CN108617872A - Somatotrophic pig feed additive of a kind of raising immunity and its preparation method and application - Google Patents

Somatotrophic pig feed additive of a kind of raising immunity and its preparation method and application Download PDF

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Publication number
CN108617872A
CN108617872A CN201810442286.7A CN201810442286A CN108617872A CN 108617872 A CN108617872 A CN 108617872A CN 201810442286 A CN201810442286 A CN 201810442286A CN 108617872 A CN108617872 A CN 108617872A
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China
Prior art keywords
parts
feed additive
curcumin
sodium
pig feed
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CN201810442286.7A
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Inventor
黄坚
金赛勉
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JIANGXI WANGDA ANIMAL TECHNOLOGY Co Ltd
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JIANGXI WANGDA ANIMAL TECHNOLOGY Co Ltd
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Priority to CN201810442286.7A priority Critical patent/CN108617872A/en
Publication of CN108617872A publication Critical patent/CN108617872A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/28Silicates, e.g. perlites, zeolites or bentonites
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

The present invention relates to field of fodder, and in particular to somatotrophic pig feed additive of a kind of raising immunity and its preparation method and application.The feed addictive, by weight, including:15 parts of 6 parts of 4 parts of xylo-oligosaccharide, 15 parts of sodium humate and curcumin, 0.08 part of sodium benzoate and starch.Preparation method is to carry out xylo-oligosaccharide, sodium humate and curcumin remaining auxiliary materials and mixing to be added after tentatively mixing to obtain the final product.The feed addictive of the present invention, can significantly improve the production performance of growing and fattening pigs, reduces its Incidence of Diarrhea, and can effectively improve the immune function of growing and fattening pigs.

Description

Somatotrophic pig feed additive of a kind of raising immunity and its preparation method and application
Technical field
The present invention relates to feed additive fields, and in particular to a kind of somatotrophic pig feed additive of raising immunity and Preparation method and application.
Background technology
Pig just becomes growing and fattening pigs after nursing period, child care phase, growth period, and growing and fattening pigs are that growth speed of pigs is most fast and feed consumption Measure the maximum stage.The upgrowth situation of this stage pig, which delivers the later stage for sale, plays vital influence, as being carried in this stage The production performance of high pig can then significantly improve raising quality, shorten Time To Market.So this stage is to cultivate pig quality most Crucial period positive will also prevent and cure diseases in addition to ensure enough nutrition and energy.As pig breeding industry scale is sent out It opens up, the additives such as somatotropin, chemicals and antibiotic in feed, has certain effect to growth promotion, prevention disease, but It results in and develops immunity to drugs, livestock products medicament residue and jeopardizes the new problems such as health of people.
Therefore, it for the industry, designs a kind of antibiotic-free and with safe and non-toxic, has the function of disease-prevention health and simultaneous Aquaculture cost problem is cared for, and the feed addictive that can meet the nutritional need of growing and fattening pigs becomes urgent problem to be solved.
Invention content
For the above-mentioned shortcoming of the prior art, the present invention provide it is a kind of improve pig immunity feed addictive and its The ingredient of preparation method, the feed addictive is simple, can effectively be played in the growth course of pig and improve immunity and rush The effect of growth.
One of the objects of the present invention is to provide a kind of feed addictives improving pig immunity, by weight, including Following raw material:5 parts~10 parts of 1 part~5 parts of xylo-oligosaccharide, 5 parts~25 parts of sodium humate and curcumin.
Further, by weight, which includes following raw material:3 parts~5 parts of xylo-oligosaccharide, humic acid 5 parts~7 parts of 10 parts~20 parts of sodium and curcumin.
Further, by weight, which includes following raw material:4 parts of xylo-oligosaccharide, 15 parts of sodium humate With 6 parts of curcumin.
Further, by weight, which further includes 0.05 part~0.1 part of mould inhibitor, Appetizer 0.01 part~0.1 part and 5 parts~30 parts of diluent.
