CN108771661A - One plant sterols soft capsule of lycopene - Google Patents

Abstract

One plant sterols soft capsule of lycopene, including component A, component B and component C, the component A are raw material, are made of following active princlple：Lycopene, phytosterol, wherein the mass ratio of lycopene and phytosterol is 0.563 ± 0.065；The component B is auxiliary material, is made of following active princlple：Beeswax, lecithin, sunflower oil；The mass ratio of wherein phytosterol and sunflower oil is：0.3137±0.05；The component C is capsule skin, is made of following active princlple：Gelatin, glycerine, purified water, titanium dioxide, cacao pigment；Source of lycopene derives from phytosterol in the cupreol in lycopene grease, capsule.Unique formula of the invention improves the absorption rate of phytosterol, and phytosterol and lycopene are effectively combined, and improves the bioavailability of function factor, and promoting and applying has good economic and social benefit.

Description

One plant sterols soft capsule of lycopene

Technical field

The invention belongs to health products preparing technical fields, more particularly to a plant sterols soft capsule of lycopene, are applicable in In following occasion：The bioavailability of function factor is improved, prostate gland hyperplasia is prevented, removes free radical --- it is anti-oxidant, T, bone-marrow-derived lymphocyte and macrophage DNA, cell membrane is protected to be damaged from autoxidation；Promote T, B lymphocyte proliferation, stimulates T Cell function enhances cellular immune function, improves T cell and NK cell activity in human immune system, enhances macrophage Phagocytic activity improves humoral immunity and Cell-mediated Immunity, enhances human immunity；It slows down aging；Enhance capability of resistance to radiation；It adjusts Save blood fat；Improve male sterility；Promote female breast healthy development；Prevent and inhibit tumour.

Background technology

With the continuous development of national economy level, our country has entered an aging society the stage, the morbidity of various diseases The trend being gradually increasing is presented.Prostatic disorders are known as " number one killer of global men's health ".In China, prostatic disorders Incidence it is high, and with advancing age, incidence is higher and higher, while also apparent rejuvenation development becomes Gesture.For improve male health care consciousness and attention rate, 2000 the World Health Organization (WHO) determine that annual October 28 was " world's men's health day ".

According to medical literature：China 20 years old or more male chronic prostatitis illness rate is 31%~40%, 31-40 Sui Man in, the incidence of hyperplasia of prostate is 8%, lesser extent；It then increases sharply after 40 years old, in 51-60 Sui man Incidence is up to 50%；61-70 Sui this age is arrived, incidence can increase to 70% or more, and 80 years old or more elderly men In, 90% has hyperplasia of prostate.And there is 50-88% to suffer from benign prostatic hyperplasis in 60-80 Sui male.

Benign prostate hyperplasia (BPH) is to cause middle-aging male urination barrier property disease, barrier of urinating caused by the disease Hinder symptom, such as frequent micturition, urgent urination, uroflow are thin and delicate, urine retention drastically influences the quality of life of patient, being such as not treated in time can lead Cause many severe complications, such as acute urinary retention, stone in urinary system, renal insufficiency.

Benign prostatic hyperplasis (BPH) is elderly men common disease, after being more common in 50 years old, western countries 51-60 Sui Male, it is estimated that with BPH up to 42%, and 61-70 Sui male, with BPH up to 70%, 81-90 Sui almost 90% trouble There is BPH, similar to histological appearance, with the increase at age, the symptoms such as dysuria are consequently increased.About 50% tissue The male for learning diagnosis BPH has moderate to severe lower urinary tract symptom (LUTS).Some researches show that seem that Asian is more easy to compared with American In generation-severe BPH related symptoms.There are many patients BPH therefore not to seek medical advice and medicine, and BPH is but considered as aging on the contrary A part, so the illness rate of the disease is underestimated.

Www.xinhuanet.com's Shanghai channel message on October 31st, 2008：Prostatic disorders are male's common frdquently encountered diseases, in America and Europe etc. Country, incidence may be up to 80% or more in elderly men, and the country is slightly below America and Europe, but its incidence is also 50% or more. The common disease and frequently-occurring disease of adult male are had become at present, and incidence is in virile diesae first place.

