CN108630315A - The method of the risk score of eye disease for determining user and system for executing such method - Google Patents
The method of the risk score of eye disease for determining user and system for executing such method Download PDFInfo
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- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/02—Subjective types, i.e. testing apparatus requiring the active assistance of the patient
- A61B3/06—Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing light sensitivity, e.g. adaptation; for testing colour vision
- A61B3/063—Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing light sensitivity, e.g. adaptation; for testing colour vision for testing light sensitivity, i.e. adaptation
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/02—Subjective types, i.e. testing apparatus requiring the active assistance of the patient
- A61B3/06—Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing light sensitivity, e.g. adaptation; for testing colour vision
- A61B3/066—Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing light sensitivity, e.g. adaptation; for testing colour vision for testing colour vision
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- A—HUMAN NECESSITIES
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- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/11—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils
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- A61B2576/00—Medical imaging apparatus involving image processing or analysis
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Abstract
The present invention relates to it is a kind of by computer installation implement for determine user eye disease risk score method, the method includes：First eye adjusts physiological parameter and provides step (S10), in the step process, it provides and indicates that the first eye of the user adjusts consciousness or the first eye of behavior adjusts physiological parameter, second eyes adjust physiological parameter and provide step (S20), in the step process, it provides and indicates that the second eyes of the user adjust consciousness or the second eyes of behavior adjust physiological parameter, and risk score determines step (S30), in the step process, physiological parameter and second eyes adjusting physiological parameter are adjusted based on the first eye to determine the risk score of eye disease.
Description
Technical field
The present invention relates to a kind of methods of the risk score for the eye disease for determining user implemented by computer installation.
The invention further relates to it is a kind of for be determined user eye disease risk score method system, with
And it a kind of is adapted to be performed in the system and wherein eye disease for being determined user in installation
The program of the method for risk score.
Background technology
Some eye disease, such as age-related macular degeneration (" AMD ") lead to the irreversible blindness of people with eye disease.
For example, AMD is usually late diagnosed.Most of people with AMD do not know them with AMD until him
Be diagnosed as late period.In addition, most of people with AMD are irreversible when diagnosing first time and significantly blind quick
Acutance.It, can be with usage behavior correction, nutritional supplementation, light protection, anti-vascular endothelial growth factor (" VEGF ") for diagnostic personnel
It treats to reduce the incidence for proceeding to irreversible visual deprivation.
Since some eye disease rapidly develop, it is therefore desirable to detect these eye disease early.Detecting eye disease early can be
And early treatment provides chance, and provide better possibility for visual outcome.
With the most common approach for diagnosing AMD it is visual acuity for assessing retinal function.However, acuity test letter
It is single and quick, do not have to provide the information about early stage AMD retinal function, because visual acuity caused by early stage AMD changes
It cannot be detected.
Therefore, early stage eye disease, such as AMD can not be detected in daily life and conventional eye test.
Therefore, it is necessary to it is a kind of for determine early stage eye disease, more accurately be used to assess the functional variation of early stage eye disease with
The method for more preferably monitoring its progress.
It is an object of the present invention to provide such methods.
Invention content
For this purpose, the present invention proposes a kind of risk score for the eye disease for determining user implemented by computer installation
Method, the method includes：
First eye adjusts physiological parameter and provides step, in the step process, provides the of the instruction user
One eyes adjust consciousness or the first eye of behavior adjusts physiological parameter,
- the second eyes adjust physiological parameter and provide step, in the step process, provide the of the instruction user
Two eyes adjust consciousness or the second eyes of behavior adjust physiological parameter, and
Risk score determines step, and in the step process, physiological parameter and described is adjusted based on the first eye
Second eyes adjust physiological parameter to determine the risk score of eye disease.
Advantageously, the method for the present invention allows the early stage risk score for calculating eye disease based on multiple parameters.It is more accurate
Ground, method of the invention allow to detect the first functional signal of early stage eye disease based on different parameters to establish correlation and can
Newer risk score.
