CN108709369A - A kind of ultrasonic atomization freeze drying plant - Google Patents
A kind of ultrasonic atomization freeze drying plant Download PDFInfo
- Publication number
- CN108709369A CN108709369A CN201810357385.5A CN201810357385A CN108709369A CN 108709369 A CN108709369 A CN 108709369A CN 201810357385 A CN201810357385 A CN 201810357385A CN 108709369 A CN108709369 A CN 108709369A
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- China
- Prior art keywords
- ultrasonic atomization
- ultrasonic
- freeze drying
- nozzle
- drying plant
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
- F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B23/00—Heating arrangements
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
- F26B25/04—Agitating, stirring, or scraping devices
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/02—Drying solid materials or objects by processes not involving the application of heat by using ultrasonic vibrations
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Sustainable Development (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Drying Of Solid Materials (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Freezing, Cooling And Drying Of Foods (AREA)
Abstract
Include the ultrasonic atomization nozzle 4 being fed by liquid material transmitting device 1 the invention discloses a kind of ultrasonic atomization freeze drying plant；There are one heating mantles for the syringe exterior set of liquid material transmitting device 1；The ultrasonic atomization nozzle 4 is supported in 5 top of attemperator by a fixed support device, and is directed at the cold medium that the attemperator 5 includes；The ultrasonic atomization nozzle 4 is connected to ultrasonic wave controller 7 by high-frequency signal line 8；In addition, the ultrasonic atomization nozzle 4 is equipped with cooling-part 9, the cooling-part 9 is connected to cooler 10.Present invention obtains the powder product compared with small particle size distribution, the powder reuniting degree of production is small, and obtained solid powder is freezed due to being directly entered cold medium after spraying, and flavor keeps preferable.Present device installing and dismounting is simple, easy to use, easily controllable, easily monitors in real time, and spray rate is fast, and flavor keeps good.
Description
Technical field
The present invention relates to ultrasonic equipments, more specifically to a kind of ultrasonic atomization freeze drying plant.
Background technology
Ultrasonic wave is the sound wave that frequency is higher than 20kHz or more, is a kind of process that disseminates of mechanical oscillation in medium, passes
During broadcasting, the interaction of ultrasonic wave and medium can make the phase and amplitude etc. of ultrasonic wave change.Ultrasonic wave has
A variety of physics and sonochemical effect, are widely used.Since ultrasonic wave is there are many special physical property, and no chemical residues, peace
It is Quan Xinggao, simple and effective, therefore ultrasonic technology is widely answered in terms of chemistry, chemical industry, medicine, medical treatment and pesticide
With.In recent years, in the food industry application is also of increasing concern.Ultrasonic extraction, ultrasound sterilizing, ultrasound in food industry
Drying, ultrasound filtration, ultrasonic cleaning etc. progress are rapid, ultrasonic technology the synthesis of food additives, microbial metabolism,
Wine fermentation, food inspection, control crystallization etc. also obtain more recent application.
Such as：201710301140.6 disclose a kind of ultrasonic humidifier, the equipment include pedestal, connect base water
Case, lid close the lid on water tank, the blowing device in water tank；The bottom surface of water tank has lower concave part, the bottom of the lower concave part
Portion is equipped with energy converter；Position-limiting drum above energy converter, the energy accumulating device being set in position-limiting drum, energy accumulating device floating
On the water surface of water tank and axial centre has cumulative axis hole, the central axis of the cumulative axis hole and the central axis one of energy converter
It causes.The inventive structure is simple, and cost of implementation is relatively low, reliable operation and humidification capability is strong.
Currently, main method prepared by solid powder is to utilize spray drying technology, minority is using freeze-drying, by spraying
Solid powder prepared by dry technology causes the thermal degradation of heat-sensitive materials on the one hand due to the high-temperature operation of spray drying；It is another
Aspect can suffer from the notable loss of volatile materials.Freeze Drying Technique allows raw material to be freezed at low temperature, directly solves
The loss of thermally labile component, and porous structure particle is easily prepared by freeze-drying, make dry particle with higher product
Matter, but due to Freeze Drying Technique long processing period, energy consumption is big, technological requirement is high, production cost is high, equipment manufacturing cost is high etc.
