CN108684963A - Small-peptide chelated manganese of a kind of nanometer for feed addictive and preparation method thereof - Google Patents
Small-peptide chelated manganese of a kind of nanometer for feed addictive and preparation method thereof Download PDFInfo
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- CN108684963A CN108684963A CN201810488555.3A CN201810488555A CN108684963A CN 108684963 A CN108684963 A CN 108684963A CN 201810488555 A CN201810488555 A CN 201810488555A CN 108684963 A CN108684963 A CN 108684963A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/14—Pretreatment of feeding-stuffs with enzymes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Abstract
The present invention relates to chemosynthesis technical fields, and in particular to small-peptide chelated manganese of a kind of nanometer for feed addictive and preparation method thereof.It is unfavorable for the problem of pig is to the absorption of manganese element and pollution environment for inorganic manganese is added directly in feed, the technical scheme is that, include the following steps:[1]Bean cake powder dissolves:Bean cake powder is dissolved in the buffer solution of pH=2.2-8.0, bean cake powder solution is obtained;[2]It is prepared by dry Gly-His-Lys:By Bu Zhou [1]Obtained bean cake powder solution heat treatment, is then added alkali protease and flavor protease, heating enzymolysis, and then boiling water bath enzyme deactivation activity, centrifugal filtration obtains enzymolysis liquid, is dried to obtain dry Gly-His-Lys;[3]The preparation of the small-peptide chelated manganese of nanometer:By Bu Zhou [2]Obtained dry Gly-His-Lys dissolve to obtain small peptide solution, under condition of heating and stirring, inorganic manganese solution are added, small peptide is made to react to form chelate with manganese, separation, it is dry after up to the small-peptide chelated manganese of nanometer.The present invention is suitable for pannage.
Description
Technical field
The present invention relates to chemosynthesis technical fields, and in particular to a kind of small-peptide chelated manganese of nanometer for feed addictive
And preparation method thereof.
Background technology
Manganese mainly influences sugar, lipid and protein metabolism in the form of enzyme, to restrict the skeleton development of pig, breeding, life
Long and immunity function.
Manganese is the enzymes such as arginase in body, prolinase, connecing of pyruvic acid enzyme, polymerase, superoxide dismutase
Constituent.In recent years the study found that the aging of mammal may reduce caused antioxidation decrease with manganese have
It closes, manganese is required for activity as metal prothetic group.Mainly as the composition portion of connecing of pyruvic acid enzyme, mitochondria and arginase
Divide and activation of certain enzymes plays a role.Dietary Mn influences to be by it to containing manganese key enzyme base on active in body
It is realized because of the adjusting of expression, and the gene expression on transcriptional level is the first step of enzyme whole gene expression.To bone
Bone organic substrate forms also extremely important.In general, breeding is higher than growth to the needs of manganese.
In the prior art, the mode that manganese is added in feed is generally the inorganic salts for directly adding manganese.Inorganic salts are not only unfavorable
The absorption of manganese element in pig is to feed causes the reproductive performance of pig to decline, and can largely be drained to be easy to pollute by pig
Environment.
Invention content
It is unfavorable for the problem of pig is to the absorption of manganese element and pollution environment for the above-mentioned inorganic manganese that added directly in feed,
The present invention provides a kind of small-peptide chelated manganese of the nanometer for feed addictive and preparation method thereof, its object is to:By that will receive
The small-peptide chelated manganese of rice enhances the nutrient functional of manganese element in feed, improves the biological value of manganese as feed addictive, and
Reduce environmental pollution.
The technical solution adopted by the present invention is as follows:
A kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive, includes the following steps:
[1]Bean cake powder dissolves:Bean cake powder is dissolved in the buffer solution of pH=2.2-8.0, bean cake powder solution is obtained;
[2]It is prepared by dry Gly-His-Lys:By Bu Zhou [1]Obtained bean cake powder solution heat treatment, is then added alkali protease and wind
Taste protease, heating enzymolysis, then boiling water bath enzyme deactivation activity, centrifugal filtration obtain enzymolysis liquid, are dried to obtain dry Gly-His-Lys;
[3]The preparation of the small-peptide chelated manganese of nanometer:By Bu Zhou [2]Obtained dry Gly-His-Lys dissolve to obtain small peptide solution, and heating is stirred
Under the conditions of mixing, inorganic manganese solution is added, small peptide is made to react to form chelate with manganese, it is small-peptide chelated up to nanometer after separation, drying
Manganese.
