CN108578013B - 具有栓塞保护的插管器鞘 - Google Patents
具有栓塞保护的插管器鞘 Download PDFInfo
- Publication number
- CN108578013B CN108578013B CN201810228104.6A CN201810228104A CN108578013B CN 108578013 B CN108578013 B CN 108578013B CN 201810228104 A CN201810228104 A CN 201810228104A CN 108578013 B CN108578013 B CN 108578013B
- Authority
- CN
- China
- Prior art keywords
- embolic
- protection device
- filter
- embolic protection
- port
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000003073 embolic effect Effects 0.000 title claims abstract description 156
- 238000011144 upstream manufacturing Methods 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 22
- 230000017531 blood circulation Effects 0.000 claims description 7
- 239000011148 porous material Substances 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 4
- 239000000835 fiber Substances 0.000 claims description 4
- 229910052751 metal Inorganic materials 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims description 2
- 239000012781 shape memory material Substances 0.000 claims description 2
- 239000004745 nonwoven fabric Substances 0.000 claims 2
- 239000002759 woven fabric Substances 0.000 claims 2
- 230000002785 anti-thrombosis Effects 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 210000002376 aorta thoracic Anatomy 0.000 description 22
- 238000000034 method Methods 0.000 description 17
- 210000001765 aortic valve Anatomy 0.000 description 11
- 210000000709 aorta Anatomy 0.000 description 5
- 206010008088 Cerebral artery embolism Diseases 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 201000010849 intracranial embolism Diseases 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 4
- 238000007675 cardiac surgery Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000013152 interventional procedure Methods 0.000 description 3
- 238000002405 diagnostic procedure Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 210000003270 subclavian artery Anatomy 0.000 description 2
- 210000005166 vasculature Anatomy 0.000 description 2
- 241000405070 Percophidae Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 230000002965 anti-thrombogenic effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 238000013158 balloon valvuloplasty Methods 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 210000001715 carotid artery Anatomy 0.000 description 1
- 210000001168 carotid artery common Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000002001 electrophysiology Methods 0.000 description 1
- 230000007831 electrophysiology Effects 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000003557 neuropsychological effect Effects 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/013—Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/011—Instruments for their placement or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/06—Body-piercing guide needles or the like
- A61M25/0662—Guide tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22001—Angioplasty, e.g. PCTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2002/016—Filters implantable into blood vessels made from wire-like elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0067—Three-dimensional shapes conical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
- A61M2039/062—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof used with a catheter
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462050156P | 2014-09-14 | 2014-09-14 | |
| US62/050,156 | 2014-09-14 | ||
| US14/537,814 | 2014-11-10 | ||
| US14/537,814 US9877821B2 (en) | 2012-01-06 | 2014-11-10 | Introducer sheath with embolic protection |
| CN201580010030.3A CN106061434B (zh) | 2014-09-14 | 2015-09-14 | 具有栓塞保护的插管器鞘 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580010030.3A Division CN106061434B (zh) | 2014-09-14 | 2015-09-14 | 具有栓塞保护的插管器鞘 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108578013A CN108578013A (zh) | 2018-09-28 |
| CN108578013B true CN108578013B (zh) | 2020-06-16 |
Family
ID=55459709
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810228104.6A Active CN108578013B (zh) | 2014-09-14 | 2015-09-14 | 具有栓塞保护的插管器鞘 |
| CN201580010030.3A Active CN106061434B (zh) | 2014-09-14 | 2015-09-14 | 具有栓塞保护的插管器鞘 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580010030.3A Active CN106061434B (zh) | 2014-09-14 | 2015-09-14 | 具有栓塞保护的插管器鞘 |
Country Status (6)
| Country | Link |
|---|---|
| EP (4) | EP3193778B1 (enExample) |
| JP (1) | JP6612854B2 (enExample) |
| KR (1) | KR102452779B1 (enExample) |
| CN (2) | CN108578013B (enExample) |
| DE (1) | DE202015010042U1 (enExample) |
| WO (1) | WO2016040923A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9498604B2 (en) | 1997-11-12 | 2016-11-22 | Genesis Technologies Llc | Medical device and method |
| US10335577B2 (en) | 2010-05-19 | 2019-07-02 | Nfinium Vascular Technologies, Llc | Augmented delivery catheter and method |
| US9561094B2 (en) | 2010-07-23 | 2017-02-07 | Nfinium Vascular Technologies, Llc | Devices and methods for treating venous diseases |
| WO2013103979A1 (en) | 2012-01-06 | 2013-07-11 | Emboline, Inc. | Integrated embolic protection devices |
