CN109001468A - A kind of detection kit of CMV antibody IgM - Google Patents
A kind of detection kit of CMV antibody IgM Download PDFInfo
- Publication number
- CN109001468A CN109001468A CN201810883445.7A CN201810883445A CN109001468A CN 109001468 A CN109001468 A CN 109001468A CN 201810883445 A CN201810883445 A CN 201810883445A CN 109001468 A CN109001468 A CN 109001468A
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- added
- calibration object
- microballon
- reagent
- herpes simplex
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- 238000001514 detection method Methods 0.000 title claims abstract description 32
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 28
- 239000000427 antigen Substances 0.000 claims abstract description 27
- 102000036639 antigens Human genes 0.000 claims abstract description 27
- 108091007433 antigens Proteins 0.000 claims abstract description 27
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 241000701022 Cytomegalovirus Species 0.000 claims abstract description 19
- 239000000243 solution Substances 0.000 claims abstract description 18
- 238000004140 cleaning Methods 0.000 claims abstract description 17
- 241000223996 Toxoplasma Species 0.000 claims abstract description 14
- 239000011325 microbead Substances 0.000 claims abstract description 14
- 241000701074 Human alphaherpesvirus 2 Species 0.000 claims abstract description 11
- 239000000725 suspension Substances 0.000 claims abstract description 10
- 239000012898 sample dilution Substances 0.000 claims abstract description 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 7
- 239000004005 microsphere Substances 0.000 claims abstract description 7
- 238000005516 engineering process Methods 0.000 claims abstract description 6
- 230000004913 activation Effects 0.000 claims abstract description 5
- 239000011248 coating agent Substances 0.000 claims abstract description 5
- 238000000576 coating method Methods 0.000 claims abstract description 5
- 238000004519 manufacturing process Methods 0.000 claims abstract description 5
- 239000003550 marker Substances 0.000 claims abstract description 5
- 239000013558 reference substance Substances 0.000 claims abstract description 5
- 229910019142 PO4 Inorganic materials 0.000 claims description 6
- 241001494479 Pecora Species 0.000 claims description 6
- 108010004729 Phycoerythrin Proteins 0.000 claims description 6
- 239000004793 Polystyrene Substances 0.000 claims description 6
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- 239000000872 buffer Substances 0.000 claims description 6
- 239000012895 dilution Substances 0.000 claims description 6
- 238000010790 dilution Methods 0.000 claims description 6
- 239000004615 ingredient Substances 0.000 claims description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 6
- 239000010452 phosphate Substances 0.000 claims description 6
- 229920002223 polystyrene Polymers 0.000 claims description 6
- 239000000470 constituent Substances 0.000 claims description 5
- 238000005406 washing Methods 0.000 claims description 5
- 241000700584 Simplexvirus Species 0.000 claims description 4
- 239000007836 KH2PO4 Substances 0.000 claims description 3
- 229920001213 Polysorbate 20 Polymers 0.000 claims description 3
- 239000007983 Tris buffer Substances 0.000 claims description 3
- 239000012470 diluted sample Substances 0.000 claims description 3
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims description 3
- 235000019796 monopotassium phosphate Nutrition 0.000 claims description 3
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims description 3
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims description 3
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims description 3
- 201000005404 rubella Diseases 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- 238000003860 storage Methods 0.000 claims description 3
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims description 3
- 238000002604 ultrasonography Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000012224 working solution Substances 0.000 claims description 3
- CCMKPCBRNXKTKV-UHFFFAOYSA-N 1-hydroxy-5-sulfanylidenepyrrolidin-2-one Chemical compound ON1C(=O)CCC1=S CCMKPCBRNXKTKV-UHFFFAOYSA-N 0.000 claims 1
- -1 3- dimethylaminopropyl Chemical group 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
- 241000700588 Human alphaherpesvirus 1 Species 0.000 abstract description 9
- 239000000523 sample Substances 0.000 description 4
- 241000700605 Viruses Species 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 238000003908 quality control method Methods 0.000 description 2
- 208000010201 Exanthema Diseases 0.000 description 1
- 241000175212 Herpesvirales Species 0.000 description 1
- 241000710799 Rubella virus Species 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56994—Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a kind of detection kits of the antibody IgMs such as cytomegalovirus, belong to detection reagent technical field.It includes compounded microbeads suspension, fluorescence display agent, Sample dilution and cleaning solution, production technology saves liquid according to microballon is prepared, the activation and coating of microballoon, it prepares fluorescent marker and prepares concentrated cleaning solution and produced, and combine calibration object 1, calibration object 2, calibration object 3, the specific antigen of reference microspheres and NSC microballoon reference substance, it solves when the toxoplasma in one sample of detection, rubeola, when cytomegalovirus and herpes simplex virus type 1 and herpes simplex virus type 2, it needs individually with four kinds of detection reagents respectively to toxoplasma, rubeola, cytomegalovirus, the problem of herpes simplex virus type 1 and herpes simplex virus type 2 are detected, shorten detection time, to improve detection efficiency.
