CN108931657A - A kind of cross matching instrument - Google Patents

A kind of cross matching instrument Download PDF

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Publication number
CN108931657A
CN108931657A CN201810344556.0A CN201810344556A CN108931657A CN 108931657 A CN108931657 A CN 108931657A CN 201810344556 A CN201810344556 A CN 201810344556A CN 108931657 A CN108931657 A CN 108931657A
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China
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storage box
serum
drawing liquid
annular
entrance
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CN108931657B (en
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王云
宋玉庚
王民
叶光勇
洪凡
王子睿
郑棱楠
余忠良
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Hangzhou Dianzi University
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Hangzhou Dianzi University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

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  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
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  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
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  • Food Science & Technology (AREA)
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  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of cross matching instrument.Before blood transfusion, needs profession to survey teacher and complete Blood grouping and cross matching experiment in the laboratory of profession.The present invention includes support frame, reagent absorption addition mechanism, the first serum the storage box, the second serum the storage box, physiological saline Storage Box, low ionic medium Storage Box, cohesion amine aqueous solution Storage Box and suspension Storage Box.It includes reagent disc, layering collector, Multi-layer technology pipe, cohesion amine mediator agents adding tube and serum adding tube that reagent, which draws addition mechanism,.Six mounting holes circumferentially uniformly distributed along reagent disk axis are offered on the bottom surface of reagent disc;Six mounting holes are blind hole, and bottom is respectively and fixedly provided with permanent magnetic steel.The top of cohesion amine mediator agents adding tube, three layering collectors and two serum adding tubes is embedded with Attraction block.The present invention can assist personnel complete Blood grouping and cross match blood test, greatly simplified the workload of medical staff during match.

Description

A kind of cross matching instrument
Technical field
The invention belongs to blood testing technical fields, and in particular to a kind of cross matching instrument.
Background technique
When carrying out treatment of blood transfusion to patient, first it is to be understood that the blood group of patient, then will also pass through cross match blood test Confirm the antigen-antibody reaction that blood group incompatibility is not present between receptor and blood donor, further to guarantee the blood transfusion of receptor Safety.Present treatment of blood transfusion mostly based on component blood transfusion, and in clinical application mostly with plasma transfusion and two class blood of red blood cell at Divide most commonly seen.Although presently, there are with the instrument for carrying out detection and cross matching function to blood group, part instrument function Can be various, it is inconvenient, but also it is chiefly used in batch detection, hospital can seldom encounter such a large amount of patient again in practice, Therefore most of hospital is seldom gone in practice using these instruments.This can only survey teacher by profession and complete in the laboratory of profession Blood grouping and cross match blood test, and the process detected is relatively complicated, there are artificial operation errors, by the treatment to patient It is very unfavorable.
Summary of the invention
The purpose of the present invention is to provide a kind of cross matching instrument.
The present invention includes support frame, reagent absorption addition mechanism, the first serum the storage box, the second serum the storage box, physiology Saltwater-storage box, low ionic medium Storage Box, cohesion amine aqueous solution Storage Box and suspension Storage Box.The reagent draws addition Mechanism includes reagent disc, layering collector, Multi-layer technology pipe, cohesion amine mediator agents adding tube and serum adding tube;Described Reagent disc and supporting framework are at revolute pair.Physiological saline Storage Box, the first serum the storage box, the second serum the storage box, low ion Medium Storage Box, cohesion amine aqueous solution Storage Box and suspension Storage Box are each attached on reagent disc;The physiological saline storage Box memory is placed with physiological saline;First serum the storage box is provided with A serum;Second serum the storage box is provided with B serum;Low ion Medium Storage Box is provided with low ionic medium.Cohesion amine aqueous solution Storage Box is provided with cohesion amine aqueous solution.Suspension Storage Box is built-in There is suspension.
Six mounting holes circumferentially uniformly distributed along reagent disk axis are offered on the bottom surface of the reagent disc;Six mounting holes are equal For blind hole, and bottom is respectively and fixedly provided with permanent magnetic steel.Cohesion amine mediator agents adding tube, three layering collectors and two serum add The top of pipe is added to be embedded with Attraction block.
Fluid-through chamber is offered inside the layering collector.The bottom end of fluid-through chamber and the bottom end end face of layering collector connect Logical, top is connected to the physiological saline entrance for being provided with layering collector lateral surface top.It is layered on the lateral surface of collector and opens Equipped with along itself four circumferentially uniformly distributed sliding slot;The length direction of four sliding slots is along the axis direction setting of layering collector; Four drawing liquid sliding blocks and four sliding slots respectively constitute sliding pair;Drawing liquid electromagnet is respectively and fixedly provided at the top of four sliding slots;Drawing liquid is sliding Block is permanent magnet;The bottom of four drawing liquid sliding block lateral surfaces is provided with kelly protrusion;The drawing liquid that two of them are oppositely arranged is sliding Block composition is lower to drive drawing liquid sliding block group;Drawing liquid sliding block group is driven on the drawing liquid sliding block composition that another two is oppositely arranged;Lower driving is taken out Kelly protrusion in liquid sliding block group on two drawing liquid sliding blocks is aligned on the axis direction of layering collector;Upper driving drawing liquid sliding block Kelly protrusion in group on two drawing liquid sliding blocks is aligned on the axis direction of layering collector;Two in lower driving drawing liquid sliding block group Kelly protrusion in kelly protrusion and upper driving drawing liquid sliding block group on a drawing liquid sliding block on two drawing liquid sliding blocks is acquired in layering The axis direction of device is arranged in a staggered manner;Kelly slot is offered in four kelly protrusions;It is layered on the bottom end end face of collector and is fixed with Rubber connection ring;The first feed liquor button and two drawing liquid switches are provided on layering collector.Drawing liquid switch is stirred using three Switch.
The liquid outlet of physiological saline entrance and three the first micropumps on three layering collectors is connected by hose respectively It is logical;The liquid inlet of three the first micropumps is connected to the inner cavity of physiological saline Storage Box;The bottom end of three layering collectors is equal Multi-layer technology pipe is installed;The extraction chamber for being internally provided with bottom closing, open-top of Multi-layer technology pipe;In Multi-layer technology pipe It extracts and is provided with connection hole at the top of chamber;Connection hole aperture is equal to the outer diameter of rubber connection ring;The extraction of Multi-layer technology pipe It is intracavitary to be fixed with Brine Pipe;The Brine Pipe is divided into the salt water cavity inside Brine Pipe and the ring outside Brine Pipe for chamber is extracted Shape is layered chamber;Annular partition plate is fixed in the middle part of annular segment chamber;Annular segment chamber is divided into annular by annular partition plate Chamber and annular cavity of resorption;Salt water cavity is connected to annular cavity of resorption by the first check valve;The entrance of first check valve is towards salt water cavity;Ring It is intracavitary in shape to be provided with first annular piston;It is intracavitary under annular to be provided with the second annular piston.
