CN109010241A - A kind of medicinal shin moisturizer and preparation method thereof for repairing skin keratin - Google Patents

A kind of medicinal shin moisturizer and preparation method thereof for repairing skin keratin Download PDF

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Publication number
CN109010241A
CN109010241A CN201811295103.XA CN201811295103A CN109010241A CN 109010241 A CN109010241 A CN 109010241A CN 201811295103 A CN201811295103 A CN 201811295103A CN 109010241 A CN109010241 A CN 109010241A
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parts
medicinal
skin
shin moisturizer
weighed
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何翠英
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Zigong Leadman Technology Co Ltd
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Zigong Leadman Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

The invention belongs to a kind of medicinal shin moisturizer and preparation method thereof for repairing skin keratin, the medicinal shin moisturizer for repairing skin keratin is by including that the raw material of following parts by weight is made: 15-25 parts of grape seed extract, 2-4 parts of camomile extract, -1 3-4 parts of people's oligopeptides, 3-5 parts of glycerol, 10-15 parts of vitamin e, 3-7 parts, -3 parts of Cer EOS of salmon ovary peptide, 1-2 parts of Sodium Hyaluronate, 30-40 parts of deionized water, 5-10 parts of dipotassium glycyrrhizinate, 0.5-1 parts of menthol, 2-3 parts of Rosa Damascana.Each raw material proportioning is suitable in the present invention, the superior stabilization of the selected quality of the pharmaceutical preparations, can go deep into skin depths rapidly, promotes cell division regeneration, and activated cell vigor repairs skin keratin elasticity, makes fragile muscle and skin white light sliding, compact seamless, restores as before.

Description

A kind of medicinal shin moisturizer and preparation method thereof for repairing skin keratin
Technical field
The invention belongs to medicines and health protection fields, and in particular to it is a kind of repair skin keratin medicinal shin moisturizer and its preparation side Method.
Background technique
Red capillary, which is primarily due to facial cuticula weakness, causes capillary position to be easier to contact and perceive the external world Environmental change, to cause face phenomenon caused by telangiectasias.Red blood trace on face patient facial region seems than general Normal skin tone is red.People often claim plateau face or blush egg or rotten apple, and some is only that cheekbone portion in two sides is rubescent, and boundary is in circle Shape, generally in silk the linear alignment.This skin is thin and sensitive, and face is redder when being subcooled, overheating, is excited.Serious person can also Form deposition color spot, it is difficult to cure, it is thinning to eventually lead to keratoderma.
In the existing technical method for repairing keratoderma, using the methods of nutrient laden, moisturizing, prevent skin keratin into One step is thinning, the starting for the reconstruction cell for waiting skin own, the mode of self-healing;It is slow but there are recovery effects, effect Bad, slow effect, the defects of easily rebound, and there are certain dependences to act on for some reparation product, and safety in utilization is poor, limits Repair the development and application of product.Therefore developing the new and effective medicinal shin moisturizer for repairing cortical layer has great significance.
Summary of the invention
The present invention provides a kind of medicinal shin moisturizer and preparation method thereof for repairing skin keratin, need from clinical treatment medication It asks and dialectical principle is set out, the superior stabilization of the selected quality of the pharmaceutical preparations, proportion precisely, can go deep into rapidly skin depths, promote thin Born of the same parents divide regeneration, and activated cell vigor repairs skin keratin elasticity, makes fragile muscle and skin white light sliding, compact seamless, restore as before.
To solve existing technical problem, The technical solution adopted by the invention is as follows:
A kind of medicinal shin moisturizer for repairing skin keratin, the medicinal shin moisturizer for repairing skin keratin is by including following heavy The raw material of amount number is made: 15-25 parts of grape seed extract, 2-4 parts of camomile extract, -1 3-4 parts of people's oligopeptides, glycerol 3-5 Part, 10-15 parts of vitamin e, 3-7 parts of salmon ovary peptide, -3 parts of Cer EOS, 1-2 parts of Sodium Hyaluronate, deionized water 30- 40 parts, 5-10 parts of dipotassium glycyrrhizinate, 0.5-1 parts of menthol, 2-3 parts of Rosa Damascana.
