CN108709857A - Pepsin detects capsule, detecting system and detection method - Google Patents
Pepsin detects capsule, detecting system and detection method Download PDFInfo
- Publication number
- CN108709857A CN108709857A CN201810217426.0A CN201810217426A CN108709857A CN 108709857 A CN108709857 A CN 108709857A CN 201810217426 A CN201810217426 A CN 201810217426A CN 108709857 A CN108709857 A CN 108709857A
- Authority
- CN
- China
- Prior art keywords
- capsule
- light transmission
- pepsin
- transmission piece
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 66
- 239000002775 capsule Substances 0.000 title claims abstract description 58
- 102000057297 Pepsin A Human genes 0.000 title claims abstract description 56
- 108090000284 Pepsin A Proteins 0.000 title claims abstract description 56
- 229940111202 pepsin Drugs 0.000 title claims abstract description 56
- 230000005540 biological transmission Effects 0.000 claims abstract description 57
- 238000006243 chemical reaction Methods 0.000 claims abstract description 32
- 238000002835 absorbance Methods 0.000 claims abstract description 12
- 210000002784 stomach Anatomy 0.000 claims description 17
- 238000004891 communication Methods 0.000 claims description 14
- 210000004051 gastric juice Anatomy 0.000 claims description 12
- 238000007789 sealing Methods 0.000 claims description 6
- 230000008054 signal transmission Effects 0.000 claims description 6
- 238000007689 inspection Methods 0.000 claims description 4
- 239000010453 quartz Substances 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 230000004060 metabolic process Effects 0.000 claims description 3
- 230000013011 mating Effects 0.000 claims 1
- 238000009738 saturating Methods 0.000 claims 1
- 238000012360 testing method Methods 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 238000003745 diagnosis Methods 0.000 description 6
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 229940088598 enzyme Drugs 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 208000018556 stomach disease Diseases 0.000 description 4
- 208000005718 Stomach Neoplasms Diseases 0.000 description 3
- 210000002318 cardia Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 206010017758 gastric cancer Diseases 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 201000011549 stomach cancer Diseases 0.000 description 3
- 230000008033 biological extinction Effects 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000004885 white matter Anatomy 0.000 description 2
- 208000007882 Gastritis Diseases 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 206010054949 Metaplasia Diseases 0.000 description 1
- 108010047320 Pepsinogen A Proteins 0.000 description 1
- 101710089165 Protein white Proteins 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000000090 biomarker Substances 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000012460 protein solution Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
Abstract
The present invention proposes that a kind of pepsin detects capsule, detecting system and detection method, the capsule includes capsule ontology, capsule ontology includes shell and its interior upper layer light transmission piece, lower layer's light transmission piece, it is formed with reaction chamber between the upper layer light transmission piece, lower layer's light transmission piece, and the cavity wall of upper layer light transmission piece, lower layer's light transmission piece as the reaction chamber, there is connection reaction chamber and the via outside shell on shell, and be provided with the biological semi-permeable film for covering the via in the reaction cavity wall；There is light source generator facing each other, detection transmitter in shell, and the light source generator, detection transmitter point on the outside of upper layer light transmission piece, lower layer's light transmission piece and one by one face, and there is monochromator between the light source generator and upper layer light transmission piece, transmitter output end connection signal receiving unit input terminal is detected, which is simultaneously sent to signal receiving unit by detection transmitter detection absorbance.Pepsin detection capsule structure is simple, and production cost is low, improves test result accuracy.
Description
Technical field
The present invention relates to medical instruments fields, and in particular to a kind of pepsin detection capsule, detecting system and detection side
Method.
Background technology
Pepsin in gastric juice has become the Biomarkers of gastritis, gastric cancer class disease.When intestinal metaplasia, it is not true to type
When hyperplasia and gastric cancer, pepsinia can be reduced, if infecting helicobacter pylori or having the diseases such as gastric ulcer, duodenal ulcer
Disease, stomach cardia enzyme values increase.
Currently, according to the relationship of a large amount of statistical analysis Serum Pepsinogen changes of contents and disease of stomach, it is believed that serum
The detection of propepsin plays an important roll in early gastric caacer diagnosis.This kind of mode mainly passes through the serum of acquisition subject
It is analyzed, but this method is internal collecting sample, is detected in vitro to analyze the concrete content of pepsin.Therefore,
Surveyed pepsin detects for single, has limitation for stomach cardia content in real time monitoring gastric juice；In addition, pepsin is only
It plays a role in acidic environment, pH > 6 lose activity, and are easy to be influenced to cause test result by environment under environment in vitro
It is inaccurate.
