CN108651450A - A kind of composition for the processing of hearing aid surface long-acting bacteriostatic - Google Patents
A kind of composition for the processing of hearing aid surface long-acting bacteriostatic Download PDFInfo
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- CN108651450A CN108651450A CN201810407179.0A CN201810407179A CN108651450A CN 108651450 A CN108651450 A CN 108651450A CN 201810407179 A CN201810407179 A CN 201810407179A CN 108651450 A CN108651450 A CN 108651450A
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Abstract
The present invention relates to technical field of biological materials, and in particular to a kind of composition for the processing of hearing aid surface long-acting bacteriostatic.The ingredient of the composition includes the first bactericidal composition, the second bactericidal composition and organic solution；Wherein, the ingredient of the first bactericidal composition includes：The big acetic acid ferrisodium of decamethylene biguanides dihydrochloride, two salicyl of ethylenediamine, amino-oligosacchride substance, lavo-ofloxacin, Tinidazole, N N-isopropylacrylamides, potassium peroxydisulfate, N, N dimethacrylamide, gelatin, cyclodextrin and water；The ingredient of second bactericidal composition includes：Sodium silicate solution, sodium bicarbonate solution, nano-silver powder, nano-titanium dioxide, dilute sulfuric acid and saturation sodium nitrate；The type bacteria inhibiting composition skin-friendly is good, safe and non-toxic, can be used for entering ear material to hearing aid and is surface-treated, and makes it have long-acting antibacterial, bacteria-eliminating efficacy.
Description
Technical field
The present invention relates to technical field of biological materials, and in particular to a kind of group for the processing of hearing aid surface long-acting bacteriostatic
Close object.
Background technology
Hearing aid is the accessory that person hard of hearing uses, and for supplying the defect caused by hearing impairment, and then improves and listens
Hinder the instrument of personage and conference communicative competence.Hearing aid is exactly an electroacoustic amplifier, and sound amplification is made deaf person by it
It has heard and can not hear clearly originally, the sound that can't hear.Currently, hearing aid is broadly divided into simulation hearing aid and digital deaf-aid two
Kind.No matter wherein simulation hearing aid is the hearing loss curve shape patient, carries out unified amplification to sound, and digital hearing aid
Device is precisely compensated for according to the hearing loss curve shape of patient.Hearing aid is divided into ear-level hearing aid, and inner ear type helps
Listen device, duct-type hearing aid, complete duct-type hearing aid, stealthy hearing aid etc..
Wherein, since most of hearing aids need to be placed on ear canal internal use, it is therefore desirable to hold the pleasant material of hearing aid
Otherwise the sanitation and hygiene for expecting surface easily cause infection, cause the diseases such as tympanitis, otitis externa, but conventional hearing aid enters
Ear material does not have degerming fungistatic effect, needs often to take out progress sterilizing, very cumbersome.
Invention content
For problems of the prior art, being used for what hearing aid surface long-acting bacteriostatic was handled the present invention provides a kind of
Composition, the composition, which can be used for entering ear material to hearing aid, to be surface-treated, and makes it have long-acting antibacterial, degerming effect
Fruit.
In order to achieve the above object, the present invention is achieved through the following technical solutions：
A kind of composition for the processing of hearing aid surface long-acting bacteriostatic, it is characterised in that；The composition at subpackage
Include the first bactericidal composition, the second bactericidal composition and organic solution；
Wherein, according to mass fraction, the ingredient of the first bactericidal composition includes：
4-5 parts of decamethylene biguanides dihydrochloride, 0.4-1.5 parts of two salicyl of ethylenediamine big acetic acid ferrisodium, amino are few
7-10 parts of glucide, 5-10 parts of lavo-ofloxacin, 3-6 parts of Tinidazole, 3-5 parts of n-isopropyl acrylamide, potassium peroxydisulfate
0.1-0.12 parts, 0.4-0.7 parts of N,N-DMAA, 6-8 parts of gelatin, 3-5 parts of cyclodextrin, 70-85 parts of water.
The ingredient of second bactericidal composition includes：
15-20 parts of 20% sodium silicate solution, 20-25 parts of 10% sodium bicarbonate solution, 0.5-0.8 parts of nano-silver powder,
1.5-2 parts of nano-titanium dioxide, 1-3 parts of 45% dilute sulfuric acid are saturated 7-9 parts of sodium nitrate.
