CN108785577A - Radix Angelicae Sinensis Radix Glycyrrhizae decoction - Google Patents

Radix Angelicae Sinensis Radix Glycyrrhizae decoction Download PDF

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CN108785577A
CN108785577A CN201710293953.5A CN201710293953A CN108785577A CN 108785577 A CN108785577 A CN 108785577A CN 201710293953 A CN201710293953 A CN 201710293953A CN 108785577 A CN108785577 A CN 108785577A
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angelicae sinensis
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燕巧红
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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Abstract

It is swollen Radix Angelicae Sinensis glycyrrhiza decoction agent formulation for oral administration the invention discloses a kind of for treating stock, which is characterized in that the Chinese medicine material and parts by weight of selection be respectively:20 grams of Radix Angelicae Sinensis, 60 grams of radix paeoniae rubra, 30 grams of dried orange peel, 30 grams of coix seed, 20 grams of Radix Glycyrrhizae, 30 grams of smilax, 30 grams of the root of fangji, 30 grams of honeysuckle, 20 grams of radix scrophulariae, 30 grams of peach kernel, 18 grams of safflower, 21 grams of madder, 21 grams of Herba Lycopi.Raw medicinal material pharmacological property effect selected by the present invention is complementary, evaded the mutual inhibition of compatibility between drug, mutual restraint between two drugs, the mutual-detoxication choosing, make drug mutual reinforcement between, mutually make effect notable, there is clearing heat and expelling damp, regulating qi-flowing for eliminating phlegm, effect promoting blood circulation and removing blood stasis.Orally taken for curing stock is swollen, has definite curative effect.

