CN109011734A - A kind of device and method of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge - Google Patents

A kind of device and method of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge Download PDF

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Publication number
CN109011734A
CN109011734A CN201810948836.2A CN201810948836A CN109011734A CN 109011734 A CN109011734 A CN 109011734A CN 201810948836 A CN201810948836 A CN 201810948836A CN 109011734 A CN109011734 A CN 109011734A
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CN
China
Prior art keywords
alcohol
settling tank
chinese medicine
traditional chinese
automatic feed
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Pending
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CN201810948836.2A
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Chinese (zh)
Inventor
宋竹田
赵肖兵
金俊
缪晡
杨军
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Sinopec Engineering Group Co Ltd
Sinopec Shanghai Engineering Co Ltd
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Sinopec Engineering Group Co Ltd
Sinopec Shanghai Engineering Co Ltd
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Publication date
Application filed by Sinopec Engineering Group Co Ltd, Sinopec Shanghai Engineering Co Ltd filed Critical Sinopec Engineering Group Co Ltd
Priority to CN201810948836.2A priority Critical patent/CN109011734A/en
Publication of CN109011734A publication Critical patent/CN109011734A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/28Mechanical auxiliary equipment for acceleration of sedimentation, e.g. by vibrators or the like
    • B01D21/286Means for gentle agitation for enhancing flocculation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0006Settling tanks provided with means for cleaning and maintenance
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0012Settling tanks making use of filters, e.g. by floating layers of particulate material

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

The present invention relates to a kind of device and method of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge, including Alcohol-settling tank, blender and with the tank connected pipeline of alcohol precipitation and valve, described device further includes optical interface instrument, motor, discharging insertion tube, control system;The side of the Alcohol-settling tank is arranged in the motor, and the motor lower end is connected with the discharging insertion tube, and the inside of the Alcohol-settling tank is inserted into one end of the discharging insertion tube.It the advantage is that, Alcohol-settling tank is effectively cleaned by incumbent firms, avoids cross contamination, production is made to meet GMP standard;Using optical interface instrument, effectively identifies solid-liquid irregular interface in Alcohol-settling tank, solve the problems, such as that previous artificial judgment solid liquid interface is not allowed to lead to liquid waste, effectively improve production efficiency;Alcohol precipitation input and output material is controlled by control system, and operator need not be arranged in input and output material automation, alcohol precipitation workshop section scene, so that alcohol precipitation workshop section be allowed to automate, is unmanned, improves medical fluid extraction efficiency.

