CN108619171A - A kind of preparation method of the electromagnetic shielding medical gel material containing egg oil/liposome - Google Patents
A kind of preparation method of the electromagnetic shielding medical gel material containing egg oil/liposome Download PDFInfo
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Abstract
The present invention provides a kind of preparation method of the electromagnetic shielding medical gel material containing egg oil/liposome, includes the following steps：After cooked yolk is crushed drying, it is added to the water uniformly mixed, addition protease hydrolytic, centrifugation after being extracted with ethyl alcohol, removes ethyl alcohol, the egg oil purified；Polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol are added to the water, after being sufficiently stirred dissolving, heating continues to stir, and is cooled to room temperature addition initiator, ultraviolet curing obtains acrylic hydrogel；It after acrylic hydrogel vacuum freezedrying, takes out, egg oil and metal salt solution is added at room temperature, be slowly stirred to acrylic hydrogel and restore to obtain the acrylic gel of the loading metal-salt containing egg oil fully after absorption to room temperature；It by the acrylic gel containing egg oil after maturation process, is slowly added into liposome, stirs evenly, swelling overnight, obtains the electromagnetic shielding medical gel material containing egg oil/liposome.
Description
Technical field
The invention belongs to medical material tech fields, and in particular to a kind of electromagnetic shielding containing egg oil/liposome is medical
The preparation method of gel rubber material.
Background technology
With the development of science and technology, the utilization of ray is also more and more extensive, especially in terms of medicine, radiation is in medical treatment and diagnosis
Aspect all has a decisive role, and has good therapeutic effect in treatment breast cancer, uterine cancer, cancer of the esophagus, lung cancer etc.,
But ionising radiation is applied while having brought huge interests, side effect is also big, such as dizzy, weak, nauseous,
Even carcinogenic etc. symptoms of vomiting, therefore it is to develop the important mesh of radiation proof material to reduce the harm caused by people to greatest extent
's.
Gel, which is a kind of semi-solid state, has viscoelastic dispersion, in its system, high-polymer molecular or glue
Body particle forms space three-dimensional reticular structure by the interaction of hydrophobic force, electrostatic force, hydrogen bond or pi bond, and gel is made to be in
A kind of semi-solid state between solid and liquid.According to the difference of decentralized medium, aeroge, hydrogel and organic solidifying can be divided into
The features such as glue, wherein hydrogel are because of water content height, good mechanical property, superior biocompatibility, has in medical field and widely answers
With.
A kind of ferromagnetic conductive aerogel material disclosed in Chinese patent CN 105271184B and preparation method thereof, will be extra large
The natural anionic polysaccharide polymers solution of mosanom/low-ester pectin and nickel nitrate/cobalt nitrate metal salt solution stir to form water-setting
After hydrogel is once then carried out washing by soaking with deionized water, ethanol water, it is solidifying to immerse formation ethyl alcohol in ethyl alcohol for glue
Then ethyl alcohol gel progress supercritical drying is obtained aeroge, then aeroge is placed in inert gas first in 150- by glue
After being kept the temperature at 200 DEG C, it is warming up to 300-500 DEG C of heat preservation, 800-1100 DEG C of high temperature carbonization is finally warming up to and handles to obtain ferromagnetism
Conductive aeroge, the ferromagnetic conductive aeroge are the charcoal-aero gel containing metal nanoparticle, the ferromagnetic conductive airsetting glue material
Material has high conductivity and higher magnetic conductivity, is ideal electromagnetic shielding material.(" medical radiation-ray preventive sprays Chinese document
Application of the egg oil in radiotherapy in breast cancer is combined in agent ", remaining dawn is chivalrous etc., Shaanxi medical journal, page 1101, the 8th phase of volume 45,
In August, 2016) main component that superoxide dismutase SOD is radioactive protection spray is disclosed, it is free that internal oxygen can be removed
Base improves body free radical ability, reduces side effect of the radiotherapy to human body, shortens the skin healing time, egg oil is used
The vigor of superoxide dismutase SOD or more can be improved in superoxide dismutase SOD radioactive protection sprays jumps injury tissue
Interior anti-peroxidation ability.Wherein, egg oil, also referred to as egg-yolk lipids are the fresh ovum of chicken through yolk obtained from separation and Extraction
The main component of extract, egg oil includes a variety of medicines such as lecithin, aliphatic acid, cholesterine, folic acid, carrotene, calcium, phosphorus, iron
With and nutritional ingredient, there is clearing heat, releasing toxin, removing swelling, the effect of nourishing yin and nourishing blood is moisturized, expelling pus and promoting granulation is put on flesh.The master of egg oil at present
It is yolk and yolk powder to extract raw material, is prepared into through cracking process, oven drying method, the extraction of chloroform organic solvent or supercritical extract
To egg oil, but there is no the reports combined egg oil with gel rubber material for Medical electromagnetic shielding material in the prior art.
