CN108721521A - 一种清热利尿的保健品的制备方法 - Google Patents
一种清热利尿的保健品的制备方法 Download PDFInfo
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- CN108721521A CN108721521A CN201810513809.2A CN201810513809A CN108721521A CN 108721521 A CN108721521 A CN 108721521A CN 201810513809 A CN201810513809 A CN 201810513809A CN 108721521 A CN108721521 A CN 108721521A
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Abstract
本申请公开了一种清热利尿的保健品的制备方法，称取赋形剂、竹叶心、蒲公英、菾菜根、蝉蜕、麦冬、水龙骨、菟丝子、乌梢蛇、马兜铃、大飞扬、大血藤、蒙花皮、焦白术和丹参；清热利尿，制备方法简单，成本低廉，可操作性强，对环境无公害，安全环保，健脾利湿，补脾养胃；生津益肺，崩解时间短，分解状态好，易吸收，起效快且没有发现明显的毒副作用；竹叶心和蒲公英产生协同作用，健脾润肺，清脑治昏、提升精力，预防痴呆，祛痰开窍；药方中各个组分之间产生协同作用，从而带来清热利尿、精力充沛，用于小便黄短、阳痿遗精、精血不足、失眠多梦和咳嗽痰多，可以广泛生产并不断代替现有材料。
Description
技术领域
本申请属于保健品领域，尤其涉及一种清热利尿的保健品的制备方法。
背景技术
保健品食品的通俗说法。GB16740-97《保健（功能）食品通用标准》第3.1条将保健食品定义为：“保健（功能）食品是食品的一个种类，具有一般食品的共性，能调节人体的机能，适用于特定人群食用，但不以治疗疾病为目的。”所以在产品的宣传上，也不能出现有效率、成功率等相关的词语。 保健食品的保健作用在当今的社会中，也正在逐步被广大群众所接受。
市场上的保健品大体可以分为一般保健食品、保健药品、保健化妆品、保健用品等。保健食品具有食品性质，如茶、酒、蜂制品、饮品、汤品、鲜汁、药膳等，具有色、香、形、质要求，一般在剂量上无要求；保健药品具有营养性、食物性天然药品性质，应配合治疗使用，有用法用量要求，目前带“健”字批号的药品；保健化妆品具有化妆品的性质，不仅有局部小修饰作用，且有透皮吸收、外用内效作用，如保健香水、霜膏、漱口水等；保健用品具有日常生活用品的性质，如健身器、按摩器、磁水器、健香袋、衣服鞋帽、垫毯等。随着大家健康保健意识的不断增强，保健食品市场也空前的火爆起来。火爆的市场中，各种产品的质量也是参差不齐。接下来就教给大家如何挑选正规合适的保健食品。
由于大部分保健食品的设计是依据中医药理论和中医养生思想，科学组方配伍而成的，虽然申报的可能是27项功能中的同一个功能，但由于组方不同、原理不同，甚至配伍剂量不同、原料来源不同、工艺剂型不同,均可能对人体的健康产生不同的影响和作用，而且在不同人群（年龄、性别、职业、身体状况、生活区域、生活环境、生活方式）当中也会有不同的体现，这种同一保健功能却有不同人体作用效果的事实，需要在上市后通过循证医学研究加以产品作用和用差异化的客观评价。这既是为了真实而准确地反映出不同产品同一保健功能的效果不同于使用价值，也是为了广大消费者能够从中了解到真实的产品功能信息，以便掌握正确产品的人体适用性。
