CN108992604A - A kind of Chinese medicine composition and preparation method thereof for treating heat type acute and chronic appendicitis - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating heat type acute and chronic appendicitis Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compositions for treating heat type acute and chronic appendicitis comprising: honeysuckle, dandelion, radix scrophulariae, semen coicis, Semen Benincasae, rhizoma corydalis, radix aucklandiae, peach kernel may also include olibanum, myrrh；The invention also discloses the preparation methods of above-mentioned Chinese medicine composition.Prescription of the invention is particular about the mutual compatibility of monarch, and reasonable recipe can effectively improve the synergistic effect between drug, the promoting flow of qi and blood circulation, regulating the flow of vital energy and dispeling melancholy, dredging intestines, removing toxic substances stagnation resolvation, the stasis of blood that ecphyaditis can thoroughly be dissolved is stagnant, reaches the purpose of radical cure, and without obvious liver renal toxicity.Have many advantages, such as that good effect, at low cost, cure rate is high, has no adverse reaction in terms for the treatment of heat type acute and chronic appendicitis using such Chinese medicine composition.
Description
Technical field
The present invention relates to a kind of medicinal preparation more particularly to a kind of Chinese medicine compositions for treating heat type acute and chronic appendicitis
And preparation method thereof.
Background technique
Ecphyaditis is a kind of common disease.Clinically often there are right lower abdomen pain, body temperature to increase, vomiting and neutrophil leucocyte increase
It is wait performance more.The obstruction of bacterium infection and appendiceal lumen is two principal elements of ecphyaditis morbidity.Appendix is one elongated blind
Pipe, lumen is narrow, excrement and bacterium of the easy retention from enteric cavity.Appendiceal wall is imbued with nervous device (such as muscular nerve clump), appendix
Root and the structure for having similar sphincter, thus it is stimulated when be easy to shrink keep lumen more narrow.Appendicular artery is dynamic for ieoocolon
The branched ending of arteries and veins is an end-artery, therefore because of stimulation generation contracture or when having obstruction, the ischemic for often incurring appendix is even bad
Extremely.Ecphyaditis is because bacterium infection causes, but without specific pathogen.Escherichia coli, enterococcus can be found usually in appendiceal lumen
And streptococcus etc., but must be after appendiceal mucous membrane damages, these bacteriums, which could invade, causes ecphyaditis.Appendiceal lumen can be because
Coprolite, helminth etc. cause mechanical obstruction, can also cause appendix spasm because of various stimulations, the blood circulation of appendiceal wall is caused to hinder
Hinder and cause mucosal injury, is conducive to bacterium infection and causes ecphyaditis.
This disease belongs to the scope of traditional Chinese medicine " acute appendicitis ".Acute appendicitis can be divided into acute appendicitis and small intestinal abscess, include a variety of abdominal cavities
Interior purulent inflammation, acute appendicitis generally refer to acute appendicitis.This noun of acute appendicitis has been described in "Nei Jing", Han dynasty Zhang Zhong
Scape summarizes the experience for the treatment of acute appendicitis before Han dynasty in " Synopsis Golden Chamber ", has formulated the fundamentum of diagnosis and treatment.Later Sui
Write towards Chao Yuanfang (550-630 A.D.) further indicated written by " General Treatise on the Cause and Symptoms of Diseases " and Ming Dynasty's Chen Shigong " surgery is authentic " extravasated blood stagnate, violent fortune
It is dynamic, postpartum loses the factors such as the stasis of blood, not having regular daily life can cause acute appendicitis.
This disease of western medical treatment mainly uses anti-inflammatory therapy and operative treatment.Operation was mostly used to treat the treatment of this disease in the past
There are two ways to method, treatment ecphyaditis: one, using operative treatment by appendectomy, this method curative effect is fast and can eradicate, but
Patient spend it is more, receiving to operate on pain larger, and surgical disruption abdominal cavity original physiological status, the convalescence after Miles operation
Fault that is long, occurring when especially performing the operation, causes postoperative sequelae, has great risk.Second is that Chinese and western drugs are treated, it is conventional
Western medical treatment, medical expense is high, and treatment time is long, and patient is painful and easy to recur, and side effect is larger.Current some Chinese medicines are matched
Side treatment, though obtain some positive therapeutics, it is generally existing that the ecphyaditis cause of disease cannot be eradicated, return the reason is that: at present in
Hospital's agent both for large intestine it is damp and hot accumulate product implement it is logical under expel the heat-evil, it is interim it is damp and hot be mitigated or eliminated, swelling pain then disappears therewith
It loses, it is believed that disease has been cured.But stagnation of QI-blood is not dissolved but at all, and after a period of time, the stasis of blood is stagnant and can change heat, swelling
Pain will occur again, form Chinese medicine treatment ecphyaditis common reason easy to recur.Currently, domestic carry out with traditional Chinese medicine is
The research of this disease of main treatment, but curative effect is not generally good enough, and does not occur effectively being treated for heat type acute and chronic appendicitis
Chinese medicine.
