CN105997509A - Infusion container combination cover and infusion container capable of performing repeated direct preparation to multiple dosage forms - Google Patents
Infusion container combination cover and infusion container capable of performing repeated direct preparation to multiple dosage forms Download PDFInfo
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- CN105997509A CN105997509A CN201610563998.5A CN201610563998A CN105997509A CN 105997509 A CN105997509 A CN 105997509A CN 201610563998 A CN201610563998 A CN 201610563998A CN 105997509 A CN105997509 A CN 105997509A
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- nozzle
- prescription
- transfusion
- lid
- raised line
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- 238000001802 infusion Methods 0.000 title claims abstract description 68
- 239000002552 dosage form Substances 0.000 title abstract description 4
- 239000000843 powder Substances 0.000 claims abstract description 99
- 238000002347 injection Methods 0.000 claims abstract description 71
- 239000007924 injection Substances 0.000 claims abstract description 71
- 238000007789 sealing Methods 0.000 claims abstract description 27
- 239000003814 drug Substances 0.000 claims description 60
- 239000007788 liquid Substances 0.000 claims description 47
- 238000004804 winding Methods 0.000 claims description 24
- 238000003466 welding Methods 0.000 claims description 19
- 239000002131 composite material Substances 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 3
- 238000005192 partition Methods 0.000 abstract 1
- JGSARLDLIJGVTE-UHFFFAOYSA-N 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical compound O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-UHFFFAOYSA-N 0.000 description 23
- 238000000034 method Methods 0.000 description 10
- 239000003708 ampul Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000003640 drug residue Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 241001484259 Lacuna Species 0.000 description 1
- GQWNECFJGBQMBO-UHFFFAOYSA-N Molindone hydrochloride Chemical compound Cl.O=C1C=2C(CC)=C(C)NC=2CCC1CN1CCOCC1 GQWNECFJGBQMBO-UHFFFAOYSA-N 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000008393 encapsulating agent Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- -1 syringe Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/202—Separating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2058—Connecting means having multiple connecting ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses an infusion container capable of performing repeated direct preparation to multiple dosage forms. The infusion container comprises a container body (1) and a combination cover (2), wherein an interface (11) connected with the combination cover (2) is arranged in the container body (1); an opening end of a connecting nozzle (22) and the interface (11) of the container body (1) are sealed and welded; the combination cover (2) comprises a powder injection dispensing nozzle (21), a connecting nozzle (22), an infusion nozzle (23) and a puncture needle (24); the opening end of the powder injection dispensing nozzle (21) is further connected with a snap lid (25) which is in fusion-connected with the powder injection dispensing nozzle (21); and a first positioning structure and a second positioning structure which are matched with the partition plates of the puncture needle (24) are arranged on the inner wall of the powder injection dispensing nozzle (21). Medical staffs and disinfection supplies can be saved, the transparent consumption and transparent treatment can be realized, repeated dispensing can be realized, secondary pollution can be reduced, the safety can be enhanced, the infusion container is suitable for production of a production line, and the sealing property is good.
Description
Technical field
The present invention relates to a kind of medical supplies, a kind of Combined cap of transfusion container multi-pharmaceutics the most directly can joined and infusion vessel.
Background technology
nullAs Figure 1-5，When people's transfusion at present needs the injectable powder that use cillin bottle 3 is filled，It is usually and first uses syringe 4 from infusion vessel body 1(Fig. 1、Shown in 5 for infusion bottle，Certainly，Can also be transfusion bag) middle some liquid of extraction are (as shown in Figure 1，Liquid is generally normal saline、G/W etc.)，Then inject liquid into equipped with in the cillin bottle 3 of injectable powder (as shown in Figure 2，Powder pin bottle can also be)，Shake the injectable powder in equal cillin bottle 3 again，Make injectable powder medicine with the liquid mixing in cillin bottle 3 uniformly (as shown in Figure 3)，Medicinal liquid (the mixing liquid that injectable powder medicine is formed) is extracted out (as shown in Figure 4) with the liquid in cillin bottle 3 then through syringe 4，Finally the medicinal liquid in syringe 4 is injected in infusion vessel body 1，Human body thus can be carried out infusion (injection system of medicinal liquid automatic transport) by the medicinal liquid in infusion vessel body 1.It addition, the lyophilized injectable powder that cillin bottle 3 is filled or aqueous injection etc. be also substantially use above-mentioned first extract (directly extracting out or by extracting out after liquid mixing) medicine out, the method that reinjects infusion vessel body 1 carries out mixed medicine.Although then medicine and the liquid mixing in infusion vessel body 1 can be conveyed into human body, but use this dispensing method, there is problems in that by this mode
1. needing repeatedly to mix medicine, in general, from infusion vessel body 1, extraction liquid generally requires to medicine mixed in cillin bottle 3 and is repeated several times by just can being mixed in infusion vessel body 1 by whole injectable powder.
