CN108938080B - Flexible microwave ablation needle under ultrasonic endoscope - Google Patents

Flexible microwave ablation needle under ultrasonic endoscope Download PDF

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Publication number
CN108938080B
CN108938080B CN201810833418.9A CN201810833418A CN108938080B CN 108938080 B CN108938080 B CN 108938080B CN 201810833418 A CN201810833418 A CN 201810833418A CN 108938080 B CN108938080 B CN 108938080B
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China
Prior art keywords
handle
radio frequency
tube
frequency coaxial
inner tube
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CN201810833418.9A
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CN108938080A (en
Inventor
于春生
江荣华
杨小唤
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Canyon Medical Inc
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Canyon Medical Inc
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Priority to CN201810833418.9A priority Critical patent/CN108938080B/en
Publication of CN108938080A publication Critical patent/CN108938080A/en
Priority to PCT/CN2019/097425 priority patent/WO2020020205A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1869Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument interstitially inserted into the body, e.g. needles

Abstract

The invention relates to a flexible microwave ablation needle under an ultrasonic endoscope, which comprises a handle, a radio frequency coaxial connector and a microwave radiation antenna, wherein the radio frequency coaxial connector is arranged on the handle, the radio frequency coaxial connector is connected with the microwave radiation antenna through a radio frequency coaxial cable, a capillary tube and an inner tube are sequentially arranged on the periphery of the radio frequency coaxial cable, the radio frequency coaxial cable is arranged in the capillary tube, the capillary tube is arranged in the inner tube, the inner tube comprises a first end part and a second end part, the first end part extends to the microwave radiation antenna, the second end part is far away from the microwave radiation antenna, and the inner tube gradually tapers from the second end part to the first end part. The ablation needle can reach more lesion sites and has strong penetrability.