Therefore, it is urgent to provide it is a kind of can clearing heat and detoxicating, swelling and pain relieving, can be widely applied to treatment heat type acute and chronic appendicitis
Chinese medicine composition.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of clearing heat and detoxicating energy, swelling and pain relieving, can be widely applied to treatment heat
The Chinese medicine composition and preparation method thereof of type acute and chronic appendicitis.
The technical solution adopted by the present invention is that: a kind of Chinese medicine composition for treating heat type acute and chronic appendicitis, the Chinese medicine
The each component of composition is honeysuckle, dandelion, radix scrophulariae, semen coicis, Semen Benincasae, rhizoma corydalis, radix aucklandiae, peach kernel；
Further, the parts by weight of various components be honeysuckle 25-35 parts, 25-35 parts of dandelion, 25-35 parts of radix scrophulariae,
13-23 parts of semen coicis, 1-11 parts of Semen Benincasae, 1-11 parts of rhizoma corydalis, 1-11 parts of radix aucklandiae, 4-14 parts of peach kernel；
Further, the parts by weight of various components be honeysuckle 28-32 parts, 28-32 parts of dandelion, 28-32 parts of radix scrophulariae,
16-20 parts of semen coicis, 4-8 parts of Semen Benincasae, 4-8 parts of rhizoma corydalis, 4-8 parts of radix aucklandiae, 7-11 parts of peach kernel；
It further, further include olibanum, myrrh；
Further, the parts by weight of olibanum are 1-11 parts, and the parts by weight of myrrh are 1-11 parts；
Further, the parts by weight of olibanum are 4-8 parts, and the parts by weight of myrrh are 4-8 parts；
Further, the dosage form of the Chinese medicine composition are as follows: decoction, tablet, pulvis or pill；
Further, the dosage form of the Chinese medicine composition is decoction；
The invention also discloses the preparation methods of the Chinese medicine composition for the treatment of heat type acute and chronic appendicitis as described above, work as institute
When the dosage form for stating Chinese medicine composition is decoction, comprising:
It is uniformly mixed after each bulk pharmaceutical chemicals are crushed and the water that 10-30 times of bulk pharmaceutical chemicals mixture quality is added impregnates 1-2 hours
And then be cooked by slow fire 1-3 hours, after being filtered to remove the dregs of a decoction, continuing to decoct sticky to soup is product；；
When the dosage form of the Chinese medicine composition is pulvis, comprising:
It is uniformly mixed after each bulk pharmaceutical chemicals are crushed and the water that 10-30 times of bulk pharmaceutical chemicals mixture quality is added impregnates 1-2 hours
And then be cooked by slow fire 1-3 hours, after being filtered to remove the dregs of a decoction, it is product that high fire, which receives and does, crushes obtained solid,；
When the dosage form of the Chinese medicine composition is pill, comprising:
By each bulk pharmaceutical chemicals crush after be uniformly mixed and be added 10-30 times of bulk pharmaceutical chemicals mixture quality water immersion 1-2 hours,
Decoct 2-3 hour, after being filtered to remove the dregs of a decoction, high fire receive it is dry, obtained solid is crushed after with sweet general ball be product.
Honeysuckle, it is cold in nature, it is sweet in flavor, enter lung, the heart, stomach meridian, has effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind, cure mainly swollen
Completely descend disease, warm disease heating, the diseases such as heat toxin large carbuncle and tumour.It is for dizziness, thirst, sweating and boring, enteritis, bacterium
Dysentery, morbilli, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, ecphyaditis, skin infection, ulcer boils, erysipelas, the parotid gland
The illnesss such as inflammation, suppurative tonsillitis have certain curative effect.
