CN108815327A - The externally applied ointment and preparation method thereof for treating rheumatic waist-leg pain prolapse of lumbar intervertebral disc osteoproliferation - Google Patents
The externally applied ointment and preparation method thereof for treating rheumatic waist-leg pain prolapse of lumbar intervertebral disc osteoproliferation Download PDFInfo
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- CN108815327A CN108815327A CN201811090408.7A CN201811090408A CN108815327A CN 108815327 A CN108815327 A CN 108815327A CN 201811090408 A CN201811090408 A CN 201811090408A CN 108815327 A CN108815327 A CN 108815327A
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Abstract
The present invention relates to a kind of externally applied ointments for treating rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation, and the ointment includes following main component：Rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba, radix cyathulae, ramulus cinnamomi, Herba Epimedii, monkshood, cortex cinnamomi, scorpio, centipede, the larva of a silkworm with batrytis, the root of Dahurain angelica, Eupolyphoge sinensis, spina gleditsiae, lycopodium calvatum, the rhizome of davallia, the root of Chinese clematis, zaocys dhumnade, pangolin.It has preferable therapeutic effect to above-mentioned disease, and easy to use.The present invention also provides the preparation methods of the plaster.
Description
Technical field
The present invention relates to technical field of Chinese medicine, and in particular to a kind of to treat rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and bone
The externally applied ointment and preparation method thereof of matter hyperplasia.
Background technique
With the quickening of the modern life and work rhythm, operating time and working strength are increasing, more and more people's
Body bears huge pressure, to suffer from various diseases.For the people to bend over one's desk working for a long time, it is easy to change
The illnesss such as rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation, and with advancing age, the state of an illness can also aggravate.
Modern medicine thinks the occurrence of this disease, with fatigue, catch cold and humidity is related, such as occupy wetland long, tired backlash wind emits
Rain replaces wet clothing not in time, and lid quilt is not had a cold for summer and autumn sleep.Over time, the tissue degeneratiaon that can make involvement, makes
At touching refractory chronic lumbocrural pain.Rheumatic waist-leg pain is apt to occur in muscle, tendon and vessel, ligament, fat and subcutaneous tissue.Traditional Chinese medicine
Think, rheumatic waist-leg pain is the invasion due to waist-leg portion by wind-cold damp pathogen, and blood vessels numbness is caused to hinder, and movement is unsmooth, to draw
Play the clinical symptoms such as waist-leg portion swelling and pain, apathy.
Lumbar disc herniation is relatively conventional one of illness, is primarily due to lumber ertebral disc each section (nucleus pulposus, fibrous ring
And cartilage plate) especially nucleus pulposus, after having different degrees of degenerative change, under the action of external force factor, the fiber of interverbebral disc
Ring breakage, nucleus pulposus in rear or intraspinal tube, cause adjacent spinal nerve root to be stimulated from rupture place prominent (or abjection)
Or compressing, so that flank pain is generated, a series of clinical symptoms such as side lower limb or double lower limb numbness, pain.Lumber ertebral disc is prominent
Out disease belong to Chinese medicine " Lumbago ", " rheumatism ", " impotence card " scope, it is believed that its cause of disease be wound strain with the damp and hot heresy of affection of exogenous wind-cold
Gas causes battalion to defend imbalance, and qi and blood channels and collaterals are impaired, or since kidney deficiency and liver, exopathogen are taken advantage of a weak point, cause qi and blood stagnation and send out
Disease.
Hyperostosis is mainly in above middle age.It is generally acknowledged that due to having a delicate constitution after the middle age and retrogression；For a long time
It stands or walks and be held in certain posture for a long time, due to the drawing of muscle or avulsion, bleeding, organization of hematoma forms thorn-like
Or the osteoproliferation of lip sample；Spur to soft tissue generate it is mechanical stimulation and wound after soft tissue injury, bleeding, swelling and
It causes.This disease is included in the scope of " heumatism " by traditional Chinese medicine.Think that this disease occurs mostly due to insufficiency of vital energy and blood, caused by liver and kidney deficiency, wind-cold damp pathogen
Intrusion bone network falls servant's sudden strain of a muscle, hurt bone network, so that stagnation of QI-blood, operation is lost freely, not general rule pain.
Above-mentioned disease has a significant impact for the life of modern, and patient is by pain, quality of life decline.And existing skill
Preferable therapeutic effect can be had to above-mentioned disease by lacking in art, and drug easy to use.
Summary of the invention
Being designed to provide for the embodiment of the present invention a kind of treats rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation
Externally applied ointment has preferable therapeutic effect to above-mentioned disease, and easy to use.The embodiment of the invention also provides the cream
The preparation method of medicine.