Description

Radix Angelicae Sinensis Radix Glycyrrhizae decoction
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Radix Angelicae Sinensis Radix Glycyrrhizae decoction, for treating the swollen innerwear Chinese medicine preparation of stock, With clearing heat and expelling damp, regulating qi-flowing for eliminating phlegm, effect promoting blood circulation and removing blood stasis.
Background technology
Swollen stock is that deep vein thrombosis is formed and a kind of disease caused by inflammatory lesion.Its main feature is that having long-term sleeping more Bed, childbirth or history of operation, suffering limb swelling pain, Pi Wen are increased, and Superficial veins appear.It is equivalent to the thrombotic Deep venou of doctor trained in Western medicine It is scorching.If this disease early diagnoses, treat in time, general prognosis bona.But phlebothrombosis easily causes lung infraction or pulmonary embolism after falling off. This disease cause of disease mainly has two aspects:One is damp and hot for blood stasis, and two be the blood stasis deficiency of vital energy.If the sleeping braking of sitting, or operation, trauma, Stagnation of QI-blood, damp and hot take advantage of a weak point in opponent's defence are invaded, then limb swelling pain;If the course of disease is with the passing of time, wasting QI-blood, stagnation of QI-blood, then suffering limb swelling With the passing of time do not disappear, blue veins appears.Mostly by crouching long, sitting, in postpartum, abdomen or operation on pelvis, the rear braking such as wound, QI-blood circulation are stagnant Slow or trauma surgery damages tendon and vessel, and QI-blood circulation is unsmooth, so that the roads hemostasis Zu Yuluo, train of thought blocks obstructed, ying blood backflow obstruction It overflows in outside arteries and veins, streamer lower limb form.
Invention content
The present invention relates to the field of Chinese medicines, and in particular to one kind for treat stock swell innerwear Chinese medicine preparation, have clearing heat and expelling damp, Regulating qi-flowing for eliminating phlegm, effect promoting blood circulation and removing blood stasis.It is for oral administration, it can be used for the swollen treatment of stock, there is definite curative effect.
Present invention employs the following technical solutions to achieve the above object:The medicinal material of Chinese medicine preparation selection of the present invention And parts by weight are respectively:20 grams of Radix Angelicae Sinensis, 60 grams of radix paeoniae rubra, 30 grams of dried orange peel, 30 grams of coix seed, 20 grams of Radix Glycyrrhizae, 30 grams of smilax, the root of fangji 30 grams, 30 grams of honeysuckle, 20 grams of radix scrophulariae, 30 grams of peach kernel, 18 grams of safflower, 21 grams of madder, 21 grams of Herba Lycopi.
In the Chinese medicine material that the present invention selects:Radix Angelicae Sinensis:【Chemical composition】Containing basic lactone, n-butene acyl lactone, ferulic acid, Niacin, sucrose and a variety of amino acid and sesquiterpenoids etc..【Meridian distribution of property and flavor】It is warm-natured, it hides sweet, pungent.Return liver, the heart, spleen Through.【Major function】Replenishing and activating blood, menstruction regulating and pain relieving relax bowel.For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, Amenorrhea pain Through, asthenia cold abdominalgia, dry constipation of intestines, arthralgia pain due to rheumatism, injury from falling down, ulcer sores.
Radix paeoniae rubra:Function, the row stasis of blood, analgesic, cool blood, detumescence.It cures mainly:Control the stagnant Amenorrhea of the stasis of blood, the accumulation of hernia lump in the abdomen, abdominal pain, hypochondriac pain, nosebleed Blood, bloody flux, discharging fresh blood stool, hot eyes, carbuncle swells, injury from falling down.
Dried orange peel:Dried orange peel contains hesperidine about 8.4%, Nobiletin(nobiletin)About 0.15%. separately contain synephrine(To hydroxyl good fortune Woods)0.28%-2.54%.【Nature and flavor】It is bitter, acrid in flavour and warm in nature.【Channel tropism】Return lung, the spleen channel.【Attending effectiveness】:Regulating qi-flowing for strengthening spleen, it is dry in tune It is wet, resolving sputum.Cure mainly the abdominal fullness and distention or pain, indigestion of the taste stagnation of the circulation of vital energy.Abdominal distension uncomfortable in chest, indigestion and loss of appetite loose stool in wet turbid resistance.Phlegm The wet cough and asthma for stopping up lung.For chest gastral cavity turgor, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Coix seed,:Channel tropism:Enter spleen, lung, kidney channel.Effect:Invigorating the spleen, tonifying lung, heat-clearing, dampness removing.Diarrhea, arthritis with fixed pain caused by dampness are controlled, tendon and vessel is arrested Contraction, joint stuffiness, oedema, tinea pedis, consumptive lung disease, lung carbuncle, acute appendicitis, stranguria with turbid discharge, leukorrhea.
Radix Glycyrrhizae:It is mild-natured, it is sweet in flavor.Major function:It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription. For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation drug poison Property, it is strong, in Chinese medicine, Radix Glycyrrhizae is invigorated the spleen and benefited qi, relieving cough and moistening lung, emergency removing toxic substances, reconcile hundred medicines.
Smilax:【Function】Removing toxic substances, dehumidifying, sharp joint.It cures mainly:Control syphilis, stranguria with turbid discharge, muscles and bones contraction pain, tinea pedis treats furunculosis, Limbs contraction caused by carbuncle swells, scrofula, syphilis and mercury poisoning, arthralgia and myalgia.
The root of fangji:Effect:Inducing diuresis for removing edema, wind-expelling pain-stopping.It cures mainly:Oedema tinea pedis, difficult urination, eczema sore, arthralgia pain due to rheumatism, Vascular hypertension.It is generally believed that the effect of Stephania tetrandra inducing diuresis for removing edema is stronger, the effect of Cocculus trilobus wind-expelling pain-stopping is preferable.
