CN108562559A - Whole blood coagulation analytical equipment - Google Patents
Whole blood coagulation analytical equipment Download PDFInfo
- Publication number
- CN108562559A CN108562559A CN201810048021.9A CN201810048021A CN108562559A CN 108562559 A CN108562559 A CN 108562559A CN 201810048021 A CN201810048021 A CN 201810048021A CN 108562559 A CN108562559 A CN 108562559A
- Authority
- CN
- China
- Prior art keywords
- inner chamber
- chamber room
- detection cup
- whole blood
- blood coagulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000023555 blood coagulation Effects 0.000 title claims abstract description 29
- 238000001514 detection method Methods 0.000 claims abstract description 59
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 12
- 230000005693 optoelectronics Effects 0.000 claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 238000007689 inspection Methods 0.000 claims description 2
- 210000002381 plasma Anatomy 0.000 abstract description 4
- 238000004458 analytical method Methods 0.000 abstract description 3
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 238000002834 transmittance Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 241001597008 Nomeidae Species 0.000 description 3
- 230000010100 anticoagulation Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 238000007820 coagulation assay Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention provides a kind of whole blood coagulation analytical equipments, including：Detection cup carries disk, and the central shaft that detection cup carries disk is connect with driving device；Detection cup, detection cup are mounted in detection cup and carry in the outlet of disk, and detection cup includes：First inner chamber room and second inner chamber room, second inner chamber room is located at the obliquely downward of first inner chamber room, and it is connected to by an inclined-plane between first inner chamber room and second inner chamber room, the bottom face of first inner chamber room is that plane also is used to accept sample/reagent for accepting reagent/sample, the bottom face of second inner chamber room for plane；Light path system, light path system include at least light source emitter and opto-electronic receiver converter, and second inner chamber room is between light source emitter and opto-electronic receiver converter.Whole blood coagulation analytical equipment provided by the invention is simple and reasonable, realizes whole blood coagulation analysis, avoids and isolate the trouble that blood plasma is detected again, and is simple, convenient, improve detection efficiency.
Description
Technical field
The present invention relates to a kind of blood sample test equipment, more particularly to a kind of whole blood coagulation analytical equipment belongs to Medical Devices
Technical field.
Background technology
Quick blood clotting capability detection has highly important clinical meaning, is especially diagnosed to acute thrombus diseases
It is even more important.Currently, the assay method of blood clotting capability has very much, but the big blood plasma for mostly using separation is detected.It is existing
Whole blood test time of setting test or using manual operations, naked-eye observation, or by using vibration and feedback principle detect
Setting condition in blood.Error hand-manipulated is big, it is difficult to ensure inspection quality, and the principle detection vibrated and fed back exists at present
Domestic contrast is rare, equipment price is expensive, clinical application is restricted.
Therefore, how to provide it is a kind of it is quick, that accurate and cheap whole blood coagulation analytical equipment becomes industry is urgently to be resolved hurrily
Technical barrier.
Invention content
In order to solve the above technical problems, present invention aims at a kind of whole blood coagulation analytical equipment is provided, it is existing to overcome
The deficiency of technology.
In order to achieve the above objectives, technical scheme is as follows：
An embodiment of the present invention provides a kind of whole blood coagulation analytical equipments comprising：
Detection cup carries disk, and the central shaft that the detection cup carries disk is connect with driving device；
Detection cup, the detection cup group are mounted in the detection cup and carry in the outlet of disk, and the detection cup includes：
First inner chamber room and second inner chamber room, the second inner chamber room are located at the obliquely downward of the first inner chamber room, and described
It is connected to by an inclined-plane between one inner cavity chamber and second inner chamber room, the bottom face of the first inner chamber room is that plane is tried for accepting
The bottom face of agent/sample, the second inner chamber room is also that plane is used to accept sample/reagent；
Light path system, the light path system include at least light source emitter and opto-electronic receiver converter, the second inner chamber room position
Between the light source emitter and opto-electronic receiver converter.
As one of the preferred embodiment of the present invention, light source that the light source emitter is sent be infrared light, near infrared light and
Feux rouges.
One of preferred embodiment as the present invention, the edge of side where the second inner chamber room of the detection cup group is outward under
An inserted sheet is protruded out, the edge that the detection cup carries disk stretches out slot under outward, and the detection cup passes through the inserted sheet
Cooperation with the slot and realize the grafting that disk is carried with the detection cup.
One of preferred embodiment as the present invention, a lid is provided with above the first inner chamber room and second inner chamber room
Plate, offer on the cover board reagent/sample entrance port being located on the first inner chamber room and second inner chamber room and sample/
Reagent inlet.
It is further preferred that the cover board is downwardly extending guide channel by the edge of reagent/sample entrance port, and it is described
Guide channel is located at the top of the bottom face of the first inner chamber room.
It is convenient to hand-held handheld board it is further preferred that being fixedly provided with above the cover board.
