CN108896778B - Biochemical analyzer detecting system - Google Patents
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- CN108896778B CN108896778B CN201810950672.7A CN201810950672A CN108896778B CN 108896778 B CN108896778 B CN 108896778B CN 201810950672 A CN201810950672 A CN 201810950672A CN 108896778 B CN108896778 B CN 108896778B
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Abstract
The invention relates to the technical field of medical automatic detection equipment, in particular to a detection system of a biochemical analyzer, which comprises the biochemical analyzer and an upper computer, wherein the biochemical analyzer comprises a mechanical arm sample adding device and a rotary sample disc provided with a plurality of clamping positions, and the clamping positions are used for clamping reagent strips; the upper computer is used for storing control parameters of the mechanical arm sample adding device and the rotary sample disc and controlling the biochemical analyzer to acquire data according to a preset arranging flow and the control parameters; the biochemical analyzer is used for collecting data of the plurality of reagent strips and sending the data of the plurality of reagent strips to the upper computer so that the upper computer can store and process the queue data of the plurality of reagent strips. The dry biochemical analyzer can be accurately controlled by the upper computer to carry out multichannel dynamic detection.
Description
Technical Field
The invention relates to the technical field of medical automatic detection equipment, in particular to a detection system of a biochemical analyzer.
Background
In recent years, dry biochemical instruments have been developed rapidly due to the characteristics of rapid and convenient operation, such as reflotron plus type dry biochemical instrument of Roche and 4000ie full-automatic dry biochemical analyzer of FUJIFILM, which adopt dry chemistry methods, and when the instrument is used, a sample is only required to be added on a solid phase carrier dry reagent strip for subsequent determination without a traditional pipeline system.
In clinical practice, one patient often needs to perform several dry biochemical detections, and meanwhile, the number of patients to be detected is huge, and a dry biochemical analyzer adopting multi-channel dynamic detection can simultaneously collect a plurality of reagent strip samples, so that the detection efficiency can be improved, but the control requirement on the dry biochemical multi-channel dynamic detection is higher. How to accurately control the multi-channel dynamic detection of the dry biochemical analyzer is very important.
Disclosure of Invention
The invention aims to provide a detection system of a biochemical analyzer, which can accurately control a dry biochemical analyzer to carry out multichannel dynamic detection.
The invention provides a biochemical analyzer detection system which comprises a biochemical analyzer and an upper computer, wherein the biochemical analyzer comprises a mechanical arm sample adding device and a rotary sample disc provided with a plurality of clamping positions, and the clamping positions are used for clamping reagent strips;
the upper computer is used for storing control parameters of the mechanical arm sample adding device and the rotary sample disc and controlling the biochemical analyzer to carry out data acquisition according to a preset arranging flow and the control parameters;
the biochemical analyzer is used for collecting a plurality of reagent strip data and sending the plurality of reagent strip data to the upper computer so that the upper computer can store and process the queue data of the plurality of reagent strip data.
Further, the upper computer stores the control parameters in a file by adopting a synchronous writing instruction, and stores a plurality of detection results obtained by processing a plurality of pieces of reagent strip data in a database.
Furthermore, biochemical analyzer is including setting up the correlation opto-coupler on the rotatory sample disc, the correlation opto-coupler is used for detecting whether block is equipped with the reagent strip on the screens.
Furthermore, the biochemical analyzer also comprises a multi-grid optical coupler and an out-of-step detection optical coupler which are arranged on the rotary sample disc;
when the optical coupler of the multi-grid detects the reagent strip on the corresponding card position, the biochemical analyzer collects the data of the reagent strip on the corresponding card position;
the step-out detection optical coupler is used for detecting whether the rotary sample disc is step-out or not.
Further, biochemical analyzer still including setting up rotatory sample disc on the opto-coupler that resets, the opto-coupler that resets is used for making rotatory sample disc resets.
Further, the biochemical analyzer is also used for sending detection data of the correlation optical coupler, the number grid optical coupler, the step-out detection optical coupler and the reset optical coupler to the upper computer; and the upper computer controls the biochemical analyzer to acquire data according to the detection data.