First, above-mentioned mixed medicine operating process is relatively time-consuming, laborious, take consumptive material, such as syringe, ethanol, absorbent cotton etc..
3. there is potential safety hazard.During above-mentioned mixed medicine, whole medicinal liquid does not completes under a closed environment, it is very easy to be injected in cillin bottle 3 and infusion vessel body 1 air of outside, much air exists under generic condition more various dust, pathogenic bacteria, enter back into human body after being mixed into liquid medicine injection, the most serious malpractice can be brought.
4. repeatedly interted by syringe needle on infusion vessel body 1 interface, during mixed medicine and transfusion, all there may exist leakage, the risk infected.
Currently also there is the structure of making up a prescription being provided with mixed medicine glass in transfusion bag, such as please CN 105232329 A(patent name in Chinese patent: medicine mixer, hard double nip and transfusion flexible bag), but it is primarily present following problem.
1. after cillin bottle 3 card gets on, being stuck, can not take, it is impossible to allocate the medicine of more than the second again in infusion vessel body 1 into, needing to inject (infusion) two or more medicine for prescription can not use simultaneously.
2. diaphragm seal seals mixed medicine glass so that the sealing structure non insurance of mixed medicine glass, whether has been truly realized real sealing without detection diaphragm seal with mixed medicine glass at present, there is serious potential safety hazard.
3. can only carry out a kind of dosage form to make up a prescription, it is difficult to carry out injectable powder and the multiple dosage form of aqueous injection is made up a prescription.
Sealing uses easily tore film, and at present the whole world welding PP material and film, there is no reliable detection equipment, it is impossible to ensure the encapsulant of 100% in expiration date of drug.
In addition to above-mentioned interpolation injectable powder medicine is infused, sometimes also need to add aqueous injection medicine is infused.When at present aqueous injection medicine (the liquid liquid medicine that ampoule bottle is contained) is carried out transfusion injection, the most directly extract, with syringe, the liquid liquid medicine that ampoule bottle is contained out, mouth identical with powder for injecta entrance in infusion vessel injects in infusion vessel, so can there is leakage, need the problems such as sterilization, and also liquid medicine can not be added at any time in midway, can only i.e. there is the deficiencies such as limited, dangerous, trouble in front injection of first infusing.
Summary of the invention
It is an object of the invention to overcome the above-mentioned deficiency of prior art to provide a kind of Combined cap of transfusion container can the most directly joined multi-pharmaceutics and infusion vessel, it can be saved medical worker, save a large amount of sterilizing article, realization " transparent consumption " and " understand treatment ", realizes multi-pharmaceutics and repeatedly make up a prescription, reduce secondary pollution and improve and use the safety of medicine personnel, can be suitable for pharmaceutical factory production line production, can ensure the medicine sealing in effect duration.
The technical scheme is that a kind of Combined cap of transfusion container can the most directly joined multi-pharmaceutics, it includes that make up a prescription nozzle, aqueous injection of lid, injectable powder makes up a prescription nozzle and transfusion nozzle；Lid is cup-shaped, and the injectable powder nozzle that makes up a prescription is connected with the cup-shaped bottom of lid, and the cup-shaped bottom of lid is provided with every liquid sheet；The make up a prescription other end of nozzle and lid of injectable powder is respectively opening；The make up a prescription inner chamber of nozzle of injectable powder is injectable powder dispensing cavity, and the inner chamber of lid is medicine liquid channel；Injectable powder make up a prescription nozzle opening on be also associated with powder pin easy-open lid, powder pin easy-open lid and injectable powder make up a prescription nozzle phase welding；The aqueous injection nozzle that makes up a prescription is tubulose, and it is located at lid one side；Transfusion nozzle is tubulose, and transfusion nozzle is located at another side of lid.
The further technical scheme of the present invention is: it also includes puncture needle, puncture needle be arranged on injectable powder make up a prescription nozzle dispensing cavity in；Puncture needle includes needle tubing and demarcation strip；Needle tubing includes winding the needle tube and lower needle tubing；Winding the needle tube is connected with lower needle tubing, and its interior medicament channel is connected；Demarcation strip is plate shape, and it is arranged on winding the needle tube and lower needle tubing connection.