Disadvantage limits the use of the technology.It reduces particle size and rate of drying can be improved in enhancing surface carry-over factor.
Therefore, liquid material is atomized using ultrasonic wave, the droplet of generation is accurate, it is easier to control, particle size is small, can
To obtain the particle of cellular structure, large specific surface area, the dissolubility and stability of particle are increased；The powder reuniting journey of production
It spends small.Reduce energy consumption simultaneously.
Invention content
For the above situation, the present invention provides a kind of device using ultrasonic atomization-cooling drying, it is intended to obtain smaller
The powder product of particle diameter distribution, to reach the small powder purpose of production reunion degree.
In order to achieve the above object, the present invention provides a kind of ultrasonic atomization freeze drying plants, including are passed by liquid material
The ultrasonic atomization nozzle of defeated device feed；The liquid material transmitting device includes that syringe pump, the injection pump output terminal are arranged
Syringe, and liquid pipe that the syringe is connected with the ultrasonic atomization nozzle；There are one the syringe exterior sets
Heating mantle, the heating mantle are connected to the heating device that setting temperature control device keeps temperature constant state；The ultrasonic atomization nozzle
Attemperator top is supported in by a fixed support device, and is directed at the cold medium that the attemperator includes；The heat preservation
Device is placed in above an agitating device；The ultrasonic atomization nozzle is connected to ultrasonic wave controller by high-frequency signal line；
In addition, the ultrasonic atomization nozzle is equipped with cooling-part, the cooling-part is connected to cooler.
Under preferred embodiment, the ultrasonic atomization nozzle is controlled by the ultrasonic wave controller, generates five frequencies：
20KHz、30KHz、40KHz、50KHz、60KHz。
Under preferred embodiment, the mixing plant is magnetic stirring apparatus 6.
Further include a control system under preferred embodiment, for liquid material transmitting device, heating device, ultrasonic atomization
Nozzle, fixed support device, agitating device, attemperator, ultrasonic wave controller, freeze drier manually control.
Under preferred embodiment, the syringe pump uses liquid crystal display parameter and working condition, by digital film key and rotation
Turn code switch and match the selection and setting for completing parameter, is carried out according to the soluble solid content of liquid material and spraying state
Transmission rate converts.
Under preferred embodiment, the cold medium of the attemperator is liquid nitrogen.
The present invention includes liquid material transmitting device, heating device, ultrasonic atomization ejecting device, fixed support device, stirring
Device, attemperator, ultrasonic wave controller, freeze drying plant, intelligent conveyer system, control system.The liquid material conveying dress
It sets and is made of syringe pump and syringe, syringe pump uses liquid crystal display parameter and various working conditions, by digital film key
The selection and setting for completing parameter are matched with rotary coding switch.Heating device is by high-precision digital-display temperature control device and integration
Heating mantle forms, and wherein heating mantle is fixed on the injector, and jacket temperature is controlled by digital display temperature-control device.Ultrasonic wave controls
Utensil has automatically scanning nozzle resonant frequency, automatically saves the functions such as working time.Ultrasonic wave controller passes through high-frequency signal line
By Frequency Transfer to ultrasonic spray nozzle, ultrasonic spray nozzle is spray pyrolysis type, is atomized the liquid into using high-frequency ultrasonic oscillation, mist
It is high to change granulation uniformity, and ultrasonic spray nozzle is equipped with coolant interface, can connect cooler and ultrasonic spray nozzle cools down, can have
Conducive to extension device lifetime.The droplet of atomization is continuously sprayed by the rapid fixed line of cold medium under the drive of agitating device
Mist.Ultrasonic atomization nozzle of the present invention is intelligent Multi-frequency and quick detachable nozzle.Ultrasonic spray nozzle can generate five frequencies：
20KHz,30KHz,40KHz,50KHz,60KHz；Ultrasonic spray nozzle is spray pyrolysis type, has atomization fine homogeneous and high temperature
Lower steady performance is atomized the liquid into using high-frequency ultrasonic oscillation, and the atomizing particle uniformity is high.Heating device is by high-precision
It spends digital display temperature-control device and integrated heating mantle forms, wherein heating mantle is fixed on the injector, is controlled by digital display temperature-control device
Jacket temperature processed, it is ensured that institute's spraying liquid materials belong to uniform state.