After the technical program, make manganese element with it is small-peptide chelated so that manganese element be easier absorbed by organism, to
On the one hand the nutrient functional and biological value for improving manganese element, on the other hand reduce micro- in excreta contain
Amount, to reduce environmental pollution.Further, since the absorption rate higher of manganese element, and the raw soybean dregs powder used has
Cheap advantage, thus advantageously reduce cost.The small-peptide chelated manganese purity height of nanometer, the crystalline structure prepared by this method
It is good, to be conducive to accurately control usage amount.
Preferably, buffer solution is formulated by 0.2M disodium phosphate solns and 0.1M citric acid solutions.
Preferably, a concentration of 155-165g/L of bean cake powder solution.
Preferably, Bu Zhou [2]The mass ratio of neutral and alkali protease and flavor protease is 1:1.
Preferably, Bu Zhou [2]The gross mass of neutral and alkali protease and flavor protease is the 10-11% of bean cake powder quality.
Preferably, Bu Zhou [2]Detailed process be at 35-45 DEG C stir 10-15min;It is heat-treated at 89-92 DEG C again
15-20min;Alkali protease and flavor protease is added, is digested 4-6 hours in 50-60 DEG C, pH=6.5-7.5, oscillation, enzyme
It lives in boiling water bath enzyme deactivation after solution, adjusts pH value to 4-5, centrifugation, filtering obtain enzymolysis liquid, dry, obtain dry Gly-His-Lys.
Preferably, inorganic manganese solution is the manganese sulfate solution that mass fraction is 15-25%.
Preferably, Bu Zhou [3]Detailed process be to pour into small peptide solution in reaction vessel, adjustment pH is 7.5-8.5, warm
Degree is 50-60 DEG C, is added with stirring manganese sulfate solution, and the mass ratio of the quality and manganese sulfate monohydrate that make dry Gly-His-Lys is 3-5 ︰ 1, is added
3-8min is reacted after complete again, detaches, be dried to obtain the small-peptide chelated manganese of nanometer.
Preferably, Bu Zhou [3]The middle reagent adjusted used in pH is 0.1M sodium hydroxide solutions.
The present invention also provides the small-peptide chelated manganese of nanometer prepared using the above method.Using small-peptide chelated manganese as feed
Additive is than directly using inorganic manganese to have better palatability as additive.
In conclusion by adopting the above-described technical solution, the beneficial effects of the invention are as follows:
1. make manganese element with it is small-peptide chelated so that manganese element be easier absorbed by organism, on the one hand improve manganese
The nutrient functional and biological value of element, improve the reproductive performance of animal, on the other hand reduce micro in excreta
The content of element, to reduce environmental pollution.
2. due to the absorption rate higher of manganese element, thus advantageously reducing cost.
3. it is good by the small-peptide chelated manganese purity height of the nanometer of this method preparation, crystalline structure, to be conducive to accurately control
Usage amount processed.
4. preferably being fitted as feed addictive than directly using inorganic manganese to have as additive using small-peptide chelated manganese
Mouth property.
5. price is relatively high for existing small-peptide chelated object (the especially small-peptide chelated salt of individual event), and the raw material that the present invention uses
Bean cake powder has the advantages that cheap.
6. digesting small peptide using dregs of beans, using Organometallic compounds reaction and crystal polymorph control, and spray-dried it is prepared for
The small-peptide chelated manganese of the high nanometer of chelating degree, and provide new research for other nanometers of small peptide microelement chelate research promotions and think
Road.
Specific implementation mode
All features disclosed in this specification or disclosed all methods or in the process the step of, in addition to mutually exclusive
Feature and/or step other than, can combine in any way.
A kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive, includes the following steps:
[1]Bean cake powder dissolves:Bean cake powder is dissolved in the buffer solution of pH=2.2-8.0, bean cake powder solution is obtained;
[2]It is prepared by dry Gly-His-Lys:By Bu Zhou [1]Obtained bean cake powder solution heat treatment, is then added alkali protease and wind
Taste protease, heating enzymolysis, then boiling water bath enzyme deactivation activity, centrifugal filtration obtain enzymolysis liquid, are dried to obtain dry Gly-His-Lys;
[3]The preparation of the small-peptide chelated manganese of nanometer:By Bu Zhou [2]Obtained dry Gly-His-Lys dissolve to obtain small peptide solution, and heating is stirred
Under the conditions of mixing, inorganic manganese solution is added, small peptide is made to react to form chelate with manganese, it is small-peptide chelated up to nanometer after separation, drying
Manganese.