The diagnosis of gastric cancer and other disease of stomach at present still relies upon gastroscope and serum collection vitro detection to make a definite diagnosis, but gastroscope
Inspection has certain pain, and costly, is influenced by doctor's level, is not often received by patient, and Virus monitory exists not
Accuracy.
Invention content
In order to overcome above-mentioned defect existing in the prior art, the object of the present invention is to provide a kind of detection accuracy is high
Pepsin detects capsule, detecting system and detection method.
In order to realize the above-mentioned purpose of the present invention, the present invention provides a kind of pepsins to detect capsule, including capsule sheet
Body, the capsule ontology include shell and its interior upper layer light transmission piece, lower layer's light transmission piece, the upper layer light transmission piece, lower layer's light transmission piece
Between be formed with reaction chamber, and the cavity wall of upper layer light transmission piece, lower layer's light transmission piece as the reaction chamber, have on the shell and connect
Lead to the reaction chamber and the via outside shell, and is provided with the biological semi-permeable film for covering the via in the reaction cavity wall；It is described
There is light source generator facing each other, detection transmitter, and the light source generator, detection transmitter point are in described in shell
On the outside of upper layer light transmission piece, lower layer light transmission piece and one by one face, and there is monochromator between the light source generator and upper layer light transmission piece,
The detection transmitter output end connection signal receiving unit input terminal, the detection transmitter detect absorbance and by the extinctions
Degree is sent to signal receiving unit.
Pepsin is by entering the degradable egg in reaction chamber, with reaction chamber in gastric juice after via and biological semi-permeable film
White matter is reacted, and product can be to having selection index system by a certain special wavelength light after decomposition, and the light that light source generator is sent out is logical
Parallel and the light transmission of vertical irradiation upper layer, lower layer's light transmission piece monochromatic light is converted to after crossing monochromator, after the monochromatic light is by decomposition
Product rear portion is absorbed.It detects transmitter and detects absorbance, due to the concentration and absorption thickness of absorbance and extinction material
It spends directly proportional, pepsin content in gastric juice is obtained according to conventionally known algorithm.
Pepsin detection capsule structure is simple, and production cost is low, can be carried out to pepsin content in gastric juice continuous
It measures, the variation of pepsin content in gastric juice can be analyzed, greatly improve the accuracy of test result, while patient's inspection can be mitigated
The pain looked into is of great significance to each stomach class medical diagnosis on disease in clinic.
Further, there is the first cavity, the second cavity, first cavity, the second cavity to be in described in the shell
Reaction chamber both ends, wherein lower layer's light transmission piece forms first cavity with the shell one end inner wall；Lower layer's light transmission
Piece forms the reaction chamber with the shell other end inner wall；Second cavity is in the reaction chamber and is positioned at described
On shell, the upper layer light transmission piece is set in the second cavity cavity wall.This is simple in structure, and the inside of capsule is more rationally utilized
Space is readily produced.
Further, the number of vias is at least one, is located at the intersection inner wall of the reaction chamber, shell, and should
The biological semi-permeable film is set on intersection inner wall.
Further, the shell is the cylinder-like structure of sealing two ends, and second cavity is in the cylinder of sealing two ends
Shape structure, and second cavity is connected with the shell one end portion, wherein second cavity is set with the shell with central shaft
It sets.The design structure is simple, is readily produced, and is swallowed when improving the accuracy of detection, while also patient being facilitated to conduct a survey.
Further, the detection transmitter includes detection unit and signal transmitter unit, and the detection unit detection is inhaled
Luminosity, output end connect the signal transmission unit input terminal, and the signal transmission unit connects the signal receiving unit.
Further, the upper layer light transmission piece, lower layer's light transmission piece are quartz plate, and quartz plate thang-kng performance is good, improves
The accuracy of detection.
The invention also provides a kind of pepsin detecting system detecting capsule based on above-mentioned pepsin, including it is upper
Pepsin detection capsule, signal receiving unit and intelligent terminal are stated, the pepsin detection capsule is received with the signal
Unit communication connects, and the signal receiving unit is connect with intelligent terminal, the stomach egg that the pepsin detection capsule is detected
White enzyme content is sent to the intelligent terminal by signal receiving unit and is recorded, shows.The detecting system is simple in structure, raw
Produce into low, testing result accuracy height.