According to embodiment, the method according to the present invention for providing one group of data may further include below according to appoint
It is one or several in the feature what may be combined：
The first eye adjusting physiological parameter is related to the dark adaptation of at least one eye eyeball of the user, and
Wherein, second eyes adjust pupillary light reflex and/or the institute of physiological parameter and at least one eye eyeball of the user
The flash of light susceptibility for stating at least one eye eyeball of user is related；And/or
By at least one test selected in following test inventory physiology is adjusted in the first eye to determine
Parameter provides the first eye provided in step process and adjusts physiological parameter, and/or adjust physiology in second eyes
Parameter provides second eyes provided in step process and adjusts physiological parameter, and the test inventory is made up of：
The determination of transient state pupillary reaction；
Shrink preclinical determination；
The determination of shrinkage amplitude；
The determination of state after illumination；
The determination of pupil diameter after light shift；
The determination of interim pupillary reaction；
The determination that rod cell about dark adaptation restores；
The determination that cone cell about dark adaptation restores；
The determination of flashlight detection threshold value；And/or
The method further includes：Third eyes adjust physiological parameter offer step and are carried in the step process
For indicating that the third eyes of the user adjust consciousness or the third eyes adjusting physiological parameter of behavior, wherein described in consideration
Third eyes adjust physiological parameter to determine the risk score of eye disease；And/or
The third eyes adjust physiological parameter to it is following related：The photaesthesia of at least one eye eyeball of the user
At least one eye eyeball of the color sensitivity, and/or the user of degree, and/or at least one eye eyeball of the user
The dazzle recovery of contrast sensitivity, and/or at least one eye eyeball of the user, and/or at least the one of the user
The visual acuity of the shape distortion susceptibility of eyes, and/or at least one eye eyeball of the user, and/or described make
The macular pigment of the space contrast degree susceptibility of at least one eye eyeball of user, and/or at least one eye eyeball of the user
Density；And/or
By at least one test selected from following test inventory physiology ginseng is adjusted in the third eyes to determine
Number provides the third eyes provided in step process and adjusts physiological parameter, and the test inventory is made up of：
The determination of visual acuity；
The determination of lightsensitivity threshold value；
The determination of cone cell contrast threshold；
Determination about the cone cell recovery that dazzle restores；And/or
The method further includes：Life overview (life profile) data providing step, in the step process
In, provide the life profile data of at least one parameter of the life overview about user, wherein consider the life overview
Data determine the risk score of eye disease；And/or
The life profile parameters of the user to it is following related：The age of the user, and/or described make
The personal situation of the professional background, and/or the user of the gender of user, and/or the user, and/or the use
The health history of the ordinary circumstance, and/or the user of the life area of person, and/or the user, and/or the use
Family's health history of person, and/or the body movement of the eating habit of the user, and/or the user custom, and/or
The rhythm of life of the user；And/or
The method further includes：Environmental parameter provides step, is provided in the step process and indicates the use
The environmental parameter of the environment of person, wherein consider the environmental parameter to determine the risk score of eye disease；And/or
The light that light exposure, and/or the user of the environmental parameter of the user with the user receive
Radiation and/or spectral emissions and/or spatial distribution and/or exposure history are related；And/or
The method further includes：Eye imaging parameter provides step, in the step process, provides instruction institute
State the eye imaging parameter of the eye imaging of at least one eye eyeball of user, wherein it is true to consider that the eye imaging parameter is come
Determine the risk score of eye disease；And/or
The eye imaging parameter is at least related to the feature of glass-film wart of the eyes of wearer, and the feature includes
At least one of the position of the size and shape of glass-film wart, the gross area of glass-film wart and glass-film wart；And/or
The method further includes：Step is updated, in the step process, the first eye is updated and adjusts life
Manage that parameter, and/or second eyes adjust physiological parameter, and/or the third eyes adjust physiological parameter, and/or described
Profile data of living, and/or the environmental data, and/or the eye imaging parameter, wherein consider the updated number
According to determining the risk score of eye disease.
