CN108986901B - IVF quality control method, terminal equipment and system - Google Patents
IVF quality control method, terminal equipment and system Download PDFInfo
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Abstract
The invention discloses an IVF quality control method, terminal equipment and a system. The IVF quality control method comprises the following steps: displaying an information display and input interface associated with the operation object on the terminal equipment according to a preset flow; displaying an operation prompt associated with the operation object on the information display and input interface; acquiring and recording current data input according to the operation prompt; displaying a feedback prompt according to the current data and the historical data and according to a preset logic or a preset algorithm; and acquiring and recording the adjustment data input according to the feedback prompt. The scheme provided by the invention can guide the operation of operators through real-time data interaction, and better control the operation quality of the embryo laboratory.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to an IVF quality control method, terminal equipment and system.
Background
Assisted reproduction is a short term for ART (Assisted reproduction Technology) Technology, and refers to a Technology for making a sterile couple pregnant by medical assistance, including Artificial Insemination (AI) and In Vitro Fertilization-Embryo Transfer (IVF-ET) and derivatives thereof. In the IVF (also called tube transfer technique, hereinafter referred to as IVF), various assisted reproductive specimens such as sperm and ovum in vitro fertilization operations, embryo transfer operations, and freezing and reviving of embryos can be checked by a special IVF system check mode.
At present, although a special IVF checking system is arranged in an IVF embryo laboratory, when an operator operates a patient sample in the laboratory, various related information of the patient sample and the experiment operation still needs to be manually recorded and transcribed into a medical record management system of a reproduction center, the operation efficiency of the process is low, real-time interaction with related data in the medical record system cannot be carried out in real time, and the quality control (quality control for short) function is weak.
Disclosure of Invention
In view of this, the present invention provides an IVF quality control method, a terminal device and a system, which can guide an operator to operate through real-time data interaction, so as to better perform operation quality control in an embryo laboratory.
According to an aspect of the present invention, there is provided an IVF quality control method, comprising:
displaying an information display and input interface associated with the operation object on the terminal equipment according to a preset flow;
displaying an operation prompt associated with the operation object on the information display and input interface;
acquiring and recording current data input according to the operation prompt;
displaying a feedback prompt according to the current data and the historical data and according to a preset logic or a preset algorithm;
and acquiring and recording the adjustment data input according to the feedback prompt.
Preferably, before the terminal device displays the information display and input interface associated with the operation object according to the preset flow, the method further includes:
and positioning the current operation object through the terminal equipment.
Preferably, the positioning the current operation object through the terminal device includes:
and positioning the current operation object of the terminal equipment in a manual selection or chip automatic positioning mode.
Preferably, the operation object comprises a patient for assisted reproduction;
the information display and input interface associated with the operation object comprises: a functional interface to semen handling, egg aspiration, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or embryo transfer associated with the assisted reproductive patient.
Preferably, the input comprises a voice input or a manual input.
Preferably, the terminal device is a tablet computer in the IVF verification system.
Preferably, the displaying a feedback prompt according to the current data and the historical data and according to a preset logic or a preset algorithm includes:
performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis according to the current data and the historical data and according to a preset logic or a preset algorithm;
and displaying the analysis result as a feedback prompt.
Preferably, the performing the quality control analysis comprises: analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator; or the like, or, alternatively,
the performing culture solution quality control analysis comprises: performing comparative analysis according to the culture solution parameter records and the culture effect records of different culture solutions to determine a culture solution with a good culture effect; or the like, or, alternatively,
the performing the time quality control analysis comprises: analyzing the time distribution conditions of different operations according to the recorded time points of the start and the end of each operation and the operation time limit; or the like, or, alternatively,
the performing the workload quality control analysis comprises: analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier; or the like, or, alternatively,
the performing of the equipment quality control analysis comprises: analyzing whether the equipment meets the quality control requirement of the equipment or not according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation; or the like, or a combination thereof,
the performing consumable quality control analysis comprises: and analyzing whether the consumable use meets the consumable quality control requirement or not according to the consumable quantity, the consumable name and the consumable consumption standard.
According to another aspect of the present invention, there is provided an IVF terminal device comprising:
the display module is used for displaying an information display and input interface associated with the operation object on the terminal equipment according to a preset flow;
the first prompt module is used for displaying an operation prompt related to the operation object on the information display and input interface displayed by the display module;
the first acquisition module is used for acquiring and recording current data input according to the operation prompt of the first prompt module;
the second prompting module is used for displaying a feedback prompt according to the current data and the historical data acquired by the first acquiring module and a preset logic or a preset algorithm;
and the second acquisition module is used for acquiring and recording the adjustment data input according to the feedback prompt of the second prompt module.
Preferably, the apparatus further comprises:
and the positioning module is used for positioning the current operation object.
