CN108969594A - A kind of Chinese materia medica preparation that treating osteoproliferation and preparation method - Google Patents
A kind of Chinese materia medica preparation that treating osteoproliferation and preparation method Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 43
- 239000002398 materia medica Substances 0.000 title claims abstract description 15
- 239000000706 filtrate Substances 0.000 claims abstract description 38
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 35
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 35
- 241000601164 Clematis orientalis Species 0.000 claims abstract description 34
- 241000218176 Corydalis Species 0.000 claims abstract description 34
- 239000002994 raw material Substances 0.000 claims abstract description 23
- 244000189799 Asimina triloba Species 0.000 claims abstract description 22
- 235000006264 Asimina triloba Nutrition 0.000 claims abstract description 22
- 235000009467 Carica papaya Nutrition 0.000 claims abstract description 22
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- 239000000470 constituent Substances 0.000 claims abstract description 8
- 239000006187 pill Substances 0.000 claims abstract description 8
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Abstract
A kind of Chinese materia medica preparation that treating osteoproliferation and preparation method belong to Chinese materia medica preparation and its preparation method.The raw material for preparing its active constituent includes berba aristolochiae mollissimae 12~15, Radix Salviae Miltiorrhizae 15~30, safflower 10~15, Cortex Eucommiae 15~25, radix achyranthis bidentatae 20~25, radix scrophulariae 12~18, the root of Chinese clematis 8~12, pawpaw 20~30, corydalis tuber 10~15.Preparation method is to add water to cook above-mentioned raw materials into extraction, filters, and filtrate is condensed into medicinal extract by merging filtrate；By extract dry, it is prepared into particle, wine liquid, capsule, tablet, pill or oral solution.The beneficial effects of the present invention are: curative for effect, significant effect in terms of invention formulation disc herniation caused by treatment osteoproliferation and osteoproliferation, and curative effect is lasting, does not find adverse reaction and side effect.Fundamentally calcification proliferative fraction and eradicate this disease, it is uneasy to recur.
Description
Technical field:
A kind of Chinese materia medica preparation that treating osteoproliferation and preparation method belong to Chinese materia medica preparation and its preparation method.
Background technique:
Osteoproliferation and intervertebral protrusion are a kind of common diseases, cervical vertebra hyperplasia, shoulder joint hyperplasia, lumbar vertebrae can be divided to increase by position
Life, elbow joint hyperplasia, knee joint hyperplasia, calcaneal hyperplasia etc..Each position osteoproliferation can cause human body corresponding site lesion, give patient
Bring various harm even great pain.As cervical vertebra hyperplasia and intervertebral protrusion can cause neck vision disorder, neck dysaudia, neck
Property coronary heart disease, neck dysarteriotony, dizziness, or even long-term cerebral insufficiency and cause encephalatrophy to cause dementia etc.；Hyperosteogeny (vertebra
Disk is prominent) can cause waist and waist week pain, heavy then pain on the outside of being radiated in buttocks and thigh, care for sciatica extend to it is small
Leg, numbness of lower limbs, or even cause to paralyse；Knee joint hyperplasia then causes gonalgia, joint stuffiness, heavy then have difficulty in taking a step；With
Bone regeneration then causes heel that dare not land, and walking along the street is difficult etc..Osteoproliferation and intervertebral clinical treatment means outstanding are usual
Including massage, microneedle therapy, acupuncture needle therapy, far infrared therapy, traction treatment, operative treatment and drug therapy etc..But face
Bed routine treatment and medication effect are unsatisfactory, even if effectively also difficult lasting；Surgical result is accordingly obvious, but takes
It is few then up to ten thousand with valuableness, more then tens of thousands of or even hundreds of thousands of members, it is most important that there are many unpredictable risks for operation, cause
People talk operation discoloration.
Summary of the invention:
It is lasting that the problem to be solved in the present invention provides a kind of significant effect aiming above insufficient, utmostly mitigates
Patient's pain, low-cost treatment osteoproliferation and intervertebral Chinese materia medica preparation outstanding and its preparation method.Its technology
Scheme is as follows:
The present invention prepare its active constituent raw material include following parts by weight raw material:
Berba aristolochiae mollissimae 12~15, Radix Salviae Miltiorrhizae 15~30, safflower 10~15, Cortex Eucommiae 15~25, radix achyranthis bidentatae 20~25, radix scrophulariae 12~18,
The root of Chinese clematis 8~12, pawpaw 20~30, corydalis tuber 10~15.