Gas outlet and lower gas outlet are offered on the lateral wall of the Multi-layer technology pipe;On Multi-layer technology pipe lateral wall with The corresponding position in annular cavity of resorption bottom offers lower inlet;Position corresponding with annular epicoele bottom on Multi-layer technology pipe lateral wall It sets and offers inlet;Lower liquid outlet and upper liquid outlet are offered on the bottom end end face of Multi-layer technology pipe;Lower inlet and under Liquid outlet is connected to the bottom of annular cavity of resorption;Upper inlet and upper liquid outlet are connected to the bottom of annular epicoele;Upper outlet Mouth is connected to the top of annular epicoele;Lower gas outlet is connected to the top of annular cavity of resorption;It is unidirectional that third is fixed in lower inlet Valve;It is intracavitary under the outlet direction annular of third check valve;The 4th check valve is fixed in lower liquid outlet;The entrance of 4th check valve It is intracavitary under towards annular;The 5th check valve is fixed in upper inlet;The outlet of 5th check valve is upper intracavitary towards annular;Above go out The 6th check valve is fixed in liquid mouth;The entrance of 6th check valve is upper intracavitary towards annular;First annular piston and two first The bottom end of pull rod is fixed;The bottom end of second annular piston and two second pull rods is fixed;Two first pull rods and two second drawings The top of bar is respectively and fixedly provided with cross bar;Cross bar on two first pull rods, which is respectively clamped on corresponding, drives two drawing liquids in sliding block group sliding The kelly slot of kelly protrusion on block;It is sliding that cross bar on two second pull rods is respectively clamped into two drawing liquids in corresponding lower driving sliding block group The kelly slot of kelly protrusion on block.
Offered in cohesion amine mediator agents adding tube mutual independent low ionic medium channel, cohesion amine aqueous solution channel and Suspension passage;Low ionic medium channel, cohesion amine aqueous solution channel, the bottom end of suspension passage and entering for three the 7th check valves Mouth is respectively communicated with, and top is layered the low ionic medium entrance on collector lateral surface top with being provided with, cohesion amine aqueous solution entrance, hangs Supernatant liquid entrance is respectively communicated with;Three the 7th check valves are arranged on the bottom end end face of cohesion amine mediator agents adding tube.It is low from It is provided in sub- medium channel, cohesion amine aqueous solution channel and suspension passage and propels component;Propelling component includes propelling electromagnetism Iron propels bar, propels spring, cohesion amine piston and second one-way valve;It propels bar and propels electromagnet and constitute sliding pair;Propel bullet Spring is nested on propelling bar, and both ends are fixed respectively with propelling bar, propel electromagnet;The bottom end for propelling bar, which passes through, propels electromagnetism Iron, and fixed with cohesion amine piston;The top of cohesion amine piston, which is embedded with, propels iron block;It propels in component for three and propels electromagnet The top for being separately fixed at low ionic medium channel, agglomerating amine aqueous solution channel, suspension passage;Three cohesions propelled in component Amine piston and low ionic medium channel, cohesion amine aqueous solution channel, suspension passage respectively constitute sliding pair;Low ionic medium enters Second one-way valve is respectively and fixedly provided on mouth, cohesion amine aqueous solution entrance and suspension inlet.The entrance of second one-way valve is respectively facing low Ionic medium channel, cohesion amine aqueous solution channel, in suspension passage.Three propel component be respectively higher than low ionic medium entrance, Agglomerate amine aqueous solution entrance, suspension inlet.Agglomerating setting in amine mediator agents adding tube, there are three the second feed liquor buttons.Agglomerate amine Low ionic medium entrance, cohesion amine aqueous solution entrance, suspension inlet and the low ion on mediator agents adding tube lateral surface top are situated between Matter Storage Box, cohesion amine aqueous solution Storage Box, suspension Storage Box inner cavity respectively pass through hose be connected to.
Serum channel is offered in serum adding tube.The bottom end in serum channel is connected to the bottom end end face of layering collector, Top is connected to the serum entrance for being provided with serum adding tube lateral surface top.The serum entrance of two serum adding tubes and two The liquid outlet of second micropump is respectively communicated with.The liquid inlet of two the second micropumps is deposited with the first serum the storage box, the second serum The inner cavity of storage box is respectively communicated with.Third feed liquor button is provided in serum adding tube.
Further, the support frame include upper mounting ring, under put ring and support column.The bottom end of three support columns is equal It puts ring under to fix, top is fixed with upper mounting ring.
Further, the Attraction block uses magnetic material or permanent magnet.
Further, one end of the kelly slot is connected to the rod end end face that enters of kelly protrusion;Kelly protrusion enters rod end end The connectivity part of face and kelly slot is equipped with chamfering;The distance of the upper liquid outlet and lower liquid outlet to Multi-layer technology pipe axis is big In the radius of annular cavity of resorption.
The invention has the advantages that:
1, the present invention can assist personnel complete Blood grouping and cross match blood test, greatly simplified match The workload of medical staff in journey.
2, present invention is generally directed to single Blood grouping and cross match blood test, it is more in line with practical application, and can Artificial operation error is avoided, keeps test result more accurate, also improves efficiency, is more advantageous to the treatment to patient.
3, the Multi-layer technology pipe that blood can be contacted in the present invention is disposable device, and replaces very convenient, guarantee The reliability of test result
Detailed description of the invention
Fig. 1 is perspective view of the invention;
Fig. 2 is the perspective view that the present invention removes support frame;
Fig. 3 is the combination diagram that collector and Multi-layer technology pipe are layered in the present invention;
Fig. 4 is the enlarged view of part A in Fig. 3;
Fig. 5 is the cross-sectional view of Multi-layer technology pipe in the present invention;
Fig. 6 is the perspective view that electromagnet is propelled in the present invention.
Specific embodiment
Below in conjunction with attached drawing, the invention will be further described.