Preferably, the information display and input interface associated with the operation object displayed by the display module includes: functional interfaces for semen handling, egg retrieval, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or embryo transfer associated with patients assisting reproduction.
Preferably, the second prompting module includes:
the analysis submodule is used for performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis according to the current data and the historical data and according to a preset logic or a preset algorithm;
and the feedback submodule is used for displaying the analysis result of the analysis submodule as a feedback prompt.
According to another aspect of the present invention, there is provided an IVF quality control system comprising:
the terminal equipment is used for displaying an information display and input interface associated with the operation object according to a preset flow; displaying an operation prompt associated with the operation object on the information display and input interface; acquiring current data input according to the operation prompt, recording and sending the current data to a server, receiving a feedback prompt generated by analyzing the current data and the historical data sent by the server according to the terminal equipment, and displaying the feedback prompt on an information display and input interface;
and the server is used for receiving the current data sent by the terminal equipment, analyzing according to the current data and the historical data to generate a feedback prompt, and sending the feedback prompt to the terminal equipment.
It can be found that, after the terminal device displays the information display and input interface associated with the operation object according to the preset flow, the operation prompt associated with the operation object is displayed on the information display and input interface; after the current data input according to the operation prompt is obtained and recorded, the feedback prompt can be displayed according to the current data and the historical data and according to a preset logic or a preset algorithm. Therefore, the scheme of the invention can reduce information input errors in laboratory operation, can also guide the specific operation of the operator through real-time data interaction, guides the operator to do different responses and operations in a standardized way according to preset logic and interactive data, reduces unnecessary operations or error operations of the operator, records the specific operation of the operator and gives a prompt to make the experimental operation more standardized and accurate, thereby realizing computer-aided decision-making to a certain extent, finely managing the details of the operation, the condition of the sample and the like of a laboratory sample which cannot be managed in place in the past, and realizing the more extensive quality control of an embryo laboratory.
Drawings
The above and other objects, features and advantages of the present disclosure will become more apparent by describing in greater detail exemplary embodiments thereof with reference to the attached drawings, in which like reference numerals generally represent like parts throughout.
FIG. 1 is a schematic flow diagram of an IVF quality control method according to an embodiment of the invention;
FIG. 2 is another schematic flow diagram of a method of IVF quality control according to an embodiment of the present invention;
FIG. 3 is a schematic illustration of a partial interface region of an information display and input interface for semen processing according to one embodiment of the present invention;
fig. 4 is a schematic block diagram of an IVF terminal device according to an embodiment of the present invention;
fig. 5 is another schematic block diagram of an IVF terminal device according to an embodiment of the present invention;
fig. 6 is a schematic block diagram of an IVF quality control system according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to specific embodiments and the accompanying drawings.
While the preferred embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
The invention provides an IVF quality control method which can guide operators to operate through real-time data interaction and better control the operation quality of an embryo laboratory.
The technical solutions of the embodiments of the present invention are described in detail below with reference to the accompanying drawings.
Fig. 1 is a schematic flow diagram of an IVF quality control method according to an embodiment of the invention. The method can be applied to IVF terminal equipment.
Referring to fig. 1, the method of this embodiment comprises:
in step 101, an information display and input interface associated with an operation object is displayed according to a preset flow at a terminal device.
Wherein the operation object may be a patient assisting reproduction, and the information display and input interface associated with the operation object may include: functional interfaces for semen handling, egg aspiration, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or embryo transfer, etc., associated with the assisted reproductive patient.
In step 102, an operation prompt associated with the operation object is displayed on the information display and input interface.
For example, clicking on a patient's embryo culture displays all relevant information and prompts associated with the patient's embryo culture on the embryo culture interface.
In step 103, the current data input according to the operation prompt is acquired and recorded.
Wherein the input may comprise a voice input or a manual input, etc.
In step 104, a feedback prompt is displayed according to the current data and the historical data and according to a preset logic or a preset algorithm.
Wherein, this step can include:
performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable quality control analysis according to the current data and the historical data and according to a preset logic or a preset algorithm;
and displaying the analysis result as a feedback prompt.
Wherein:
the personnel quality control analysis can be used for analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator;
performing quality control analysis on the culture solution, namely performing comparative analysis according to the parameter records and the culture effect records of the culture solution of different culture solutions to determine the culture solution with good culture effect;
time quality control analysis, which can be used for analyzing the time distribution condition of different operations according to the recorded time points of the start and the end of each operation and the operation time limit;
the workload quality control analysis can be used for analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier;
analyzing the equipment quality control, wherein whether the equipment meets the equipment quality control requirement or not can be analyzed according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation;
the quality control analysis of the consumable materials can be whether the analysis consumable materials meet the quality control requirements of the consumable materials according to the quantity of the consumable materials, the name of the consumable materials and the consumption standard of the consumable materials.