Invention content
The technical problem to be solved in the present invention is to provide a kind of electromagnetic shielding medical gel material containing egg oil/liposome
Preparation method, after the acrylic hydrogel vacuum freeze drying of ultraviolet curing, fully adsorb egg oil and metal salt it is molten
Liquid, last surface Coated Liposomes, the electromagnetic shielding medical gel material containing egg oil/liposome being prepared, the present invention
The electromagnetic shielding medical gel material containing egg oil/liposome prepared can be coated on skin surface, protect excessive electricity for a long time
Infringement of the magnetic radiation to human body reduces side effect.
In order to solve the above technical problems, the technical scheme is that：
A kind of preparation method of the electromagnetic shielding medical gel material containing egg oil/liposome, includes the following steps：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, protease hydrolytic be added, ethyl alcohol is used in centrifugation
After extraction, ethyl alcohol, the egg oil purified are removed；
(2) polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol are added to the water, are sufficiently stirred molten
Xie Hou is warming up to 90-100 DEG C and continues to stir 30min, is then cooled to room temperature addition initiator, through ultraviolet curing, obtains third
Olefin(e) acid hydrogel；
(3) after freezing acrylic hydrogel prepared by step (2) at -20~-30 DEG C, vacuum drying obtains drying
Acrylic hydrogel；
(4) acrylic hydrogel for the drying for preparing step (3) takes out, and egg prepared by step (1) is added at room temperature
Butter and metal salt solution are slowly stirred to acrylic hydrogel and restore to room temperature, fully after absorption, obtain negative containing egg oil
Carry the acrylic gel of metal salt；
(5) acrylic gel containing egg oil for preparing step (4) is slowly added into liposome after maturation process
In, it stirs evenly, is swollen overnight under 4 DEG C of environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome.
As a preferred embodiment of the above technical solution, in the step (1), the temperature of hydrolysis is 4-8 DEG C, time 30-
90min。
As a preferred embodiment of the above technical solution, in the step (2), polyethyleneglycol diacrylate, polyethylene glycol and poly-
The mass ratio of vinyl pyrrolidine alcohol is 8-10:12-20：16-18.
As a preferred embodiment of the above technical solution, in the step (2), initiator Irgacure2959, content 0.5-
1%.
As a preferred embodiment of the above technical solution, in the step (2), the condition of ultraviolet curing is, first in 10-15 power
After lower solidification 10-15s, cure 30-45s under 30-50W power.
As a preferred embodiment of the above technical solution, in the step (2), the degree of cross linking of acrylic hydrogel is 25-28%.
As a preferred embodiment of the above technical solution, in the step (3), the vacuum drying time is 0.5-2d.
As a preferred embodiment of the above technical solution, in the step (4), the volume ratio of egg oil and metal salt solution is 1:
0.3-0.5, metal salt solution are that mass ratio is 8-10:1 plumbi nitras and the mixed solution of lanthanum nitrate.
As a preferred embodiment of the above technical solution, in the step (4), the acrylic gel of the loading metal-salt containing egg oil
The content of the loading metal-salt of mesolecithal oil is not less than 15%.
As a preferred embodiment of the above technical solution, in the step (5), the electromagnetic shielding containing egg oil/liposome is medical solidifying
The content of liposome is 12-18% in glue material.