The invention also provides a kind of pepsin detection methods based on above-mentioned pepsin detecting system, including with
Under several steps：
The pepsin is placed in gastric juice by S1, if using communication, by feeder by the glue
Capsule is sent into stomach and is fixed, if using wired communication mode, the capsule is directly swallowed stomach, then consolidate to it
It is fixed；
S2, the pepsin detection capsule detects pepsin content, and timing detects capsule by the pepsin
In detection transmitter send detection data to the signal receiving unit, detection data is sent to by the signal receiving unit
The intelligent terminal is recorded, is shown；
S3 after detection, if it is communication, directly excludes capsule according to human stomach's metabolism
In vitro；If it is wired communication mode, directly capsule is taken out by transmission line.
The detection method is simple and practicable, can continuously be detected, and external interference is not easily susceptible to, and testing result accuracy is high,
The variation that pepsin content in gastric juice can be analyzed is of great significance for the diagnosis of disease of stomach.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obviously, or practice through the invention is recognized.
Description of the drawings
The above-mentioned and/or additional aspect and advantage of the present invention will become in the description from combination following accompanying drawings to embodiment
Obviously and it is readily appreciated that, wherein：
Fig. 1 is the structural schematic diagram of the present invention.
Specific implementation mode
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end
Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached
The embodiment of figure description is exemplary, and is only used for explaining the present invention, and is not considered as limiting the invention.
In the description of the present invention, unless otherwise specified and limited, it should be noted that term " installation ", " connected ",
" connection " shall be understood in a broad sense, for example, it may be mechanical connection or electrical connection, can also be the connection inside two elements, it can
, can also indirectly connected through an intermediary, for the ordinary skill in the art to be to be connected directly, it can basis
Concrete condition understands the concrete meaning of above-mentioned term.
As shown in Figure 1, the present invention provides a kind of pepsins to detect capsule, including capsule ontology, the capsule ontology
Including shell 1 and its interior upper layer light transmission piece 6, lower layer's light transmission piece 5, it is formed between the upper layer light transmission piece 6, lower layer's light transmission piece 5
Reaction chamber 8, and the cavity wall of upper layer light transmission piece 6, lower layer's light transmission piece 5 as the reaction chamber 8 have connection institute on the shell 1
Reaction chamber 8 and the via 2 outside shell 1 are stated, and is provided with the biological semi-permeable film 9 for covering the via 2 in 8 inner wall of reaction chamber.
2 quantity of the via is at least one, is located at the intersection inner wall of the reaction chamber 8, shell 1, and in the intersection
The biological semi-permeable film 9 is set on wall.
There is light source generator 11 facing each other, detection transmitter 4, and the light source generator 11, inspection in the shell 1
Transmitter 4 is surveyed to divide in the upper layer light transmission piece 6, the outside of lower layer's light transmission piece 5 and face one by one, and the light source generator 11 with it is upper
There is monochromator 7,4 output end connection signal receiving unit input terminal of the detection transmitter, the detection between layer light transmission piece 6
Transmitter 4 detects absorbance and the absorbance is sent to signal receiving unit.
Wired connection mode can be used with signal receiving unit in detection transmitter 4, and radio connection can also be used.When adopting
When with radio connection, capsule feeding stomach need to be fixed with specific feeder, then takes out feeder,
Feeder is not the key protection point of the application, and and will not be described here in detail, can refer to existing technical solution and is understood.Work as use
When wired connection mode, then capsule is directly swallowed into stomach, then it is fixed, so that signal receives.
Here detection transmitter 4 includes detection unit and signal transmitter unit, and the detection unit detects absorbance,
Output end connects the signal transmission unit input terminal, and the signal transmission unit connects the signal receiving unit.
Due to offering via 2 on the shell of the capsule, pepsin in gastric juice is allowed to be directly entered and by biology half
Permeable membrane 9 enters in reaction chamber 8, and degradable protein solution is filled in reaction chamber 8.When being detected, light source generator 11 is sent out
Light parallel and vertical irradiation upper layer light transmission 6, lower layer's light transmission piece 5 monochromatic light is converted to by monochromator 7, which passes through
After the color products that substrate protein white matter is formed after decomposing, a part is absorbed.Absorbance can be measured by detecting transmitter 4, and
Electric signal is converted optical signal into according to absorbance, the signal receiving unit of reception device is then forwarded to, directly displays stomach cardia
Enzyme content.
Wherein, there is the first cavity 3, the second cavity 10, first cavity 3, the second cavity 10 are in institute in the shell 1
State 8 both ends of reaction chamber, wherein lower layer's light transmission piece 5 forms first cavity 3 with 1 one end inner wall of the shell；Under described
Layer light transmission piece 5 forms the reaction chamber 8 with 1 other end inner wall of the shell；Second cavity 10 is in the reaction chamber 8
And be positioned on the shell 1, the upper layer light transmission piece 6 is set in 10 cavity wall of the second cavity.Preferably, upper layer light transmission piece 6,
Lower layer's light transmission piece 5 is preferably but not limited to as quartz plate.
