CN108653682A - A kind of Tibetan medicinal preparation and preparation method thereof for treating nephrosis and diabetes - Google Patents
A kind of Tibetan medicinal preparation and preparation method thereof for treating nephrosis and diabetes Download PDFInfo
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- CN108653682A CN108653682A CN201810873528.8A CN201810873528A CN108653682A CN 108653682 A CN108653682 A CN 108653682A CN 201810873528 A CN201810873528 A CN 201810873528A CN 108653682 A CN108653682 A CN 108653682A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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Abstract
The invention discloses a kind of Tibetan medicinal preparation and preparation method thereof for treating nephrosis and diabetes, preparation is made of the raw material of following parts by weight content：46 54 parts of myrobalan, 23 28 parts of conic gymnadenia tuber, 23 28 parts of turmeric, 23 28 parts of safflower, 37 parts of bear gall, 13 16 parts of cinnabar, 22 27 parts of Lagotis brachystachya Maxim.The present invention is formulated in accordance with ancient method sorting, processing according to " Six-element, eight property, 17 effects " are theoretical.Conic gymnadenia tuber Yishen Jianpi in side, qi-regulating and blood, myrobalan's relieving diarrhea with astringents, chronic cough are more than, safflower invigorate blood circulation, removing blood stasis and analgesics, turmeric blood-breaking, relieving pain of dysmenorrhea, and cinnabar clears away heart-fire calmness, tranquilizing the mind, item, removing toxic substances, Lagotis brachystachya Maxim removing heat from the lung to relieve cough, decompression menstruation regulating.It supplements the deficiency of existing drug therapy, reasonable recipe, and all medicines play adjusting three because of disorder, have the effect of kidney-nourishing, controlling nocturnal emission with astringent drugs, diuresis altogether.Clinically there is good therapeutic effect to nephrosis and diabetes, securely and reliably.There is preferable protection therapeutic effect for the various complication such as urgent urination, turbid urine, seminal emission.
Description
Technical field
The invention belongs to Tibetan medicine technical fields, and in particular to a kind of Tibetan medicinal preparation that treating nephrosis and diabetes and its preparation
Method.
Background technology
Tibetan medicine, it is with a long history, it is to live in during Qinghai-Tibet people struggle with the Nature gradually to recognize one
A little substances derived from plant, animal and mineral can be used for disease treatment and health with certain pharmacological action；It is wide
It is general to absorb, merged traditional Chinese medicine and pharmacy, on the basis of Indian Medicinal and big dietitian's pharmacy scheduling theory, pass through long-term practice formation
Unique medicine systems are one of the ethnic drugs that China is more complete, influence power highlights.It experienced thousands of years of developing history
Afterwards, with China reform and open up to the outside world paces, also step into the great development stage, shine unprecedented life and vigor, not only at
For a dazzling jewel in traditional Chinese medicine treasure-house, and it is exported to international market, application range is also no longer limited to send out
Source.
Currently, with the allegro development of society, the various pressure that one side people are born are increasing, nephrosis and diabetes
Illness rate in steeply rising situation.On the other hand with people's living standards continue to improve, to the general level of the health of itself
Increasingly pay attention to.Treatment nephrosis and diabetes are mostly with Chinese medicine and Western medicine therapy at present.Though having the effect of certain, therapy
Limited with drug, western medicine side effect is big, still has some patientss not improve after Chinese medicine or doctor trained in Western medicine systematic treating or good
Turn unobvious.This present situation will promote to find safely and effectively drug and therapy is used for treating nephrosis and compels in eyebrow with diabetes
Eyelash.
Invention content
The purpose of the present invention is to solve the technical problems existing in the prior art, a kind of reasonable recipe, curative effect are provided
Significantly, the Tibetan medicinal preparation of safe and reliable treatment nephrosis and diabetes.
It is a further object to provide a kind of preparation methods of Tibetan medicinal preparation that treating nephrosis and diabetes.
