplied to drug addict and suck, drug abstainer at least sucks 3 preventions drug rehabilitations daily
The cigarette relapsed afterwards can be taken effect；The drug abstainer big for daily smoking capacity, the present invention will not generate any adverse reaction.
In clinical trial, embodiment 4, embodiment 5, comparative example 1 and comparative example 2 are respectively using 30 drug abstainers as using after detoxification
Cigarette prolong and checks withrawal symptom and compare.It the results are shown in Table 1.
Table 1
Claims (10)
1. a kind of preparation method of the raw material of addiction and heroinomania product, comprising:
(1) tetrahydropalmatine of active constituent is being protected from light, the fine powders of 100 mesh or more is made under room temperature；
(2) suspension is made in the fine powder addition acidic water-soluble solvent under the conditions of being protected from light to guard against to get to the prevention
The raw material of product is relapsed after poison, wherein in the acidic water-soluble aqueous solvent, ether, chloroform and C2-C5 alcohol at least
A kind of mixture of alcohol, wherein the acid contained is sulfuric acid or hydrochloric acid.
2. the preparation method of the raw material of addiction and heroinomania product as described in claim 1, which is characterized in that the acidity
Aqueous solvent is at least one of ether and chloroform, wherein the acid contained is sulfuric acid or hydrochloric acid.
3. the preparation method of the raw material of addiction and heroinomania product as described in claim 1, which is characterized in that the alcohol
For or mixtures thereof ethyl alcohol, propyl alcohol, propylene glycol, butanol, butanediol, amylalcohol, pentanediol.
4. a kind of raw material for the addiction and heroinomania product that the preparation method as described in claims 1 to 3 is any is prepared.
5. a kind of preparation method of the cigarette of addiction and heroinomania characterized by comprising will be as claimed in claim 4 pre-
The raw material that product is relapsed after anti-drug rehabilitation is uniformly sprayed on pipe tobacco and is uniformly mixed the perfume (or spice) of the cigarette cut tobacco obtained later routinely
Cigarette preparation method is rolled and is packed；Or, capsule and pill is made in suspension granulation, and it is put into the filter tip of cigarette.
6. the preparation method of the cigarette of addiction and heroinomania as claimed in claim 5, which is characterized in that the tetrahydro bar horse
Content of the spit of fland in every cigarette is 1~10 milligram, and wherein tobacco content is 800 milligrams in cigarette.
7. the preparation method of the cigarette of addiction and heroinomania as claimed in claim 6, which is characterized in that the tetrahydro bar horse
Content of the spit of fland in every cigarette is 3~5 milligrams.
8. the cigarette that the preparation method of the cigarette of the addiction and heroinomania as described in claim 5~7 is any is prepared.
9. a kind of product of addiction and heroinomania, which is characterized in that be mixed in by stock dispersion as claimed in claim 4 described
It is prepared among product.
10. the product of addiction and heroinomania as claimed in claim 9, which is characterized in that product is as claimed in claim
Beverage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810734237.0A CN109077352A (en) | 2018-07-06 | 2018-07-06 | A kind of addiction and heroinomania product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810734237.0A CN109077352A (en) | 2018-07-06 | 2018-07-06 | A kind of addiction and heroinomania product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109077352A true CN109077352A (en) | 2018-12-25 |
Family
ID=64837038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810734237.0A Pending CN109077352A (en) | 2018-07-06 | 2018-07-06 | A kind of addiction and heroinomania product |
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| Country | Link |
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| CN (1) | CN109077352A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113397163A (en) * | 2021-06-30 | 2021-09-17 | 魏道珍 | Product containing tetrahydropalmatine and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1392777A (en) * | 2000-12-11 | 2003-01-22 | 广州世纪珠玑实业发展有限公司 | Product containing tetiahydriopalmatime for curing opium-addiction and heroinomania and method for production thereof |
| CN103301760A (en) * | 2013-06-19 | 2013-09-18 | 徐志强 | Dissolving method of L-tetrahydropalmatine, L-tetrahydropalmatine solution and application of L-tetrahydropalmatine solution |
| CN108208925A (en) * | 2016-12-09 | 2018-06-29 | 金朝晖 | Anti-additive medicament containing anti-additive medicament sucks device, cigarette filter and cigarette |
-
2018
- 2018-07-06 CN CN201810734237.0A patent/CN109077352A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1392777A (en) * | 2000-12-11 | 2003-01-22 | 广州世纪珠玑实业发展有限公司 | Product containing tetiahydriopalmatime for curing opium-addiction and heroinomania and method for production thereof |
| CN103301760A (en) * | 2013-06-19 | 2013-09-18 | 徐志强 | Dissolving method of L-tetrahydropalmatine, L-tetrahydropalmatine solution and application of L-tetrahydropalmatine solution |
| CN108208925A (en) * | 2016-12-09 | 2018-06-29 | 金朝晖 | Anti-additive medicament containing anti-additive medicament sucks device, cigarette filter and cigarette |
Non-Patent Citations (2)
| Title |
|---|
| 原正平 等: "《化工产品手册 药物》", 31 December 1987 * |
| 马世昌 等: "《化学物质词典》", 30 April 1999 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113397163A (en) * | 2021-06-30 | 2021-09-17 | 魏道珍 | Product containing tetrahydropalmatine and preparation method and application thereof |
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Application publication date: 20181225 |
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