CN108938188A - Eye drops bottle - Google Patents
Eye drops bottle Download PDFInfo
- Publication number
- CN108938188A CN108938188A CN201810985492.2A CN201810985492A CN108938188A CN 108938188 A CN108938188 A CN 108938188A CN 201810985492 A CN201810985492 A CN 201810985492A CN 108938188 A CN108938188 A CN 108938188A
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- CN
- China
- Prior art keywords
- internal plug
- eye drops
- bottle body
- inner cover
- internal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
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- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of eye drops bottle.It is made of outer cover, inner cover, internal plug and bottle body.The inner cover lower edge is designed to plum blossom internal tooth, and top sets pressure sensitivity piston；The internal plug is the specially made structure of bottom film sealing processing, and bottom is designed to plum blossom external tooth, is mutually agreed with the plum blossom internal tooth of inner cover using sealing film sealing, internal plug external collar；The bottleneck lower inside of the bottle body is pierced equipped with built-in convex.Different drug units is placed in internal plug and bottle body respectively.Pass through the pressure sensitivity piston covered in pressing, internal plug is pushed to move down, the built-in convex of bottleneck is set to be pierced into the inner membrance of internal plug bottom, rotation inner cover drives internal plug to rotate simultaneously, internal plug bottom inner membrance is scratched, the drug unit I being placed in internal plug falls into bottle body, can be used after mixing with the drug unit II in bottle body.The present invention can mutually separate different pharmaceutical unit, instant molten, efficiently solve the eye drop formulation problem of poor stability in solution, light-exposed easy decomposition or the drugs such as oxidizable.
Description
Technical field
The invention is related to medicament packaging container field, and in particular to a kind of novel eye drop bottle.
Background technique
China's ophthalmology disease disease incidence is relatively high, and opthalmological utilization rate has reached 28%.With population growth and
The development of aging, China's ophthalmology disease disease incidence is in rising situation.Eye drops is the main dosage form of ophthalmic remedy, it has valence
Lattice are cheap, patient is easy to receive, is easy the advantages that preparing, so eye drops using very extensive, accounts about entire eye-drops preparations
70%.
Eye drops is meant made of material medicine and proper auxiliary materials for instilling intraocular sterile liquid formulations.Many institute's weeks
Know, the solution type preparation of chemicals is unstable compared with solid-state version preparation, this allows for some unstable drugs in aqueous solution
Eye drops can not be made.Due to the presence of blood-eye barrier, drug when Formulations for systemic administration is made to be difficult to reach effective concentration in eyeball, because
The active drug treatment of this most of eye disease is still local administration, i.e. eye drop administration.
Packaging is to improve an important ring for drug quality, and the stability of eye drops with prescription itself in addition to having outside the Pass, packaging
Influence of the material to it is also of crucial importance, and suitable packaging can make up difference caused by prescription.Although can will be water-soluble
In liquid unstable drug, oxidizable drug, light-exposed labile drug or compound preparation with powder, particle, bulk or
It is sheet form packaging, another standby solvent, matching while using when use, but drug must be contacted in operation, and when making up a prescription
Drug is contacted with air, and environment can pollute drug, to destroy the germ-free condition of eye drops, influences what drug used
Safety.
Summary of the invention
To solve the above-mentioned problems, it is an object of the present invention to a kind of novel eye drop bottles, by different medicines
Object unit mutually separates, instant molten, avoids chance water unstable drug in production and decomposes in storage, efficiently solves solution
The eye drop formulation problem of the drug of middle stability difference.
To achieve the above object, the invention provides following technical solution: eye drops bottle, by outer cover, inner cover,
Internal plug and bottle body are constituted.
The bottle body is made of body and bottleneck, is pierced in bottleneck inner lower edge equipped with built-in convex, in bottleneck inner sidewall
Lower part is equipped with locating slot and lower locating slot in annular setting up and down.
The internal plug is constituted by going out liquid portion and medicament lumen, is provided with liquid outlet on the top in liquid portion out, the bottom of medicament lumen is logical
Overstocked sealer closing, the lower end outer wall of medicament lumen are equipped with bulge loop；The medicament lumen of internal plug is placed in the bottleneck of bottle body, and by convex
Ring is moved in lower locating slot from upper locating slot drives internal plug to move down.