In order to achieve the above object, the present invention uses following technical scheme：A kind of Tibetan medicine system for treating nephrosis and diabetes
Agent is made of the raw material of following parts by weight content：46-54 parts of myrobalan, 23-28 parts of conic gymnadenia tuber, 23-28 parts of turmeric, safflower 23-28
Part, 3-7 parts of bear gall, 13-16 parts of cinnabar, 22-27 parts of Lagotis brachystachya Maxim.
Further, a kind of Tibetan medicinal preparation for treating nephrosis and diabetes is made of the raw material of following parts by weight content：It scolds
50 parts of son, 25 parts of conic gymnadenia tuber, 25 parts of turmeric, 25 parts of safflower, 5 parts of bear gall, 15 parts of cinnabar, 25 parts of Lagotis brachystachya Maxim.
A kind of preparation method of Tibetan medicinal preparation that treating nephrosis and diabetes, this approach includes the following steps：
A, bulk pharmaceutical chemicals are prepared：Each raw material in formula removes the pre-treatment principle of different cultivars ingredient requirement according to Tibetan medicine
Non- medicinal effects and impurity reach the required standard of production；
B, fine powder is prepared：Each bulk pharmaceutical chemicals after processing of step A are weighed according to the amount in formula, by myrobalan, cinnabar according to tradition
Processing method carries out processing processing, and conic gymnadenia tuber, turmeric, safflower, bear gall, Lagotis brachystachya Maxim are crushed and pass through high-efficiency screening machine
Sieving obtains fine powder；
C, it mixes：By each fine powder being prepared and process treated myrobalan and cinnabar after mixing up to treatment nephrosis with
The Tibetan medicinal preparation of diabetes.
Further, high-efficiency screening machine screen mesh is 100 mesh in the step B.
The present invention has the advantages that compared with the prior art：The present invention treats nephrosis and the Tibetan medicinal preparation of diabetes is abided by
It according to ancient method sorting, processes, is formulated according to " Six-element, eight property, 17 effects " are theoretical.By myrobalan, conic gymnadenia tuber, turmeric, safflower, bear gall,
Totally seven taste Tibetan medicine materials form for cinnabar, Lagotis brachystachya Maxim, conic gymnadenia tuber Yishen Jianpi, qi-regulating and blood in side, myrobalan's relieving diarrhea with astringents, chronic cough
Incessantly, safflower invigorate blood circulation, removing blood stasis and analgesics, turmeric blood-breaking, relieving pain of dysmenorrhea, cinnabar clear away heart-fire calmness, tranquilizing the mind, item, removing toxic substances,
Lagotis brachystachya Maxim removing heat from the lung to relieve cough, decompression menstruation regulating.It supplements the deficiency of existing drug therapy, reasonable recipe, and all medicines play adjusting altogether
Three, because of disorder, have the effect of kidney-nourishing, controlling nocturnal emission with astringent drugs, diuresis.Clinically there is good therapeutic effect, curative effect to nephrosis and diabetes
Significantly, securely and reliably.There is preferable protection therapeutic effect for the various complication such as urgent urination, turbid urine, seminal emission.
Specific implementation mode
The present invention is further explained in the light of specific embodiments.
Embodiment 1
A kind of Tibetan medicinal preparation for treating nephrosis and diabetes, is made of the raw material of following weight content：Myrobalan 46g, conic gymnadenia tuber
28g, turmeric 23g, safflower 28g, bear gall 3g, cinnabar 16g, Lagotis brachystachya Maxim 22g.
Embodiment 2
A kind of Tibetan medicinal preparation for treating nephrosis and diabetes, is made of the raw material of following weight content：Myrobalan 54g, conic gymnadenia tuber
23g, turmeric 28g, safflower 23g, bear gall 7g, cinnabar 13g, Lagotis brachystachya Maxim 27g.
Embodiment 3
A kind of Tibetan medicinal preparation for treating nephrosis and diabetes, is made of the raw material of following weight content：Myrobalan 50g, conic gymnadenia tuber
25g, turmeric 25g, safflower 25g, bear gall 5g, cinnabar 15g, Lagotis brachystachya Maxim 25g.