Furthermore, the biochemical analyzer comprises a processing module and a multi-channel acquisition module connected with the processing module;
the processing module controls the multichannel acquisition module to acquire a plurality of data of the reagent strips on the clamping positions on the rotary sample disc and sends the acquired data to the upper computer.
Furthermore, the biochemical analyzer also comprises a motor driving module and a motor, wherein the motor is connected with the rotary sample disc;
the motor driving module drives the motor to drive the rotary sample disc to rotate and the access control of the clamping position.
Further, the biochemical analyzer further comprises a temperature control device connected with the upper computer, and the temperature control device is used for controlling the internal temperature of the reaction disc of the rotary sample disc.
Furthermore, the upper computer is also used for controlling the mechanical arm sample adding device in a time slice rotation mode and controlling the rotary sample disc to work through the detection device;
the upper computer divides the time slice into two time stamps for management, wherein one time stamp is the time stamp of the mechanical arm sample adding device, and the other time stamp is the time stamp of the rotary sample disc.
The biochemical analyzer detection system comprises a biochemical analyzer and an upper computer, wherein the biochemical analyzer comprises a mechanical arm sample adding device and a rotary sample disc provided with a plurality of clamping positions, and the clamping positions are used for clamping reagent strips; the upper computer is used for storing control parameters of the mechanical arm sample adding device and the rotary sample disc and controlling the biochemical analyzer to acquire data according to a preset arranging flow and the control parameters; the biochemical analyzer is used for collecting data of the plurality of reagent strips and sending the data of the plurality of reagent strips to the upper computer so that the upper computer can store and process the queue data of the plurality of reagent strips. The dry biochemical analyzer can be accurately controlled by the upper computer to carry out multichannel dynamic detection.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic structural diagram of a biochemical analyzer according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a rotating sample disc and a pushing mechanism of a biochemical analyzer according to an embodiment of the present invention;
FIG. 3 is a schematic view of a detection system of a biochemical analyzer according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a pushing mechanism of a biochemical analyzer according to an embodiment of the present invention;
fig. 5 is a schematic structural diagram of an execution part on a pushing mechanism of a biochemical analyzer according to an embodiment of the present invention.
Icon: 100-a workbench; 200-rotating the sample disc; 300-a detection mechanism; 400-number lattice optical couplers; 500-step out detection optical coupler; 600-a reset optocoupler; 700-a pushing mechanism; 800-a positioning mechanism; 900-mechanical arm sample adding device; 1000-biochemical analyzer; 2000-upper computer; 210-clamping; 710-a drive section; 720-a guide; 730-an execution part; 740-a transmission part; 731-sliding block; 732-a return spring; 733-an execution plate; 734-an extension plate; 735-a locating plate; 736-a card receiving plate; 7340 card slot.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
FIG. 1 is a schematic structural diagram of a biochemical analyzer according to an embodiment of the present invention; fig. 2 is a schematic structural diagram of a rotating sample disk 200 and a pushing mechanism of a biochemical analyzer according to an embodiment of the present invention.
As shown in fig. 1 and 2, the biochemical analyzer includes: a table 100, a rotary sample disk 200; the rotary sample disc 200 is rotatably disposed on the working platform 100, a plurality of clamping positions 210 for clamping reagent strips are disposed on the rotary sample disc 200, the number of the clamping positions 210 may be 12, 16 or more, the number of the clamping positions 210 in this embodiment is 16, and the number of the clamping positions can be adjusted according to specific use conditions.
The detection mechanism 300 is disposed on the working platform 100, one end of the detection mechanism 300 is disposed on the rotary sample disk 200, and the detection mechanism 300 is used for collecting data on the reagent strip disposed on the card 210. Wherein the detection mechanism 300 is an optical path.
The biochemical analyzer is provided with a detection mechanism 300 above the rotary sample disc 200, and the rotary sample disc 200 can rotate, so that the detection can be continuously performed on the reagent strips in the screens 210 on the rotary sample disc 200. The biochemical analyzer of this embodiment has a plurality of screens on the rotating style disc based on dynamic multichannel detection, as long as the disc rotates the round, can be with the multiunit testing data of a plurality of reagent strips that a plurality of screens correspond to the improvement efficiency that detects.