Preferably, the medicinal shin moisturizer for repairing skin keratin is by including that the raw material of following parts by weight is made: grape 17-23 parts of seed extract, 3-4 parts of camomile extract, -1 3-4 parts of people's oligopeptides, 4-5 parts of glycerol, 11-14 parts of vitamin e, salmon 4-6 parts of fish ovaries peptide, -2 parts of Cer EOS, 1-2 parts of Sodium Hyaluronate, 35-40 parts of deionized water, 6-9 parts of dipotassium glycyrrhizinate, 0.5-1 parts of menthol, 1-2 parts of Rosa Damascana.
Preferably, the medicinal shin moisturizer for repairing skin keratin is by including that the raw material of following parts by weight is made: grape 20 parts of seed extract, 3 parts of camomile extract, -1 3.5 part of people's oligopeptides, 4 parts of glycerol, 12.5 parts of vitamin e, salmon ovary peptide 5 parts, Cer NS part, 1.5 parts of Sodium Hyaluronate, 35 parts of deionized water, 7.5 parts of dipotassium glycyrrhizinate, 0.75 part of menthol, rose 2.5 parts of rare essential oil.
It is a kind of repair skin keratin medicinal shin moisturizer production method the following steps are included:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In several grape seed extracts, 1-4 hour is at the uniform velocity stirred, is filtered by vacuum, is stood;
(2) weighed people's oligopeptides -1, glycerol are dissolved in the grape of remaining 50% parts by weight under the pressure of 0.5MPa In seed extract, 2-4 hour is at the uniform velocity stirred, is filtered by vacuum, is stood;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), in the pressure of 0.6MPa Under, it at the uniform velocity stirs 5-7 hours, temperature is controlled at 20-30 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, dimension is then added He orders E and ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continues stirring 0.5-2 hours until completely molten Solution, obtains solution A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, side stirring Solution A is added in side, under the pressure of 0.3MPa, stirs 3.5-4 hours at the uniform velocity to get the medicinal skin care for repairing skin keratin Liquid.
Grape seed extract is pure natural substance, is one of the most efficient antioxidant of plant origin found so far, examination It tests and shows 30~50 times that its antioxidant effect is vitamin C and vitamin E.Procyanidine has extremely strong activity, can inhibit Carcinogenic substance in cigarette is 2~7 times of general antioxidant to the capturing ability of free radical in water phase, such as than alpha-tocopherol Activity high twice or more.
Camomile extract is also popular health protection and drug system by the chamomile essential oil that chamomile extract Product.Because chamomile can help for sleep, alleviate inflammation and the pain symptom of patient, alleviates as caused by neurotic skin itch The effect of insomnia.Selected areas of China, which also has, is largely cultivating, to be used as medicine and tea making.
EGF (people's oligopeptides -1) is made of 53 amino acid, and the polypeptide including 3 disulfide bond.The molecular weight of EGF precursor is 130KD, volume ratio bacterium also want 300 times small, and the EGF gene of people is located at the long-armed of No. 4 chromosomes.EGF can promote cell Proliferation, Differentiation, to replace the process of senile cell and dead cell with neonatal cell.What Traditional makeup rose is outside modification Effect, cannot fundamentally solve skin problem, and it is physiology knot according to human skin in cosmetics that EGF, which is applied, Structure is repaired and is adjusted to cell on a molecular scale.
Glycerol, the higher glycerol of purity, quality is pure, uses after being watered, and moisturizing effect is very good, is moistened with rear water water The soft skin of profit touches up very comfortable.But partial glycerol needs first to try out down before use, with hypo-allergenic because purity is higher. In addition, the bleeding if skin has cracked, cannot use pure glycerin.Because glycerol is that moisturizing is used, it is used in affected part, is held Easily cause to infect.