Advantageously, the method for the present invention allows the early stage risk score for updating eye disease based on multiple parameters.In other words,
The method of the present invention allows to provide accurate and updated risk score value to user.
Advantageously, the method for the present invention allow to help user recognize influence of the different parameters to its risk score,
And user is allowed to change its custom or reinforce some behaviors or custom on the contrary.
The invention further relates to a kind of for executing the risk for determining the eye disease of user point according to the present invention
The system of several methods.
The invention further relates to a kind of program, described program be adapted to be mounted in a system of the invention and
It is wherein performed for executing the method according to the present invention for determining the risk score of the eye disease of user.
The invention further relates to a kind of system for determining the risk score of the eye disease of user, the system packets
It includes：
First eye adjusts physiological parameter and provides device, indicates that the first eye adjusting of the user is known for providing
Feel or the first eye of behavior adjust physiological parameter,
- the second eyes adjust physiological parameter and provide device, indicate that the second eyes adjusting of the user is known for providing
Feel or the second eyes of behavior adjust physiological parameter, and
Risk score determining device, for adjusting physiological parameter and second eyes adjusting based on the first eye
Physiological parameter determines the risk score of eye disease.
The invention further relates to a kind of computer program product, the computer program product is deposited including one or more
The instruction sequence of storage, described instruction are that processor is addressable and cause the processor when being executed by the processor
The step of implementing according to the method for the present invention.
The invention further relates to it is a kind of for determine user eye disease risk score system, the system comprises
Processor, the processor are adapted to store one or more instruction sequences and the step of implementation according to the method for the present invention
At least one of rapid step.
The invention further relates to the computer readable storage mediums that a kind of above-noted has program；Wherein, described program
Computer is set to execute steps of a method in accordance with the invention.
Description of the drawings
Other features and advantages of the present invention will be not limited to provide with reference to attached drawing from claim and below by way of example
Some embodiments description in become apparent：
- Fig. 1 is the stream according to the present invention for determining the different step of the method for the risk score of the eye disease of user
Cheng Tu.
Specific implementation mode
The present invention relates to a kind of risk scores for the eye disease for determining user for example implemented by computer installation
Method.
For example, the method allows the risk score for determining age-related macular degeneration.
Fig. 1 illustrates according to the present invention for determining the different step of the method for the risk score of the eye disease of user
Flow chart.
Physiological parameter offer step (S10) is adjusted the method includes first eye and the second eyes adjust physiological parameter and carry
For step (S20).
During first eye adjusts physiological parameter and provides step (S10), the first eye tune of instruction user is provided
The first eye for saving consciousness or behavior adjusts physiological parameter.
First eye adjusts physiological parameter may be related to the dark adaptation of at least one eye eyeball of user.
During the second eyes adjust physiological parameter and provide step (S20), the second eyes tune of instruction user is provided
The second eyes for saving consciousness or behavior adjust physiological parameter.
Second eyes adjust physiological parameter may with the pupillary light reflex of at least one eye eyeball of user, and/or make
The flash of light susceptibility of at least one eye eyeball of user is related.
It can be carried by least one test to determine to adjust during physiological parameter provides step (S10) in first eye
The first eye of confession adjusts physiological parameter.It is also possible to adjust physiology ginseng in the second eyes by least one test to determine
Number provides the second eyes provided during step (S20) and adjusts physiological parameter.
For determining that the test of the first and/or second eyes adjusting physiological parameter can select in following test inventory,
The test inventory is made of the following terms：The determination of transient state pupillary reaction；Shrink preclinical determination；Shrinkage amplitude is really
It is fixed；The determination of state after illumination；The determination of pupil diameter after light shift；The determination of interim pupillary reaction；About dark adaptation
Rod cell restore determination；The determination that cone cell about dark adaptation restores；The determination of flashlight detection threshold value.