Description

Flexible microwave ablation needle under ultrasonic endoscope
Technical Field
The invention relates to a flexible microwave ablation needle for performing microwave ablation treatment on tumors and pathological tissues in an abdominal cavity, and relates to the field of medical equipment for microwave treatment.
Background
At present, the medical industry in China is developing rapidly, meanwhile, the product demand refinement degree is higher and higher, the microwave ablation is widely applied as a minimally invasive operation, and the microwave ablation is to utilize the thermal effect of microwave biological tissues to stop bleeding, coagulate, burn or diminish inflammation, detumescence, relieve pain, improve local tissue blood circulation and the like of pathological tissues, so as to achieve the effect of treating diseases. It has the advantages of small wound, quick effect, strong penetrating power and the like, and is accepted by more and more patients.
Most of the existing microwave ablation minimally invasive surgery adopts B ultrasonic or X-ray imaging equipment and the like to locate a focus, and then adopts an external ablation needle to directly puncture the focus through skin and achieve microwave ablation after reaching the focus. The minimally invasive microwave ablation is limited by external conditions such as physical conditions of a patient, lesion positions, the length of an ablation antenna and the like, and meanwhile, the safe and accurate reaching of the lesion positions cannot be completely ensured for a puncture needle tract. Along with the increasing maturity of microwave ablation technology, the demand of microwave ablation needle is also more and more refined, and a microwave ablation technology is improved to a new step by means of the scope, and the new technology is more intuitive to direct microwave radiation antenna to tumor and pathological tissues by means of the scope. This requires a flexible ablation needle shaft that can freely pass through the endoscope. Meanwhile, the ablation needle is required to have certain puncture force, and different ablation needles are also necessary to be provided for different parts. Because some organs of the thoracic cavity and the abdominal cavity can directly reach the pathological change part by means of an ultrasonic endoscope, a short hard needle in the market is unable, a flexible endoscope ablation needle appears, a preferred treatment scheme is added for doctors and patients, the clinic has been accepted, and due to the increasing importance of people on health, lung cancer, liver cancer and pancreatic cancer are increased in society, and the flexible endoscope ablation needle has a wide market prospect.
Disclosure of Invention
The invention aims to provide an ablation needle with good flexibility, compared with the existing microwave ablation needle, the ablation needle can effectively solve the problem that the ablation needle is difficult to puncture and insert into a needle to position, and the ablation needle can reach more lesion sites and has strong penetrability.
The technical scheme adopted by the invention is as follows: the utility model provides a flexible microwave ablation needle under ultrasonic endoscope, includes handle, radio frequency coaxial connector and microwave radiation antenna, the radio frequency coaxial connector set up in on the handle, the radio frequency coaxial connector with microwave radiation antenna passes through the radio frequency coaxial cable and is connected, the radio frequency coaxial cable periphery is equipped with capillary and inner tube in proper order, the radio frequency coaxial cable is arranged in the capillary, the capillary is arranged in the inner tube, the capillary is as cooling water passageway intercommunication has the inlet tube, the capillary outer wall with the inner tube inner wall forms the drainage pipe, the drainage pipe intercommunication has the outlet pipe, gets into cooling water passageway's water warp the drainage pipe discharges, the inner tube includes first tip and second tip, first tip extends to microwave radiation antenna, the second tip is kept away from microwave radiation antenna, the inner tube by the second tip extremely first tip tapers.
Further, the inner tube material is a material which is resistant to high temperature and can be bent freely, such as polyphenylene ether ketone or polyimide.
Furthermore, the capillary tube is made of a material which is resistant to high temperature and can be bent freely, such as a nickel titanium alloy tube or polyphenyl ether ketone or polyimide, and the capillary tube is coated outside the microwave radiation antenna.
Further, an outer tube is arranged outside the inner tube, the outer tube is sleeved outside the inner tube, and the inner diameter of the outer tube is larger than the outer diameter of the inner tube.
Further, the outer tube tapers from an end remote from the microwave radiating antenna to an end proximate to the microwave radiating antenna.
Further, the outer tube material is a material which is resistant to high temperature and can be bent freely, such as polyphenylene ether ketone or polyimide.
Further, the handle includes first handle, flexible handle and second handle, the coaxial connector of radio frequency set up in on the first handle, be equipped with the first through-hole that runs through both ends in the flexible handle, the second handle is equipped with the second through-hole that runs through both ends, radio frequency coaxial cable, capillary and inner tube pass in proper order by first handle first through-hole on the flexible handle and the second through-hole on the second handle outwards extend, flexible handle sliding connection first handle or second handle, the slip direction with the coaxial cable axial of radio frequency is unanimous.