Apparatus of the present invention are sprayed first with ultrasonic wave, and it is cold that the droplet being atomized quickly enters cold medium progress
But, it and is further dried.Present invention obtains the powder product compared with small particle size distribution, the powder reuniting degree of production is small, and institute
It obtains solid powder to be freezed due to being directly entered cold medium after spraying, flavor keeps preferable.Present device installing and dismounting
Simply, easy to use, it is easily controllable, it easily monitors in real time, spray rate is fast, and flavor keeps good.
Description of the drawings
Fig. 1 is the structural schematic diagram of ultrasonic atomization freeze drying plant of the present invention.
In figure, 1. liquid material transmitting devices, 2. heating devices, 3. liquid pipes, 4. ultrasonic atomization nozzles, 5. attemperators, 6.
Magnetic stirring apparatus, 7. ultrasonic wave controllers, 8. high-frequency signal lines, 9. cooling-parts, 10. coolers.
Specific implementation mode
In order to solve the above-mentioned problems in the prior art, the present inventor conscientiously has studied existing by further investigation
Ultrasonic technology is used successfully to spraying liquid material and prepares solid powder by dry technology advantage and disadvantage in conjunction with the characteristics of ultrasonic atomization.
On this basis, the present invention provides kind to carry out the design method that spraying prepares solid powder device using ultrasonic wave.
By following specific examples, the present invention is further described, but embodiment is merely to illustrate, and can not limit this
The range of invention.
As shown in Figure 1, ultrasonic atomization freeze drying plant of the present invention, for obtaining the powder production compared with small particle size distribution
The powder reuniting degree of product, production is small and flavor keeps preferable；Device includes liquid material transmitting device 1, heating device 2, ultrasonic wave
Spraying nozzle 4, fixed support device, agitating device, attemperator 5, ultrasonic wave controller 7, freeze drying plant, intelligence transmission
System, control system.Ultrasonic atomization nozzle 4 is equipped with coolant interface simultaneously, can connect cooler 10 by ultrasonic atomization nozzle 4
Cool down, device lifetime can be conducive to extend.Specific to split, apparatus of the present invention include power supply, syringe pump, syringe, heating
Set, liquid pipe, ultrasonic spray nozzle, high-frequency signal line, ultrasonic wave controller, attemperator, magnetic stirring apparatus, ultrasonic spray nozzle are fixed
Support device, cooler.
Wherein, liquid material transmitting device 1：Liquid material is conveyed by liquid pipe；Heating device 2 includes：Ensure institute's spraying liquid materials
Belong to uniform temperature constant state；Ultrasonic atomization nozzle 4：Ultrasonic spray nozzle is multifrequency nozzle；Fixed support device is for fixed branch
Ultrasonic spray nozzle 4 is supportted, makes ultrasonic spray nozzle 4 firm in 5 overlying contact of attemperator；Mixing plant is magnetic stirring apparatus 6；Heat preservation
Contain cooling medium inside equipment；High-frequency signal line 8 is for connecting ultrasonic wave controller 7 and ultrasonic atomization nozzle 4, ultrasonic wave
Ultrasonic frequency is passed to ultrasonic spray nozzle 4 by controller 7 by high-frequency signal line 8, while ultrasonic spray nozzle 4 is equipped with cooling end
Part 9 can connect cooler 10 and ultrasonic spray nozzle 4 cools down, can be conducive to extend device lifetime.
Preferably, the method can specifically include the following contents：
(1) syringe pump of liquid material transmitting device 1 uses liquid crystal display parameter and various working conditions, is pressed by digital film
Key matched with rotary coding switch complete parameter selection and setting, can self-regulated flow velocity, can be automatically according to the solubility of liquid material
Solid content and spraying state are transmitted speed conversion.Liquid pipe 3 connects syringe and ultrasonic atomization nozzle 4, is noting
Penetrating pump drives the lower liquid pipe 3 that passes through to convey liquid material.