Honeysuckle:【Meridian distribution of property and flavor】It is sweet in flavor;It is cold.Return lung;Stomach.【Effect】It is clearing heat and detoxicating.Warm disease heating;Heat toxin blood Dysentery;Carbuncle swells furunculosis;Larynx numbness and multi-infection disease.
Radix scrophulariae:【Meridian distribution of property and flavor】:It is sweet in flavor, bitter, salty;Cold nature.Return lung, stomach, kidney channel.【Effect】:Clearing heat and cooling blood, purging intense heat Removing toxic substances, enriching yin.It cures mainly:Warm heat disease and ying blood, body heat, polydipsia, tongue be deep red, macular eruption, hectic fever due to yin labor is coughed, dysphoria not awake, Tianjin hinder constipation, mesh Puckery dim-sighted, throat larynx swelling and pain, scrofula subcutaneous nodule, skin sore.
Peach kernel:【Meridian distribution of property and flavor】Bitter, sweet, flat.The thoughts of returning home, liver, large intestine channel.【Major function】Promoting blood circulation relaxes bowel, only Cloperastine is breathed heavily.For Amenorrhea, dysmenorrhoea , wei lump in the abdomen lump in the abdomens, injury from falling down, dry constipation of intestines.
Safflower:【Chemical composition】Containing carthamin, neocarthamin, safflower quinone glucoside, safflower polysaccharide, palmitic acid, cinnamic acid, bay Acid.【Nature and flavor】It is warm-natured, acrid flavour.【Major function】Invigorate blood circulation, scattered silt analgesic, is used for amenorrhoea, dysmenorrhoea, lochia, abdominal mass Lump in the abdomen, injury from falling down, sore swell and ache curative.
Madder:【Major function】Cool blood, hemostasis, dissolving stasis, promoting menstruation, antibechic, eliminating the phlegm.For spitting blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, wound Bleeding, Amenorrhea stasis blocking, joint pain, tumbling and swelling.Modern medicine clinical research:Hemorrhagic illness, Chronic Airway can be treated Inflammation, chronic diarrhea, rheumatic arthritis treat soft tissue injury, treat leukopenia.
Herba Lycopi:【Ingredient】Containing volatile oil, glycoside, tannin and resin;Also contain flavonoids, phenols amino acid is organic Acid, saponin, various saccharides.【Nature and flavor, channel tropism】Pungent, tepor enters liver, bladder warp.【Function】Promoting blood circulation, diuresis detumescence.【It is main It controls】For amenorrhea due to stagnation of blood, disease purplish or white patches on the skin, postpartum stasis caused pain, oedema, traumatic injury.
Raw medicinal material pharmacological property effect selected by the present invention is complementary, evaded the mutual inhibition of compatibility between drug, mutual restraint between two drugs, the mutual-detoxication it Choosing, makes drug mutual reinforcement between, mutually makes effect notable, has and improves immunity, clearing heat and expelling damp, regulating qi-flowing for eliminating phlegm, effect promoting blood circulation and removing blood stasis.It is interior Clothes treatment stock is swollen, has definite curative effect.
It is achieved unexpected by clinical application using of the present invention for treating the swollen innerwear Chinese medicine preparation of stock Promising result;
Drug therapy stock of the present invention swells clinical observation:
1. general information
Accept out-patient totally 23 for medical treatment, age 20-30 Sui 3,31-40 Sui 6,41-50 Sui 6,50 years old or more 8.
2. it is as follows that case is embodied:Sun, man, 71 years old, in first visit on the 4th in 2 months in 2009.With right leg swelling more than 40 It is chief complaint to examine.Patient in mid-December, 2008, Zeng Yin " hypertrophy of the prostate " in local hospital row operative treatment, it is postoperative go out Existing right leg swelling, pain are prompted in local row contrast examination:Left lower extremity venous thronbosis.After treatment, pain is mitigated. Indagation is shown in:Right lower extremity shin bone epimere falls into property to the swelling at ankle, in non-refer to.Dry and hard excrement, red tongue body, thick,yellow and greasy fur, arteries and veins Sliding number.Come with the prompt of veins of lower extremity direct motion radiography:The outer vein of right lower extremity bone and common iliac vein thrombosis.It examines and swells for stock(It is right Lower limb deep venous thrombosis), card category damp-heat type, thermogravimetric is in wet.It controls with clearing heat and expelling damp, regulating qi-flowing for eliminating phlegm, promoting blood circulation and removing blood stasis.With throwing 21 doses of prescription of the present invention, takes daily 1 dose, divides 2 times sooner or later and warmly takes, empty stomach boiling water is taken after mixing it with water.With examining later.Patient's limb swelling is apparent Mitigate, tongue nature is light, and tongue is thin white, deep-slow pulse.10 courses for the treatment of of following the service, all diseases are all removed.It is enjoined, one course for the treatment of of continual cure, which is consolidated, to be treated Effect.Take several doses i.e. more.
Specific implementation mode
It is described to swell innerwear Chinese medicine preparation for treating stock, which is characterized in that the Chinese medicine material and parts by weight of selection be respectively: 20 grams of Radix Angelicae Sinensis, 60 grams of radix paeoniae rubra, 30 grams of dried orange peel, 30 grams of coix seed, 20 grams of Radix Glycyrrhizae, 30 grams of smilax, 30 grams of the root of fangji, honeysuckle 30 Gram, 20 grams of radix scrophulariae, 30 grams of peach kernel, 18 grams of safflower, 21 grams of madder, 21 grams of Herba Lycopi;
Preparation method:20 grams of Radix Angelicae Sinensis, 60 grams of radix paeoniae rubra, 30 grams of dried orange peel, 30 grams of coix seed, 20 grams of Radix Glycyrrhizae, 30 grams of smilax, the root of fangji 30 Gram, 30 grams of honeysuckle, 20 grams of radix scrophulariae, 30 grams of peach kernel, 18 grams of safflower, 21 grams of madder, 21 grams of Herba Lycopi;Medicine materical crude slice is respectively prepared, passes through Pressure cooker cooking disinfection 40-70 minutes, dries, and obtains aseptic raw material, is sealed packaging, obtains commodity Chinese medicine preparation drink Product.