As shown in Figure 1, a kind of cross matching instrument, including support frame, reagent draw addition mechanism 6, the first serum the storage box 4, the second serum the storage box 5, physiological saline Storage Box 7, low ionic medium Storage Box 8, cohesion amine aqueous solution Storage Box 9 and suspension Storage Box 10.Support frame include upper mounting ring 1, under put ring 2 and support column 3.Ring is put under in the bottom end of three support columns 3 2 is fixed, and top is fixed with upper mounting ring 1.
As shown in Figure 1,2 and 3, it includes reagent disc 6-1, layering collector 6-2, Multi-layer technology that reagent, which draws addition mechanism 6, Pipe 6-8, cohesion amine mediator agents adding tube 6-3 and serum adding tube 6-4.Reagent disc 6-1 and upper mounting ring 1 are constituted with reagent disc 6-1 central axis is the revolute pair of common axis.Physiological saline resettlement groove, the first serum are offered on the top surface of reagent disc 6-1 Resettlement groove, the second serum resettlement groove, low ionic medium resettlement groove, cohesion amine aqueous solution resettlement groove and suspension resettlement groove.Physiology salt Water Storage Box 7 is fixed in physiological saline resettlement groove.First serum the storage box 4 is fixed in the first serum resettlement groove.Second blood Clear the storage box 5 is fixed in the second serum resettlement groove.7 memory of physiological saline Storage Box is placed with physiological saline.The storage of first serum Box 4 is provided with the A serum for blood group examination.Second serum the storage box 5 is provided with the B serum for blood group examination.Low ion Medium Storage Box 8 is fixed in low ionic medium resettlement groove.Cohesion amine aqueous solution Storage Box 9 is fixed on cohesion amine aqueous solution resettlement groove It is interior.Suspension Storage Box 10 is fixed in suspension resettlement groove.Low ionic medium Storage Box 8 is provided with low ionic medium (grape The mixed liquor of sugar, EDTA (2Na), NaN3).Cohesion amine aqueous solution Storage Box 9 be provided with cohesion amine aqueous solution (cohesion amine, sodium chloride, The mixed liquor of NaN3).Suspension Storage Box 10 be provided with suspension (glucose, trisodium citrate, NaN3 mixed liquor).
Six mounting holes circumferentially uniformly distributed along reagent disc 6-1 axis are offered on the bottom surface of reagent disc 6-1.Six mounting holes It is blind hole, and bottom is respectively and fixedly provided with permanent magnetic steel 6-5.Agglomerate amine mediator agents adding tube 6-3, three layering collector 6-2 And the top of two serum adding tube 6-4 is embedded with Attraction block.Attraction block uses magnetic material or permanent magnet, adopts in the present embodiment Use iron block.Cohesion amine mediator agents adding tube 6-3, three layering collector 6-2, two serum adding tubes are respectively clamped into six peaces Hole is filled, and six permanent magnetic steel 6-5 are attracted respectively with six pieces of Attraction blocks.
As shown in Fig. 1,2,3 and 4, layering collector 6-2 is cylindrical, and inside offers fluid-through chamber.The bottom of fluid-through chamber It holds and is connected to the bottom end end face of layering collector 6-2, top and the physiological saline for being provided with layering collector 6-2 lateral surface top Entrance connection.It is layered on the lateral surface of collector 6-2 and offers along itself four circumferentially uniformly distributed sliding slot.The length of four sliding slots Direction is along the axis direction setting of layering collector 6-2.Four drawing liquid sliding block 6-9 and four sliding slots respectively constitute sliding pair. Drawing liquid electromagnet is respectively and fixedly provided at the top of four sliding slots.Drawing liquid sliding block 6-9 is permanent magnet.One of magnetic of drawing liquid sliding block 6-9 Pole is towards surface.The bottom of four drawing liquid sliding block 6-9 lateral surfaces is provided with kelly protrusion 6-10.Two of them are oppositely arranged Drawing liquid sliding block composition lower drive drawing liquid sliding block group.Drawing liquid sliding block group is driven on the drawing liquid sliding block composition that another two is oppositely arranged. Kelly protrusion 6-10 in lower driving drawing liquid sliding block group on two drawing liquid sliding block 6-9 is in the axis direction pair for being layered collector 6-2 Together.Kelly protrusion 6-10 in upper driving drawing liquid sliding block group on two drawing liquid sliding block 6-9 is in the axis direction for being layered collector 6-2 Upper alignment.In kelly protrusion 6-10 and upper driving drawing liquid sliding block group in lower driving drawing liquid sliding block group on two drawing liquid sliding block 6-9 Kelly protrusion 6-10 on two drawing liquid sliding block 6-9 is arranged in a staggered manner on the axis direction of layering collector 6-2.Four kellies are convex It rises and offers kelly slot on 6-10.One end of kelly slot is connected to the rod end end face that enters of kelly protrusion 6-10.Kelly protrusion 6-10 The connectivity part for entering rod end end face and kelly slot is equipped with chamfering.It is layered on the bottom end end face of collector 6-2 and is fixed with rubber connection ring. The first feed liquor button and two drawing liquid switches are provided on layering collector 6-2.Drawing liquid switch uses three toggle switches.First Feed liquor button is used to control the starting or closing of corresponding first micropump.One of drawing liquid switch is taken out for controlling upper driving The forward and reverse energization or power-off of the corresponding two drawing liquid electromagnet of liquid sliding block group.Another drawing liquid switch is taken out for controlling lower driving The forward and reverse energization or power-off of the corresponding two drawing liquid electromagnet of liquid sliding block group.
As shown in Fig. 1,2,3,4 and 5, physiological saline entrance on three layering collectors and three the first micropumps Liquid outlet is connected to by hose respectively;The liquid inlet of three the first micropumps is connected to physiological saline Storage Box;Three layerings The bottom end of collector 6-2 is mounted on Multi-layer technology pipe 6-8.Multi-layer technology pipe 6-8's is internally provided with that bottom closing, top opens The extraction chamber put.The connection hole that insertion rubber connection ring is provided at the top of chamber is extracted in Multi-layer technology pipe 6-8.Connection hole Aperture be equal to rubber connection ring outer diameter.The connection hole of Multi-layer technology pipe 6-8 is put on into rubber connection ring, it can be by rubbing Wipe the connection that power realizes layering collector 6-2 and Multi-layer technology pipe 6-8.The extraction of Multi-layer technology pipe 6-8 is intracavitary to be fixed with salt water Pipe 6-11.Brine Pipe 6-11 is divided into the annular outside salt water cavity and Brine Pipe 6-11 inside Brine Pipe 6-11 point for chamber is extracted Layer chamber.Annular partition plate 6-12 is fixed in the middle part of annular segment chamber.Annular segment chamber is divided into ring by annular partition plate 6-12 Shape epicoele and annular cavity of resorption.Salt water cavity is connected to annular cavity of resorption by the first check valve.The entrance of first check valve is towards salt water Chamber.It is intracavitary in annular to be provided with first annular piston 6-13.It is intracavitary under annular to be provided with the second annular piston 6-14.