It should be noted that, the above is exemplified but not limited to displaying the feedback prompt on the information display and input interface by the terminal device according to the acquired current data and historical data and according to the preset logic or preset algorithm, and the feedback prompt may be displayed on the information display and input interface after the terminal device receives the feedback prompt generated by analyzing the current data and the historical data sent by the server according to the terminal device.
In step 105, the adjustment data input according to the feedback prompt is obtained and recorded.
Wherein the input may comprise a voice input or a manual input, etc.
Before the terminal device displays the information display and input interface associated with the operation object according to the preset flow, the method may further include: the current operation object is positioned through the terminal equipment, wherein the current operation object can be positioned through the terminal equipment in a mode of manual selection or automatic chip positioning.
As can be seen from this embodiment, in the scheme of the present invention, after the terminal device displays the information display and input interface associated with the operation object according to the preset flow, the operation prompt associated with the operation object is displayed on the information display and input interface; after the current data input according to the operation prompt is obtained and recorded, the feedback prompt can be displayed according to the current data and the historical data and according to a preset logic or a preset algorithm. Therefore, the scheme of the invention can reduce information input errors in laboratory operation, can also guide the specific operation of the operator through real-time data interaction, guides the operator to do different responses and operations in a standardized way according to preset logic and interactive data, reduces unnecessary operations or wrong operations of the operator, records the specific operation of the operator and gives a prompt to make the experimental operation more standardized and accurate, thereby realizing computer-aided decision making to a certain extent, finely managing the details of laboratory sample operation, sample conditions and the like which cannot be managed in place in the past, and realizing the wider quality control of the embryo laboratory.
Fig. 2 is another schematic flow diagram of an IVF quality control method according to an embodiment of the invention. The method can be applied to IVF terminal equipment.
Referring to fig. 2, the method of this embodiment includes:
in step 201, the current patient information is located on the IVF terminal.
The IVF terminal equipment can be a tablet computer in the IVF checking system, or other terminal equipment and the like. That is, the tablet computer of the conventional IVF checking system can be utilized, so that the entry is more convenient than the case that one computer is arranged beside the tablet computer, and because some operating positions in a laboratory are smaller and computers for entry cannot be added beside the laboratory, the tablet computer of the conventional IVF checking system can be directly utilized more conveniently.
This step is exemplified by a patient who is assisted in reproduction by the positioned operation object.
For example, the IVF terminal can locate the current patient information on the IVF terminal by manual selection or automatic chip location.
The automatic chip positioning refers to positioning by combining with an original IVF checking system. The IVF checking system is characterized in that each vessel is provided with an RFID chip label for identifying the identity of a patient, when the vessel is placed in an operation area, the identity information of the chip label attached to the vessel is identified and acquired by a sensor on the IVF checking system and is transmitted to the IVF terminal equipment, and therefore the current patient can be automatically positioned on an information display and input interface.
In step 202, an information display and input interface associated with the current patient is displayed according to a preset flow.
The information display and input interface associated with the current patient includes: semen handling, egg retrieval, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or functional interface for embryo transfer, etc.
For example, this step may display a current patient semen handling function interface, an embryo culture function interface, or an embryo transfer function interface, etc.
The preset flow is generally preset in the system according to the checking and quality control requirements. For example, after obtaining semen from a male patient, the sequence of sperm manipulation in an embryo laboratory is typically "optimized" for sperm (e.g., gradient centrifugation to separate sperm from other cells and debris), followed by "sperm count" and "sperm conditioning. Under the preset flow, the terminal device can display a corresponding semen processing interface capable of inputting relevant semen information, and can prompt an operator to input relevant information of semen optimization processing, and after the input is finished, relevant information such as semen counting, semen regulation and the like can be input according to the operation sequence. For another example, when the information of the semen and the ovum is filled, the interface opened again and displayed by the input interface is the interface 'embryo culture' after the ovum is fertilized into an embryo in the next step.
Therefore, the invention can carry out interface display and provide operation prompt through the preset flow, can standardize information input, ensures no information omission, ensures correct operation sequence and ensures information standardization.
In step 203, relevant information associated with the current patient is displayed on the information display and input interface, and the operator is prompted with information, notes and content of the next operation.
For example, clicking on an embryo culture displays all relevant information and cues associated with the embryo culture on the embryo culture interface.
For example, the operator is prompted to input information related to sperm optimization processing, and after the input is completed, the information related to sperm counting, sperm regulation and the like can be input according to the operation sequence.
Therefore, the step can actively display the operation prompt related to the patient, reduce unnecessary operation or error operation of the operator, ensure no information omission, ensure correct operation sequence and ensure information standardization.
In step 204, the current data input by the operator according to the operation prompt is obtained, and the data and the operation information are recorded.