The inner cover is connect with internal plug, and will be gone out in liquid portion is wrapped in, and the top of inner cover is equipped with pressure sensitivity piston, pressure sensitivity piston
It is corresponding with liquid outlet, by pushing internal plug to move down by pressure sensitive piston.
The outer cover is connect with bottle body.
Further, above-mentioned eye drops bottle, the outer cover are the plastic lid with antitheft tooth.
Further, above-mentioned eye drops bottle, the inner cover lower edge inside are equipped with plum blossom internal tooth, the internal plug
The outer wall of liquid portion and medicament lumen junction is equipped with plum blossom external tooth out, and plum blossom internal tooth mutually agrees with plum blossom external tooth.
Further, above-mentioned eye drops bottle, the bottle body, internal plug, inner cover and outer cover material be PE (poly- second
Alkene), the one or more of PP (polypropylene) or PET (polyethylene terephthalate).
Further, above-mentioned eye drops bottle, the pressure sensitivity piston have the displacement of 0.5-2mm, preferably 1.0-
1.5mm。
Further, above-mentioned eye drops bottle, the material of the sealing film be PE, PP, PET or metal one kind or
It is several.
Further, the material of above-mentioned eye drops bottle, the built-in convex thorn is one kind of PE, PP, PET or metal
Or it is several.
Further, above-mentioned eye drops bottle, holding medicine unit I in medicament lumen；Holding medicine unit in bottle body
Ⅱ。
Further, above-mentioned eye drops bottle, drug unit I and drug unit II be pill, medicinal powder, tablet or
Liquid it is one or more.
Further, above-mentioned eye drops bottle, the pill, medicinal powder, tablet or liquid are active medicine, pH
It is worth one or more of combinations of regulator, isotonic regulator, bacteriostatic agent, viscosity modifier, antioxidant, chelating agent, stabilizer
Object.
The advantages of the invention, is: the invention, can be by the separately made particle of drug, the piece, ball of stability difference
Equal drug units are put into internal plug in industrialization process, and internal plug bottom is sealed with film, the drug unit I when storage in internal plug with
Drug unit II in bottle body separates, and stability is unaffected, instant molten, and it is poor, light-exposed to efficiently solve stability in solution
The easily eye drop formulation problem of decomposition or oxidizable equal drugs.
Detailed description of the invention
Fig. 1 is the decomposition state schematic diagram of the invention eye drop bottle.
Fig. 2 is the assembled state schematic diagram of the invention eye drop bottle.
Fig. 3 is the front view of the invention eye drop bottle inner cover.
Fig. 4 is the top view of the invention eye drop bottle inner cover.
Fig. 5 is the front view of the invention eye drop bottle internal plug.
Fig. 6 is the top view of the invention eye drop bottle internal plug.
Fig. 7 is the front view of the invention eye drop bottle bottle body.
Specific embodiment
To keep the purposes, technical schemes and advantages of the invention clearer, the present invention is created below in conjunction with attached drawing
It is affected described in further detail.
As depicted in figs. 1 and 2, eye drops bottle is made of outer cover 10, inner cover 20, internal plug 30 and bottle body 40.
1, outer cover 10
Outer cover 10 is the plastic lid with antitheft tooth.The material of outer cover 10 can be PE, PP or PET.
2, inner cover 20
As shown in Figure 3 and Figure 4, the top of inner cover 20 is equipped with pressure sensitivity piston 21, is equipped in plum blossom on the inside of 20 lower edge of inner cover
Tooth 22.The pressure sensitivity piston 21 has the displacement of 0.5-2mm, preferably 1.0-1.5mm.It is pushed by pressing down on pressure sensitivity piston 21
Internal plug 30 moves down.
The material of the inner cover 20 is PE, PP or PET.
3, internal plug 30
As shown in Figure 5 and Figure 6, the internal plug 30 is constituted by going out liquid portion 31 and 32 two parts of medicament lumen, in liquid portion 31 out
Top is provided with liquid outlet 33, and the bottom of medicament lumen 32 is closed by sealing film 34, and the lower end outer wall of medicament lumen 32 is equipped with a circle
Bulge loop 35.
Internal plug 30 go out 32 intersection of liquid portion 31 and medicament lumen outer wall on be equipped with plum blossom external tooth 36, plum blossom external tooth 36 with
22 phase of plum blossom internal tooth of inner cover 20 is agreed with.