Dandelion, nature and flavor are sweet, slight bitter, tremble with fear.Return liver, stomach meridian.There are diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogue and other effects.Control heat toxin,
Carbuncle swells, sore, internal carbuncle, red eye, swell pain, damp and hot, jaundice, the puckery pain of dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, hot eyes,
Pharyngalgia, pulmonary abscess, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctiva
Inflammation, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections etc..
Radix scrophulariae, sweet in flavor, bitter, salty, cold nature has the effect of clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass.
Rhizoma corydalis, acrid flavour, hardship are warm-natured, nontoxic.Return liver, stomach, the heart, lung, the spleen channel, invigorates blood circulation；Dissipate the stasis of blood；Qi-regulating；Analgesic.The main heart
The all pains of abdomen waist and knee；Irregular menstruation；Abdominal mass；Metrorrhagia；Postpartum anemic fainting；Lochiorrhagia；Traumatic injury.
Semen Benincasae, sweet in flavor, cool in nature, return heart, lung, spleen, kidney channel, energy moistening lung for removing phlegm, and benefit stomach Qi, " book on Chinese herbal medicine states hook member " claim it
Knot is poly- in main abdomen, ulceration purulence blood, stops up in all stomach, the most key medicine.
Semen coicis, sweet in flavor, light, cool in nature, returns spleen, stomach, lung channel, advantageous water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, removing toxic substances
The effect of dissipating bind is used for oedema, tinea pedis, difficult urination, splenasthenic diarrhea, arthritis with fixed pain caused by dampness muscular constricture, pulmonary abscess, acute appendicitis；Wart, cancerous swelling.
Radix aucklandiae, acrid flavour, hardship are warm-natured, nontoxic, returns spleen, large intestine, tri-jiao channel, there is promoting the circulation of qi, analgesic, invigorating the spleen, the effect of helping digestion,
The major functions: promoting in promoting qi circulation and relieving pain, tune；Weight after main born of the same parents coerce turgor foot, abdominal distention, spit diarrhea, dysentery；For chest gastral cavity distending pain,
Weight after rush down dysentery, dyspepsia, do not feel like eating, middle gas do not save, sudden deafness, snakebite and bugbite, toothache.
Peach kernel, bitter, sweet, mild-natured, return heart, liver, large intestine channel have promoting blood circulation, relax bowel and defecation, relieving cough and asthma function
Effect.For amenorrhea and algomenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
Olibanum, acrid flavour, hardship are warm-natured, return heart, liver, the spleen channel, have the effect of blood-activating and qi-promoting analgesic, detumescence and promoting granulation, are used for thoracic obstruction
It is pained, gastral cavity pain, dysmenorrhea menostasis, postpartum stasis, abdominal mass abdominal pain, rheumatic arthralgia, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
Myrrh, acrid flavour, hardship are mild-natured, return heart, liver, the spleen channel, have the effect of scattered stasis pain, detumescence and promoting granulation.It is usually used in thoracic obstruction
Pained, gastral cavity pain, dysmenorrhea menostasis, postpartum stasis , abdominal mass and abdominal pain, rheumatic arthralgia, traumatic injury, the illnesss such as carbuncle swells sore control
It treats.
Beneficial effects of the present invention:
1) acute appendicitis is mostly gathered by enteral, strongly fragrant and change heat, it is damp and hot it is stifling form heat toxin, therefore swollen break out and pain are acutely；
Chronic appendicitis is run, large intestine transporting disorder mostly by feeding desorder, or after food, qi and blood stagnation and cause right lower abdominal pain.Our gold
Honeysuckle flower, dandelion, the radix scrophulariae clearing heat and detoxicating, swelling and pain relieving for monarch drug in a prescription；Semen coicis, Semen Benincasae are ministerial drug heat-clearing, the carbuncle that disappears, apocenosis；Make
It is the rhizoma corydalis of adjuvant, Muxiangliqi relieve stagnation to relieve pain, peach kernel, olibanum, myrrh activating microcirculation and removing stasis medicinal, alleviating pain and detumescence (visual symptom
Weight chooses whether addition olibanum, myrrh)；All medicines combines, qi-regulating dissipate it is strongly fragrant with analgesic, the stasis of blood for thoroughly dissolving ecphyaditis is stagnant, reach
The purpose of radical cure.