Further, the telescopic handle is connected with the first handle in a sliding manner.
Further, a locking device for preventing the telescopic handle and the first handle from sliding relatively is arranged between the telescopic handle and the first handle.
Further, an isolation cavity is arranged on the handle and comprises a water inlet cavity and a water outlet cavity which are mutually separated, the water inlet cavity is communicated with the water inlet pipe and the capillary tube, and the water outlet cavity is communicated with the water drainage pipeline and the water outlet pipe.
The beneficial effects of the invention include: 1. the inner tube adopts gradual change diameter, so that the front end is thin and the rear end is thick, the front end can be bent under the condition of ensuring the required strength of the inner tube, more lesion parts can be achieved, and the penetrability of the inner tube is increased by the design; 2. the invention fully utilizes the pipeline between the inner pipe and the capillary tube as the cooling water drainage channel, so that the cooling water in the capillary tube flows to the microwave radiation antenna and is discharged by the drainage channel, the cooling water channel and the drainage channel are mutually separated, and the cooling efficiency is ensured; 3. the water inlet pipe and the water outlet pipe are arranged on the same side, so that the water can be conveniently managed; 4. the outer tube is arranged outside the inner tube and is consistent with the thickness variation trend of the inner tube, so that on one hand, the microwave radiation antenna and the reducing inner tube are protected from being damaged by external force, and the reducing inner tube is also used as a free telescopic channel of the reducing inner tube, and on the other hand, the outer tube is used for isolating the microwave radiation antenna and preventing the inner wall of the ultrasonic endoscope from being damaged; 5. the invention adopts the design of the telescopic handle, and can change the length of the microwave radiation antenna penetrating into the body by changing the relative position of the first handle and the telescopic handle, thereby realizing the telescopic function; 6. the isolation cavity in the invention enables the separation design of the water inlet cavity and the water outlet cavity to effectively reduce the rod temperature, thereby reducing the damage of energy consumption to the endoscope and normal tissues in the microwave ablation process.
Drawings
FIG. 1 is a schematic view of a flexible microwave ablation needle in accordance with the present invention;
FIG. 2 is a cross-sectional view of the needle shaft of the present invention;
FIG. 3 is an enlarged view of a microwave radiating antenna in the present invention;
FIG. 4 is an enlarged view of an isolated cavity in the present invention;
FIG. 5 is a schematic view of the handle structure of the present invention;
in the figure, 1, a first handle, 2, a telescopic rod, 3, a second handle, 4, a water inlet pipe, 5, a water outlet pipe, 6, an isolation cavity, 601, a water inlet cavity, 602, a water outlet cavity, 7, a radio frequency coaxial connector, 8, a radio frequency coaxial cable, 9, a microwave radiation antenna, 10, a capillary tube, 11, an inner pipe, 12, an outer pipe, 13, a temperature sensor, 14, a clamping ring, 15, a cooling water channel, 16, a water outlet channel, 17, a first through hole, 18 and a second through hole.
Detailed Description
The invention will be explained in further detail below with reference to the drawings and the embodiments, but it should be understood that the scope of protection of the invention is not limited by the embodiments.
As shown in fig. 1, the flexible microwave ablation needle under the ultrasonic endoscope comprises a handle, a radio frequency coaxial connector 7, a radio frequency coaxial cable 8, a microwave radiation antenna 9, a capillary tube 10 and an inner tube 11, wherein the radio frequency coaxial connector 7 is arranged on the handle, one end of the radio frequency coaxial cable 8 is connected with the radio frequency coaxial connector 7, the other end of the radio frequency coaxial cable is connected with the microwave radiation antenna 9, the microwave radiation antenna 9 is an energy emitter and is used for emitting ablated microwaves, and the structure of the flexible microwave ablation needle can be designed according to different requirements, adopts a triangular pyramid antenna or an inclined plane or a conical shape, and has an excellent puncture function. The radio frequency coaxial cable 8 passes through the capillary 10 and is a microwave radiation channel for connecting the microwave radiation antenna 9 and the radio frequency coaxial connector 7; the copper-clad steel double-layer shielding sheath tube has high dielectric constant, microwave leakage prevention, an outer copper shielding sheath tube, a middle polytetrafluoroethylene dielectric layer and an inner core which are made of silver-clad steel, and is double-layer protection. The capillary tube 10 is arranged in the inner tube 11 and extends from the handle end to the microwave radiation antenna 9, the capillary tube 10 is coated outside the radio frequency coaxial cable 8, the capillary tube 10 is used as a cooling water channel 15 to be connected with the water inlet tube 4, and cooling water enters the capillary tube 10 to cool the radio frequency coaxial cable 8, so that the rod temperature is ensured not to be too high. The inner tube 11 is coated outside the capillary tube 10, a drainage channel 16 is formed by the inner wall of the inner tube 11 and the outer wall of the capillary tube 10, the drainage channel 16 is communicated with the water outlet pipe 5, cooling water enters from one end of the capillary tube 10, flows out from the other end and then enters the drainage channel 16, and then is discharged from the water outlet pipe 5.