As shown in fig. 3, the detection system of the biochemical analyzer provided in this embodiment includes the biochemical analyzer 1000 and the upper computer 2000; the biochemical analyzer 1000 further comprises a mechanical arm sample adding device, and sample adding operation is performed through the mechanical arm sample adding device;
the upper computer 2000 is used for storing control parameters of the mechanical arm sample adding device and the rotary sample disc and controlling the biochemical analyzer to collect data according to a preset arranging flow and the control parameters;
the biochemical analyzer 1000 is configured to collect a plurality of reagent strip data and send the plurality of reagent strip data to the upper computer 2000, so that the upper computer 2000 performs queue data storage and processing on the plurality of reagent strip data. The upper computer 2000 performs queue data storage and processing on the collected multiple groups of data, and data accuracy is ensured.
Specifically, the host computer can adopt the tall and erect host computer of ann, stores the core data to the biochemical analysis appearance through tall and erect file, Sharepreference mechanism and database storage, including control parameter and measuring result data etc. storage such as arm position, various sensor settings. The upper computer 2000 can accurately control the biochemical analyzer 1000 to perform multi-channel dynamic detection.
The preset arranging flow is set by the upper computer 2000 according to the detection items of the biochemical analyzer 1000, each item has fixed measurement time, fixed sample type, sample adding amount and the like which are known, tasks can be arranged according to specific detection items, when the tasks are operated, software schedules different modules according to a time slice principle to cooperate, then data are sampled, and the data are processed into concentration, such as Ng/L.
The upper computer 2000 stores the control parameters in a file by using a synchronous write instruction, and stores a plurality of detection results obtained by processing a plurality of pieces of reagent strip data in a database.
Specifically, the android shared preference storage technology is adopted to store the control parameters into a file, and a synchronous writing instruction is adopted during storage to ensure that the control parameters are written in one hundred percent. Data loss caused by power failure can be avoided, and the information is protected by using duplicate files, so that the reliability of the data is ensured, and the safety and the stability of the biochemical analyzer 1000 are improved. And (3) processing the dynamically collected data of the plurality of reagent strips through software to obtain a detection result (converted into required concentration information), and storing the concentration information and the related information of a detector into a memory in an android SQlite database storage mode.
On the basis of the above embodiment, further, the biochemical analyzer 1000 includes a correlation optical coupler disposed on the rotary sample disk 200, and the correlation optical coupler is used for detecting whether a reagent strip is clamped on the clamping position. The opposite-emitting optical coupler is fixedly arranged on the workbench 100, one end of the symmetrical optical coupler is arranged above the rotary sample disc 200, and the other end of the opposite-emitting optical coupler is arranged below the rotary sample disc 200.
In this embodiment, the fixed setting of correlation opto-coupler, when rotatory sample disc 200 rotated, screens 210 passed through the correlation opto-coupler, and whether there is the reagent strip on the correlation opto-coupler can detecting screens 210, and when every screens 210 installation reagent strip, rotatory sample disc 200 all can rotate moreover to make screens 210 of installation reagent strip pass through the correlation opto-coupler, thereby whether the installation of detection reagent strip succeeds.
On the basis of the above embodiment, further, the counter-emission optical coupler further comprises a number-grid optical coupler and a step-out detection optical coupler which are arranged on the rotary sample disc 200;
the number-grid optical coupler 400 and the step-out detection optical coupler 500 are both arranged on the workbench 100, the number-grid optical coupler 400 and the step-out detection optical coupler 500 are both arranged at the bottom end of the rotary sample disc 200, and when the number-grid optical coupler 400 detects a reagent strip on one of the screens 210, the correlation optical coupler collects data of the reagent strip on the screen 210 through the detection mechanism 300;
the step-out detection optocoupler 500 is used for detecting whether the rotary sample disc 200 is step-out.