Preparation method is 12~15 parts of berba aristolochiae mollissimae, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, Cortex Eucommiae 15~25
Part, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, 8~12 parts of the root of Chinese clematis, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber plus decocting
Extraction is boiled, is filtered, filtrate is condensed into medicinal extract by merging filtrate；By extract dry, it is prepared into particle, wine liquid, capsule, tablet, ball
Agent or oral solution.
Further, the raw material for preparing its active constituent further includes 3~8 parts of Rhizoma Chuanxiong.
Preparation method is 12~15 parts of berba aristolochiae mollissimae, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, Cortex Eucommiae 15~25
Part, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, 8~12 parts of the root of Chinese clematis, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber, Rhizoma Chuanxiong 3
~8 parts add water to cook extraction, and filtrate is condensed into medicinal extract by filtering, merging filtrate；By extract dry, be prepared into particle, wine liquid,
Capsule, tablet, pill or oral solution.
Further, the raw material for preparing its active constituent further includes 5~15 parts of herba taxilli.
Preparation method is 12~15 parts of berba aristolochiae mollissimae, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, Cortex Eucommiae 15~25
Part, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, 8~12 parts of the root of Chinese clematis, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber, Rhizoma Chuanxiong 3
~8 parts, 5~15 parts of herba taxilli add water to cook extraction, and filtrate is condensed into medicinal extract by filtering, merging filtrate；By extract dry, system
For at particle, wine liquid, capsule, tablet, pill or oral solution.
Compared with prior art, the invention has the advantages that:
1, product of the present invention is main former with pure Chinese medicines such as berba aristolochiae mollissimae, Radix Salviae Miltiorrhizae, safflower, Cortex Eucommiae, radix achyranthis bidentatae, the root of Chinese clematis, Rhizoma Chuanxiongs
Material is combined into preparation, curative for effect, significant effect in terms of the disc herniation caused by treatment osteoproliferation and osteoproliferation, and
And curative effect is lasting, does not find adverse reaction and side effect.Fundamentally calcification proliferative fraction and eradicate this disease, it is uneasy to recur.
2, the Chinese medicine material of product of the present invention is not expensive, so manufactured finished product is moderate, low in treatment cost.
3, the present inventor, which takes up a job as a doctor, has been devoted to use in the past 30 years traditional Chinese medicine to doubt miscellaneous chronic disease as clinic
Treatment, especially for many years using pure traditional Chinese medicine treatment osteoproliferation and disc herniation, by of the invention during the last ten years recently
Product treats observation to the pure Chinese medicine of more than 3000 example osteoproliferations and disc herniation patient, it is only necessary to invention formulation is taken,
It is not required to intervention other therapies such as traction treatment, operative treatment, can effectively treat this disease, utmostly mitigates patient's pain, and
And substantially reduce Case treatment expense.
To show that product of the present invention to the therapeutic effect of osteoproliferation and disc herniation, has made system to 3000 patients
Clinical observation:
Diagnostic criteria: osteoproliferation is a kind of since articular cartilage integrity violations and joint margins subcartilaginous osseous lamella are sick
Become, leads to one group of different substantiality disease of joint symptoms and sign.Mainly it is presented with:
Cervical vertebrae hyperosteogeny (Cervical Disk Herniation): neck has a strong sense, snap, limitation of activity, pain often to shoulder and
Upper limb radiation, hand and finger have feeling of numbness, it is also possible to can cause dizziness, angina pectoris, dysphagia etc.；
Lumbar vertebrae hyperosteogeny (protrusion of lumber intervertebral disc): waist aches, distending pain, stiff with tired sense, or even bends over to be limited, also
It will appear local pain, hair deadlock, rear root neuralgia, numbness etc.；
Articulatio genus hyperosteogeny: knee joint sustainability secret anguish, stiff, joint pain distending pain when serious are walked lamely, joint function
Can be limited, the most obvious to squat down, stretching and beading activity has snap sound, and some patientss visible joint hydrops locally has obvious tumefaction, pressure
Pain phenomenon；
Calcaneal hyperplasia: heel dare not land, and walking along the street is difficult.
