CN108578502A - A kind of Chinese medicine composition and preparation method thereof of nourishing the stomach protect liver - Google Patents

A kind of Chinese medicine composition and preparation method thereof of nourishing the stomach protect liver Download PDF

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Publication number
CN108578502A
CN108578502A CN201810137023.5A CN201810137023A CN108578502A CN 108578502 A CN108578502 A CN 108578502A CN 201810137023 A CN201810137023 A CN 201810137023A CN 108578502 A CN108578502 A CN 108578502A
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chinese medicine
stomach
nourishing
raw material
parts
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黄文科
赵志方
刘康
闫岩
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Heng Kang Bao Health Science And Technology (beijing) Co Ltd
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Heng Kang Bao Health Science And Technology (beijing) Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of Chinese medicine composition of nourishing the stomach protect liver, raw material include pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel.The method for preparing the nourishing the stomach liver protection traditional Chinese medicine combination is additionally provided, the Chinese medicine composition of the present invention is prepared into the dosage forms such as hard candy, lozenge, pill, cake.The advantage of the invention is that, nourishing the stomach liver-protecting combination provided by the invention, realize the synergy between every drug, the advantage of prescription is far longer than the effect that the superposition of simple timber-used amount uses, but also it avoids, because of side effect caused by the superposition use of single medicinal material, significantly improving the effect of nourishing the stomach protect liver.

Description

A kind of Chinese medicine composition and preparation method thereof of nourishing the stomach protect liver
Technical field
The invention belongs to health product technology field, specially a kind of Chinese medicine composition and preparation method thereof of nourishing the stomach protect liver.
Background technology
With the gradual quickening of Working Life rhythm, more and more personages etc. that work have the discomfort of stomach and liver often, The main reason for causing chemically liver gastric injury has the following aspects:First, overwork of staying up late.It is busy with one's work, often stays up late, sleep It sleeps insufficient, excessive fatigue can cause liver blood flow relative deficiency, and the nutrition for influencing liver cell is moistened, and resistance declines, and causes Liver cell in damaged condition be difficult to repair and it is exacerbated;Second, drinking too much.Long-term or discontinuity heavy drinking can cause stomach and liver Damage.Big, the lasting Ganderwa of drinking amount is longer, and consequence is more serious.Alcohol can directly poison stomach and liver cell, influence its structure And function.Third, environmental pollution.Living environment deteriorates seriously, and full of industrial waste gas, vehicle exhaust in air, working environment is empty Gas is dirty, so that the harmful substance of sucking is increased, liver injury.4th, drug administration.Some drugs take for a long time or overdose Can stomach and liver be caused to damage.The damage of these stomach and livers often can not check specific illness in physical examination, but sense of discomfort can influence people Normal work and life, people's health but will be influenced in the course of time, so, how to prepare alleviate the various discomforts of stomach and liver, Long-term consumption helps that stomach and liver is restored and the health products that have no toxic side effect are urgent problems to be solved currently on the market.
Invention content
Alleviate the various discomforts of stomach and liver to solve to lack in the prior art, long-time service helps stomach and liver and restores and have no toxic side effect The defect of health products, the present invention provides a kind of Chinese medicine composition and preparation method thereof of nourishing the stomach protect liver, the purpose of realization is To a kind of Chinese medicine composition of the nourishing the stomach protect liver of instant edible, nourishing the stomach protect liver effect is good, and long-term consumption has no toxic side effect.
To achieve the goals above, the present invention provides following technical scheme:In a kind of nourishing the stomach protect liver provided by the invention The raw material of drug composition, the composition include pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel.
Further, pueraria lobata 30-150 parts, 10-60 parts of Hericium erinaceus, 10-60 parts of Radix Glycyrrhizae, 10-60 parts of jujube, dried orange peel 10-60 Part, the number each means parts by weight of each ingredient in raw material.