The inner tube 11 is arranged in a reducing form, extends to the microwave radiation antenna 9 from a handle end, is connected with the microwave radiation antenna 9 to form a first end, is connected with the handle end to form a second end, and gradually tapers from the second end to the first end to form a pipe diameter (including an inner diameter and an outer diameter) of the inner tube 11 to be about 1mm, so that the thin end of the inner tube 11 can be bent to reach more lesion parts, and in order to ensure the flexibility of the inner tube 11, the inner tube 11 is made of a material which is high-temperature resistant and can be bent freely, such as PEEK (polyphenylene ether ketone) or PI (polyimide) materials, and has good flexibility. The inner tube 11 not only plays a role of protecting the capillary tube 10 and the radio frequency coaxial cable 8, but also ensures the mutual separation of the cooling water channel 15 and the drainage channel 16 by the drainage channel 16 formed with the inner wall of the capillary tube 10, thereby ensuring the cooling efficiency.
In order to ensure the flexibility of the capillary tube 10, the capillary tube 10 is made of a material which is resistant to high temperature and can be bent freely, such as a nickel titanium alloy tube or polyphenyl ether ketone or polyimide, and the tube has the function of being bent freely and can be recovered, so that the needle bar is prevented from being deformed.
As shown in fig. 2, the needle bar structure in the invention is that an outer tube 12 is coated with an inner tube 11, the inner tube 11 is coated with a capillary tube 10, the capillary tube 10 is coated with a radio frequency coaxial cable 8, the capillary tube 10 is used as a cooling water channel 15, the outer wall of the capillary tube 10 and the inner wall of the inner tube 11 form a drainage channel 16, the outer tube 12 in the invention is consistent with the inner tube 11 and gradually tapers from one end to the other end, the outer tube 12 is made of a material which is high-temperature resistant and can be freely bent, such as PEEK (polyphenylene ether ketone) or PI (polyimide), the outer diameter of the outer tube 12 is 3.7mm at most, the outer tube 12 has good overbending property and double protection effects, on one hand, the microwave radiation antenna 9 and the variable diameter inner tube 11 are protected from external force damage, and the variable diameter inner tube 11 is also used as a freely telescopic channel for isolating the microwave radiation antenna from damaging the inner wall of an ultrasonic endoscope. The whole length from the handle to the microwave radiation antenna reaches more than 1.5 m.
As shown in fig. 3, the microwave radiation antenna 9 is a triangular pyramid antenna, a bevel antenna or a cone antenna, and has an excellent puncture function. The temperature sensor 13 is arranged on the needle bar, the temperature sensor 13 extends to the front end of the microwave radiation antenna, the temperature of the bar is accurately monitored in real time, the damage of normal tissues and the damage of an endoscope caused by the overhigh temperature of the bar are prevented, the temperature exceeds a set value, and the feedback control system cuts off microwave output.
As shown in fig. 4, an isolation cavity 6 is arranged in the handle, the isolation cavity 6 comprises a water inlet cavity 601 and a water outlet cavity 602 which are mutually separated, the water inlet cavity 601 is ensured to be communicated with the capillary tube 10, the water outlet cavity 602 is communicated with a drainage pipeline, and cooling water after cold-heat exchange is led out after a loop is formed, so that the temperature of a needle bar is reduced. The inlet pipe 4 is connected to the inlet chamber 601, and outlet pipe 5 is connected to the outlet chamber 602, keeps apart chamber 6 and lets inlet water and play water isolation, can effectively reduce the pole temperature, and capillary 10 and inner tube 11 are independently connected with the chamber 6 respectively as the circulative cooling passageway, can save space, lets the scope ablate the needle and make finer, guarantees good bending property, the conversion direction of freedom in the scope.
As shown in fig. 5, the handle in the invention comprises a first handle 1, a telescopic handle 2 and a second handle 3, the telescopic handle 2 is connected with the first handle 1 and the second handle 3, a radio frequency coaxial connector 7 and an isolation cavity 6 are arranged in the first handle 1, a first through hole 17 penetrating through two ends is arranged in the telescopic handle 2, a second through hole 18 penetrating through two ends is arranged in the second handle 3, a radio frequency coaxial cable 8 sequentially penetrates through the first through hole 17 and the second through hole 18 from the first handle 1 to extend towards the other end, a capillary 10 is consistent with an inner tube 11, the capillary 10 extends from a water inlet cavity 601 of the isolation cavity 6 to a microwave radiation antenna 9, the inner tube 11 extends from a water outlet cavity 602 of the isolation cavity 6 to the microwave radiation antenna 9, an outer tube 12 is fixed at one end of the second handle 3 far away from the telescopic handle 2, the outer tube 12 is communicated with the second through hole 18, the outer tube 12 and the second handle 3 are integrally arranged, the outer tube 12 gradually tapers from the end of the second handle 3, and the whole length from the handle to the other end reaches more than 1.5 m.