Description
Technical field
The present invention relates to a kind of detection kits of the antibody IgMs such as cytomegalovirus, belong to detection reagent technical field, this
Invention is that one kind can be in a micropore, while measuring the toxoplasma in a sample, rubella virus, and cytomegalovirus is single
Pure 1 type of herpesviral, the detection kit of herpes simplex virus type 2 IgM antibody.
Background technique
Toxoplasma, rubeola, cytomegalovirus, herpes simplex virus type 1, herpes simplex virus type 2 are that today's society is common
Virus, however as the progress of medical level, toxoplasma, rubeola, cytomegalovirus and herpes simplex virus type 1 and simple blister
2 type of exanthema virus can be transferred through existing detection reagent and be detected, and then do further treatment again, however when one sample of detection
When toxoplasma, rubeola, cytomegalovirus and herpes simplex virus type 1 and herpes simplex virus type 2 in this, need individually to use
Four kinds of detection reagents respectively to toxoplasma, rubeola, cytomegalovirus and herpes simplex virus type 1 and herpes simplex virus type 2 into
Row detection, increases detection time, reduces detection efficiency.
Summary of the invention
Technical problem to be solved by the present invention lies in: a kind of detection kit of the antibody IgMs such as cytomegalovirus is provided,
It is solved when toxoplasma, rubeola, cytomegalovirus, herpes simplex virus type 1 and the herpe simplex disease in one sample of detection
When malicious 2 type, need individually with four kinds of detection reagents respectively to toxoplasma, rubeola, cytomegalovirus, herpes simplex virus type 1
The problem of being detected with herpes simplex virus type 2.
The technical problems to be solved by the invention take following technical scheme to realize:
A kind of detection kit of the antibody IgMs such as cytomegalovirus, detection kit includes compounded microbeads suspension, fluorescence display
Agent, Sample dilution and cleaning solution,
(1) compounded microbeads suspension: including cognizable polystyrene microbeads in suspension, and polystyrene microbeads are coated with respectively
There is following antigen: toxoplasma antigen, rubella antigens, big and small extracellular antigen, -1 antigen of herpes simplex virus and herpes simplex virus-2
Antigen;
(2) fluorescence display agent: the sheep Anti-Human's IgM(specificity γ marked using the phycoerythrin that initial concentration is 1.0 ug/mL
Chain), dilution calibration is working solution concentration 0.6ug/mL, 2-8 DEG C of storage;
(3) Sample dilution: phosphate-containing buffer is used for diluted sample;
(4) cleaning solution: phosphate-containing buffer need to be used with 10 times of purified water dilutions, board-washing.
As preferred embodiment, the production technology of kit mainly has the following steps:
1. preparing microballon saves liquid, microballon saves the NaCl reagent that liquid main component includes: i.e. 8.0g/L, 2.9g/L's
Na2HPO412H2O reagent, the KCl reagent of 2.4g/L, the KH2PO4 reagent of 2.4g/L, the Tris reagent of 0.5g/L, 0.5mL/
The Tween20 reagent of L, the Sodium Azide reagent of 0.5g/L.