Pueraria lobata that the present invention selects, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel are all the food materials of medicine-food two-purpose, and pueraria lobata has expelling pathogenic factors from muscles and skin It brings down a fever, promoting eruption promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie.It is usually used in exterior syndrome fever, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, cloudy Void is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.《Compendium of Materia Medica》In record in this way:" Pueraria lobota, property is sweet, pungent, flat, nontoxic, cures mainly:Quench one's thirst, High fever of the body, vomiting, all disadvantages play cloudy gas, solve all poison ".
Hericium erinaceus relieving the five internal organs, aid digestion, nourishing, anticancer, treatment neurasthenia.
Radix Glycyrrhizae is invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription,《Herbal solutions》:The vital organs of the human body Fever and chills perverse trend, hard muscles and bones, long muscle, times strength, metal-inflicted wound, removing toxic substances.
Jujube tonifying middle-Jiao and Qi, nourishing blood and tranquilization.《Herbal solutions》:Supported in main trusted subordinate's perverse trend peace temper flat stomach gas, logical nine orifices, The few gas of 12 warps, benefit is helped to lack insufficient, frightened heaviness of limbs and hundred medicines in body fluid, body.
Dried orange peel regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.《Herbal solutions》:Temperature, bitterly, nontoxic, main lump in the abdomen heat in the heart are against gas, Li Shui Paddy, long term usage deodorizing, the logical god of lower gas.
Present invention discover that the various discomforts of stomach and liver can be alleviated using the composition that above-mentioned raw material compatibility obtains, realize each Synergy between the raw material of position, the advantage of prescription is far longer than the effect that the superposition of simple timber-used amount uses, but also keeps away Exempt from, because of side effect caused by the superposition use of single medicinal material, to significantly improve the ability of nourishing the stomach protect liver.
The present invention also provides the methods for preparing Chinese medicine composition of the present invention, and this method comprises the following steps:
By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material, add flooding, the mass ratio of raw material and water is 1:6- 15, it extracts 2-4 times, every time extraction 0.5-3 hours, 90-100 DEG C of Extracting temperature merges extracting solution, extracting solution 100-400 mesh mistakes Filter refines under the conditions of concentration vacuum degree -0.06~-0.08MPa, 60-80 DEG C of temperature, dry to biodiversity content≤5% After hard candy be made, lozenge, chewable tablets, swallow any one agent in tablet, granule, pulvis, paste, oral solution, syrup, beverage Type.
The method for preparing Chinese medicine composition of the present invention can also use following methods:By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, Dried orange peel raw material are ground into the above fine powder of 60-120 mesh, and mixing 0.5-1.5 hour is to being made in hard capsule, pill arbitrarily after uniformly A kind of dosage form.
The method for preparing Chinese medicine composition of the present invention can also use following methods:By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, Dried orange peel raw material ultramicro grinding, mixing 0.5-1.5 hour is to being made hard candy after uniform, soft capsule, lozenge, chewable tablets, gulp down Take any one dosage form in tablet, granule, pulvis, medicinal tea, paste, cake.
Preferably, it is filtered using filter plate or filter membrane in the filtering, pore size filter is 1 micron or 0.45 micron.Make Manufactured product can keep clarifying during storage, but also manufactured product can be clarified rapidly during preparation.
Preferably, when the Chinese medicine composition is prepared into beverage formulations, by raw material through extraction, filtering, concentration, refined It sterilizes again afterwards and beverage is made, sterilizing methods are flash-sterilization or moist heat sterilization, and sterilising temp is 130 DEG C, and sterilization time is 10s;110 DEG C of the moist heat sterilization temperature degree, sterilization time 30min.Not only the purpose of disinfection had been played, but also can guarantee product Flavor and stabilization.
The present invention uses above-mentioned technical proposal, including following advantageous effect:Nourishing the stomach liver-protecting combination provided by the invention, it is real Showing the synergy between every drug, the advantage of prescription is far longer than the effect that the superposition of simple timber-used amount uses, and And it also avoids, because of side effect caused by the superposition use of single medicinal material, significantly improving the effect of nourishing the stomach protect liver, being suitable for work It is busy, it often stays up late, has not enough sleep, excessive fatigue, drinking too much, the crowd for taking chemicals for a long time.