In order to ensure that the microwave radiation antenna 9 is telescopic in a human body, the telescopic handle 2 is in sliding connection with the first handle 1, one end of the first handle 1, which is connected with the telescopic handle 2, is hollow, one end of the telescopic handle 2 stretches into the hollow area of the first handle 1, and the depth of the microwave radiation antenna 9 stretching into the human body is adjusted by changing the length of the telescopic handle 2 stretching into the first handle 1, namely changing the distance between the first handle 1 and the second handle 3.
In order to be convenient for fix the relative position of two after adjusting the length that flexible handle 2 in deep into first handle 1, set up locking device between the two, locking device specifically adopts the draw-in groove to fix between flexible handle 2 and first handle 1, and the one end of connecting flexible handle 2 at first handle 1 sets up snap ring 14, and flexible handle 2 passes snap ring 14 and deep into first handle 1 sky area, sets up the draw-in groove at flexible handle 2 outer wall, sets up in the corresponding lug of draw-in groove at snap ring 14 inner wall, and the position between flexible handle 2 and the first handle 1 is relatively fixed after the draw-in groove card income lug. In order to clearly know the penetration length of the needle rod, the scales on the telescopic handle 2 can clearly indicate the needle penetration depth of the ablation needle.
The specific structure is that the snap ring 14 is pressed down, the first handle 1 can bring the isolation cavity 6, the reducing inner tube 11 and the corresponding microwave radiation antenna slide together, the snap ring 14 is loosened, the telescopic handle 2 is provided with a saw-tooth clamping groove, the elastic buckle is embedded into the clamping groove of the telescopic handle 2, and the telescopic handle 2 is fixed in real time to prevent the telescopic handle from moving forwards and backwards. The elastic buckle is arranged in the clamping ring 14, the clamping groove is disengaged by pressing the elastic buckle arranged in the clamping ring 14, the clamping ring 14 is loosened, the elastic buckle elastically clamps the clamping groove of the telescopic handle 2 by the elastic buckle, and the structure is similar to a quick plug-in connector structure with locking.
According to the invention, a special reducing inner and outer tube structure is adopted, the reducing outer tube 12 is sleeved outside the reducing inner tube 11, a special channel is formed to be isolated from the outside, on one hand, the heating reducing inner tube 11 and an endoscope forceps channel during ablation are isolated, on the other hand, the endoscope is effectively protected, on the other hand, the triangular pyramid structure of the microwave radiation antenna 9 and the reducing inner tube 11 with the front end being thinned by a thick thickness effectively reduce puncture resistance, the penetration of lesion tissues is facilitated, the internal ablation is performed, meanwhile, the PTFE reducing material enables the bent flexible ablation needle to recover to a state without influencing the cooling ablation effect.
Compared with the existing microwave ablation needle, the invention can effectively solve the problems of difficult puncture and difficult needle insertion and positioning, but can intuitively and clearly reach the focus position by means of endoscope positioning, then the flexible microwave ablation needle is sent to the focus position through an ultrasonic endoscope forceps channel, and meanwhile, the unique isolation multi-cavity structure can effectively reduce the rod temperature and reduce the damage of energy consumption to an endoscope and normal tissues in the microwave ablation process.
The working principle of the invention is as follows: in two steps
Power signal: microwave output equipment- & gt, through a radio frequency coaxial connector 7- & gt, a radio frequency coaxial cable 8- & gt, passing through a handle- & gt, entering an isolation cavity 6- & gt, an inner pipe 11- & gt, and radiating energy by a microwave radiation antenna 9;
protection circuit: the temperature of backwater in the drainage pipeline, the temperature measurement of the temperature sensor 13, the exceeding of the rod temperature by the set value, the feedback of the microwave output equipment and the cutting off of the microwave output.
Cooling circulation loop: the water inlet pipe 4, the water inlet cavity 601 in the isolation cavity 6, the capillary tube 10, the inner tube 11, the temperature sensor 13 for detecting the rod temperature, the water outlet cavity 602 in the isolation cavity 6, the backwater after heat exchange and the water outlet pipe 5.
The above is only a preferred embodiment of the present invention, and the present invention is not limited to the contents of the embodiment. Various changes and modifications within the technical scope of the present invention will be apparent to those skilled in the art, and any changes and modifications are intended to be within the scope of the present invention.