Further, the mould inhibitor is one or more in sodium propionate, sodium benzoate and potassium sorbate.
Further, the Appetizer is selected from orange meal, sodium glutamate, edible sodium chloride, citric acid, lactose and wheat It is one or more in bud sugar.
Further, the diluent is one or more in starch, talcum powder and maize cob meal.
The second object of the present invention is to provide a kind of preparation method improving the somatotrophic pig feed additive of immunity, press Mass parts meter, includes the following steps:
(1) 5 parts~10 parts of 1 part~5 parts of xylo-oligosaccharide, 5 parts~25 parts of sodium humate and curcumin are uniformly mixed and are obtained Mixture;
(2) 0.05 part~0.1 part of mould inhibitor, 0.01 part~0.1 part of Appetizer and diluent 5 are added in the mixture Part~30 parts, mixing to obtain the final product.
The third object of the present invention is to provide the feed addictive in preparing the raising somatotrophic pannage of immunity Application, by weight, adding proportion of the feed addictive in feed be 0.5%~1.0%, feed of the invention adds Add agent that can be added in any kind of pannage as feed addictive.
Compared with prior art, the invention has the advantages that:
1. feed addictive provided by the invention includes xylo-oligosaccharide, sodium humate and curcumin as active ingredient, and three Person, which cooperates, has synergistic effect, is used for the feed addictive of growing and fattening pigs, can significantly improve production performance, the drop of growing and fattening pigs Its low Incidence of Diarrhea, and can effectively improve the immune function of growing and fattening pigs.
2. the feed addictive prescription of the present invention is simple, safe, the noresidue of each ingredient is growth-promoting class antibiotic Effective substitute products.
3. the preparation method of the feed addictive of the present invention, simple and reliable process can realize industrialized production.
Specific implementation mode
The present invention is further described with reference to embodiments, it should be appreciated that these embodiments are not constituted to this hair Bright limitation.
Experimental method in following embodiments, unless otherwise specified, involved raw materials and reagents are common commercially available product, all It can be bought and be obtained by market.
Curcumin is a kind of chemical composition extracted from the rhizome of some plants in Zingiber, Araeceae, and medicine is ground Study carefully and shows that curcumin has the effects that reducing blood lipid, antitumor, anti-inflammatory, cholagogic, anti-oxidant.The curcumin that the present invention uses is purchased from Hainan Jin Tairui Bioisystech Co., Ltd.
Xylo-oligosaccharide is faint yellow or light tan powder, is combined into β-Isosorbide-5-Nitrae glycosidic bond by 2-7 xylose molecule Functional polymerization sugar has preferable absolute acid stability and thermal stability.Bifidobacterium in animal intestinal tract can be given with high selectivity Equal beneficial bacteriums provide culture substrate, and stimulation beneficial bacterium is largely proliferated rapidly, forms best micro-ecological environment in enteron aisle, significantly improve Breeding performonce fo animals;Body immune system is activated, animal immunizing power is improved, reduces the death rate and dosage;Promote growth of animal, Reduce serum cholesterol levels, to animal have extensive health-care effect, while itself have it is heat-resisting, pollution-free, without residual The physicochemical property stayed is the feed addictive of green.The xylo-oligosaccharide of the present invention is purchased from the limited public affairs of moral biotechnology of Wuhan letter Department.
Sodium humate is pitch-black indefiniteness particle, is processed through special process using weathered coal, peat and lignite as raw material A kind of manufactured macromolecular organic monoacid sodium salt with multiple functions, it is nontoxic odorless corrosion-free, is highly soluble in water.It is main to use In convergence, hemostasis, antidiarrheal.For spitting blood, have blood in stool, diarrhea is vomitted, epigastric pain, baby diarrhea, spleen deficiency chronic diarrhea, protracted dysentery.It is one Kind produces the good veterinary drug and feed addictive of green newborn meat and egg production.The sodium humate that the present invention uses is purchased from Jinan Fu Ji Chemical Co., Ltd..