Gas outlet and lower gas outlet are offered on the lateral wall of Multi-layer technology pipe 6-8.On Multi-layer technology pipe 6-8 lateral wall Position corresponding with annular cavity of resorption bottom offers lower inlet.On Multi-layer technology pipe 6-8 lateral wall with annular epicoele bottom pair The position answered offers inlet.Lower liquid outlet and upper liquid outlet are offered on the bottom end end face of Multi-layer technology pipe 6-8.Above go out The distance of liquid mouth and lower liquid outlet to Multi-layer technology pipe axis is all larger than the radius of annular cavity of resorption.Lower inlet and lower liquid outlet are equal It is connected to the bottom of annular cavity of resorption.Upper inlet and upper liquid outlet are connected to the bottom of annular epicoele.Upper gas outlet and annular The top of epicoele is connected to.Lower gas outlet is connected to the top of annular cavity of resorption.Third check valve is fixed in lower inlet.Third list It is intracavitary under to the outlet of valve direction annular.The 4th check valve is fixed in lower liquid outlet.The entrance direction annular of 4th check valve Under it is intracavitary.The 5th check valve is fixed in upper inlet.The outlet of 5th check valve is upper intracavitary towards annular.It is solid in upper liquid outlet Surely there is the 6th check valve.The entrance of 6th check valve is upper intracavitary towards annular.First annular piston 6-13 and two first pull rods The bottom end of 6-15 is fixed.The bottom end of second annular piston 6-14 and two second pull rods are fixed.Two first pull rod 6-15 and two The top of the second pull rod of root is respectively and fixedly provided with cross bar.Cross bar on two first pull rod 6-15, which is respectively clamped on corresponding, drives sliding block group The kelly slot of kelly protrusion 6-10 on interior two drawing liquid sliding blocks 6-9.Cross bar on two second pull rods is respectively clamped into corresponding lower drive In movable slider group on two drawing liquid sliding block 6-9 kelly protrusion 6-10 kelly slot.
Three layering collector 6-2 points are layered collector, the first blood donor layering collector and the second blood supply for receptor Person is layered collector.Being layered the Multi-layer technology pipe 6-8 that collector is connect with receptor is receptor's Multi-layer technology pipe.It is supplied with first The Multi-layer technology pipe 6-8 that blood person is layered collector connection is first blood donor's Multi-layer technology pipe.It is layered and acquires with the second blood donor The Multi-layer technology pipe 6-8 of device connection is second blood donor's Multi-layer technology pipe.
As shown in Fig. 1,2 and 6, agglomerate amine mediator agents adding tube 6-3 in offer be vertically arranged and mutually it is independent low Ionic medium channel, cohesion amine aqueous solution channel and suspension passage.Low ionic medium channel, cohesion amine aqueous solution channel, suspension The bottom end in channel and the entrance of three the 7th check valves are respectively communicated with, top and be provided with layering collector 6-2 lateral surface top Low ionic medium entrance, cohesion amine aqueous solution entrance, suspension inlet be respectively communicated with.Three the 7th check valves are arranged at cohesion The bottom end end face of amine mediator agents adding tube 6-3, and outlet is in communication with the outside.Low ionic medium channel, cohesion amine aqueous solution are logical It is provided in road and suspension passage and propels component.Propelling component includes propelling electromagnet 6-16, propelling bar 6-17, propel bullet Spring 6-18, cohesion amine piston 6-6 and second one-way valve 6-7.It propels bar 6-17 and propels electromagnet 6-16 and constitute sliding pair.It propels Spring 6-18 is nested on propelling bar 6-17, and both ends are fixed respectively with propelling bar 6-17, propel electromagnet 6-16.Propel bar 6- 17 bottom end, which passes through, propels electromagnet 6-16, and fixes with cohesion amine piston 6-6.The top of cohesion amine piston 6-6, which is embedded with, propels Iron block.Three electromagnet 6-16 that propel propelled in component are separately fixed at low ionic medium channel, cohesion amine aqueous solution channel, hang The top in supernatant liquid channel.Three cohesion amine piston 6-6 propelled in component and low ionic medium channel, cohesion amine aqueous solution channel, Suspension passage respectively constitutes sliding pair.Low ionic medium entrance, cohesion amine aqueous solution entrance are respectively and fixedly provided with the on suspension inlet Two check valve 6-7.It is logical that the entrance of second one-way valve 6-7 is respectively facing low ionic medium channel, cohesion amine aqueous solution channel, suspension In road.It propels component for three and is respectively higher than low ionic medium entrance, cohesion amine aqueous solution entrance, suspension inlet (i.e. three cohesions Amine piston 6-6 is located at low ionic medium entrance, cohesion amine aqueous solution entrance, suspension inlet and adds far from cohesion amine mediator agents Add the side of the bottom end pipe 6-3 end face).Agglomerating setting on amine mediator agents adding tube 6-3, there are three the second feed liquor buttons.Three Two feed liquor buttons control three power on/off for propelling electromagnet 6-16 respectively.
It agglomerates the low ionic medium entrance on amine mediator agents adding tube 6-3 lateral surface top, cohesion amine aqueous solution entrance, suspend Liquid entrance and the inner cavity of low ionic medium Storage Box 8, cohesion amine aqueous solution Storage Box 9, suspension Storage Box 10 pass through hose respectively Connection.Due to the 7th check valve only export but no import, second one-way valve 6-7 only import but no export, therefore pass through lifting cohesion amine piston 6- repeatedly 6, can constantly be sucked out low ionic medium Storage Box 8, cohesion amine aqueous solution Storage Box 9, the reagent in suspension Storage Box 10 and from Corresponding 7th check valve projects.
Serum channel is offered in serum adding tube 6-4.The bottom end in serum channel and the bottom end end face of layering collector 6-2 Connection, top is connected to the serum entrance for being provided with serum adding tube 6-4 lateral surface top.The blood of two serum adding tube 6-4 The liquid outlet of clear entrance and two the second micropumps is respectively communicated with.The liquid inlet and the first serum the storage box of two the second micropumps 4, the inner cavity of the second serum the storage box is respectively communicated with.Third feed liquor button is provided on serum adding tube 6-4.Third feed liquor button For controlling the starting or closing of corresponding first micropump.The corresponding serum adding tube 6-4 of first serum the storage box 4 is first Serum adding tube.The corresponding serum adding tube 6-4 of second serum the storage box is the second serum adding tube.
