CN108671117A - A kind of tablet for chronic nephritis - Google Patents
A kind of tablet for chronic nephritis Download PDFInfo
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- CN108671117A CN108671117A CN201810829716.0A CN201810829716A CN108671117A CN 108671117 A CN108671117 A CN 108671117A CN 201810829716 A CN201810829716 A CN 201810829716A CN 108671117 A CN108671117 A CN 108671117A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The present invention provides a kind of tablet for chronic nephritis, is related to Chinese medicine technical field.The present invention is made of following raw material:Radix Astragali, RADIX ACONITI LATERALIS PREPARATA, motherwort, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam.Tablet for chronic nephritis prescription proportioning of the present invention is reasonable, makes simply, easy to use;With warm kidney, QI invigorating.For the soreness of waist caused by kidney qi loss, tired, chilly and enuresis nocturna increase function, treat chronic renal insufficiency good effect, quick, without any side effects.
Description
Technical field
The present invention relates to Chinese medicine technical fields, and in particular to a kind of tablet for chronic nephritis.
Background technology
It is on the rise with the development and environmental pollution of industrial society, nephropathy is in rising trend in the whole world.According to
The World Health Organization(WHO)Data, there are 2.5 hundred million people's development of kidney disease in the current whole world, and the disease incidence rapidly rises.To 2010
Year, there is 40%~50% people's nephrotic syndrome in the whole world.
Shenkangning caters to demand of many patients to renal drug with its unique Chinese patent drug, and there is tonifying spleen warm kidney, excreting dampness to live
Blood.The effect of for weak, waist and knee crymodynia caused by the insufficiency of both the spleen and the kindey, blood stasis dampness.
The dosage form of Shenkangning on the market includes tablet for chronic nephritis, shenkangning capsules, Shenkangning particle etc., and wherein tablet is because of it
Easy to carry, stability is good, the advantages such as convenient to take, has obtained liking for patient, the present invention is reasonable by a kind of proportioning, makes
Simple formulation and technology, has obtained good effect, uses tablet for chronic nephritis convenient for production.
Invention content
In view of the shortcomings of the prior art, the present invention provides a kind of tablet for chronic nephritis.
In order to achieve the above object, technical scheme of the present invention is achieved by the following technical programs:
A kind of tablet for chronic nephritis, the tablet for chronic nephritis are made of the raw material of following parts by weight:12-22 parts of Radix Astragali, RADIX ACONITI LATERALIS PREPARATA 21-35
Part, 19-28 parts of motherwort, 10-35 parts of cynomorium songaricum, 12-22 parts of Radix Salviae Miltiorrhizae, 18-21 parts of Poria cocos, 20-30 parts of rhizoma alismatis, 15-20 parts of Chinese yam.
Further, the tablet for chronic nephritis is made of the raw material of following parts by weight:15-20 parts of Radix Astragali, RADIX ACONITI LATERALIS PREPARATA 25-32
Part, 20-26 parts of motherwort, 15-30 parts of cynomorium songaricum, 15-20 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 22-28 parts of rhizoma alismatis, 18-20 parts of Chinese yam.
Further, the tablet for chronic nephritis is made of the raw material of following parts by weight:20 parts of Radix Astragali, 30 parts of RADIX ACONITI LATERALIS PREPARATA, benefit are female
20 parts of grass, 20 parts of cynomorium songaricum, 15 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 25 parts of rhizoma alismatis, 20 parts of Chinese yam.
Further, the concocting method of the tablet for chronic nephritis, includes the following steps:
S1, Radix Astragali is cleaned up, dries and is placed in the soak of cellulase, pectase, lignoenzyme mixed
It is filtered after impregnating 1-3h, the alpine yallow herb that obtains that treated;
S2, by ethyl alcohol and pure water by volume 3:2 mixing, stir 1-2min, obtain 60% ethanol solution;
S3,60% ethanol solution for preparing step S1 treated Radix Astragalis and step S2 are according to mass ratio 3:2 are uniformly mixed, close
Standing is closed, stirring is primary per 2-2.2h, and bored profit 35-45h obtains the Radix Astragali moisturized to section;
S4, the Radix Astragali for moisturizing section extract 3 times in 60 °C, and every time plus 60% ethyl alcohol triplication, double quantity and one times are measured, 100 °C
It is evaporated, obtains thick medicinal extract;
S5, RADIX ACONITI LATERALIS PREPARATA, motherwort, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam are attached separately to be impregnated with pure water in container respectively
Piece 10-18min is respectively put into after cleaning in medicine pot, adds the pure water boiling 60min for accounting for pot 2/3,40-70 is placed on after boiling
DEG C climatic chamber drying sterilizing 2-6h, tag, motherwort after being sterilized, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam,
It carries out Ultramicro-powder crushing respectively again, is uniformly mixed, obtains Chinese medicine mixed powder;
S6, Chinese medicine mixed powder prepared by the step S4 Radix Astragali thick medicinal extracts prepared and step S5 is mixed, is stirred evenly, is made
Grain, it is dry.
S7, it directly packs, or by the dry particle and adhesive, mix lubricant in S6 steps, tabletting obtains Shenkangning
Piece.
Further, alpine yallow herb described in step S4 stir-fries 7min at 120 DEG C of temperature, then proceedes to continue to stir-fry in 95 DEG C
10min。
Further, the tablet for chronic nephritis is one kind in powder, tablet.
The effect of constituent part and effect:
The present invention provides a kind of tablet for chronic nephritis, and advantage is compared with prior art:
Tablet for chronic nephritis prescription proportioning of the present invention is reasonable, makes simply, easy to use;With warm kidney, QI invigorating.Draw for kidney qi loss
The soreness of waist, tired risen, chilly and enuresis nocturna increase function, treat chronic renal insufficiency good effect, quick, and no any poison is secondary to be made
With.
Specific implementation mode
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, with reference to the embodiment of the present invention pair
Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is a part of the invention
Embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making wound
The every other embodiment obtained under the premise of the property made labour, shall fall within the protection scope of the present invention.
Embodiment 1:
The present embodiment tablet for chronic nephritis is made of the raw material of following parts by weight:20 parts of Radix Astragali, 30 parts of RADIX ACONITI LATERALIS PREPARATA, 20 parts of motherwort, lock
20 parts of sun, 15 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 25 parts of rhizoma alismatis, 20 parts of Chinese yam;
The concocting method of the present embodiment tablet for chronic nephritis, includes the following steps:
S1, Radix Astragali is cleaned up, dries and is placed in the soak of cellulase, pectase, lignoenzyme mixed
It is filtered after impregnating 1-3h, the alpine yallow herb that obtains that treated;
S2, by ethyl alcohol and pure water by volume 3:2 mixing, stir 1-2min, obtain 60% ethanol solution;
S3,60% ethanol solution for preparing step S1 treated Radix Astragalis and step S2 are according to mass ratio 3:2 are uniformly mixed, close
Standing is closed, stirring is primary per 2-2.2h, and bored profit 35-45h obtains the Radix Astragali moisturized to section;
S4, the Radix Astragali for moisturizing section extract 3 times in 60 °C, and every time plus 60% ethyl alcohol triplication, double quantity and one times are measured, 100 °C
It is evaporated, obtains thick medicinal extract;
S5, RADIX ACONITI LATERALIS PREPARATA, motherwort, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam are attached separately to be impregnated with pure water in container respectively
Piece 10-18min is respectively put into after cleaning in medicine pot, adds the pure water boiling 60min for accounting for pot 2/3,40-70 is placed on after boiling
DEG C climatic chamber drying sterilizing 2-6h, tag, motherwort after being sterilized, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam,
It carries out Ultramicro-powder crushing respectively again, is uniformly mixed, obtains Chinese medicine mixed powder;
S6, Chinese medicine mixed powder prepared by the step S4 Radix Astragali thick medicinal extracts prepared and step S5 is mixed, is stirred evenly, is made
Grain, dry, packaging obtains Shenkangning particle.
Embodiment 2:
The present embodiment tablet for chronic nephritis is made of the raw material of following parts by weight:20 parts of Radix Astragali, 30 parts of RADIX ACONITI LATERALIS PREPARATA, 20 parts of motherwort, lock
20 parts of sun, 15 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 25 parts of rhizoma alismatis, 20 parts of Chinese yam;
The concocting method of the present embodiment tablet for chronic nephritis, includes the following steps:
S1, Radix Astragali is cleaned up, dries and is placed in the soak of cellulase, pectase, lignoenzyme mixed
It is filtered after impregnating 1-3h, the alpine yallow herb that obtains that treated;
S2, by ethyl alcohol and pure water by volume 3:2 mixing, stir 1-2min, obtain 60% ethanol solution;
S3,60% ethanol solution for preparing step S1 treated Radix Astragalis and step S2 are according to mass ratio 3:2 are uniformly mixed, close
Standing is closed, stirring is primary per 2-2.2h, and bored profit 35-45h obtains the Radix Astragali moisturized to section;
S4, the Radix Astragali for moisturizing section extract 3 times in 60 °C, and every time plus 60% ethyl alcohol triplication, double quantity and one times are measured, 100 °C
It is evaporated, obtains thick medicinal extract;
S5, RADIX ACONITI LATERALIS PREPARATA, motherwort, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam are attached separately to be impregnated with pure water in container respectively
Piece 10-18min is respectively put into after cleaning in medicine pot, adds the pure water boiling 60min for accounting for pot 2/3,40-70 is placed on after boiling
DEG C climatic chamber drying sterilizing 2-6h, tag, motherwort after being sterilized, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam,
It carries out Ultramicro-powder crushing respectively again, is uniformly mixed, obtains Chinese medicine mixed powder;
S6, Chinese medicine mixed powder prepared by the step S4 Radix Astragali thick medicinal extracts prepared and step S5 is mixed, is stirred evenly, is made
Grain, it is dry.
S7, the dry particle obtained by step S7 is mixed for 10 parts, tabletting with magnesium stearate, packs, obtains tablet for chronic nephritis.