Embodiment 1:
A kind of feed addictive improving pig immunity, by weight, including:4 parts of xylo-oligosaccharide, 15 parts of sodium humate With 15 parts of 6 parts of curcumin, 0.08 part of sodium benzoate and starch.Preparation method be by xylo-oligosaccharide, sodium humate and curcumin into Remaining auxiliary materials and mixing is added after the preliminary mixing of row to obtain the final product.
Embodiment 2:
A kind of feed addictive improving pig immunity, by weight, including:3 parts of xylo-oligosaccharide, 20 parts of sodium humate With 5.0 parts of 8 parts of curcumin, 0.1 part of sodium propionate, 0.05 part of sodium glutamate and talcum powder.Preparation method is by xylo-oligosaccharide, humic Sour sodium and curcumin carry out remaining auxiliary materials and mixing being added after tentatively mixing to obtain the final product.
Embodiment 3:
A kind of feed addictive improving pig immunity, by weight, including:5 parts of xylo-oligosaccharide, 25 parts of sodium humate With 30 parts of 10 parts of curcumin, 0.1 part of potassium sorbate, 0.05 part of citric acid and starch.Preparation method is by xylo-oligosaccharide, humic acid Sodium and curcumin carry out remaining auxiliary materials and mixing being added after tentatively mixing to obtain the final product.
Embodiment 4:
A kind of feed addictive improving pig immunity, by weight, including:1 part of xylo-oligosaccharide, 15 parts of sodium humate With 20 parts of 5 parts of curcumin, 0.05 part of sodium benzoate, 0.05 part of lactose, 0.05 part of orange meal and talcum powder.Preparation method is will be low Xylan, sodium humate and curcumin carry out remaining auxiliary materials and mixing being added after tentatively mixing to obtain the final product.
Embodiment 5:
A kind of feed addictive improving pig immunity, by weight, including:3 parts of xylo-oligosaccharide, 10 parts of sodium humate With 10 parts of 5 parts of curcumin, 0.1 part of sodium benzoate, 0.08 part of lactose, 0.02 part of orange meal and talcum powder.Preparation method is will be low Xylan, sodium humate and curcumin carry out remaining auxiliary materials and mixing being added after tentatively mixing to obtain the final product.
Embodiment 6:
A kind of feed addictive improving pig immunity, by weight, including:5 parts of xylo-oligosaccharide, 20 parts of sodium humate With 20 parts of 7 parts of curcumin, 0.05 part of sodium benzoate, 0.1 part of maltose and talcum powder.Preparation method is by xylo-oligosaccharide, humic Sour sodium and curcumin carry out remaining auxiliary materials and mixing being added after tentatively mixing to obtain the final product.
Embodiment 7:
1. experimental animal and grouping
Select that age in days is close, weight 60kg or so, the tri-crossbreeding 150 that health is disease-free, male and female close according to weight Fifty-fifty principle is randomly divided into 5 groups, and every group of 3 repetitions, each to repeat 10, raising is grouped as follows:
1st group is blank control group, feeds basal diet, and the 2nd group is test group, and 0.5% (weight is added in feeding daily ration Amount) embodiment 1 feed addictive, the 3rd group in feed daily ration add 0.5% (weight) comparative example 1 feed addictive (general Sodium humate and curcumin are substituted with starch, remaining is with embodiment 1), the 4th group in feeding daily ration add 0.5% (weight) it is right The feed addictive (substituting sodium humate and xylo-oligosaccharide with starch, remaining is with embodiment 1) of ratio 2 and the 5th group are being fed The feed addictive that 0.5% (weight) comparative example 3 is added in daily ration (is substituted curcumin and xylo-oligosaccharide with starch, remaining is same Embodiment 1).
