CN108653519A - 一种肌肉损伤的喷雾剂配方及其制作工艺 - Google Patents

一种肌肉损伤的喷雾剂配方及其制作工艺 Download PDF

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CN108653519A
CN108653519A CN201810523313.3A CN201810523313A CN108653519A CN 108653519 A CN108653519 A CN 108653519A CN 201810523313 A CN201810523313 A CN 201810523313A CN 108653519 A CN108653519 A CN 108653519A
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张桂芳
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Abstract

一种治疗肌肉损伤药物的喷雾剂配方及其制作工艺，涉及医疗卫生领域，具体涉及一种治疗肌肉疲劳、碰伤、拉伤症状的药物喷雾剂配方及其制作工艺。一种治疗肌肉损伤药物的喷雾剂配方为以下原药材组成：红花、香附份、川牛膝、川芎、八角、白芷、没药、牡丹皮、冰片、威灵仙、防风、薄荷油；它的制作工艺包括以下几个步骤：第一步，晒干；第二步，搅拌过30目筛（除薄荷油外）；第三步，浸泡发酵；第四步，用滤网将药渣过滤，取过滤后的药材药液；第五步，将薄荷油混入药液搅拌后密封静置1小时；第六步，装瓶。它是一种纯中药的外用喷雾剂，通过外皮吸收达到病灶，起到较好的治疗效果，用药5‑10分钟后疼痛减轻，一天后就可以正常活动和工作。

Description

一种肌肉损伤的喷雾剂配方及其制作工艺
技术领域
本发明涉及一种治疗肌肉损伤药物的喷雾剂配方及其制作工艺，涉及医疗卫生领域，具体涉及一种治疗肌肉疲劳、碰伤、拉伤症状的药物喷雾剂配方及其制作工艺。
背景技术
由于气候环境、工作环境、工作习惯及个人身体素质的原因，尤其是运动时容易造成个人的腰部、手臂及腿部肌肉造成不同程度的疲劳、碰伤及拉伤症状。
根据个人受创程度的不同，人们通常选择热敷、按摩、帖伤痛药膏、喷涂药剂等方式来进行缓解或治疗，但是简单的热敷、按摩方式见效通常较慢，一般的药膏、药剂治疗效果也不明显，见效快的治疗药物价格又过于昂贵，一些药物的使用方式也无法适用于每一个人，这些都给患者的治疗带来了许多不便。
发明内容
本发明的目的在于针对现有技术的缺陷和不足，提供一种治疗肌肉疲劳、碰伤、拉伤症状的药物喷雾剂配方及其制作工艺，制作简单，成本较低，使用方便。
为实现上述目的，本发明采用以下技术方案是：一种治疗肌肉损伤药物的喷雾剂配方为以下原药材组成：红花8-10份、香附5-7份、川牛膝2-4份、川芎4-6份、八角2-4份、白芷6-8份、没药6-8份、牡丹皮3-5份、冰片8-10份、威灵仙1-3份、防风3-5份、薄荷油3-5份；它的制作工艺包括以下几个步骤：第一步，按计量配比将以上药材筛选过后均匀摊开晒干；第二步，将晒干后的药材混合并粉碎搅拌过30目筛（除薄荷油外）；第三步，将药材粉末倒入容器中，加入10度米醋600ml浸泡发酵，发酵期间需避光保持温度在25-30度，发酵时间为一个月；第四步，用滤网将药渣过滤，取过滤后的药材药液；第五步，将薄荷油混入药液搅拌后密封静置1小时；第六步，将药液装瓶，每600ml药液可封装二瓶使用。
进一步的，所述的搅拌时长为30分钟。
进一步的，所述的容器为密封容器。
采用上述技术方案后，本发明有益效果为：它是一种纯中药的外用喷雾剂，只需喷涂在患者的病痛处，通过外皮吸收达到病灶，起到较好的治疗效果，用药5-10分钟后疼痛减轻，一天后就可以正常活动和工作。
具体实施方式
实施例1
本具体实施方式采用的技术方案是：一种治疗肌肉损伤药物的喷雾剂配方为以下原药材组成：红花8份、香附5份、川牛膝2份、川芎4份、八角2份、白芷6份、没药6份、牡丹皮3份、冰片8份、威灵仙1份、防风3份、薄荷油3份；它的制作工艺包括以下几个步骤：第一步，按计量配比将以上药材筛选过后均匀摊开晒干；第二步，将晒干后的药材混合并粉碎搅拌过30目筛（除薄荷油外）；第三步，将药材粉末倒入容器中，加入10度米醋600ml浸泡发酵，发酵期间需避光保持温度在25-30度，发酵时间为一个月；第四步，用滤网将药渣过滤，取过滤后的药材药液；第五步，将薄荷油混入药液搅拌后密封静置1小时；第六步，将药液装瓶，每600ml药液可封装二瓶使用。
红花有治疗经闭、痛经、恶露不行、胸痹心痛、瘀滞腹痛、胸胁刺痛、跌打损伤、疮疡肿痛的功效。
没药有活血止痛、消肿生肌等功效。
川牛膝具有逐瘀通经、通利关节、利尿通淋等功效。
川芎用于月经不调、经闭痛经、产后瘀滞腥痛；症瘕肿块、胸胁疼痛、头痛眩晕、风寒湿痹、跌打损伤、痈疽疮疡等。
白芷具有祛风湿、活血排脓、生肌止痛功效。
牡丹皮具有清热凉血、活血化淤、退虚热等功效。
防风有祛风解表、胜湿止痛、止痉的功效。
冰片有通诸窍、散郁火、去翳明目、消肿止痛的功效。
威灵仙有祛风除湿、通络止痛、消痰水、散癖积的功效。
实施例2
一种治疗肌肉损伤药物的喷雾剂配方为以下原药材组成：红花9份、香附6份、川牛膝3份、川芎5份、八角3份、白芷7份、没药7份、牡丹皮4份、冰片9份、威灵仙2份、防风4份、薄荷油4份。
其它原料组成、制备方法均与实施例1相同。
实施例3
一种治疗肌肉损伤药物的喷雾剂配方为以下原药材组成：红花10份、香附7份、川牛膝4份、川芎6份、八角4份、白芷8份、没药8份、牡丹皮5份、冰片10份、威灵仙3份、防风5份、薄荷油5份。
其它原料组成、制备方法均与实施例1相同。
采用上述技术方案后，本发明有益效果为：它是一种纯中药的外用喷雾剂，只需喷涂在患者的病痛处，通过外皮吸收达到病灶，起到较好的治疗效果，用药5-10分钟后疼痛减轻，一天后就可以正常活动和工作。
以上所述，仅用以说明本发明的技术方案而非限制，本领域普通技术人员对本发明的技术方案所做的其它修改或者等同替换，只要不脱离本发明技术方案的精神和范围，均应涵盖在本发明的权利要求范围当中。