The ingredient of organic solution includes：
4-8 parts of polylactic acid, 4-7 parts of polycaprolactone, 5-7 parts, N of Poly(D,L-lactide-co-glycolide, N- dimethylpropionamides
15-19 parts, 30-40 parts of acetone.
Preferably, according to mass fraction, the ingredient of the first bactericidal composition includes：Decamethylene biguanides dihydrochloride 4.2-
4.4 parts, 0.8-1.1 parts of two salicyl of ethylenediamine big acetic acid ferrisodium, 8-9 parts of amino-oligosacchride substance, lavo-ofloxacin 6-7
Part, 4-5 parts of Tinidazole, 3-4 parts of n-isopropyl acrylamide, 0.11-0.12 parts of potassium peroxydisulfate, N,N-DMAA
0.5-0.6 parts, 7-8 parts of gelatin, 3-4 parts of cyclodextrin, 80-82 parts of water.
Preferably, according to mass fraction, the ingredient of the second bactericidal composition includes：17-18 parts of 20% sodium silicate solution,
22-23 parts of 10% sodium bicarbonate solution, 0.6-0.7 parts of nano-silver powder, 1.7-1.8 parts of nano-titanium dioxide, 45% dilute sulphur
It is 2.4-2.6 parts sour, it is saturated 8-9 parts of sodium nitrate.
Preferably, according to mass fraction, the ingredient of organic solution includes：6-7 parts of polylactic acid, 5-6 parts of polycaprolactone gather breast
Acid -5-6 parts of co-glycolic acid, N, 17-18 parts of N- dimethylpropionamides, 35-37 parts of acetone.
Preferably, amino-oligosacchride substance includes：One or more mixing in streptomysin, gentamicin, neomycin
Object.
The preparation of bacteria inhibiting composition provided by the invention includes the following steps：
(1) according to mass fraction, in an aseptic environment, gelatin and cyclodextrin are dissolved in water at room temperature, then will
N-isopropyl acrylamide, potassium peroxydisulfate, N,N-DMAA are added in solution, and mixed solution heating water bath is extremely
65-70 DEG C, and be slowly stirred with the rotating speed of 90-100r/min, during stirring gradually by decamethylene biguanides dihydrochloride,
The big acetic acid ferrisodium of two salicyl of ethylenediamine, amino-oligosacchride substance, lavo-ofloxacin and Tinidazole are added in solution, are continued
2.5-3h is stirred, colloidal substance is obtained, by colloidal substance centrifuge washing, obtains required first bactericidal composition.
(2) according to mass fraction, in an aseptic environment, sodium silicate solution is heated to 75-85 DEG C under water bath, by
It is added dropwise to sodium bicarbonate solution, and is slowly stirred with the rotating speed of 100-130r/min, 15-20min is reacted, then with dilute sulfuric acid tune
The pH value for saving solution is 5-6, and nano-silver powder and nano-titanium dioxide are dissolved in the solution, and saturation nitric acid is added dropwise into solution
Jello is made after salting liquid reaction, by the object centrifuge washing that is gelled, had both obtained required second bactericidal composition.
(3) according to mass fraction, in an aseptic environment, by N, N- dimethylpropionamides and acetone are uniformly mixing to obtain miscible
Then polylactic acid, polycaprolactone and Poly(D,L-lactide-co-glycolide are added in the mixed solvent, are stirred at room temperature by agent
40-60min obtains required organic solution.
(4) according to 3:1:The first bactericidal composition, the second bactericidal composition are added in an aseptic environment for 8 mass ratio
It into organic solution, is handled with the rotating speed high speed dispersion of 800-950r/min, obtains institute required to hearing aid surface long-acting bacteriostatic
The composition of processing.
Bacteria inhibiting composition provided by the invention is used for the antibacterial processing method in hearing aid surface：With high-pressure electrostatic coating
Composition is coated uniformly on the surface that hearing aid enters ear material by mode, and hearing aid, which is then entered ear material, is sent to vacuum drying
In case, 20-25h is dried with 25-30 DEG C of thermostatic, obtains required long-acting bacteriostatic treated hearing aid.
The present invention has following advantageous effect：
The surface that the composition material can be used for entering hearing aid ear material is handled so that it is with long-acting suppression
Bacterium bacteria-eliminating efficacy wherein composition include with a variety of antibacterials and except the first bactericidal composition based on mushroom chemicals, with
And the second bactericidal composition based on nano-silver powder and nano-titanium dioxide, degerming antibacterial substance pass through gel-like constituent
After the processing of organic principle, the stabilization of physicochemical properties can be both kept, there is good adhesion effect and long-acting slow
Release effect；Long-acting bacteriostat degerming effect can be played in the pleasant material surface of hearing aid.Wherein, the composition ingredient and human body
Between have good compatibility, ear canal internal will not be caused to stimulate, it is very safe and healthy.