After the technical program, make manganese element with it is small-peptide chelated, on the one hand so that
Preferably, buffer solution is formulated by 0.2M disodium phosphate solns and 0.1M citric acid solutions.
Preferably, a concentration of 155-165g/L of bean cake powder solution.
Preferably, Bu Zhou [2]The mass ratio of neutral and alkali protease and flavor protease is 1:1.
Preferably, Bu Zhou [2]The gross mass of neutral and alkali protease and flavor protease is the 10-11% of bean cake powder quality.
Preferably, Bu Zhou [2]Detailed process be at 35-45 DEG C stir 10-15min;It is heat-treated at 89-92 DEG C again
15-20min;Alkali protease and flavor protease is added, is digested 4-6 hours in 50-60 DEG C, pH=6.5-7.5, oscillation, enzyme
It lives in boiling water bath enzyme deactivation after solution, adjusts pH value to 4-5, centrifugation, filtering obtain enzymolysis liquid, dry, obtain dry Gly-His-Lys.
Preferably, inorganic manganese solution is the manganese sulfate solution that mass fraction is 15-25%.
Preferably, Bu Zhou [3]Detailed process be to pour into small peptide solution in reaction vessel, adjustment pH is 7.5-8.5, warm
Degree is 50-60 DEG C, is added with stirring manganese sulfate solution, and the mass ratio of the quality and manganese sulfate monohydrate that make dry Gly-His-Lys is 3-5 ︰ 1, is added
3-8min is reacted after complete again, detaches, be dried to obtain the small-peptide chelated manganese of nanometer.
Preferably, Bu Zhou [3]The middle reagent adjusted used in pH is 0.1M sodium hydroxide solutions.
The present invention also provides the small-peptide chelated manganese of nanometer prepared using the above method.
Technical scheme of the present invention is further described below by specific embodiment and test example.
Embodiment 1
A kind of preparation method of the small-peptide chelated manganese of feed addictive nanometer, includes the following steps:
(1) preparation of buffer solution:The buffer solution of pH2.2~8.0 is prepared with 0.2M disodium hydrogen phosphates and 0.1M citric acids
1000mL。
(2) prepared by dry Gly-His-Lys:It takes 155g bean cake powders (granularity≤0.6mm) to be dissolved in the buffer solution of 1000ml, adjusts pH value extremely
4.3, the acid processing 10min at 35-40 DEG C;Again 15min is heat-treated at 89-90 DEG C;Then in alkali protease and flavor egg
White enzyme mass ratio is 1:1, temperature is maintained at 50-55 DEG C, pH 7.0, and enzyme concentration (M/S) is placed in constant temperature under conditions of being 10.5%
Oscillation enzymolysis 4 hours on oscillator, then live 10min in boiling water bath enzyme deactivation, adjust pH value to 4-4.5, then in 3000r/min,
10min is centrifuged, and filters to obtain enzymolysis liquid, is spray-dried, is obtained dry Gly-His-Lys.
(3) preparation of small peptide solution:It is small peptide solution dry Gly-His-Lys to be dissolved in tap water, saturated solution is made.
(4) preparation of manganese solution:The accurate manganese sulfate monohydrate powder for weighing 25g is moved into originally water dissolution on a small quantity
In 100mL volumetric flasks, with tap water constant volume, shake up.
(5) preparation of 100kg nanometers of small-peptide chelated manganese:Small peptide solution is at the uniform velocity poured into the container with agitating device,
It is 8.50 to adjust pH, and temperature is 50-55 DEG C, mixing speed 120r/min, rate of charge (enzymolysis the ratio between small peptide and manganese sulfate monohydrate)
It is 3:1, manganese solution is first at the uniform velocity added with the speed of 100mL/min in small peptide solution, after the 1/20 of total amount is added in manganese solution,
It is at the uniform velocity added with the speed of 1000 mL/min again, to the end of reacting 3min again after material adds.
(6) wait for that reaction finishes separation and is drying to obtain the small-peptide chelated manganese of nanometer, output capacity 99.88% measures average particle size
For 219nm.
Embodiment 2
A kind of preparation method of the small-peptide chelated manganese of feed addictive nanometer, includes the following steps:
(1) preparation of buffer solution:It is 2.2~8.0 to prepare pH with 0.2M disodium phosphate solns and 0.1M citric acid solutions
Buffer solution;
(2) prepared by dry Gly-His-Lys:Bean cake powder is dissolved in the buffer solution of step (1), makes a concentration of 165g/L of bean cake powder,
40-45 DEG C of stirring 15min;Again 20min is heat-treated at 90-92 DEG C;Alkali protease and flavor protease is added, in 55-60
DEG C, pH=6.5-7.5, oscillation enzymolysis 6 hours, live in boiling water bath enzyme deactivation after enzymolysis, adjust pH value to 4.7, centrifugation, filtering,
Enzymolysis liquid is obtained, it is dry, obtain dry Gly-His-Lys;
(3) preparation of small peptide solution:It is small peptide solution dry Gly-His-Lys to be dissolved in water, saturated solution is made;
(4) preparation of manganese solution:Manganese sulfate monohydrate is dissolved in water and is configured to the manganese sulfate solution that mass fraction is 20%;
(5) preparation of the small-peptide chelated manganese solution of nanometer:Small peptide solution is poured into reaction vessel, adjustment pH is 8.0, temperature
It is 55-60 DEG C, is added with stirring manganese sulfate solution, the mass ratio of the quality and manganese sulfate monohydrate that make dry Gly-His-Lys is 5 ︰ 1, after adding
8min is reacted again;
(6) it detaches, be drying to obtain the small-peptide chelated manganese of nanometer.
Test example 1
1. Basic drawing is with reference to NRC (2012) pig nutritional need and China"Swine rearing standard"(NY/T 65-2004) matches
System, basal diet use corn-soybean meal, control group to be used as nutritional supplement using inorganic microelement (manganese sulfate monohydrate);
The small-peptide chelated manganese of nanometer prepared by test group addition embodiment 1 substitutes the manganese sulfate monohydrate of same price, Basic drawing composition and
Every nutritive index is shown in Table 1.
1 diet of table forms and trophic level (air bells dry basis)
Note:1) composite mineral salt is consisting of (every kilogram of diet):CaHPO4 22.21g,MgSO4·7H20 4.11g,
FeSO4·H2O 125mg,MnSO4·H2O 140mg/ nanometers of small-peptide chelated manganese 20 ㎎, ZnSO4·7H2O 133mg,KI
0.33mg,Na2SeO3·5H2O 10mg,K2SO4 3.92g,NaCl l1.0g.
2) nutritive index is measured value.
2. being designed using single factor experiment, select health similar in ± 3 days 100 days fat bodies of gestation, parity big through producing long *
Binary sow 30 is used as subjects, and every group of 15 repetitions are each to repeat 1 sow, and experimental period is pregnant 100 days to farrowing
14 days afterwards.Experiment sow grouping situation is shown in Table 2.
Table 2 tests sow and is grouped situation
3. testing index and method:(1) lactation amount=(the initial litter weight of litter weight -) × 4;(2) the head number of 14 days piglets is recorded
And litter weight;The result is shown in tables 3.
3 sow reproductive performance of table
Note:All data P > 0.05.
4. as shown in table 3, compared with the control group, test group piglet fortnight (14d) is average improves 8.46% (P> again;
0.05), milk yield of sow improves 4.9% (P > 0.05), illustrates to be substituted with the small-peptide chelated manganese of nanometer of lower dosage inorganic
Manganese does not influence the reproductive performance of sow not only, moreover it is possible to reduce pollution of the metallic element to environment.
The specific implementation mode of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
Cannot the limitation to the application protection domain therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, under the premise of not departing from technical scheme design, various modifications and improvements can be made, these belong to this
The protection domain of application.
Claims (10)
1. a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive, which is characterized in that include the following steps:
[1]Bean cake powder dissolves:Bean cake powder is dissolved in the buffer solution of pH=2.2-8.0, bean cake powder solution is obtained;
[2]It is prepared by dry Gly-His-Lys:By Bu Zhou [1]Obtained bean cake powder solution heat treatment, is then added alkali protease and flavor egg
White enzyme, heating enzymolysis, then boiling water bath enzyme deactivation activity, centrifugal filtration obtain enzymolysis liquid, are dried to obtain dry Gly-His-Lys;
[3]The preparation of the small-peptide chelated manganese of nanometer:By Bu Zhou [2]Obtained dry Gly-His-Lys dissolve to obtain small peptide solution, heating stirring item
Under part, inorganic manganese solution is added, small peptide is made to react to form chelate with manganese, up to the small-peptide chelated manganese of nanometer after separation, drying.