To achieve the above object, the technical solution of the embodiment of the present invention is that a kind of to treat rheumatic waist-leg pain, Waist disc prominent
Out with the externally applied ointment of osteoproliferation, the ointment includes following ingredients based on parts by weight：Rhizoma homalonemae, pawpaw, bores ground at Radix Angelicae Sinensis
Wind, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba are 15-20 parts each；Radix cyathulae, ramulus cinnamomi, Herba Epimedii are 20-25 parts each；
Monkshood, cortex cinnamomi are 10-15 parts each；Scorpio, centipede are 15-20 parts each；The larva of a silkworm with batrytis, the root of Dahurain angelica are 28-32 parts each；12-18 parts of Eupolyphoge sinensis；Spina gleditsiae
18-22 parts；25-30 parts of lycopodium calvatum；10-15 parts of the rhizome of davallia；8-13 parts of the root of Chinese clematis；18-23 parts of zaocys dhumnade；13-17 parts of pangolin；
2200-2600 parts of sesame oil；1000-1400 parts of yellow lead.
Further, the ointment includes following ingredients based on parts by weight：Rhizoma homalonemae, pawpaw, Chinese hydrangeavine root-bark, does not have Radix Angelicae Sinensis
Medicine, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba are 16-18 parts each；Radix cyathulae, ramulus cinnamomi, Herba Epimedii are 22-24 parts each；Monkshood,
Cortex cinnamomi is 12-14 parts each；Scorpio, centipede are 16-18 parts each；The larva of a silkworm with batrytis, the root of Dahurain angelica are 30-32 parts each；13-16 parts of Eupolyphoge sinensis；Spina gleditsiae 18-21
Part；26-28 parts of lycopodium calvatum；12-14 parts of the rhizome of davallia；9-12 parts of the root of Chinese clematis；18-21 parts of zaocys dhumnade；14-16 parts of pangolin；Sesame oil
2300-2500 parts；1100-1300 parts of yellow lead.
In one embodiment, the ointment includes following ingredients based on parts by weight：Rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, brill
Each 18 parts of ground wind, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Each 22 parts of radix cyathulae, ramulus cinnamomi, Herba Epimedii；It is attached
Son, each 12 parts of cortex cinnamomi；Each 17 parts of scorpio, centipede；Each 30 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；15 parts of Eupolyphoge sinensis；20 parts of spina gleditsiae；28 parts of lycopodium calvatum；
13 parts of the rhizome of davallia；10 parts of the root of Chinese clematis；20 parts of zaocys dhumnade；15 parts of pangolin；2500 parts of sesame oil；1200 parts of yellow lead.
In another embodiment, the ointment includes following ingredients based on parts by weight：Rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw,
Each 16 parts of Chinese hydrangeavine root-bark, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Each 24 parts of radix cyathulae, ramulus cinnamomi, Herba Epimedii；It is attached
Son, each 14 parts of cortex cinnamomi；Each 16 parts of scorpio, centipede；Each 32 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；13 parts of Eupolyphoge sinensis；18 parts of spina gleditsiae；26 parts of lycopodium calvatum；
14 parts of the rhizome of davallia；12 parts of the root of Chinese clematis；20 parts of zaocys dhumnade；16 parts of pangolin；2400 parts of sesame oil；1300 parts of yellow lead.
Wherein, each ingredient and action function are as follows：
Rhizoma homalonemae：For the dry root of aroid rhizoma homalonemae (Homalomena occulta (Lour.) Schott)
Stem.It is bitter, pungent, it is warm-natured.Return liver and kidney channel.The effect of having wind-damp dispelling, strengthening the bone.It is used for treating arthralgia due to cold and dampness, waist and knee crymodynia, muscular constricture fiber crops
Wood, muscles and bones impotence.
Radix Angelicae Sinensis：Alias is dry to return, the Qin which, western Radix Angelicae Sinensis etc., and perennial herb, root can be used as medicine, and be one of most common Chinese medicine.
Property is sweet, pungent, warm.Return liver, the heart, the spleen channel.With benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine, anticancer, anti-ageing anti-old, immune function
Effect.
Pawpaw：For rosaceous plant chaenomeles lagenaria (Chaenomeles speciosa (Sweet) Nakai) drying closely at
Ripe fruit.Summer, two season of autumn fruit it is greenish-yellow when harvest, set and scalded in boiling water to crust canescence, double of vertical profile dries.It is sour, property
Temperature.Return liver, the spleen channel.There is the effect of relaxing tendons and activating collaterals, stomach function regulating dampness elimination.For treating arthritis with fixed pain caused by dampness muscular constricture, waist and knee joints acid weight pain, summer-heat and damp
It vomits and diarrhoea, spasm contraction pain, tinea pedis oedema.
Chinese hydrangeavine root-bark：For saxifragaceae plant Chinese hydrangeavine root-bark (Schizophragmaintegrifolium (Franch.) Oliv.)
Root and stem rattan.It is lightly seasoned, it is cool in nature.Converge to the spleen channel.Relaxing tendons and activating collaterals, expelling wind and activating blood flow.Rheumatic arthralgia is cured mainly, extremities joint is ached.
Myrrh：For olive subject plant Chinese violet tree (Commiphora myrrha Engl.) or Ha Didingshu (Commiphora
Molmol Engl.) dry resin.Acrid flavour, hardship, it is mild-natured.Return heart, liver, the spleen channel.Scattered stasis pain, detumescence and promoting granulation.For thoracic obstruction
Pained, gastral cavity pain, dysmenorrhea menostasis postpartum stasis , abdominal mass and abdominal pain, rheumatic arthralgia, traumatic injury, the illnesss such as carbuncle swells sore control
It treats.
Pheretima：Pheretima is important one of the Chinese medicine in China.Earliest Chinese pharmacology monograph《Sheng Nong's herbal classic》In record
Just there is earthworm in 67 kinds of animal drugs.?《Sheng Nong's herbal classic》Be classified as low-grades, have clearing heat for calming endogenous wind, clearing and activating the channels and collaterals, clearing lung, relieving asthma, clearly
The effect of hot diuresis.High fever, coma, twitch, arthralgia, dyspnea and cough due to lung-heat, oliguria oedema, hypertension are used for after normal frying
Equal diseases.It is main to contain a variety of amino acid.
Semen Cuscutae：For convolvulaceous plant Cuscuta australis (Cuscuta australis R.Br.) or Semen Cuscutae
The dry mature seed of (Cuscuta chinensis Lam.).With tonifying the liver and kidney, astringent sperm contracting urine, miscarriage prevention, improving eyesight, antidiarrheal it
Effect, external application have the effect of disappearing wind nti-freckle.It is usually used in kidney deficiency and liver, soreness and weakness of waist and knees, impotence and seminal emission, enuresis frequent micturition, kidney deficiency tire
Leakage, threatened abortion, blurred vision tinnitus, spleen kidney deficiency are rushed down；Externally treating leucoderma.
Cortex Eucommiae：Its is sweet in flavor, warm-natured.Return liver and kidney channel.Have tonify the liver and kidney, strengthen muscles and bones, the function of coordinating Chong and Conception Vessels, strengthen meridian and miscarriage prevention
Effect.Pain in waist and lower extremities caused by kidney-yang deficiency or aching and limp inability can be treated, born of the same parents' tire caused by liver- qi invasion is not solid, and wet itch of scrotum waits diseases.
Radix Angelicae Pubescentis：For umbelliferae Angelica pubescens (Angelica pubescens Maxim.f.biserrata Shan
Et Yuan) dry root.Acrid flavour, hardship, slightly warm in nature.Return kidney, bladder meridian.Dispelling wind and eliminating dampness, arthritis analgesic.It is used for treating arthralgia due to cold and dampness, waist
Knee pain, few the moon volt wind headache, headache caused by cold and dampness.
Rhizoma Et Radix Notopterygii：Umbelliferae, Rhizoma Et Radix Notopterygii platymiscium, perennial herb.Acrid flavour, hardship, it is warm-natured.Enter bladder, kidney channel.Relieving exterior syndrome and dispelling cold,
Expelling wind and eliminating dampness, analgesic.Anemofrigid cold, wind-cold-dampness arthralgia, item strengthening tendons are anxious, joint ache, geomantic omen edema, skin sore.
Radix Paeoniae Alba：For the dry root of ranunculaceae plant Chinese herbaceous peony (Paeonia tacti lora Pall.).Bitter, acid, property are micro-
It is cold.Return liver, the spleen channel.Nourishing blood for regulating menstruation, astringing YIN to stop sweating, soft liver analgesic, suppressing liver-YANG.For blood deficiency chlorosis, irregular menstruation, spontaneous perspiration,
Night sweat, hypochondriac pain, abdominal pain, four limbs contraction pain, headache and dizziness.
Radix cyathulae：For the dry root of amaranthaceous plant radix cyathulae (Cyathula officinalis Kuan).Sweet in flavor, slight bitter,
It is mild-natured.Return liver and kidney channel.Dispelling stasis of blood and stimulating the menstrual flow, easing joint movement, inducing diuresis for treating strangurtia.For menostasis abdominal mass, placenta retension, injury from falling down, rheumatism
Numbness pain, sufficient impotence muscle contraction, the diseases such as cards such as hematuria blood drenches.
Ramulus cinnamomi：For the dry twig of lauraceae plant cortex cinnamomi (Cinnamomum cassia Presl).Acrid, sweet, warm, enter lung,
The heart, bladder meridian.Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi.Can cold-dispelling, cold, fever with chilliness etc. can be treated.
Herba Epimedii：Berberidaceae Epimedium herbaceos perennial, Herba Epimedii herb hyoscine.Cure mainly impotence and premature ejaculation, waist
Sour skelagia, numb limb, hemiplegia, neurasthenia, amnesia, tinnitus, dizzy equal diseases.
Monkshood：For the processed goods of the sub- root of the ranunculaceae plant rhizome of Chinese monkshood (Aconitum carmichaelii Debx).Acrid flavour,
It is sweet, extremely hot in nature.It belongs to the heart, kidney, spleen channel.Recuperating depleted yang, mends fire supporing yang, eliminating cold to stop pain.It collapses for yang depletion, cold weak pulse of limb, heart-yang
Deficiency, chest impediment and cardialgia, cold of insufficiency type vomiting and diarrhea, coldness and pain in the epigastrium, decline of kidney-YANG, impotence palace cold, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, numbness and ache of cold dampness.
Cortex cinnamomi：For the dry bark of lauraceae plant cortex cinnamomi (Cinnamomum cassia Presl).Extremely hot in nature, acrid flavour,
It is sweet.Return kidney channel, the spleen channel, the heart channel of Hang-Shaoyin, Liver Channel.Mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, warming meridian.Belong to drugs for dispelling internal cold.For sun
Impotence palace cold, waist and knee crymodynia, kidney deficiency characterized by dyspnea, deficient yang with upper manifestation, dizziness hot eyes, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold hernia stomachache, dysmenorrhea warp
It closes.
Scorpio：For the hirudo leech of Buthidae animal buthus martensii Karscs (Buthus martensii Karsch).Acrid flavour, it is mild-natured.
Return liver warp.Relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.For liver wind agitation, spasm is twitched, child convulsion, middle air port wai, and half
Body is unsuccessful, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.
Centipede：For Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH (Scolopendra subspinipes mutilansL.Koch)
Hirudo leech.Acrid flavour, it is warm-natured.Return liver warp.Relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.For liver wind agitation, spasm twitch, children
Infantile convulsion, middle air port wai, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula, snakebite and bugbite.
The larva of a silkworm with batrytis：Muscardine and the full worm of ossified drying are infected for the larva of Bombycidae insect silkworm.Acrid flavour is salty, mild-natured.
Tepor, it is slightly poisonous.Enter liver, lung, stomach meridian.It expels endogenous wind to relieve convulsion, reducing phlegm and resolving masses.Control apoplectic aphasia, frightened epilepsy, intermittent headache, sore-throat.Sore throat, scrofula
Scrofula tuberculosis.Wind sore urticaris, erysipelas, mazoitis.
The root of Dahurain angelica：For the dry root of the Umbelliferae herbaceos perennial root of Dahurain angelica or the anti-root of Dahurain angelica.It is acrid flavour, warm-natured.It attaches to the lung and stomach meridians.
Expelling cold and relieving exterior syndrome dispels pathogenic wind and remove dampness, detumescence and apocenosis, analgesic.For exterior syndrome due to wind-cold, have a headache, toothache, ulcerative carbuncle swelling and pain, morbid leucorrhoea duye.
Eupolyphoge sinensis：For Corydiidae eupolyphagasinensis walker (Eupolyph, aga sin, ensis Walker) or polyphagaplancyi
The female adult hirudo leech of (Steleophaga Plancyi (Boleny)).Taste is salty, cold in nature.Return liver warp.Dissipating blood stasis with potent drugs, reunion of fractured tendons and bones.
For traumatic injury, injury of tendon and muscle fracture, blood stasis, postpartum stasis abdominal pain, addiction lump in the abdomen lump in the abdomen.
Spina gleditsiae：For the drying quil of leguminous plant Chinese honey locust (Gleditsia sinensis Lam.).Acrid flavour, it is warm-natured.Return
Liver, stomach meridian.Detumescence and poison retention, apocenosis, desinsection.For ulcer from the beginning of or purulence at not bursting；Castor is controlled outside.
Lycopodium calvatum：For the drying herb of lycopsid lycopod (Lycopodium jaPonicum Thunb.).Bitter,
Micro-pungent, it is warm-natured.Liver,spleen,kidney is returned to pass through.There is the effect of dispelling wind and eliminating dampness, relaxing tendons and activating collaterals.For joint pain, joint stuffiness.
The rhizome of davallia：The dry rhizome of Plants of Polypodiaceae Mongolian oak fern (Drynaria fortunei (Kunze) J.Sm.).Property
Temperature, bitter.Return liver warp, kidney channel.Continues and hinders pain relieving, The strong bone of kidney tonifying.Belong to the blood-activating analgesic of drug for invigorating blood circulation and eliminating stasis subordinate classification.
The root of Chinese clematis：For the cohosh root of Chinese clematis (Clematis chinensis Osbeck), Clematis hexapetala
The dry root of (Clematis hexapetala Pall.) or northeast clematis (Clematis manshurica Rupr.) and
Rhizome.It is acrid flavour, salty, it is warm-natured.Return bladder meridian.There are wind-damp dispelling, the effect of degrading the channel.For rheumatic arthralgia, extremity numbness, tendon and vessel is arrested
Contraction, joint stuffiness.
Zaocys dhumnade：Zaocys dhumnade is commonly called as black snake, zaocys dhumnades, is the biggish snake of the Colubridae zaocys dhumnade category bodily form.Crow in Chinese medicine
Tip snake is this kind treated dry product.Sweet and neutral.Return liver warp.Wind-dispelling, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy
Facial paralysis, hemiplegia, spasm of twitching, tetanus, leprosy scabies, scrofula malignant sore.
Pangolin：Also known as armadillo scale, money carp first, pangolin are first-class, taste is salty；Cold nature.Return liver warp；Stomach meridian.Blood circulation promoting and dispersing pathogen accumulation；It is logical
Through lower cream；Anti-stain in solid.Cure mainly blood stasis；Disorder lump in the abdomen；Rheumatic arthralgia；Agalactia；Carbuncle swells；Scrofula.
Sesame oil：The fat oil squeezed for the seed of Pedaliaceae plant sesame.It is sweet in flavor, it is cool in nature.Major function is：It moisturizes logical
Just, detoxify, myogenic.Control dry constipation of intestines, roundworm, dyspeptic abdominalgia, sore swells, ulcer, scabies, chapped skin.
Yellow lead：Also known as red lead, it is acrid flavour, salty, it is cold in nature, it is toxic.Thoughts of returning home warp；The spleen channel；Liver Channel；Gallbladder channel；Kidney channel.Removing toxic substances is dispelled corruption；
Hygroscopic sore；Promoting expectoration to arrest convulsion.Ulcer sores；External piles；Eczema；Burn and scald；Ulcer；Metal-inflicted wound bleeding；Aphtha；Mesh screen；Frightened epilepsy is demented；
Malaria；Dysentery；Spit converse stomach.
Further, the ointment can also include following ingredients based on parts by weight：12-16 parts of camphor, preferably 13-15
Part.Camphor is a kind of terpene organic compound, is at room temperature white or transparent waxy solid.Sensible, desinsection, analgesic is warded off dirty.
Control trusted subordinate's distending pain, tinea pedis, sore scabies, toothache, traumatic injury.
Further, the ointment can also include following ingredients based on parts by weight：6-9 parts of borneol, preferably 7-8 parts.
Borneol also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing etc., are by composite family
Blumea balsamifera cauline leaf or lauraceae plant borneol camphor tree branches and leaves through steam distillation and are recrystallized and are obtained.It can be used for closing card coma, is used for
Red eye, swell pain, sore throat aphtha are used for sore swell and ache curative, do not hold back after bursting.
In addition above-mentioned external-applied ointment can add common pharmaceutic adjuvant in medicament preparation, in addition to figuration, serve as carrier, mention
Outside high stability, also there is solubilising, hydrotropy, delay the critical functions such as controlled release, including solvent, solubilizer, cosolvent, emulsifier,
Toner, disintegrating agent, filler, lubricant, wetting agent, osmotic pressure regulator, stabilizer, glidant, corrigent, is prevented binder
Rotten agent, suspending agent, coating material, aromatic, anti-binder, integrated agent, penetration enhancer, pH adjusting agent, buffer, plasticising
Agent, surfactant, foaming agent, defoaming agent, thickener, inclusion agents, moisturizer, absorbent, diluent, flocculant with it is deflocculated
Agent, filter aid, release retarding agent etc..
Under normal conditions, ointment is made according to existing common medicament preparation method in the mentioned component of the embodiment of the present invention
It uses, but other exterior-applied formulations can also be made, including external-use lotion, liniment, emplastrum, paste, patch etc., preferably ointment
Agent.
The embodiment of the invention also provides the external plasters of the treatment rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation
The preparation method of medicine, the method includes the following steps：
(1) take rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba, radix cyathulae,
Ramulus cinnamomi, Herba Epimedii, monkshood, cortex cinnamomi, the root of Dahurain angelica, spina gleditsiae, lycopodium calvatum, the rhizome of davallia and the root of Chinese clematis respectively with decocting system, filter out the dregs of a decoction and
Then impurity is condensed into lotion；Above-mentioned lotion is mixed, lotion mixture is obtained；
(2) pheretima, scorpio, centipede, the larva of a silkworm with batrytis, Eupolyphoge sinensis, zaocys dhumnade and pangolin are crushed, mixing, obtains powder mixing
Then powder mixture is added in above-mentioned lotion mixture, stirs while adding by object, obtain plaster precast body；
(3) above-mentioned plaster precast body is put into yellow lead, and gradually addition sesame oil is rubbed stirring, is uniformly mixed, and obtains institute
State externally applied ointment.