Specific implementation mode
The specific implementation mode of the present invention is further described with reference to embodiment, following embodiment is only used for more
Technical scheme of the present invention is clearly demonstrated, and not intended to limit the protection scope of the present invention.
Embodiment 1
A kind of composition for the processing of hearing aid surface long-acting bacteriostatic, it is characterised in that；The composition at subpackage
Include the first bactericidal composition, the second bactericidal composition and organic solution；
According to mass fraction, the ingredient of the first bactericidal composition includes：
4 parts of decamethylene biguanides dihydrochloride, 0.4 part of the big acetic acid ferrisodium of two salicyl of ethylenediamine, amino-oligosacchride class object
7 parts of matter, 5 parts of lavo-ofloxacin, 3 parts of Tinidazole, 3 parts of n-isopropyl acrylamide, 0.1 part, N of potassium peroxydisulfate, N- dimethyl propylenes
0.4 part of acrylamide, 6 parts of gelatin, 3 parts of cyclodextrin, 70 parts of water.
The ingredient of second bactericidal composition includes：
15 parts of 20% sodium silicate solution, 20 parts of 10% sodium bicarbonate solution, 0.5 part of nano-silver powder, nanometer titanium dioxide
1.5 parts of titanium, 1 part of 45% dilute sulfuric acid are saturated 7 parts of sodium nitrate.
The ingredient of organic solution includes：
4 parts of polylactic acid, 4 parts of polycaprolactone, 5 parts, N of Poly(D,L-lactide-co-glycolide, 15 parts of N- dimethylpropionamides,
30 parts of acetone.
Wherein, amino-oligosacchride substance includes：The mixture of streptomysin and neomycin.
The preparation of bacteria inhibiting composition in the present embodiment includes the following steps：
(1) according to mass fraction, in an aseptic environment, gelatin and cyclodextrin are dissolved in water at room temperature, then will
N-isopropyl acrylamide, potassium peroxydisulfate, N,N-DMAA are added in solution, mixed solution heating water bath to 65
DEG C, and be slowly stirred with the rotating speed of 90r/min, gradually by decamethylene biguanides dihydrochloride, ethylenediamine two during stirring
The big acetic acid ferrisodium of salicyl, amino-oligosacchride substance, lavo-ofloxacin and Tinidazole are added in solution, lasting to stir
2.5h obtains colloidal substance, by colloidal substance centrifuge washing, obtains required first bactericidal composition.
(2) according to mass fraction, in an aseptic environment, sodium silicate solution is heated to 75 DEG C under water bath, dropwise
Sodium bicarbonate solution is added, and is slowly stirred with the rotating speed of 100r/min, reacts 15min, then adjusts solution with dilute sulfuric acid
PH value is 5, and nano-silver powder and nano-titanium dioxide are dissolved in the solution, and saturation nitrate solution reaction is added dropwise into solution
Jello is made afterwards, by the object centrifuge washing that is gelled, had both obtained required second bactericidal composition.
(3) according to mass fraction, in an aseptic environment, by N, N- dimethylpropionamides and acetone are uniformly mixing to obtain miscible
Then polylactic acid, polycaprolactone and Poly(D,L-lactide-co-glycolide are added in the mixed solvent, are stirred at room temperature by agent
40min obtains required organic solution.
(4) according to 3:1:The first bactericidal composition, the second bactericidal composition are added in an aseptic environment for 8 mass ratio
It into organic solution, is handled with the rotating speed high speed dispersion of 800r/min, obtains institute required to the processing of hearing aid surface long-acting bacteriostatic
Composition.
Bacteria inhibiting composition provided in this embodiment is used for the antibacterial processing method in hearing aid surface：It is coated with high-pressure electrostatic
Mode composition is coated uniformly on the surface that hearing aid enters ear material, hearing aid then entered ear material be sent to vacuum to do
In dry case, 20h is dried with 25 DEG C of thermostatic, obtains required long-acting bacteriostatic treated hearing aid.