Vitamin E is a kind of liposoluble vitamin, and it is one of most important antioxidant that hydrolysate, which is tocopherol,. It is dissolved in the organic solvents such as fat and ethyl alcohol, it is not soluble in water, heat, acid are stablized, it is unstable to alkali, it is sensitive to oxygen, it is unwise to heat Sense.Increase woman's female hormone concentration, improve fecundity, prevention of miscarriage, it may also be used for prevention and treatment male sterility, burn, Frostbite, capillary hemorrhage, climacteric syndrome, beauty etc..Recently it has also been found that vitamin E can inhibit in ocular lens body Lipid peroxidation reaction, make peripheral vasodilation, improve blood circulation, pre- Anti-myopic eye occurrence and development.
Salmon ovary beautifying liquid possesses fish-egg extract, and nutritional ingredient needed for having accumulated numerous human skin growths connects Touch skin effective component moment through skin corium.Skin is the most vigorous organ of body metabolism, needs the benefit of multiple nutritional components It fills to help skin metabolism.Therefore salmon ovary beautifying liquid can effectively help the old dead, non-viable non-apoptotic cell for being metabolized human skin, Rest cell is activated, skin texture is helped to reform, supplements skin collagen, human skin resistance is quickly and effectively helped to decline Always, while skin damage cell and water lock system are repaired in effective component help, maintain the lasting water profit of skin, human body is allowed to return to blueness Spring vigor state reaches real anti-ageing effect at all from human body, is kept for the permanent youth.
Ceramide forms sphingoin matter one kind by sphingosine long chain base and fatty acid.Ceramide is Using ceramide as a kind of phosphatide of skeleton, mainly there are ceramide phosphocholine and ceramide phosphoethanolamine, phosphatide is The main component of cell membrane, 40%~50% sebum is made of ceramide in cuticula, and ceramide is intercellular matrix Major part, keep cuticula moisture balance in play an important role.
Sodium hyaluronate, scientific name hyaluronic acid.Sodium hyaluronate is the colloid substance of transparent tool stickiness, and sodium hyaluronate is a kind of macromolecule Polysaccharide body, be the straight chain polymer polysaccharide that forms of disaccharide molecular unit by glucuronic acid-N- acetic acid Glucosamine, it is average Molecular weight is just filled in cell and collagenous fibres in the skin histology of human body originally between 10 ten thousand to 200 ten thousand dalton Space in.Sodium hyaluronate, which not only has, keeps skin elasticity function, moreover it is possible to lock a large number of water molecules, there is moisturizing lubrication to make tissue With keeping the full youth of skin flexible, but once with aging and the growth at age, it is faster than the speed of growth that sodium hyaluronate is lost speed When, skin will also become to lack moisture gradually, and tarnish elasticity, gets off just to occur the aging phenomena such as wrinkle for a long time.
Dipotassium glycyrrhizinate is white or off-white color fine powder, and purity has a special sweet taste up to 98%, it is water-soluble it is good, mouthfeel is pure.It is sweet Oxalic acid dipotassium has the multiple efficacies such as antibacterial, anti-inflammatory, removing toxic substances, antiallergic, deodorization.Have in the industries such as medicine, cosmetics daily use chemicals, food It is widely applied.
Menthol, organic compound, colorless needle crystals or granular.For the main component in peppermint and lavender essential oil, Exist with free and ester state.It can be used as the odorant of toothpaste, perfume, beverage and candy etc..It is used as excitants in medicine, Skin or mucous membrane are acted on, there is refrigerant itching-relieving action;It is for oral administration to can be used for headache and nose, pharynx, laryngitis etc.
Rosa Damascana is the essential oil of most expensive in the world, referred to as " after essential oil ".Female incretion can be adjusted, son is nourished Dysmenorrhea is alleviated in palace, improves frigidity and climacteric is uncomfortable.Especially there is good beautifying skin-protection function, supported within energy outer light Change spot, melanin is promoted to decompose, improve dry skin, restore skin elasticity, women is allowed to possess health pale, full of elasticity Skin is the volatile oil for being suitable for female health.
