CN108567964A - Tumour eliminating and analgesic cream - Google Patents

Tumour eliminating and analgesic cream Download PDF

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Publication number
CN108567964A
CN108567964A CN201810733555.5A CN201810733555A CN108567964A CN 108567964 A CN108567964 A CN 108567964A CN 201810733555 A CN201810733555 A CN 201810733555A CN 108567964 A CN108567964 A CN 108567964A
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parts
eliminating
tumour
alcohol
analgesic cream
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易小玲
马燕妮
廖文静
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Kunming Hospital of Traditional Chinese Medicine
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Kunming Hospital of Traditional Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
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    • A61K35/56Materials from animals other than mammals
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    • A61K35/648Myriapods, e.g. centipedes or millipedes
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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Abstract

The invention discloses Chinese medicine ointment technical fields, specific field is tumour eliminating and analgesic cream, smilax, edible tulip, monkshood are monarch drug in a prescription, smilax removing toxic substances, dehumidifying, monkshood dispelling wind and eliminating dampness, antalgic, edible tulip is clearing heat and detoxicating, reducing phlegm and resolving masses, three is used cooperatively, and can reach preferable dehumidifying, dissipating bind, the effect of analgesic and warming and activating meridian;Piper wallichii (Miq.) Hand.-Mazz. and caulis piperis futokadsurae drug effect are wind-damp dispelling, degrading the channel and stopping numbness pain, and there is centipede dispersing pathogen accumulation, effect of removing obstruction in channels to relieve pain, ground bettle and turmeric there is dissipating blood stasis with potent drugs, promoting qi circulation and relieving pain effect to collectively constitute as ministerial drug;Adjutant is collectively constituted with Chinese cassia tree, rhizoma zingiberis, cloves and asarum, and monarch-minister drug is assisted to further strengthen drug effect, and effect is warming spleen and stomach for dispelling cold, except cold, analgesic;Add and dissipate blood with borneol, dissipate fire, dissipate it is stagnant, it is sensible, after all the components are by wine tune, blood vessels can be made unimpeded, the effect of a surname leads medicine gesture, all medicines share in the present invention, and mutually collaboration reaches warming and activating meridian, dissolving stasis removing toxic substances, eliminating stagnation to stop pain.