Effective standard:
Effective: each position is eased based on the symptom of osteoproliferation, pain relief.
Cure: each position is disappeared based on the symptom of osteoproliferation, and pain is eliminated.After curing 2-3, through Clinical X light, film making
It checks, proliferative fraction is thin out, calcification even disappears.It is mainly shown as:
Cervical vertebrae hyperosteogeny (Cervical Disk Herniation): the strong sense of neck, snap disappear, and hand and numbness of fingers sense are eliminated, whole
A physical activity is freely；
Lumbar vertebrae hyperosteogeny (protrusion of lumber intervertebral disc): waist aches, distending pain, stiff with tired sense elimination, bends over freely, office
The symptoms such as portion's pain, hair deadlock, rear root neuralgia, numbness disappear；
Articulatio genus hyperosteogeny: knee joint secret anguish, stiff, joint pain distending pain sense are eliminated, and walking is normal, and function of joint is not
It is restricted, freely, hydrops articuli, local swelling, tenderness phenomenon are also eliminated for stretching and beading activity；
Calcaneal hyperplasia: heel pain is eliminated, and walking along the street is as usual.
Dosage regimen: can be according to each one condition selection capsule, tablet or particle, 3 times a day.Wine liquid two is eaten daily morning and evening
30-50ml is drunk between meal.
Display is investigated in 3000 tested people, is taken product of the present invention two weeks to one month, and about 1800 people are effective, show
Efficiency about 60%；It takes one month to two months, about 2700 people are effective, obvious effective rate about 90%；Take two months to 2 years, about
2800 rule by men more, final cure rate about 95%；There are 5 paralytics, takes product of the present invention 2 years, perform a miraculous cure unexpectedly
?.
Typical case falls ill:
Pass ×, female, 38 years old, on October 23rd, 2003 was medical, and biped calcaneal hyperplasia, biped heel is difficult to land, walking along the street
It is difficult.Product of the present invention oral solution is taken, treatment time 3 months, is had not relapsed so far after healing.
In Guo ×, male, 56 years old, on August 14th, 2008 were medical, hyperosteogeny, disc herniation, and pain in the loins 1 year, compressing was sat
Bone nerve pain numb half a year.Wine liquid a year and a half of the present invention is drunk, is had not relapsed so far after healing.
Li Qiong ×, female, 50 years old, on October 6th, 2012 was medical, cervical vertebra hyperplasia, acutely dizzy, hyperosteogeny, pain in the loins, double knees
Joint hyperplasia, double knee pain are for many years.Product of the present invention pill is taken, treatment time 2 years, is had not relapsed so far after healing.
× quick, male, 43 years old, on October 6th, 2017 was medical, and right shoulder joint hyperplasia, right shoulder and upper arm pain are more than a year.
Product of the present invention particle is taken, half a year treatment time has not relapsed so far after healing.
Specific embodiment:
Embodiment 1:
Invention formulation is made using following raw material:
12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, 8 parts of the root of Chinese clematis, wood
30 parts of melon, 10 parts of corydalis tuber.
The preparation method of invention formulation, key technology are:
1) by 12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, the root of Chinese clematis 8
Part, 30 parts of pawpaw, 10 parts of corydalis tuber plus 5 times of amount water are decocted and are extracted 2 times, 2 hours every time, filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of temperature 70 C, vacuum degree 0.1Mpa；
3) by extract dry, it is ground into fine powder, is prepared into particle with the method in pharmaceutical technology.
Embodiment 2:
Invention formulation is made using following raw material:
15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, 12 parts of the root of Chinese clematis, wood
20 parts of melon, 15 parts of corydalis tuber.
The preparation method of invention formulation, key technology are:
1) by 15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, the root of Chinese clematis 12
Part, 20 parts of pawpaw, 15 parts of corydalis tuber plus 3 times of amount water are decocted and are extracted 3 times, 1 hour every time, filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.25 under the conditions of 80 DEG C of temperature, vacuum degree 0.08Mpa；
3) by extract dry, it is ground into fine powder, pelletizes, is prepared into capsule with the method in pharmaceutical technology.