(2) heating device 2 is made of high-precision digital-display temperature control device and integrated heating mantle, and wherein heating mantle is fixed on note
In emitter, jacket temperature is controlled by digital display temperature-control device, it is ensured that institute's spraying liquid materials belong to uniform state.
(3) 4 device of ultrasonic atomization nozzle is intelligent Multi-frequency and quick detachable nozzle.Ultrasonic atomization nozzle 4 can generate
Five frequencies：30KHz,40KHz,50KHz,60KHz；Ultrasonic atomization nozzle 4 is spray pyrolysis type, has atomization fine homogeneous
And the advantages that stable performance under high temperature, it is atomized the liquid into using high-frequency ultrasonic oscillation, the atomizing particle uniformity is high.
(4) fixed support device upper end is for fixed support ultrasonic atomization nozzle 4, allows ultrasonic atomization nozzle and heat preservation
The contact of device 5 is firm, and fixed support device has depth-adjustment feature, can be become according to ultrasonic atomization nozzle model size
It changes；Lower end, which is used to support, is atomized drop splendid attire device, and has accurate weight identification module, can carry out quality adjustment, work as matter
When amount is beyond setting value, lower end fixed support device valve starts, container since its own gravity is landed in intelligent conveyer system,
In the case where the low temperature of intelligent conveyer system drives, is steadily entered in freeze drier by transmission object and be freeze-dried.
(5) mixing plant is magnetic stirring apparatus 6, and adjustable mixing speed can manually be adjusted according to required mixing speed
Section.
(6) attemperator 5 includes cold medium, and the droplet being atomized quickly enters cold medium and cooled down, and gained is solid
Body powder is freezed due to being directly entered cold medium after spraying, and flavor keeps preferable.Frozen droplet is further
It is dry, obtain powder.
(7) ultrasonic wave controller 7 has the function of automatically scanning nozzle resonant frequency, automatically saves the working time etc..High frequency
Signal wire 8 is used to connect ultrasonic wave controller 7 and ultrasonic atomization nozzle 4, and ultrasonic wave controller 7 will by high-frequency signal line 8
High frequency electrical signal passes to ultrasonic spray nozzle.
(8) ultrasonic spray nozzle 4 is equipped with coolant interface or cooling-part 9, can connect cooler 10 and carry out ultrasonic spray nozzle
Cooling, cooler 10 are compressed air, take over filter solution pressure valve, control pressure 0.02MPa, and cooler is released by ultrasonic spray nozzle
It puts.
(9) it is connect by freeze drier by intelligent conveyer system with ultrasonic spray system, is being with intelligence transmission
Under the connection of system, it will be freeze-dried in transmission object smooth transfer to freeze drier.
(10) control system can manually control single unit system, including to liquid material transmitting device, heating device, ultrasound
Wave spraying nozzle device, fixed support device, agitating device, attemperator, ultrasonic wave controller, freeze drying plant, intelligence
Conveyer system carries out manual setting.
Embodiment 1：
The present invention seasons the application of soup powder preparing natural seafood.Soup is thawed, the pretreatments such as homogeneous, heating
It is 50 DEG C to cover heating temperature, ensures that liquid material to be sprayed is sprayed under 50 DEG C of temperature conditions, it is ensured that institute's spraying liquid materials belong to uniform
State.Feed rate is 5.0mL/min, ultrasonic power 3W, supersonic frequency 40KHz, rapid by the droplet of ullrasonic spraying
Into in coolant liquid, under agitating device drive, it is carried out continuously spraying.Gained powder microstructure is smooth, and seamless, rupture is now
As.In drop, the layer rich in protein has size can since the acquisition of this atomizing freeze drying is spherical particles shape product
The advantages that control, porous, instant, good fluidity, good stability.Ultrasonic atomization-freeze drying process helps to prepare specific surface
The powder that product is big, voidage is high, structure is uniform and stable.The thickness and elasticity of protein, increasing surface flexibility may make to do
The contraction of dry period particle does not rupture, and therefore, particle shows more wrinkles and roughness.Grain shape is more smooth, compares table
Area is smaller, and particle properties are more stable；Powder yield is high；Powder water content is 4.8%；Bulk density is 0.102g/mL；Dissolving
Property is good；Powder volatile flavor substance prepared by ultrasonic atomization-freeze drying process is kept, rich in preferable flavour.