Embodiment 2
A kind of composition for the processing of hearing aid surface long-acting bacteriostatic, it is characterised in that；The composition at subpackage
Include the first bactericidal composition, the second bactericidal composition and organic solution；
According to mass fraction, the ingredient of the first bactericidal composition includes：
5 parts of decamethylene biguanides dihydrochloride, 1.5 parts of the big acetic acid ferrisodium of two salicyl of ethylenediamine, amino-oligosacchride class object
10 parts of matter, 10 parts of lavo-ofloxacin, 6 parts of Tinidazole, 5 parts of n-isopropyl acrylamide, 0.12 part, N of potassium peroxydisulfate, N- dimethyl
0.7 part of acrylamide, 8 parts of gelatin, 5 parts of cyclodextrin, 85 parts of water.
The ingredient of second bactericidal composition includes：
20 parts of 20% sodium silicate solution, 25 parts of 10% sodium bicarbonate solution, 0.8 part of nano-silver powder, nanometer titanium dioxide
2 parts of titanium, 3 parts of 45% dilute sulfuric acid are saturated 9 parts of sodium nitrate.
The ingredient of organic solution includes：
8 parts of polylactic acid, 7 parts of polycaprolactone, 7 parts, N of Poly(D,L-lactide-co-glycolide, 19 parts of N- dimethylpropionamides,
40 parts of acetone.
Wherein, amino-oligosacchride substance includes：Gentamicin.
The preparation of bacteria inhibiting composition in the present embodiment includes the following steps：
(1) according to mass fraction, in an aseptic environment, gelatin and cyclodextrin are dissolved in water at room temperature, then will
N-isopropyl acrylamide, potassium peroxydisulfate, N,N-DMAA are added in solution, mixed solution heating water bath to 70
DEG C, and be slowly stirred with the rotating speed of 100r/min, gradually by decamethylene biguanides dihydrochloride, ethylenediamine two during stirring
The big acetic acid ferrisodium of salicyl, amino-oligosacchride substance, lavo-ofloxacin and Tinidazole are added in solution, persistently stir 3h,
Colloidal substance is obtained, by colloidal substance centrifuge washing, obtains required first bactericidal composition.
(2) according to mass fraction, in an aseptic environment, sodium silicate solution is heated to 85 DEG C under water bath, dropwise
Sodium bicarbonate solution is added, and is slowly stirred with the rotating speed of 130r/min, reacts 20min, then adjusts solution with dilute sulfuric acid
PH value is 6, and nano-silver powder and nano-titanium dioxide are dissolved in the solution, and saturation nitrate solution reaction is added dropwise into solution
Jello is made afterwards, by the object centrifuge washing that is gelled, had both obtained required second bactericidal composition.
(3) according to mass fraction, in an aseptic environment, by N, N- dimethylpropionamides and acetone are uniformly mixing to obtain miscible
Then polylactic acid, polycaprolactone and Poly(D,L-lactide-co-glycolide are added in the mixed solvent, are stirred at room temperature by agent
60min obtains required organic solution.
(4) according to 3:1:The first bactericidal composition, the second bactericidal composition are added in an aseptic environment for 8 mass ratio
It into organic solution, is handled with the rotating speed high speed dispersion of 950r/min, obtains institute required to the processing of hearing aid surface long-acting bacteriostatic
Composition.
Bacteria inhibiting composition provided in this embodiment is used for the antibacterial processing method in hearing aid surface：It is coated with high-pressure electrostatic
Mode composition is coated uniformly on the surface that hearing aid enters ear material, hearing aid then entered ear material be sent to vacuum to do
In dry case, 25h is dried with 30 DEG C of thermostatic, obtains required long-acting bacteriostatic treated hearing aid.
Embodiment 3
A kind of composition for the processing of hearing aid surface long-acting bacteriostatic, it is characterised in that；The composition at subpackage
Include the first bactericidal composition, the second bactericidal composition and organic solution；
According to mass fraction, the ingredient of the first bactericidal composition includes：
4.5 parts of decamethylene biguanides dihydrochloride, 0.9 part of the big acetic acid ferrisodium of two salicyl of ethylenediamine, amino-oligosacchride class
8 parts of substance, 7 parts of lavo-ofloxacin, 5 parts of Tinidazole, 4 parts of n-isopropyl acrylamide, 0.11 part, N of potassium peroxydisulfate, N- dimethyl
0.6 part of acrylamide, 7 parts of gelatin, 4 parts of cyclodextrin, 78 parts of water.