Embodiment 3:
Invention formulation is made using following raw material:
13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, 10 parts of the root of Chinese clematis, wood
25 parts of melon, 12 parts of corydalis tuber.
The preparation method of invention formulation, key technology are:
1) by 13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, the root of Chinese clematis 10
Part, 25 parts of pawpaw, 12 parts of corydalis tuber plus 4 times of amount water are decocted and are extracted 2 times, 1.5 hours every time, filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of 75 DEG C of temperature, vacuum degree 0.09Mpa；
3) by extract dry, it is ground into fine powder, it is tabletted with the method in pharmaceutical technology.
Embodiment 4:
Invention formulation is made using following raw material:
12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, 8 parts of the root of Chinese clematis, wood
30 parts of melon, 10 parts of corydalis tuber, 8 parts of Rhizoma Chuanxiong.
The preparation method of invention formulation, key technology are:
1) by 12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, the root of Chinese clematis 8
Part, 30 parts of pawpaw, 10 parts of corydalis tuber, 8 parts of Rhizoma Chuanxiong plus 7 times of amount water are decocted and are extracted 2 times, 2 hours every time, filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of temperature 70 C, vacuum degree 0.1Mpa；
3) by extract dry, it is ground into fine powder, is prepared into pill with the method in pharmaceutical technology.
Embodiment 5:
Invention formulation is made using following raw material:
15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, 12 parts of the root of Chinese clematis, wood
20 parts of melon, 15 parts of corydalis tuber, 3 parts of Rhizoma Chuanxiong.
The preparation method of invention formulation, key technology are:
1) by 15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, the root of Chinese clematis 12
Part, 20 parts of pawpaw, 15 parts of corydalis tuber, 3 parts of Rhizoma Chuanxiong plus 6 times of amount water are decocted and are extracted 3 times, 1 hour every time, filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.25 under the conditions of 80 DEG C of temperature, vacuum degree 0.08Mpa；
3) by extract dry, it is ground into fine powder, is prepared into oral solution with the method in pharmaceutical technology.
Embodiment 6:
Invention formulation is made using following raw material:
13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, 10 parts of the root of Chinese clematis, wood
25 parts of melon, 12 parts of corydalis tuber, 5 parts of Rhizoma Chuanxiong.
The preparation method of invention formulation, key technology are:
1) by 13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, the root of Chinese clematis 10
Part, 25 parts of pawpaw, 12 parts of corydalis tuber, 5 parts of Rhizoma Chuanxiong plus 1.5 times of amount water are decocted and are extracted 5 times, and 1.5 hours every time, filtering merged filter
Liquid；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of 75 DEG C of temperature, vacuum degree 0.09Mpa；
3) medicinal extract is put into 300 parts of brewing grains white spirits and stirs evenly, is still aging, filtering, bottles up to wine liquid.
Embodiment 7:
Invention formulation is made using following raw material:
12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, 8 parts of the root of Chinese clematis, wood
30 parts of melon, 10 parts of corydalis tuber, 8 parts of Rhizoma Chuanxiong, 5 parts of herba taxilli.
The preparation method of invention formulation, key technology are:
1) by 12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, the root of Chinese clematis 8
Part, 30 parts of pawpaw, 10 parts of corydalis tuber, 8 parts of Rhizoma Chuanxiong, 5 parts of herba taxilli plus 7 times of amount water are decocted and are extracted 2 times, 2 hours every time, filter,
Merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of temperature 70 C, vacuum degree 0.1Mpa；
3) by extract dry, it is ground into fine powder, is prepared into particle with the method in pharmaceutical technology.
Embodiment 8:
Invention formulation is made using following raw material:
15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, 12 parts of the root of Chinese clematis, wood
20 parts of melon, 15 parts of corydalis tuber, 3 parts of Rhizoma Chuanxiong, 15 parts of herba taxilli.
The preparation method of invention formulation, key technology are:
1) by 15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, the root of Chinese clematis 12
Part, 20 parts of pawpaw, 15 parts of corydalis tuber, 3 parts of Rhizoma Chuanxiong, 15 parts of herba taxilli plus 8 times of amount water, decoction extraction 3 times, 1 hour every time, mistake
Filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.25 under the conditions of 80 DEG C of temperature, vacuum degree 0.08Mpa；
3) by extract dry, it is ground into fine powder, is prepared into capsule with the method in pharmaceutical technology.