The measurement that the rod cell about dark adaptation restores or the cone cell about dark adaptation restores can be used true
Determine dark adaptation.This test is repeatable and has good diagnosis capability.
The test of the dark adaptation of at least one eye eyeball for determining user can carry out under low light level.
It can use about for example in the excitation of the sinusoidal light of about 480nm (i.e. in inherently photosensitive retinal ganglial cells
Under the high excitation of (" ipRGC ")) and in the sinusoidal light excitation of about 630nm or about sinusoidal light stimulation (such as 11.9 seconds sines
Stimulation) pupil record and determine pupillary light reflex.Pupillary light reflex can be determined before illumination and after illumination.It can
To determine pupillary light reflex during different stimulus durations.Can be used below and higher than blackout element threshold value multifocal pupil
Hole is traced or irradiation level determines pupillary light reflex, with detect rod cell function and cone cell function defect and
The defect of ipRGC functions.This test is quick, objective, Noninvasive and repeatable.
Flash of light susceptibility can be determined using flash stimulation.This test quickly (for example, about 4 to 7 minutes), can weigh
Again, it is clinically applicable in and there is good diagnosis capability.
It can be static parameter or dynamic parameter that first and second eyes, which adjust physiological parameter,.In addition, first and second
One in eyeball adjusting physiological parameter can be static parameter, and the first and second eyes adjust another in physiology ginseng
It can be dynamic parameter.
The method includes：Risk score determines step (S30), in the step process, is adjusted based on first eye
Physiological parameter and the second eyes adjust physiological parameter to determine the risk score of eye disease.
Advantageously, determining that the risk score of eye disease allows the detection early for improving eye disease based on multiple parameters.
The risk score of eye disease can be determined based on the combination of static parameter and dynamic parameter.
The method may include：Third eyes adjust physiological parameter and provide step (S22), in the step process,
The third eyes for providing instruction user adjust consciousness or the third eyes of behavior adjust physiological parameter.
Third eyes adjust physiological parameter may to it is following related：The lightsensitivity of at least one eye eyeball of user and/
Or at least one eye eyeball of the color sensitivity, and/or user of at least one eye eyeball of user contrast sensitivity,
And/or the oxyopia of at least one eye eyeball of the shape distortion susceptibility, and/or user of at least one eye eyeball of user
The Huang of at least one eye eyeball of the space contrast degree susceptibility, and/or user of degree, and/or at least one eye eyeball of user
Spot pigment density.
Third eyes adjust physiological parameter may be at least one eye eyeball of user dazzle recovery, and/or user
At least one eye eyeball photostress restore.
Third eyes adjust physiological parameter may to it is following related：The color function of at least one eye eyeball of user and/
Or the low contrast oxyopia of at least one eye eyeball of the visual distortion, and/or user of at least one eye eyeball of user
Degree.
It can be carried by least one test to determine to adjust during physiological parameter provides step (S22) in third eyes
The third eyes of confession adjust physiological parameter.
It can be selected in the test inventory being made of the following terms for determining that three eyes adjust testing for physiological parameter：Depending on
Feel the determination of acuity；The determination of lightsensitivity threshold value；The determination of cone cell contrast threshold；The cone restored about dazzle
The determination that cell restores.
For determining that the test inventory of third eyes adjusting physiological parameter may include the determination of color sensitivity threshold value.This
A test quickly and readily uses.
For determining that test inventory that third eyes adjust physiological parameter may include the determination and/or dizzy of photostress recovery
The determination that light restores.These tests quickly and readily use.