When being prepared to the Tibetan medicinal preparation of above-described embodiment, include the following steps：
A, bulk pharmaceutical chemicals are prepared：Each raw material in formula removes the pre-treatment principle of different cultivars ingredient requirement according to Tibetan medicine
Non- medicinal effects and impurity reach the required standard of production.
B, fine powder is prepared：Weigh each bulk pharmaceutical chemicals after processing of step A according to the amount in formula, by myrobalan, cinnabar according to
Traditional diamond-making technique carries out processing processing, and conic gymnadenia tuber, turmeric, safflower, bear gall, Lagotis brachystachya Maxim are crushed and pass through high-efficiency sieve
Extension set is sieved to obtain fine powder, and the wherein screen mesh of high-efficiency screening machine is 100 mesh.
C, it mixes：By each fine powder being prepared and treated myrobalan and cinnabar are processed after mixing up to treatment kidney
The Tibetan medicinal preparation of disease and diabetes.
The Tibetan medicinal preparation of above-described embodiment can use mixing in water for oral taking, and suitable quantity of water can also be added and make pill.
Clinical test：
One, case-data：
The foundation of preparation clinical research methods is to combine modern traditional Chinese and western medicine Clinical Study Protocol according to Tibetan medicine and pharmacology theoretical system, according to
Preparation target user, takes the course for the treatment of, it is determined that Clinical Study Protocol.Define the inclusion criteria, control drug, Bing Renji of case history
It checks, therapeutic evaluation, adverse reaction etc., passes through after the inspection of plinth sign, the inspection of feature biochemical indicator, medication course, period and medication
The validity of statistical analysis Scientific evaluation preparation.Observation 124 altogether, man 70, female 54, age：26-73 Sui, course of disease 1-7
Year.
Above-mentioned patient is randomly divided into two groups：I group（Treatment group）, II group（Control group）.Every group 62, two groups of genders, years
Age, the course of disease etc., there was no significant difference.
Two, therapy：
（One）The preparation of drug：
Prepare medicine A and medicine B, Chinese medicine A is that Tibetan medicinal preparation made from the embodiment of the present invention 3 adds pill made of suitable quantity of water.Medicine B is
Diabecron sustained-release tablet+Gliquidone.
（Two）Medication：
II group（Control group）：Medicine B.
II group（Control group）According to dosage take diabecron sustained-release tablet+Gliquidone, diabecron sustained-release
Piece：Hainan Hai Li pharmaceutical Co. Ltds【Authentication code】：Chinese medicines quasi-word H20050070, Gliquidone：The double cranes of ten thousand brightness of Beijing
Medicine company Co., Ltd【Authentication code】：Chinese medicines quasi-word H10940258.January is as a treatment course, and it is laggard that 3 courses for the treatment of are used in conjunction
Row Comparison of therapeutic.
I group（Treatment group）：Medicine A.
I group（Treatment group）Patient gives Tibetan medicinal preparation made from the embodiment of the present invention 3 and adds pill made of suitable quantity of water oral
Treatment, the weight 0.08g per ball, daily after early postprandial, lunch, after dinner, each taking 20 balls.One month is 1 course for the treatment of, is used in conjunction 3
Comparison of therapeutic is carried out after a course for the treatment of.
It is avoided during treatment into irritative foods such as supercooling, overheat, sugar contents.Clinical symptoms of every three weekly check, body
The inspection of sign, blood glucose etc. after treatment end, that is, carries out Short Term Clinical curative effect summary, and with regard to clinical manifestation and side effect etc.
It is compared analysis.
Three, curative effect judging standard：
It cures：Clinical symptoms disappear, and blood glucose level gradually restores normal.
It improves：Clinical symptoms are substantially reduced, and blood glucose is steady.
In vain：The pretherapy and post-treatment state of an illness is without significant change person.
Four, statistical method：
Data processing carries out statistical analysis with spss13.0 softwares, and enumeration data is examined using X2（P ﹤ 0.05 have for difference
It is statistically significant）.
Five, result：
I group（Treatment group）With II group（Control group）Patient clinical curative effect is relatively shown in Table 1.