In step 205, according to the current data and the historical data, the related reference data is calculated according to the preset logic or the preset algorithm, and the feedback prompt is displayed for the reference of the operator.
For example, embryo scores can be automatically given according to historical records for operators to refer to, and the operators are prompted to carry out different operations according to different current growth and development states of the embryos, so that real-time decision assistance of a computer is realized, and quality control of an embryo laboratory is better carried out.
For example, the recommended sperm density requirements can be automatically calculated for operator reference. The fertilization pool is a culture pool for co-culturing sperms and oocytes, the volumes of the fertilization pools can be greatly different under different conditions, and fertilization can be carried out in a 35mm culture dish, a 1ml or larger pool or a 0.1ml liquid drop; the size and density of the sperms in the fertilization pool are closely related to the volume of the fertilization pool. Therefore, the preset logic of the invention can be set to automatically calculate the suggested requirements of sperm density according to the volume of the fertilization pool for the reference of operators, thereby saving the manual calculation step of the operators.
Also for example, a timeout reminder may be made. Before ova are collected from female patients, a step of injecting HCG (Human Chorionic Gonadotropin) is performed, and the time of HCG injection is recorded. The embryo laboratory operator should refer to the time of injecting HCG (generally about 40 hours after HCG injection for insemination) when putting the sperm and the ovum of the couple of the patient together for insemination, and if the time is exceeded, the preset logic of the invention is set to remind the operator to operate as soon as possible according to the detected overtime.
The invention can also calculate the setting parameters in the form displayed by the interface according to the setting algorithm. For example:
1. with respect to repetition period
MII (repetition period) = PN0 (score PN 0) + PN2 (score PN 2) + PN3 (score PN 3)
Wherein the number of MIIs in the repetition period is the sum of the numbers scored as PN0, PN2 and PN 3.
2. With respect to number of ova and inseminations
ferNum (number of inseminates) = optNum (number of eggs obtained) -proNum (number of eggs provided) -fronnnm (number of frozen eggs) + unfromnum (number of thawed eggs)
Wherein, the insemination number is equal to the number of the obtained eggs minus the number of the supplied eggs, the number of the frozen eggs plus the unfreezing number.
3. Regarding number of embryos cultured
Number of embryo cultures = number of fertilized eggs taken-number of discarded microinjection
4. Regarding the incubation time and the sperm incubation time
Culture time = insemination time-aspiration time
Sperm culture time = insemination time-semen handling time
In step 206, the adjustment data that the operator adjusts the input in real time according to the interaction information is obtained, and the data operation information is recorded.
In step 205, calculating relevant reference data according to the current data and the historical data and according to a preset logic or a preset algorithm, and displaying a feedback prompt for an operator to refer to includes:
performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis according to the current data and the historical data;
and displaying the analysis result as a feedback prompt.
It can be found that the embodiment of the invention can utilize a tablet personal computer of a checking system existing in a laboratory operation workstation to input relevant information of a patient sample in real time, and the relevant information is interacted with an operator in real time through preset logic or algorithm, for example, embryo scoring can be automatically given according to historical records, the operator is prompted to carry out different operations according to the current growth and development state of the embryo, and the like, so that the real-time auxiliary decision making of a computer is realized, and the quality control of an embryo laboratory is better carried out. According to the scheme provided by the invention, the data can be input in real time to improve the data accuracy and the input efficiency, the operation of an operator can be carried out according to the quality control requirement through real-time data interaction, decision support can be provided for the operator according to the latest data and historical data of the input sample, and the experimental operation is more standardized and accurate.
Various quality control analyses of the present invention are described in further detail below.
The invention mainly divides the quality control into: 1) Controlling the quality of personnel; 2) Controlling the quality of the culture solution; 3) Controlling time quality; 4) Controlling the quality of the workload; 5) Controlling the quality of equipment; 6) And (5) quality control of consumables.
The following description will be made for each control item:
1) Quality control of personnel
Aiming at personnel quality control, the invention can control by dividing two attributes of a checker and an operator. The quality control of the personnel can be divided into two parts of personal workload and working effect.
The personnel quality control analysis mainly analyzes the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator.
Personal workload: the method comprises the steps of recording attributes of an operator and a verifier, recording who does a certain work, which item is an operation object of the work, and how long the operation time is, and automatically analyzing what the certain operator or verifier does in a period of time.
The working effect is as follows: the recorded work effects include the embryo culture effect, the excellent embryo, the transplantation condition and the like, and the conditions of each embryo and after the transplantation and the like. Each work effect corresponds to an associated operation. For example, the operator's object of operation is embryo culture, corresponding to the embryo culture effect; the operator's object of operation is embryo transfer, and the corresponding is the embryo transfer effect.