A kind of cross matching method of cross matching instrument is specific as follows:
Step 1: receptor's blood after centrifugation layering is packed into the first test tube to be checked.And take out the first test tube, the Two test tubes, third test tube, the 4th test tube, the 5th test tube and the 6th test tube.
Step 2: taking out receptor is layered collector 6-2, and receptor's Multi-layer technology pipe is inserted into the first test tube to be checked It is interior.
Step 3: forward direction, which stirs lower driving drawing liquid sliding block group, corresponds to drawing liquid switch, receptor is layered in collector 6-2 lower drive Dynamic drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong forward current, so that the second annular in receptor's Multi-layer technology pipe is living 6-14 is filled in rise.The haemocyte of sucking receptor's blood in the annular cavity of resorption of receptor's Multi-layer technology pipe.
Step 4: driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, receptor's Multi-layer technology pipe is inserted into In first test tube.
Step 5: reversely stirring lower driving drawing liquid sliding block group corresponds to drawing liquid switch, receptor is layered in collector 6-2 lower drive Dynamic drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong reverse current, so that the second annular in receptor's Multi-layer technology pipe is living Fill in 6-14 decline.The haemocyte of intracavitary receptor's blood is partially injected to the first test under the annular of receptor's Multi-layer technology pipe In test tube.
Step 6: lower driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, receptor's Multi-layer technology pipe is inserted Enter in the second test tube.
Step 7: reversely stirring lower driving drawing liquid sliding block group corresponds to drawing liquid switch, receptor is layered in collector 6-2 lower drive Dynamic drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong reverse current, so that the second annular in receptor's Multi-layer technology pipe is living Fill in 6-14 decline.The haemocyte of intracavitary receptor's blood is radiated into the second test tube under the annular of receptor's Multi-layer technology pipe In.
Step 8: receptor's layering collector 6-2 is put back to corresponding mounting hole.Take out the first serum adding tube, and by The entrance of the first test tube of bottom end face of one serum adding tube.
Step 9: pressing the third feed liquor button in the first serum adding tube.First serum the storage box is corresponding second micro- Type pump startup, the A serum in the first serum the storage box are dropped into the first test tube.
Step 10: unclamping the third feed liquor button in the first serum adding tube, the first serum adding tube is put back into corresponding peace Fill hole.Take out the second serum adding tube, and by the entrance of the second test tube of bottom end face of the second serum adding tube.
Step 11: pressing the third feed liquor button in the second serum adding tube.Second serum the storage box corresponding second Miniature pump startup, the B serum in the second serum the storage box are dropped into the second test tube.
Step 12: unclamping the third feed liquor button in the second serum adding tube, the second serum adding tube is put back into correspondence Mounting hole.
Step 13: doctor judges the blood of receptor according to the agglutination situation in the first test tube and the second test tube Type.
Step 14: taking out two donor bloods identical with recipient blood group types and being centrifuged layering.After centrifugation layering First donor blood be packed into the second test tube to be checked.It is to be checked that second donor blood after centrifugation layering is packed into third Test tube.
Step 15: taking out receptor is layered collector, and receptor's Multi-layer technology pipe is inserted into the first test tube to be checked. Simultaneously forward direction stir driving drawing liquid sliding block group correspond to drawing liquid switch and lower driving drawing liquid sliding block group correspond to drawing liquid switch, receptor It is layered the logical forward current of four drawing liquid electromagnet in collector, so that the first annular piston 6- in receptor's Multi-layer technology pipe 13 and second annular piston 6-14 rise.The haemocyte of sucking receptor, ring in the annular cavity of resorption of receptor's Multi-layer technology pipe The blood plasma of sucking receptor in shape epicoele.
Step 16: upper driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, the first feed liquor button is pressed.By Blood person is layered the corresponding first miniature pump startup of collector, and the physiological saline in physiological saline Storage Box enters receptor's layering In extraction tube, and annular cavity of resorption is entered by the first check valve, so that intracavitary haemocyte is diluted ten times under annular.
Step 17: lower driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, by receptor's Multi-layer technology pipe Bottom end face third test tube entrance, reversely stir lower driving drawing liquid sliding block group correspond to drawing liquid switch, receptor layering It is lower in collector 6-2 to drive the logical reverse current of the corresponding two drawing liquid electromagnet of drawing liquid sliding block group, so that receptor's layering mentions The second annular piston 6-14 in pipe is taken to decline.Haemocyte quilt after the annular cavity of resorption inner part dilution of receptor's Multi-layer technology pipe It injects in third test tube.
Step 18: lower driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, by receptor's Multi-layer technology pipe The 4th test tube of bottom end face entrance.It reversely stirs driving drawing liquid sliding block group and corresponds to drawing liquid switch, receptor's layering It is upper in collector to drive the logical reverse current of the corresponding two drawing liquid electromagnet of drawing liquid sliding block group, so that receptor's Multi-layer technology pipe Interior first annular piston 6-13 decline.Receptor's Multi-layer technology pipe ring shape epicoele inner part blood plasma is radiated into the 4th test examination Guan Zhong.
Step 19: upper driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, by receptor's Multi-layer technology pipe The 5th test tube of bottom end face entrance.It reversely stirs lower driving drawing liquid sliding block group and corresponds to drawing liquid switch, receptor's layering It is lower in collector 6-2 to drive the logical reverse current of the corresponding two drawing liquid electromagnet of drawing liquid sliding block group, so that receptor's layering mentions The second annular piston 6-14 in pipe is taken to decline.Haemocyte quilt under the annular of receptor's Multi-layer technology pipe after intracavitary remaining dilution It injects in the 5th test tube.
Step 20: lower driving drawing liquid sliding block group, which is corresponded to drawing liquid switch, returns back to middle position, by receptor's Multi-layer technology pipe The 6th test tube of bottom end face entrance.It reversely stirs driving drawing liquid sliding block group and corresponds to drawing liquid switch, receptor's layering It is upper in collector to drive the logical reverse current of the corresponding two drawing liquid electromagnet of drawing liquid sliding block group, so that receptor's Multi-layer technology pipe Interior first annular piston 6-13 decline.Intracavitary residue blood plasma is radiated into the 6th test examination in receptor's Multi-layer technology pipe ring shape Guan Zhong.