It can be with for example from 50 lux steps of 0 to 1000 lux or from 1000 luxs to 2000 luxs
It 100 lux steps or strangles from 200 lux steps of 2000 luxs to 4000 luxs or from 4000 to 8000
Gram this 400 lux steps, per step 10 seconds during dynamic autoization light sequence determination light sensitivity threshold value.It can be random
Light sensitivity threshold value is determined during fixed lighting level sequence.It can use for gradually activating the portable and uniform of photochromic lens
Lighting ball determines light sensitivity threshold value using ultraviolet light (" UV ") light emitting diode (" LED ").It can use from for example
The natural white light of 4000K determines light sensitivity threshold to the correlated colour temperature (" CCT ") for the perishing white light for being greater than 6500K
Value.This test is easy to implement and is clinically applicable in.
Contrast sensitivity can be determined using cone cell contrast threshold.
It can be tested using Amsler grid (Amsler grid) to determine visual distortion.
It can be static parameter or dynamic parameter that third eyes, which adjust physiological parameter,.
It is contemplated that third eyes adjust physiological parameter to determine the risk score of eye disease.
The method may include：Live profile data provide step (S24), in the step process, provide about
The life profile data of at least one parameter of the life overview of user.
The life profile parameters of user can to it is following related：The age of user, and/or the gender of user and/
Or professional background, and/or the personal situation of user, and/or life area, and/or the user of user of user
The body movement of ordinary circumstance, and/or user are accustomed to.
The life profile parameters of user can be related to the health history of user, for example, it is related to photosensitive treatment or with
The cataract operation of at least one eye eyeball of user is related.
The life profile parameters of user can be related to the race of user.
The life profile parameters of user can be related to family's health history of user, for example, user parent whether
With eye disease, such as AMD.The life profile parameters of user can be with the genetic correlation of user.
The life profile parameters of user can to it is following related：The eating habit of user, and/or the life of user
Rhythm, such as whether user smokes or the diet of user.
The life profile parameters of user can to it is following related：Oxidative stress source (as smoking is handled), antioxidant are few
Diet, light processing or photosensitive processing.
The life profile parameters of user can to it is following related：Safeguard measure used in user, i.e., whether user
Use sunglasses or cap.
The life profile parameters of user can be determined by questionnaire survey.
It is contemplated that living profile parameters to determine the risk score of eye disease.
The method may include：Environmental parameter provides step (S26), and instruction user is provided in the step process
Environment environmental parameter.
The radiation for the light that the environmental parameter of user can be received with the exposure of the light of user, and/or by user and/
Or spectral emissions and/or spatial distribution and/or exposure history it is related.
The radiation of the quantity of light source and/or the spatial distribution and/or light source of the positioning of light source and/or light source can be passed through
The spatial distribution and/or the length of exposure of user of (directionality for including light) and/or light source and/or the exposure of user
The association of number of repetition exposes to limit the light of user.
It includes spectrometer and/or color photoelectric diode (such as UV, blue, green, red and infrared (" IR ") light that can use
Electric diode) connection glasses come determine use light exposure.
The risk score of eye disease can be determined by considering environmental parameter.
The method may include：Eye imaging parameter provides step (S28) and provides instruction in the step process
The eye imaging parameter of the eye imaging of at least one eye eyeball of user.
Eye imaging parameter can be at least related to the feature of glass-film wart of the eyes of wearer.The eyes of wearer
The feature of glass-film wart may include the size and shape of glass-film wart, the gross area of glass-film wart and glass-film wart position
At least one of set.
The feature of the glass-film wart of the eyes of wearer may include the type of glass-film wart, such as big when glass-film wart
It is rigid glass-film wart when being less than 63 μm, is medium soft when the size of glass-film wart is included between 63 μm and 125 μm
Glass-film wart, and be half big solidity glass-film wart when the size of glass-film wart is more than 125 μm.
Eye imaging parameter can be at least the one of the pigment anomaly of at least one eye eyeball of user, and/or user
The choroidal neovascularization of the geographic atrophy of eyes, and/or at least one eye eyeball of user is related.
It is contemplated that eye imaging parameter determines the risk score of eye disease.