2. a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive described in accordance with the claim 1, feature
It is:The buffer solution is formulated by 0.2M disodium phosphate solns and 0.1M citric acid solutions.
3. a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive described in accordance with the claim 1, feature
It is:A concentration of 155-165g/L of the bean cake powder solution.
4. a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive described in accordance with the claim 1, feature
It is:Bu Zhou [2]The mass ratio of neutral and alkali protease and flavor protease is 1:1.
5. a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive described in accordance with the claim 1, feature
It is:Bu Zhou [2]The gross mass of neutral and alkali protease and flavor protease is the 10-11% of bean cake powder quality.
6. according to a kind of preparation side of the small-peptide chelated manganese of nanometer for feed addictive described in any one of claim 1 to 5
Method, it is characterised in that:Bu Zhou [2]Detailed process be at 35-45 DEG C stir 10-15min;Again 15- is heat-treated at 89-92 DEG C
20min;Alkali protease and flavor protease is added, is digested 4-6 hours in 50-60 DEG C, pH=6.5-7.5, oscillation, enzymolysis knot
It lives in boiling water bath enzyme deactivation after beam, adjusts pH value to 4-5, centrifugation, filtering obtain enzymolysis liquid, dry, obtain dry Gly-His-Lys.
7. a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive described in accordance with the claim 1, feature
It is:The inorganic manganese solution is the manganese sulfate solution that mass fraction is 15-25%.
8. special according to a kind of preparation method of the small-peptide chelated manganese of nanometer for feed addictive described in claim 1 or 7
Sign is:Bu Zhou [3]Detailed process be small peptide solution is poured into reaction vessel, adjustment pH be 7.5-8.5, temperature 50-
60 DEG C, it is added with stirring manganese sulfate solution, the mass ratio of the quality and manganese sulfate monohydrate that make dry Gly-His-Lys is 3-5 ︰ 1, after adding again
3-8min is reacted, detaches, be dried to obtain the small-peptide chelated manganese of nanometer.
9. the preparation method of the small-peptide chelated manganese of a kind of nanometer for feed addictive according to claim 8, feature
It is:Bu Zhou [3]The middle reagent adjusted used in pH is 0.1M sodium hydroxide solutions.
10. prepared by a kind of preparation method of the small-peptide chelated manganese of the nanometer described in accordance with the claim 1 for feed addictive
The small-peptide chelated manganese of nanometer.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115595276A (en) * | 2022-10-26 | 2023-01-13 | 湖北贯美科技有限公司（Cn） | Moisturizing and whitening cosmetic and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102827907A (en) * | 2012-08-02 | 2012-12-19 | 广州市博善生物饲料有限公司 | Preparation method and application of small peptide chelated manganese compound |
| CN106035983A (en) * | 2016-06-24 | 2016-10-26 | 河南广安生物科技股份有限公司 | Preparation method of feed additive nano small peptide chelated copper |
| CN106721060A (en) * | 2016-12-19 | 2017-05-31 | 陈石良 | A kind of preparation method of soybean small peptide nanometer selenium chelate |
| CN106721283A (en) * | 2016-12-09 | 2017-05-31 | 广州傲农生物科技有限公司 | Small-peptide chelated manganese compound of one main laver and preparation method and application |
-
2018
- 2018-05-21 CN CN201810488555.3A patent/CN108684963A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102827907A (en) * | 2012-08-02 | 2012-12-19 | 广州市博善生物饲料有限公司 | Preparation method and application of small peptide chelated manganese compound |
| CN106035983A (en) * | 2016-06-24 | 2016-10-26 | 河南广安生物科技股份有限公司 | Preparation method of feed additive nano small peptide chelated copper |
| CN106721283A (en) * | 2016-12-09 | 2017-05-31 | 广州傲农生物科技有限公司 | Small-peptide chelated manganese compound of one main laver and preparation method and application |
| CN106721060A (en) * | 2016-12-19 | 2017-05-31 | 陈石良 | A kind of preparation method of soybean small peptide nanometer selenium chelate |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115595276A (en) * | 2022-10-26 | 2023-01-13 | 湖北贯美科技有限公司（Cn） | Moisturizing and whitening cosmetic and preparation method thereof |
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Application publication date: 20181023 |
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| RJ01 | Rejection of invention patent application after publication |