Prostate cancer is malignant tumour common in American-European countries male, and in the U.S., prostate-cancer incidence accounts for male tumor The 1st, Europe be male tumor second, be only second to lung cancer.

There are following Three Difficult Issues for prostatosis：One), prostate lipid envelope can not penetrate, conventional medicament effective component Prostate lipid envelope cannot be penetrated, causes antibacterials to be difficult to reach effective Mlc into prostate, this is long The medicine wide gap that phase can not go beyond, and effective component is easy to be combined with hemoglobin, and drug effect, which weakens, even to be shielded, treatment, Lesion is repaired also just not know where to begin；Two), glandular tube blocking causes toxin cannot exclude, and germ constantly breeds raw toxin in glandular tube And purulent material makes ducts of prostate gland stick together, and becomes narrow.By fibrosis down to aging, virus puts aside object for gland tube wall tissue Eventually lead to the blocking of glandular tube.Harmful substance and toxin the stimulation prostate that long time sedimentation gets off are inflamed or even hyperplasia； Three) body of gland, can not be prevented to continue hyperplasia, traditional therapy is palliative, can not really control prgf Activity causes body of prostate still continuing to increase, and hidden danger is infinite, and the state of an illness constantly recurs, and symptom increasingly aggravates, and prostate increases Life easily leads to prostatic lesion.

Phytosterol (main component is cupreol), it is the cholesterol of plant to be otherwise known as, the work with norcholesterol With 5 alpha-reductases of inhibition convert testosterone to DHT, promote the estrogenic antagonist of prostate, also antiproliferative effect, energy Inhibit hyperplasia of prostate by inhibiting the secretion of a variety of growth factors in prostata tissue, and T cell activity, enhancing can be improved Body immunity, to achieve the purpose that treatment and prevention BPH (benign prostate hyperplasia).

In the treatment of European Countries Traditional Folk, used since ancient times to contain phytosterol extractant as before treating Row gland hypertrophy disease medicament.In recent years, it according to confirmation cupreol study on the efficiency report is carried out, is explicitly acted on though not yet confirming Mechanism, but think that cupreol has and inhibit hypertrophy of the prostate, improve bladder contraction and other effects.Now, Germany has confirmed that plant Sterol can be used as treatment prostate medication, and also there are many clinical researches for supporting the result of study for Japan.

Current research demonstrate phytosterol reduce blood cholesterol level, inhibit tumour, prevention hypertrophy of the prostate, The inhibition proliferation of mammary gland and adjusting are immune etc. all plays an important role.

Palmetto originates in Fla., is a kind of drug being widely used in treatment forefront adenoncus, ingredient Including phytosterol (mainly cupreol), zinc, selenium, VitAVitE, lycopene etc.；The Young in the U.S. The prevention hypertrophy of the prostate drug Better Prostate of Again Nutrition companies production, main composition are also Cupreol.

Phytosterol has certain positive effect to the incidence for reducing male prostate hypertrophy and prostate cancer.In Europe Continent, the preparation containing sitosterol have been used for the clinical treatment of hyperplasia of prostate.

Clinical research confirmation, the phytosterol for absorbing various dose have inhibition hypertrophy of the prostate and improve bladder contraction Effect is forced to frequent micturition, nocturnal pollakiuria, bladder, urination disorder symptom improves significantly effect.

Lycopene (lycopene) is the strongest natural class of inoxidizability being found in the plant of nature at present Carrotene, oxidation resistance are about 3.2 times of carrotene, 100 times of vitamin E, there is the good reputation of " plant gold ".Clear Except human body " source of ten thousand diseases " --- in terms of free radical, the effect of lycopene is more powerful than beta carotene, it is a kind of very strong Antioxidant has the ability of extremely strong removing free radical, has significantly to prevention prostate cancer, lung cancer, breast cancer, uterine cancer etc. Effect effectively inhibits the diffusion and duplication of cancer cell, also prevents cardiovascular and cerebrovascular disease, improves immunity, cell DNA is protected to exempt from By free radical damage, cytopathy, mutation, canceration are prevented；The active material of antioxidation biology containing strength, can promote cell growth and Regeneration, beautifying wrinkle-removing maintain skin health, slow down aging and other effects, there is the title of " plant gold ", is known as " 21 century health care The new lover of product ".