Compared with prior art, the invention has the advantages that：
(1) preparation method of the electromagnetic shielding medical gel material containing egg oil/liposome of the invention, is with poly- second two
Raw material is wanted based on alcohol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol, through ultraviolet radiation crosslinking Treatment, is prepared
Degree of cross linking height and the high hydrogel of biological safety, then using the acrylic hydrogel as main carriers, by acrylic hydrogel
After vacuum freeze drying, egg oil and metal salt solution are fully adsorbed, metal nano material, last surface are formed through maturation process
Coated Liposomes, the electromagnetic shielding medical gel material containing egg oil/liposome being prepared.
(2) by egg oil and nanometer in the electromagnetic shielding medical gel material containing egg oil/liposome prepared by the present invention
The particle of metallic lead and rare earth is as major electromagnetic shielding material, and the particle of nano metal lead and rare earth is as the object for absorbing ray
Matter, egg oil can act on the resistance that skin surface is improved with skin surface, and human body is improved after the two is combined to excess radiation
The egodefense ability of amount reduces side effect, and utilizes the superpower absorption of hydrogel and latching effect and the protection of liposome
Effect, Long-Term Protection of the skin surface to human body can be attached to for a long time by improving medical gel material, be protected for a long time
Infringement of the electromagnetic radiation to human body is measured, side effect is reduced.
(3) preparation method of the invention is simple, and controllability is strong, the medical gel material adhesion of preparation, mechanical property,
Water lock and electromagnetic shielding efficiency are all good, are suitable for the shield ranges of various radiation.
Specific implementation mode
Below in conjunction with specific embodiment, the present invention will be described in detail, herein illustrative examples and explanation of the invention
For explaining the present invention, but it is not as a limitation of the invention.
Embodiment 1：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, the mass ratio according to yolk and protease is
1:0.05, protease is added, 30min is hydrolyzed at 4 DEG C, centrifuges, after being extracted with ethyl alcohol, removes ethyl alcohol, the yolk purified
Oil.
(2) it is 8 according to mass ratio:12：16, by polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol
It is added to the water, after being sufficiently stirred dissolving, is warming up to 90 DEG C and continues to stir 30min, be then cooled to room temperature addition and account for total volume
Content be 0.5% initiator Irgacure2959, first under 10W power cure 10s after, cure 30s under 30W power, obtain
The acrylic hydrogel for being 25% to the degree of cross linking.
(3) after freezing acrylic hydrogel at -20 DEG C, it is dried in vacuo 0.5d, obtains dry acrylic hydrogel.
(4) dry acrylic hydrogel is taken out, it is 1 that volume ratio is added at room temperature:0.3 egg oil and metal salt are molten
Liquid, wherein metal salt solution are that mass ratio is 8:1 plumbi nitras and the mixed solution of lanthanum nitrate are first stirred with the rate of 50r/min
After mixing 5min, stirring to acrylic hydrogel is continued with the rotating speed of 200r/min and is restored to room temperature, fully after absorption, obtains containing egg
The acrylic gel of the loading metal-salt of butter, wherein the acrylic gel mesolecithal oil of the loading metal-salt containing egg oil
The content of loading metal-salt is not less than 15%.
(5) acrylic gel containing egg oil is slowly added into after maturation process in liposome, is stirred evenly, 4
It is swollen overnight under DEG C environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome, wherein oil/lipid containing yolk
The content of liposome is 12% in the electromagnetic shielding medical gel material of body.
Embodiment 2：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, the mass ratio according to yolk and protease is
1:0.08, protease is added, 90min is hydrolyzed at 8 DEG C, centrifuges, after being extracted with ethyl alcohol, removes ethyl alcohol, the yolk purified
Oil.
(2) it is 10 according to mass ratio:20：18, by polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol
It is added to the water, after being sufficiently stirred dissolving, is warming up to 100 DEG C and continues to stir 30min, be then cooled to room temperature addition and account for total volume
Content be 1% initiator Irgacure2959, first under 15W power cure 15s after, cure 45s under 50W power, obtain
The acrylic hydrogel that the degree of cross linking is 28%.
(3) after freezing acrylic hydrogel at -30 DEG C, it is dried in vacuo 2d, obtains dry acrylic hydrogel.