By way of example, for example: 1. each laboratory operation corresponds to an operator, indicating that the operator is performing the operation. 2. Each operator is provided with operation information to be recorded when performing laboratory operations. 3. After each operation, there are corresponding effects of culture, excellent embryo or transplantation. 4. After a period of time, the system can automatically extract the workload of the operator, the quality of the influence of the workload on the embryo laboratory, whether the operation of the operator meets the specification or not, and the like. 5. The manager can obtain the working condition of the operator by checking the data automatically extracted by the system to analyze the data.
2) Quality control of culture solution
Aiming at the quality control of the culture solution, the method can be divided into two parts of culture solution parameter recording and culture effect recording.
The culture solution quality control analysis is mainly to compare and analyze culture solution parameter records and culture effect records of different culture solutions to determine a culture solution with a good culture effect and the like.
Culture parameters: it is important to note under what brand of culture medium a certain embryo is cultured.
The culture effect is as follows: the conditions of embryo culture are described, and the final effect of culturing embryos in the culture liquid is described.
By way of example, for example: 1. in the case of otherwise identical conditions, embryos were recorded for culture under different brand media. 2. After a period of time, the cultured embryos were observed and embryo scores were given. 3. By comparing the culture conditions of embryos, the method judges which effect of the culture solution of different brands is better or needs to eliminate which culture solution.
3) Time quality control
Time control, which is a time limitation for some procedures, requires knowledge of at least the start time and the end time, e.g., microinjection, which is typically specified to be completed within 41 hours.
The time quality control analysis is mainly used for analyzing the time distribution conditions of different operations according to the recorded time points of the start and the end of each operation and the operation time limit.
Time quality control: the system records the point in time of each operation so that it can be determined which operation is not completed within a specified time and at which operation step the problem may occur at each operation stage.
By way of example, for example: 1. ICSI (Intracytoplasmic sperm injection) was performed, typically specified to be completed within 41 hours. 2. In the case of paper recording, it is difficult to know whether the time is completed within this time period, and it is necessary to record the start time and the end time using the terminal device. 3. For example, when the operation is started, the time points of ovum and semen are recorded, and then semen culture and ovum culture are carried out, after a period of time, when ICSI operation is carried out, the time point of starting ICSI operation is recorded, and when fertilization is completed, the time of completion is recorded. 4. In the ICSI operation, if a problem occurs, the time points are analyzed according to the recorded information, so that the time delay in the stage is known, the influence caused by the operation is positioned, and the error caused by the error in the stage or the operation error caused by the operator is judged according to other quality control analysis. If the operator is wrong, the quality control of the operator and the quality control of the workload are analyzed, and the reason why the operator has the mistake is judged, so that the problem is solved conveniently.
4) Workload quality control
Aiming at the quality control of the workload, the workload and the working effect (the culture effect, the excellent embryo and the transplantation condition and the like) of the workers can be monitored.
The workload quality control analysis is mainly to analyze the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier.
Workload: in laboratory operation, the attributes of an operator and a verifier are recorded, the work is operated by the operator, the project is operated by the work, the operation time is long, and the operator or the verifier can automatically analyze what the operator or verifier does in a certain period of time.
The working effect is as follows: the recorded work effects comprise the conditions of embryo culture effect, excellent embryo, transplantation condition and the like, and the conditions of each embryo and after transplantation and the like. Each work effect corresponds to an associated operation. For example, the operator's object of operation is embryo culture, corresponding to the embryo culture effect; the operation object of the operator is embryo transplantation, and the corresponding is embryo transplantation effect.
By way of example, for example: 1. the workload quality control mainly judges how the efficiency and the effect of the working personnel are under different workload conditions. 2. Through the data provided by the system, whether the working quality of the staff is higher than that of other people can be analyzed.
5) Quality control of equipment
Aiming at equipment quality control, recording parameters which need to meet the standard of the equipment, recording whether the fluctuation of the parameter values meets the standard requirement in a certain period of time, if not, considering what factors cause, and judging whether to need to replace new equipment and the like.
The equipment quality control analysis is mainly used for analyzing whether the equipment meets the equipment quality control requirement or not according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation.
6) Quality control of consumable
And the quality control of consumables mainly records which equipment is consumed by each project.
The consumable quality control analysis mainly analyzes whether the consumable use meets the consumable quality control requirement according to the consumable quantity, the consumable name and the consumable consumption standard.
The information display and input interface of the present invention is further described below and may include: semen processing, ovum collection, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing or embryo transplantation and other functional interfaces.
The invention can set the sperm source as three parts, namely, the identity, the attribute (frozen/fresh sperm) and the source (semen/testicular tissue/epididymal tissue). The invention can input information data manually for all surgeons or nurses, and can also input information data in a voice mode.
In the invention, as for the semen receiver, the flow can be customized, and one semen receiver is added, which corresponds to the semen receiver for IVF semen processing.