The present invention further technical scheme is: described demarcation strip is provided with more than one clean-out opening；The head of winding the needle tube is pointed puncturing head, and the top of puncturing head is real core, described puncturing head usually cone；The side of winding the needle tube is provided with more than one ditch through hole at puncturing head；Its winding the needle tube is provided with protection set；Winding the needle tube, lower needle tubing and demarcation strip use and are disposably an integrally-molded.
The present invention further technical scheme is: described powder pin easy-open lid is provided with the easy handle of powder pin, and handle is strip or ring-type pull handle arrangement；The make up a prescription cup-shaped bottom of nozzle of injectable powder is equipped with pad, and pad is rubber cushion；It is integral type structure every liquid sheet and lid；Make up a prescription nozzle, aqueous injection of lid, injectable powder makes up a prescription nozzle and transfusion nozzle is the structure that integral type is molded.
The most further technical scheme of the present invention is: the described injectable powder nozzle inwall that makes up a prescription is provided with the first location structure that the demarcation strip with puncture needle matches, first location structure includes raised line and first time raised line on first, forming draw-in groove on first between raised line and first time raised line, raised line on first is or/and first time raised line is to be laid in annular raised line or the scattered multiple projection continuously that injectable powder makes up a prescription on nozzle inwall.
The further technical scheme of the present invention is: the described injectable powder nozzle inwall that makes up a prescription is additionally provided with the second location structure near the position of intermediate washer, second location structure includes end raised line, the make up a prescription bottom of nozzle of end raised line and injectable powder is spaced a distance, and distance size adapts with the thickness of demarcation strip；End raised line is to be laid in annular raised line or the scattered multiple projection continuously that injectable powder makes up a prescription on nozzle inwall.
The further technical scheme of the present invention is: raised line on first is or/and the internal diameter of first time raised line is less than demarcation strip external diameter；The internal diameter of end raised line is less than demarcation strip external diameter.
The further technical scheme of the present invention is: aqueous injection makes up a prescription nozzle inner chamber and lid intracavity inter-connection；Aqueous injection makes up a prescription the axis of nozzle with the horizontal the angle α of 15 ± 5 degree, i.e. α=15 ± 5 °；Aqueous injection make up a prescription nozzle free end on be additionally provided with aqueous injection easy-open lid, aqueous injection easy-open lid is a kind of easy-open lid, aqueous injection easy-open lid and aqueous injection make up a prescription the free end phase welding of nozzle, and aqueous injection easy-open lid outer end is provided with aqueous injection draw ring, is additionally provided with sealing gasket A and inner cap A in aqueous injection easy-open lid.
The further technical scheme of the present invention is: transfusion nozzle is used for being connected with infusion needle, the inner chamber of transfusion nozzle and lid intracavity inter-connection；The axis of transfusion nozzle is with the horizontal the angle β of 30 ± 5 degree, i.e. β=30 ± 5 °；Being additionally provided with transfusion easy-open lid on the free end of transfusion nozzle, the easy-open lid free end phase welding with transfusion nozzle of infusing, transfusion easy-open lid is provided with transfusion draw ring, is additionally provided with sealing gasket B and inner cap B in transfusion easy-open lid.
The present invention another solution is that a kind of infusion vessel can the most directly joined multi-pharmaceutics, and it includes container body and composite cover；Container body is transfusion bag or infusion bottle, and it is used for containing medicinal liquid, and container body is provided with interface, for being connected with composite cover；The opening of lid seals welding mutually with the interface of container body.
The present invention compared with prior art has a characteristic that
1. the present invention is truly realized flow of infusate and directly joins, once make up a prescription from existing one within about 3 minutes, be reduced to 20 seconds within；Directly join formula to mix medicine and decrease medical personnel's workload 60%, save medical worker, such as, the hospital of original 30 nurses of needs, may decrease to about 10 people.
2. can save a large amount of sterilizing article, save the resource of preciousness, reduced cost of curing the disease.Such as it is no longer necessary to the disposable syringe using ethanol, cotton swab infusion vessel to be carried out disinfection and makes up a prescription.
3. patient is it will be clear that oneself have input any medicine, not only realizes " transparent consumption ", it is often more important that what medicine patient it is known that oneself employ and treated actually.
4. can realize repeatedly making up a prescription, and an other medicine can be increased in the difference transfusion stage as required.Prior art uses folder bottle cover, powder pin bottle can only once make up a prescription certain limitation, and the present invention is by the clamping pressing from both sides bottle cover and change into carrying out puncture needle upper and lower two positions, i.e. puncture needle is respectively at two different settling positions before and after puncturing, both will not tamper, it is also possible to promote as required；Without by stuck for powder pin bottle (cillin bottle) after puncture, convenient after making up a prescription, powder pin bottle is taken off, be used for joining next powder pin bottle medicine, fundamentally solve and can only fundamentally be solved, by once making up a prescription as the problem repeatedly made up a prescription, the quality and speed made up a prescription.