2. the activation and coating of microballoon take 1mL particular number microballon that 1.5mL centrifuge tube is added, 5-50uL EDC(1- second is added
Base-(3- dimethylaminopropyl) phosphinylidyne diimmonium salt hydrochlorate) and 5-50uL SuLfo-NHS(N- hydroxy succinyl Asia
Amine), 10-100ug specific antigen is added, is vortexed and mixes 30 seconds, ultrasound mixes 30 seconds, and 2-8 DEG C shakes up overnight.
3. fluorescent marker: the sheep Anti-Human IgM(specificity γ chain of phycoerythrin label), 1 μ g/mL of initial concentration, use is micro-
Pearl saves liquid and is diluted to working concentration, and working concentration is 0.6 μ g/L.
4. concentrated cleaning solution: it is consistent to save the ingredient of liquid for ingredient and microballon in concentrated cleaning solution, and concentrated cleaning solution respectively at
Dividing concentration is 10 times that microballon saves each constituent concentration of liquid.
As preferred embodiment, specific antigen includes calibration object 1, calibration object 2, calibration object 3, reference microspheres and NSC microballoon reference substance,
The people IgM of 2-5ug/mL is added in calibration object 1, and the people IgM of 6-10ug/mL is added in calibration object 2, and 12-18ug/mL is added in calibration object 3
People IgM, reference microspheres be added 8-15ug/mL anti-human IgM, NSC microballoon as control, be added without any antigen.
The beneficial effects of the present invention are: the present invention includes compounded microbeads suspension, fluorescence display agent, Sample dilution and washes
Liquid is washed, production technology saves liquid, the activation of microballoon and coating, prepares fluorescent marker and prepare thickening and washing according to microballon is prepared
Liquid is produced, and combine calibration object 1, calibration object 2, calibration object 3, reference microspheres and NSC microballoon reference substance specific antigen, solution
It has determined when detecting the toxoplasma in a sample, rubeola, cytomegalovirus and herpes simplex virus, has needed individually with four kinds
Detection reagent respectively examines toxoplasma, rubeola, cytomegalovirus and herpes simplex virus type 1 and herpes simplex virus type 2
The problem of survey, shortens detection time, to improve detection efficiency.
Specific embodiment
In order to be easy to understand to technical means, creative features, achievable purpose and effectiveness of the invention, below with reference to tool
Body embodiment, the present invention is further explained.
A kind of detection kit of the antibody IgMs such as cytomegalovirus, detection kit includes compounded microbeads suspension, fluorescence
Developer, Sample dilution and cleaning solution,
(1) compounded microbeads suspension: including cognizable polystyrene microbeads in suspension, and polystyrene microbeads are coated with respectively
There is following antigen: toxoplasma antigen, rubella antigens, big and small extracellular antigen, -1 antigen of herpes simplex virus and herpes simplex virus-2
Antigen;
(2) fluorescence display agent: the sheep Anti-Human's IgM(specificity γ marked using the phycoerythrin that initial concentration is 1.0 ug/mL
Chain), dilution calibration is working solution concentration 0.6ug/mL, 2-8 DEG C of storage;
(3) Sample dilution: phosphate-containing buffer is used for diluted sample;
(4) cleaning solution: phosphate-containing buffer need to be used with 10 times of purified water dilutions, board-washing.
The production technology of kit mainly has the following steps:
1. preparing microballon saves liquid, microballon saves the NaCl reagent that liquid main component includes: i.e. 8.0g/L, 2.9g/L's
Na2HPO412H2O reagent, the KCl reagent of 2.4g/L, the KH2PO4 reagent of 2.4g/L, the Tris reagent of 0.5g/L, 0.5mL/
The Tween20 reagent of L, the Sodium Azide reagent of 0.5g/L.