The present invention is illustrated in the setting of IVF semen treatment as shown in table 1 below, and with reference to fig. 3, fig. 3 is a schematic view of a portion of the interface region of an information display and input interface for semen treatment according to one embodiment of the present invention:
TABLE 1
The IVF quality control method of the present invention is described in detail above, and the IVF terminal device and system of the present invention are described correspondingly below.
Fig. 4 is a schematic block diagram of an IVF terminal device according to an embodiment of the present invention.
Referring to fig. 4, an IVF terminal device 40 includes: the display module 41, the first prompting module 42, the first obtaining module 43, the second prompting module 44, and the second obtaining module 45.
And the display module 41 is configured to display an information display and input interface associated with the operation object according to a preset flow in the terminal device. Wherein, the operation object can be a patient for assisted reproduction.
A first prompt module 42, configured to display an operation prompt associated with the operation object on the information display and input interface displayed by the display module 41. For example, clicking on a patient's embryo culture displays all relevant information and prompts associated with the patient's embryo culture on the embryo culture interface.
A first obtaining module 43, configured to obtain and record current data input according to the operation prompt of the first prompting module 42. The input may comprise a voice input or a manual input, etc.
And a second prompt module 44, configured to display a feedback prompt according to a preset logic or a preset algorithm according to the current data and the historical data acquired by the first acquisition module 43.
And a second obtaining module 45, which obtains and records the adjustment data input according to the feedback prompt of the second prompting module 44.
As can be seen from this embodiment, in the scheme of the present invention, after the terminal device displays the information display and input interface associated with the operation object according to the preset flow, the operation prompt associated with the operation object is displayed on the information display and input interface; after the current data input according to the operation prompt is obtained and recorded, the feedback prompt can be displayed according to the current data and the historical data and according to a preset logic or a preset algorithm. Therefore, the scheme of the invention can reduce information input errors in laboratory operation, can also guide the specific operation of the operator through real-time data interaction, guides the operator to do different responses and operations in a standardized way according to preset logic and interactive data, reduces unnecessary operations or wrong operations of the operator, records the specific operation of the operator and gives a prompt to make the experimental operation more standardized and accurate, thereby realizing computer-aided decision making to a certain extent, finely managing the details of laboratory sample operation, sample conditions and the like which cannot be managed in place in the past, and realizing the wider quality control of the embryo laboratory.
Fig. 5 is another schematic block diagram of an IVF terminal device according to an embodiment of the present invention.
Referring to fig. 5, an IVF terminal device 50 includes: the system comprises a display module 41, a first prompting module 42, a first obtaining module 43, a second prompting module 44, a second obtaining module 45 and a positioning module 46.
The IVF terminal equipment can be a tablet computer in the IVF verification system, or other terminal equipment and the like. That is, the tablet computer of the conventional IVF checking system can be utilized, so that the entry is more convenient than the case that one computer is arranged beside the tablet computer, and because some operating positions in a laboratory are smaller and computers for entry cannot be added beside the laboratory, the tablet computer of the conventional IVF checking system can be directly utilized more conveniently.
The functions of the display module 41, the first prompt module 42, the first obtaining module 43, the second prompt module 44, and the second obtaining module 45 may be described with reference to fig. 4, and are not described herein again.
The positioning module 46 is configured to position a current operation object. The current operation object can be positioned by manually selecting the terminal equipment or automatically positioning the chip.
The information display and input interface associated with the operation object displayed by the display module 41 includes: functional interfaces for semen handling, egg retrieval, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or embryo transfer associated with patients assisting reproduction.
Wherein the second prompting module 44 may include: an analysis sub-module 441 and a feedback sub-module 442.
And the analysis submodule 441 is used for performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis according to the current data and the historical data and according to a preset logic or a preset algorithm.
And the feedback sub-module 442 is configured to display the analysis result of the analysis sub-module 441 as a feedback prompt.
For example, the second prompting module 44 may automatically give embryo scores according to historical records, and prompt an operator to perform different operations according to the current growth and development state of the embryo, so as to implement real-time decision assistance by a computer and better perform quality control of an embryo laboratory.
The analysis sub-module 441 may further include: a personnel quality control analysis submodule, a culture solution quality control analysis submodule, a time quality control analysis submodule, a workload quality control analysis submodule, an equipment quality control analysis submodule or a consumable quality control analysis submodule (not shown in the figure).