The most whole process of making up a prescription is under sealing, aseptic state and carries out, and reduces the secondary pollution of medical personnel's operating process；Improve medical safety；Stop the sensitization etc. that medical personnel cause because of contact medicinal liquid when making up a prescription simultaneously, improve the safety using medicine personnel.
6. existing product is only suitable for pharmaceutical factory hard double nip production line, and by a definite limitation, and product of the present invention can be suitable for pharmaceutical factory single, double interface soft bag, plastic bottle infusion production line.
The most existing cup sealing of making up a prescription uses easily tore film, the at present whole world welding PP material and film, there is no reliable detection equipment, the sealing of 100% in expiration date of drug cannot be ensured, therefore use film material does sealing, there is certain sealing propertytest lacuna risk, and easy-open lid of the present invention welding (welding) mode, use material and the production technology of maturation that the nozzle that makes up a prescription with injectable powder is identical, this sealing means may insure that the memory cycle of medicine, fundamentally ensure that the medicine sealing in effect duration.
8. multi-pharmaceutics the most directly can be joined, say, that the powder medicine administered by injection thing in more than one cillin bottle can be formulated in infusion bottle, the aqueous injection medicine in more than one ampoule bottle is formulated in infusion bottle before transfusion；According to the needs for the treatment of, the powder medicine administered by injection thing in more than one cillin bottle can also be formulated in infusion bottle, the aqueous injection medicine in more than one ampoule bottle is formulated in infusion bottle in infusion process.
Below in conjunction with the drawings and specific embodiments, the detailed construction of the present invention is further described.
Accompanying drawing explanation
Infusion vessel and the structural representation of syringe when Fig. 1 is to extract liquid in existing infusion mode from infusion vessel (infusion bottle)；
Fig. 2 is to extract cillin bottle and the structural representation of syringe when liquid injects cillin bottle in existing infusion model from infusion vessel (infusion bottle)；
Fig. 3 is the structural representation in existing infusion mode equipped with medicine Yu the cillin bottle of the mixture of liquid；
Fig. 4 is the structural representation in existing infusion mode from cillin bottle extraction medicine with cillin bottle during the mixture of liquid with syringe；
Infusion vessel and the structural representation of syringe when Fig. 5 is, in existing infusion mode, the mixture of the medicine in syringe with liquid is injected infusion vessel；
Fig. 6 is the structural representation of the composite cover of the present invention；
Fig. 7 is that Fig. 6 is along the partial enlarged drawing in the range of A line；
Fig. 8 is that make up a prescription nozzle, aqueous injection of the injectable powder of the present invention makes up a prescription nozzle, connection mouth and transfusion nozzle structural representation；
Fig. 9 is the structural representation of the protection set of the puncture needle of the present invention；
Figure 10 is the structural representation of the puncture needle of the present invention；
Figure 11 is the structural representation of the infusion vessel of the present invention；
Figure 12 is the infusion vessel of present invention structural representation when preparing injectable powder (when cillin bottle is plugged)；
Figure 13 is that Figure 12 is along the partial enlarged drawing in the range of B line；
Figure 14 is the structural representation during infusion vessel use state of the present invention.
Detailed description of the invention
Embodiment 1
As shown in figs. 6-13: a kind of infusion vessel can the most directly joined multi-pharmaceutics, it includes container body 1 and composite cover 2；Container body 1 is transfusion bag or infusion bottle, as shown in Figure 11,12,14 for infusion bottle, it is used for containing medicinal liquid, and container body 1 is provided with interface 11(namely container body nozzle), for being connected with composite cover 2, the bore of the interface 11 on container body 1 is usually φ 28mm, φ 30mm, φ 32mm.
As illustrated in figures 6-10, composite cover 2 includes that make up a prescription nozzle 22, aqueous injection of lid 21, injectable powder makes up a prescription nozzle 23, transfusion nozzle 24 and puncture needle 25；Lid 21 is cup-shaped, the injectable powder nozzle 22 that makes up a prescription is connected with the cup-shaped bottom of lid 21, injectable powder makes up a prescription the cup-shaped bottom of nozzle 22 equipped with pad 221, pad 221 is rubber cushion, the cup-shaped bottom of lid 21 is provided with every liquid sheet 211, it is integral type structure every liquid sheet 211 and lid 21, ratio is relatively thin, barrier film can also be, to facilitate puncture, pad 221 and injectable powder made up a prescription nozzle 22 and lid 21 is isolated every liquid sheet 211, to ensure the medicinal liquid (medicinal liquid in container body 1 communicated before puncture with lid 21, such as Figure 11, 12, shown in 14) can be isolated with the injectable powder nozzle 22 that makes up a prescription, form sealing effectiveness；The make up a prescription other end of nozzle 22 and lid 21 of injectable powder is respectively opening；The make up a prescription inner chamber of nozzle 22 of injectable powder is injectable powder dispensing cavity, and the inner chamber of lid 21 is medicine liquid channel.