Comparative example 1：
Soup is thawed, the pretreatments such as homogeneous, carries out freeze-drying and prepare powder.Gained powder microstructure particle
Diameter is big, particle size distribution range is wide, irregular.Powder water content 7.3%, bulk density 0.079g/mL；Dissolubility is poor；
Powder volatile flavor, the taste substance of freeze drying process preparation keep good.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Any one skilled in the art in the technical scope of present disclosure, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (7)
1. a kind of ultrasonic atomization freeze drying plant, which is characterized in that include the ultrasonic wave being fed by liquid material transmitting device (1)
Spraying nozzle (4)；The liquid material transmitting device (1) includes syringe pump, the syringe for injecting pump output terminal setting, and is incited somebody to action
The liquid pipe of the syringe and the ultrasonic atomization nozzle (4) connection；
There are one heating mantle, the heating mantle is connected to setting temperature control device and is kept for adding for temperature constant state the syringe exterior set
Thermal (2)；
The ultrasonic atomization nozzle (4) is supported in attemperator (5) top, the attemperator by a fixed support device
(5) added with cold medium；The attemperator (5) is placed in above an agitating device；
The ultrasonic atomization nozzle (4) is connected to ultrasonic wave controller (7) by high-frequency signal line (8)；In addition, the ultrasound
Wave spraying nozzle (4) is equipped with cooling-part (9), and the cooling-part (9) is connected to cooler (10).
2. ultrasonic atomization freeze drying plant according to claim 1, which is characterized in that the ultrasonic atomization nozzle (4
It is controlled by the ultrasonic wave controller (7), generates five frequencies：20KHz,30KHz,40KHz,50KHz,60KHz.
3. ultrasonic atomization freeze drying plant according to claim 1, which is characterized in that the mixing plant stirs for magnetic force
Mix device (6).
4. ultrasonic atomization freeze drying plant according to claim 1, which is characterized in that further include one in outer closures
The monoblock type freeze drier of other component.
5. ultrasonic atomization freeze drying plant according to claim 4, which is characterized in that further include a control system,
For to liquid material transmitting device (1), heating device (2), ultrasonic atomization nozzle (4), fixed support device, agitating device, guarantor
Warm device (5), ultrasonic wave controller (7), freeze drier manually control.
6. ultrasonic atomization freeze drying plant according to claim 1, which is characterized in that the syringe pump uses liquid crystal
Show parameter and working condition, matches the selection and setting for completing parameter, root with rotary coding switch by digital film key
It is transmitted speed conversion according to the soluble solid content and spraying state of liquid material.