The upper driving drawing liquid sliding block group that receptor is layered collector correspond to drawing liquid and switchs and returns back to by step 2 11 Receptor's layering collector 6-2 is put back to corresponding mounting hole by position.It takes out the first blood donor and is layered collector, and by the first blood supply Person's Multi-layer technology pipe is inserted into the second test tube to be checked.
Step 2 12, simultaneously forward direction stir driving drawing liquid sliding block group and correspond to drawing liquid switch and lower driving drawing liquid sliding block group Corresponding drawing liquid switch, the first blood donor is layered the logical forward current of four drawing liquid electromagnet in collector, so that the first blood donor First annular piston 6-13 and the second annular piston 6-14 in Multi-layer technology pipe rise.First blood donor's Multi-layer technology pipe The haemocyte of the first blood donor of sucking in annular cavity of resorption, the blood plasma of annular epicoele the first blood donor of interior sucking.
Step 2 13, upper driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, press the first feed liquor button. First blood donor is layered the corresponding first miniature pump startup of collector, and the physiological saline in physiological saline Storage Box enters first In blood donor's Multi-layer technology pipe, and annular cavity of resorption is entered by the first check valve, so that intracavitary haemocyte is diluted ten under annular Times.
Step 2 14, lower driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, by the first blood donor be layered The entrance of the bottom end face third test tube of extraction tube, reversely stir driving drawing liquid sliding block group correspond to drawing liquid switch, first Blood donor is layered upper driving drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong reverse current in collector, so that the first blood supply First annular piston 6-13 decline in person's Multi-layer technology pipe.Intracavitary blood plasma is emitted in first blood donor's Multi-layer technology pipe ring shape Into third test tube.
Step 2 15, by the first blood donor be layered collector upper driving drawing liquid sliding block group correspond to drawing liquid switch return back to Middle position, by the entrance of the 4th test tube of bottom end face of first blood donor's Multi-layer technology pipe.It is sliding reversely to stir lower driving drawing liquid Block group corresponds to drawing liquid switch, and the first blood donor is layered lower driving drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong in collector Reverse current, so that the second annular piston 6-14 in first blood donor's Multi-layer technology pipe declines.First blood donor's Multi-layer technology Haemocyte under the annular of pipe after intracavitary dilution is radiated into the 4th test tube.
Step 2 16, lower driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, by the first blood donor be layered Collector puts back to corresponding mounting hole.It takes out the second blood donor and is layered collector, and the second blood donor is layered collector insertion the In three test tubes to be checked.
Simultaneously forward direction stir driving drawing liquid sliding block group correspond to drawing liquid switch and lower driving drawing liquid sliding block group correspond to drawing liquid and open It closes, the second blood donor is layered the logical forward current of four drawing liquid electromagnet in collector, so that second blood donor's Multi-layer technology pipe Interior first annular piston 6-13 and the second annular piston 6-14 rises.It is intracavitary under the annular of second blood donor's Multi-layer technology pipe The haemocyte of the second blood donor is sucked, the blood plasma of the second blood donor of sucking in annular epicoele.
Step 2 17, upper driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, press the first feed liquor button. Second blood donor is layered the corresponding first miniature pump startup of collector, and the physiological saline in physiological saline Storage Box enters second In blood donor's Multi-layer technology pipe, and annular cavity of resorption is entered by the first check valve, so that intracavitary haemocyte is diluted ten under annular Times.
Step 2 18, lower driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, by the second blood donor be layered The entrance of the 5th test tube of bottom end face of extraction tube, reversely stir driving drawing liquid sliding block group correspond to drawing liquid switch, second Blood donor is layered upper driving drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong reverse current in collector, so that the second blood supply First annular piston 6-13 decline in person's Multi-layer technology pipe.Intracavitary blood plasma is emitted in second blood donor's Multi-layer technology pipe ring shape Into the 5th test tube.
Step 2 19, upper driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, by the second blood donor be layered The entrance of the 6th test tube of bottom end face of extraction tube.Reversely stir lower driving drawing liquid sliding block group correspond to drawing liquid switch, second Blood donor is layered lower driving drawing liquid sliding block group corresponding two drawing liquid electromagnetism Tie Tong reverse current in collector, so that the second blood supply The second annular piston 6-14 decline in person's Multi-layer technology pipe.Under the annular of second blood donor's Multi-layer technology pipe after intracavitary dilution Haemocyte is radiated into the 6th test tube.
Step 3 ten, lower driving drawing liquid sliding block group is corresponded to drawing liquid switch return back to middle position, by the second blood donor layering adopt Storage puts back to corresponding mounting hole.Take out cohesion amine mediator agents adding tube 6-3.N=3,4,5,6, successively execute step 3 11 With 32.
Step 3 11, will agglomerate amine mediator agents adding tube 6-3 the n-th test tube of bottom end face entrance, press The corresponding second feed liquor button in low ionic medium channel.Electromagnet 6-16 energization is propelled in low ionic medium channel, so that cohesion Low ionic medium in amine mediator agents adding tube 6-3 instills the n-th test tube.
Step 3 12 shakes up liquid in the n-th test tube.
Step 3 13, n=3,4,5,6, successively execute step 3 14 and 35.
Step 3 14, will agglomerate amine mediator agents adding tube 6-3 the n-th test tube of bottom end face entrance, press Agglomerate the corresponding second feed liquor button in amine aqueous solution channel.Electromagnet 6-16 energization is propelled in cohesion amine aqueous solution channel, so that solidifying Cohesion amine aqueous solution in polyamine mediator agents adding tube 6-3 instills the n-th test tube.
Step 3 15 shakes up liquid in the n-th test tube.
Third test tube, the 4th test tube, the 5th test tube and the 6th test tube are put by step 3 16 Centrifuge carries out the centrifugation of 3000 turns/min.After centrifugation two minutes, third test tube, the 4th test tube, the 5th examination are taken out Test test tube and the 6th test tube.
Step 3 17, doctor observe third test tube, the 4th test tube, the 5th test tube and the 6th test examination Whether pipe occurs agglutinating reaction.38 are entered step if agglutinating reaction occurs, (illustrates to test out if agglutinating reaction does not occur Now make mistakes), then three Multi-layer technology pipes are replaced, and execute since step 14 again.