In conclusion compared with the prior art, the invention has the advantages that: produced by the present invention repair skin keratin Medicinal shin moisturizer can promote the new life of cell, realize the reconstruction of skin histology, can significantly improve the defence energy of skin Power, and there is anti-acne, moisturizing, whitening and anti-aging, antibacterial, anti-inflammatory effect;Promote skin metabolism, toxin-expelling and face nourishing, bright color The effect of obvious, maintenance skin, keep the pure and fresh smooth pleasant sense of skin;Promote Skin Cell regeneration;It repairs skin, make skin Restore as before, smooth compact;Curative for effect, medicinal effects are significant, are suitable for promoting the use of.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not used to limit The fixed present invention, i.e., described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Therefore, the detailed description of the embodiment of the present invention presented below is not intended to limit claimed invention Range, but it is merely representative of selected embodiment of the invention.Based on the embodiment of the present invention, those skilled in the art are not doing Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.
Embodiment 1
A kind of medicinal shin moisturizer of reparation skin keratin described in the present embodiment, the medicinal skin care for repairing skin keratin Liquid by include following parts by weight raw material be made: 15 parts of grape seed extract, 2 parts of camomile extract, -1 3 part of people's oligopeptides, 3 parts of glycerol, 10 parts of vitamin e, 3 parts of salmon ovary peptide, Cer EOS part, it is 1 part of Sodium Hyaluronate, 30 parts of deionized water, sweet 5 parts of oxalic acid dipotassium, 0.5 part of menthol, 2 parts of Rosa Damascana.
It is a kind of repair skin keratin medicinal shin moisturizer production method the following steps are included:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In several grape seed extracts, 1 hour is at the uniform velocity stirred, is filtered by vacuum, is stood;
(2) weighed people's oligopeptides -1, glycerol are dissolved in the grape of remaining 50% parts by weight under the pressure of 0.5MPa In seed extract, 4 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), in the pressure of 0.6MPa Under, it at the uniform velocity stirs 5 hours, temperature is controlled at 30 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, vitamin e is then added With ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continue stirring 0.5 hour until being completely dissolved, obtain solution A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, side stirring Solution A is added in side, under the pressure of 0.3MPa, stirs 3.5 hours at the uniform velocity to get the medicinal skin care for repairing skin keratin Liquid.
Embodiment 2
A kind of medicinal shin moisturizer of reparation skin keratin described in the present embodiment, the medicinal skin care for repairing skin keratin Liquid by include following parts by weight raw material be made: 25 parts of grape seed extract, 4 parts of camomile extract, -1 4 part of people's oligopeptides, 5 parts of glycerol, 15 parts of vitamin e, 7 parts of salmon ovary peptide, Cer NP part, it is 2 parts of Sodium Hyaluronate, 40 parts of deionized water, sweet 10 parts of oxalic acid dipotassium, 1 part of menthol, 3 parts of Rosa Damascana.
It is a kind of repair skin keratin medicinal shin moisturizer production method the following steps are included:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In several grape seed extracts, 4 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(2) weighed people's oligopeptides -1, glycerol are dissolved in the grape of remaining 50% parts by weight under the pressure of 0.5MPa In seed extract, 4 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), in the pressure of 0.6MPa Under, it at the uniform velocity stirs 7 hours, temperature is controlled at 20 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, vitamin e is then added With ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continue stirring 2 hours until being completely dissolved, obtain solution A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, side stirring Solution A is added in side, under the pressure of 0.3MPa, stirs 4 hours at the uniform velocity to get the medicinal shin moisturizer for repairing skin keratin.
Embodiment 3
A kind of medicinal shin moisturizer of reparation skin keratin described in the present embodiment, the medicinal skin care for repairing skin keratin Liquid by include following parts by weight raw material be made: 17 parts of grape seed extract, 3 parts of camomile extract, -1 3 part of people's oligopeptides, 4 parts of glycerol, 11 parts of vitamin e, 4 parts of salmon ovary peptide, Cer EOS part, it is 1 part of Sodium Hyaluronate, 35 parts of deionized water, sweet 6 parts of oxalic acid dipotassium, 0.5 part of menthol, 1 part of Rosa Damascana.
