CN108949505B - 一种核酸提取装置及方法 - Google Patents
一种核酸提取装置及方法 Download PDFInfo
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- CN108949505B CN108949505B CN201810928509.0A CN201810928509A CN108949505B CN 108949505 B CN108949505 B CN 108949505B CN 201810928509 A CN201810928509 A CN 201810928509A CN 108949505 B CN108949505 B CN 108949505B
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- 238000000605 extraction Methods 0.000 title claims abstract description 124
- 150000007523 nucleic acids Chemical class 0.000 title claims description 47
- 102000039446 nucleic acids Human genes 0.000 title claims description 47
- 108020004707 nucleic acids Proteins 0.000 title claims description 47
- 238000000034 method Methods 0.000 title claims description 9
- 230000007246 mechanism Effects 0.000 claims abstract description 121
- 238000005070 sampling Methods 0.000 claims abstract description 43
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 29
- 238000005406 washing Methods 0.000 claims abstract description 28
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 13
- 239000000284 extract Substances 0.000 claims abstract description 4
- 230000001360 synchronised effect Effects 0.000 claims description 33
- 230000003373 anti-fouling effect Effects 0.000 claims description 26
- 230000000149 penetrating effect Effects 0.000 claims description 20
- 230000001954 sterilising effect Effects 0.000 claims description 14
- 238000002347 injection Methods 0.000 claims description 13
- 239000007924 injection Substances 0.000 claims description 13
- 239000011148 porous material Substances 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000002955 isolation Methods 0.000 description 12
- 238000011109 contamination Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000011324 bead Substances 0.000 description 2
- 230000002070 germicidal effect Effects 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
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- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
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- Crystallography & Structural Chemistry (AREA)
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Abstract
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Claims (9)
Priority Applications (1)
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CN201810928509.0A CN108949505B (zh) | 2018-08-15 | 2018-08-15 | 一种核酸提取装置及方法 |
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CN201810928509.0A CN108949505B (zh) | 2018-08-15 | 2018-08-15 | 一种核酸提取装置及方法 |
Publications (2)
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CN108949505A CN108949505A (zh) | 2018-12-07 |
CN108949505B true CN108949505B (zh) | 2024-04-02 |
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CN201810928509.0A Active CN108949505B (zh) | 2018-08-15 | 2018-08-15 | 一种核酸提取装置及方法 |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3940052A4 (en) * | 2019-03-12 | 2023-01-25 | Hui Chen | DEVICE FOR NUCLEIC ACID EXTRACTION |
CN110511865A (zh) * | 2019-08-29 | 2019-11-29 | 中国科学院苏州生物医学工程技术研究所 | 高通量核酸提取系统 |
CN113025467B (zh) * | 2021-04-15 | 2022-08-09 | 杭州安誉科技有限公司 | 一种核酸检测过程中脱氧核糖核酸提取装置 |
CN217628409U (zh) * | 2021-05-14 | 2022-10-21 | 台达电子工业股份有限公司 | 核酸萃取盘组合 |
WO2023041042A1 (zh) * | 2021-09-17 | 2023-03-23 | 圣湘生物科技股份有限公司 | 核酸提取检测设备及核酸提取检测方法 |
CN116410842A (zh) * | 2021-12-31 | 2023-07-11 | 博尔诚(北京)科技有限公司 | 一种全自动核酸甲基化处理设备和处理机构 |
CN114308172A (zh) * | 2022-03-03 | 2022-04-12 | 迈德(山东)科技股份有限公司 | 一种全自动试剂分装装置及分装方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06113814A (ja) * | 1992-10-05 | 1994-04-26 | Hitachi Ltd | 生化学装置 |
JP2014020779A (ja) * | 2012-07-12 | 2014-02-03 | Hitachi High-Technologies Corp | 核酸抽出装置 |
WO2015072941A1 (en) * | 2013-11-15 | 2015-05-21 | Anatolia Tani Ve Biyoteknoloji Urunleri Arastirma Gelistirme Sanayi Ve Ticaret Anonim Sirketi | Laboratory automation system |
WO2017024899A1 (zh) * | 2015-08-11 | 2017-02-16 | 广州康昕瑞基因健康科技有限公司 | 一种试剂工作站 |
CN108048302A (zh) * | 2018-02-01 | 2018-05-18 | 北京同立创辉仪器有限公司 | 全自动核酸提取仪 |
CN208898865U (zh) * | 2018-08-15 | 2019-05-24 | 烟台艾德康生物科技有限公司 | 一种核酸提取装置 |
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2018
- 2018-08-15 CN CN201810928509.0A patent/CN108949505B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06113814A (ja) * | 1992-10-05 | 1994-04-26 | Hitachi Ltd | 生化学装置 |
JP2014020779A (ja) * | 2012-07-12 | 2014-02-03 | Hitachi High-Technologies Corp | 核酸抽出装置 |
WO2015072941A1 (en) * | 2013-11-15 | 2015-05-21 | Anatolia Tani Ve Biyoteknoloji Urunleri Arastirma Gelistirme Sanayi Ve Ticaret Anonim Sirketi | Laboratory automation system |
WO2017024899A1 (zh) * | 2015-08-11 | 2017-02-16 | 广州康昕瑞基因健康科技有限公司 | 一种试剂工作站 |
CN108048302A (zh) * | 2018-02-01 | 2018-05-18 | 北京同立创辉仪器有限公司 | 全自动核酸提取仪 |
CN208898865U (zh) * | 2018-08-15 | 2019-05-24 | 烟台艾德康生物科技有限公司 | 一种核酸提取装置 |
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Inventor after: Zhang Lihai Inventor after: Cao Yiliang Inventor after: Dong Liying Inventor after: Shao Wei Inventor after: Zhang Meng Inventor after: Guo Xinfeng Inventor before: Zhang Lihai Inventor before: Cao Yiliang Inventor before: Shao Wei Inventor before: Zhang Meng Inventor before: Guo Xinfeng |
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