Description

A kind of device and method of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge
Technical field
The present invention relates to extracting technique of Chinese medicine technical field more particularly to a kind of dresses of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge It sets and method.
Background technique
Traditional Chinese medicine extraction is a link to Central Shanxi Plain medicine of Chinese medicine production, while being also restrict Chinese medicine industrialization development one A bottleneck.In traditional Chinese medicine extraction production, the degree of automation of alcohol precipitation workshop section by be traditional Chinese medicine extraction automation a key factor.
It is used currently, many traditional Chinese medicine extraction factories have been achieved with the workshop section that feeds intake, concentration section and drying section automation, still The automatic feed/discharge of alcohol precipitation workshop section is used as always a difficult point not broken through, always using manual operation, especially The medical fluid of alcohol precipitation discharges.In medical fluid discharging, need to go to judge that solid-liquid is irregular in Alcohol-settling tank by generally acknowledged naked eyes and feel Liquid level brings great inconvenience to Chinese medicine production, greatly reduces the efficiency of entire Chinese medicine production, causes unnecessary production The waste of medical fluid.
In numerous extracting technique of Chinese medicine, alcohol precipitation appears in most of Chinese medicines as a common Chinese medicine processing section In the extraction process of material.Traditional Chinese medicine extraction factory will not generally produce the drug of single variety, therefore the automatic feed/discharge of alcohol precipitation workshop section Process requirement have certain versatility and applicability, the needs of to meet existing product and the following new product.
Therefore, needing one kind can be realized alcohol precipitation automatic feed/discharge, effectively identification solid liquid interface, reduce liquid waste, alcohol The unmanned alcohol precipitation process of heavy workshop section, and roll had not been reported with this alcohol precipitation automatic feed/discharge technique at present.
Summary of the invention
The purpose of the present invention is aiming at the shortcomings in the prior art, provide a kind of dress of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge It sets and method.
To achieve the above object, the technical solution adopted by the present invention is that:
A kind of device of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge, including Alcohol-settling tank, blender and tank connected with alcohol precipitation Pipeline and valve, described device further include optical interface instrument, motor, discharging insertion tube, control system;
The top of the Alcohol-settling tank is arranged in the blender, and gos deep into the inside of the Alcohol-settling tank;
The top of the Alcohol-settling tank is arranged in the optical interface instrument;
The side of the Alcohol-settling tank is arranged in the motor, and the motor lower end is connected with the discharging insertion tube, The inside of the Alcohol-settling tank is inserted into one end of the discharging insertion tube;
The control system receives the optical interface instrument transmission for controlling the motor, the whip switch Data.
To advanced optimize above-mentioned apparatus, the concrete measure taken further include:
Described device further includes pump, and the pump is arranged on the pipeline connecting with the discharging insertion tube.
The pump is air driven pump.
Described device further includes stud filter, and the stud filter setting is connect with the discharging insertion tube (4) Pipeline on.
Described device further includes cleaning system.
The present invention also provides a kind of methods of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge, comprising the following steps:
Step S1, a certain amount of ethyl alcohol is passed through into Alcohol-settling tank;
Step S2, cool down to the ethyl alcohol in Alcohol-settling tank;
Step S3, after the completion of cooling, a certain amount of concentrate is passed through to Alcohol-settling tank;
Step S4, control system turn on agitator stirs the interior ethyl alcohol and concentrate of Alcohol-settling tank, mixes the two, After a certain period of time, control system closes blender, static for stirring;
Step S5, after the completion of stirring, using solid-liquid irregular interface in optical interface instrument identification Alcohol-settling tank, and number will be identified According to control system is transmitted to, control system opens motor, and control discharging insertion tube is rotated to clarified solution liquid level, control system Close motor;
Step S6, clarified solution is flowed out by discharging insertion tube from Alcohol-settling tank;
Step S7, after the completion of clarified solution discharge, bottom solid in Alcohol-settling tank is discharged;
Step S8, Alcohol-settling tank is cleaned.
To advanced optimize the above method, the concrete measure taken further include:
In above-mentioned steps S6, clarified solution is extracted out out of Alcohol-settling tank by pumping.
In above-mentioned steps S6, after Alcohol-settling tank outflow, clarified solution flows into the filtering of stud filter.
In above-mentioned steps S7, when clarified solution liquid level is lower than discharging insertion tube in Alcohol-settling tank, clarified solution outflow is completed.
In above-mentioned steps S8, Alcohol-settling tank and optical interface instrument are cleaned by cleaning system.
The invention adopts the above technical scheme, compared with prior art, has the following technical effect that