The production method of the medicinal shin moisturizer of above-mentioned reparation skin keratin a kind of the following steps are included:
It is a kind of repair skin keratin medicinal shin moisturizer production method the following steps are included:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In several grape seed extracts, 1 hour is at the uniform velocity stirred, is filtered by vacuum, is stood;
(2) weighed people's oligopeptides -1, glycerol are dissolved in the grape of remaining 50% parts by weight under the pressure of 0.5MPa In seed extract, 2 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), in the pressure of 0.6MPa Under, it at the uniform velocity stirs 5 hours, temperature is controlled at 30 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, vitamin e is then added With ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continue stirring 0.5 hour until being completely dissolved, obtain solution A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, side stirring Solution A is added in side, under the pressure of 0.3MPa, stirs 3.5 hours at the uniform velocity to get the medicinal skin care for repairing skin keratin Liquid.
Embodiment 4
A kind of medicinal shin moisturizer of reparation skin keratin described in the present embodiment, the medicinal skin care for repairing skin keratin Liquid by include following parts by weight raw material be made: 23 parts of grape seed extract, 4 parts of camomile extract, -14 parts of people's oligopeptides, 5 parts of glycerol, 14 parts of vitamin e, 6 parts of salmon ovary peptide, Cer NS part, it is 2 parts of Sodium Hyaluronate, 40 parts of deionized water, sweet 9 parts of oxalic acid dipotassium, 1 part of menthol, 2 parts of Rosa Damascana.
It is a kind of repair skin keratin medicinal shin moisturizer production method the following steps are included:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In several grape seed extracts, 4 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(2) weighed people's oligopeptides -1, glycerol are dissolved in the grape of remaining 50% parts by weight under the pressure of 0.5MPa In seed extract, 4 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), in the pressure of 0.6MPa Under, it at the uniform velocity stirs 7 hours, temperature is controlled at 20 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, vitamin e is then added With ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continue stirring 2 hours until being completely dissolved, obtain solution A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, side stirring Solution A is added in side, under the pressure of 0.3MPa, stirs 4 hours at the uniform velocity to get the medicinal shin moisturizer for repairing skin keratin.
Embodiment 5
A kind of medicinal shin moisturizer of reparation skin keratin described in the present embodiment, the medicinal skin care for repairing skin keratin Liquid is by including that the raw material of following parts by weight is made: 20 parts of grape seed extract, 3 parts of camomile extract, people's oligopeptides -1 3.5 Part, 4 parts of glycerol, 12.5 parts of vitamin e, 5 parts of salmon ovary peptide, Cer NS part, 1.5 parts of Sodium Hyaluronate, deionized water 35 parts, 7.5 parts of dipotassium glycyrrhizinate, 0.75 part of menthol, 2.5 parts of Rosa Damascana.
It is a kind of repair skin keratin medicinal shin moisturizer production method the following steps are included:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In several grape seed extracts, 2.5 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(2) weighed people's oligopeptides -1, glycerol are dissolved in the grape of remaining 50% parts by weight under the pressure of 0.5MPa In seed extract, 3 hours are at the uniform velocity stirred, are filtered by vacuum, are stood;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), in the pressure of 0.6MPa Under, it at the uniform velocity stirs 6 hours, temperature is controlled at 25 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, vitamin e is then added With ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continue stirring 1.25 hours until being completely dissolved, obtain molten Liquid A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, side stirring Solution A is added in side, under the pressure of 0.3MPa, stirs 3.75 hours at the uniform velocity to get the medicinal skin care for repairing skin keratin Liquid.
The specific embodiment of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously The limitation to the application protection scope therefore cannot be interpreted as.It should be pointed out that for those of ordinary skill in the art For, under the premise of not departing from technical scheme design, various modifications and improvements can be made, these belong to this The protection scope of application.

Claims (4)

1. it is a kind of repair skin keratin medicinal shin moisturizer, it is characterised in that: it is described repair skin keratin medicinal shin moisturizer by Raw material including following parts by weight is made: 15-25 parts of grape seed extract, 2-4 parts of camomile extract, -1 3-4 of people's oligopeptides Part, 3-5 parts of glycerol, 10-15 parts of vitamin e, 3-7 parts of salmon ovary peptide, -3 parts of Cer EOS, 1-2 parts of Sodium Hyaluronate are gone 30-40 parts of ionized water, 5-10 parts of dipotassium glycyrrhizinate, 0.5-1 parts of menthol, 2-3 parts of Rosa Damascana.