2003, the U.S.《Epoch》Magazine is listed in lycopene first of " contributing maximum food to human health ", kind Therefore Lycopene is also referred to as " gold in plant ", lycopene is connect in American-European, Japan and Chinese Hong Kong & Taiwan areas extensively By；There is special effect to prevention prostatic disorders, prostate cancer, lung cancer, gastric cancer, breast cancer, effectively inhibit the diffusion and duplication of cancer cell, It is known as " plant gold " by western countries.

Effect of the lycopene to human body：

1, prevent and cancer, newest research results is inhibited to show to absorb 30 milligrams of lycopenes daily, prevention can be reached The effect of the kinds cancers such as prostate cancer, digestive system cancer and carcinoma of urinary bladder.Human body can not synthesize lycopene, it is necessary to from diet Intake, eats the lycopene that a uncivilized nation eggplant can only absorb 0.05 milligram.Therefore, in the treatment of prostatic disorders, supplement kind Lycopene is essential；

2, protection is cardiovascular, during the occurrence and development of atherosclerosis, the lipoprotein oxidation in endangium It is a key factor.Lycopene plays an important role in terms of reducing lipoprotein oxidation.It is reported that oral natural tomato Red pigment, can make serum cholesterol be down to 5.20 mM/ls hereinafter, lycopene for preventing high cholesterol and hyperlipemia, The development of angiocardiopathy can be slowed down；

3, ultra-violet radiation resisting function, lycopene can be to ultraviolet injury resistants.Researcher respectively mends to 10 Healthy Peoples Fill 28 milligrams of beta carotenes and 2 milligrams lycopene 1-2 months, as a result take lycopene crowd's ultraviolet light and cause erythema Area is reduced, and degree mitigates；

4, inhibit mutagenesis, one of the important mechanisms that tumour generates are that histocyte is sent out under the action of extraneous mutagens Raw gene mutation, and lycopene can block this process, play antitumaous effect.If Mediterranean Region resident is in grillING fish and meat While use catsup, reduce the formation of the mutagens such as miscellaneous amine in gastronomical process.So while local resident's eating easily causes The grillING food of cancer, but the incidence of cervical carcinoma, prostate cancer and liver cancer is but very low；

5, it slows down aging, strengthen immunity, lycopene can most effectively remove the free radical in human body, keep cell Eubolism, it is pre- anti-aging.Lycopene is absorbed into blood and lymph by gastrointestinal mucosal in vivo, be distributed to testis, Adrenal gland, prostate, pancreas, breast, ovary, liver, lung, colon, skin and various mucosal tissues promote glandular secretion to swash Element, the energy to make human body keep vigorous；The free radical in these organs and tissue is removed, protects them from injuring, is increased Strong immunity of organisms；

6, improve skin allergy, lycopene can substantially improve skin allergy, eliminate because of caused by skin allergy Dry skin and scratchiness make us feeling relaxed happiness；

7, other multiple functions, lycopene are largely present in internal various mucous membrane tissues, long-term use can improve because Internal mucous membrane tissue destroys and the various discomforts of initiation, and if dry cough, eyes are dry and astringent, canker sore protects gastrointestinal tract mucosa tissue Deng.Lycopene can enable Infertil man sperm quantity increase, vigor enhances, to cure sterile problem.

Formula how is improved, the absorption rate of phytosterol is improved；How phytosterol and lycopene effectively to be tied It closes, improves the bioavailability of function factor, become urgent problem.

Invention content

The purpose of the present invention will solve above-mentioned technical problem.