2) prescription of the invention is particular about the mutual compatibility of monarch, and reasonable recipe can effectively improve the collaboration between drug
Effect, the promoting flow of qi and blood circulation, regulating the flow of vital energy and dispeling melancholy, dredging intestines, removing toxic substances stagnation resolvation, and without obvious liver renal toxicity.
Specific embodiment
Embodiment 1:
(1) a kind of Chinese medicine for treating heat type acute and chronic appendicitis gram is matched by weight by following bulk pharmaceutical chemicals:
30 grams of honeysuckle, 30 grams of dandelion, 30 grams of radix scrophulariae, 18 grams of semen coicis, 6 grams of Semen Benincasae, 6 grams of rhizoma corydalis, radix aucklandiae 6
Gram, 9 grams of peach kernel.
(2) preparation method:
It is uniformly mixed and is added after each bulk pharmaceutical chemicals are crushed after water immersion 1 hour of 20 times of bulk pharmaceutical chemicals mixture quality,
It is cooked by slow fire again 2 hours, after being filtered to remove the dregs of a decoction, continuing to decoct sticky to soup is product.
Embodiment 2:
(1) a kind of Chinese medicine for treating heat type acute and chronic appendicitis gram is matched by weight by following bulk pharmaceutical chemicals:
30 grams of honeysuckle, 30 grams of dandelion, 30 grams of radix scrophulariae, 18 grams of semen coicis, 6 grams of Semen Benincasae, 6 grams of rhizoma corydalis, radix aucklandiae 6
Gram, 9 grams of peach kernel, 6 grams of olibanum, 9 grams of peach kernel.
(2) preparation method:
It is uniformly mixed and is added after each bulk pharmaceutical chemicals are crushed after water immersion 1 hour of 20 times of bulk pharmaceutical chemicals mixture quality,
It is cooked by slow fire again 2 hours, after being filtered to remove the dregs of a decoction, continuing to decoct sticky to soup is product.
Embodiment 3:
Diagnostic criteria:
All acute appendicitis category heat type persons, right abdomen appendix area severe pain, involve lower part, the right normal buckling of leg is not stretched, abdomen
Spasmic pain is made in interior local swelling, can not hand press, and aversion to cold, body heat, vomiting.Full and rapid pulse, dry urgency of defecating, oliguria with yellow urine, three
Five at purulence or Complicating Peritonitis disease；
Chronic appendicitis symptom and Acute Phase are same, but more acute slow, and pain is not very violent, and body temperature is also not very high.
Effective cure rate of Chinese medicine of the invention counts, and criterion of therapeutical effect is as follows:
Recovery from illness: clinical symptoms all disappear, and laboratory checks normal；
Effective: clinical symptom relief, laboratory check improvement or normal；
Invalid: no significant improvement or aggravated in clinical symptoms.
The present invention, which treats, participates in heat type acute and chronic appendicitis patient 45-70 year old totally 120 of statistics, is divided into basic side and treats
Olibanum, every group for the treatment of group's (side's of adding group) of myrrh, control group 40 people is added in group (referred to as basic group) on the basis of basic side:
Basic group: one time 200ml twice a day even served five；
The side's of adding group: a 200ml twice a day even served five；
Control group: one time 15, three times per day, even served five.
| Group | It cures | Effectively | In vain | Total effective rate |
| Basic group | 19 | 19 | 3 | 95% |
| The side's of adding group | 25 | 14 | 1 | 97.5% |
| Control group | 14 | 17 | 9 | 77.5% |
Therefore basic group and add the total effective rate difference just organized little, but the cure rate group more substantially just organized is added to want
Some higher, illustrating that difference on prescription still has drug effect centainly influences, it is comprehensive for, our drug effect is relatively stable,
And apparent liver renal toxicity or other toxic side effects are not found during treatment.
Simply to illustrate that technical concepts and features of the invention, its purpose is allows in the art above-described embodiment
Those of ordinary skill cans understand the content of the present invention and implement it accordingly, and it is not intended to limit the scope of the present invention.It is all
It is changes or modifications equivalent made by the essence of content according to the present invention, should all covers in protection scope of the present invention.
Claims (10)
1. a kind of Chinese medicine composition for treating heat type acute and chronic appendicitis, which is characterized in that each component of the Chinese medicine composition
For honeysuckle, dandelion, radix scrophulariae, semen coicis, Semen Benincasae, rhizoma corydalis, radix aucklandiae, peach kernel.
