CN108992713A - A kind of corrosion-resistant stoma leakproof cream and preparation method thereof - Google Patents

A kind of corrosion-resistant stoma leakproof cream and preparation method thereof Download PDF

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Publication number
CN108992713A
CN108992713A CN201811036918.6A CN201811036918A CN108992713A CN 108992713 A CN108992713 A CN 108992713A CN 201811036918 A CN201811036918 A CN 201811036918A CN 108992713 A CN108992713 A CN 108992713A
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CN
China
Prior art keywords
parts
stoma
corrosion
glycerol
resistant
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811036918.6A
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Chinese (zh)
Inventor
张雨成
聂正稳
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Wuhan Steadlive Medical Apparatus & Healthy Nursing Co Ltd
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Wuhan Steadlive Medical Apparatus & Healthy Nursing Co Ltd
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Priority to CN201811036918.6A priority Critical patent/CN108992713A/en
Publication of CN108992713A publication Critical patent/CN108992713A/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A61L28/0007—Materials for colostomy devices containing macromolecular materials
    • A61L28/0011—Materials for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A61L28/0003—Materials for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A61L28/0007—Materials for colostomy devices containing macromolecular materials
    • A61L28/0019—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A61L28/003—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A61L28/0034—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

Abstract

The invention proposes a kind of corrosion-resistant stoma leakproof cream and preparation method thereof, in parts by weight, including following component: liquid polyisoprene rubber: 40-60 parts, Karaya Gum: 10-35 parts, inorganic clay: 2-6 parts, glycerol: 8-20 parts, 1,2- propylene glycol: 0.5-2 parts, mineral oil: 0.5-4 parts, Sodium Polyacrylate: 2-10 parts, aluminium hydroxide: 0.1-1 parts, citric acid: 0.2-1 parts.Leakproof cream appearance of the present invention is no different with common leakproof cream, in use once contact with body fluid, can occur slowly to solidify, and complete appearance is kept not to be disintegrated, can be with expanded service life while effect of playing stably in guaranteeing use process.