保健食品在欧美称“保健食品”或“健康食品”，也称营养食品，德国称“改良食品”，日本先称“功能性食品”，1990年改为“特定保健用食品”，并纳入“特定营养食品”范畴。世界各国对保健食品的开发都非常重视，新功能、新产品、新造型和新的食用方法不断出现。设计一种安全性高、崩解时间短，分解状态好，易吸收，起效快且没有发现明显的毒副作用的清热利尿的保健品的制备方法是非常必要的。
发明内容
解决的技术问题：
本申请针对上述技术问题，提供一种清热利尿的保健品的制备方法，解决现有保健品清热利尿效果差、崩解时间长和不易吸收等技术问题。
技术方案：
一种清热利尿的保健品的制备方法，包括如下步骤：
第一步：按照重量份数配比称取赋形剂100份、竹叶心5-15份、蒲公英1-3份、菾菜根11-15份、蝉蜕4-8份、麦冬6-10份、水龙骨5-9份、菟丝子3-7份、乌梢蛇1-5份、马兜铃2-6份、大飞扬2.5-6.5份、大血藤4-8份、蒙花皮2-4份、焦白术8-12份和丹参8-10份；
第二步：将净制、切制后的菾菜根、水龙骨和丹参按照2010年版一部中国药典附录IID的蒸法，制成饮片；
第三步：将大血藤、蝉蜕、大飞扬、乌梢蛇、蒙花皮和焦白术，用乙醇做溶剂，浸渍28-32h，渗滤后浓缩成浸膏；
第四步：将麦冬、竹叶心、蒲公英、菟丝子和马兜铃晒干，粉碎后过100目筛，与第二步制得的饮片和第三步制得的浸膏混合均匀，混合均匀后加入赋形剂，再加入水润湿后制成混合均匀的稠膏；
第五步：将稠膏干燥后粉碎干法制粒机做成颗粒，控制颗粒的水分在3-7%，制成颗粒剂、胶囊剂或者压制成片。
作为本发明的一种优选技术方案：所述赋形剂为甘露醇或环糊精中的一种或多种混合物。
作为本发明的一种优选技术方案：所述第一步中清热利尿的保健品的原料按重量份数配比如下：赋形剂100份、竹叶心5份、蒲公英1份、菾菜根11份、蝉蜕4份、麦冬6份、水龙骨5份、菟丝子3份、乌梢蛇1份、马兜铃2份、大飞扬2.5份、大血藤4份、蒙花皮2份、焦白术8份和丹参8份。
作为本发明的一种优选技术方案：所述第一步中清热利尿的保健品的原料按重量份数配比如下：赋形剂100份、竹叶心15份、蒲公英3份、菾菜根15份、蝉蜕8份、麦冬10份、水龙骨9份、菟丝子7份、乌梢蛇5份、马兜铃6份、大飞扬6.5份、大血藤8份、蒙花皮4份、焦白术2份和丹参10份。
作为本发明的一种优选技术方案：所述第一步中清热利尿的保健品的原料按重量份数配比如下：赋形剂100份、竹叶心10份、蒲公英2份、菾菜根13份、蝉蜕6份、麦冬8份、水龙骨7份、菟丝子5份、乌梢蛇3份、马兜铃4份、大飞扬4.5份、大血藤6份、蒙花皮3份、焦白术10份和丹参9份。
有益效果：
本发明所述一种清热利尿的保健品的制备方法采用以上技术方案与现有技术相比，具有以下技术效果：1、清热利尿，制备方法简单，成本低廉，可操作性强，对环境无公害，安全环保，健脾利湿，补脾养胃；2、生津益肺，崩解时间短，分解状态好，易吸收，起效快且没有发现明显的毒副作用；3、竹叶心和蒲公英产生协同作用，健脾润肺，清脑治昏、提升精力，预防痴呆，祛痰开窍；4、药方中各个组分之间产生协同作用，从而带来清热利尿、精力充沛，用于小便黄短、阳痿遗精、精血不足、失眠多梦和咳嗽痰多，可以广泛生产并不断代替现有材料。
