CN108982201A - A kind of air bath temperature control device and system - Google Patents

A kind of air bath temperature control device and system Download PDF

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Publication number
CN108982201A
CN108982201A CN201811203450.5A CN201811203450A CN108982201A CN 108982201 A CN108982201 A CN 108982201A CN 201811203450 A CN201811203450 A CN 201811203450A CN 108982201 A CN108982201 A CN 108982201A
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China
Prior art keywords
temperature control
control device
sample
air bath
bath temperature
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CN201811203450.5A
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Chinese (zh)
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CN108982201B (en
Inventor
朱富春
陈俊飞
李国平
郝效禹
韩绪春
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Wuxi Ke Zhi Da Technology Co Ltd
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Wuxi Ke Zhi Da Technology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42Low-temperature sample treatment, e.g. cryofixation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44Sample treatment involving radiation, e.g. heat
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00Control of temperature
    • G05D23/19Control of temperature characterised by the use of electric means

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Testing Resistance To Weather, Investigating Materials By Mechanical Methods (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Abstract

The present invention relates to temperature to control art field, specifically disclose a kind of air bath temperature control device, wherein, the air bath temperature control device includes: shell, temperature control mould group, temperature sensor and rotary drive mechanism, the temperature control mould group, temperature sensor and rotary drive mechanism are arranged in the shell, and the temperature control mould group and rotary drive mechanism can be communicated to connect with control device;The rotary drive mechanism can drive the sample to be processed to be rotated under the control of the control device for carrying sample to be processed;Temperature of the temperature sensor for sample to be processed described in real-time monitoring;The temperature control mould group is for being heated or being freezed to the sample to be processed under the control of the control device, and enough adjustment that heating mode or refrigeration mode are carried out according to the temperature of the sample to be processed.The invention also discloses a kind of air bath temperature control systems.The advantage that air bath temperature control device provided by the invention has heating or refrigerating speed is fast and loss is small.