The material of the internal plug 30 is PE, PP or PET.
The material of the sealing film 34 is PE, PP, PET or metal.
Holding medicine unit I 37 in medicament lumen 32.Drug unit I is one kind or more of pill, medicinal powder, tablet or liquid
Kind.Pill, medicinal powder, tablet or the liquid is by active medicine, pH adjusting agent, isotonic regulator, bacteriostatic agent, viscosity-adjusting agent
Agent, antioxidant, chelating agent, stabilizer one or more of compositions be made.Preferably, drug unit I is pill or medicinal powder
Or tablet.
4, bottle body 40
As shown in fig. 7, the bottle body 40 is made of body and bottleneck, it is equipped with built-in convex thorn 41 in bottleneck inner lower edge,
The middle and lower part of bottleneck inner sidewall is equipped with locating slot 42 and lower locating slot 43 in annular setting up and down.
The material of the bottle body 40 is PE, PP or PET.
The material of the built-in convex thorn 41 is PE, PP, PET or metal.
Holding medicine unit II 44 in bottle body 40.Drug unit II is one kind or more of pill, medicinal powder, tablet or liquid
Kind.Pill, medicinal powder, tablet or the liquid is by active medicine, pH adjusting agent, isotonic regulator, bacteriostatic agent, viscosity-adjusting agent
Agent, antioxidant, chelating agent, stabilizer one or more of compositions be made.Preferably, drug unit II is liquid.
The medicament lumen 32 of internal plug 30 is placed in the bottleneck of bottle body 40, and passes through bulge loop 35 from the downward locating slot of upper locating slot 42
43 mobile drive internal plug 30 moves down.The inner cover 20 and internal plug 30 mutually agree with company by plum blossom internal tooth 22 and plum blossom external tooth 36
It connects, liquid portion 31 out is wrapped in interior by inner cover 20.After the outer cover 10 is connected through a screw thread with bottle body 40, inner cover and internal plug are wrapped up
Inside.Pressure sensitivity piston 21 is corresponding with liquid outlet 33, by pushing internal plug 30 to move down by pressure sensitive piston 21.
The application method of the invention is:
1, the medicament lumen bottom of 30 lower end of internal plug is sealed using sealing film 34, and drug unit I 37 is placed in drug before sealing
It is intracavitary.Drug unit II 44 is placed in bottle body.Then the medicament lumen of internal plug is inserted into the bottleneck of bottle body, so that annular convex ring
35 are inserted into upper locating slot 42, and built-in convex thorn 41 has a certain distance with sealing film 34 at this time.Then 20 He of inner cover is successively covered
Outer cover 10.
Using the invention, drug unit I and drug unit II is respectively prepared in eye drip pharmaceutical composition, such as drug list
Member II is solution dosage, and drug unit I is made pill, tablet or powder, stores respectively, in use, matching while using.
2, for the first time in use, open outer cover, by the pressure sensitivity piston that covers in pressing, internal plug is pushed to move down, bulge loop 35 by
Upper locating slot 42 moves down into lower locating slot 43, and built-in convex thorn 41 is pierced into sealing film 34 at this time, and rotation inner cover drives internal plug to turn simultaneously
Dynamic, since bottle body is motionless, the sealing film of internal plug bottom is built convex thorn and scratches, and the drug unit I being placed in internal plug falls into bottle
Body is uniformly mixed drug unit I and drug unit II by rocking, inner cover is removed, by squeezing hybrid medicine by going out
Liquid mouth instills human eye.
The present invention can mutually separate different pharmaceutical unit, instant molten, and it is poor, light-exposed to efficiently solve stability in solution
The easily eye drop formulation problem of decomposition or oxidizable equal drugs.