Description

A kind of corrosion-resistant stoma leakproof cream and preparation method thereof
Technical field
The present invention relates to a kind of corrosion-resistant stoma leakproof cream and preparation method thereof.
Background technique
Currently, China possesses about 1,000,000 colostomy patients, stoma, which refers to, is moved enteron aisle or urethra one end by surgical operation The opening formed to body surface, is derived from digestive system or disease in the urological system, needs to separate urogaster road by operation. Colostomy patient is drained by stoma, but since making-port is without sphincter, colostomy patient is without the identically controlled row of image of Buddha normal person Just, it needs to wear ostomy bag in making-port, for temporarily collecting secretion and excreta.The stoma skin surface of some patients The irregular shapes such as fold or recess are presented, when directly sticking ostomy bag, the gap among skin and film will lead to excretion The leakage of liquid seriously affects the normal life of colostomy patient；In addition, the normal skin of stoma be chronically exposed to intestinal juice, In urine or gastric juice, red swelling of the skin inflammation will lead to, aggravate the pain of colostomy patient.
Leakproof cream is a enterostomal nursing accessory product, can be applied to irregular skin surface be used to fill and lead up fold and Recess, to achieve the effect that sealing and anti-leakage and protection normal skin.It on the market include at present alcohol and two kinds alcohol-free The leakproof cream of type, wherein there is alcohol leakproof cream to contain ethyl alcohol or isopropanol, during with skin contact, organic solvent meeting It causes stimulation to generate pain and sense of discomfort the skin, mucous membrane, the surface of a wound of some colostomy patients, skin is resulted even in when serious Skin inflammation；It is exposed among air in addition, there is alcohol leakproof cream once squeezing out, solvent can volatilize rapidly, and lotion is hardened therewith, nothing Method smearing is sprawled, therefore needs to operate rapidly when in use, increases difficulty to the daily nursing of patient.During use, leakproof Cream contacts with excrement for a long time, and especially at night, the immersion of intestinal juice or urine is final to lose so that disintegration is gradually swollen in leakproof cream The effect of going protection against leakage.
Either interim colostomy patient or permanent colostomy patient, leakproof cream are all a products for needing to be used for a long time, Stoma leakproof cream at present on the market is expensive, and lacks lasting stability.
Summary of the invention
In view of the deficiencies of the prior art, the present invention proposes a kind of corrosion-resistant stoma leakproof cream and preparation method thereof, can be to suffer from Person provides good enterostomal nursing, and leakproof cream appearance of the present invention is no different with common leakproof cream, in use once and body fluid Contact, can occur slowly to solidify, keep complete appearance be not disintegrated, guarantee use process in play stably effect while, It can be with expanded service life.
The technical scheme of the present invention is realized as follows:
A kind of corrosion-resistant stoma leakproof cream and preparation method thereof, in parts by weight, including following component:
Liquid polyisoprene rubber: 40-60 parts
Karaya Gum: 10-35 parts
Inorganic clay: 2-6 parts
Glycerol: 8-20 parts
1,2- propylene glycol: 0.5-2 parts
Mineral oil: 0.5-4 parts
Sodium Polyacrylate: 2-10 parts
Aluminium hydroxide: 0.1-1 parts
Citric acid: 0.2-1 parts.
Preferably, the inorganic clay is the one of which in montmorillonite, lithium diatomaceous earth and kaolin.
A kind of preparation method of corrosion-resistant stoma leakproof cream, which comprises the following steps:
Step 1, precise glycerol, Sodium Polyacrylate, aluminium hydroxide, citric acid are simultaneously uniformly mixed to obtain glycerol phase；
Load weighted liquid polyisoprene rubber, mineral oil, 1.2- propylene glycol are added in mixer, stirs for step 2 Half an hour is mixed to substantially uniformity, is added inorganic clay, stirring 1h is to being uniformly mixed；Karaya Gum is added, continues to stir 1h to equal It is even, it is eventually adding glycerol and mutually mixes.
The present invention is the beneficial effects are as follows: (1) raw material are easy to get safely, and low in cost, preparation process is simple；(2) it produces Product are free of organic solvent, non-stimulated to skin, stickiness can be kept to stablize after extrusion constant, tend to smear out use；(3) lotion is strong Degree is high, can effectively fill up skin depressions, good airproof performance；(4) lotion is preferable for the corrosion resistance of excreta, meets water and hands over Connection solidifies and keeps appearance stablity for a long time, can effectively stop excreta to contact with stoma normal skin, reduces skin because invading Inflammation caused by losing.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with the embodiment of the present invention, it is clear that retouched The embodiment stated is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, originally Field those of ordinary skill every other embodiment obtained without making creative work, belongs to the present invention The range of protection.
Embodiment 1:
Each substance is weighed according to following weight proportion:
Liquid polyisoprene rubber: 40g
Karaya Gum: 35g
Inorganic clay: 2g
Glycerol: 20g
1,2- propylene glycol: 0.5g
Mineral oil: 4g
Sodium Polyacrylate: 2g
Aluminium hydroxide: 1g
Citric acid: 0.2g
Precise glycerol, Sodium Polyacrylate, aluminium hydroxide, citric acid are simultaneously uniformly mixed to obtain glycerol phase；In mixer Load weighted liquid polyisoprene rubber, mineral oil, 1.2- propylene glycol is added, nothing is added in stirring half an hour to substantially uniformity Machine clay, stirring 1h to be uniformly mixed；Karaya Gum is added, continues to stir 1h to uniform, is eventually adding glycerol and mutually mixes.
Embodiment 2:
Each substance is weighed according to following weight proportion:
Liquid polyisoprene rubber: 60g
Karaya Gum: 10g
Inorganic clay: 6g
Glycerol: 8g
1,2- propylene glycol: 2g
Mineral oil: 0.5g
Sodium Polyacrylate: 10g
Aluminium hydroxide: 0.1g
Citric acid: 1g
Precise glycerol, Sodium Polyacrylate, aluminium hydroxide, citric acid are simultaneously uniformly mixed to obtain glycerol phase；In mixer Load weighted liquid polyisoprene rubber, mineral oil, 1.2- propylene glycol is added, nothing is added in stirring half an hour to substantially uniformity Machine clay, stirring 1h to be uniformly mixed；Karaya Gum is added, continues to stir 1h to uniform, is eventually adding glycerol and mutually mixes.
Embodiment 3:
Each substance is weighed according to following weight proportion:
Liquid polyisoprene rubber: 47g
Karaya Gum: 20g
Inorganic clay: 5g
Glycerol: 15g
1,2- propylene glycol: 1g
Mineral oil: 2g
Sodium Polyacrylate: 9g
Aluminium hydroxide: 0.5g
Citric acid: 0.5g
Precise glycerol, Sodium Polyacrylate, aluminium hydroxide, citric acid are simultaneously uniformly mixed to obtain glycerol phase；In mixer Load weighted liquid polyisoprene rubber, mineral oil, 1.2- propylene glycol is added, nothing is added in stirring half an hour to substantially uniformity Machine clay, stirring 1h to be uniformly mixed；Karaya Gum is added, continues to stir 1h to uniform, is eventually adding glycerol and mutually mixes.
Comparative example 1:
It is same as Example 3, it is not added with Sodium Polyacrylate in formula.
Comparative example 2
It is same as Example 3, it is not added with aluminium hydroxide in formula.
Comparative example 3
It is same as Example 3, it is not added with inorganic clay in formula.
Material property detection:
The finally obtained lotion product of above-described embodiment 1-3 and comparative example 1-3 is detected respectively:
First lotion is smeared uniformly in glass culture dish, distilled water is added, stands observation；It is applied again on metal plate surface A certain amount of lotion is smeared, ostomy bag is pasted on lotion, and pours into a certain amount of simulated intestinal fluid in bag, is completely soaked simulated intestinal fluid Lotion stands observation；After a period of time, the state change difference of lotion is compared.
Testing result is as follows:
Embodiment 1-3 sample is easy to apply, is cured after contacting with water, and corrosion resistance is strong in simulated intestinal fluid, tool There is good comprehensive performance.Comparative example 1-2 sample is easy to apply, and swelling ratio is higher；And 3 sample of comparative example is easy to apply, Swelling ratio is low, but corrosion resistance is poor, slowly can be disintegrated and disperse under simulated intestinal fluid immersion.
The reason of its generation main distinction, is analyzed:
The present invention it is creative on the basis of existing technology be added to catablasm base material (Sodium Polyacrylate gel solidification body System), Sodium Polyacrylate is the polyacrylic acid that part is neutralized, it is the straight copolymer that acrylic acid and acrylic acid are received, in addition to tool Outside adhesive feature, also have many characteristics, such as safety, thickening property.By introducing polyacrylic acid in existing leakproof lotion system Sodium and aluminium hydroxide so that leakproof cream in actual use can slowly curing molding, wherein aluminium ion can be with polymer bone Ionic reaction occurs for the carboxyl functional group in frame, and subsequent aluminium ion further acts on polymer and ultimately forms three-dimensional network knot The gel of structure, so that leakproof cream obtains certain intensity and maintains complete shape.
Simultaneously using polymer rubber as substrate, adhesive Karaya Gum and reinforcing agent inorganic clay are successively introduced, object is passed through Reason is blended and obtains the leakproof cream.Existing leakproof cream product is easy to be swollen and then be disintegrated under body fluid immersion, and of the invention In, by introducing inorganic clay, under the premise of maintaining original moulding ability, so that compound body internal structure is more densely cross-linked, With extremely strong anti-corrosion effect, dimensional stability can be kept for a long time under body fluid erosion, when extending use while guaranteeing effect Between.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (3)