Description

A kind of air bath temperature control device and system
Technical field
The present invention relates to technical field of temperature control more particularly to a kind of air bath temperature control device and including the air bath temperature Control the air bath temperature control system of device.
Background technique
Detection technique is commonly used in analysis detection biochemistry detection, enzyme linked immunosorbent detection, polymerase chain reaction etc., for short The accuracy and consistency that time completes detection, improves detection, often need to provide stable reaction temperature condition, common heating Mode has a multiple forms such as air bath, water-bath, metal bath, but that there are power consumptions is big for conventional heating method, and pre- heat utilization efficiency is low, warm The problems such as uniformity is poor is spent, warming and cooling rate changes the disadvantages of slow.
Therefore, how a kind of heating is provided or refrigerating speed is fast and loss is small temperature control system becomes those skilled in the art Technical problem urgently to be resolved.
Summary of the invention
The present invention is directed at least solve one of the technical problems existing in the prior art, a kind of air bath temperature control device is provided And the air bath temperature control system including the air bath temperature control device, to solve the problems of the prior art.
As the first aspect of the invention, a kind of air bath temperature control device is provided, wherein the air bath temperature control device It include: shell, temperature control mould group, temperature sensor and rotary drive mechanism, the temperature control mould group, temperature sensor and rotation driving Mechanism is arranged in the shell, and the temperature control mould group and rotary drive mechanism can be communicated to connect with control device;
The rotary drive mechanism for carrying sample to be processed, and can drive under the control of the control device it is described to Processing sample is rotated;
Temperature of the temperature sensor for sample to be processed described in real-time monitoring;
The temperature control mould group is used to that the sample to be processed to be heated or be freezed under the control of the control device, and enough The adjustment of heating mode or refrigeration mode is carried out according to the temperature of the sample to be processed.
Preferably, the shell includes: lower casing, upper shell, upper cover plate, lower inner cover and inward upper cover, the lower casing, on Shell and upper cover plate constitute exocoel, and the lower inner cover and the inward upper cover constitute inner cavity, and the exocoel is mutually interconnected with the inner cavity It is logical.
Preferably, the temperature control mould group includes fan, the temperature control module for being located at the exocoel and setting gradually from top to bottom With overheat protector temperature controller, the temperature control module is connected to by the aperture on the upper shell with the inner cavity.
Preferably, the temperature control module includes any one in Peltier, Electric radiant Heating Film, heating tube and ptc heater.
Preferably, the rotary drive mechanism includes rotation motor and sample fixed structure, the rotation motor with it is described The connection of sample fixed structure, the rotation motor are used to communicate to connect with the control device, and the sample fixed structure is used for The sample to be processed is carried, the sample fixed structure is located in the inner cavity, and the rotation motor is located at outside the shell, And it is connect with the lower casing.
Preferably, the making material of the lower casing, upper shell and upper cover plate includes PBT material.
Preferably, the making material of the lower inner cover and the inward upper cover includes aluminium alloy.
Preferably, the making material of the lower inner cover and the inward upper cover includes copper alloy.
As the second aspect of the invention, a kind of air bath temperature control system is provided, wherein the air bath temperature control system Including control device and previously described air bath temperature control device, the air bath temperature control device and the control device communication link It connects, the air bath temperature control device can realize the heating or refrigeration to sample to be processed under the control of the control device.
Temperature control mould group, temperature sensor and rotation driving is arranged in air bath temperature control device provided by the invention in shell Mechanism carries sample to be processed by rotary drive mechanism, and is able to drive sample rotates to be processed, then passes through temperature sensing The temperature of device real-time monitoring sample to be processed, temperature control mould group can carry out heating mode or refrigeration according to the temperature of sample to be processed The adjustment of mode, the final heating or refrigeration realized to sample to be processed, air bath temperature control device provided by the invention, which has, to be added Heat or the advantage that refrigerating speed is fast and loss is small.
Detailed description of the invention
The drawings are intended to provide a further understanding of the invention, and constitutes part of specification, with following tool Body embodiment is used to explain the present invention together, but is not construed as limiting the invention.In the accompanying drawings:
Fig. 1 is the structural block diagram of air bath temperature control device provided by the invention.
Fig. 2 is the schematic perspective view of air bath temperature control device provided by the invention.
Fig. 3 is the specific design of part schematic diagram of air bath temperature control device provided by the invention.
Fig. 4 is the specific schematic diagram of internal structure of air bath temperature control device provided by the invention.
Fig. 5 is that the air heat circulation principle of air bath temperature control device provided by the invention illustrates schematic diagram.
Fig. 6 is the heat cycles schematic diagram of internal structure of air bath temperature control device provided by the invention.
Fig. 7 is that the temperature control cavity upper half of air bath temperature control device provided by the invention moves up schematic diagram.
Fig. 8 is the temperature control cavity lower half Forward schematic diagram of air bath temperature control device provided by the invention.
Fig. 9 is the structural block diagram of air bath temperature control system provided by the invention.
Specific embodiment
Below in conjunction with attached drawing, detailed description of the preferred embodiments.It should be understood that this place is retouched The specific embodiment stated is merely to illustrate and explain the present invention, and is not intended to restrict the invention.