In this embodiment, number check opto-coupler 400 and step-out detection opto-coupler 500 set up on same mount pad, number check opto-coupler 400 and detection mechanism 300 synchronous working, when having the reagent strip on a screens 210 that number check opto-coupler 400 detected, detection mechanism 300 detects a screens 210, and the several opto-coupler senses the time the same with detection mechanism 300 detects the opto-coupler, and then guarantee detection mechanism 300 can be with the whole detections of screens 210 on the rotatory sample disc 200, in order to improve the precision of whole device. Simultaneously the out-of-step detection optocoupler 500 can detect out the out-of-step condition of the rotary sample disc 200 so as to adjust a driving mechanism for driving the rotary sample disc 200 in a follow-up manner.
On the basis of the above embodiment, further, the biochemical analyzer 1000 further includes a reset optical coupler 600, the reset optical coupler 600 is disposed on the workbench 100 near one side of the step-out detection optical coupler 500, and the reset optical coupler 600 is used for resetting the rotary sample disc 200.
In this embodiment, be provided with the opto-coupler 600 that resets on workstation 100, the opto-coupler 600 that resets can make and detect whether rotatory sample disc 200 resets accurately to the accurate degree of guarantee rotatory sample disc 200 and detection mechanism 300 next work.
Further, the biochemical analyzer 1000 is further configured to send detection data of the correlation optical coupler, the number-grid optical coupler, the step-out detection optical coupler, and the reset optical coupler to the upper computer 2000; the upper computer 2000 controls the biochemical analyzer 1000 to collect data according to the detection data.
The biochemical analyzer detecting system of this embodiment can detect a plurality of screens simultaneously, for solving the unusual problem of dynamic data acquisition in-process business turn over card, sets up the correlation opto-coupler on rotatory sample disc 200 for whether the calibration business turn over card is successful. The steps of the card-feeding process of the rotary sample disc 200 are as follows: firstly, resetting the rotary sample disc 200, and the resetting optocoupler 600 works, so that the calibration resetting is successful; rotating the sample disc 200 for one circle (during which, the out-of-step detection optocoupler 500 and the digital grid optocoupler 400 are started for detection), and recording whether a reagent card exists according to the state of the corresponding optocoupler of different screens (the state 1 of the corresponding optocoupler represents that a card exists in the screen, and the state 0 represents that no card exists); automatically withdrawing all cards at the positions with the cards from the reaction disc; the upper computer 2000 issues a task, card feeding is started, one card is fed in at a time, after the card feeding, the disc is rotated, and whether the card feeding is successful is confirmed by using the correlation optical coupler; after success, if the sample is successfully transferred to the sample adding position, waiting for the sample adding treatment of the mechanical arm sample adding device 900; after the sample is loaded by the mechanical arm sample loading device 900, the state of the corresponding clamping position is changed. And the corresponding card position starts to enter a reaction waiting state, a group of data is detected at preset time intervals and put into a data queue, and when the reaction time is up, the detection data for multiple times is uploaded to the upper computer 2000, and the detection data is stored and analyzed, and the concentration is calculated.
In order to solve the data storage problem, the upper computer 2000 stores the corresponding queue data according to the position of the position (position of position 1-16), the data is obtained from the motor control board of the biochemical analyzer 1000 by the CAN communication mode, and the motor control board realizes the control of the disc, the card entering and exiting, the motor and the real-time acquisition of the multi-channel data. In the data storage process, in order to prevent that data storage position and actual position are different, need protect and inspect data, the protection adopts number check and step-out detection mode, the next quick-witted data acquisition in-process, before once gathering (25s time slice) at every turn, all can reset to mechanical O point, the opto-coupler 600 work that resets, and the code wheel step-out detects normally (the code wheel has 2 opto-couplers, one is the number check opto-coupler 400 of location screens, one is the step-out detection opto-coupler 500 that detects whether the disc is step-out, the use of cooperation correlation opto-coupler, ensure that the information of screens can not be wrong). Then, a dynamic detection instruction is started, and in the dynamic detection process, data collection is carried out on the reagent with the card and the effective reagent according to the state of the card clamping on the disc, and the data are stored in an upper android computer 2000 for data analysis and processing.