The personnel quality control analysis sub-module performs personnel quality control analysis, and can analyze the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator;
the culture solution quality control analysis submodule performs culture solution quality control analysis, and can perform comparative analysis according to culture solution parameter records and culture effect records of different culture solutions to determine a culture solution with a good culture effect;
the time quality control analysis sub-module performs time quality control analysis, and can analyze the time distribution conditions of different operations according to the recorded time points of the start and the end of each operation and the operation time limit;
the workload quality control analysis sub-module performs workload quality control analysis, and can analyze the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier;
the equipment quality control analysis submodule performs equipment quality control analysis, and can analyze whether the equipment meets the equipment quality control requirement or not according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation;
the consumable quality control analysis submodule performs consumable quality control analysis, and whether the analysis consumable use meets the consumable quality control requirement can be determined according to the consumable quantity, the consumable name and the consumable consumption standard.
Fig. 6 is a schematic block diagram of an IVF quality control system according to an embodiment of the present invention.
Referring to fig. 6, an IVF quality control system 60, comprising: terminal device 61, server 62. Wherein the terminal 61 may be an IVF terminal.
The terminal device 61 is used for displaying an information display and input interface associated with the operation object according to a preset flow at the terminal device; displaying an operation prompt associated with the operation object on the information display and input interface; and acquiring current data input according to the operation prompt, recording and sending the current data to the server 62, receiving a feedback prompt generated by analyzing the current data and the historical data sent by the server 62 according to the terminal device 61, and displaying the feedback prompt on an information display and input interface.
And the server 62 is configured to receive the current data sent by the terminal device 61, analyze the current data and the historical data to generate a feedback prompt, and send the feedback prompt to the terminal device 61.
Wherein, the terminal device 61 obtains the adjustment data input according to the feedback prompt, and records or sends the adjustment data to the server 62.
The server 62 may include: an analysis sub-module 621 and a sending sub-module 622.
The analysis submodule 621 is configured to perform quality control analysis of personnel, quality control analysis of culture fluid, quality control analysis of time, quality control analysis of workload, quality control analysis of equipment, or quality control analysis of consumables according to a preset logic or a preset algorithm based on the current data and the historical data after receiving the current data sent by the terminal device 61, and generate a feedback prompt;
the sending submodule 622 is configured to send the feedback prompt of the analysis submodule 621 to the terminal device 61.
It should be noted that the analysis submodule 621 in the server 62 may also include: the functions of the personnel quality control analysis submodule, the culture solution quality control analysis submodule, the time quality control analysis submodule, the workload quality control analysis submodule, the equipment quality control analysis submodule or the consumable quality control analysis submodule (not shown in the figure) can be referred to the description of the figure 5, and the principles are similar.
The more detailed function description of each module refers to the description of the method part, and is not repeated here.
The technical solution according to the present invention has been described in detail hereinabove with reference to the accompanying drawings.
Those of ordinary skill in the art will understand that: the invention is not to be considered as limited to the specific embodiments thereof, but is to be understood as being modified in all respects, all changes and equivalents that come within the spirit and scope of the invention.
Claims (10)
1. An IVF quality control method, comprising:
displaying an information display and input interface associated with the operation object on the terminal equipment according to a preset flow;
displaying an operation prompt associated with the operation object on the information display and input interface;
acquiring and recording current data input according to the operation prompt;
displaying a feedback prompt according to the current data and the historical data and according to a preset logic or a preset algorithm, wherein the feedback prompt comprises the following steps: according to the current data and the historical data, calculating to obtain related reference data according to a preset logic or a preset algorithm, performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis, taking an analysis result and the related reference data as feedback prompts, and displaying the feedback prompts;
acquiring and recording adjustment data input according to the feedback prompt;
wherein:
the relevant reference data comprises one or more of sperm density, repetition period, number of inseminations, number of embryo cultures, culture time, and sperm culture time;
the performing personnel quality control analysis comprises: analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator; or the like, or, alternatively,
the performing culture solution quality control analysis comprises: performing comparative analysis according to the culture solution parameter records and the culture effect records of different culture solutions to determine a culture solution with a good culture effect; or the like, or, alternatively,
the performing the time quality control analysis comprises: analyzing the time distribution conditions of different operations according to the recorded time points of the start and the end of each operation and the operation time limit; or the like, or, alternatively,
the performing the workload quality control analysis comprises: analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier; or the like, or a combination thereof,
the performing of the equipment quality control analysis comprises: analyzing whether the equipment meets the quality control requirement of the equipment or not according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation; or the like, or, alternatively,
the performing of consumable quality control analysis comprises: and analyzing whether the consumable use meets the consumable quality control requirement or not according to the consumable quantity, the consumable name and the consumable consumption standard.
2. The method according to claim 1, wherein before the terminal device displays the information display and input interface associated with the operation object according to the preset flow, the method further comprises:
and positioning the current operation object through the terminal equipment.
3. The method according to claim 2, wherein the locating the current operation object through the terminal device comprises:
and positioning the current operation object of the terminal equipment in a manual selection or chip automatic positioning mode.