2. the activation and coating of microballoon take 1mL particular number microballon that 1.5mL centrifuge tube is added, 5-50uL EDC(1- second is added
Base-(3- dimethylaminopropyl) phosphinylidyne diimmonium salt hydrochlorate) and 5-50uL SuLfo-NHS(N- hydroxy succinyl Asia
Amine), 10-100ug specific antigen is added, is vortexed and mixes 30 seconds, ultrasound mixes 30 seconds, and 2-8 DEG C shakes up overnight.
When producing detection kit, needs to place the shaking table of 4 kinds of antigen-antibody bottles simultaneously, be coated with different numbers respectively
Microballoon, steps are as follows:
1) wash: use filtering and washing, it is washed after microballon be transferred to microballon save liquid;
2) verification quality Quality Control: is come by using Quality Control disk;
3) a variety of microballons that have been coated with are mixed, saves liquid with a small amount of microballon and wash lower bottle wall residual microballon, and mix, finally with micro-
Pearl saves liquid constant volume, dispenses after the assay was approved.
3. fluorescent marker: the sheep Anti-Human IgM(specificity γ chain of phycoerythrin label), 1 μ g/mL of initial concentration, use is micro-
Pearl saves liquid and is diluted to working concentration, and working concentration is 0.6 μ g/L.
4. concentrated cleaning solution: microballon saves 10 times of concentration versions of formula of liquid, and ingredient and microballon save liquid in concentrated cleaning solution
Ingredient it is consistent, and each constituent concentration of concentrated cleaning solution is that microballon saves 10 times of each constituent concentration of liquid.
Specific antigen includes calibration object 1, calibration object 2, calibration object 3, reference microspheres and NSC microballoon reference substance, and 2- is added in calibration object 1
The people IgM of 6-10ug/mL is added in the people IgM of 5ug/mL, calibration object 2, and the people IgM of 12-18ug/mL is added in calibration object 3, and reference is micro-
The anti-human IgM of 8-15ug/mL is added in ball, and NSC microballoon is added without any antigen as control.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, without departing from the spirit and scope of the present invention, this hair
Bright to will also have various changes and improvements, these changes and improvements all fall within the protetion scope of the claimed invention.The present invention claims
Protection scope is defined by the appending claims and its equivalent thereof.
Claims (3)
1. a kind of detection kit of the antibody IgMs such as cytomegalovirus, it is characterised in that: detection kit includes that compounded microbeads are outstanding
Supernatant liquid, fluorescence display agent, Sample dilution and cleaning solution,
Compounded microbeads suspension: including cognizable polystyrene microbeads in suspension, and polystyrene microbeads are coated with respectively
Following antigen: toxoplasma antigen, rubella antigens, big and small extracellular antigen, -1 antigen of herpes simplex virus and herpes simplex virus-2 are anti-
It is former;
Fluorescence display agent: the sheep Anti-Human IgM(specificity γ chain marked using the phycoerythrin that initial concentration is 1.0 ug/mL),
Dilution calibration is working solution concentration 0.6ug/mL, 2-8 DEG C of storage;
Sample dilution: phosphate-containing buffer is used for diluted sample;
Cleaning solution: phosphate-containing buffer need to be used with 10 times of purified water dilutions, board-washing.
2. the detection kit of the antibody IgMs such as a kind of cytomegalovirus according to claim 1, it is characterised in that: kit
Production technology mainly have the following steps:
It prepares microballon and saves liquid, microballon saves the NaCl reagent that liquid main component includes: i.e. 8.0g/L, 2.9g/L's
Na2HPO412H2O reagent, the KCl reagent of 2.4g/L, the KH2PO4 reagent of 2.4g/L, the Tris reagent of 0.5g/L, 0.5mL/
The Tween20 reagent of L, the Sodium Azide reagent of 0.5g/L;
The activation and coating of microballoon take 1mL particular number microballon that 1.5mL centrifuge tube is added, and 5-50uL EDC(1- ethyl-is added
(3- dimethylaminopropyl) phosphinylidyne diimmonium salt hydrochlorate) and 5-50uL SuLfo-NHS(N- hydroxy thiosuccinimide),
10-100ug specific antigen is added, is vortexed and mixes 30 seconds, ultrasound mixes 30 seconds, and 2-8 DEG C shakes up overnight;
Fluorescent marker: the sheep Anti-Human IgM(specificity γ chain of phycoerythrin label), 1 μ g/mL of initial concentration is saved with microballon
Liquid is diluted to working concentration, and working concentration is 0.6 μ g/L;
Concentrated cleaning solution: ingredient is consistent with the microballon preservation ingredient of liquid in concentrated cleaning solution, and each constituent concentration of concentrated cleaning solution
10 times for saving each constituent concentration of liquid for microballon.