The object of the present invention is achieved like this：One plant sterols soft capsule of lycopene, including component A, component B and Component C, it is characterised in that：The component A is raw material, is made of following active princlple：Lycopene, phytosterol, wherein The mass ratio of lycopene and phytosterol is 0.563 ± 0.065；

The component B is auxiliary material, is made of following active princlple：Beeswax, lecithin, sunflower oil；Wherein plant steroid The mass ratio of alcohol and sunflower oil is：0.3137±0.05；The mass ratio of sunflower oil and lecithin is：31.875 ± 2, lecithin The mass ratio of fat and beeswax is：0.667±0.01；

The component C is capsule skin, is made of following active princlple：Gelatin, glycerine, purified water, titanium dioxide, cocoa Shell color；

Source of lycopene derives from phytosterol in the cupreol in lycopene grease, capsule.

Unique formula of the invention effectively combines phytosterol and lycopene, nutrition comprehensively, ratio science, function because The bioavailability of son is high, and efficacy exertion ability is strong compared with common product, significant in efficacy；Easily it is absorbed by the body, absorption rate is high, Prostate lipid envelope is effectively broken through, glandular tube has been dredged, has eliminated toxin, effectively prevents glandular hyperplasia；It can capture Endogenic free radical directly plays antioxidation, and spontaneous gene mutation caused by preventing endogenous oxidant protects T, bone-marrow-derived lymphocyte and macrophage DNA, cell membrane are damaged from autoxidation, are promoted T, B lymphocyte proliferation, be have stimulated T Cell function enhances cellular immune function, improves T cell and NK cell activity in human immune system, enhances macrophage The phagocytic activity of cell, improves humoral immunity and Cell-mediated Immunity, and adjusting enhances body immunity；Effectively inhibit 5 α also Protoenzyme converts testosterone to DHT, promotes the estrogenic antagonist of prostate, also antiproliferative effect, can be by inhibition before The secretion of a variety of growth factors inhibits hyperplasia of prostate in row glandular tissue, to reach treatment and prevention BPH (benign prostates Hyperplasia disease) purpose；

Help to slow down aging；Help to enhance capability of resistance to radiation；Help to adjust blood fat；There is improvement to make male sterility With；Peomote the healthy development of female breast；Contribute to prevention and inhibits the generation of tumour；It promotes and applies with good Economic and social benefit.

Specific implementation mode

The invention will be further described below, but not as limitation of the present invention：

One plant sterols soft capsule of lycopene, including component A, component B and component C, the component A are raw material, It is made of following active princlple：Lycopene, phytosterol, wherein the mass ratio of lycopene and phytosterol be 0.563 ± 0.065；The component B is auxiliary material, is made of following active princlple：Beeswax, lecithin, sunflower oil；Wherein phytosterol Mass ratio with sunflower oil is：0.3137±0.05；The mass ratio of sunflower oil and lecithin is：31.875 ± 2, lecithin Mass ratio with beeswax is：0.667±0.01；The component C is capsule skin, is made of following active princlple：It is gelatin, sweet Oil, purified water, titanium dioxide, cacao pigment；Source of lycopene is derived from the cupreol in lycopene grease, capsule Phytosterol.Cupreol is a variety of growth factor activity inhibitor of efficient prostate, by human body to cupreol Intake, the root that cupreol active factors occur directly against prostatic disorders, bidirectional modulation prostatic lesion hyperplastic tissue, Inhibit the activity of prgf, improve prostate CD4 immunologic cellular activities, enhances prostate immune disease-resistance poison function, Fundamentally prevent the generation of prostatosis；Lycopene is a kind of very strong antioxidant, can most effectively remove human body Interior free radical protects cell DNA from free radical damage, keeps cell eubolism.Lycopene passes through digestion in vivo Road mucosa absorption enters blood and lymph, be distributed to testis, adrenal gland, prostate, pancreas, breast, ovary, liver, lung, colon, Skin and various mucosal tissues promote glandular secretion hormone, the energy to make human body keep vigorous；Remove these organs and Free radical in tissue protects them from injuring.