具体实施方式
实施例1:
按照重量份数配比称取赋形剂100份、竹叶心5份、蒲公英1份、菾菜根11份、蝉蜕4份、麦冬6份、水龙骨5份、菟丝子3份、乌梢蛇1份、马兜铃2份、大飞扬2.5份、大血藤4份、蒙花皮2份、焦白术8份和丹参8份。
将净制、切制后的菾菜根、水龙骨和丹参按照2010年版一部中国药典附录IID的蒸法，制成饮片。
将大血藤、蝉蜕、大飞扬、乌梢蛇、蒙花皮和焦白术，用乙醇做溶剂，浸渍28h，渗滤后浓缩成浸膏。
将麦冬、竹叶心、蒲公英、菟丝子和马兜铃晒干，粉碎后过100目筛，与第二步制得的饮片和第三步制得的浸膏混合均匀，混合均匀后加入赋形剂，再加入水润湿后制成混合均匀的稠膏。
将稠膏干燥后粉碎干法制粒机做成颗粒，控制颗粒的水分在3%，制成颗粒剂、胶囊剂或者压制成片。
清热利尿，制备方法简单，成本低廉，可操作性强，对环境无公害，安全环保，健脾利湿，补脾养胃；生津益肺，崩解时间短，分解状态好，易吸收，起效快且没有发现明显的毒副作用；竹叶心和蒲公英产生协同作用，健脾润肺，清脑治昏、提升精力，预防痴呆，祛痰开窍；药方中各个组分之间产生协同作用，从而带来清热利尿、精力充沛，用于小便黄短、阳痿遗精、精血不足、失眠多梦和咳嗽痰多，可以广泛生产并不断代替现有材料。
实施例2:
按照重量份数配比称取赋形剂100份、竹叶心15份、蒲公英3份、菾菜根15份、蝉蜕8份、麦冬10份、水龙骨9份、菟丝子7份、乌梢蛇5份、马兜铃6份、大飞扬6.5份、大血藤8份、蒙花皮4份、焦白术2份和丹参10份。
将净制、切制后的菾菜根、水龙骨和丹参按照2010年版一部中国药典附录IID的蒸法，制成饮片。
将大血藤、蝉蜕、大飞扬、乌梢蛇、蒙花皮和焦白术，用乙醇做溶剂，浸渍32h，渗滤后浓缩成浸膏。
将麦冬、竹叶心、蒲公英、菟丝子和马兜铃晒干，粉碎后过100目筛，与第二步制得的饮片和第三步制得的浸膏混合均匀，混合均匀后加入赋形剂，再加入水润湿后制成混合均匀的稠膏。
将稠膏干燥后粉碎干法制粒机做成颗粒，控制颗粒的水分在7%，制成颗粒剂、胶囊剂或者压制成片。
清热利尿，制备方法简单，成本低廉，可操作性强，对环境无公害，安全环保，健脾利湿，补脾养胃；生津益肺，崩解时间短，分解状态好，易吸收，起效快且没有发现明显的毒副作用；竹叶心和蒲公英产生协同作用，健脾润肺，清脑治昏、提升精力，预防痴呆，祛痰开窍；药方中各个组分之间产生协同作用，从而带来清热利尿、精力充沛，用于小便黄短、阳痿遗精、精血不足、失眠多梦和咳嗽痰多，可以广泛生产并不断代替现有材料。
实施例3:
按照重量份数配比称取赋形剂100份、竹叶心10份、蒲公英2份、菾菜根13份、蝉蜕6份、麦冬8份、水龙骨7份、菟丝子5份、乌梢蛇3份、马兜铃4份、大飞扬4.5份、大血藤6份、蒙花皮3份、焦白术10份和丹参9份。
将净制、切制后的菾菜根、水龙骨和丹参按照2010年版一部中国药典附录IID的蒸法，制成饮片。
将大血藤、蝉蜕、大飞扬、乌梢蛇、蒙花皮和焦白术，用乙醇做溶剂，浸渍30h，渗滤后浓缩成浸膏。
将麦冬、竹叶心、蒲公英、菟丝子和马兜铃晒干，粉碎后过100目筛，与第二步制得的饮片和第三步制得的浸膏混合均匀，混合均匀后加入赋形剂，再加入水润湿后制成混合均匀的稠膏。
将稠膏干燥后粉碎干法制粒机做成颗粒，控制颗粒的水分在5%，制成颗粒剂、胶囊剂或者压制成片。