2. Chinese medicine composition as described in claim 1, which is characterized in that the parts by weight of various components are honeysuckle 25-35
Part, 25-35 parts of dandelion, 25-35 parts of radix scrophulariae, 13-23 parts of semen coicis, 1-11 parts of Semen Benincasae, 1-11 parts of rhizoma corydalis, radix aucklandiae 1-11
Part, 4-14 parts of peach kernel.
3. Chinese medicine composition as claimed in claim 2, which is characterized in that the parts by weight of various components are honeysuckle 28-32
Part, 28-32 parts of dandelion, 28-32 parts of radix scrophulariae, 16-20 parts of semen coicis, 4-8 parts of Semen Benincasae, 4-8 parts of rhizoma corydalis, 4-8 parts of radix aucklandiae,
7-11 parts of peach kernel.
4. treating the Chinese medicine composition of heat type acute and chronic appendicitis as described in any one of claim 1-3, which is characterized in that also
Including olibanum, myrrh.
5. the Chinese medicine composition for the treatment of heat type acute and chronic appendicitis as claimed in claim 4, which is characterized in that the parts by weight of olibanum
Number is 1-11 parts, and the parts by weight of myrrh are 1-11 parts.
6. the Chinese medicine composition for the treatment of heat type acute and chronic appendicitis as claimed in claim 5, which is characterized in that the parts by weight of olibanum
Number is 4-8 parts, and the parts by weight of myrrh are 4-8 parts.
7. treating the Chinese medicine composition of heat type acute and chronic appendicitis as described in any one of claim 1-6, which is characterized in that institute
State the dosage form of Chinese medicine composition are as follows: decoction, tablet, pulvis or pill；Preferably decoction.
8. a kind of preparation side for the Chinese medicine composition for treating heat type acute and chronic appendicitis as described in any one of claim 1-7
Method, it is characterised in that: when the dosage form of the Chinese medicine composition is decoction, comprising:
It is uniformly mixed and is added after each bulk pharmaceutical chemicals are crushed after water immersion 1-2 hours of 10-30 times of bulk pharmaceutical chemicals mixture quality,
It is cooked by slow fire again 1-3 hours, after being filtered to remove the dregs of a decoction, continuing to decoct sticky to soup is product.
9. a kind of preparation side for the Chinese medicine composition for treating heat type acute and chronic appendicitis as described in any one of claim 1-7
Method, it is characterised in that: when the dosage form of the Chinese medicine composition is pulvis, comprising:
It is uniformly mixed and is added after each bulk pharmaceutical chemicals are crushed after water immersion 1-2 hours of 10-30 times of bulk pharmaceutical chemicals mixture quality,
It is cooked by slow fire again 1-3 hours, after being filtered to remove the dregs of a decoction, it is product that high fire, which receives and does, crushes obtained solid,.
10. a kind of preparation side for the Chinese medicine composition for treating heat type acute and chronic appendicitis as described in any one of claim 1-7
Method, it is characterised in that: when the dosage form of the Chinese medicine composition is pill, comprising:
It is uniformly mixed after each bulk pharmaceutical chemicals are crushed and the water that 10-30 times of bulk pharmaceutical chemicals mixture quality is added impregnates 1-2 hours, decocts
2-3 hours, after being filtered to remove the dregs of a decoction, high fire receive it is dry, obtained solid is crushed after with the general ball of honey be product.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007056432A2 (en) * | 2005-11-07 | 2007-05-18 | Perque, Llc. | Compositions for regulating intestinal disorders and methods of use thereof |
| CN101152495A (en) * | 2007-09-17 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating chronic appendicitis |
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2018
- 2018-10-31 CN CN201811282825.1A patent/CN108992604A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007056432A2 (en) * | 2005-11-07 | 2007-05-18 | Perque, Llc. | Compositions for regulating intestinal disorders and methods of use thereof |
| CN101152495A (en) * | 2007-09-17 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating chronic appendicitis |
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| 刘迪加: "张善才先生自拟肠痈汤治疗慢性阑尾炎99例", 《河南中医》 * |
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Effective date of registration: 20190808 Address after: 266000 Shandong city of Qingdao province Jiangsu City Road 16, the Affiliated Hospital of Qiingdao University Applicant after: THE AFFILIATED HOSPITAL OF QINGDAO University Address before: 266000 Department of Gastroenterology, Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Southern District of Qingdao City, Shandong Province Applicant before: Liu Hua |
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Application publication date: 20181214 |