Specific implementation mode
The present invention is described in further detail below by specific embodiment.In the present invention without specified otherwise , operation technique and step are the prior arts used, and the parameters such as operating condition of specified otherwise, are not normal in room temperature Under the conditions of pressure.
Embodiment one:A kind of Chinese medicine composition disclosed by the invention, raw material include pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, The number of dried orange peel, each ingredient is:30 parts of pueraria lobata, 10 parts of Hericium erinaceus, 10 parts of Radix Glycyrrhizae, 10 parts of jujube, 10 parts of dried orange peel, the number is equal Refer to parts by weight of each ingredient in raw material.Prior art either method can be used to be prepared into Chinese medicine composition of the present invention It is edible, it is prepared into Chinese medicinal decoction for example, by using the decocting method of the prior art.
Chinese medicinal decoction made of embodiment one is drunk to 100 personages that are on the drink, 2 times a day, is continuously taken 21 days, 90% people has a stomach upset improving situation after drinking, uncomfortable mitigation after being still drank after a night, and illustrates that the Chinese medicine composition of the present invention can delay The discomfort of stomach and liver is solved, and stomach and liver is helped quickly voluntarily to restore.
Embodiment two:A kind of nourishing the stomach liver protection traditional Chinese medicine combination disclosed by the invention, raw material include pueraria lobata, Hericium erinaceus, sweet The number of grass, jujube, dried orange peel, each ingredient is:150 parts of pueraria lobata, 60 parts of Hericium erinaceus, 60 parts of Radix Glycyrrhizae, 60 parts of jujube, 60 parts of dried orange peel, The number each means parts by weight of each ingredient in raw material.
It is preferred that Chinese medicine composition of the present invention to be prepared into the dosage form of instant edible with the following method:
By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material, add flooding, the mass ratio of raw material and water is 1:6, Extraction 2 times, extraction 0.5 hour, 90 DEG C of Extracting temperature, merge extracting solution every time, and the filtering of extracting solution 100-400 mesh is true in concentration Reciprocal of duty cycle -0.06MPa is refined under the conditions of temperature 60 C, dry to hard candy, lozenge, chewing is made after biodiversity content≤5% Piece swallows any one dosage form in tablet, granule, pulvis, paste, oral solution, syrup, beverage.
In influence of the Extracting temperature to product active ingredient under the same conditions of amount of water, extraction time and extraction time, It is as follows as judge index (Puerarin contained in raw material is based on 100%) result using Puerarin:
Influence of the temperature to Puerarin recovery rate
Temperature (DEG C) Puerarin recovery rate (%)
80-90 64.1
90-100 88.6
100 or more 72.3
The experimental results showed that:The recovery rate highest of Puerarin when 90-100 DEG C of Extracting temperature.
Embodiment three:A kind of nourishing the stomach liver protection traditional Chinese medicine combination disclosed by the invention, raw material include pueraria lobata, Hericium erinaceus, sweet The number of grass, jujube, dried orange peel, each ingredient is:100 parts of pueraria lobata, 30 parts of Hericium erinaceus, 30 parts of Radix Glycyrrhizae, 30 parts of jujube, 30 parts of dried orange peel, The number each means parts by weight of each ingredient in raw material.
It is preferred that Chinese medicine composition of the present invention to be prepared into the dosage form of instant edible with the following method:
Pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material are ground into the above fine powder of 60-120 mesh, are mixed 0.5 hour To uniformly after any one dosage form in hard capsule, pill is made.
Hard capsule, pill made of the present embodiment are drunk to 100 personages that are on the drink, 2 times a day, continuously take 21 It, 90% people stomach and liver portion discomfort improving situation after drinking, uncomfortable mitigation after being still drank after a night, and follow-up 1 year without have a stomach-ache again, liver not The symptoms such as suitable illustrate that the Chinese medicine composition of the present invention can alleviate the discomfort of stomach and liver, and help stomach and liver quickly voluntarily extensive It is multiple.