A kind of device and method of Chinese medicine alcohol precipitation automatic feed/discharge of the invention is not advised using optical interface instrument identification solid-liquid Identification data are transmitted to control system by then interface, and control system is according to identification situation, control motor rotation discharging insertion tube Position, the insertion tube that makes to discharge be in clarified solution, then is extracted clarified solution out out of Alcohol-settling tank with pumping, and is filtered through stud filter Into subsequent handling;Alcohol-settling tank is effectively cleaned by incumbent firms system, avoids cross contamination, production is made to meet drug Quality of production management regulation (GMP standard);Using optical interface instrument, solid-liquid irregular interface in Alcohol-settling tank is effectively identified, solve The problem of causing medical fluid unqualified or liquid waste is not allowed in previous artificial judgment solid liquid interface, effectively improves production efficiency;It is whole A alcohol precipitation input and output material is controlled by control system, automates input and output material, makes alcohol precipitation workshop section scene need not setting operator Member reduces human error so that alcohol precipitation workshop section be allowed to automate, is unmanned, improves medical fluid extraction efficiency.
Detailed description of the invention
Fig. 1 is the schematic diagram of a preferred embodiment of the present invention.
Appended drawing reference therein are as follows: Alcohol-settling tank 1;Blender 2;Optical interface instrument 3;Motor 4;Discharge insertion tube 5;Pump 6; Stud filter 7;Ethyl alcohol inlet valve 8;Low temperature water valve 9;Concentrate inlet valve 10;Clarified solution outlet valve 11;Purge valve 12;Compression Air inlet valve 13;Flowmeter 14;Flowmeter 15;Thermometer 16;Thermometer 17;Pressure gauge 18;Pressure gauge 19.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art without creative labor it is obtained it is all its His embodiment, shall fall within the protection scope of the present invention.
It should be noted that in the absence of conflict, the feature in embodiment and embodiment in the present invention can phase Mutually combination.
The present invention will be further explained below with reference to the attached drawings and specific examples, but not as the limitation of the invention.
Embodiment 1
As shown in Figure 1, a kind of device of preferred traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge of the invention, including Alcohol-settling tank 1, Blender 2, optical interface instrument 3, motor 4, discharging insertion tube 5, pump 6, stud filter 7, control system.
The setting of blender 2 is goed deep into inside Alcohol-settling tank 1 at 1 top of Alcohol-settling tank.The setting of optical interface instrument 3 is pushed up in Alcohol-settling tank 1 Portion.Motor 4 is arranged in 1 side of Alcohol-settling tank, and 4 lower end of motor is connected with discharging insertion tube 5, and one end of discharging insertion tube 5 is inserted Enter inside Alcohol-settling tank 1.Pump 6 is arranged on the pipeline connecting with discharging insertion tube 5.Stud filter 7, which is arranged in, to be connect with pump 6 On pipeline.
Alcohol-settling tank 1 is equipped with collet, ethyl alcohol import, concentrate import, Butterworth Hatch;Folder is set on outside Alcohol-settling tank 1, collet Equipped with low temperature water inlet, low temperature water out, low temperature water inlet is arranged on the downside of collet, and low temperature water out is arranged on the upside of collet; Ethyl alcohol import, concentrate import, Butterworth Hatch are separately positioned on 1 top of Alcohol-settling tank.
Ethyl alcohol inlet valve 8 is arranged on the pipeline connecting with ethyl alcohol import;The setting of low temperature water valve 9 connects with low temperature water out On the pipeline connect;Concentrate inlet valve 10 is arranged on the pipeline connecting with concentrate import;The setting of clarified solution outlet valve 11 exists On the pipeline being connect with discharging insertion tube 5;Purge valve 12 is arranged on the pipeline connecting with Butterworth Hatch.
Flowmeter 14 is provided on the pipeline connecting with ethyl alcohol import, flowmeter 14 is for controlling ethyl alcohol intake.
Flowmeter 15 is provided on the pipeline connecting with concentrate import, flowmeter 15 is passed through for controlling concentrate Amount.
Alcohol-settling tank 1 is provided with thermometer 16, and thermometer 16 is for controlling temperature in Alcohol-settling tank 1.
Thermometer 17 is provided on the pipeline connecting with low temperature water out, thermometer 17 is used to control the temperature of water at low temperature.
Pump 6 is provided with pressure gauge 18, and pressure gauge 18 is used to control the pressure of pump 6.
Stud filter 7 is provided with pressure gauge 19, and pressure gauge 19 is used to control the pressure in stud filter 7.
Pump 6 is air driven pump, and the pump 6 is provided with compressed air inlet pipeline, and pressure is provided on compressed air inlet pipeline Contracting air inlet valve 13.
Control system is switched for controlling all valves, motor 4, blender 2, receives the number that optical interface instrument 2 transmits According to.
Using the device of above-mentioned automatic feed/discharge, process flow is as follows:
Step S1, ethyl alcohol inlet valve 8 is opened, enters ethyl alcohol in Alcohol-settling tank 1 by the pipeline connecting with ethyl alcohol import, is led to Overcurrent meter 14 controls ethyl alcohol intake, when ethyl alcohol intake reaches setting value, closing ethyl alcohol inlet valve 8;
Step S2, low temperature water valve 9 is opened, water at low temperature is made to enter Alcohol-settling tank 1 by the pipeline connecting with low temperature water inlet In collet, and the pipeline by connecting with low temperature water out flows out, and opens blender 5, is stirred to ethyl alcohol, passes through thermometer The temperature of 17 pairs of water at low temperature controls;
Step S3, the temperature that ethyl alcohol in Alcohol-settling tank 1 is controlled by thermometer 16, when temperature reaches setting value, opening concentration Liquid inlet valve 10, makes concentrate enter Alcohol-settling tank 1 by the pipeline connecting with concentrate import, and concentrate intake reaches setting Value closes concentrate inlet valve 10;
Step S4, the interior ethyl alcohol and concentrate of Alcohol-settling tank (1) are stirred in control system turn on agitator (5), carry out the two Mixing, after a certain period of time, control system closes blender (5) for stirring, carries out static;
Step S5, solid-liquid irregular interface in Alcohol-settling tank 1 is identified using optical interface instrument 2, and send data to control System, control system open motor 3, and control discharging insertion tube 5 is rotated to clarified solution liquid level, and control system closes motor 3;