The biochemical analyzer 1000 comprises a processing module and a multi-channel acquisition module connected with the processing module; the processing module controls the multi-channel collection module to collect data of the reagent strips on the plurality of screens of the rotary sample disk 200 and sends the collected data to the upper computer 2000. Specifically, the processing module can adopt a single chip microcomputer, such as STM32F303ZET 6; the multi-channel acquisition module can adopt an analog-to-digital converter, such as AD7699, the analog-to-digital converter receives analog signals acquired by the detection mechanism, converts the analog signals into digital signals, then is connected with the single chip microcomputer through a Serial Peripheral Interface (SPI), and sends detection data to the single chip microcomputer, and the single chip microcomputer sends the detection data to the upper computer 2000.
The biochemical analyzer 1000 further comprises a motor driving module and a motor, wherein the motor is connected with the rotary sample disc 200; the motor driving module drives the motor to drive the rotary sample disc 200 to rotate and control the in and out of the clamping position.
Specifically, the motor driving module drives the motor to realize the control of the transmission device, such as: the control of the card, the rotation required by the dynamic collection of the disc, the switch of the reserved temperature control structure, the collection of dynamic data (16-bit 8-channel ADC collection-AD 7699), and the collection of optical coupling signals, such as: reset optical coupler 600, number check optical coupler 400 (location screens), out-of-step detection optical coupler 500 (prevent that the structure from being held owner by the foreign matter, locked rotor etc.) etc..
Further, the biochemical analyzer 1000 further includes a temperature control device connected to the upper computer 2000, and the temperature control device is configured to control an internal temperature of the reaction disk of the rotary sample disk 200. Specifically, the temperature may be detected by a temperature sensor PT1000, the heating wire may be controlled by PWM, and the like.
Further, the biochemical analyzer 1000 samples the reagent strip through the mechanical arm sample-adding device 900, and the upper computer 2000 is connected with the mechanical arm sample-adding device 900; the upper computer 2000 is also used for controlling the mechanical arm sample adding device 900 in a time slice rotation mode and controlling the rotary sample disc 200 to work through the detection device 900;
the slice round robin scheduling refers to each process being assigned a time period, referred to as its slice, that is, the time that the process is allowed to run. If a process is still running at the end of a time slice, the CPU will be deprived and allocated to another process. If the process is blocked or ended before the time slice is ended, the CPU immediately switches. All the scheduler has to do is maintain a list of ready processes, which are moved to the end of the queue when a process has run out of its time slice.
In order to ensure the accuracy of the control time, the software of the upper computer 2000 adopts a time slice rotation mode, the time (for example, 25s) needs to be preset once when the rotary sample disc 200 rotates for one circle and the data processing, state judgment and the like, the time slice rotation scheduling algorithm is strictly followed, the time ticK inside the upper computer 2000 (for example, an android core board) can ensure the accuracy of the time, the error is very small, and the 1 minute error is less than 1 s. For the convenience of scheduling of flow, the management of time slice, host computer 2000 is divided into 2 time stamps with whole time slice and is managed, and one is the time stamp of arm application of sample device 900 (mainly accomplish the application of sample of task sample, the sample, dilutes, the mixing etc.), and one is the rotatory sample disc 200 time stamp (mainly accomplish the card that advances of disc, dynamic verification, play card etc.).
Further, the upper computer 2000 includes a touch screen for data display and man-machine interaction.
On the basis of the above embodiment, further, as shown in fig. 2, the biochemical analyzer 1000 further includes a plurality of pushing mechanisms 700;
the pushing mechanisms 700 are all arranged on the workbench 100, the pushing mechanisms 700 are arranged in a fan shape, and the interval between two adjacent pushing mechanisms 700 is the same as the interval between two adjacent clamping positions 210.
The number of the pushing mechanisms 700 is four.
In this embodiment, the plurality of pushing mechanisms 700 are arranged in a fan shape, so that the pushing mechanisms 700 are adapted to the rotating sample disk 200, and the distance between two adjacent pushing mechanisms 700 is the same as the distance between two adjacent screens 210, so that the plurality of pushing mechanisms 700 can work simultaneously, and the speed of installing reagent strips into the screens 210 is increased.