Description

Tumour eliminating and analgesic cream
Technical field
The present invention relates to Chinese medicine ointment technical field, specific field is tumour eliminating and analgesic cream.
Background technology
Chinese medicine just had tumour before bimillennium certain understanding, just there is the record of " tumor " word in the inscriptions on bones or tortoise shells, other Seeing the titles such as " tongue bacterium, mistake is flourish, dysphagic, return stomach, mammary cancer, lung are long-pending and magic flower sore " in document is faced modern malignant tumour The description of bed performance, Chinese medicine are mostly healthy tendency virtual loss to the understanding of the tumor etiology interpretation of the cause, onset and process of an illness, and cult poison is invaded outside or interior life, causes the stagnation of the circulation of vital energy, blood The stasis of blood, phlegm are solidifying, damp and hot and heat toxin knot is poly- etc..《Ling Shu Miraculous Pivot or Divine Axis Ci Jiezhen is evil》Cloud:" empty heresy enters body also depth ... before disease Muscle, muscle, which must not bend, to be stretched, and perverse trend occupies therebetween without anti-, and hair is slipped in muscle.It is tied, gas returns it, defends gas and stays it, must not be anti-, and body fluid is long Stay, slipped combined into intestines, long person apply river bend and at, with hand by it is soft.It is tied, gas returns it, and body fluid stays it, it in perverse trend.Condensation Day is to be former times tumor, the heavily fortified point pressed with hand even to live in concentrated communities easily very ".《Ling Shu Miraculous Pivot or Divine Axis nine kinds of needles is discussed》Also cloud:" lump in the abdomen is phlegm and retained fluid in, on the right side For dyspepsia, in left category clot.Gas cannot make block at poly-, and block is tangible object, the dead blood of phlegm allusion quotation dyspepsia into ....”
The cause of disease stagnation of the circulation of vital energy that is formed for tumour, blood stasis, phlegm are solidifying, damp and hot and heat toxin knot is poly-, according to Chinese medicine " not general rule bitterly, no The effect of theory of Rong Ze pains ", proposes a kind of tumour eliminating and analgesic cream, reaches warming and activating meridian, and dissolving stasis is detoxified, eliminating stagnation to stop pain.
Invention content
The purpose of the present invention is to provide tumour eliminating and analgesic cream, to solve the problems mentioned in the above background technology.
To achieve the above object, the present invention provides the following technical solutions:Tumour eliminating and analgesic cream, raw material composition and corresponding weight Measuring number is:28~32 parts of Piper wallichii (Miq.) Hand.-Mazz., 28~32 parts of smilax, 18~22 parts of edible tulip, 8~12 parts of turmeric, monkshood 18~22 Part, 28~32 parts of caulis piperis futokadsurae, 8~12 parts of centipede, 18~22 parts of ground bettle, 8~12 parts of Chinese cassia tree, 8~12 parts of asarum, cloves 8~ 12 parts, 18~22 parts of rhizoma zingiberis, 3~7 parts of borneol.
Preferably, the centipede is Chinese medicine centipede.
Preferably, the ground bettle is Chinese medicine ground bettle.
Preferably, tumour eliminating and analgesic cream, preparation method are:
1) by Piper wallichii (Miq.) Hand.-Mazz., smilax, edible tulip, turmeric, monkshood, caulis piperis futokadsurae, centipede, ground bettle, Chinese cassia tree, asarum, cloves, Rhizoma zingiberis and borneol are added in medicinal herb grinder, are all smashed in powdery, spare;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) alcohol that the mass fraction prepared in the medicinal powder prepared in step 1) and step 2) is 30%, medicinal powder and alcohol are taken Mass ratio is 1:1, medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
Preferably, tumour eliminating and analgesic cream, application method are:Tumour eliminating and analgesic cream is applied to gauze part, is to carry with gauze Tumour eliminating and analgesic cream is externally applied to local pain position caused by tumour and various subcutaneous tumors by body, one time a day, 4 hours every time, is prohibited At skin ulceration.
The beneficial effects of the invention are as follows:Tumour eliminating and analgesic cream, smilax, edible tulip, monkshood are monarch drug in a prescription, i.e. smilax, mountain is kind Mushroom, monkshood are ingredient mostly important in the present invention, smilax removing toxic substances, dehumidifying, monkshood dispelling wind and eliminating dampness, antalgic, edible tulip Clearing heat and detoxicating, reducing phlegm and resolving masses, three is used cooperatively, and can reach preferable dehumidifying, dissipating bind, the effect of analgesic and warming and activating meridian;Stone Nanmu rattan and caulis piperis futokadsurae are ministerial drug, i.e., Piper wallichii (Miq.) Hand.-Mazz. and caulis piperis futokadsurae are the ingredient of the auxiliary monarch drug in a prescription reinforcement drug effect in the present invention, drug effect For, wind-damp dispelling, degrading the channel and stopping numbness pain, centipede have a dispersing pathogen accumulation, effect of removing obstruction in channels to relieve pain, ground bettle and turmeric have blood-breaking by The stasis of blood, promoting qi circulation and relieving pain effect, centipede, ground bettle and turmeric and Piper wallichii (Miq.) Hand.-Mazz. and caulis piperis futokadsurae collectively constitute as ministerial drug;Adjutant is with Chinese cassia tree, dry Ginger, cloves and asarum collectively constitute, and monarch-minister drug is assisted to further strengthen drug effect, and effect is warming spleen and stomach for dispelling cold, except cold, analgesic;This Blood is dissipated in invention plus with borneol, dissipates fire, it is scattered stagnant, it is sensible, after all the components are by wine tune, blood vessels can be made unimpeded, a surname leads medicine gesture, comprehensive It is upper described, the effect of all medicines share in the present invention, mutually collaboration reach warming and activating meridian, dissolving stasis removing toxic substances, eliminating stagnation to stop pain.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical scheme of the present invention is clearly and completely described, it is clear that institute The embodiment of description is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, Every other embodiment obtained by those of ordinary skill in the art without making creative efforts, belongs to this hair The range of bright protection.
Embodiment 1:
1) by Piper wallichii (Miq.) Hand.-Mazz. 28g, smilax 28g, edible tulip 18g, turmeric 8g, monkshood 18g, caulis piperis futokadsurae 28g, centipede 8g, soil Soft-shelled turtle worm 18g, Chinese cassia tree 8g, asarum 8g, cloves 8g, rhizoma zingiberis 18g and 3g borneol are added in medicinal herb grinder, are all smashed in powder Shape, it is spare;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) the alcohol 50ml that the mass fraction prepared in the medicinal powder 50g prepared in step 1) and step 2) is 30% is taken, it will Medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
Embodiment 2:
1) by Piper wallichii (Miq.) Hand.-Mazz. 29g, smilax 29g, edible tulip 19g, turmeric 9g, monkshood 19g, caulis piperis futokadsurae 29g, centipede 9g, soil Soft-shelled turtle worm 19g, Chinese cassia tree 9g, asarum 9g, cloves 9g, rhizoma zingiberis 19g and 4g borneol are added in medicinal herb grinder, are all smashed in powder Shape, it is spare;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) the alcohol 50ml that the mass fraction prepared in the medicinal powder 50g prepared in step 1) and step 2) is 30% is taken, it will Medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
Embodiment 3:
1) by Piper wallichii (Miq.) Hand.-Mazz. 30g, smilax 30g, edible tulip 20g, turmeric 10g, monkshood 20g, caulis piperis futokadsurae 30g, centipede 10g, Ground bettle 20g, Chinese cassia tree 10g, asarum 10g, cloves 10g, rhizoma zingiberis 20g and 5g borneol are added in medicinal herb grinder, are all smashed It is spare in powdery;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) the alcohol 50ml that the mass fraction prepared in the medicinal powder 50g prepared in step 1) and step 2) is 30% is taken, it will Medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
Embodiment 4:
1) by Piper wallichii (Miq.) Hand.-Mazz. 31g, smilax 31g, edible tulip 21g, turmeric 11g, monkshood 21g, caulis piperis futokadsurae 31g, centipede 11g, Ground bettle 21g, Chinese cassia tree 11g, asarum 11g, cloves 11g, rhizoma zingiberis 21g and 6g borneol are added in medicinal herb grinder, are all smashed It is spare in powdery;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) the alcohol 50ml that the mass fraction prepared in the medicinal powder 50g prepared in step 1) and step 2) is 30% is taken, it will Medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
Embodiment 5:
1) by Piper wallichii (Miq.) Hand.-Mazz. 32g, smilax 32g, edible tulip 22g, turmeric 22g, monkshood 22g, caulis piperis futokadsurae 32g, centipede 12g, Ground bettle 22g, Chinese cassia tree 12g, asarum 12g, cloves 12g, rhizoma zingiberis 22g and 7g borneol are added in medicinal herb grinder, are all smashed It is spare in powdery;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) the alcohol 50ml that the mass fraction prepared in the medicinal powder 50g prepared in step 1) and step 2) is 30% is taken, it will Medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
The tumour eliminating and analgesic cream for inviting 50 subjects that Examples 1 to 5 is used to prepare respectively, application method are:The tumor that will disappear is stopped Pain cream is applied to gauze part, and using gauze as carrier, tumour eliminating and analgesic cream is externally applied to local pain position caused by tumour and various Subcutaneous tumor 4 hours every time, disables at skin ulceration one time a day, as follows using feedback record result after 1 month:
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (5)