清热利尿，制备方法简单，成本低廉，可操作性强，对环境无公害，安全环保，健脾利湿，补脾养胃；生津益肺，崩解时间短，分解状态好，易吸收，起效快且没有发现明显的毒副作用；竹叶心和蒲公英产生协同作用，健脾润肺，清脑治昏、提升精力，预防痴呆，祛痰开窍；药方中各个组分之间产生协同作用，从而带来清热利尿、精力充沛，用于小便黄短、阳痿遗精、精血不足、失眠多梦和咳嗽痰多，可以广泛生产并不断代替现有材料。
典型例：以300例小便黄短、阳痿遗精、精血不足、失眠多梦患者为例，男180例，女120例，最大年龄95岁，最小年龄5岁，病程6个月至3年不等。
口服，一日1-4次，一次1-4片，连续服用3-7天有效率99%，继续使用10-14天，治愈率85%，连续服用20-30天，有效率99.9%，治愈率99%。
以上实施例中的配方所有药材均可以商业购买。
上述实施例只是用于对本发明的内容进行阐述，而不是限制，因此在与本发明的权利要求书相当的含义和范围内的任何改变，都应该认为是包括在权利要求书的范围内。
Claims (5)
1.一种清热利尿的保健品的制备方法，其特征在于，包括如下步骤：
第一步：按照重量份数配比称取赋形剂100份、竹叶心5-15份、蒲公英1-3份、菾菜根11-15份、蝉蜕4-8份、麦冬6-10份、水龙骨5-9份、菟丝子3-7份、乌梢蛇1-5份、马兜铃2-6份、大飞扬2.5-6.5份、大血藤4-8份、蒙花皮2-4份、焦白术8-12份和丹参8-10份；
第二步：将净制、切制后的菾菜根、水龙骨和丹参按照2010年版一部中国药典附录IID的蒸法，制成饮片；
第三步：将大血藤、蝉蜕、大飞扬、乌梢蛇、蒙花皮和焦白术，用乙醇做溶剂，浸渍28-32h，渗滤后浓缩成浸膏；
第四步：将麦冬、竹叶心、蒲公英、菟丝子和马兜铃晒干，粉碎后过100目筛，与第二步制得的饮片和第三步制得的浸膏混合均匀，混合均匀后加入赋形剂，再加入水润湿后制成混合均匀的稠膏；
第五步：将稠膏干燥后粉碎干法制粒机做成颗粒，控制颗粒的水分在3-7%，制成颗粒剂、胶囊剂或者压制成片。
2.根据权利要求1所述的一种清热利尿的保健品的制备方法，其特征在于：所述赋形剂为甘露醇或环糊精中的一种或多种混合物。
3.根据权利要求1所述的一种清热利尿的保健品的制备方法，其特征在于：所述第一步中清热利尿的保健品的原料按重量份数配比如下：赋形剂100份、竹叶心5份、蒲公英1份、菾菜根11份、蝉蜕4份、麦冬6份、水龙骨5份、菟丝子3份、乌梢蛇1份、马兜铃2份、大飞扬2.5份、大血藤4份、蒙花皮2份、焦白术8份和丹参8份。
4.根据权利要求1所述的一种清热利尿的保健品的制备方法，其特征在于：所述第一步中清热利尿的保健品的原料按重量份数配比如下：赋形剂100份、竹叶心15份、蒲公英3份、菾菜根15份、蝉蜕8份、麦冬10份、水龙骨9份、菟丝子7份、乌梢蛇5份、马兜铃6份、大飞扬6.5份、大血藤8份、蒙花皮4份、焦白术2份和丹参10份。
5.根据权利要求1所述的一种清热利尿的保健品的制备方法，其特征在于：所述第一步中清热利尿的保健品的原料按重量份数配比如下：赋形剂100份、竹叶心10份、蒲公英2份、菾菜根13份、蝉蜕6份、麦冬8份、水龙骨7份、菟丝子5份、乌梢蛇3份、马兜铃4份、大飞扬4.5份、大血藤6份、蒙花皮3份、焦白术10份和丹参9份。
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