Diet Formula:Corn 70.92%, Soybean Meal 17.21%, wheat bran 3.00%, the corn alcohol dregs of rice 2.62%, rapeseed dregs 1.9%, calcium monohydrogen phosphate 1.17%, mountain flour 0.87, salt 0.21, premix 2.00, choline chloride 0.10;
Premix provides for per kilogram daily ration:Cu15mg;Fe80mg;Zn 80mg;Mn 5mg;I 0.14mg;Se 0.25mg;Vitamin A 6000IU;Vitamin D3300IU;Vitamin E 45mg;Vitamin K33.5mg;Vitamin B13.2mg;Dimension Raw element B26.25mg;Vitamin B55mg;Vitamin B120.025mg;Niacin 35mg;Calcium pantothenate 33mg;Folic acid 1.2mg;Biology Plain 0.4mg;Vitamin C 260mg.
2. experimental design
Using the experimental design of single factor test, test pig is flat foster using ground, each repeats individually to be fed, freely drink for experiment Water, daily feeding 3 times (6:00,12:30 and 18:30), daily management is routinely carried out with immune programme, to pig after feeding 4 weeks It only weighs, calculates its production performance.During feeding, Incidence of Diarrhea is counted, off-test carries out blood parameters survey It is fixed.
3. testing index
(1) growth performance:It weighs on an empty stomach respectively before experiment and when off-test.Precise tests materials, calculates Feedstuff-meat ratio assesses feed efficiency.
(2) Incidence of Diarrhea:The swine excrement situation of timing observation sooner or later, excrement are divided into normally daily, dilute soft, sticky, water sample With 5 grades of bloody stool, rear 4 grades are determined as diarrhea, calculate Incidence of Diarrhea=(diarrhea number/(pig number during experiment Measure * test periods)) * 100%;
(3) blood parameters measure:In off-test, 2 test pigs of each repetition random selection, morning empty stomach, Every pig ear vein blood sampling, after standing 15min, 2500r/min centrifugations take upper serum to preserve standby survey in -20 DEG C of refrigerators.It adopts Immunoglobulin in Serum IgA, IgG, IgM and Complement C_3, C4 are measured with Immunity transmission turbidity;It is counted using radio-immunity Method measures the content of FT3 (triiodo thryonine) and FT4 (free thyroxine) in serum.
4. result and analysis
Each processing group production performance, diarrhea situation and the blood parameters situation table of comparisons are shown in Table 1-3 respectively
Table 1:Each processing group growth performance table of comparisons
Note:In the same row, the female difference person of institute's marking-up above the right shoulder of measured value, shows significant difference (P < to each other 0.05), similarly hereinafter
As known from Table 1, each index of the production performance of growing and fattening pigs, compared with blank control group (the 1st group), each test group is all It increases, but the 2nd group is put up the best performance, especially daily gain significantly improves, and feedstuff-meat ratio significantly reduces, and illustrates and comparative example 1-3 It compares, the feed addictive that the present invention is added in feed is remarkably improved the feed conversion rate of growing-finishing pig, is conducive to carry Rise the production performance of growing and fattening pigs.
Table 2:Each processing group diarrhea situation table
By table 2 it is found that in addition to the 4th group, remaining processing group compared with blank control group (the 1st group), testing by growing and fattening pigs The Incidence of Diarrhea of period has reduction, but the 2nd group of Incidence of Diarrhea is minimum, illustrates, the feeding of the present invention is added in feed Feed additives can significantly improve the diarrhea situation of growing and fattening pigs.
Table 3:Each processing group blood parameters situation table
By table 3 it is found that 2-3 groups and the 5th group are compared with blank control group (the 1st group), growing and fattening pigs are during experiment Immunoglobulin content, complement concentration and Triiodothyronine are improved, and significant difference, the 4th group compared with the 1st group, IgM It is improved with being seen in the content of Complement C_3 and FT3, and significant difference;And the 2nd group (experimental group) and 3-5 groups (comparative example) phase Than indices are also improved, and significant difference, illustrate have between each component in the feed addictive of the embodiment of the present invention 1 Synergistic effect, with the use of the immune function that can significantly improve growing and fattening pigs.