Step 3 18, n=3,4,5,6, successively execute step 3 19 and 40.
Step 3 19, will agglomerate amine mediator agents adding tube 6-3 the n-th test tube of bottom end face entrance, press The corresponding second feed liquor button of suspension passage.Electromagnet 6-16 energization is propelled in suspension passage, so that cohesion amine medium Suspension in reagent adding tube 6-3 instills the n-th test tube.
Step 4 ten shakes up liquid in the n-th test tube.
Step 4 11, doctor observe third test tube, the 4th test tube, the 5th test tube and the 6th test examination Pipe, judges whether receptor's blood and the blood of two blood donors cooperate.

Claims (4)

1. a kind of cross matching instrument, including support frame, reagent draw addition mechanism, the first serum the storage box, the storage of the second serum Box, physiological saline Storage Box, low ionic medium Storage Box, cohesion amine aqueous solution Storage Box and suspension Storage Box;It is characterized in that: The reagent draw addition mechanism include reagent disc, layering collector, Multi-layer technology pipe, cohesion amine mediator agents adding tube and Serum adding tube;The reagent disc and supporting framework is at revolute pair;Physiological saline Storage Box, the first serum the storage box, second Serum the storage box, low ionic medium Storage Box, cohesion amine aqueous solution Storage Box and suspension Storage Box are each attached on reagent disc;Institute The physiological saline Storage Box memory stated is placed with physiological saline;First serum the storage box is provided with A serum;In second serum the storage box Equipped with B serum;Low ionic medium Storage Box is provided with low ionic medium;Cohesion amine aqueous solution Storage Box is provided with cohesion amine aqueous solution; Suspension Storage Box is provided with suspension;
Six mounting holes circumferentially uniformly distributed along reagent disk axis are offered on the bottom surface of the reagent disc;Six mounting holes are blind Hole, and bottom is respectively and fixedly provided with permanent magnetic steel;Agglomerate amine mediator agents adding tube, three layering collectors and two serum adding tubes Top be embedded with Attraction block;
Fluid-through chamber is offered inside the layering collector;The bottom end of fluid-through chamber is connected to the bottom end end face of layering collector, Top is connected to the physiological saline entrance for being provided with layering collector lateral surface top;It is layered on the lateral surface of collector and offers Four sliding slots circumferentially uniformly distributed along itself;The length direction of four sliding slots is along the axis direction setting of layering collector;Four Drawing liquid sliding block and four sliding slots respectively constitute sliding pair;Drawing liquid electromagnet is respectively and fixedly provided at the top of four sliding slots;Drawing liquid sliding block is Permanent magnet;The bottom of four drawing liquid sliding block lateral surfaces is provided with kelly protrusion;The drawing liquid sliding block group that two of them are oppositely arranged At lower driving drawing liquid sliding block group;Drawing liquid sliding block group is driven on the drawing liquid sliding block composition that another two is oppositely arranged;Lower driving drawing liquid is sliding Kelly protrusion in block group on two drawing liquid sliding blocks is aligned on the axis direction of layering collector;In upper driving drawing liquid sliding block group Kelly protrusion on two drawing liquid sliding blocks is aligned on the axis direction of layering collector;Two pumpings in lower driving drawing liquid sliding block group Kelly protrusion in kelly protrusion and upper driving drawing liquid sliding block group on liquid sliding block on two drawing liquid sliding blocks is in layering collector Axis direction is arranged in a staggered manner;Kelly slot is offered in four kelly protrusions;It is layered on the bottom end end face of collector and is fixed with rubber Connection ring;The first feed liquor button and two drawing liquid switches are provided on layering collector;Drawing liquid switch uses three toggle switches;
Physiological saline entrance on three layering collectors passes through hose with the liquid outlet of three the first micropumps respectively and is connected to;Three The liquid inlet of a first micropump is connected to the inner cavity of physiological saline Storage Box;The bottom end of three layering collectors is mounted on Multi-layer technology pipe;The extraction chamber for being internally provided with bottom closing, open-top of Multi-layer technology pipe;Chamber is extracted in Multi-layer technology pipe Top be provided with connection hole;Connection hole aperture is equal to the outer diameter of rubber connection ring;The extraction of Multi-layer technology pipe is intracavitary solid Surely there is Brine Pipe;The Brine Pipe is divided into the salt water cavity inside Brine Pipe and the annular segment outside Brine Pipe for chamber is extracted Chamber;Annular partition plate is fixed in the middle part of annular segment chamber;Annular segment chamber is divided into annular epicoele and ring by annular partition plate Shape cavity of resorption;Salt water cavity is connected to annular cavity of resorption by the first check valve;The entrance of first check valve is towards salt water cavity;Annular epicoele Inside it is provided with first annular piston;It is intracavitary under annular to be provided with the second annular piston;
Gas outlet and lower gas outlet are offered on the lateral wall of the Multi-layer technology pipe;On Multi-layer technology pipe lateral wall with annular The corresponding position in cavity of resorption bottom offers lower inlet;Position corresponding with annular epicoele bottom is opened on Multi-layer technology pipe lateral wall Equipped with upper inlet;Lower liquid outlet and upper liquid outlet are offered on the bottom end end face of Multi-layer technology pipe;Lower inlet and lower liquid out Mouth is connected to the bottom of annular cavity of resorption;Upper inlet and upper liquid outlet are connected to the bottom of annular epicoele;Upper gas outlet with The top of annular epicoele is connected to;Lower gas outlet is connected to the top of annular cavity of resorption;Third check valve is fixed in lower inlet;The It is intracavitary under the outlet direction annular of three check valves;The 4th check valve is fixed in lower liquid outlet;The entrance direction of 4th check valve It is intracavitary under annular;The 5th check valve is fixed in upper inlet;The outlet of 5th check valve is upper intracavitary towards annular;Upper liquid outlet Inside it is fixed with the 6th check valve;The entrance of 6th check valve is upper intracavitary towards annular;First annular piston and two first pull rods Bottom end fix;The bottom end of second annular piston and two second pull rods is fixed;Two first pull rods and two second pull rods Top is respectively and fixedly provided with cross bar;Cross bar on two first pull rods, which is respectively clamped on corresponding, to be driven in sliding block group on two drawing liquid sliding blocks The kelly slot of kelly protrusion;Cross bar on two second pull rods is respectively clamped into corresponding lower driving sliding block group on two drawing liquid sliding blocks The kelly slot of kelly protrusion;