(4) dry acrylic hydrogel is taken out, it is 1 that volume ratio is added at room temperature:0.5 egg oil and metal salt are molten
Liquid, wherein metal salt solution are that mass ratio is 10:1 plumbi nitras and the mixed solution of lanthanum nitrate are first stirred with the rate of 80r/min
After mixing 10min, stirring to acrylic hydrogel is continued with the rotating speed of 300r/min and restores to room temperature to be contained fully after absorption
The acrylic gel of the loading metal-salt of egg oil, wherein the acrylic gel mesolecithal oil of the loading metal-salt containing egg oil
Loading metal-salt content be not less than 15%.
(5) acrylic gel containing egg oil is slowly added into after maturation process in liposome, is stirred evenly, 4
It is swollen overnight under DEG C environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome, wherein oil/lipid containing yolk
The content of liposome is 18% in the electromagnetic shielding medical gel material of body.
Embodiment 3：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, the mass ratio according to yolk and protease is
1:0.05, protease is added, 30min is hydrolyzed at 8 DEG C, centrifuges, after being extracted with ethyl alcohol, removes ethyl alcohol, the yolk purified
Oil.
(2) it is 10 according to mass ratio:12：18, by polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol
It is added to the water, after being sufficiently stirred dissolving, is warming up to 90 DEG C and continues to stir 30min, be then cooled to room temperature addition and account for total volume
Content be 1% initiator Irgacure2959, first under 10W power cure 15s after, cure 45s under 30W power, obtain
The acrylic hydrogel that the degree of cross linking is 25%.
(3) after freezing acrylic hydrogel at -30 DEG C, it is dried in vacuo 0.5d, obtains dry acrylic hydrogel.
(4) dry acrylic hydrogel is taken out, it is 1 that volume ratio is added at room temperature:0.5 egg oil and metal salt are molten
Liquid, wherein metal salt solution are that mass ratio is 8:1 plumbi nitras and the mixed solution of lanthanum nitrate are first stirred with the rate of 80r/min
After mixing 5min, stirring to acrylic hydrogel is continued with the rotating speed of 300r/min and is restored to room temperature, fully after absorption, obtains containing egg
The acrylic gel of the loading metal-salt of butter, wherein the acrylic gel mesolecithal oil of the loading metal-salt containing egg oil
The content of loading metal-salt is not less than 15%.
(5) acrylic gel containing egg oil is slowly added into after maturation process in liposome, is stirred evenly, 4
It is swollen overnight under DEG C environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome, wherein oil/lipid containing yolk
The content of liposome is 15% in the electromagnetic shielding medical gel material of body.
Embodiment 4：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, the mass ratio according to yolk and protease is
1:0.08, protease is added, 90min is hydrolyzed at 4 DEG C, centrifuges, after being extracted with ethyl alcohol, removes ethyl alcohol, the yolk purified
Oil.
(2) it is 8 according to mass ratio:20：16, by polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol
It is added to the water, after being sufficiently stirred dissolving, is warming up to 100 DEG C and continues to stir 30min, be then cooled to room temperature addition and account for total volume
Content be 0.5% initiator Irgacure2959, first under 15W power cure 10s after, cure 30s under 50W power, obtain
The acrylic hydrogel for being 26% to the degree of cross linking.
(3) after freezing acrylic hydrogel at -20 DEG C, it is dried in vacuo 2d, obtains dry acrylic hydrogel.
(4) dry acrylic hydrogel is taken out, it is 1 that volume ratio is added at room temperature:0.3 egg oil and metal salt are molten
Liquid, wherein metal salt solution are that mass ratio is 10:1 plumbi nitras and the mixed solution of lanthanum nitrate are first stirred with the rate of 50r/min
After mixing 10min, stirring to acrylic hydrogel is continued with the rotating speed of 200r/min and restores to room temperature to be contained fully after absorption
The acrylic gel of the loading metal-salt of egg oil, wherein the acrylic gel mesolecithal oil of the loading metal-salt containing egg oil
Loading metal-salt content be not less than 15%.
(5) acrylic gel containing egg oil is slowly added into after maturation process in liposome, is stirred evenly, 4
It is swollen overnight under DEG C environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome, wherein oil/lipid containing yolk
The content of liposome is 16% in the electromagnetic shielding medical gel material of body.
