CN108744016A - A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory - Google Patents
A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory Download PDFInfo
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- CN108744016A CN108744016A CN201810846494.3A CN201810846494A CN108744016A CN 108744016 A CN108744016 A CN 108744016A CN 201810846494 A CN201810846494 A CN 201810846494A CN 108744016 A CN108744016 A CN 108744016A
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
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Abstract
The invention discloses a kind of preparation methods of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory, are related to field of nonwoven fabric technology, include the following steps：Medical non-woven fabrics is put into sodium hydroxide solution and is impregnated, is taken out, cleans to neutrality, press dry；The Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae are mixed, crushed, ethanol solution refluxing extraction is added, sodium alginate, anion surfactant and coconut oil are added into the filtrate after decoloration for filtering, decoloration, stirring, obtains complex liquid；Medical non-woven is arranged in complex liquid, ultrasound is impregnated, and is taken out, is pressed dry, it is dry to get.Non-woven fabrics of the present invention is after NaOH pretreatment, it is put into complex liquid, under the action of anion surfactant, active ingredient and sodium alginate can be deep into inside non-woven fabrics in Chinese medicine extract, non-woven fabrics bactericidal antiphlogistic obtained, moisture absorbing and sweat releasing, the drying property for keeping wound surface, promotes its healing.
Description
Technical field
The present invention relates to field of nonwoven fabric technology more particularly to a kind of preparation sides of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory
Method.
Background technology
Non-woven fabrics directly to utilize high polymer slice, staple fiber or long filament by fiber by air-flow or mechanical networking, and passes through
Process formed on-woven cloth, technological process is short, yield is high, at low cost, raw material sources are more, and with it is moisture-proof, ventilative,
Flexible, easy the features such as decomposing, is nontoxic nonirritant；Non-woven fabrics is main processing with polypropylene fibre, terylene, polyamide fibre, viscose rayon etc.
Raw material.Due to the excellent characteristic of non-woven fabrics and cheap processing cost, it is widely used in medical treatment, home decoration, clothes and work
The fields such as industry cloth.Non-woven fabrics is used in medical field, and traditional processing raw material is mostly Chemical fiber component, applied to wound dressing
Direct skin contact class product, will produce stimulation and injury to human skin, can only play the role of isolated environment and wrapping, though and
So play the role of completely cutting off bacterium, but most of non-woven fabrics does not have active bacteriostasis efficacy at present.
Invention content
Technical problems based on background technology, the present invention propose a kind of medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory
Preparation method, non-woven fabrics bactericidal antiphlogistic obtained, moisture absorbing and sweat releasing, keeps the drying property of wound surface.
A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory proposed by the present invention, includes the following steps：
(1) medical non-woven fabrics is put into sodium hydroxide solution and is impregnated, taken out, cleaned to neutrality, press dry；
(2) the Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae are mixed, is crushed, is added
Ethanol solution refluxing extraction filters, and sodium alginate, anion surfactant and coconut palm are added into the filtrate after decoloration for decoloration
Seed oil, stirring, obtains complex liquid；
(3) medical non-woven is arranged in complex liquid, ultrasound is impregnated, and is taken out, is pressed dry, it is dry to get.
Preferably, in step (1), medical non-woven fabrics is medical bamboo fiber spunlace non-woven cloth.
Preferably, it in step (1), is put into 4-8% sodium hydroxide solutions and impregnates 2-5h.
Preferably, in step (2), the fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae weight ratio be
7-14：7-14：7-14：5-10：5-10：7-14：7-14.
Preferably, in step (2), 4-7 times of 50-60% ethanol solution refluxing extractions 1-3h is added.
Preferably, in step (2), the sodium alginate for accounting for filtrate weight 4-8% respectively, 1- are added into the filtrate after decoloration
3% anion surfactant and the coconut oil of 3-5%.
Preferably, in step (2), anion surfactant is neopelex, lauryl sodium sulfate, two
It is one or more in octyl sulfosuccinate sodium.
Preferably, in step (3), ultrasound impregnates 40-60min, and ultrasonic temperature is 30-40 DEG C, ultrasonic power 300-
400W。
Advantageous effect：Medical non-woven fabrics is put into sodium hydroxide solution dipping by the present invention so that nonwoven surface is etched
Become coarse, improve its wettability of the surface, then places it in by Chinese medicine extract, sodium alginate, anion surfactant
With coconut oil compounding composition complex liquid in impregnate, wherein Chinese medicine extract be by the fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis,
Cape jasmine, the Chinese bulbul, Radix Glycyrrhizae mixing, what alcohol extracting obtained, have the function of clearing heat and detoxicating, bactericidal antiphlogistic, calmness, the alginic acid of addition
Sodium contains the hydrophilic radicals such as great amount of hydroxy group, amino, there is good hydrophily and hygroscopicity and antibacterial, itching-relieving efficacies, is added
Anion surfactant can be adsorbed on nonwoven surface, hydrophobic side and non-woven fabrics fiber combine and are attracted to surface,
The other end then stretches to the adsorption layer for being formed and being aligned in air, to change the wettability of nonwoven surface, improves its parent
It is aqueous, promote active ingredient and sodium alginate in Chinese medicine extract to be deep into inside non-woven fabrics, coordinate coconut oil, improves non-woven fabrics
Skin-friendly, non-woven fabrics bactericidal antiphlogistic obtained, moisture absorbing and sweat releasing keep the drying property of wound surface, promote its healing.