| US20150351775A1 (en) | 2014-06-04 | 2015-12-10 | Nfinium Vascular Technologies, Llc | Low radial force vascular device and method of occlusion |
| US10617509B2 (en) | 2015-12-29 | 2020-04-14 | Emboline, Inc. | Multi-access intraprocedural embolic protection device |
| EP3403615A1 (en) * | 2017-05-17 | 2018-11-21 | Aorticlab Sarl | Transcatheter valve prosthesis for blood vessel |
| JP7557475B2 (ja) | 2019-02-13 | 2024-09-27 | エンボライン, インコーポレイテッド | 統合された塞栓保護デバイスを伴うカテーテル |
| US11707351B2 (en) | 2019-08-19 | 2023-07-25 | Encompass Technologies, Inc. | Embolic protection and access system |
| WO2021048855A1 (en) * | 2019-09-11 | 2021-03-18 | Invatin Technologies Ltd. | Device and method for controlling the flow of embolic material |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5989281A (en) | 1995-11-07 | 1999-11-23 | Embol-X, Inc. | Cannula with associated filter and methods of use during cardiac surgery |
| US5814064A (en) | 1997-03-06 | 1998-09-29 | Scimed Life Systems, Inc. | Distal protection device |
| US5769819A (en) | 1997-04-24 | 1998-06-23 | Medtronic, Inc. | Catheter distal tip component |
| US5911734A (en) | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
| US6258120B1 (en) | 1997-12-23 | 2001-07-10 | Embol-X, Inc. | Implantable cerebral protection device and methods of use |
| US6371935B1 (en) | 1999-01-22 | 2002-04-16 | Cardeon Corporation | Aortic catheter with flow divider and methods for preventing cerebral embolization |
| US6361545B1 (en) | 1997-09-26 | 2002-03-26 | Cardeon Corporation | Perfusion filter catheter |
| US6254563B1 (en) | 1997-12-15 | 2001-07-03 | Cardeon Corporation | Perfusion shunt apparatus and method |
| WO1999030765A1 (en) | 1997-12-15 | 1999-06-24 | Cardeon Corporation | Perfusion shunt apparatus and method |
| US20030100940A1 (en) | 2001-11-23 | 2003-05-29 | Mindguard Ltd. | Implantable intraluminal protector device and method of using same for stabilizing atheromas |
| US20030176884A1 (en) | 2002-03-12 | 2003-09-18 | Marwane Berrada | Everted filter device |
| WO2004019817A1 (en) | 2002-08-27 | 2004-03-11 | Amir Belson | Embolic protection device |
| WO2004021922A2 (en) * | 2002-09-03 | 2004-03-18 | Morrill Richard J | Arterial embolic filter deployed from catheter |
| US20050137696A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Apparatus and methods for protecting against embolization during endovascular heart valve replacement |
| US20060287668A1 (en) * | 2005-06-16 | 2006-12-21 | Fawzi Natalie V | Apparatus and methods for intravascular embolic protection |
| AU2005334555A1 (en) * | 2005-07-19 | 2007-01-25 | Stout Medical Group L.P. | Embolic filtering method and apparatus |
| US20070073332A1 (en) | 2005-09-26 | 2007-03-29 | Medtronic Vascular, Inc. | Intraluminal filter having a cover sleeve |
| US9107734B2 (en) | 2006-11-29 | 2015-08-18 | Emboline, Inc. | Embolic protection device |
| RU2518457C2 (ru) * | 2008-09-04 | 2014-06-10 | Контего Аб | Устройство для временной защиты от эмболии и медицинская процедура для его введения |
| US20130096606A1 (en) * | 2011-10-17 | 2013-04-18 | William C. Bruchman | Embolic protection devices and related systems and methods |
| WO2013103979A1 (en) | 2012-01-06 | 2013-07-11 | Emboline, Inc. | Integrated embolic protection devices |
| US9089406B2 (en) * | 2012-02-03 | 2015-07-28 | The Cleveland Clinic Foundation | Embolic filter devices, systems, and methods for capturing emboli during medical procedures |
| CN102973332B (zh) * | 2012-11-23 | 2015-01-21 | 杭州启明医疗器械有限公司 | 血栓过滤器及其使用方法 |
| US9968433B2 (en) * | 2013-03-01 | 2018-05-15 | St. Jude Medical, Cardiology Division, Inc. | Embolic protection pass through tube |
-
2015
- 2015-09-14 JP JP2017513636A patent/JP6612854B2/ja active Active
- 2015-09-14 CN CN201810228104.6A patent/CN108578013B/zh active Active
- 2015-09-14 EP EP15840142.2A patent/EP3193778B1/en active Active
- 2015-09-14 KR KR1020177010028A patent/KR102452779B1/ko active Active
- 2015-09-14 EP EP23208896.3A patent/EP4338705A3/en active Pending
- 2015-09-14 CN CN201580010030.3A patent/CN106061434B/zh active Active
- 2015-09-14 EP EP24209721.0A patent/EP4491151A3/en active Pending
- 2015-09-14 EP EP20164920.9A patent/EP3705087B1/en active Active
- 2015-09-14 DE DE202015010042.2U patent/DE202015010042U1/de not_active Expired - Lifetime
- 2015-09-14 WO PCT/US2015/049908 patent/WO2016040923A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE202015010042U1 (de) | 2024-10-22 |
| JP6612854B2 (ja) | 2019-11-27 |
| WO2016040923A3 (en) | 2016-08-11 |
| CN106061434B (zh) | 2018-04-17 |
| EP4491151A2 (en) | 2025-01-15 |
| EP3193778B1 (en) | 2020-05-06 |
| KR102452779B1 (ko) | 2022-10-07 |
| EP4491151A3 (en) | 2025-04-23 |
| EP3193778A2 (en) | 2017-07-26 |
| EP4338705A3 (en) | 2024-06-19 |
| KR20170088332A (ko) | 2017-08-01 |
| CN108578013A (zh) | 2018-09-28 |
| EP3705087B1 (en) | 2023-12-27 |
| EP3705087A1 (en) | 2020-09-09 |
| JP2017528232A (ja) | 2017-09-28 |
| EP4338705A2 (en) | 2024-03-20 |
| WO2016040923A2 (en) | 2016-03-17 |
| EP3193778A4 (en) | 2018-04-18 |
| CN106061434A (zh) | 2016-10-26 |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |