CN108813453A - A kind of edible composition for preventing and treating Parkinson's disease - Google Patents
A kind of edible composition for preventing and treating Parkinson's disease Download PDFInfo
- Publication number
- CN108813453A CN108813453A CN201810500741.4A CN201810500741A CN108813453A CN 108813453 A CN108813453 A CN 108813453A CN 201810500741 A CN201810500741 A CN 201810500741A CN 108813453 A CN108813453 A CN 108813453A
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- CN
- China
- Prior art keywords
- bluish dogbane
- vitamin
- dogbane seed
- composition
- seed
- Prior art date
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- Pending
Links
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Classifications
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The invention belongs to technical field of food preparation, are related to a kind of edible composition for preventing and treating Parkinson's disease；Its primary raw material includes：Product vitamin B1, vitamin B2, vitamin B6, vitamin B12, folic acid, biotin, niacin, pantothenic acid, laver powder, fructose, maltodextrin, lactalbumin, soybean protein, wheat-germ oil, choline, pectin, the sodium bicarbonate aqueous solution etc. that phytic acid, black shell bluish dogbane seed, dehydrated garlic and weight percent concentration are 0.3%；Preparation process includes the following steps：Vitamin combination is prepared, nutrient composition is prepared, prepares ripe bluish dogbane seed, preparation bluish dogbane seed garlic mixed serum and finished product preparation；Adjuvant treatment for parkinsonian, Abwehrkraft des Koepers can be improved and reduce complication, have the function of that anti-Parkinson and anti-aging, its composition use natural plant composition, Small side effects simultaneously, using safe, preparation process is simple, and principle is reliable, and preparation efficiency is high, good product quality, application environment are friendly.
Description
Technical field：
The invention belongs to technical field of food preparation, be related to a kind of food with prevention and anti-Parkinson's disease function and its
Preparation method, especially a kind of edible composition for preventing and treating Parkinson's disease, is added bluish dogbane seed garlic for powdered nutritional promotor composition
It is heated in mixed serum, obtains the functional food after cooling.
Background technique：
Parkinson's disease is a kind of common nervous system degeneration disease, is more common in the elderly, and average age of onset is 60 years old
The young Parkinson's disease of left and right, morbidity in 40 years old or less is more rare.The most important pathological change of Parkinson's disease is substantia nigra of midbrain DOPA
The denaturation of aminergic neuron is dead, and striatum DA level conspicuousness is caused to reduce and cause a disease therefrom.Lead to this pathological change
The definite cause of disease it is still unclear at present, inherent cause, environmental factor, age ageing and oxidative stress etc. may participate in PD DOPA
The denaturation death process of aminergic neuron.
The diagnosis of Parkinson's disease relies primarily on medical history, clinical symptoms and sign.General auxiliary examination change how without exception.
Drug therapy is the most important treatment means of Parkinson's disease, and Dopar is current most effective drug.Operative treatment is
One kind of drug therapy effectively supplement.Rehabilitation, psychotherapy and good nursing can also improve symptom to a certain extent.
Although the treatment means applied at present can only improve symptom, the progress of the state of an illness cannot be prevented, can not also cure disease, but effectively
Treatment can significantly improve the quality of life of patient.
Currently, extremely being paid close attention to for treating and preventing the research and development of anti-parkinson drug both at home and abroad, few concern preventions
With the functional food of anti-Parkinson's disease.Chinese Patent Application No. is that the patent of invention of CN201210402024.0 discloses one kind
" application of arctiin and aglycon in anti-Parkinson's disease ", which shows arctiin by internal and external test result
And its aglycon has stronger anti-Parkinson's disease effect.Treatment due to the particularity of Parkinson's disease, with Parkinson disease
It compares, seems even more important for the prevention of the disease.Life is rough by Parkinsonian to take care of oneself, and is easy nutritional deficiency, the present invention
It seeks to design a kind of specific functional food, phytic acid etc. is added while improving the nutrition and immunity of patient has pole
High anti-oxidation, anti-inflammatory and multiple target point anti-Parkinson function raw material, make it have protection dopaminergic neuron function with
And prevent and assist in the treatment of Parkinson's disease function.The functional food is also suitble to the above the elderly of threescore as prevention pa simultaneously
Golden Sen Shi disease functional food, and there is auxiliary therapeutic action to parkinsonian, to improve Abwehrkraft des Koepers and subtract
Few complication.In raw material in the functional food, starch and dextrin can provide energy, and lactalbumin and soybean protein are as high-quality
Albumen improves immunity of organisms, and B family vitamin can provide various coenzyme needed for nutrient metabolism, and choline can maintain brain
Basic transmitter acetylcholine needed for memory, alleviates the symptom of hypomnesia in parkinsonian's complication, pectin conduct
Dietary fiber can promote the breeding of beneficial bacteria of intestinal tract, while promote gastrointestinal peristalsis, and phytic acid has the function of chelating divalent metal ions,
As extremely strong antioxidant, blood-brain barrier may pass through, there is protective effect to dopaminergic neuron in Parkinson's disease.Institute
To invent a kind of functional food that suitable Parkinsonian is made using natural component, make it have enhancing Parkinson's sufferer
The function of person's immunity, anti-Parkinson and anti-aging has adjuvant treatment and early prevention function to parkinsonian, has
Good application value.
Summary of the invention：
It is an object of the invention to overcome disadvantage of the existing technology, seek to design a kind of with prevention and treatment Parkinson's disease function
The edible composition of energy, product can play the functional effect of prevention and treatment Parkinson's disease by chronic dietary.
To achieve the goals above, each raw material of edible composition component by weight of prevention and treatment Parkinson's disease of the present invention
For：Product vitamin B1 1.4mg, vitamin B2 1.2mg, vitamin B6 1.5mg, vitamin B12 2.4 μ g, folic acid 1mg,
Biotin 30 μ g, niacin 14mg/d, pantothenic acid 5.0mg, laver powder 10g, fructose 10g, maltodextrin 10g, lactalbumin 30g, greatly
35 grams of legumin, 2 grams of wheat-germ oil, choline 500mg, pectin 2g, phytic acid 2g, black shell bluish dogbane seed 200g, dehydrated garlic 1000~
1200g, sodium bicarbonate aqueous solution 3000g~4000g that weight percent concentration is 0.3%.
The edible composition preparation process of prevention and treatment Parkinson's disease of the present invention includes step in detail below：
(1) vitamin combination is prepared：Take product vitamin B1 1.4mg, vitamin B2 1.2mg, vitamin B6
1.5mg, vitamin B12 2.4 μ g, folic acid 1mg, biotin 30 μ g, niacin 14mg/d, pantothenic acid 5.0mg tie up above-mentioned various B races
The powdery B family vitamin composition that raw element mixture is ground into 200 mesh with glass mortar is spare；
(2) nutrient composition is prepared：The nutrient composition of the powdery is in terms of weight 100g, including following components：It is purple
Vegetable powder 10g, fructose 10g, maltodextrin 10g, lactalbumin 30g, 35 grams of soybean protein, 2 grams of wheat-germ oil, choline 500mg, pectin
2g, phytic acid 2g, the above various nutrients are ground into 200 mesh mixing powderies with glass mortar, then with powdery obtained in step (1)
The nutrient composition that powdery is obtained after the mixing of B family vitamin composition is spare；Wherein, seaweed used selects commercially available dry product seaweeds purple
Dish product；
(3) ripe bluish dogbane seed is prepared：The black shell bluish dogbane seed 200g for choosing fresh mature, adds water to just and did not had bluish dogbane seed,
Bluish dogbane seed is taken out after impregnating 10~20 minutes progress broken skins under room temperature, bluish dogbane seed surface moisture is blotted with blotting paper, will be drained
The bluish dogbane seed of moisture, which is put into be gradually heated up in nonmetal pot, to stir-fry, and is gradually heated to 150~180 DEG C of stirring stir-fryings 10~15
Minute, fire is closed after savory and takes out ripe bluish dogbane seed, ripe bluish dogbane seed is put into bamboo weaving container spare after cooling；
(4) bluish dogbane seed garlic mixed serum is prepared：Commercially available 1000~1200g of dehydrated garlic is chosen, it is obtained with step (3)
To the mixing of ripe bluish dogbane seed after be put into stone mill and carry out barreling, as stone mill is rotated, that weight percent is uniformly added into wear eye is dense
Degree makes sodium bicarbonate aqueous solution and bluish dogbane seed garlic under the action of grinding for 0.3% sodium bicarbonate aqueous solution 3000g~4000g
Uniform slurries are mixed into, slurries are taken out, with obtaining bluish dogbane seed garlic mixed serum after the non-full missing yarn net filtration of 200 mesh；
(5) prepared by finished product：The bluish dogbane seed garlic mixed serum that step (4) obtains is put into ceramic vessel, is heated to 50
Fire is closed after~60 DEG C, it is mixed that 1500~2000 grams of bluish dogbane seed garlics are added in the powdered nutritional promotor composition 100g for taking step (3) to obtain
It closes and is stirred evenly in slurries, edible composition drink is obtained when being cooled to room temperature, for oral prevention and treatment Parkinson's disease, experiment knot
Fruit explanation, control efficiency effective percentage is up to 83% or more.
Compared with prior art, the present invention it is intended to prepare specific functional food, the auxiliary for parkinsonian
Treatment, while can be improved Abwehrkraft des Koepers by various nutrients and reducing complication, while have anti-Parkinson and anti-ageing
Old function has adjuvant treatment and early prevention function to parkinsonian；Its composition uses natural plant composition, secondary
Act on small, use is safe, and preparation process is simple, and principle is reliable, and preparation efficiency is high, good product quality, and application environment is friendly.
Specific embodiment：
The present invention is described further below by specific embodiment.
Embodiment 1：
The specific preparation process of the edible composition for the prevention and treatment Parkinson's disease that the present embodiment is related to includes the following steps：
(1) vitamin combination is prepared：Take product vitamin B1 1.4mg, vitamin B2 1.2mg, vitamin B6
1.5mg, vitamin B12 2.4 μ g, folic acid 1mg, biotin 30 μ g, niacin 14mg/d, pantothenic acid 5.0mg tie up above-mentioned various B races
The powdery B family vitamin composition that raw element mixture is ground into 200 mesh with glass mortar is spare；
(2) nutrient composition is prepared：The nutrient composition of the powdery is in terms of weight 100g, including following components：It is purple
Vegetable powder 10g, fructose 10g, maltodextrin 10g, lactalbumin 30g, 35 grams of soybean protein, 2 grams of wheat-germ oil, choline 500mg, pectin
2g, phytic acid 2g, the above various nutrients are ground into 200 mesh mixing powderies with glass mortar, then with powdery obtained in step (1)
The nutrient composition that powdery is obtained after the mixing of B family vitamin composition is spare；Wherein, seaweed used selects commercially available dry product seaweeds purple
Dish product；
(3) ripe bluish dogbane seed is prepared：The black shell bluish dogbane seed 200g for choosing fresh mature, adds water to just and did not had bluish dogbane seed,
Bluish dogbane seed is taken out after impregnating 10~20 minutes progress broken skins under room temperature, bluish dogbane seed surface moisture is blotted with blotting paper, will be drained
The bluish dogbane seed of moisture, which is put into be gradually heated up in nonmetal pot, to stir-fry, and is gradually heated to 150~180 DEG C of stirring stir-fryings 10~15
Minute, fire is closed after savory and takes out ripe bluish dogbane seed, ripe bluish dogbane seed is put into bamboo weaving container spare after cooling；
(4) bluish dogbane seed garlic mixed serum is prepared：Commercially available 1000~1200g of dehydrated garlic is chosen, it is obtained with step (3)
To the mixing of ripe bluish dogbane seed after be put into stone mill and carry out barreling, as stone mill is rotated, that weight percent is uniformly added into wear eye is dense
Degree makes sodium bicarbonate aqueous solution and bluish dogbane seed garlic under the action of grinding for 0.3% sodium bicarbonate aqueous solution 3000g~4000g
Uniform slurries are mixed into, slurries are taken out, with obtaining bluish dogbane seed garlic mixed serum after the non-full missing yarn net filtration of 200 mesh；
(5) prepared by finished product：The bluish dogbane seed garlic mixed serum that step (4) obtains is put into ceramic vessel, is heated to 50
Fire is closed after~60 DEG C, it is mixed that 1500~2000 grams of bluish dogbane seed garlics are added in the powdered nutritional promotor composition 100g for taking step (3) to obtain
It closes and is stirred evenly in slurries, edible composition drink is obtained when being cooled to room temperature, for oral prevention and treatment Parkinson's disease, experiment knot
Fruit explanation, control efficiency effective percentage is up to 83% or more.
Embodiment 2：
The specific preparation process of the present embodiment is same as Example 1, and difference is in step (4) that preparation bluish dogbane seed is big
Garlic mixed serum is handled using wall-breaking machine, is ground in step (1) using low speed, and nutritional ingredient is not compromised, stone mill and big
Garlic, bluish dogbane seed rub naturally, and the minerals that stone mill contains naturally are mixed with garlic, bluish dogbane seed nutrient, combine together, nutrition
Health, but stone mill working efficiency is low, and cost of labor is big, it is contemplated that industrialized input and output, selection are produced using wall-breaking machine
Bluish dogbane seed garlic mixed serum can break up food cells wall, release plant biochemistry element, by the vitamin in cell, mine with moment
Substance, plant element, protein and moisture etc. sufficiently release；It is operated using wall-breaking machine, working efficiency can also be improved, favorably
In industrialized production, while being also beneficial to sufficiently discharge the effective component of bluish dogbane seed and garlic；
The specific preparation process of the edible composition for the prevention and treatment Parkinson's disease that the present embodiment is related to includes the following steps：
(1) B family vitamin composition is prepared：Take vitamin B1 1.4mg, vitamin B2 1.2mg, vitamin B6
1.5mg, vitamin B12 2.4 μ g, folic acid 1mg, biotin 30 μ g, niacin 14mg/d, pantothenic acid 5.0mg, by above-mentioned B family vitamin
It is spare that composition with glass mortar is ground into 200 mesh powderies；
(2) powdered nutritional promotor composition is prepared：The powdered nutritional promotor composition is in terms of weight 100g, including following components：
Dried seaweed finished powder 10g, rock sugar 10g, maltodextrin 10g, lactalbumin 30g, soybean protein 35, wheat-germ oil (2ml), choline
500mg, pectin 2g, phytic acid 2g, the above various nutrients are ground into 200 mesh powderies with glass mortar, and with obtained in step (1)
Powdery B family vitamin composition mixing after powdered nutritional promotor composition it is spare；
(3) ripe bluish dogbane seed is prepared：The black shell bluish dogbane seed 200g for choosing fresh mature, adds water to just and did not had bluish dogbane seed,
Immersion 10~take out bluish dogbane seed after twenty minutes, bluish dogbane seed surface moisture is blotted, the bluish dogbane seed to drain away the water is put with blotting paper
Enter to be gradually heated up in nonmetal pot and stir-fry, so that pot is gradually heated to 150~180 DEG C and stir-fry 10~15 minutes, to savory
It closes fire and takes out ripe bluish dogbane seed, ripe bluish dogbane seed is put into bamboo weaving container cooling；
(4) bluish dogbane seed garlic mixed serum is prepared：Commercially available 1000~1200g of dehydrated garlic is chosen, it is obtained with step (3)
To ripe bluish dogbane seed mixing after be put into wall-breaking machine, then be added weight percent concentration be 0.3% sodium bicarbonate aqueous solution
3000g~4000g broken wall treatment 1~2 minute, takes out bluish dogbane seed garlic mixed solution, will obtain by broken wall treatment
The mixed solution that arrives takes out, with obtaining bluish dogbane seed garlic mixed serum after 200 mesh filtered through gauze；
(5) prepared by finished product：Bluish dogbane seed garlic mixed serum obtained in step (4) is put into earthen container, is heated to
Fire is closed after 50~60 DEG C, the powdered nutritional promotor composition 100g for taking step (2) to obtain is added to 1500~1600g bluish dogbane seed garlic
It is stirred evenly in mixed serum, obtains edible composition drink when bluish dogbane seed garlic mixed serum is cooled to room temperature, take orally 3~6
It can take effect within a month；Parkinson's disease is prevented and treated, testing result effective percentage reaches 80% or more.
Embodiment 3：
The present embodiment is related to a kind of application method of edible composition for preventing and treating Parkinson's disease, function edible composition tool
Have enhancing Parkinsonian's immunity, the function of anti-Parkinson and anti-aging, to parkinsonian have adjuvant treatment and
Early prevention function, which is put into earthen container, and Radix Codonopsis and fructus lycii can be aided with etc., it is to be mixed
80~85 DEG C are heated in earthen container afterwards to there is hot gas to wait for when emerging 1~2 minute, then flame-out is naturally cooling to 30~40 DEG C
Shi Yinyong, the elderly and disturbances in patients with Parkinson disease can be drunk sooner or later, every time 20~50g, and there is enhancing nutrition to improve immunity of organisms, mention
Refreshing restoring consciouness effect is the functional food of suitable parkinsonian a kind of, has enhancing parkinsonian's immunity, resists
The function of Parkinson and anti-aging has adjuvant treatment and early prevention function to parkinsonian, prevents and treats efficient high
In 80%.
Claims (2)
1. a kind of edible composition for preventing and treating Parkinson's disease, it is characterised in that each raw material component by weight is：Product vitamin B1
1.4mg, vitamin B2 1.2mg, vitamin B6 1.5mg, vitamin B12 2.4 μ g, folic acid 1mg, 30 μ g of biotin, niacin
14mg/d, pantothenic acid 5.0mg, laver powder 10g, fructose 10g, maltodextrin 10g, lactalbumin 30g, 35 grams of soybean protein, wheat germ
2 grams, choline 500mg, pectin 2g, phytic acid 2g, black shell bluish dogbane seed 200g, 1000~1200g of dehydrated garlic of oil, weight percent
Sodium bicarbonate aqueous solution 3000g~4000g that concentration is 0.3%.
2. a kind of edible composition for preventing and treating Parkinson's disease according to claim 1, it is characterised in that preparation process includes
Step in detail below：
(1) vitamin combination is prepared：Product vitamin B1 1.4mg, vitamin B2 1.2mg, vitamin B6 1.5mg are taken, is tieed up
Raw 2.4 μ g of element B12, folic acid 1mg, biotin 30 μ g, niacin 14mg/d, pantothenic acid 5.0mg mix above-mentioned various B family vitamins
The powdery B family vitamin composition that object is ground into 200 mesh with glass mortar is spare；
(2) nutrient composition is prepared：The nutrient composition of the powdery is in terms of weight 100g, including following components：Laver powder
10g, fructose 10g, maltodextrin 10g, lactalbumin 30g, 35 grams of soybean protein, 2 grams of wheat-germ oil, choline 500mg, pectin 2g,
Phytic acid 2g, the above various nutrients are ground into 200 mesh mixing powderies with glass mortar, then with powdery B race obtained in step (1)
The nutrient composition that powdery is obtained after vitamin combination mixing is spare；Wherein, seaweed used selects commercially available dry product seaweeds seaweed
Product；
(3) ripe bluish dogbane seed is prepared：The black shell bluish dogbane seed 200g for choosing fresh mature, adds water to just and did not had bluish dogbane seed, room temperature
Bluish dogbane seed is taken out after 10~20 minutes progress broken skins of lower immersion, and bluish dogbane seed surface moisture is blotted with blotting paper, will be drained away the water
Bluish dogbane seed be put into be gradually heated up in nonmetal pot and stir-fry, be gradually heated to 150~180 DEG C of stirrings and stir-fry 10~15 points
Clock closes fire after savory and takes out ripe bluish dogbane seed, ripe bluish dogbane seed is put into bamboo weaving container spare after cooling；
(4) bluish dogbane seed garlic mixed serum is prepared：Commercially available 1000~1200g of dehydrated garlic is chosen, it is obtained with step (3)
It is put into stone mill after the mixing of ripe bluish dogbane seed and carries out barreling, be uniformly added into weight percent concentration into wear eye as stone mill is rotated and be
0.3% sodium bicarbonate aqueous solution 3000g~4000g mixes sodium bicarbonate aqueous solution and bluish dogbane seed garlic under the action of grinding
At uniform slurries, slurries are taken out, with obtaining bluish dogbane seed garlic mixed serum after the non-full missing yarn net filtration of 200 mesh；
(5) prepared by finished product：The bluish dogbane seed garlic mixed serum that step (4) obtains is put into ceramic vessel, is heated to 50~60
Fire is closed after DEG C, 1500~2000 grams of bluish dogbane seed garlic mixing slurries are added in the powdered nutritional promotor composition 100g for taking step (3) to obtain
It is stirred evenly in liquid, edible composition drink is obtained when being cooled to room temperature, for oral prevention and treatment Parkinson's disease, experimental result is said
Bright, control efficiency effective percentage is up to 83% or more.
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| CN111374986A (en) * | 2018-12-28 | 2020-07-07 | 天津科技大学 | Application of vitamin B12 as α -synuclein aggregation inhibitor in preparation of medicines, health-care products or foods |
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Application publication date: 20181116 |