It should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although ginseng
According to previous embodiment, invention is explained in detail, it will be understood by those of ordinary skill in the art that:It still can be with
Technical scheme described in the above embodiments is modified or equivalent replacement of some of the technical features;And
These modifications or replacements, the spirit and model of various embodiments of the present invention technical solution that it does not separate the essence of the corresponding technical solution
It encloses.
Claims (5)
1. a kind of tablet for chronic nephritis, which is characterized in that the tablet for chronic nephritis is made of the raw material of following parts by weight:12-22 parts of Radix Astragali,
21-35 parts of RADIX ACONITI LATERALIS PREPARATA, 19-28 parts of motherwort, 10-35 parts of cynomorium songaricum, 12-22 parts of Radix Salviae Miltiorrhizae, 18-21 parts of Poria cocos, 20-30 parts of rhizoma alismatis,
15-20 parts of Chinese yam.
2. tablet for chronic nephritis according to claim 1, which is characterized in that the tablet for chronic nephritis by following parts by weight raw material system
At:15-20 parts of Radix Astragali, 25-32 parts of RADIX ACONITI LATERALIS PREPARATA, 20-26 parts of motherwort, 15-30 parts of cynomorium songaricum, 15-20 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos,
22-28 parts of rhizoma alismatis, 18-20 parts of Chinese yam.
3. tablet for chronic nephritis according to claim 1, which is characterized in that the tablet for chronic nephritis by following parts by weight raw material system
At:20 parts of Radix Astragali, 30 parts of RADIX ACONITI LATERALIS PREPARATA, 20 parts of motherwort, 20 parts of cynomorium songaricum, 15 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 25 parts of rhizoma alismatis, Chinese yam 20
Part.
4. the concocting method of tablet for chronic nephritis as described in claim 1-4 is any, which is characterized in that include the following steps:
S1, Radix Astragali is cleaned up, dries and is placed in the soak of cellulase, pectase, lignoenzyme mixed
It is filtered after impregnating 1-3h, the alpine yallow herb that obtains that treated;
S2, by ethyl alcohol and pure water by volume 3:2 mixing, stir 1-2min, obtain 60% ethanol solution;
S3,60% ethanol solution for preparing step S1 treated Radix Astragalis and step S2 are according to mass ratio 3:2 are uniformly mixed, close
Standing is closed, stirring is primary per 2-2.2h, and bored profit 35-45h obtains the Radix Astragali moisturized to section;
S4, the Radix Astragali for moisturizing section extract 3 times in 60 °C, and every time plus 60% ethyl alcohol triplication, double quantity and one times are measured, 100 °C
It is evaporated, obtains thick medicinal extract;
S5, RADIX ACONITI LATERALIS PREPARATA, motherwort, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam are attached separately to be impregnated with pure water in container respectively
Piece 10-18min is respectively put into after cleaning in medicine pot, adds the pure water boiling 60min for accounting for pot 2/3,40-70 is placed on after boiling
DEG C climatic chamber drying sterilizing 2-6h, tag, motherwort after being sterilized, cynomorium songaricum, Radix Salviae Miltiorrhizae, Poria cocos, rhizoma alismatis, Chinese yam,
It carries out Ultramicro-powder crushing respectively again, is uniformly mixed, obtains Chinese medicine mixed powder;
S6, Chinese medicine mixed powder prepared by the step S4 Radix Astragali thick medicinal extracts prepared and step S5 is mixed, is stirred evenly, is made
Grain, it is dry;
S7, it directly packs, or by the dry particle and adhesive, mix lubricant in S6 steps, tabletting obtains tablet for chronic nephritis.
5. the concocting method of tablet for chronic nephritis according to claim 4, which is characterized in that the tablet for chronic nephritis is powder, tablet
In one kind.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20060025990A (en) * | 2004-09-18 | 2006-03-22 | 하현미 | Composition comprising a complex crude extract(bae dang hwan) for preventing and treating diabetes mellitus |
CN102327434A (en) * | 2011-09-23 | 2012-01-25 | 江西普正制药有限公司 | Method for preparing shenkangning capsules |
CN106668431A (en) * | 2017-01-17 | 2017-05-17 | 哈尔滨乐泰药业有限公司 | Traditional Chinese medicine composition with curative effects of warming kidney, invigorating qi and the like, and preparation method and application thereof |
-
2018
- 2018-07-25 CN CN201810829716.0A patent/CN108671117A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20060025990A (en) * | 2004-09-18 | 2006-03-22 | 하현미 | Composition comprising a complex crude extract(bae dang hwan) for preventing and treating diabetes mellitus |
CN102327434A (en) * | 2011-09-23 | 2012-01-25 | 江西普正制药有限公司 | Method for preparing shenkangning capsules |
CN106668431A (en) * | 2017-01-17 | 2017-05-17 | 哈尔滨乐泰药业有限公司 | Traditional Chinese medicine composition with curative effects of warming kidney, invigorating qi and the like, and preparation method and application thereof |
Non-Patent Citations (2)
Title |
---|
中华人民共和国卫生部药典委员会: "《中华人民共和国卫生部 药品标准 中药成方制剂(第六册)》", 31 December 1992 * |
余洪波等: "酶法在中药提取中的研究进展", 《中成药》 * |
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