Claims (2)

1. for treating the swollen Radix Angelicae Sinensis glycyrrhiza decoction agent formulation for oral administration of stock, which is characterized in that the Chinese medicine material and parts by weight of selection point It is not:20 grams of Radix Angelicae Sinensis, 60 grams of radix paeoniae rubra, 30 grams of dried orange peel, 30 grams of coix seed, 20 grams of Radix Glycyrrhizae, 30 grams of smilax, 30 grams of the root of fangji, gold and silver Spend 30 grams, 20 grams of radix scrophulariae, 30 grams of peach kernel, 18 grams of safflower, 21 grams of madder, 21 grams of Herba Lycopi.
The innerwear Chinese medicine preparation 2. treatment stock according to claim 1 swells, it is characterised in that:Preparation method is following step Suddenly:Step 1)Weigh raw medicinal material:20 grams of Radix Angelicae Sinensis, 60 grams of radix paeoniae rubra, 30 grams of dried orange peel, 30 grams of coix seed, 20 grams of Radix Glycyrrhizae, smilax 30 grams, 30 grams of the root of fangji, 30 grams of honeysuckle, 20 grams of radix scrophulariae, 30 grams of peach kernel, 18 grams of safflower, 21 grams of madder, 21 grams of Herba Lycopi;
Step 2:The medicine materical crude slice that will be obtained was dried by pressure cooker cooking disinfection 40-70 minutes, obtained aseptic raw material;
Step 3:The aseptic raw material that will be obtained is sealed packaging, obtains commodity Chinese medicine preparation drink.
CN201710293953.5A 2017-04-28 2017-04-28 Radix Angelicae Sinensis Radix Glycyrrhizae decoction Pending CN108785577A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031020A (en) * 2015-06-28 2015-11-11 成都市飞龙水处理技术研究所 Decoction medicine for treating thrombophlebitis and preparation method for decoction medicine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031020A (en) * 2015-06-28 2015-11-11 成都市飞龙水处理技术研究所 Decoction medicine for treating thrombophlebitis and preparation method for decoction medicine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
南喜连: "通脉活血汤治疗血栓闭塞性脉管炎30例", 《光明中医》 *
张奇文: "《中国当代名医验方选编 内科 》", 31 December 2014, 中国中医药出版社 *

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