The opening of lid 21 seals welding (i.e. welding mode is connected, and reaches seal degree) with interface 11 phase of container body 1.
As shown in Figure 10, puncture needle 25 includes needle tubing and demarcation strip 253；Needle tubing includes winding the needle tube 251 and lower needle tubing 252；Winding the needle tube 251 is connected with lower needle tubing 252, and its interior medicament channel is connected (the most whole composition hollow tubular)；Demarcation strip 253 is plate shape, and it is arranged on winding the needle tube 251 and lower needle tubing 252 connection；Demarcation strip 253 is provided with more than one clean-out opening 2531, is usually and is circumferentially equipped with two to four clean-out openings 2531 on described demarcation strip 253；The head of winding the needle tube 251 is pointed puncturing head 2511, and the top of puncturing head 2511 is real core, described puncturing head 2511 usually cone；The side of winding the needle tube 251 is provided with more than one ditch through hole 2512, ditch through hole 2512 generally two to four at puncturing head 2511；Winding the needle tube 251 is or/and lower needle tubing 252 inwall is circumferentially equipped with two to four reinforcements.Winding the needle tube 251, lower needle tubing 252 and demarcation strip 253 generally use and are disposably an integrally-molded.
Puncture needle 25 be arranged on injectable powder make up a prescription nozzle 22 dispensing cavity in, its winding the needle tube 251 is provided with protection set 254, and protection set 254 can prevent winding the needle tube 251 from deforming and affecting puncture, it is also possible to prevents the head of winding the needle tube 251 from polluting；nullInjectable powder nozzle 22 inwall that makes up a prescription is provided with the first location structure that the demarcation strip with puncture needle 25 matches，As shown in Figure 7，First location structure includes raised line 222 and first time raised line 223 on first，Draw-in groove 224 is formed between raised line 222 and first time raised line 223 on first，Certainly，Raised line 222 on first is or/and first time raised line 223 can be to be laid in the annular raised line continuously that injectable powder makes up a prescription on nozzle 22 inwall，Can also be discontinuous (scattered multiple projections the most circumferentially，Belong to same design，Belong to the scope of protection of the invention)，Raised line 222 on first is or/and the height of first time raised line 223 projection can (medical worker presses slightly inwards with hands) pass through under a certain pressure with the demarcation strip 253 of puncture needle 25，On typically first, raised line 222 is or/and the internal diameter of first time raised line 223 more slightly smaller than demarcation strip external diameter (1-3 millimeter) ensures that this ferrule structure，Make demarcation strip 253 can be stuck in the first location structure (on first draw-in groove 224 in) between raised line 222 and first time raised line 223，Puncture needle 25 would not (Fig. 6 vertically、11、The above-below direction of 12) mobile (namely play up and down)，During use，Also people will not be stoped to pressing to pad 221 by puncture needle 25，Puncture needle 25 is only positioned by the i.e. first location structure，Rather than locked puncture needle 25.
As shown in figs. 12-14, injectable powder nozzle 22 inwall that makes up a prescription is additionally provided with the second location structure near the position of intermediate washer 221, second location structure includes end raised line 225, the make up a prescription bottom of nozzle 22 of end raised line 225 and injectable powder is spaced a distance, the thickness of distance size and demarcation strip 253 adapts, so end raised line 225 and injectable powder make up a prescription nozzle 22 bottom between also form one notch；After realizing puncturing, demarcation strip 253 moves and is stuck in end raised line 225 to the make up a prescription bottom of nozzle 22 of injectable powder, so puncture needle 25 would not slip out, ensure that the cillin bottle 3 of coupled handstand will not slip out (as shown in figure 14) during transfusion, i.e. the internal diameter of end raised line 225 more slightly smaller than demarcation strip external diameter (1-3 millimeter)；Demarcation strip 253 slightly firmly just can be pressed into inside end raised line 225 and (i.e. cross end raised line 225) by the height medical worker to be ensured of end raised line 225 projection, and ensures that cillin bottle will not drop out together with puncture needle 25 during transfusion；End raised line 225 is to be laid in annular raised line or the scattered multiple projection continuously that injectable powder makes up a prescription on nozzle 22 inwall.