Specific implementation mode
In the following, technical scheme of the present invention is described in detail by specific embodiment.
Embodiment 1
A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory proposed by the present invention, includes the following steps：
(1) medical bamboo fiber spunlace non-woven cloth is put into 4% sodium hydroxide solution and impregnates 2h, taken out, cleaning to neutrality,
It press dry；
(2) by the Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae according to 7：7：14：5：
10：7：14 weight ratio mixing, crushes, 4 times of 50% ethanol solution refluxing extraction 1h is added, filter, decoloration, to after decoloration
The neopelex of the sodium alginate, 1% that account for filtrate weight 4% respectively and 5% coconut oil are added in filtrate, stirs
It mixes, obtains complex liquid；
(3) medical non-woven is arranged in complex liquid, ultrasound impregnates 40min, and ultrasonic temperature is 30 DEG C, and ultrasonic power is
300W takes out, press dry, it is dry to get.
Embodiment 2
A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory proposed by the present invention, includes the following steps：
(1) medical bamboo fiber spunlace non-woven cloth is put into 8% sodium hydroxide solution and impregnates 5h, taken out, cleaning to neutrality,
It press dry；
(2) by the Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae according to 14：14：7：
10：5：14：7 weight ratio mixing, crushes, 7 times of 60% ethanol solution refluxing extraction 3h is added, filter, decoloration, to after decoloration
Filtrate in the lauryl sodium sulfate of the sodium alginate, 3% that account for filtrate weight 8% respectively and 3% coconut oil is added, stir
It mixes, obtains complex liquid；
(3) medical non-woven is arranged in complex liquid, ultrasound impregnates 60min, and ultrasonic temperature is 40 DEG C, and ultrasonic power is
400W takes out, press dry, it is dry to get.
Embodiment 3
A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory proposed by the present invention, includes the following steps：
(1) medical bamboo fiber spunlace non-woven cloth is put into 5% sodium hydroxide solution and impregnates 3h, taken out, cleaning to neutrality,
It press dry；
(2) by the Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae according to 10：10：10：
8：8：10：10 weight ratio mixing, crushes, 5 times of 55% ethanol solution refluxing extraction 2h is added, filter, decoloration, to after decoloration
Filtrate in 6% sodium alginate, 2% sodium dioctyl sulfosuccinate and 4% coconut for accounting for filtrate weight respectively is added
Oil, stirring, obtains complex liquid；
(3) medical non-woven is arranged in complex liquid, ultrasound impregnates 45min, and ultrasonic temperature is 35 DEG C, and ultrasonic power is
350W takes out, press dry, it is dry to get.
Embodiment 4
A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory proposed by the present invention, includes the following steps：
(1) medical bamboo fiber spunlace non-woven cloth is put into 6% sodium hydroxide solution and impregnates 4h, taken out, cleaning to neutrality,
It press dry；
(2) by the Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae according to 8：12：10：7：
7：12：12 weight ratio mixing, crushes, 6 times of 60% ethanol solution refluxing extraction 2h is added, filter, decoloration, to after decoloration
The anion surfactant of the sodium alginate, 1.5% that account for filtrate weight 7% respectively and 4.5% coconut oil are added in filtrate,
Stirring, obtains complex liquid；Wherein, anion surfactant be by sodium dioctyl sulfosuccinate and lauryl sodium sulfate according to
2：1 weight ratio compounding composition；
(3) medical non-woven is arranged in complex liquid, ultrasound impregnates 50min, and ultrasonic temperature is 40 DEG C, and ultrasonic power is
400W takes out, press dry, it is dry to get.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (8)
1. a kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory, which is characterized in that include the following steps：
(1) medical non-woven fabrics is put into sodium hydroxide solution and is impregnated, taken out, cleaned to neutrality, press dry；
(2) the Chinese medicine material fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae are mixed, is crushed, ethyl alcohol is added
Solution refluxing extraction filters, and sodium alginate, anion surfactant and coconut oil are added into the filtrate after decoloration for decoloration,
Stirring, obtains complex liquid；
(3) medical non-woven is arranged in complex liquid, ultrasound is impregnated, and is taken out, is pressed dry, it is dry to get.
2. the preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory according to claim 1, which is characterized in that step
(1) in, medical non-woven fabrics is medical bamboo fiber spunlace non-woven cloth.
3. the preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory according to claim 1 or 2, which is characterized in that step
Suddenly it in (1), is put into 4-8% sodium hydroxide solutions and impregnates 2-5h.