Further, the powder mixture in step (2) crosses 300 meshes by grinding.
It further, further include 12-16 parts of camphors of crushing after step (2), and smashed camphor addition lotion is pre-
The step of body processed.
It further, further include 6-9 parts of borneols of crushing after step (2), and smashed borneol addition lotion is prefabricated
The step of body.
In one embodiment, camphor and borneol cross 300 meshes by grinding.
Alternatively, the externally applied ointment of the embodiment of the present invention can also be made through the following steps：
1, spice extracts：Sesame oil is put in pot, the drug component other than borneol, camphor, myrrh, yellow lead is put into, text
Explosive wastewater, until fry to surface dark brown, it is internal sallow, 220 degree of temperature or so at this time；The dregs of a decoction are removed with sieve fishing after frying well, are
Medicine oil.
2, it refines oil：Above-mentioned medicine oil is taken to continue to temper：
(1) when refining oil, first is that seeing thermometer, 320 degree is raised to oil temperature, uses moderate heat instead；
(2) it sees oil smoke, starts as light cyan, be gradually black and dense, and then be white dense smoke；
(3) oil bloom are seen, are degree when oil bloom are assembled to pot center；
(4) it sees and drops into a bead, take during a little medicine oil drips, the beading that do not scatter is degree (has to refining to drop into a bead).
3, pilling and pasting：After medicine oil is smelt, from Huo Xiadan, yellow lead sieves with 100 mesh sieve before lower, and a small amount of lower pellet, side is stirred below,
Sticky lotion is stirred into, plaster is tack-free, and wire drawing is constantly preferably.
4, releasing fire-toxin：Plaster temperature drops to seventy or eighty when spending, and the myrrh side of thin medicine borneol, camphor, crushing is stirred below,
Then pour into releasing fire-toxin in water, it is secondary to change water daily, after seven days cream at.
5, plaster is melted with mild fire or water-bath；Be taped against on cloth.
The externally applied ointment of the embodiment of the present invention not only can treat rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation,
In addition there is good therapeutic effect for illnesss such as cervical spondylosis, scapulohumeral periarthritis, synovitis, strains.
The embodiment of the invention also provides the application method of the externally applied ointment, the method includes：Daily one to twice,
It is preferred that once in the morning and once at night, affected part is dried with warm water cleaning, the plaster is taken to be evenly coated in affected part.It is further preferred that will be described
After plaster is evenly coated in affected part, affected part is massaged.
Technical solution of the embodiment of the present invention has the following advantages that：
1, the externally applied ointment of the embodiment of the present invention passes through the rational allocation of mentioned component and dosage sum, can be to rheumatic waist
Have a pain in the leg, prolapse of lumbar intervertebral disc and osteoproliferation all generate it is preferable inhibit and therapeutic effect, it is easy to use；
2, this product with anti-inflammatory but also can not only relieve pain, significant in efficacy；And the effect for the treatment of both manifestation and root cause of disease can be played；
3, the antiphlogistic and analgesic ointment of the embodiment of the present invention is easily fabricated, and preparation method technology degree is high.
Specific embodiment
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
Embodiment 1
Externally applied ointment includes following ingredients based on parts by weight in the present embodiment：Rhizoma homalonemae, pawpaw, Chinese hydrangeavine root-bark, does not have Radix Angelicae Sinensis
Each 18 parts of medicine, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Each 22 parts of radix cyathulae, ramulus cinnamomi, Herba Epimedii；Monkshood, cortex cinnamomi are each
12 parts；Each 17 parts of scorpio, centipede；Each 30 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；15 parts of Eupolyphoge sinensis；20 parts of spina gleditsiae；28 parts of lycopodium calvatum；The rhizome of davallia 13
Part；10 parts of the root of Chinese clematis；20 parts of zaocys dhumnade；15 parts of pangolin；2500 parts of sesame oil；1200 parts of yellow lead.