The ingredient of second bactericidal composition includes：
18 parts of 20% sodium silicate solution, 23 parts of 10% sodium bicarbonate solution, 0.7 part of nano-silver powder, nanometer titanium dioxide
1.8 parts of titanium, 2 parts of 45% dilute sulfuric acid are saturated 8 parts of sodium nitrate.
The ingredient of organic solution includes：
6 parts of polylactic acid, 5 parts of polycaprolactone, 6 parts, N of Poly(D,L-lactide-co-glycolide, 17 parts of N- dimethylpropionamides,
35 parts of acetone.
Wherein, amino-oligosacchride substance includes：The mixture of streptomysin, gentamicin and neomycin.
The preparation of bacteria inhibiting composition in the present embodiment includes the following steps：
(1) according to mass fraction, in an aseptic environment, gelatin and cyclodextrin are dissolved in water at room temperature, then will
N-isopropyl acrylamide, potassium peroxydisulfate, N,N-DMAA are added in solution, mixed solution heating water bath to 68
DEG C, and be slowly stirred with the rotating speed of 95r/min, gradually by decamethylene biguanides dihydrochloride, ethylenediamine two during stirring
The big acetic acid ferrisodium of salicyl, amino-oligosacchride substance, lavo-ofloxacin and Tinidazole are added in solution, lasting to stir
2.8h obtains colloidal substance, by colloidal substance centrifuge washing, obtains required first bactericidal composition.
(2) according to mass fraction, in an aseptic environment, sodium silicate solution is heated to 80 DEG C under water bath, dropwise
Sodium bicarbonate solution is added, and is slowly stirred with the rotating speed of 110r/min, reacts 17min, then adjusts solution with dilute sulfuric acid
PH value is 5.5, and nano-silver powder and nano-titanium dioxide are dissolved in the solution, and dropwise addition saturation nitrate solution is anti-into solution
Jello should be made afterwards, by the object centrifuge washing that is gelled, both obtained required second bactericidal composition.
(3) according to mass fraction, in an aseptic environment, by N, N- dimethylpropionamides and acetone are uniformly mixing to obtain miscible
Then polylactic acid, polycaprolactone and Poly(D,L-lactide-co-glycolide are added in the mixed solvent, are stirred at room temperature by agent
50min obtains required organic solution.
(4) according to 3:1:The first bactericidal composition, the second bactericidal composition are added in an aseptic environment for 8 mass ratio
It into organic solution, is handled with the rotating speed high speed dispersion of 850r/min, obtains institute required to the processing of hearing aid surface long-acting bacteriostatic
Composition.
Bacteria inhibiting composition provided in this embodiment is used for the antibacterial processing method in hearing aid surface：It is coated with high-pressure electrostatic
Mode composition is coated uniformly on the surface that hearing aid enters ear material, hearing aid then entered ear material be sent to vacuum to do
In dry case, 22h is dried with 28 DEG C of thermostatic, obtains required long-acting bacteriostatic treated hearing aid.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, although with reference to aforementioned reality
Applying example, invention is explained in detail, for those skilled in the art, still can be to aforementioned each implementation
Technical solution recorded in example is modified or equivalent replacement of some of the technical features.All essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention god.
Claims (7)
1. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic, which is characterized in that the ingredient of the composition includes
First bactericidal composition, the second bactericidal composition and organic solution；
Wherein, according to mass fraction, the ingredient of the first bactericidal composition includes：
4-5 parts of decamethylene biguanides dihydrochloride, 0.4-1.5 parts of two salicyl of ethylenediamine big acetic acid ferrisodium, amino-oligosacchride class
7-10 parts of substance, 5-10 parts of lavo-ofloxacin, 3-6 parts of Tinidazole, 3-5 parts of n-isopropyl acrylamide, potassium peroxydisulfate 0.1-
0.12 part, 0.4-0.7 parts of N,N-DMAA, 6-8 parts of gelatin, 3-5 parts of cyclodextrin, 70-85 parts of water；
The ingredient of second bactericidal composition includes：
15-20 parts of 20% sodium silicate solution, 20-25 parts of 10% sodium bicarbonate solution, 0.5-0.8 parts of nano-silver powder, nanometer two
1.5-2 parts of titanium oxide, 1-3 parts of 45% dilute sulfuric acid are saturated 7-9 parts of sodium nitrate；
The ingredient of organic solution includes：
4-8 parts of polylactic acid, 4-7 parts of polycaprolactone, 5-7 parts, N of Poly(D,L-lactide-co-glycolide, N- dimethylpropionamides 15-
19 parts, 30-40 parts of acetone.
2. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic according to claim 1, it is characterised in that：It presses
According to mass fraction, the ingredient of first bactericidal composition includes：4.2-4.4 parts of decamethylene biguanides dihydrochloride, ethylenediamine
0.8-1.1 parts of two salicyls big acetic acid ferrisodium, 8-9 parts of amino-oligosacchride substance, 6-7 parts of lavo-ofloxacin, Tinidazole 4-5
Part, 3-4 parts of n-isopropyl acrylamide, 0.11-0.12 parts of potassium peroxydisulfate, 0.5-0.6 parts of N,N-DMAA are bright
7-8 parts of glue, 3-4 parts of cyclodextrin, 80-82 parts of water.
3. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic according to claim 1, it is characterised in that：It presses
According to mass fraction, the ingredient of second bactericidal composition includes：17-18 parts of 20% sodium silicate solution, 10% sodium bicarbonate
22-23 parts of solution, 0.6-0.7 parts of nano-silver powder, 1.7-1.8 parts of nano-titanium dioxide, 2.4-2.6 parts of 45% dilute sulfuric acid, saturation
8-9 parts of sodium nitrate.
4. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic according to claim 1, it is characterised in that：It presses
According to mass fraction, the ingredient of the organic solution includes：6-7 parts of polylactic acid, 5-6 parts of polycaprolactone, poly lactic-co-glycolic acid is total
5-6 parts, N of polymers, 17-18 parts of N- dimethylpropionamides, 35-37 parts of acetone.
5. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic according to claim 1, it is characterised in that：Institute
Stating amino-oligosacchride substance includes：One or more mixtures in streptomysin, gentamicin, neomycin.
6. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic according to claim 1, which is characterized in that institute
The preparation for stating combination includes the following steps：
（1）According to mass fraction, in an aseptic environment, gelatin and cyclodextrin are dissolved in water at room temperature, it is then that N- is different
Propylacrylamide, potassium peroxydisulfate, N,N-DMAA are added in solution, mixed solution heating water bath to 65-70
DEG C, and be slowly stirred with the rotating speed of 90-100r/min, gradually by decamethylene biguanides dihydrochloride, second two during stirring
The big acetic acid ferrisodium of two salicyl of amine, amino-oligosacchride substance, lavo-ofloxacin and Tinidazole are added in solution, lasting to stir
2.5-3h obtains colloidal substance, by colloidal substance centrifuge washing, obtains required first bactericidal composition；
（2）According to mass fraction, in an aseptic environment, sodium silicate solution is heated to 75-85 DEG C under water bath, added dropwise
Enter sodium bicarbonate solution, and be slowly stirred with the rotating speed of 100-130r/min, react 15-20min, is then adjusted with dilute sulfuric acid molten
The pH value of liquid is 5-6, and nano-silver powder and nano-titanium dioxide are dissolved in the solution, and dropwise addition saturation nitrate is molten into solution
Jello is made after liquid reaction, by the object centrifuge washing that is gelled, had both obtained required second bactericidal composition；
（3）According to mass fraction, in an aseptic environment, by N, N- dimethylpropionamides and acetone are uniformly mixing to obtain miscible agent,
Then polylactic acid, polycaprolactone and Poly(D,L-lactide-co-glycolide are added in the mixed solvent, 40- is stirred at room temperature
60min obtains required organic solution；
（4）According to 3:1:First bactericidal composition, the second bactericidal composition have been added to by 8 mass ratio in an aseptic environment
It in machine solution, is handled with the rotating speed high speed dispersion of 800-950r/min, obtains institute required to the processing of hearing aid surface long-acting bacteriostatic
Composition.
7. a kind of composition for the processing of hearing aid surface long-acting bacteriostatic according to claim 1, which is characterized in that institute
Stating the composition processing method antibacterial for hearing aid surface is：Composition is coated uniformly in such a way that high-pressure electrostatic is coated with
Hearing aid enters the surface of ear material, and hearing aid, which is then entered ear material, is sent in vacuum drying chamber, permanent with 25-30 DEG C of temperature
The dry 20-25h of temperature obtains required long-acting bacteriostatic treated hearing aid.
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Cited By (1)
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| CN111632334A (en) * | 2020-06-17 | 2020-09-08 | 成都市图腾环保科技有限公司 | Disinfectant, and preparation method and application thereof |
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Application publication date: 20181016 |