Step S6, clarified solution outlet valve 9 is opened, compressed air inlet valve 13 is opened, starting pump 6 is extracted by pump 6 and clarified Liquid flows out clarified solution from discharging insertion tube 5, and flows into stud filter 7;
Step S7, when clarified solution liquid level is lower than discharging insertion tube in Alcohol-settling tank 1, clarified solution outlet valve 9 is closed, pressure is closed Bottom solid in Alcohol-settling tank 1 is discharged in contracting air inlet valve 13, termination of pumping 6;
Step S8, purge valve 12 is opened, Alcohol-settling tank 1 and optical interface instrument 2 are cleaned by cleaning system;
Step S1-S8 is completed by automatic control system.
By adopting the above technical scheme, by utilizing optical interface instrument, it can effectively identify solid-liquid irregular interface, will identify Data are transmitted to control system, and control system makes to discharge according to identification situation, the position of control motor rotation discharging insertion tube Insertion tube is in clarified solution, then is extracted clarified solution out out of Alcohol-settling tank with pump, enters subsequent handling through the filtering of stud filter; Alcohol-settling tank is effectively cleaned by incumbent firms, avoids cross contamination, production is made to meet pharmaceutical production quality management practices (GMP standard);Using optical interface instrument, solid-liquid irregular interface in Alcohol-settling tank is effectively identified, it is solid to solve previous artificial judgment The problem of causing medical fluid unqualified or liquid waste is not allowed in liquid interface, effectively improves production efficiency;Entire alcohol precipitation input and output material by Control system is controlled, and input and output material is automated, make alcohol precipitation workshop section scene need not setting operator, to allow alcohol precipitation workshop section Automation, unmanned, reduction human error, raising medical fluid extraction efficiency.
In order to verify the reliability of above-mentioned apparatus practical application, present inventor has performed two groups of control experiments, as follows:
Experimental group 1
Certain uses the pharmaceutical factory of alcohol precipitation process, and Alcohol-settling tank is equipped with 48,5m3, using alcohol precipitation automatic feed/discharge of the invention Technique, alcohol precipitation area construction area be 540m2, and workshop section personnel are not provided in the workshop section that feeds intake.
Control group 1
Certain uses the pharmaceutical factory of alcohol precipitation process, and Alcohol-settling tank is equipped with 20,5m3, using the technique of traditional artificial control, alcohol Heavy area's construction area is 300m2, and 8 workshop section personnel are set in the workshop section that feeds intake.
Experimental group 1 and the comparing result of control group 1 are as follows:
Experimental group 1 Control group 1
Alcohol-settling tank quantity, platform 48 20
Alcohol precipitation tank volume, m3 5 5
Alcohol precipitation area construction area, m2 540 300
Workshop section personnel, name 0 8
Experimental group 1 and control group 1 are compared, it is found that using the device of automatic feed/discharge of the invention, land occupation Area is few, and workshop section personnel need not be arranged, and realizes that alcohol precipitation input and output material automates, is unmanned, reduction cost of labor, building cost, Be conducive to increase economic efficiency;It is controlled by control system, realizes precision, improve production efficiency, reduce liquid waste.
Experimental group 2
Certain uses the pharmaceutical factory of alcohol precipitation process, and Alcohol-settling tank is equipped with 4,5m3, using alcohol precipitation automatic feed/discharge of the invention Technique, alcohol precipitation area construction area are 40m2, and workshop section personnel are not provided in the workshop section that feeds intake.
Control group 2
Certain uses the pharmaceutical factory of alcohol precipitation process, and Alcohol-settling tank is equipped with 4,5m3, using traditional artificial technique, alcohol precipitation area Construction area is 45m2, and 3 workshop section personnel are set in the workshop section that feeds intake.Compared with Example 2, the side to be discharged using manual control Not only unit construction area Alcohol-settling tank quantity is few for formula, but also is equipped with 3 workshop section personnel, and cost of labor is higher than embodiment 2.
Experimental group 2 Control group 2
Alcohol-settling tank quantity, platform 4 4
Alcohol precipitation tank volume, m3 5 5
Alcohol precipitation area construction area, m2 40 45
Workshop section personnel, name 0 3
Through comparison it is found that in the case where identical Alcohol-settling tank quantity (5), using the dress of automatic feed/discharge of the invention It sets, occupied area is few, and workshop section personnel need not be arranged, and realizes that alcohol precipitation input and output material automates, is unmanned, reduces cost of labor, build This is built up, is conducive to increase economic efficiency;It is controlled by control system, realizes precision, improve production efficiency, reduce medical fluid wave Take.
The present invention can effectively identify that solid-liquid is irregular in Alcohol-settling tank by the way that an optical interface instrument is arranged at the top of Alcohol-settling tank Bounds, position of the accurate data control discharging insertion tube that control system is fed back by optical interface instrument in clarified solution, Ensure that the clarified solution flowed out without solid impurity, and ensures that clarified solution can utmostly flow out, previous artificial judgment is avoided to cause Discharging insertion tube excessive height waste medical fluid or the too low clarified solution of insertion tube height that discharges have the appearance of the problems such as impurity, favorably , automation unmanned in alcohol precipitation workshop section, high efficiency, advantageously reduce cost, improve benefit.
The foregoing is merely preferred embodiments of the present invention, are not intended to limit embodiments of the present invention and protection model It encloses, to those skilled in the art, should can appreciate that all with made by description of the invention and diagramatic content Equivalent replacement and obviously change obtained scheme, should all be included within the scope of the present invention.