First location structure and the second location structure are substantially to build a kind of clamping structure at injectable powder nozzle 22 inwall that makes up a prescription, and it can block puncture needle 25, not allow it tamper up and down, and it can also promote the structure of (medical worker somewhat exerts oneself) to puncture needle 25.
Injectable powder make up a prescription nozzle 22 opening on be also associated with powder pin easy-open lid 226, powder pin easy-open lid 226 is a kind of easy-open lid, powder pin easy-open lid 226 is provided with powder pin easy handle 2261(and includes strip, the pull handle arrangement such as ring-type), powder pin easy-open lid 226 nozzle 22 that makes up a prescription with injectable powder is connected by welding, realize sealing, so can improve sealing effectiveness, and conveniently carry out sealing detection, more far better than sealing the make up a prescription opening effect of nozzle 22 of injectable powder by diaphragm seal, this is also overcomed people and takes for for a long time just being sealed very well by diaphragm seal (reaching dust-proof, fungi-proofing, air-prevention passes through) injectable powder makes up a prescription the technology prejudice of nozzle 2 upper open end.
Make up a prescription nozzle 23 of aqueous injection is for tubulose, and it is located at lid 21 1 side, and it is for preparing (injection) aqueous injection medicine (ampoule bottle institute powder charge thing) in container body 1, and aqueous injection makes up a prescription nozzle 23 inner chamber and lid 21 intracavity inter-connection；Aqueous injection makes up a prescription the axis of nozzle 23 with the horizontal the angle α of 15 ± 5 degree, i.e. α=15 ± 5 °, usually 15 degree, i.e. aqueous injection makes up a prescription nozzle 23 in the side being inclined and mounted on lid 21 of about 15 degree, when being the most i.e. conducive to making up a prescription, medicinal liquid enters container body 1, it is also beneficial to totallyer defeated for medicinal liquid when transfusion, reduces drug residue (as shown in figure 14)；Aqueous injection make up a prescription nozzle 23 free end on be additionally provided with aqueous injection easy-open lid 231, aqueous injection easy-open lid 231 is a kind of easy-open lid, aqueous injection easy-open lid 231 makes up a prescription with aqueous injection free end phase welding (namely welding) of nozzle 23, aqueous injection easy-open lid 231 outer end is provided with aqueous injection draw ring 2311, can be by the easy-to-draw parts apart of aqueous injection easy-open lid 231 by draw ring, to open aqueous injection easy-open lid 231, sealing gasket A232 and inner cap A233 it is additionally provided with in aqueous injection easy-open lid 231, during use, aqueous injection draw ring 2311 is pulled open, the syringe needle of syringe inserts from sealing gasket A232, through inner cap A233, by in aqueous injection infusion of medicine container body 1.
Transfusion nozzle 24 is tubulose, and transfusion nozzle 24 is located at another side of lid 21, and it is for being connected with infusion needle, the inner chamber of transfusion nozzle 24 and lid 21 intracavity inter-connection；The axis of transfusion nozzle 24 is with the horizontal the angle β of 30 ± 5 degree, i.e. β=30 ± 5 °, usually 30 degree, i.e. transfusion nozzle 24 is in the side being inclined and mounted on lid 21 of about 30 degree, so be conducive to, by totallyer defeated for medicinal liquid, reducing drug residue (as shown in figure 14)；Transfusion easy-open lid 241 it is additionally provided with on the free end of transfusion nozzle 24, infuse easy-open lid 241 and free end phase welding (namely welding) of nozzle 24 of infusing, transfusion easy-open lid 241 is provided with transfusion draw ring 2411, the top board of transfusion easy-open lid 241 can be pulled open by transfusion draw ring 2411, it is additionally provided with sealing gasket B242 and inner cap B243 in transfusion easy-open lid 241, during use, transfusion draw ring 2411 is pulled open, infusion needle inserts from sealing gasket B242, through the top of inner cap B243, the whole infusion vessel that then stands upside down gets final product (as shown in figure 14).
Make up a prescription nozzle 22, aqueous injection of lid 21, injectable powder makes up a prescription nozzle 23 and transfusion nozzle 24 general (generally) employing integral type is molded.