Specifically, age related eye diseases research risk (" AREDS ") can be based only upon eye imaging parameter.For example,
AREDS may include the score between 1 and 4.Score 1 correspond to user at least one eye eyeball in there is no glass-film wart,
Or the size of glass-film wart is less than 63 μm, and the gross area of glass-film wart is less than 125 μm.Score 2 corresponds to no map
Shape atrophy, and the size of glass-film wart be greater than or equal to 63 μm and be less than 125 μm, and the gross area of glass-film wart be more than or
Equal to 125 μm.Score 3a corresponds to soft apparent glass-film wart, and the size of glass-film wart is more than or equal to 63 μm and small
In 125 μm, and the gross area of glass-film wart is more than 360 μm.Score 3b corresponds to soft fuzzy glass-film wart, and glass
The size of film wart is greater than or equal to 63 μm and is less than 125 μm, and the gross area of glass-film wart is more than 656 μm.Score 4 is accordingly
The atrophy of figure shape or choroidal neovascularization and the visual acuity less than 20/32.
The method may further include update step (S40).
During updating step (S40), update first eye adjusts physiological parameter, and/or the second eyes adjust life
Manage parameter, and/or third eyes adjust physiological parameter, and/or life profile data, and/or environmental data, and/or eyes at
As parameter.
It is contemplated that updated data determine the risk score of eye disease.
Advantageously, the risk score of the eye disease of more new user allows to provide accurate and updated risk to user
Fractional value.More accurately, this update allows that user is helped to recognize influence of the different parameters to its risk score and allows
User changes its custom or reinforces some behaviors or custom on the contrary.
Can according to the activity of user, and/or user, and/or user target to be achieved and performance, and/or
The doctor of user, and/or the position of user carry out personalized first eye and adjust physiological parameter, and/or the adjusting of the second eyes
Physiological parameter, and/or third eyes adjust physiological parameter and/or life profile data, and/or environmental data, and/or eyes at
As parameter.
The invention further relates to a kind of risks for executing the eye disease for determining user as previously described
The system of the method for score.
The system may include sensor or one or more sensors, and physiology ginseng is adjusted for measuring first eye
Number, and/or the second eyes adjust physiological parameter, and/or third eyes adjust physiological parameter and/or environmental data, and/or eyes
Imaging parameters.
After the risk score for the eye disease for determining user, the system can swash according to identified risk score
Specific function living.For example, specific function to be activated can be in home automation or the automation of vehicle or user's medical treatment
The alarm trigger of the heart.
The present invention is described by means of embodiment above, and is not intended to limit present general inventive concept.Moreover, the present invention
Embodiment can be combined to no any restrictions.
For those skilled in the art with reference to embodiments illustrated above, it is also proposed that many other modifications
And variation, these embodiments only provide by way of example, it is not intended to limit the scope of the invention, the scope of the present invention is only by appended power
Profit requires to determine.
In the claims, other element or steps, and indefinite article " one (a) " is not precluded in word " comprising "
Or plural number is not precluded in " one (an) ".It is simple that different features is described this in mutually different dependent claims
The fact is not offered as that the combination of these features cannot be used to advantage.Any reference numeral in claim shall not be solved
It is interpreted as limiting the scope of the invention.
Claims (15)
1. a kind of method of the risk score for the eye disease for determining user implemented by computer installation, the method packet
It includes：
First eye adjusts physiological parameter and provides step (S10), in the step process, provides the instruction user's
First eye adjusts consciousness or the first eye of behavior adjusts physiological parameter,
- the second eyes adjust physiological parameter and provide step (S20), in the step process, provide the instruction user's
Second eyes adjust consciousness or the second eyes of behavior adjust physiological parameter, and
Risk score determines step (S30), and in the step process, physiological parameter and institute are adjusted based on the first eye
It states the second eyes and adjusts physiological parameter to determine the risk score of eye disease.