Table 1：Two groups of patient clinical curative effects compare
Six, overall merit：
By clinical test, treatment group is with obvious effects to be better than control group, reaches pole significant difference, total effective rate is facing up to 95.2%
In terms of bed symptom improvement, preferable efficient and cure rate is shown, adverse reaction does not occur, demonstrates Tibetan medicine tradition doctor
Science.
Claims (4)
1. a kind of Tibetan medicinal preparation for treating nephrosis and diabetes, it is characterised in that：It is made of the raw material of following parts by weight content：It scolds
46-54 parts sub-, 23-28 parts of conic gymnadenia tuber, 23-28 parts of turmeric, 23-28 parts of safflower, 3-7 parts of bear gall, 13-16 parts of cinnabar, short fringe
22-27 parts of Lagotis glauca.
2. a kind of Tibetan medicinal preparation for treating nephrosis and diabetes according to claim 1, it is characterised in that：By following weight
The raw material composition of part content：50 parts of myrobalan, 25 parts of conic gymnadenia tuber, 25 parts of turmeric, 25 parts of safflower, 5 parts of bear gall, 15 parts of cinnabar,
25 parts of Lagotis brachystachya Maxim.
3. a kind of preparation method of Tibetan medicinal preparation that treating nephrosis and diabetes, it is characterised in that：This approach includes the following steps：
A, bulk pharmaceutical chemicals are prepared：Each raw material in formula removes the pre-treatment principle of different cultivars ingredient requirement according to Tibetan medicine
Non- medicinal effects and impurity reach the required standard of production；
B, fine powder is prepared：Each bulk pharmaceutical chemicals after processing of step A are weighed according to the amount in formula, by myrobalan, cinnabar according to tradition
Processing method carries out processing processing, and conic gymnadenia tuber, turmeric, safflower, bear gall, Lagotis brachystachya Maxim are crushed and pass through high-efficiency screening machine
Sieving obtains fine powder；
C, it mixes：By each fine powder being prepared and process treated myrobalan and cinnabar after mixing up to treatment nephrosis with
The Tibetan medicinal preparation of diabetes.
4. a kind of preparation method of Tibetan medicinal preparation for treating nephrosis and diabetes according to claim 3, it is characterised in that：
High-efficiency screening machine screen mesh is 100 mesh in the step B.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810873528.8A CN108653682A (en) | 2018-08-02 | 2018-08-02 | A kind of Tibetan medicinal preparation and preparation method thereof for treating nephrosis and diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810873528.8A CN108653682A (en) | 2018-08-02 | 2018-08-02 | A kind of Tibetan medicinal preparation and preparation method thereof for treating nephrosis and diabetes |
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| Publication Number | Publication Date |
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| CN108653682A true CN108653682A (en) | 2018-10-16 |
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ID=63788907
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810873528.8A Pending CN108653682A (en) | 2018-08-02 | 2018-08-02 | A kind of Tibetan medicinal preparation and preparation method thereof for treating nephrosis and diabetes |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101269198A (en) * | 2008-02-29 | 2008-09-24 | 西藏嘉黎县藏医院 | Pure Chinese medicine preparation for preventing and treating enteron disease and improving self phylactic power, and preparation method thereof |
-
2018
- 2018-08-02 CN CN201810873528.8A patent/CN108653682A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101269198A (en) * | 2008-02-29 | 2008-09-24 | 西藏嘉黎县藏医院 | Pure Chinese medicine preparation for preventing and treating enteron disease and improving self phylactic power, and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 张耕 等: "《常用中药毒性研究进展及应用》", 30 September 2013, 湖北科学技术出版社 * |
| 徐元贞 等: "《中华方药宝典》", 31 March 2012, 河南科学技术出版社 * |
| 徐榕青: "《福建道地药材现代研究》", 31 October 2014, 福建科学技术出版社 * |
| 杨卫平 等: "《特色中草药及配方.6》", 31 August 2016, 中国中医药出版社 * |
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Application publication date: 20181016 |