Claims (8)

1. A flexible microwave ablation needle under ultrasonic endoscope is characterized in that:
the microwave radiation device comprises a handle, a radio frequency coaxial connector and a microwave radiation antenna, wherein the radio frequency coaxial connector is arranged on the handle, the radio frequency coaxial connector is connected with the microwave radiation antenna through a radio frequency coaxial cable, a capillary tube and an inner tube are sequentially arranged on the periphery of the radio frequency coaxial cable, the radio frequency coaxial cable is arranged in the capillary tube, the capillary tube is arranged in the inner tube, the capillary tube is used as a cooling water channel to be communicated with a water inlet pipe, the outer wall of the capillary tube and the inner wall of the inner tube form a drainage pipeline, the drainage pipeline is communicated with a water outlet pipe, water entering the cooling water channel is discharged through the drainage pipeline, the inner tube comprises a first end part and a second end part, the first end part extends to the microwave radiation antenna, the second end part is far away from the microwave radiation antenna, and the inner tube is gradually thinned from the second end part to the first end part;
the inner pipe material is a material which is resistant to high temperature and can be freely bent;
the handle comprises a first handle, a telescopic handle and a second handle, the radio frequency coaxial connector is arranged on the first handle, a first through hole penetrating through two ends is formed in the telescopic handle, a second through hole penetrating through two ends is formed in the second handle, the radio frequency coaxial cable, the capillary tube and the inner tube sequentially penetrate through the first through hole in the telescopic handle and the second through hole in the second handle through the first handle to extend outwards, the telescopic handle is connected with the first handle or the second handle in a sliding mode, and the sliding direction is consistent with the axial direction of the radio frequency coaxial cable.
2. The ultrasonic endoscopic flexible microwave ablation needle according to claim 1, wherein:
the capillary tube is made of a material which is resistant to high temperature and can be bent freely, and the capillary tube is coated outside the microwave radiation antenna.
3. The ultrasonic endoscopic flexible microwave ablation needle according to claim 1, wherein:
the outer tube is arranged outside the inner tube, the outer tube is sleeved outside the inner tube, and the inner diameter of the outer tube is larger than the outer diameter of the inner tube.
4. A flexible microwave ablation needle according to claim 3, wherein:
the outer tube tapers from an end remote from the microwave radiating antenna to an end proximate to the microwave radiating antenna.
5. The flexible microwave ablation needle under an ultrasonic endoscope according to claim 3 or 4, wherein:
the outer tube material is a material which is resistant to high temperature and can be freely bent.
6. The ultrasonic endoscopic flexible microwave ablation needle according to claim 1, wherein:
the telescopic handle is connected with the first handle in a sliding manner.
7. The ultrasonic endoscopic flexible microwave ablation needle according to claim 6, wherein:
a locking device for preventing the telescopic handle and the first handle from sliding relatively is arranged between the telescopic handle and the first handle.
8. The ultrasonic endoscopic flexible microwave ablation needle according to claim 1, wherein:
the handle is provided with an isolation cavity, the isolation cavity comprises a water inlet cavity and a water outlet cavity which are mutually separated, the water inlet cavity is communicated with the water inlet pipe and the capillary, and the water outlet cavity is communicated with the drainage pipeline and the water outlet pipe.
CN201810833418.9A 2018-07-26 2018-07-26 Flexible microwave ablation needle under ultrasonic endoscope Active CN108938080B (en)

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CN201810833418.9A CN108938080B (en) 2018-07-26 2018-07-26 Flexible microwave ablation needle under ultrasonic endoscope
PCT/CN2019/097425 WO2020020205A1 (en) 2018-07-26 2019-07-24 Endoscopic ultrasonography flexible microwave ablation needle

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Application Number Priority Date Filing Date Title
CN201810833418.9A CN108938080B (en) 2018-07-26 2018-07-26 Flexible microwave ablation needle under ultrasonic endoscope

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CN108938080B true CN108938080B (en) 2024-02-09

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CN108938080A (en) 2018-12-07

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