Preparation method includes the following steps：
(1) take rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba, radix cyathulae,
Ramulus cinnamomi, Herba Epimedii, monkshood, cortex cinnamomi, the root of Dahurain angelica, spina gleditsiae, lycopodium calvatum, the rhizome of davallia and the root of Chinese clematis respectively with decocting system, filter out the dregs of a decoction and
Then impurity is condensed into lotion；Above-mentioned lotion is mixed, lotion mixture is obtained；
(2) pheretima, scorpio, centipede, the larva of a silkworm with batrytis, Eupolyphoge sinensis, zaocys dhumnade and pangolin are crushed, mixing, 300 mesh are crossed in grinding
Sieve obtains powder mixture, then powder mixture is added in above-mentioned lotion mixture, stirs while adding, and obtains plaster
Precast body；
(3) above-mentioned plaster precast body is put into yellow lead, and gradually addition sesame oil is rubbed stirring, is uniformly mixed, and obtains institute
State externally applied ointment.
Embodiment 2
Externally applied ointment includes following ingredients based on parts by weight in the present embodiment：Rhizoma homalonemae, pawpaw, Chinese hydrangeavine root-bark, does not have Radix Angelicae Sinensis
Each 16 parts of medicine, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Each 24 parts of radix cyathulae, ramulus cinnamomi, Herba Epimedii；Monkshood, cortex cinnamomi are each
14 parts；Each 16 parts of scorpio, centipede；Each 32 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；13 parts of Eupolyphoge sinensis；18 parts of spina gleditsiae；26 parts of lycopodium calvatum；The rhizome of davallia 14
Part；12 parts of the root of Chinese clematis；20 parts of zaocys dhumnade；16 parts of pangolin；2400 parts of sesame oil；1300 parts of yellow lead.
Preparation method is the same as embodiment 1.
Embodiment 3
Externally applied ointment includes following ingredients based on parts by weight in the present embodiment：Rhizoma homalonemae, pawpaw, Chinese hydrangeavine root-bark, does not have Radix Angelicae Sinensis
Each 17 parts of medicine, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Each 23 parts of radix cyathulae, ramulus cinnamomi, Herba Epimedii；Monkshood, cortex cinnamomi are each
13 parts；Each 17 parts of scorpio, centipede；Each 31 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；15 parts of Eupolyphoge sinensis；19 parts of spina gleditsiae；27 parts of lycopodium calvatum；The rhizome of davallia 13
Part；11 parts of the root of Chinese clematis；19 parts of zaocys dhumnade；15 parts of pangolin；2300 parts of sesame oil；1100 parts of yellow lead；15 parts of camphor；8 parts of borneol.
Preparation method on the basis of embodiment 1, increases after step (2) and crushes camphor and borneol, and will crush
The step of lotion precast body is added in rear camphor and borneol, wherein camphor and borneol are ground and cross 300 meshes.
Clinical trial example
Here is the clinical test of externally applied ointment treatment rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation of the invention
As a result.
1, clinical observation object
Rheumatic waist-leg aches patient 25, wherein male 13, female 12, the adult at 18 years old all age or more；
Lumbar disc herniation patient 35, wherein male 20, female 15, the adult at 18 years old all age or more；With
And
Osteoproliferation patient 25, wherein male 10, female 15, the adult at 18 years old all age or more.
2, treatment method
Patient, the ointment prepared in Application Example 3 are ached for rheumatic waist-leg；For lumbar disc herniation patient, answer
With the ointment prepared in embodiment 1；For osteoproliferation patient, the ointment that is prepared in Application Example 2.Daily morning and evening each one
Secondary, affected part warm water cleaning is simultaneously dried, and the plaster is taken to be evenly coated in affected part, and carries out massage 15 minutes.Two weeks is one
The course for the treatment of, 6 course of therapy.
Effect judgement：Clinical symptoms performance is all eliminated, and follow-up 3 months non-recidivists are recovery from illness；Eliminate 30% or more
Though symptom and do not fully recover repeatedly or within follow-up 3 months but alleviator is effective earlier above again；Other is invalid.
3, treatment results
Patient is ached for rheumatic waist-leg, is fully recovered 20, accounting 80%；Effective 5, accounting 20%；Invalid 0.
For lumbar disc herniation patient, fully recover 23, accounting about 65.7%；Effective 12, accounting about 34.3%；In vain
0.
For osteoproliferation patient, fully recover 18, accounting about 72.0%；Effective 7, accounting about 28.0%；Invalid 0.
Above-mentioned clinical test results show that externally applied ointment of the invention is to rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and sclerotin
Hyperplasia all generates preferable therapeutic effect, easy to use；It with anti-inflammatory but also can not only relieve pain, it is significant in efficacy；And it can rise
To the effect for the treatment of both manifestation and root cause of disease.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (10)
1. a kind of externally applied ointment for treating rheumatic waist-leg pain, prolapse of lumbar intervertebral disc and osteoproliferation, which is characterized in that the ointment
It based on parts by weight include following ingredients：Rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis,
Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba are 15-20 parts each；Radix cyathulae, ramulus cinnamomi, Herba Epimedii are 20-25 parts each；Monkshood, cortex cinnamomi are 10-15 parts each；Scorpio, centipede are each
15-20 parts；The larva of a silkworm with batrytis, the root of Dahurain angelica are 28-32 parts each；12-18 parts of Eupolyphoge sinensis；18-22 parts of spina gleditsiae；25-30 parts of lycopodium calvatum；Rhizome of davallia 10-
15 parts；8-13 parts of the root of Chinese clematis；18-23 parts of zaocys dhumnade；13-17 parts of pangolin；2200-2600 parts of sesame oil；Yellow lead 1000-1400
Part.