As the first aspect of the invention, a kind of air bath temperature control device is provided, wherein as shown in Figure 1, the air Bathing temperature control device 10 includes: shell 100, temperature control mould group 200, temperature sensor 300 and rotary drive mechanism 400, the temperature control Mould group 200, temperature sensor 300 and rotary drive mechanism 400 are arranged in the shell 100,200 He of temperature control mould group Rotary drive mechanism 400 can be communicated to connect with control device;
The rotary drive mechanism 400 can drive institute for carrying sample to be processed under the control of the control device Sample to be processed is stated to be rotated;
Temperature of the temperature sensor 300 for sample to be processed described in real-time monitoring;
The temperature control mould group 200 is used to that the sample to be processed to be heated or be freezed under the control of the control device, And enough adjustment that heating mode or refrigeration mode are carried out according to the temperature of the sample to be processed.
Temperature control mould group, temperature sensor and rotation driving is arranged in air bath temperature control device provided by the invention in shell Mechanism carries sample to be processed by rotary drive mechanism, and is able to drive sample rotates to be processed, then passes through temperature sensing The temperature of device real-time monitoring sample to be processed, temperature control mould group can carry out heating mode or refrigeration according to the temperature of sample to be processed The adjustment of mode, the final heating or refrigeration realized to sample to be processed, air bath temperature control device provided by the invention, which has, to be added Heat or the advantage that refrigerating speed is fast and loss is small.
As the specific embodiment of the shell 100, as shown in Figures 2 and 3, the shell 100 includes: lower casing 101, upper shell 102, upper cover plate 103, lower inner cover 104 and inward upper cover 105, the lower casing 101, upper shell 102 and upper cover plate 103 constitute exocoel, and the lower inner cover 104 and the inward upper cover 105 constitute inner cavity, and the exocoel and the inner cavity are interconnected.
Specifically, inward upper cover 105 is installed to the lower inside of shell 102, and temperature control mould group 200 is installed to shell 102 Upper inner, upper cover plate 103 is installed to the top of shell 102, constitutes the upper half of temperature control cavity together;Lower inner cover 104 is pacified It is attached to 101 upper inner of lower casing, constitutes the lower half of temperature control cavity together.The fixing end of temperature sensor 300 upward is mounted on On mounting structure inside upper shell 102, temperature sensing end directed downwardly is placed in inner cavity.
As the specific embodiment of the temperature control mould group 200, as shown in Figures 2 to 4, the temperature control mould group 200 includes Fan 201, temperature control module 202 and the overheat protector temperature controller 203 set gradually positioned at the exocoel and from top to bottom, the temperature Control module 202 is connected to by the aperture on the upper shell 102 with the inner cavity.
Preferably, the temperature control module 202 includes any one in Peltier, Electric radiant Heating Film, heating tube and ptc heater Kind.
Specifically, for fan 201 mounted in the upper surface of temperature control module 202, overheat protector temperature controller 203 is mounted on temperature control module 202 side is close together with temperature control module 202.Entire temperature control mould group 200 is in upper shell.Overheat protector temperature controller 203 effect is a kind of protection to causing temperature control module temperature excessively high due to 201 non-normal working of fan.In concrete application In, fan 201 and temperature control module 202 work at the same time, and the air for being heated or being freezed by temperature control module 202 is blowed to temperature by fan 201 It controls intracavitary, makes to be heated or the air that freezes forms circulating for orientation between inner cavity and exocoel.
In order to improve the uniformity of temperature control, the air bath temperature control fills 10 and is provided with rotary drive mechanism 400, as rotation The specific embodiment of driving mechanism 400, the rotary drive mechanism 400 include rotation motor 401 and sample fixed structure 402, the rotation motor 401 is connect with the sample fixed structure 402, and the rotation motor 401 is used to fill with the control Communication connection is set, the sample fixed structure 402 is for carrying the sample to be processed 500, the sample fixed structure 402 In the inner cavity, the rotation motor 401 is located at outside the shell 100, and connect with the lower casing 101.
Specifically, rotary drive mechanism 400 is made of rotation motor 401 and sample fixed structure 402.Sample fixed structure 402 in inner cavity, its main function is fixed sample to be processed 500, is in sample 500 to be processed in inner cavity.Rotation is driven The main purpose of motivation structure 400 is that sample is driven to make rotating motion, same when sample is heated or freezes in temperature control cavity When make rotating motion so that the consistency of sample different location temperature is more preferable.
In a particular application, the upper half of temperature control cavity can be used as an entirety and move up and down relative to lower half, from And realize the opening and closing movement up and down of entire temperature control cavity;Horizontal fortune is done relative to the upper half as a whole in the lower half of temperature control cavity It is dynamic, it is staggered or merges position so as to realize that temperature control cavity or more two parts are in the horizontal direction, it, can be in staggered positions Sample to be processed is facilitated to be placed in temperature control cavity.
Specifically, the making material of the lower casing, upper shell and upper cover plate includes PBT material.
Preferably, the making material of the lower inner cover and the inward upper cover includes aluminium alloy.
Preferably, the making material of the lower inner cover and the inward upper cover includes copper alloy.
It should be noted that material high-low temperature resistant, high flame retardant and the heat insulating ability of lower casing, upper shell and upper cover plate Preferable plastics, such as PBT;Lower inner cover and the good metal material of inward upper cover thermal conductivity, such as aluminium alloy and copper alloy.
It is carried out specifically below with reference to concrete operating principle of the fig. 4 to fig. 6 to air bath temperature control device provided by the invention It is bright.