The using method of the present invention and operation principle:
With powder pin bottle (i.e. cillin bottle 3; the most together), ampoule bottle and infusion bottle (i.e. container body 1; the using method of the present invention is described: torn by powder pin easy-open lid 226 as a example by the most together); take off puncture needle 25 and protect set 254; cillin bottle 3 in intervention; down pressing cillin bottle 3, puncture needle 25 to lower bayonet socket position (i.e. demarcation strip 253 snaps at the second location structure, as shown in Figure 12)；Puncture needle 25 by through the pad (diaphragm seal) of powder pin bottle, injectable powder make up a prescription nozzle 22 cup-shaped bottom equipped with pad 221 and the cup-shaped bottom of lid 21 be provided with every liquid sheet 211, infusion bottle is connected by puncture needle 25 with powder pin bottle；Shaking for several times, allow mixed medicine evenly, the medicine mixed enters infusion bottle, completes once to make up a prescription；If needing the most defeated multi-medicament, then need to dial down the powder pin bottle prepared for the first time according to treatment, again join second bottle of injectable powder medicine according to aforesaid operations flow process, as the method can join many bottles of injectable powder medicines；The aqueous injection medicine prepared the most as required, syringe is used to be extracted out by the aqueous injection medicine in ampoule bottle, the aqueous injection easy-open lid 231 made up a prescription by aqueous injection on nozzle 23 again pulls open, and syringe needle passes sealing gasket A232 and inner cap A233, is injected in infusion bottle by aqueous injection medicine from aqueous injection makes up a prescription nozzle 23；Transfusion starts, easy-open lid 241 of infusing on transfusion nozzle 24 is pulled to be provided with transfusion draw ring 2411, open transfusion nozzle 24, infusion needle passes sealing gasket B242 and inner cap B243, again shake all, the multiple medicine that mixes enters transfusion bag, and reversal of the natural order of things treatment starts, and the axis of transfusion nozzle 24 can ensure noresidue liquid (as shown in figure 14) in infusion bottle with the horizontal the oblique angle of 30 ± 5 degree；Aqueous injection makes up a prescription the axis of nozzle 23 with the horizontal the angle α of 15 ± 5 degree, it is ensured that noresidue liquid in infusion bottle, is also convenient for during transfusion again making up a prescription.
The present invention is not limited to above-mentioned concrete structure, as long as have the lid 21 essentially identical with the present invention, injectable powder makes up a prescription nozzle 22, aqueous injection makes up a prescription nozzle 23, the composite cover 2 of the infusion vessel of transfusion nozzle 24 and puncture needle 25 or infusion vessel just fall within the scope and spirit of the invention.
Claims (10)
1. the Combined cap of transfusion container can the most directly joined multi-pharmaceutics, including lid (21)；It is characterized in that: it also includes that make up a prescription nozzle (22), aqueous injection of injectable powder makes up a prescription nozzle (23) and transfusion nozzle (24)；Lid (21) is cup-shaped, and the injectable powder nozzle (22) that makes up a prescription is connected with the cup-shaped bottom of lid (21), and the cup-shaped bottom of lid (21) is provided with every liquid sheet (211)；The make up a prescription other end of nozzle (22) and lid (21) of injectable powder is respectively opening；The make up a prescription inner chamber of nozzle (22) of injectable powder is injectable powder dispensing cavity, and the inner chamber of lid (21) is medicine liquid channel；Injectable powder make up a prescription nozzle (22) opening on be also associated with powder pin easy-open lid (226), powder pin easy-open lid (226) and injectable powder make up a prescription nozzle (22) phase welding；The aqueous injection nozzle (23) that makes up a prescription is tubulose, and it is located at lid (21) side；Transfusion nozzle (24) is tubulose, and transfusion nozzle (24) is located at lid (21) another side.
The Combined cap of transfusion container can the most directly joined multi-pharmaceutics the most according to claim 1, is characterized in that: its also include puncture needle (25), puncture needle (25) be arranged on injectable powder make up a prescription nozzle (22) dispensing cavity in；Puncture needle (25) includes needle tubing and demarcation strip (253)；Needle tubing includes winding the needle tube (251) and lower needle tubing (252)；Winding the needle tube (251) is connected with lower needle tubing (252), and its interior medicament channel is connected；Demarcation strip (253) is plate shape, and it is arranged on winding the needle tube (251) and lower needle tubing (252) connection.
The Combined cap of transfusion container can the most directly joined multi-pharmaceutics the most according to claim 2, is characterized in that: described demarcation strip (253) is provided with more than one clean-out opening (2531)；The head of winding the needle tube (251) is pointed puncturing head (2511), and the top of puncturing head (2511) is real core, described puncturing head (2511) usually cone；The side of winding the needle tube (251) is provided with more than one ditch through hole (2512) near puncturing head (2511) place；Its winding the needle tube (251) is provided with protection set (254)；Winding the needle tube (251), lower needle tubing (252) and demarcation strip (253) use and are disposably an integrally-molded.