2. a kind of medicinal shin moisturizer for repairing skin keratin according to claim 1, it is characterised in that: the reparation skin The medicinal shin moisturizer of cutin is by including that the raw material of following parts by weight is made: 17-23 parts of grape seed extract, camomile extract 3-4 parts, -1 3-4 parts of people's oligopeptides, 4-5 parts of glycerol, 11-14 parts of vitamin e, 4-6 parts of salmon ovary peptide, -2 parts of Cer EOS, 1-2 parts of Sodium Hyaluronate, 35-40 parts of deionized water, 6-9 parts of dipotassium glycyrrhizinate, 0.5-1 parts of menthol, 1-2 parts of Rosa Damascana.
3. a kind of medicinal shin moisturizer for repairing skin keratin according to claim 2, it is characterised in that: the reparation skin The medicinal shin moisturizer of cutin is by including that the raw material of following parts by weight is made: 20 parts of grape seed extract, camomile extract 3 Part, -1 3.5 part of people's oligopeptides, 4 parts of glycerol, 12.5 parts of vitamin e, 5 parts of salmon ovary peptide, Cer NS part, Sodium Hyaluronate 1.5 parts, 35 parts of deionized water, 7.5 parts of dipotassium glycyrrhizinate, 0.75 part of menthol, 2.5 parts of Rosa Damascana.
4. a kind of preparation method of the described in any item medicinal shin moisturizer for repairing skin keratin of claims 1 to 3, feature exist In, comprising the following steps:
(1) weighed camomile extract, Rosa Damascana, menthol are dissolved in 50% parts by weight under the pressure of 0.6MPa In grape seed extract, 1-4 hour is at the uniform velocity stirred, is filtered by vacuum, is stood;
(2) grape pip that weighed people's oligopeptides -1, glycerol are dissolved in remaining 50% parts by weight under the pressure of 0.5MPa is mentioned It takes in object, at the uniform velocity stirs 2-4 hour, be filtered by vacuum, stand;
(3) solution obtained in step (1) is mixed with solution obtained in step (2), it is even under the pressure of 0.6MPa Speed stirring 5-7 hours, temperature is controlled at 20-30 DEG C, merges it sufficiently, weighed Sodium Hyaluronate, vitamin e is then added With ceramide, stirring 1 hour, adds weighed salmon ovary peptide and continue stirring 0.5-2 hours until being completely dissolved, obtain molten Liquid A;
(4) weighed dipotassium glycyrrhizinate is dissolved in weighed deionized water under the pressure of 0.6MPa, then, while stirring plus Enter solution A, under the pressure of 0.3MPa, stirs 3.5-4 hours at the uniform velocity to get the medicinal shin moisturizer for repairing skin keratin.
CN201811295103.XA 2018-11-01 2018-11-01 A kind of medicinal shin moisturizer and preparation method thereof for repairing skin keratin Pending CN109010241A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110179718A (en) * 2019-07-03 2019-08-30 广东巴松那生物科技有限公司 A kind of anthosin droplet dew for purifying skin of refreshing oneself and preparation method thereof
CN111658573A (en) * 2020-06-17 2020-09-15 广州艾尔亿医药有限公司 Human-like serum protein preparation for regenerative medicine cosmetology
CN113876673A (en) * 2021-08-27 2022-01-04 江苏苏美国际时尚管理有限公司 Mask capable of repairing cuticle

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110179718A (en) * 2019-07-03 2019-08-30 广东巴松那生物科技有限公司 A kind of anthosin droplet dew for purifying skin of refreshing oneself and preparation method thereof
CN111658573A (en) * 2020-06-17 2020-09-15 广州艾尔亿医药有限公司 Human-like serum protein preparation for regenerative medicine cosmetology
CN113876673A (en) * 2021-08-27 2022-01-04 江苏苏美国际时尚管理有限公司 Mask capable of repairing cuticle

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Application publication date: 20181218