2. according to the method described in claim 1, wherein, the first eye adjusts physiological parameter and the user at least
The dark adaptation of one eye eyeball is related, and wherein, and second eyes adjust at least one of physiological parameter and the user
The flash of light susceptibility of the pupillary light reflex of eyes and/or at least one eye eyeball of the user is related.
3. method according to claim 1 or 2, wherein pass through at least one survey selected in following test inventory
It tries to determine that adjusting physiological parameter in the first eye provides the first eye provided in step process adjusting physiology ginseng
Number, and/or second eyes provided in second eyes adjusting physiological parameter offer step process adjust physiology ginseng
Number, the test inventory are made up of：
The determination of transient state pupillary reaction；
Shrink preclinical determination；
The determination of shrinkage amplitude；
The determination of state after illumination；
The determination of pupil diameter after light shift；
The determination of interim pupillary reaction；
The determination that rod cell about dark adaptation restores；
The determination that cone cell about dark adaptation restores；
The determination of flashlight detection threshold value.
4. method according to any one of the preceding claims, further comprises：
Third eyes adjust physiological parameter and provide step (S22), in the step process, provide the instruction user's
Third eyes adjust consciousness or the third eyes of behavior adjust physiological parameter,
Wherein, consider that the third eyes adjust physiological parameter to determine the risk score of eye disease.
5. according to the method described in claim 4, wherein, the third eyes adjust physiological parameter to it is following related：It is described to make
The color sensitivity of the lightsensitivity of at least one eye eyeball of user, and/or at least one eye eyeball of the user, and/or
The dazzle of the contrast sensitivity of at least one eye eyeball of the user, and/or at least one eye eyeball of the user is extensive
The shape distortion susceptibility of at least one eye eyeball of the multiple, and/or described user, and/or at least one eye of the user
The space contrast degree susceptibility of at least one eye eyeball of the visual acuity of eyeball, and/or the user, and/or the use
The macular pigment optical density of at least one eye eyeball of person.
6. method according to claim 4 or 5, wherein pass through at least one test selected from following test inventory
The third eyes adjusting physiological parameter provided in physiological parameter offer step process is adjusted in the third eyes to determine,
The test inventory is made up of：
The determination of visual acuity；
The determination of lightsensitivity threshold value；
The determination of cone cell contrast threshold；
Determination about the cone cell recovery that dazzle restores.
7. method according to any one of the preceding claims, further comprises：
Life profile data provides step (S24) and is provided and the life overview of the user in the step process
At least one relevant life profile data of parameter,
Wherein, the life profile data is considered to determine the risk score of eye disease.
8. according to the method described in claim 7, wherein, the life profile parameters of the user to it is following related：Institute
State the age of user, and/or the professional background, and/or the use of the gender of the user, and/or the user
The ordinary circumstance of the personal situation of person, and/or the life area of the user, and/or the user, and/or described make
The eating habit of the family's health history, and/or the user of the health history of user, and/or the user, and/or described
The body movement of user is accustomed to, and/or the rhythm of life of the user.
9. method according to any one of the preceding claims, further comprises：
Environmental parameter provides step (S26), and the environment ginseng for indicating the environment of the user is provided in the step process
Number,
Wherein, the environmental parameter is considered to determine the risk score of eye disease.
10. according to the method described in claim 9, wherein, the light exposure of the environmental parameter of the user and the user,
And/or the radiation of light that receives of the user and/or spectral emissions and/or spatial distribution and/or exposure history it is related.
11. method according to any one of the preceding claims, further comprises：
Eye imaging parameter provides step (S28), in the step process, provides at least one of the instruction user
The eye imaging parameter of the eye imaging of eyes,
Wherein, the eye imaging parameter is considered to determine the risk score of eye disease.
12. according to the method for claim 11, wherein glass of the eye imaging parameter at least with the eyes of wearer
The feature of film wart is related, and the feature includes the size and shape of glass-film wart, the gross area of glass-film wart and glass-film wart
At least one of position.