Mutual independent low ionic medium channel, cohesion amine aqueous solution channel and suspension are offered in cohesion amine mediator agents adding tube Liquid channel;The entrance point in low ionic medium channel, cohesion amine aqueous solution channel, the bottom end of suspension passage and three the 7th check valves It is not connected to, top and the low ionic medium entrance, cohesion the amine aqueous solution entrance, suspension that are provided with layering collector lateral surface top Entrance is respectively communicated with;Three the 7th check valves are arranged on the bottom end end face of cohesion amine mediator agents adding tube;Low ion is situated between It is provided in matter channel, cohesion amine aqueous solution channel and suspension passage and propels component;Propelling component includes propelling electromagnet, pushing away It penetrates bar, propel spring, cohesion amine piston and second one-way valve;It propels bar and propels electromagnet and constitute sliding pair;Propel spring pocket It sets on propelling bar, and both ends are fixed respectively with propelling bar, propel electromagnet;The bottom end for propelling bar, which passes through, propels electromagnet, and It is fixed with cohesion amine piston;The top of cohesion amine piston, which is embedded with, propels iron block;It propels in component for three and propels electromagnet difference The top for being fixed on low ionic medium channel, agglomerating amine aqueous solution channel, suspension passage;Three cohesion amine propelled in component are living Plug respectively constitutes sliding pair with low ionic medium channel, cohesion amine aqueous solution channel, suspension passage;Low ionic medium entrance coagulates Second one-way valve is respectively and fixedly provided on polyamine solution inlet and suspension inlet;The entrance of second one-way valve is respectively facing low ion and is situated between Matter channel, cohesion amine aqueous solution channel, in suspension passage;It propels component for three and is respectively higher than low ionic medium entrance, cohesion amine Solution inlet, suspension inlet;Agglomerating setting in amine mediator agents adding tube, there are three the second feed liquor buttons;Agglomerate the examination of amine medium Low ionic medium entrance, cohesion amine aqueous solution entrance, suspension inlet and the low ionic medium on agent adding tube lateral surface top store Box, cohesion amine aqueous solution Storage Box, suspension Storage Box inner cavity respectively pass through hose be connected to;
Serum channel is offered in serum adding tube;The bottom end in serum channel is connected to the bottom end end face of layering collector, top It is connected to the serum entrance for being provided with serum adding tube lateral surface top;The serum entrance of two serum adding tubes and two second The liquid outlet of micropump is respectively communicated with;The liquid inlet and the first serum the storage box, the second serum the storage box of two the second micropumps Inner cavity be respectively communicated with;Third feed liquor button is provided in serum adding tube.
2. a kind of cross matching instrument according to claim 1, it is characterised in that:The support frame include upper mounting ring, Under put ring and support column;The bottom end of three support columns is put ring under and is fixed, and top is fixed with upper mounting ring.
3. a kind of cross matching instrument according to claim 1, it is characterised in that:The Attraction block using magnetic material or Permanent magnet.
4. a kind of cross matching instrument according to claim 1, it is characterised in that:One end of the kelly slot and kelly protrusion Enter rod end end face connection;Kelly protrusion enters rod end end face and the connectivity part of kelly slot is equipped with chamfering;The upper liquid outlet and The distance of lower liquid outlet to Multi-layer technology pipe axis is all larger than the radius of annular cavity of resorption.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110187133A (en) * 2019-04-12 2019-08-30 杭州电子科技大学 A kind of experimental rig for cross matching

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635680A (en) * 1969-09-22 1972-01-18 Technicon Corp Automatic method and apparatus for the sequential typing of blood samples
US4130395A (en) * 1975-08-19 1978-12-19 Beth Israel Medical Center Process and apparatus for detection of specific biological factors by means of osmotic hemolysis
JPS6457170A (en) * 1987-08-27 1989-03-03 Olympus Optical Co Automatic analyzer
EP0895088A2 (en) * 1997-08-01 1999-02-03 Ortho-Clinical Diagnostics, Inc. An automated blood analysis system
CN101865927A (en) * 2009-04-17 2010-10-20 武汉医尔特科技有限公司 Novel full-automatic blood type analyzer
CN203216930U (en) * 2013-05-07 2013-09-25 迟晓云 Novel blood-matching workbench
CN103424563A (en) * 2013-09-05 2013-12-04 苏州长光华医生物医学工程有限公司 Mechanical arm for automatic blood type detector
CN204925140U (en) * 2015-08-26 2015-12-30 江苏中济万泰生物医药有限公司 System of full -automatic blood bank
CN105974147A (en) * 2016-07-01 2016-09-28 江苏克莱斯克生物技术有限公司 Automatic integral serological blood group detector
CN106596992A (en) * 2017-02-15 2017-04-26 山东新华医疗器械股份有限公司 Multi-channel fully automatic blood type analyzer
CN107247154A (en) * 2017-07-31 2017-10-13 刘大基 Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635680A (en) * 1969-09-22 1972-01-18 Technicon Corp Automatic method and apparatus for the sequential typing of blood samples
US4130395A (en) * 1975-08-19 1978-12-19 Beth Israel Medical Center Process and apparatus for detection of specific biological factors by means of osmotic hemolysis
JPS6457170A (en) * 1987-08-27 1989-03-03 Olympus Optical Co Automatic analyzer
EP0895088A2 (en) * 1997-08-01 1999-02-03 Ortho-Clinical Diagnostics, Inc. An automated blood analysis system
CN101865927A (en) * 2009-04-17 2010-10-20 武汉医尔特科技有限公司 Novel full-automatic blood type analyzer
CN203216930U (en) * 2013-05-07 2013-09-25 迟晓云 Novel blood-matching workbench
CN103424563A (en) * 2013-09-05 2013-12-04 苏州长光华医生物医学工程有限公司 Mechanical arm for automatic blood type detector
CN204925140U (en) * 2015-08-26 2015-12-30 江苏中济万泰生物医药有限公司 System of full -automatic blood bank
CN105974147A (en) * 2016-07-01 2016-09-28 江苏克莱斯克生物技术有限公司 Automatic integral serological blood group detector
CN106596992A (en) * 2017-02-15 2017-04-26 山东新华医疗器械股份有限公司 Multi-channel fully automatic blood type analyzer
CN107247154A (en) * 2017-07-31 2017-10-13 刘大基 Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110187133A (en) * 2019-04-12 2019-08-30 杭州电子科技大学 A kind of experimental rig for cross matching
CN110187133B (en) * 2019-04-12 2022-04-01 杭州电子科技大学 Test device for cross matching

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