Fig. 4 is a schematic structural diagram of a pushing mechanism of a biochemical analyzer according to an embodiment of the present invention. As shown in fig. 4, on the basis of the above embodiment, further, the pushing mechanism 700 includes a driving part 710, a guiding part 720, an executing part 730 and a transmission part;
the driving part 710 and the guiding part 720 are arranged on the workbench 100, the executing part 730 is arranged on the guiding part 720, the driving part 710 is connected with the executing part 730 through a transmission part, and the driving part 710 drives the executing part 730 to reciprocate along the extending direction of the guiding part 720 so as to push the reagent strips into the clamping position 210.
Wherein, transmission portion is the belt, and drive division 710 includes the action wheel and follows the driving wheel, and the action wheel sets up respectively at the both ends of guide portion 720 with the both ends of following the driving wheel, and the belt is used for connecting the action wheel with following the driving wheel, and the belt still is connected with execution portion 730, drives execution portion 730 and removes along guide portion 720.
In this embodiment, one end of the guide 720 is close to the edge of the table 100, the other end of the guide 720 extends to the intersection of the table where the center of the rotating sample disk 200 is located, and the actuator 730 can move relative to the guide 720, so that the actuator 730 can push the reagent strip into the card 210.
Fig. 5 is a schematic structural diagram of an execution part on a pushing mechanism of a biochemical analyzer according to an embodiment of the present invention. As shown in fig. 5, on the basis of the above embodiment, further, the actuator 730 includes a slider, a return spring and an actuator plate;
one end of the sliding block is slidably arranged on the guide portion 720, the other end of the sliding block is provided with an extension plate 734, the extension plate 734 is arranged at one end close to the center of the rotary sample disc 200, a through hole and a clamping groove 7340 are arranged on the extension plate 734, the clamping groove 7340 is arranged at one side close to the center of the rotary sample disc 200, the clamping groove 7340 is communicated with the through hole, mounting holes are further arranged at two sides of the extension plate 734, the mounting holes penetrate through the through hole, a bolt penetrates through the mounting holes to install the return spring in the through hole, one end of the return spring is abutted against the side wall of the through hole, and the other end of the return spring;
the execution plate is connected with the return spring, one side of the execution plate extends to the end far away from the clamping groove 7340 and abuts against the extension plate 734, the end far away from the return spring of the execution plate is arranged in an arc shape, and the end in the arc shape of the execution plate is arranged on one side far away from the center of the rotating sample disc 200.
When the through hole of the card slot 7340 is far from the center of the rotary sample disk 200, the end of the actuator plate far from the card slot 7340 extends and abuts against the extension plate 734, so that the reagent strip in the card position 210 can be taken out by the actuator plate during the moving process.
Wherein, the reset spring is a torsion spring.
In this embodiment, an extension plate 734 is disposed on the sliding block, a through hole and a mounting hole are disposed on the extension plate 734, the actuating plate is connected to the return spring, a bolt passes through the mounting hole and the return spring, the return spring is mounted in the through hole, and one end of the return spring is disposed above the locking groove 7340, so that a gap is formed between the service spring and the locking groove 7340, and the other end is disposed on the inner wall near the through hole, because the arc-shaped end of the actuator plate is disposed at the side away from the center of the rotating sample disk 200, the side of the actuator plate extends toward the end away from the clamping groove 7340 and abuts against the extension plate 734, when the actuator plate moves towards the end near the rotating sample disk 200, the actuator plate pushes the strips from the outside into the detents 210, when the execution plate is pushed out, the execution plate can rotate towards one end of the card eraser under the action of an acting force, so that the execution plate is smoothly withdrawn and is reset through the reset spring after being withdrawn.
On the basis of the above embodiment, further, the guiding portion 720 is a sliding rail, one end of the sliding block close to the sliding rail is provided with a sliding groove matched with the sliding rail, one side of the sliding block is provided with a clamping plate 736 matched with the transmission portion, the clamping plate 736 is fixed on the sliding block through a bolt, and the transmission portion is arranged between the clamping plate 736 and the sliding block.