For in the heating, fan 201 and temperature control module 202 are started to work under control of the control means, temperature control mould Block 202 heats neighbouring air, and the air being heated is blowed to the sample to be processed 500 in heating bore by fan 201, and heat is empty The upper surface that gas againsts sample is directed away from the direction flowing in the center of circle, when hot-air reaches sample outermost end, along outer end face It moves downward, when reaching 500 lower surface of sample to be processed, is moved along sample lower surface to be processed towards the direction close to the center of circle Dynamic, while being blown hot-air downwards due to fan 201, the top of exocoel becomes negative pressuren zone, this underbalance effect in exocoel and It transmits downwards in the outside interlayer that inner cavity is constituted, is communicated when the hot-air moved along sample lower surface reaches lower inner cover with exocoel Hole when, flow into interlayer, and moved upwards along interlayer, temperature constantly declines hot-air during the motion, when cooling sky When gas reaches top, temperature control module 202 is blown by fan 201, again heat cycles.When stream of hot air is through sample, no Sample is given to heat disconnectedly, close to when controlling temperature, control device control is warm when temperature sensor 300 detects temperature near sample It controls module 202 and starts low-power heating, the revolving speed of fan 201 also accordingly reduces, when control temperature is fully achieved in temperature, temperature control Module 202 and fan 201 enter thermostatic control working condition.During the entire process of heating chamber heats up and keeps the temperature, rotation driving Mechanism 400 drives sample to be uniform speed rotation always, the purpose for the arrangement is that keeping the temperature on each position of sample more equal It is even consistent.Similarly, as realized refrigeration mode, temperature control module 202 is adjusted to refrigeration mode, it can be achieved that sample by control device The cooling of product.
As the first, specifically embodiment such as Fig. 7 and Fig. 8 illustrates that sample to be processed is put into temperature control cavity and is heated Or the process of refrigeration.The upper half of temperature control cavity moves up, and then the lower half Forward of temperature control cavity, makes lower half and the upper half of temperature control cavity Portion is in front and back staggered positions, and sample to be processed is fixed on sample fixed structure 402, behind the lower half of following temperature control cavity It moves, the upper half of temperature control cavity moves down so that the top and the bottom of temperature control cavity re-close together;Temperature control module and fan start work Make, rotation drive module drives sample to make rotating motion, and temperature control cavity temperature is quickly raised and lowered at the beginning, works as temperature sensor Close to when controlling temperature, temperature control module 202 starts to be slowly heated or freeze 300 detection temperature, the revolving speed drop of fan 201 Low, when control temperature is fully achieved in temperature, temperature control module 202 and fan 201 enter thermostatic control working condition.
As second, specifically embodiment, air bath temperature regulating device as described above can realize alternating temperature control.It is controlling Under the control of device processed, by switching the mode (heating mode and refrigeration mode) of temperature control module 202, it can be achieved that temperature control device exists Different temperatures section toggles.It is warming up to 90 DEG C as first opened heating mode and keeps 45s, be then turned on refrigeration mode cooling To 60 DEG C and 30s is kept, heating mode is then then turned on and is warming up to 72 DEG C and keeps 30s, by above-mentioned temperature change as one Circulation, by setting recurring number, it can be achieved that the automatic temperature changing of multiple circulations controls.
As the third, specifically embodiment, temperature control module 202 only have heating function, as described above, when sample After Temperature Treatment works, in order to allow the temperature in temperature control cavity to reduce rapidly, it can perform the following operations: the upper half of temperature control cavity Portion moves up, and the upper half and lower half portion is made to start to work from, fan 201, by the hot-air in temperature control cavity from the separation of temperature control cavity Discharge rapidly at mouthful, to achieve the purpose that temperature control cavity and sample is made to cool down rapidly.
As the 4th kind, specifically embodiment, air bath temperature regulating device as described above can realize alternating temperature control.It is different Be that the structure of upper cover plate is made into some changes, do one may be implemented folding similar door structure.When specific works, temperature control The temperature of chamber reaches after higher temperature keeps for a period of time together, and door is opened, and fan is reversely rotated the hot-air in temperature control cavity Temperature control cavity is discharged by door, when temperature drops to lower temperature two, door is closed, into the keeping warm mode of temperature two.Alternating temperature control Temperature number of segment and endless form can according to need specific setting.For door close and open movement can with Electronic control, It can also mechanically realize.
As the second aspect of the invention, a kind of air bath temperature control system is provided, wherein as shown in figure 9, the air Bathing temperature control system 1 includes control device 20 and previously described air bath temperature control device 10, the air bath temperature control device 10 with The control device 20 communicates to connect, and the air bath temperature control device 10 can be realized pair under the control of the control device 20 The heating or refrigeration of sample to be processed.
Temperature control mould group, temperature sensor and rotation driving is arranged in air bath temperature control system provided by the invention in shell Mechanism carries sample to be processed by rotary drive mechanism under control of the control means, and is able to drive sample rotation to be processed Turn, then passes through the temperature of temperature sensor real-time monitoring sample to be processed, temperature control mould group can be according to the temperature of sample to be processed Degree carries out the adjustment of heating mode or refrigeration mode, and the final heating or refrigeration realized to sample to be processed is provided by the invention The advantage that air bath temperature control system has heating or refrigerating speed is fast and loss is small.
It should be understood that air bath temperature-controlling system will not be used alone, it will be integrated into instrument or equipment, so Above-mentioned control device 20 is also integrated into the control module of instrument or equipment, controls air by the control module of instrument or equipment Bathe temperature control system work.
It is understood that the principle that embodiment of above is intended to be merely illustrative of the present and the exemplary implementation that uses Mode, however the present invention is not limited thereto.For those skilled in the art, essence of the invention is not being departed from In the case where mind and essence, various changes and modifications can be made therein, these variations and modifications are also considered as protection scope of the present invention.