To keep detection result more accurate, also allowing for patient and swallow, the shell 1 is the cylinder-like structure of sealing two ends,
Second cavity 10 is in the cylinder-like structure of sealing two ends, and second cavity 10 is connected with 1 one end of the shell,
In, second cavity 10 is arranged with the shell 1 with central shaft.
The invention also provides a kind of pepsin detecting system detecting capsule based on above-mentioned pepsin, including it is upper
Pepsin detection capsule, signal receiving unit and intelligent terminal are stated, the pepsin detection capsule is received with the signal
Unit communication connects, and the signal receiving unit is connect with intelligent terminal, the stomach egg that the pepsin detection capsule is detected
White enzyme content is sent to the intelligent terminal by signal receiving unit and is recorded, shows.
The invention also provides a kind of pepsin detection methods based on above-mentioned pepsin detecting system, including with
Under several steps：
The pepsin is placed in gastric juice by S1, if using communication, by feeder by the glue
Capsule is sent into stomach and is fixed, if using wired communication mode, the capsule is directly swallowed stomach, then consolidate to it
It is fixed；
S2, the pepsin detection capsule detects pepsin content, and timing detects capsule by the pepsin
In detection transmitter send detection data to the signal receiving unit, detection data is sent to by the signal receiving unit
The intelligent terminal is recorded, is shown；
S3 after detection, if it is communication, directly excludes capsule according to human stomach's metabolism
In vitro；If it is wired communication mode, directly capsule is taken out by transmission line.
Intelligent terminal can be according to the variation of pepsin content in received data analysis gastric juice, for disease of stomach
Diagnosis be of great significance.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
Centainly refer to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be any
One or more embodiments or example in can be combined in any suitable manner.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that：Not
In the case of being detached from the principle of the present invention and objective a variety of change, modification, replacement and modification can be carried out to these embodiments, this
The range of invention is limited by claim and its equivalent.
Claims (8)
1. a kind of pepsin detects capsule, including capsule ontology, it is characterised in that：The capsule ontology include shell (1) and
Upper layer light transmission piece (6), lower layer's light transmission piece (5) in it, the upper layer light transmission piece (6), lower layer's light transmission piece are formed with reaction between (5)
Chamber (8), and the cavity wall of upper layer light transmission piece (6), lower layer's light transmission piece (5) as the reaction chamber (8) have on the shell (1)
It is connected to the reaction chamber (8) and the via (2) of shell (1) outside, and is provided in reaction chamber (8) inner wall and covers the via (2)
Biological semi-permeable film (9)；There is light source generator (11) facing each other, detection transmitter (4), and should in the shell (1)
Light source generator (11), detection transmitter (4) point are on the outside of the upper layer light transmission piece (6), lower layer's light transmission piece (5) and one by one just
It is right, and there is monochromator (7), detection transmitter (4) output end between the light source generator (11) and upper layer light transmission piece (6)
Connection signal receiving unit input terminal, the detection transmitter (4) detect absorbance and the absorbance are sent to signal and receive
Unit.
2. pepsin according to claim 1 detects capsule, it is characterised in that：There is the first chamber in the shell (1)
Body (3), the second cavity (10), first cavity (3), the second cavity (10) are in the reaction chamber (8) both ends, wherein described
Lower layer's light transmission piece (5) forms first cavity (3) with the shell (1) one end inner wall；Lower layer's light transmission piece (5) with it is described
Shell (1) other end inner wall forms the reaction chamber (8)；Second cavity (10) is in the reaction chamber (8) and positions
In on the shell (1), the upper layer light transmission piece (6) is set in the second cavity (10) cavity wall.
3. pepsin according to claim 2 detects capsule, it is characterised in that：Via (2) quantity is at least one
It is a, be located at the intersection inner wall of the reaction chamber (8), shell (1), and the biological semi-permeable film (9) is set on the intersection inner wall.
4. pepsin according to claim 2 detects capsule, it is characterised in that：The shell (1) is sealing two ends
Cylinder-like structure, second cavity (10) are in the cylinder-like structure of sealing two ends, and second cavity (10) and the shell
(1) one end is connected, wherein second cavity (10) is arranged with the shell (1) with central shaft.
5. pepsin according to claim 1 detects capsule, it is characterised in that：The detection transmitter (4) includes inspection
Unit and signal transmitter unit are surveyed, the detection unit detects absorbance, and output end connects the signal transmission unit input
End, the signal transmission unit connect the signal receiving unit.