4. The method of claim 1, wherein:
the operation object comprises a patient for assisted reproduction;
the information display and input interface associated with the operation object comprises: a functional interface to semen handling, egg aspiration, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or embryo transfer associated with the assisted reproductive patient.
5. The method of claim 1, wherein:
the input includes voice input or manual input.
6. The method of claim 1, wherein:
the terminal equipment is a tablet computer in the IVF checking system.
7. An IVF terminal device, comprising:
the display module is used for displaying an information display and input interface associated with the operation object on the terminal equipment according to a preset flow;
the first prompt module is used for displaying an operation prompt related to the operation object on an information display and input interface displayed by the display module;
the first acquisition module is used for acquiring and recording current data input according to the operation prompt of the first prompt module;
the second prompting module comprises an analysis submodule and a feedback submodule;
the analysis submodule is used for calculating relevant reference data according to the current data and the historical data acquired by the first acquisition module and a preset logic or a preset algorithm, and performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis;
the feedback submodule is used for taking the analysis result of the analysis submodule and the related reference data as a feedback prompt and displaying the feedback prompt;
the second acquisition module is used for acquiring and recording the adjustment data input according to the feedback prompt of the second prompt module;
wherein:
the related reference data calculated by the analysis submodule comprise one or more of sperm density, repetition period, insemination number, embryo culture number, culture time and sperm culture time;
the analysis submodule includes:
the personnel quality control analysis sub-module is used for carrying out personnel quality control analysis and analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator; or may also include the use of,
the culture solution quality control analysis submodule is used for performing culture solution quality control analysis, performing comparative analysis according to culture solution parameter records and culture effect records of different culture solutions, and determining a culture solution with a good culture effect; or may also include the step of,
the time quality control analysis submodule is used for carrying out time quality control analysis and analyzing the time distribution conditions of different operations according to the recorded time points of the start and the end of each operation and the operation time limit; or may also include the step of,
the workload quality control analysis submodule is used for carrying out workload quality control analysis and analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier; or may also include the step of,
the equipment quality control analysis submodule is used for carrying out equipment quality control analysis and analyzing whether the equipment meets the equipment quality control requirement or not according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation; or may also include the step of,
and the consumable quality control analysis submodule is used for performing consumable quality control analysis, and analyzing whether the consumable use meets the consumable quality control requirement or not according to the consumable quantity, the consumable name and the consumable consumption standard.
8. The apparatus of claim 7, further comprising:
and the positioning module is used for positioning the current operation object.
9. The apparatus according to claim 7 or 8, characterized in that:
the information display and input interface which is displayed by the display module and is associated with the operation object comprises: functional interfaces for semen handling, egg retrieval, embryo culture, microprocessing, embryo freezing, microinjection, sperm freezing, or embryo transfer associated with patients assisting reproduction.
10. An IVF quality control system, comprising:
the terminal equipment is used for displaying an information display and input interface associated with the operation object according to a preset flow; displaying an operation prompt associated with the operation object on the information display and input interface; acquiring current data input according to the operation prompt, recording and sending the current data to a server, receiving a feedback prompt generated by analyzing the current data and the historical data sent by the server according to the terminal equipment, and displaying the feedback prompt on an information display and input interface;
the server is used for receiving the current data sent by the terminal equipment, calculating relevant reference data according to the current data and the historical data, performing personnel quality control analysis, culture solution quality control analysis, time quality control analysis, workload quality control analysis, equipment quality control analysis or consumable material quality control analysis, taking an analysis result and the relevant reference data as feedback prompts, and sending the feedback prompts to the terminal equipment; wherein:
the relevant reference data comprises one or more of sperm density, repetition period, number of inseminations, number of embryo cultures, time of culture, and sperm culture time;
the performing personnel quality control analysis comprises: analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the verifier and the operator; or the like, or, alternatively,
the performing culture solution quality control analysis comprises: performing comparative analysis according to the culture solution parameter records and the culture effect records of different culture solutions to determine a culture solution with a good culture effect; or the like, or, alternatively,
the performing the time quality control analysis comprises: analyzing the time distribution conditions of different operations according to the recorded time points of the start and the end of each operation and the operation time limit; or the like, or, alternatively,
the performing the workload quality control analysis comprises: analyzing the workload and the working effect of the operator and the verifier according to the operation quantity, the operation object, the operation time and the cultivation effect of the operation object of the operator and the verifier; or the like, or, alternatively,
the performing of the equipment quality control analysis comprises: analyzing whether the equipment meets the quality control requirement of the equipment or not according to the standard parameters of the equipment and the fluctuation condition of the parameters of the equipment during operation; or the like, or a combination thereof,
the performing of consumable quality control analysis comprises: and analyzing whether the consumable use meets the consumable quality control requirement or not according to the consumable quantity, the consumable name and the consumable consumption standard.
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