The capsule of unique formula of the invention, preparation has the characteristics that：

1) prostate lipid envelope, is broken through, the cupreol of capsule belongs to fat-soluble scintilla, more to prostate adipose membrane It is good to dissipate property, is absorbed by prostate organs histocyte by blood circulation, easily enter body of prostate and acts, carries significantly High penetrance of the cupreol efficacy factor to prostate lipid envelope；

2) it, dredged glandular tube, eliminated toxin, cupreol enters gland and stops interior directly activation prostate CD4 immunocytes, Restore the normal immune disease-resistance poison function of prostate, kills the germ in glandular tube one by one, swallow the aging fibr tissue on tube wall Cell, gland tube wall elasticity increase, and glandular tube diameter becomes larger, the tampers such as aging fibrous matter, prostatic secretion, virus in pipe It is constantly discharged, glandular tube becomes unblocked；

3) glandular hyperplasia, is prevented, cupreol is while inhibition prostate a variety of growth factor activities, acute activation Prostate CD4 immunocytes swallow the proliferation of fibrous tissue cell and epithelial tissue proliferative cell of aging in prostate, make forefront Gland does not continue to hyperplasia, and is gradually restored to normal；

4), protect prostatic cell DNA from free radical damage, lycopene is a kind of very strong antioxidant, can be with The free radical in human body is most effectively removed, protects cell DNA from free radical damage, keeps cell eubolism.Tomato red Element blood and lymph are absorbed by gastrointestinal mucosal in vivo, be distributed to testis, adrenal gland, prostate, pancreas, breast, Ovary, liver, lung, colon, skin and various mucosal tissues promote glandular secretion hormone, the essence to make human body keep vigorous Power；The free radical in these organs and tissue is removed, secondary injury is protected them from.

Unique formula of the invention effectively combines phytosterol and lycopene, nutrition comprehensively, ratio science, function because The bioavailability of son is high, and efficacy exertion ability is strong compared with common product, significant in efficacy；Easily it is absorbed by the body, absorption rate is high, Prostate lipid envelope is effectively broken through, glandular tube has been dredged, has eliminated toxin, effectively prevents glandular hyperplasia；It can capture Endogenic free radical directly plays antioxidation, and spontaneous gene mutation caused by preventing endogenous oxidant protects T, bone-marrow-derived lymphocyte and macrophage DNA, cell membrane are damaged from autoxidation, are promoted T, B lymphocyte proliferation, be have stimulated T Cell function enhances cellular immune function, improves T cell and NK cell activity in human immune system, enhances macrophage The phagocytic activity of cell, improves humoral immunity and Cell-mediated Immunity, and adjusting enhances body immunity；Effectively inhibit 5 α also Protoenzyme converts testosterone to DHT, promotes the estrogenic antagonist of prostate, also antiproliferative effect, can be by inhibition before The secretion of a variety of growth factors inhibits hyperplasia of prostate in row glandular tissue, to reach treatment and prevention BPH (benign prostates Hyperplasia disease) purpose.

The present invention helps to slow down aging；Help to enhance capability of resistance to radiation；Help to adjust blood fat；Have to male sterility Improvement result；Peomote the healthy development of female breast；Contribute to prevention and inhibits the generation of tumour.

The above embodiment of the present invention is only to clearly demonstrate examples of the invention, but be not limited to this hair Bright protection domain, all equivalent technical solutions also belong to scope of the invention, and scope of patent protection of the invention should be by each Item claim limits.

Claims (1)

1. a plant sterols soft capsule of lycopene, including component A, component B and component C, it is characterised in that：The component A is raw material, is made of following active princlple：Lycopene, phytosterol, wherein the mass ratio of lycopene and phytosterol It is 0.563 ± 0.065；

The component B is auxiliary material, is made of following active princlple：Beeswax, lecithin, sunflower oil；Wherein phytosterol with The mass ratio of sunflower oil is：0.3137±0.05；The mass ratio of sunflower oil and lecithin is：31.875 ± 2, lecithin with The mass ratio of beeswax is：0.667±0.01；

The component C is capsule skin, is made of following active princlple：Gelatin, glycerine, purified water, titanium dioxide, cocoa shell Color；

Source of lycopene derives from phytosterol in the cupreol in lycopene grease, capsule.