13. method according to any one of the preceding claims, further comprises：
Step (S40) is updated, in the step process, the first eye is updated and adjusts physiological parameter, and/or described the
Two eyes adjust physiological parameter, and/or the third eyes adjust physiological parameter, and/or the life profile data, and/or
The environmental data, and/or the eye imaging parameter,
Wherein, the updated data are considered to determine the risk score of eye disease.
14. a kind of for executing the risk according to any one of claim 1 to 13 for determining the eye disease of user
The system of the method for score.
15. a kind of program, described program is adapted in the system described in claim 14 that is installed in and at it
In be performed and carry out the risk score according to any one of claim 1 to 13 for determining the eye disease of user
Method.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305330.7A EP3378377B1 (en) | 2017-03-23 | 2017-03-23 | Method for determining a risk score of an eye disease for a user and system for the execution of such method |
| EPEP17305330.7 | 2017-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108630315A true CN108630315A (en) | 2018-10-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810242541.3A Pending CN108630315A (en) | 2017-03-23 | 2018-03-23 | The method of the risk score of eye disease for determining user and system for executing such method |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20180271360A1 (en) |
| EP (1) | EP3378377B1 (en) |
| CN (1) | CN108630315A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3773149B1 (en) * | 2018-06-20 | 2023-11-01 | Alcon Inc. | Auxiliary surgical field visualization system |
| CN110708361B (en) * | 2019-09-18 | 2022-06-03 | 北京奇艺世纪科技有限公司 | System, method and device for determining grade of digital content publishing user and server |
| US20220039653A1 (en) * | 2020-08-10 | 2022-02-10 | Welch Allyn, Inc. | Microvascular assessment using eye imaging device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100302507A1 (en) * | 2009-05-28 | 2010-12-02 | Annidis Health Systems Corp. | Method and system for retinal health management |
| WO2011044791A1 (en) * | 2009-10-13 | 2011-04-21 | 中兴通讯股份有限公司 | Method and access support node for sending interworking service message |
| WO2016099402A1 (en) * | 2014-12-16 | 2016-06-23 | Singapore Health Services Pte Ltd | A method and system for monitoring and/or assessing pupillary responses |
| CN106066938A (en) * | 2016-06-03 | 2016-11-02 | 贡京京 | A kind of disease prevention and health control method and system |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5607640B2 (en) * | 2008-10-15 | 2014-10-15 | オプティブランド リミティド，リミティド ライアビリティ カンパニー | Method and apparatus for obtaining images of eye features |
| WO2014151114A1 (en) * | 2013-03-15 | 2014-09-25 | Vasoptic Medical Inc. | Ophthalmic examination and disease management with multiple illumination modalities |
| US9737205B2 (en) * | 2013-07-31 | 2017-08-22 | The Board Of Trustees Of The Leland Stanford Junior University | Method and system for evaluating progression of age-related macular degeneration |
-
2017
- 2017-03-23 EP EP17305330.7A patent/EP3378377B1/en active Active
-
2018
- 2018-03-22 US US15/928,619 patent/US20180271360A1/en not_active Abandoned
- 2018-03-23 CN CN201810242541.3A patent/CN108630315A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100302507A1 (en) * | 2009-05-28 | 2010-12-02 | Annidis Health Systems Corp. | Method and system for retinal health management |
| WO2011044791A1 (en) * | 2009-10-13 | 2011-04-21 | 中兴通讯股份有限公司 | Method and access support node for sending interworking service message |
| WO2016099402A1 (en) * | 2014-12-16 | 2016-06-23 | Singapore Health Services Pte Ltd | A method and system for monitoring and/or assessing pupillary responses |
| CN106066938A (en) * | 2016-06-03 | 2016-11-02 | 贡京京 | A kind of disease prevention and health control method and system |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3378377B1 (en) | 2021-07-07 |
| EP3378377A1 (en) | 2018-09-26 |
| US20180271360A1 (en) | 2018-09-27 |
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