4. according to Combined cap of transfusion container multi-pharmaceutics the most directly can joined described in claim 1 or 2 or 3, it is characterized in that: described powder pin easy-open lid (226) is provided with the easy handle of powder pin (2261), handle (2261) is strip or ring-type pull handle arrangement；The make up a prescription cup-shaped bottom of nozzle (22) of injectable powder is rubber cushion equipped with pad (221), pad (221)；It is integral type structure every liquid sheet (211) and lid (21)；Make up a prescription nozzle (22), aqueous injection of lid (21), injectable powder makes up a prescription nozzle (23) and transfusion nozzle (24) is the structure that integral type is molded.
5. according to Combined cap of transfusion container multi-pharmaceutics the most directly can joined described in Claims 2 or 3, it is characterized in that: described injectable powder nozzle (22) inwall that makes up a prescription is provided with the first location structure that the demarcation strip with puncture needle (25) matches, first location structure includes raised line on first (222) and first time raised line (223), draw-in groove (224) is formed between raised line (222) and first time raised line (223) on first, raised line (222) on first is or/and first time raised line (223) is to be laid in annular raised line or the scattered multiple projection continuously that injectable powder makes up a prescription on nozzle (22) inwall.
Combined cap of transfusion container multi-pharmaceutics the most directly can joined the most according to claim 5, it is characterized in that: described injectable powder nozzle (22) inwall that makes up a prescription is additionally provided with the second location structure near the position of intermediate washer (221), second location structure includes end raised line (225), the make up a prescription bottom of nozzle (22) of end raised line (225) and injectable powder is spaced a distance, and distance size adapts with the thickness of demarcation strip (253)；End raised line (225) is to be laid in annular raised line or the scattered multiple projection continuously that injectable powder makes up a prescription on nozzle (22) inwall.
The Combined cap of transfusion container can the most directly joined multi-pharmaceutics the most according to claim 6, is characterized in that: raised line (222) on described first is or/and the internal diameter of first time raised line (223) is less than demarcation strip (253) external diameter；The internal diameter of end raised line (225) is less than demarcation strip (253) external diameter.
The Combined cap of transfusion container can the most directly joined multi-pharmaceutics the most according to claim 7, is characterized in that: described aqueous injection makes up a prescription nozzle (23) inner chamber and lid (21) intracavity inter-connection；Aqueous injection makes up a prescription the axis of nozzle (23) with the horizontal the angle α of 15 ± 5 degree, i.e. α=15 ± 5 °；Aqueous injection make up a prescription nozzle (23) free end on be additionally provided with aqueous injection easy-open lid (231), aqueous injection easy-open lid (231) is a kind of easy-open lid, aqueous injection easy-open lid (231) and aqueous injection make up a prescription the free end phase welding of nozzle (23), aqueous injection easy-open lid (231) outer end is provided with aqueous injection draw ring (2311), is additionally provided with sealing gasket A (232) and inner cap A (233) in aqueous injection easy-open lid (231).
9. the Combined cap of transfusion container can the most directly joined multi-pharmaceutics, is characterized in that: described transfusion nozzle (24) is used for being connected with infusion needle, the inner chamber of transfusion nozzle (24) and lid (21) intracavity inter-connection；The axis of transfusion nozzle (24) is with the horizontal the angle β of 30 ± 5 degree, i.e. β=30 ± 5 °；Transfusion easy-open lid (241) it is additionally provided with on the free end of transfusion nozzle (24), infuse easy-open lid (241) and the free end phase welding of nozzle (24) of infusing, transfusion easy-open lid (241) is provided with transfusion draw ring (2411), is additionally provided with sealing gasket B (242) and inner cap B (243) in transfusion easy-open lid (241).
10. the infusion vessel can the most directly joined multi-pharmaceutics, it includes container body (1)；It is characterized in that: it also includes that composite cover (2), composite cover (2) are the Combined cap of transfusion container can the most directly joined multi-pharmaceutics described in claim 1 or 2 or 3；Container body (1) is transfusion bag or infusion bottle, and it is used for containing medicinal liquid, and container body (1) is provided with interface (11), for being connected with composite cover (2)；The opening of lid (21) seals welding mutually with the interface (11) of container body (1).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610563998.5A CN105997509A (en) | 2016-07-18 | 2016-07-18 | Infusion container combination cover and infusion container capable of performing repeated direct preparation to multiple dosage forms |
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| CN201610563998.5A CN105997509A (en) | 2016-07-18 | 2016-07-18 | Infusion container combination cover and infusion container capable of performing repeated direct preparation to multiple dosage forms |
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| CN201610563998.5A Pending CN105997509A (en) | 2016-07-18 | 2016-07-18 | Infusion container combination cover and infusion container capable of performing repeated direct preparation to multiple dosage forms |
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Application publication date: 20161012 |