Claims (9)

1. a kind of somatotrophic pig feed additive of raising immunity, which is characterized in that by weight, including following raw material: 5 parts~10 parts of 1 part~5 parts of xylo-oligosaccharide, 5 parts~25 parts of sodium humate and curcumin.
2. pig feed additive according to claim 1, which is characterized in that by weight, including following raw material:It is oligomeric 5 parts~7 parts of 3 parts~5 parts of xylose, 10 parts~20 parts of sodium humate and curcumin.
3. pig feed additive according to claim 1, which is characterized in that by weight, including following raw material:It is oligomeric 6 parts of 4 parts of xylose, 15 parts of sodium humate and curcumin.
4. according to claims 1 to 3 any one of them pig feed additive, which is characterized in that further include 0.05 part of mould inhibitor 5 parts~30 parts of~0.1 part, 0.01 part~0.1 part of Appetizer and diluent.
5. pig feed additive according to claim 4, which is characterized in that the mould inhibitor is selected from sodium propionate, benzoic acid It is one or more in sodium and potassium sorbate.
6. pig feed additive according to claim 4, which is characterized in that the Appetizer is selected from orange meal, paddy It is one or more in propylhomoserin sodium, edible sodium chloride, citric acid, lactose and maltose.
7. pig feed additive according to claim 4, which is characterized in that the diluent be selected from starch, talcum powder and It is one or more in maize cob meal.
8. a kind of preparation method improving the somatotrophic pig feed additive of immunity, which is characterized in that in parts by mass, including Following steps:
(1) 5 parts~10 parts of 1 part~5 parts of xylo-oligosaccharide, 5 parts~25 parts of sodium humate and curcumin are mixed Object;
(2) be added in the mixture 0.05 part~0.1 part of mould inhibitor, 5 parts of 0.01 part~0.1 part of Appetizer and diluent~ 30 parts, mixing to obtain the final product.
9. any one of claim 1~7 feed addictive, which is used to prepare, improves answering in the somatotrophic pannage of immunity With, which is characterized in that by weight, adding proportion of the feed addictive in feed is 0.5%~1.0%.
CN201810442286.7A 2018-05-10 2018-05-10 Somatotrophic pig feed additive of a kind of raising immunity and its preparation method and application Pending CN108617872A (en)

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Publication number Priority date Publication date Assignee Title
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CN104187179A (en) * 2014-09-18 2014-12-10 刘鹏 Piglet compound feed and preparation method thereof
CN105254683A (en) * 2015-11-06 2016-01-20 中国农业科学院饲料研究所 Alpha-type xylooligosaccharide and preparation method and applications thereof
CN105325724A (en) * 2015-11-03 2016-02-17 深圳市澳华农牧有限公司 Compound fodder additive for pigs and preparing method and application thereof
CN107712356A (en) * 2017-11-20 2018-02-23 四川檀榕动物营养食品有限公司 A kind of feed addictive and preparation method thereof, feed
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CN102202520A (en) * 2008-07-31 2011-09-28 泰国研究基金会 Feed for poultry and swine
CN104187179A (en) * 2014-09-18 2014-12-10 刘鹏 Piglet compound feed and preparation method thereof
CN105325724A (en) * 2015-11-03 2016-02-17 深圳市澳华农牧有限公司 Compound fodder additive for pigs and preparing method and application thereof
CN105254683A (en) * 2015-11-06 2016-01-20 中国农业科学院饲料研究所 Alpha-type xylooligosaccharide and preparation method and applications thereof
CN107712356A (en) * 2017-11-20 2018-02-23 四川檀榕动物营养食品有限公司 A kind of feed addictive and preparation method thereof, feed
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Application publication date: 20181009