Embodiment 9:
Invention formulation is made using following raw material:
13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, 10 parts of the root of Chinese clematis, wood
25 parts of melon, 12 parts of corydalis tuber, 5 parts of Rhizoma Chuanxiong, 10 parts of herba taxilli.
The preparation method of invention formulation, key technology are:
1) by 13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, the root of Chinese clematis 10
Part, 25 parts of pawpaw, 12 parts of corydalis tuber, 5 parts of Rhizoma Chuanxiong, 10 parts of herba taxilli plus 7 times of amount water, decoction extraction 2 times, 1.5 hours every time, mistake
Filter, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of 75 DEG C of temperature, vacuum degree 0.09Mpa；
3) medicinal extract is put into 400 parts of brewing grains white spirits and stirs evenly, is still aging, filtering, bottles up to wine liquid.
Embodiment 10:
Invention formulation is made using following raw material:
12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, 8 parts of the root of Chinese clematis, wood
30 parts of melon, 10 parts of corydalis tuber, 8 parts of Rhizoma Chuanxiong, 5 parts of herba taxilli, 5 parts of pangolin (processing).
The preparation method of invention formulation, key technology are:
1) by 12 parts of berba aristolochiae mollissimae, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of safflower, 25 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae, 18 parts of radix scrophulariae, the root of Chinese clematis 8
Part, 30 parts of pawpaw, 10 parts of corydalis tuber, 8 parts of Rhizoma Chuanxiong, 5 parts of herba taxilli, 5 parts of pangolin (processing) plus 6 times of amount water decoct and extract 2
It is secondary, 2 hours every time, filtering, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of temperature 70 C, vacuum degree 0.1Mpa；
3) by extract dry, it is ground into fine powder, is prepared into particle with the method in pharmaceutical technology.
Embodiment 11:
Invention formulation is made using following raw material:
15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, 12 parts of the root of Chinese clematis, wood
20 parts of melon, 15 parts of corydalis tuber, 3 parts of Rhizoma Chuanxiong, 15 parts of herba taxilli, 3 parts of pangolin (processing).
The preparation method of invention formulation, key technology are:
1) by 15 parts of berba aristolochiae mollissimae, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of safflower, 15 parts of Cortex Eucommiae, 25 parts of radix achyranthis bidentatae, 12 parts of radix scrophulariae, the root of Chinese clematis 12
Part, 20 parts of pawpaw, 15 parts of corydalis tuber, 3 parts of Rhizoma Chuanxiong, 15 parts of herba taxilli, 3 parts of pangolin (processing) plus 8 times of amount water decoct and extract 3
It is secondary, 1 hour every time, filtering, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.25 under the conditions of 80 DEG C of temperature, vacuum degree 0.08Mpa；
3) by extract dry, it is ground into fine powder, is prepared into capsule with the method in pharmaceutical technology.
Embodiment 12:
Invention formulation is made using following raw material:
13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, 10 parts of the root of Chinese clematis, wood
25 parts of melon, 12 parts of corydalis tuber, 5 parts of Rhizoma Chuanxiong, 10 parts of herba taxilli, 4 parts of pangolin (processing).
The preparation method of invention formulation, key technology are:
1) by 13 parts of berba aristolochiae mollissimae, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of safflower, 20 parts of Cortex Eucommiae, 22 parts of radix achyranthis bidentatae, 16 parts of radix scrophulariae, the root of Chinese clematis 10
Part, 25 parts of pawpaw, 12 parts of corydalis tuber, 5 parts of Rhizoma Chuanxiong, 10 parts of herba taxilli, 4 parts of pangolin (processing) plus 7 times of amount water decoct and extract 2
It is secondary, 1.5 hours every time, filtering, merging filtrate；
2) filtrate is concentrated into the medicinal extract of relative density 1.20 under the conditions of 75 DEG C of temperature, vacuum degree 0.09Mpa；
3) medicinal extract is put into 400 parts of brewing grains white spirits and stirs evenly, is still aging, filtering, bottles up to wine liquid.