2. externally applied ointment according to claim 1, which is characterized in that the ointment include based on parts by weight it is following at
Point：Rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba are 16-18 parts each；River ox
Knee, ramulus cinnamomi, Herba Epimedii are 22-24 parts each；Monkshood, cortex cinnamomi are 12-14 parts each；Scorpio, centipede are 16-18 parts each；The larva of a silkworm with batrytis, the root of Dahurain angelica are each
30-32 parts；13-16 parts of Eupolyphoge sinensis；18-21 parts of spina gleditsiae；26-28 parts of lycopodium calvatum；12-14 parts of the rhizome of davallia；9-12 parts of the root of Chinese clematis；The black tip
18-21 parts of snake；14-16 parts of pangolin；2300-2500 parts of sesame oil；1100-1300 parts of yellow lead.
3. externally applied ointment according to claim 2, which is characterized in that the ointment include based on parts by weight it is following at
Point：Each 18 parts of rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Radix cyathulae,
Each 22 parts of ramulus cinnamomi, Herba Epimedii；Each 12 parts of monkshood, cortex cinnamomi；Each 17 parts of scorpio, centipede；Each 30 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；15 parts of Eupolyphoge sinensis；
20 parts of spina gleditsiae；28 parts of lycopodium calvatum；13 parts of the rhizome of davallia；10 parts of the root of Chinese clematis；20 parts of zaocys dhumnade；15 parts of pangolin；2500 parts of sesame oil；It is yellow
It is 1200 parts red.
4. externally applied ointment according to claim 2, which is characterized in that the ointment include based on parts by weight it is following at
Point：Each 16 parts of rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, pheretima, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba；Radix cyathulae,
Each 24 parts of ramulus cinnamomi, Herba Epimedii；Each 14 parts of monkshood, cortex cinnamomi；Each 16 parts of scorpio, centipede；Each 32 parts of the larva of a silkworm with batrytis, the root of Dahurain angelica；13 parts of Eupolyphoge sinensis；
18 parts of spina gleditsiae；26 parts of lycopodium calvatum；14 parts of the rhizome of davallia；12 parts of the root of Chinese clematis；20 parts of zaocys dhumnade；16 parts of pangolin；2400 parts of sesame oil；It is yellow
It is 1300 parts red.
5. externally applied ointment described in any one of -4 according to claim 1, which is characterized in that the ointment is gone back based on parts by weight
Including following ingredients：12-16 parts of camphor.
6. externally applied ointment described in any one of -4 according to claim 1, which is characterized in that the ointment is gone back based on parts by weight
Including following ingredients：6-9 parts of borneol.
7. the preparation method of externally applied ointment described in any one of -4 according to claim 1, which is characterized in that the method includes
The following steps：
(1) take rhizoma homalonemae, Radix Angelicae Sinensis, pawpaw, Chinese hydrangeavine root-bark, myrrh, Semen Cuscutae, Cortex Eucommiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Paeoniae Alba, radix cyathulae, ramulus cinnamomi,
Herba Epimedii, monkshood, cortex cinnamomi, the root of Dahurain angelica, spina gleditsiae, lycopodium calvatum, the rhizome of davallia and the root of Chinese clematis with decocting system, filter out the dregs of a decoction and impurity respectively,
Then it is condensed into lotion；Above-mentioned lotion is mixed, lotion mixture is obtained；
(2) pheretima, scorpio, centipede, the larva of a silkworm with batrytis, Eupolyphoge sinensis, zaocys dhumnade and pangolin are crushed, mixing, obtains powder mixture, so
Powder mixture is added in above-mentioned lotion mixture afterwards, is stirred while adding, plaster precast body is obtained；
(3) above-mentioned plaster precast body is put into yellow lead, and gradually addition sesame oil is rubbed stirring, is uniformly mixed, is obtained described outer
Use plaster.
8. preparation method according to claim 7, which is characterized in that the powder mixture in step (2) is by grinding, mistake
300 meshes.
9. preparation method according to claim 8, which is characterized in that further include crushing 12-16 parts of camphors after step (2)
With 6-9 parts of borneols, and the step of lotion precast body is added in smashed camphor and borneol.
10. preparation method according to claim 9, which is characterized in that camphor and borneol cross 300 meshes by grinding.
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