1. a kind of corrosion-resistant stoma leakproof cream, which is characterized in that in parts by weight, including following component:
Liquid polyisoprene rubber: 40-60 parts
Karaya Gum: 10-35 parts
Inorganic clay: 2-6 parts
Glycerol: 8-20 parts
1,2- propylene glycol: 0.5-2 parts
Mineral oil: 0.5-4 parts
Sodium Polyacrylate: 2-10 parts
Aluminium hydroxide: 0.1-1 parts
Citric acid: 0.2-1 parts.
2. a kind of corrosion-resistant stoma leakproof cream as described in claim 1, which is characterized in that the inorganic clay be montmorillonite, One of which in lithium diatomaceous earth and kaolin.
3. such as a kind of described in any item preparation methods of corrosion-resistant stoma leakproof cream of claim 1-2, which is characterized in that including Following steps:
Step 1, precise glycerol, Sodium Polyacrylate, aluminium hydroxide, citric acid are simultaneously uniformly mixed to obtain glycerol phase；
Load weighted liquid polyisoprene rubber, mineral oil, 1.2- propylene glycol, stirring half is added in step 2 in mixer Hour to substantially uniformity, it is added inorganic clay, stirring 1h is to being uniformly mixed；Karaya Gum is added, continues to stir 1h to uniform, most Glycerol is added afterwards mutually to mix.
CN201811036918.6A 2018-09-06 2018-09-06 A kind of corrosion-resistant stoma leakproof cream and preparation method thereof Pending CN108992713A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811036918.6A CN108992713A (en) 2018-09-06 2018-09-06 A kind of corrosion-resistant stoma leakproof cream and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811036918.6A CN108992713A (en) 2018-09-06 2018-09-06 A kind of corrosion-resistant stoma leakproof cream and preparation method thereof

Publications (1)

Publication Number Publication Date
CN108992713A true CN108992713A (en) 2018-12-14