In this embodiment, guide portion 720 is the slide rail, and the bottom of slider is provided with the spout to make the slider can slide on guide portion 720, and still be provided with joint plate 736 in one side of slider, joint plate 736 passes through the bolt and fixes belt and slider, thereby makes the belt drive the slider and removes.
In addition to the above embodiments, a positioning mechanism 800 is further provided at an end of the edge of the table 100 close to the guide 720 and away from the rotary sample disk 200, and the positioning mechanism 800 is electrically connected to the driving unit 710;
the end of the slider remote from the center of the rotating sample disk 200 is provided with a positioning plate 735, and when the positioning plate 735 is used to engage the positioning mechanism 800, the drive portion 710 stops operating.
Further, the locating plate 735 is in an L-shaped configuration, and the locating mechanism 800 is a locating optocoupler which is in a U-shaped configuration.
In this embodiment, a positioning mechanism 800 is further disposed on the worktable 100, the positioning mechanism 800 is a U-shaped positioning optical coupler, a positioning plate 735 is disposed on the slider, the positioning plate 735 is an L-shaped positioning plate, when the positioning plate 735 is matched with the positioning optical coupler, the slider moves to a predetermined position, and at this time, the driving portion 710 stops working, so as to ensure that the position of the slider is relatively stable.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Claims (6)
1. The biochemical analyzer detection system is characterized by comprising a biochemical analyzer and an upper computer, wherein the biochemical analyzer comprises a mechanical arm sample adding device and a rotary sample disc provided with a plurality of clamping positions, and the biochemical analyzer further comprises a detection mechanism, wherein the clamping positions are used for clamping reagent strips;
the upper computer is used for storing control parameters of the mechanical arm sample adding device and the rotary sample disc and controlling the biochemical analyzer to carry out data acquisition according to a preset arranging flow and the control parameters;
the biochemical analyzer is used for acquiring a plurality of reagent strip data and sending the plurality of reagent strip data to the upper computer so that the upper computer can store and process the queue data of the plurality of reagent strip data;
the biochemical analyzer also comprises a check optical coupler and a step-out detection optical coupler which are arranged on the rotary sample disc;
when the optical coupler of the multi-grid detects the reagent strip on the corresponding card position, the biochemical analyzer collects the data of the reagent strip on the corresponding card position;
the step-out detection optocoupler is used for detecting whether the rotary sample disc is step-out;
the biochemical analyzer also comprises a reset optical coupler arranged on the rotary sample disc, and the reset optical coupler is used for resetting the rotary sample disc;
the upper computer is also used for controlling the mechanical arm sample adding device and the rotary sample disc to work in a time slice rotation mode;
the upper computer divides the time slice into two time stamps for management, wherein one time stamp is the time stamp of the mechanical arm sample adding device, and the other time stamp is the time stamp of the rotary sample disc;
the number check opto-coupler with the out-of-step detection opto-coupler sets up on same mount pad, number check opto-coupler with detection mechanism synchronous working works, works as when there is the reagent strip on a screens that number check opto-coupler detected, detection mechanism detects a screens, and number check opto-coupler induction time with detection mechanism detects the time of opto-coupler the same.
2. The biochemical analyzer detection system according to claim 1, wherein the host computer stores the control parameters in a file by using a synchronous writing instruction, and stores a plurality of detection results obtained by processing a plurality of pieces of reagent data in a database.
3. The biochemical analyzer detecting system according to claim 1, wherein the biochemical analyzer is further configured to send detection data of the number-grid optical coupler, the step-out detection optical coupler and the reset optical coupler to the host computer; and the upper computer controls the biochemical analyzer to acquire data according to the detection data.
4. The biochemical analyzer detecting system according to claim 1, wherein the biochemical analyzer includes a processing module and a multi-channel collecting module connected to the processing module;
the processing module controls the multichannel acquisition module to acquire a plurality of data of the reagent strips on the clamping positions on the rotary sample disc and sends the acquired data to the upper computer.