7. ultrasonic atomization freeze drying plant according to claim 1, which is characterized in that the institute of the attemperator (5)
It is liquid nitrogen to state cold medium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810357385.5A CN108709369A (en) | 2018-04-20 | 2018-04-20 | A kind of ultrasonic atomization freeze drying plant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810357385.5A CN108709369A (en) | 2018-04-20 | 2018-04-20 | A kind of ultrasonic atomization freeze drying plant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108709369A true CN108709369A (en) | 2018-10-26 |
Family
ID=63867332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810357385.5A Pending CN108709369A (en) | 2018-04-20 | 2018-04-20 | A kind of ultrasonic atomization freeze drying plant |
Country Status (1)
| Country | Link |
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| CN (1) | CN108709369A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111250283A (en) * | 2020-03-13 | 2020-06-09 | 北京控制工程研究所 | Atomizing nozzle with auxiliary heating device suitable for rapid freezing environment |
| CN113606880A (en) * | 2021-08-12 | 2021-11-05 | 四川和诚振药科技有限公司 | Method for realizing dynamic ultra-fast agglomeration-free freeze drying by utilizing high-acceleration vibration |
| ES2912038A1 (en) * | 2022-01-14 | 2022-05-24 | Asociacion De Investig De Las Industrias Ceramicas Aice | Microatomization equipment for the characterization of raw material samples and characterization procedure of a microatomized sample (Machine-translation by Google Translate, not legally binding) |
| CN115289788A (en) * | 2022-08-05 | 2022-11-04 | 江中药业股份有限公司 | Vacuum spray freeze dryer |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE46022L (en) * | 1976-12-30 | 1978-06-30 | Boehringer Mannheim Gmbh | Production of frozen granulates |
| EP1590613A2 (en) * | 2003-02-07 | 2005-11-02 | Ferro Corporation | Lyophilization method and apparatus for producing particles |
| CN101441030A (en) * | 2008-12-16 | 2009-05-27 | 澳门理工学院 | Integrated atomizing freeze drying equipment and method |
| CN202342918U (en) * | 2011-12-19 | 2012-07-25 | 江西师范大学 | Ultrasonic atomization concentration device |
| US20150226478A1 (en) * | 2010-08-04 | 2015-08-13 | Ima Life North America Inc. | Bulk freeze drying using spray freezing and agitated drying |
| CN105188740A (en) * | 2013-03-07 | 2015-12-23 | 普罗菲布里克有限公司 | Powder formulation comprising thrombin and fibrinogen |
| CN105582683A (en) * | 2014-10-21 | 2016-05-18 | 中国科学院上海药物研究所 | Dynamically-monitored high-frequency ultrasound atomized particle preparation system |
-
2018
- 2018-04-20 CN CN201810357385.5A patent/CN108709369A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE46022L (en) * | 1976-12-30 | 1978-06-30 | Boehringer Mannheim Gmbh | Production of frozen granulates |
| EP1590613A2 (en) * | 2003-02-07 | 2005-11-02 | Ferro Corporation | Lyophilization method and apparatus for producing particles |
| CN101441030A (en) * | 2008-12-16 | 2009-05-27 | 澳门理工学院 | Integrated atomizing freeze drying equipment and method |
| US20150226478A1 (en) * | 2010-08-04 | 2015-08-13 | Ima Life North America Inc. | Bulk freeze drying using spray freezing and agitated drying |
| CN202342918U (en) * | 2011-12-19 | 2012-07-25 | 江西师范大学 | Ultrasonic atomization concentration device |
| CN105188740A (en) * | 2013-03-07 | 2015-12-23 | 普罗菲布里克有限公司 | Powder formulation comprising thrombin and fibrinogen |
| CN105582683A (en) * | 2014-10-21 | 2016-05-18 | 中国科学院上海药物研究所 | Dynamically-monitored high-frequency ultrasound atomized particle preparation system |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111250283A (en) * | 2020-03-13 | 2020-06-09 | 北京控制工程研究所 | Atomizing nozzle with auxiliary heating device suitable for rapid freezing environment |
| CN111250283B (en) * | 2020-03-13 | 2021-06-11 | 北京控制工程研究所 | Atomizing nozzle with auxiliary heating device suitable for rapid freezing environment |
| CN113606880A (en) * | 2021-08-12 | 2021-11-05 | 四川和诚振药科技有限公司 | Method for realizing dynamic ultra-fast agglomeration-free freeze drying by utilizing high-acceleration vibration |
| ES2912038A1 (en) * | 2022-01-14 | 2022-05-24 | Asociacion De Investig De Las Industrias Ceramicas Aice | Microatomization equipment for the characterization of raw material samples and characterization procedure of a microatomized sample (Machine-translation by Google Translate, not legally binding) |
| CN115289788A (en) * | 2022-08-05 | 2022-11-04 | 江中药业股份有限公司 | Vacuum spray freeze dryer |
| CN115289788B (en) * | 2022-08-05 | 2024-04-05 | 江中药业股份有限公司 | Vacuum spray freeze dryer |
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Application publication date: 20181026 |
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