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Country Status (1)

Country Link
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244461A (en) * 2021-04-27 2021-08-13 振德医疗用品股份有限公司 Corrosion-resistant stoma leakage-proof paste for realizing strength self-regulation and control and preparation method thereof

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0880973A2 (en) * 1997-05-30 1998-12-02 Bristol-Myers Squibb Company Adhesive composition or structure
CN1268892A (en) * 1997-08-29 2000-10-04 科洛普拉斯特公司 Pressure sensitive adhesive composition
US20060141016A1 (en) * 2004-12-27 2006-06-29 Bristol-Myers Squibb Company Enzyme inhibiting adhesives
CN1950336A (en) * 2004-07-28 2007-04-18 可泰克斯有限合伙公司 Polymers produced by using sulphur compounds in the form of transfer agents for controlled radical polymerisation of acrylic acid and the use thereof
CN101045041A (en) * 2007-04-29 2007-10-03 武汉兵兵药业有限公司 Cataplasma containing ibuprofen its preparing method and application
CN101337087A (en) * 2007-06-27 2009-01-07 Tyco医疗健康集团 Foam control for synthetic adhesive/sealant
CN101909667A (en) * 2008-01-10 2010-12-08 爱乐康株式会社 Pressure-sensitive adhesive agent for skin, pressure-sensitive adhesive sheet for skin and face plate of ostomy appliance
CN101947322A (en) * 2010-09-03 2011-01-19 南方医科大学 Gel patch matrix and preparation method and application thereof
CN102397242A (en) * 2011-09-02 2012-04-04 河南康倍得药业有限公司北京技术开发中心 Hydrogel containing coenzyme Q10, and cataplasm prepared by hydrogel
CN106310353A (en) * 2015-07-03 2017-01-11 江苏诺瓦立医疗用品有限公司 Hydrocolloid adhesive, related application and hydrocolloid dressing
CN107206118A (en) * 2015-01-28 2017-09-26 霍利斯特股份有限公司 For the stoma edge device for moistening the adhesive of tissue and being made using the adhesive
CN108096628A (en) * 2018-01-04 2018-06-01 武汉市思泰利医疗器械发展有限公司 A kind of special paste of stoma and preparation method thereof

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0880973A2 (en) * 1997-05-30 1998-12-02 Bristol-Myers Squibb Company Adhesive composition or structure
CN1268892A (en) * 1997-08-29 2000-10-04 科洛普拉斯特公司 Pressure sensitive adhesive composition
CN1950336A (en) * 2004-07-28 2007-04-18 可泰克斯有限合伙公司 Polymers produced by using sulphur compounds in the form of transfer agents for controlled radical polymerisation of acrylic acid and the use thereof
US20060141016A1 (en) * 2004-12-27 2006-06-29 Bristol-Myers Squibb Company Enzyme inhibiting adhesives
CN101045041A (en) * 2007-04-29 2007-10-03 武汉兵兵药业有限公司 Cataplasma containing ibuprofen its preparing method and application
CN101337087A (en) * 2007-06-27 2009-01-07 Tyco医疗健康集团 Foam control for synthetic adhesive/sealant
CN101909667A (en) * 2008-01-10 2010-12-08 爱乐康株式会社 Pressure-sensitive adhesive agent for skin, pressure-sensitive adhesive sheet for skin and face plate of ostomy appliance
CN101947322A (en) * 2010-09-03 2011-01-19 南方医科大学 Gel patch matrix and preparation method and application thereof
CN102397242A (en) * 2011-09-02 2012-04-04 河南康倍得药业有限公司北京技术开发中心 Hydrogel containing coenzyme Q10, and cataplasm prepared by hydrogel
CN107206118A (en) * 2015-01-28 2017-09-26 霍利斯特股份有限公司 For the stoma edge device for moistening the adhesive of tissue and being made using the adhesive
CN106310353A (en) * 2015-07-03 2017-01-11 江苏诺瓦立医疗用品有限公司 Hydrocolloid adhesive, related application and hydrocolloid dressing
CN108096628A (en) * 2018-01-04 2018-06-01 武汉市思泰利医疗器械发展有限公司 A kind of special paste of stoma and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244461A (en) * 2021-04-27 2021-08-13 振德医疗用品股份有限公司 Corrosion-resistant stoma leakage-proof paste for realizing strength self-regulation and control and preparation method thereof
WO2022227321A1 (en) 2021-04-27 2022-11-03 振德医疗用品股份有限公司 Corrosion-resistant stoma leakage-proof paste capable of achieving self-regulation of strength and preparation method therefor

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