Claims (8)
1. a kind of Chinese materia medica preparation for treating osteoproliferation, it is characterised in that the raw material for preparing its active constituent includes following parts by weight
Raw material:
Berba aristolochiae mollissimae 12~15, Radix Salviae Miltiorrhizae 15~30, safflower 10~15, Cortex Eucommiae 15~25, radix achyranthis bidentatae 20~25, radix scrophulariae 12~18, Wheeling
Celestial 8~12, pawpaw 20~30, corydalis tuber 10~15.
2. it is described in claim 1 treatment osteoproliferation Chinese materia medica preparation preparation method, it is characterised in that by berba aristolochiae mollissimae 12~
15 parts, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, 15~25 parts of Cortex Eucommiae, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, the root of Chinese clematis 8
~12 parts, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber add water to cook extraction, filter, filtrate is condensed into leaching by merging filtrate
Cream；By extract dry, it is prepared into particle, wine liquid, capsule, tablet, pill or oral solution.
3. treating the Chinese materia medica preparation of osteoproliferation described in claim 1, it is characterised in that the raw material for preparing its active constituent also wraps
Include 3~8 parts of Rhizoma Chuanxiong.
4. it is as claimed in claim 3 treatment osteoproliferation Chinese materia medica preparation preparation method, it is characterised in that by berba aristolochiae mollissimae 12~
15 parts, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, 15~25 parts of Cortex Eucommiae, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, the root of Chinese clematis 8
~12 parts, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber, 3~8 parts of Rhizoma Chuanxiong add water to cook extraction, filter, merging filtrate will filter
Liquid is condensed into medicinal extract；By extract dry, it is prepared into particle, wine liquid, capsule, tablet, pill or oral solution.
5. treating the Chinese materia medica preparation of osteoproliferation described in claim 3, it is characterised in that the raw material for preparing its active constituent also wraps
Include 5~15 parts of herba taxilli.
6. treating the preparation method of the Chinese materia medica preparation of osteoproliferation described in claim 5, it is characterised in that by berba aristolochiae mollissimae 12~15
Part, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, 15~25 parts of Cortex Eucommiae, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, the root of Chinese clematis 8~
12 parts, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber, 3~8 parts of Rhizoma Chuanxiong, 5~15 parts of herba taxilli add water to cook extraction, filter, close
And filtrate, filtrate is condensed into medicinal extract；By extract dry, it is prepared into particle, wine liquid, capsule, tablet, pill or oral solution.
7. treating the Chinese materia medica preparation of osteoproliferation described in claim 5, it is characterised in that the raw material for preparing its active constituent also wraps
Include 3~5 parts of pangolin.
8. treating the preparation method of the Chinese materia medica preparation of osteoproliferation described in claim 7, it is characterised in that by berba aristolochiae mollissimae 12~15
Part, 15~30 parts of Radix Salviae Miltiorrhizae, 10~15 parts of safflower, 15~25 parts of Cortex Eucommiae, 20~25 parts of radix achyranthis bidentatae, 12~18 parts of radix scrophulariae, the root of Chinese clematis 8~
12 parts, 20~30 parts of pawpaw, 10~15 parts of corydalis tuber, 3~8 parts of Rhizoma Chuanxiong, 5~15 parts of herba taxilli, 3~5 parts of pangolin plus decocting
Extraction is boiled, is filtered, filtrate is condensed into medicinal extract by merging filtrate；By extract dry, it is prepared into particle, wine liquid, capsule, tablet, ball
Agent or oral solution.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331983A (en) * | 2001-03-13 | 2002-01-23 | 曲丽萍 | Hyperosteogeny treating medicine |
-
2018
- 2018-10-23 CN CN201811237406.6A patent/CN108969594A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331983A (en) * | 2001-03-13 | 2002-01-23 | 曲丽萍 | Hyperosteogeny treating medicine |
Non-Patent Citations (3)
| Title |
|---|
| 常风云等: "牛膝治疗跟骨骨质增生", 《中医杂志》 * |
| 李贯彻: "骨增酒治疗骨质增生", 《四川中医》 * |
| 王朝阳: "中西医结合治疗腰椎间盘突出症", 《川北医学院学报》 * |
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Application publication date: 20181211 |