1. tumour eliminating and analgesic cream, it is characterised in that:Its raw material forms and corresponding parts by weight are:28~32 parts of Piper wallichii (Miq.) Hand.-Mazz., soil Fu 28~32 parts of Siberian cocklebur, 18~22 parts of edible tulip, 8~12 parts of turmeric, 18~22 parts of monkshood, 28~32 parts of caulis piperis futokadsurae, centipede 8~12 Part, 18~22 parts of ground bettle, 8~12 parts of Chinese cassia tree, 8~12 parts of asarum, 8~12 parts of cloves, 18~22 parts of rhizoma zingiberis, borneol 3~7 Part.
2. tumour eliminating and analgesic cream according to claim 1, it is characterised in that:The centipede is Chinese medicine centipede.
3. tumour eliminating and analgesic cream according to claim 1, it is characterised in that:The ground bettle is Chinese medicine ground bettle.
4. tumour eliminating and analgesic cream according to claim 1, it is characterised in that:Preparation method is:
1) by Piper wallichii (Miq.) Hand.-Mazz., smilax, edible tulip, turmeric, monkshood, caulis piperis futokadsurae, centipede, ground bettle, Chinese cassia tree, asarum, cloves, rhizoma zingiberis It is added in medicinal herb grinder, is all smashed in powdery with borneol, it is spare;
2) alcohol that mass fraction is 95% is diluted to the alcohol that mass fraction is 30% using purified water, it is spare;
3) alcohol that the mass fraction prepared in the medicinal powder prepared in step 1) and step 2) is 30%, medicinal powder and alcohol quality are taken Than being 1:1, medicinal powder is added in alcohol, is uniformly mixed, that is, is prepared into tumour eliminating and analgesic cream.
5. tumour eliminating and analgesic cream according to claim 1, it is characterised in that:Its application method is:Tumour eliminating and analgesic cream is smeared In gauze part, using gauze as carrier, tumour eliminating and analgesic cream is externally applied to local pain position caused by tumour and various subcutaneous tumors, One time a day, it every time 4 hours, disables at skin ulceration.
CN201810733555.5A 2018-07-06 2018-07-06 Tumour eliminating and analgesic cream Pending CN108567964A (en)

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消瘤止痛膏在骨转移癌疼痛治疗中的应用: "杨上望等", 《黑龙江中医药》 *

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Application publication date: 20180925