Embodiment 5：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, the mass ratio according to yolk and protease is
1:0.06, protease is added, hydrolyzes 60min at 5 DEG C, centrifuges, after being extracted with ethyl alcohol, removes ethyl alcohol, the yolk purified
Oil.
(2) it is 9 according to mass ratio:15：17, by polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol
It is added to the water, after being sufficiently stirred dissolving, is warming up to 95 DEG C and continues to stir 30min, be then cooled to room temperature addition and account for total volume
Content be 0.7% initiator Irgacure2959, first under 13W power cure 13s after, cure 35s under 45W power, obtain
To the acrylic hydrogel that the degree of cross linking is 25-28%.
(3) after freezing acrylic hydrogel at -25 DEG C, it is dried in vacuo 1d, obtains dry acrylic hydrogel.
(4) dry acrylic hydrogel is taken out, it is 1 that volume ratio is added at room temperature:0.4 egg oil and metal salt are molten
Liquid, wherein metal salt solution are that mass ratio is 9:1 plumbi nitras and the mixed solution of lanthanum nitrate are first stirred with the rate of 70r/min
After mixing 6min, stirring to acrylic hydrogel is continued with the rotating speed of 250r/min and is restored to room temperature, fully after absorption, obtains containing egg
The acrylic gel of the loading metal-salt of butter, wherein the acrylic gel mesolecithal oil of the loading metal-salt containing egg oil
The content of loading metal-salt is not less than 15%.
(5) acrylic gel containing egg oil is slowly added into after maturation process in liposome, is stirred evenly, 4
It is swollen overnight under DEG C environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome, wherein oil/lipid containing yolk
The content of liposome is 15% in the electromagnetic shielding medical gel material of body.
Embodiment 6：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, the mass ratio according to yolk and protease is
1:0.07, protease is added, 45min is hydrolyzed at 7 DEG C, centrifuges, after being extracted with ethyl alcohol, removes ethyl alcohol, the yolk purified
Oil.
(2) it is 8.5 according to mass ratio:19：16.5, by polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole
Alkanol is added to the water, and after being sufficiently stirred dissolving, is warming up to 97 DEG C and continues to stir 30min, be then cooled to room temperature addition and account for always
The content of volume is that 0.8% initiator Irgacure2959 cures after first curing 14s under 11W power under 45W power
40s obtains the acrylic hydrogel that the degree of cross linking is 27%.
(3) after freezing acrylic hydrogel at -25 DEG C, it is dried in vacuo 1.5d, obtains dry acrylic hydrogel.
(4) dry acrylic hydrogel is taken out, it is 1 that volume ratio is added at room temperature:0.35 egg oil and metal salt
Solution, wherein metal salt solution are that mass ratio is 9.5:1 plumbi nitras and the mixed solution of lanthanum nitrate, first with the speed of 75r/min
After rate stirs 6min, stirring to acrylic hydrogel is continued with the rotating speed of 270r/min and restores to room temperature to obtain fully after absorption
The acrylic gel of loading metal-salt containing egg oil, wherein the acrylic gel mesolecithal of the loading metal-salt containing egg oil
The content of the loading metal-salt of oil is not less than 15%.
(5) acrylic gel containing egg oil is slowly added into after maturation process in liposome, is stirred evenly, 4
It is swollen overnight under DEG C environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome, wherein oil/lipid containing yolk
The content of liposome is 16% in the electromagnetic shielding medical gel material of body.
After testing, the mechanical property for the electromagnetic shielding medical gel material containing egg oil/liposome that prepared by embodiment 1-6
It is as follows with the result of electromagnetic shielding：
As seen from the above table, the shielding for the electromagnetic shielding medical gel material containing egg oil/liposome that prepared by the present invention
Energy and excellent in mechanical performance can play the effect protected and treated for a long time.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe
The personage for knowing this technology can all carry out modifications and changes to above-described embodiment without violating the spirit and scope of the present invention.Cause
This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as
At all equivalent modifications or change, should by the present invention claim be covered.