Claims (9)

1. a kind of air bath temperature control device, which is characterized in that the air bath temperature control device includes: shell, temperature control mould group, temperature Sensor and rotary drive mechanism, the temperature control mould group, temperature sensor and rotary drive mechanism are arranged in the shell, The temperature control mould group and rotary drive mechanism can be communicated to connect with control device;
The rotary drive mechanism for carrying sample to be processed, and can drive under the control of the control device it is described to Processing sample is rotated;
Temperature of the temperature sensor for sample to be processed described in real-time monitoring;
The temperature control mould group is used to that the sample to be processed to be heated or be freezed under the control of the control device, and enough The adjustment of heating mode or refrigeration mode is carried out according to the temperature of the sample to be processed.
2. air bath temperature control device according to claim 1, which is characterized in that outside the shell includes: lower casing, is upper Shell, upper cover plate, lower inner cover and inward upper cover, the shell, upper shell and upper cover plate constitute exocoel, the lower inner cover and it is described it is upper in Lid constitutes inner cavity, and the exocoel and the inner cavity are interconnected.
3. air bath temperature control device according to claim 2, which is characterized in that the temperature control mould group includes being located at outside described Chamber and the fan set gradually from top to bottom, temperature control module and overheat protector temperature controller, the temperature control module pass through described outer Aperture on shell is connected to the inner cavity.
4. air bath temperature control device according to claim 3, which is characterized in that the temperature control module includes Peltier, electricity Any one in hotting mask, heating tube and ptc heater.
5. air bath temperature control device according to claim 2, which is characterized in that the rotary drive mechanism includes rotation horse Up to sample fixed structure, the rotation motor connect with the sample fixed structure, and the rotation motor is used for and the control Device communication connection processed, for the sample fixed structure for carrying the sample to be processed, the sample fixed structure is located at institute It states in inner cavity, the rotation motor is located at outside the shell, and connect with the lower casing.
6. air bath temperature control device according to claim 2, which is characterized in that the lower casing, upper shell and upper cover plate Making material include PBT material.
7. air bath temperature control device according to claim 2, which is characterized in that the system of the lower inner cover and the inward upper cover It include aluminium alloy as material.
8. air bath temperature control device according to claim 2, which is characterized in that the system of the lower inner cover and the inward upper cover It include copper alloy as material.
9. a kind of air bath temperature control system, which is characterized in that the air bath temperature control system includes control device and claim 1 To air bath temperature control device described in any one of 8, the air bath temperature control device and the control device are communicated to connect, institute Heating or refrigeration to sample to be processed can be realized under the control of the control device by stating air bath temperature control device.
CN201811203450.5A 2018-10-16 2018-10-16 Air bath temperature control device and system Active CN108982201B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112094740A (en) * 2020-09-25 2020-12-18 壹宏(深圳)基因有限公司 PCR amplification method and PCR amplification device
CN113533229A (en) * 2021-06-25 2021-10-22 华东师范大学 Portable temperature control device of spectrophotometer
CN114227858A (en) * 2021-12-16 2022-03-25 武汉必盈生物科技有限公司 Temperature control system of external fixation 3D printer for fracture

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CN207689940U (en) * 2018-02-09 2018-08-03 深圳市泰嘉电子有限公司 Platelet aggregation instrument thermostat

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CN1545137A (en) * 2003-11-12 2004-11-10 四川大学 Gas-filled annealing furnace
CN101331009A (en) * 2005-11-08 2008-12-24 莫菲克科技股份公司 An arrangement and a method for heating metal objects
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112094740A (en) * 2020-09-25 2020-12-18 壹宏(深圳)基因有限公司 PCR amplification method and PCR amplification device
CN113533229A (en) * 2021-06-25 2021-10-22 华东师范大学 Portable temperature control device of spectrophotometer
CN114227858A (en) * 2021-12-16 2022-03-25 武汉必盈生物科技有限公司 Temperature control system of external fixation 3D printer for fracture

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