Example IV:A kind of nourishing the stomach liver protection traditional Chinese medicine combination disclosed by the invention, raw material include pueraria lobata, Hericium erinaceus, sweet The number of grass, jujube, dried orange peel, each ingredient is:40 parts of pueraria lobata, 20 parts of Hericium erinaceus, 20 parts of Radix Glycyrrhizae, 20 parts of jujube, 20 parts of dried orange peel, institute It states number and each means parts by weight of each ingredient in raw material.
It is preferred that Chinese medicine composition of the present invention to be prepared into the dosage form of instant edible with the following method:By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material ultramicro grinding, mixing 1.5 hours to uniformly after hard candy, soft capsule, lozenge, chewing is made Piece swallows any one dosage form in tablet, granule, pulvis, medicinal tea, paste, cake.
Soft capsule, lozenge etc. made of the present embodiment are drunk to 100 personages that are on the drink, 2 times a day, continuously taken 21 days, 90% people's stomach and liver portion discomfort improving situation, uncomfortable mitigation after being still drank after a night after drinking, and follow-up 1 year nothing has a stomach-ache again, liver The symptoms such as discomfort illustrate that the Chinese medicine composition of the present invention can alleviate the discomfort of stomach and liver, and help stomach and liver quickly voluntarily Restore.
Embodiment five:A kind of nourishing the stomach liver protection traditional Chinese medicine combination disclosed by the invention, raw material include pueraria lobata, Hericium erinaceus, sweet The number of grass, jujube, dried orange peel, each ingredient is:140 parts of pueraria lobata, 50 parts of Hericium erinaceus, 50 parts of Radix Glycyrrhizae, 50 parts of jujube, 50 parts of dried orange peel, The number each means parts by weight of each ingredient in raw material.
It is preferred that Chinese medicine composition of the present invention to be prepared into the dosage form of instant edible with the following method:By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material, add flooding, and the mass ratio of raw material and water is 1:15, it extracts 4 times, every time extraction 3 hours, 100 DEG C of Extracting temperature merges extracting solution, extracting solution 100-400 mesh filtering, in concentration vacuum degree -0.08MPa, 80 DEG C of items of temperature Refined under part, it is dry to be made after biodiversity content≤5% hard candy, lozenge, chewable tablets, swallow tablet, granule, pulvis, Any one dosage form in paste, oral solution, syrup, beverage.
Food made of the present embodiment etc. is drunk to 100 personages that are on the drink, 2 times a day, is continuously taken 21 days, 90% people stomach and liver portion discomfort improving situation, uncomfortable mitigation after being still drank after a night after drinking, and follow-up 1 year nothing has a stomach-ache again, liver is uncomfortable Etc. symptoms, illustrate that the Chinese medicine composition of the present invention can alleviate the discomfort of stomach and liver, and stomach and liver helped quickly voluntarily to restore.
It is filtered using filter plate in the filtering, pore size filter is 1 micron.
When the Chinese medicine composition is prepared into beverage formulations, by raw material through extraction, filtering, concentration, it is refined after go out again Beverage is made in bacterium, and sterilizing methods are flash-sterilization, and sterilising temp is 130 DEG C, sterilization time 10s.
Embodiment six:A kind of nourishing the stomach liver protection traditional Chinese medicine combination disclosed by the invention, raw material include pueraria lobata, Hericium erinaceus, sweet The number of grass, jujube, dried orange peel, each ingredient is:75 parts of pueraria lobata, 40 parts of Hericium erinaceus, 40 parts of Radix Glycyrrhizae, 40 parts of jujube, 40 parts of dried orange peel, institute It states number and each means parts by weight of each ingredient in raw material.
It is preferred that Chinese medicine composition of the present invention to be prepared into the dosage form of instant edible with the following method:By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material, add flooding, and the mass ratio of raw material and water is 1:10, it extracts 2 times, extraction 1.5 is small every time When, 90-100 DEG C of Extracting temperature merges extracting solution, extracting solution 100-400 mesh filtering, in concentration vacuum degree -0.078MPa, temperature Refined under the conditions of 70 DEG C, it is dry to be made after biodiversity content≤5% hard candy, lozenge, chewable tablets, swallow tablet, granule, Any one dosage form in pulvis, paste, oral solution, syrup, beverage.