Claims (10)

1. a kind of device of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge, including Alcohol-settling tank (1), blender (2) and with Alcohol-settling tank (1) The pipeline and valve of connection, which is characterized in that described device further includes optical interface instrument (3), motor (4), discharging insertion tube (5), control system;
Blender (2) setting is at the top of the Alcohol-settling tank (1), and it is internal to go deep into the Alcohol-settling tank (1);
Optical interface instrument (3) setting is at the top of the Alcohol-settling tank (1);
The motor (4) is arranged in the Alcohol-settling tank (1) side, and motor (4) lower end is connected with the discharging insertion It manages (5), it is internal that the Alcohol-settling tank (1) is inserted into one end of discharging insertion tube (5);
The control system receives the optical interface instrument (3) for controlling the motor (4), the blender (2) switch The data of transmission.
2. the device of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 1, which is characterized in that described device is also wrapped It includes pump (6), pump (6) setting is on the pipeline connecting with discharging insertion tube (5).
3. traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge system according to claim 2, which is characterized in that the pump (6) is gas Dynamic pump.
4. the device of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 1, which is characterized in that described device is also wrapped It includes stud filter (7), stud filter (7) setting is on the pipeline connecting with discharging insertion tube (5).
5. the device of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 1, which is characterized in that described device is also wrapped Include cleaning system.
6. a kind of method of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge, which comprises the following steps:
Step S1, a certain amount of ethyl alcohol is passed through into Alcohol-settling tank (1);
Step S2, cool down to the ethyl alcohol in Alcohol-settling tank (1);
Step S3, after the completion of cooling, a certain amount of concentrate is passed through to Alcohol-settling tank (1);
Step S4, the interior ethyl alcohol and concentrate of Alcohol-settling tank (1) are stirred in control system turn on agitator (2), mix the two It closes, after a certain period of time, control system closes blender (2) for stirring, carries out static;
Step S5, after the completion of static, Alcohol-settling tank (1) interior solid-liquid irregular interface is identified using optical interface instrument (3), and will identification Data are transmitted to control system, and control system opens motor (4), in control discharging insertion tube (5) rotation to clarified solution liquid level, Control system closes motor (4);
Step S6, clarified solution is flowed out by discharging insertion tube (5) from Alcohol-settling tank (1);
Step S7, after the completion of clarified solution outflow, Alcohol-settling tank (1) interior bottom solid is discharged;
Step S8, Alcohol-settling tank (1) and optical interface instrument (3) are cleaned.
7. the method for traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 6, which is characterized in that the step S6 In, pass through pump (6) extraction out of Alcohol-settling tank (1) by clarified solution.
8. the method for traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 6, which is characterized in that the step S6 In, after Alcohol-settling tank (1) outflow, clarified solution flows into stud filter (7) filtering.
9. the method for traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 6, which is characterized in that the step S7 In, when the interior clarified solution liquid level of Alcohol-settling tank (1) is lower than discharging insertion tube (5), clarified solution outflow is completed.
10. the method for traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge according to claim 6, which is characterized in that the step S8 In, Alcohol-settling tank (1) and optical interface instrument (3) are cleaned by cleaning system.
CN201810948836.2A 2018-08-20 2018-08-20 A kind of device and method of traditional Chinese medicine extraction alcohol precipitation automatic feed/discharge Pending CN109011734A (en)

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CN111569523A (en) * 2019-02-15 2020-08-25 天津天士力现代中药资源有限公司 Automatic control device for separation of traditional Chinese medicine alcohol precipitation liquid medicine

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Application publication date: 20181218