4. according to the preparation method of the medical adhesive-bonded fabric dressing of any moisture absorption anti-inflammatory of claim 1-3, which is characterized in that
In step (2), the fruit of summer cypress, frutus cnidii, cordate houttuynia, the coptis, cape jasmine, the Chinese bulbul, Radix Glycyrrhizae weight ratio be 7-14：7-14：7-14：
5-10：5-10：7-14：7-14.
5. according to the preparation method of the medical adhesive-bonded fabric dressing of any moisture absorption anti-inflammatory of claim 1-4, which is characterized in that
In step (2), 4-7 times of 50-60% ethanol solution refluxing extractions 1-3h is added.
6. according to the preparation method of the medical adhesive-bonded fabric dressing of any moisture absorption anti-inflammatory of claim 1-5, which is characterized in that
In step (2), the anionic surface of the sodium alginate, 1-3% that account for filtrate weight 4-8% respectively is added into the filtrate after decoloration
The coconut oil of activating agent and 3-5%.
7. according to the preparation method of the medical adhesive-bonded fabric dressing of any moisture absorption anti-inflammatory of claim 1-6, which is characterized in that
In step (2), anion surfactant is neopelex, lauryl sodium sulfate, dioctyl succinic acid
It is one or more in sodium.
8. according to the preparation method of the medical adhesive-bonded fabric dressing of any moisture absorption anti-inflammatory of claim 1-7, which is characterized in that
In step (3), ultrasound impregnates 40-60min, and ultrasonic temperature is 30-40 DEG C, ultrasonic power 300-400W.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810846494.3A CN108744016A (en) | 2018-07-27 | 2018-07-27 | A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810846494.3A CN108744016A (en) | 2018-07-27 | 2018-07-27 | A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory |
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| Publication Number | Publication Date |
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| CN108744016A true CN108744016A (en) | 2018-11-06 |
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| CN201810846494.3A Pending CN108744016A (en) | 2018-07-27 | 2018-07-27 | A kind of preparation method of the medical adhesive-bonded fabric dressing of moisture absorption anti-inflammatory |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111962159A (en) * | 2020-08-27 | 2020-11-20 | 望江汇通纺织有限公司 | Cotton smashing device |
| CN113144037A (en) * | 2021-03-03 | 2021-07-23 | 上海沐芙乐医疗科技有限公司 | A skin external preparation based on PWP300 plant components for improving atopic dermatitis and infantile eczema |
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| CN103394012A (en) * | 2013-08-16 | 2013-11-20 | 李蓓 | Medical skin disinfection liquid |
| CN103933585A (en) * | 2014-04-24 | 2014-07-23 | 王庆华 | Medical disinfecting ultrasonic couplant and preparation method thereof |
| CN104758747A (en) * | 2015-04-23 | 2015-07-08 | 广西达庆生物科技有限公司 | Medicinal repairing dressing for treating viral skin disease and preparation method thereof |
| CN105903056A (en) * | 2016-06-02 | 2016-08-31 | 四川奎星医用高分子制品有限责任公司 | Medical composite alginate dressing containing analgesic drug and preparation method thereof |
| CN107029043A (en) * | 2017-04-28 | 2017-08-11 | 郑州人造金刚石及制品工程技术研究中心有限公司 | A kind of bactericidal antiphlogistic topical agent and preparation method thereof |
| CN108071008A (en) * | 2017-12-20 | 2018-05-25 | 合肥洁诺无纺布制品有限公司 | A kind of anti-inflammatory medical non-woven fabrics |
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2018
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394012A (en) * | 2013-08-16 | 2013-11-20 | 李蓓 | Medical skin disinfection liquid |
| CN103933585A (en) * | 2014-04-24 | 2014-07-23 | 王庆华 | Medical disinfecting ultrasonic couplant and preparation method thereof |
| CN104758747A (en) * | 2015-04-23 | 2015-07-08 | 广西达庆生物科技有限公司 | Medicinal repairing dressing for treating viral skin disease and preparation method thereof |
| CN105903056A (en) * | 2016-06-02 | 2016-08-31 | 四川奎星医用高分子制品有限责任公司 | Medical composite alginate dressing containing analgesic drug and preparation method thereof |
| CN107029043A (en) * | 2017-04-28 | 2017-08-11 | 郑州人造金刚石及制品工程技术研究中心有限公司 | A kind of bactericidal antiphlogistic topical agent and preparation method thereof |
| CN108071008A (en) * | 2017-12-20 | 2018-05-25 | 合肥洁诺无纺布制品有限公司 | A kind of anti-inflammatory medical non-woven fabrics |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111962159A (en) * | 2020-08-27 | 2020-11-20 | 望江汇通纺织有限公司 | Cotton smashing device |
| CN113144037A (en) * | 2021-03-03 | 2021-07-23 | 上海沐芙乐医疗科技有限公司 | A skin external preparation based on PWP300 plant components for improving atopic dermatitis and infantile eczema |
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