It is filtered using filter membrane in the filtering, pore size filter is 0.45 micron.
When the Chinese medicine composition is prepared into beverage formulations, by raw material through extraction, filtering, concentration, it is refined after go out again Bacterium is made beverage, and sterilizing methods are or moist heat sterilization 110 DEG C of the moist heat sterilization temperature degree, sterilization time 30min.
Food made of the present embodiment is drunk to 100 personages that are on the drink, 2 times a day, continuously takes 21 days, 90% People's stomach and liver portion discomfort improving situation after drinking, uncomfortable mitigation after being still drank after a night, and follow-up 1 year without have a stomach-ache again, the diseases such as liver discomfort Shape illustrates that the Chinese medicine composition of the present invention can alleviate the discomfort of stomach and liver, and stomach and liver is helped quickly voluntarily to restore.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, any made by repair Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (7)

1. a kind of Chinese medicine composition of nourishing the stomach protect liver, which is characterized in that the raw material of the composition include pueraria lobata, Hericium erinaceus, sweet Grass, jujube, dried orange peel.
2. the Chinese medicine composition of nourishing the stomach protect liver according to claim 1, which is characterized in that 30-150 parts of pueraria lobata, Hericium erinaceus 10-60 parts, 10-60 parts of Radix Glycyrrhizae, 10-60 parts of jujube, 10-60 parts of dried orange peel, the number each means each ingredient in raw material Parts by weight.
3. a kind of method preparing any one of claim 1-2 nourishing the stomach liver protection traditional Chinese medicine combinations, which is characterized in that should Method includes the following steps:
By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material, add flooding, the mass ratio of raw material and water is 1:6-15, leaching It carrying 1-4 times, every time extraction 0.5-3 hours, 90-100 DEG C of Extracting temperature, merges extracting solution, extracting solution 100-400 mesh filters, Vacuum degree -0.06~-0.08MPa is concentrated, refines under the conditions of 60-80 DEG C of temperature, is made after drying to biodiversity content≤5% Hard candy, chewable tablets, swallows any one dosage form in tablet, granule, pulvis, paste, oral solution, syrup, beverage at lozenge.
4. a kind of method preparing any one of claim 1-2 nourishing the stomach liver protection traditional Chinese medicine combinations, which is characterized in that should Method includes the following steps:Pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material are ground into the above fine powder of 60-120 mesh, are mixed 0.5-1.5 hour are closed to any one dosage form in hard capsule, pill is made after uniform.
5. a kind of method preparing any one of claim 1-2 nourishing the stomach liver protection traditional Chinese medicine combinations, which is characterized in that should Method includes the following steps:By pueraria lobata, Hericium erinaceus, Radix Glycyrrhizae, jujube, dried orange peel raw material ultramicro grinding, 0.5-1.5 hours are mixed extremely Hard candy is made after uniformly, soft capsule, lozenge, chewable tablets, swallows in tablet, granule, pulvis, medicinal tea, paste, cake and appoints It anticipates a kind of dosage form.
6. the method according to claim 3 for preparing nourishing the stomach liver protection traditional Chinese medicine combination, which is characterized in that adopted in the filtering It is filtered with filter plate or filter membrane, pore size filter is 1 micron or 0.45 micron.
7. the method according to claim 3 for preparing nourishing the stomach liver protection traditional Chinese medicine combination, which is characterized in that by the Chinese medicine group Object is closed when being prepared into beverage formulations, by raw material through extraction, filtering, concentration, it is refined after sterilize beverage is made again, sterilizing methods are Flash-sterilization or moist heat sterilization, sterilising temp are 130 DEG C, sterilization time 10s;110 DEG C of the moist heat sterilization temperature degree, Sterilization time is 30mi n.
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CN110583922A (en) * 2019-10-08 2019-12-20 深圳三九参智生态科技有限公司 Beverage for relieving alcoholism and preparation method thereof
CN113812487A (en) * 2021-09-29 2021-12-21 天津市农业科学院 Tea bag with stomach nourishing and digestion promoting functions and preparation method thereof

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Application publication date: 20180928