3. the detection kit of the antibody IgMs such as a kind of cytomegalovirus according to claim 2, it is characterised in that: specific anti-
Original includes calibration object 1, calibration object 2, calibration object 3, reference microspheres and NSC microballoon reference substance, and the people of 2-5ug/mL is added in calibration object 1
The people IgM of 6-10ug/mL is added in IgM, calibration object 2, and the people IgM of 12-18ug/mL is added in calibration object 3, and 8- is added in reference microspheres
The anti-human IgM of 15ug/mL, NSC microballoon are added without any antigen as control.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810883445.7A CN109001468A (en) | 2018-08-06 | 2018-08-06 | A kind of detection kit of CMV antibody IgM |
CN202310698886.0A CN116500279A (en) | 2018-08-06 | 2018-08-06 | Detection kit for cytomegalovirus antibody IgM and application |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810883445.7A CN109001468A (en) | 2018-08-06 | 2018-08-06 | A kind of detection kit of CMV antibody IgM |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN202310698886.0A Division CN116500279A (en) | 2018-08-06 | 2018-08-06 | Detection kit for cytomegalovirus antibody IgM and application |
Publications (1)
Publication Number | Publication Date |
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CN109001468A true CN109001468A (en) | 2018-12-14 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN201810883445.7A Pending CN109001468A (en) | 2018-08-06 | 2018-08-06 | A kind of detection kit of CMV antibody IgM |
CN202310698886.0A Pending CN116500279A (en) | 2018-08-06 | 2018-08-06 | Detection kit for cytomegalovirus antibody IgM and application |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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CN202310698886.0A Pending CN116500279A (en) | 2018-08-06 | 2018-08-06 | Detection kit for cytomegalovirus antibody IgM and application |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN114113626A (en) * | 2021-10-25 | 2022-03-01 | 江苏纳迪芯生命科技研究院有限公司 | Cytokine detection kit based on magnetic particle luminescence method |
CN114113627A (en) * | 2021-10-25 | 2022-03-01 | 江苏纳迪芯生命科技研究院有限公司 | Alzheimer's disease detection kit based on magnetic particle luminescence method |
CN114113590A (en) * | 2021-10-25 | 2022-03-01 | 江苏纳迪芯生命科技研究院有限公司 | Mycoplasma pneumoniae and chlamydia antibody detection kit based on magnetic particle luminescence method |
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CN114113627A (en) * | 2021-10-25 | 2022-03-01 | 江苏纳迪芯生命科技研究院有限公司 | Alzheimer's disease detection kit based on magnetic particle luminescence method |
CN114113590A (en) * | 2021-10-25 | 2022-03-01 | 江苏纳迪芯生命科技研究院有限公司 | Mycoplasma pneumoniae and chlamydia antibody detection kit based on magnetic particle luminescence method |
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Address after: 213100 9, Yang Road, West Taihu science and technology industry, Changzhou, Jiangsu Applicant after: ZHOUSI LIFE TECHNOLOGY (CHANGZHOU) Co.,Ltd. Address before: 213100 9, Yang Road, West Taihu science and technology industry, Changzhou, Jiangsu Applicant before: YIDIZHUN BIO-TECH (CHANGZHOU) Co.,Ltd. |
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Application publication date: 20181214 |