Claims (10)
1. a kind of preparation method of the electromagnetic shielding medical gel material containing egg oil/liposome, which is characterized in that including following
Step：
(1) yolk that will be cooked crush it is dry after, be added to the water uniformly mixed, protease hydrolytic be added, centrifugation is extracted with ethyl alcohol
Afterwards, ethyl alcohol, the egg oil purified are removed；
(2) polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol are added to the water, are sufficiently stirred dissolving
Afterwards, it is warming up to 90-100 DEG C to continue to stir 30min, is then cooled to room temperature addition initiator, through ultraviolet curing, obtains propylene
Acid hydrogel；
(3) after freezing acrylic hydrogel prepared by step (2) at -20~-30 DEG C, vacuum drying obtains dry third
Olefin(e) acid hydrogel；
(4) acrylic hydrogel for the drying for preparing step (3) takes out, and egg oil prepared by step (1) is added at room temperature
And metal salt solution, it is slowly stirred to acrylic hydrogel and restores to obtain the gold-supported containing egg oil fully after absorption to room temperature
Belong to the acrylic gel of salt；
(5) acrylic gel containing egg oil for preparing step (4) is slowly added into liposome, stirs after maturation process
It mixes uniformly, is swollen overnight under 4 DEG C of environment, obtains the electromagnetic shielding medical gel material containing egg oil/liposome.
2. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (1), the temperature of hydrolysis is 4-8 DEG C, time 30-90min.
3. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (2), polyethyleneglycol diacrylate, polyethylene glycol and polyvinyl pyrrole alkanol mass ratio
For 8-10:12-20：16-18.
4. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (2), initiator Irgacure2959, content 0.5-1%.
5. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (2), the condition of ultraviolet curing is, after first curing 10-15s under 10-15 power, in 30-
Cure 30-45s under 50W power.
6. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (2), the degree of cross linking of acrylic hydrogel is 25-28%.
7. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (3), the vacuum drying time is 0.5-2d.
8. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (4), the volume ratio of egg oil and metal salt solution is 1:0.3-0.5, metal salt solution are matter
Amount is than being 8-10:1 plumbi nitras and the mixed solution of lanthanum nitrate.
9. a kind of preparation method of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1,
It is characterized in that：In the step (4), the loading metal-salt of the acrylic gel mesolecithal oil of the loading metal-salt containing egg oil
Content be not less than 15%.
10. a kind of preparation side of electromagnetic shielding medical gel material containing egg oil/liposome according to claim 1
Method, it is characterised in that：In the step (5), liposome contains in the electromagnetic shielding medical gel material containing egg oil/liposome
Amount is 12-18%.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115872769A (en) * | 2022-11-03 | 2023-03-31 | 常州大学 | Method for preparing block ceramic aerogel with good heat insulation and electromagnetic shielding performance by using waste lead-acid battery anode material at low temperature |
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| CN101157744A (en) * | 2007-09-11 | 2008-04-09 | 浙江大学 | Method for grafting polymer on metal material surface |
| CN102670466A (en) * | 2012-05-24 | 2012-09-19 | 中国中医科学院中药研究所 | Moisture-retaining micro-emulsion gel containing egg yolk oil, and preparation method thereof |
| CN105658204A (en) * | 2013-10-29 | 2016-06-08 | 华斯泰株式会社 | Method for physically encapsulating, in hydrogel particle, liposome containing active ingredient, and cosmetic composition containing same |
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| CN101157744A (en) * | 2007-09-11 | 2008-04-09 | 浙江大学 | Method for grafting polymer on metal material surface |
| CN102670466A (en) * | 2012-05-24 | 2012-09-19 | 中国中医科学院中药研究所 | Moisture-retaining micro-emulsion gel containing egg yolk oil, and preparation method thereof |
| CN105658204A (en) * | 2013-10-29 | 2016-06-08 | 华斯泰株式会社 | Method for physically encapsulating, in hydrogel particle, liposome containing active ingredient, and cosmetic composition containing same |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115872769A (en) * | 2022-11-03 | 2023-03-31 | 常州大学 | Method for preparing block ceramic aerogel with good heat insulation and electromagnetic shielding performance by using waste lead-acid battery anode material at low temperature |
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