Claims (6)

1.一种治疗肌肉损伤药物的喷雾剂配方，其特征在于它由以下重量份数的原药材组成：红花8-10份、香附5-7份、川牛膝2-4份、川芎4-6份、八角2-4份、白芷6-8份、没药6-8份、牡丹皮3-5份、冰片8-10份、威灵仙1-3份、防风3-5份、薄荷油3-5份。
2.一种治疗肌肉损伤药物的喷雾剂制作工艺，其特征在于它的制作工艺包含以下几个步骤：第一步，按计量配比将以上药材筛选过后均匀摊开晒干；第二步，将晒干后的药材混合并粉碎搅拌过30目筛（除薄荷油外）；第三步，将药材粉末倒入容器中，加入10度米醋600ml浸泡发酵，发酵期间需避光保持温度在25-30度，发酵时间为一个月；第四步，用滤网将药渣过滤，取过滤后的药材药液；第五步，将薄荷油混入药液搅拌后密封静置1小时；第六步，将药液装瓶，每600ml药液可封装二瓶使用。
3.根据权利要求1所述的一种治疗肌肉损伤药物的喷雾剂配方，其特征在于它由以下重量份数的原药材组成：红花9份、香附6份、川牛膝3份、川芎5份、八角3份、白芷7份、没药7份、牡丹皮4份、冰片9份、威灵仙2份、防风4份、薄荷油4份。
4.根据权利要求1所述的一种治疗肌肉损伤药物的喷雾剂配方，其特征在于它由以下重量份数的原药材组成：红花10份、香附7份、川牛膝4份、川芎6份、八角4份、白芷8份、没药8份、牡丹皮5份、冰片10份、威灵仙3份、防风5份、薄荷油5份。
5.根据权利要求2所述的一种治疗肌肉损伤药物的喷雾剂制作工艺，其特征在于：所述的搅拌时长为30分钟。
6.根据权利要求2所述的一种治疗肌肉损伤药物的喷雾剂制作工艺，其特征在于：容器为密封容器。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109045174A (zh) * 2018-10-29 2018-12-21 乌鲁木齐凯德道诚信息咨询服务有限公司 一种骨病擦剂药物配方及其制作工艺

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101062227A (zh) * 2007-05-21 2007-10-31 王军 香附活血丸
CN107812047A (zh) * 2017-11-02 2018-03-20 广州誉嘉生物科技有限公司 一种用于治疗跌打损伤的药物组合物及其应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101062227A (zh) * 2007-05-21 2007-10-31 王军 香附活血丸
CN107812047A (zh) * 2017-11-02 2018-03-20 广州誉嘉生物科技有限公司 一种用于治疗跌打损伤的药物组合物及其应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
邓志洪: "十味活血丸治疗急性软组织损伤的临床观察", 《中国中医骨伤科杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109045174A (zh) * 2018-10-29 2018-12-21 乌鲁木齐凯德道诚信息咨询服务有限公司 一种骨病擦剂药物配方及其制作工艺

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