5. The biochemical analyzer detecting system according to claim 4, wherein the biochemical analyzer further comprises a motor driving module and a motor, the motor is connected with the rotating sample disc;
the motor driving module drives the motor to drive the rotary sample disc to rotate and the access control of the clamping position.
6. The biochemical analyzer detecting system according to claim 1, further comprising a temperature control device connected to the upper computer, the temperature control device being configured to control an internal temperature of the reaction disk of the rotating sample disk.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810950672.7A CN108896778B (en) | 2018-08-20 | 2018-08-20 | Biochemical analyzer detecting system |
| PCT/CN2019/091419 WO2020038086A1 (en) | 2018-08-20 | 2019-06-14 | Detection system of biochemical analyzer |
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| CN201810950672.7A CN108896778B (en) | 2018-08-20 | 2018-08-20 | Biochemical analyzer detecting system |
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| CN108896777A (en) * | 2018-08-20 | 2018-11-27 | 基蛋生物科技股份有限公司 | biochemical analyzer |
| CN108896778B (en) * | 2018-08-20 | 2021-02-02 | 基蛋生物科技股份有限公司 | Biochemical analyzer detecting system |
| CN110057808A (en) | 2019-05-27 | 2019-07-26 | 中国人民解放军军事科学院军事医学研究院 | Sample swivel mount and Raman spectrum detector |
| CN110794152A (en) * | 2019-11-04 | 2020-02-14 | 广州科方生物技术股份有限公司 | Reagent card supply mechanism |
| CN110794153A (en) * | 2019-11-04 | 2020-02-14 | 广州科方生物技术股份有限公司 | Automatic dry type fluorescence immunoassay instrument |
| CN111965375B (en) * | 2020-10-21 | 2020-12-29 | 中国科学院苏州生物医学工程技术研究所 | High-throughput sample injection detection scheduling management method based on time slices |
| CN113391058A (en) * | 2021-05-25 | 2021-09-14 | 安徽惠邦生物工程有限公司 | Intelligent upper heating module of dry-type urine analyzer |
| CN114778867A (en) * | 2022-06-13 | 2022-07-22 | 深圳市帝迈生物技术有限公司 | Sample detection device |
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| CN102116771B (en) * | 2010-01-04 | 2013-12-04 | 深圳市亚辉龙生物科技有限公司 | Automatic enzyme-linked immune analysis analyzer |
| CN104597260B (en) * | 2014-11-17 | 2016-10-26 | 基蛋生物科技股份有限公司 | A kind of reagent strip storage and automatic pop-up device |
| CN104535782B (en) * | 2014-12-29 | 2017-01-25 | 基蛋生物科技股份有限公司 | Full-automatic immuno-fluorescence quantitative analysis device and implementation method |
| CN205539016U (en) * | 2016-04-08 | 2016-08-31 | 北京德鲁伊医疗器材有限公司 | Multipurpose medical treatment detector and detecting system |
| CN106153964A (en) * | 2016-08-26 | 2016-11-23 | 梅州康立高科技有限公司 | A kind of electrolyte analyser and the automatically method of sampling |
| CN206038535U (en) * | 2016-08-30 | 2017-03-22 | 广州蓝勃生物科技有限公司 | Automatic dry -type fluorescence detector |
| CN107389959B (en) * | 2017-01-05 | 2020-05-15 | 上海艾瑞德生物科技有限公司 | Turntable positioning device capable of automatically correcting errors and control method thereof |
| CN106950389B (en) * | 2017-04-27 | 2019-07-02 | 珠海科域生物工程股份有限公司 | Dejecta analytical equipment |
| CN107356775B (en) * | 2017-07-03 | 2020-04-14 | 苏州卫宁精密仪器设备有限公司 | Test task planning method for chemiluminescence immunoassay |
| CN108896778B (en) * | 2018-08-20 | 2021-02-02 | 基蛋生物科技股份有限公司 | Biochemical analyzer detecting system |
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| WO2020038086A1 (en) | 2020-02-27 |
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