6. pepsin according to claim 1 detects capsule, it is characterised in that：The upper layer light transmission piece (6), lower layer are saturating
Mating plate (5) is quartz plate.
7. a kind of pepsin detecting system detecting capsule based on claim 1-6 any one of them pepsins, special
Sign is, including claim 1-6 any one of them pepsins detection capsule, signal receiving unit and intelligent terminal, institute
Pepsin detection capsule to be stated to communicate to connect with the signal receiving unit, the signal receiving unit is connect with intelligent terminal,
The pepsin content that pepsin detection capsule is detected by signal receiving unit be sent to the intelligent terminal into
Row record, display.
8. a kind of pepsin detection method based on the pepsin detecting system described in claim 7, which is characterized in that packet
Include following steps：
The pepsin is placed in gastric juice by S1, if using communication, is sent the capsule by feeder
Enter stomach to be fixed, if using wired communication mode, the capsule is directly swallowed into stomach, then it is fixed；
S2, the pepsin detection capsule detects pepsin content, and timing is detected by the pepsin in capsule
It detects transmitter (4) and sends detection data to the signal receiving unit, detection data is sent to by the signal receiving unit
The intelligent terminal is recorded, is shown；
Capsule after detection, if it is communication, is directly excluded body by S3 according to human stomach's metabolism
Outside；If it is wired communication mode, directly capsule is taken out by transmission line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810217426.0A CN108709857A (en) | 2018-03-16 | 2018-03-16 | Pepsin detects capsule, detecting system and detection method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810217426.0A CN108709857A (en) | 2018-03-16 | 2018-03-16 | Pepsin detects capsule, detecting system and detection method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108709857A true CN108709857A (en) | 2018-10-26 |
Family
ID=63866195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810217426.0A Pending CN108709857A (en) | 2018-03-16 | 2018-03-16 | Pepsin detects capsule, detecting system and detection method |
Country Status (1)
| Country | Link |
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| CN (1) | CN108709857A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210113765A1 (en) * | 2019-10-17 | 2021-04-22 | National Guard Health Affairs | Smart device and system for treatment of gastric reflux |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050154277A1 (en) * | 2002-12-31 | 2005-07-14 | Jing Tang | Apparatus and methods of using built-in micro-spectroscopy micro-biosensors and specimen collection system for a wireless capsule in a biological body in vivo |
| CN101854849A (en) * | 2007-11-08 | 2010-10-06 | 奥林巴斯医疗株式会社 | Blood content detecting capsule |
| CN104271028A (en) * | 2011-12-15 | 2015-01-07 | 基文影像公司 | Device, system and method for in-vivo detection of bleeding in the gastrointestinal tract |
| US20150011874A1 (en) * | 2012-02-17 | 2015-01-08 | Micropharma Limited | Ingestible medical device |
| CN105342543A (en) * | 2015-09-25 | 2016-02-24 | 重庆金山科技（集团）有限公司 | Multi-parameter wireless esophagus detection capsule and detection control system |
| CN106137099A (en) * | 2016-09-27 | 2016-11-23 | 重庆大学 | Intelligent capsule detecting system based on cloud service |
| CN208476756U (en) * | 2018-03-16 | 2019-02-05 | 重庆金山医疗器械有限公司 | Pepsin detects capsule and detection system |
-
2018
- 2018-03-16 CN CN201810217426.0A patent/CN108709857A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050154277A1 (en) * | 2002-12-31 | 2005-07-14 | Jing Tang | Apparatus and methods of using built-in micro-spectroscopy micro-biosensors and specimen collection system for a wireless capsule in a biological body in vivo |
| CN101854849A (en) * | 2007-11-08 | 2010-10-06 | 奥林巴斯医疗株式会社 | Blood content detecting capsule |
| CN104271028A (en) * | 2011-12-15 | 2015-01-07 | 基文影像公司 | Device, system and method for in-vivo detection of bleeding in the gastrointestinal tract |
| US20150011874A1 (en) * | 2012-02-17 | 2015-01-08 | Micropharma Limited | Ingestible medical device |
| CN105342543A (en) * | 2015-09-25 | 2016-02-24 | 重庆金山科技（集团）有限公司 | Multi-parameter wireless esophagus detection capsule and detection control system |
| CN106137099A (en) * | 2016-09-27 | 2016-11-23 | 重庆大学 | Intelligent capsule detecting system based on cloud service |
| CN208476756U (en) * | 2018-03-16 | 2019-02-05 | 重庆金山医疗器械有限公司 | Pepsin detects capsule and detection system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210113765A1 (en) * | 2019-10-17 | 2021-04-22 | National Guard Health Affairs | Smart device and system for treatment of gastric reflux |
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