Claims (10)
1. eye drops bottle, which is characterized in that be made of outer cover (10), inner cover (20), internal plug (30) and bottle body (40)；It is described
Bottle body (40) is made of body and bottleneck, built-in convex thorn (41) is equipped in bottleneck inner lower edge, in the middle and lower part of bottleneck inner sidewall
Equipped with locating slot (42) in annular setting up and down and lower locating slot (43)；The internal plug (30) is by going out liquid portion (31) and medicament lumen
(32) it constituting, is provided with liquid outlet (33) on the top of liquid portion (31) out, the bottom of medicament lumen (32) is closed by sealing film (34),
The lower end outer wall of medicament lumen (32) is equipped with bulge loop (35)；The medicament lumen (32) of internal plug (30) is placed in the bottleneck of bottle body (40),
And it is moved in lower locating slot (43) by bulge loop (35) from upper locating slot (42) and internal plug (30) is driven to move down；The inner cover (20)
It connect, and will go out in liquid portion (31) be wrapped in internal plug (30), the top of inner cover (20) is equipped with pressure sensitivity piston (21), pressure sensitivity piston
(21) corresponding with liquid outlet (33), by pushing internal plug (30) to move down by pressure sensitive piston (21)；The outer cover (10) with
Bottle body (40) connection.
2. eye drops bottle according to claim 1, which is characterized in that the outer cover (10) is with antitheft tooth
Plastic lid.
3. eye drops bottle according to claim 1, which is characterized in that be equipped with plum on the inside of inner cover (20) lower edge
The outer wall for going out liquid portion (31) and medicament lumen (32) junction of flower internal tooth (22), the internal plug (30) is equipped with plum blossom external tooth
(36), plum blossom internal tooth (22) mutually agrees with plum blossom external tooth (36).
4. eye drops bottle according to claim 1, which is characterized in that the bottle body (40), internal plug (30), inner cover
(20) and the material of outer cover (10) be PE, PP or PET one or more.
5. eye drops bottle according to claim 1, which is characterized in that the pressure sensitivity piston (21) has 0.5-2mm
Displacement, preferably 1.0-1.5mm.
6. eye drops bottle according to claim 1, which is characterized in that it is described sealing film (34) material be PE, PP,
The one or more of PET or metal.
7. eye drops bottle according to claim 1, which is characterized in that the material of built-in convex thorn (41) be PE,
The one or more of PP, PET or metal.
8. eye drops bottle according to claim 1, which is characterized in that the interior holding medicine unit I of medicament lumen (32)
(37)；The interior holding medicine unit II (44) of bottle body (40).
9. eye drops bottle according to claim 8, which is characterized in that drug unit I (37) and drug unit II
It (44) is the one or more of pill, medicinal powder, tablet or liquid.
10. eye drops bottle according to claim 9, which is characterized in that pill, medicinal powder, tablet or the liquid
For active medicine, pH adjusting agent, one kind of isotonic regulator, bacteriostatic agent, viscosity modifier, antioxidant, chelating agent, stabilizer
Or several composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810985492.2A CN108938188A (en) | 2018-08-28 | 2018-08-28 | Eye drops bottle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810985492.2A CN108938188A (en) | 2018-08-28 | 2018-08-28 | Eye drops bottle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108938188A true CN108938188A (en) | 2018-12-07 |
Family
ID=64474253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810985492.2A Pending CN108938188A (en) | 2018-08-28 | 2018-08-28 | Eye drops bottle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108938188A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007252759A (en) * | 2006-03-24 | 2007-10-04 | Shinko Chemical Co Ltd | Eye drop container |
| CN102006850A (en) * | 2008-04-17 | 2011-04-06 | 菲利普·佩罗维奇 | Device for storing, extemporaneously preparing, and administering |
| CN204341717U (en) * | 2014-11-30 | 2015-05-20 | 北京金鼐科技发展有限公司 | A kind of bottle cap with storage and release function |
| CN209301453U (en) * | 2018-08-28 | 2019-08-27 | 沈阳何氏眼产业集团有限公司 | Eye drops bottle |
-
2018
- 2018-08-28 CN CN201810985492.2A patent/CN108938188A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007252759A (en) * | 2006-03-24 | 2007-10-04 | Shinko Chemical Co Ltd | Eye drop container |
| CN102006850A (en) * | 2008-04-17 | 2011-04-06 | 菲利普·佩罗维奇 | Device for storing, extemporaneously preparing, and administering |
| CN204341717U (en) * | 2014-11-30 | 2015-05-20 | 北京金鼐科技发展有限公司 | A kind of bottle cap with storage and release function |
| CN209301453U (en) * | 2018-08-28 | 2019-08-27 | 沈阳何氏眼产业集团有限公司 | Eye drops bottle |
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| PB01 | Publication | ||
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