One of preferred embodiment as the present invention, the detection cup are transparent cup body.
Compared with prior art, advantages of the present invention at least that：
Detection cup when in use, is first mounted in detection cup and carried on disk, will tried by whole blood coagulation analytical equipment provided by the invention
Agent and sample are added in respectively in the first inner chamber room and second inner chamber room of detection cup, which intermittently revolves
Turn multiple, under the action of the centrifugal force, so that reagent and sample is thrown out of and be uniformly mixed, then, light source emitter is sent out to mixed liquor
Infrared light, near infrared light and feux rouges are penetrated, light source is received by opto-electronic receiver converter so as to measure the light transmittance of blood sample, because
Light transmittance is directly proportional to blood clotting capability, thus can obtain blood clotting capability by light transmittance.It is provided by the invention complete
Coagulation assay apparatus structure advantages of simple realizes whole blood coagulation analysis, avoids and isolate the fiber crops that blood plasma is detected again
It is tired and simple, convenient, improve detection efficiency.
Description of the drawings
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, embodiment will be described below
In or the prior art needed in attached drawing be briefly described.
Fig. 1 is the structural schematic diagram of the whole blood coagulation analytical equipment disclosed in the embodiment of the present invention；
Fig. 2 is the vertical view of the whole blood coagulation analytical equipment disclosed in the embodiment of the present invention.
Specific implementation mode
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end
Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached
The embodiment of figure description is exemplary, it is intended to for explaining the present invention, and is not considered as limiting the invention.
In the description of the present invention, it is to be understood that, term "center", " longitudinal direction ", " transverse direction ", " length ", " width ",
" thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", "outside", " up time
The orientation or positional relationship of the instructions such as needle ", " counterclockwise " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of
The description present invention and simplified description, do not indicate or imply the indicated device or element must have a particular orientation, with spy
Fixed azimuth configuration and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for description purposes only, it is not understood to indicate or imply relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more this feature.In the description of the present invention, the meaning of " plurality " is two or more,
Unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc.
Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can be machine
Tool connects, and can also be electrical connection；It can be directly connected, can also can be indirectly connected through an intermediary two members
Connection inside part.For the ordinary skill in the art, above-mentioned term can be understood in this hair as the case may be
Concrete meaning in bright.
Shown in Fig. 1-2, an embodiment of the present invention provides a kind of whole blood coagulation analytical equipments comprising：
Detection cup carries disk 1, and the central shaft that detection cup carries disk 1 is connect with driving device；
Multiple detection cups 2（It is preferred that 4）, 2 townhouse of multiple detection cups is arranged to form detection cup group, and detection cup group is mounted in detection cup
In the outlet for carrying disk 1, detection cup 2 includes：
First inner chamber room 21 and second inner chamber room 22, second inner chamber room 22 are located at the obliquely downward of first inner chamber room 21, and in first
It is connected to by an inclined-plane K1 between chamber 21 and second inner chamber room 22, the bottom face K2 of first inner chamber room 21 is that plane is tried for accepting
Agent（Derivant）, the bottom face K3 of second inner chamber room 22 is also that plane is used to accept sample（Anticoagulation）；
Light path system, light path system include at least light source emitter 3 and opto-electronic receiver converter 4, and second inner chamber room 22 is located at light
Between source transmitter 3 and opto-electronic receiver converter 4.
As one of the preferred embodiment of the present invention, light source that light source emitter 3 is sent is infrared light, near infrared light and red
Light.
The edge of one of preferred embodiment as the present invention, the 22 place side of second inner chamber room of detection cup group is convex under outward
An inserted sheet 24 is stretched out, the edge that detection cup carries disk 1 stretches out slot 11 under outward, and detection cup 2 passes through inserted sheet 24 and slot
11 cooperation and realize with detection cup carry disk 1 grafting.
One of preferred embodiment as the present invention, the top of first inner chamber room 21 and second inner chamber room 22 is provided with a cover board
23, the reagent inlet 231 and sample entrance port being located on first inner chamber room 21 and second inner chamber room 22 are offered on cover board 23
232。
It is further preferred that cover board 23 is downwardly extending guide channel 233 by the edge of reagent inlet 231, and it is oriented to
Channel 233 is located at the top of the bottom face of first inner chamber room 21.
It is further preferred that the top of cover board 23, which is fixedly provided with, is convenient to hand-held handheld board 234.Handheld board 234 can be with
Staff is convenient to hold by detection cup 2 on detection cup carrying disk 1 or remove from detection cup carrying disk 1.
One of preferred embodiment as the present invention, detection cup 2 are transparent cup body, and detection cup can be observed by transparent cup body
The mixing situation of liquid in 2.
Whole blood coagulation analytical equipment provided by the invention carries on disk 1 in detection cup, derivant and anticoagulation is added respectively
In the first inner chamber room 21 and second inner chamber room 22 of detection cup 2, detection cup carries disk 1 and starts high speed rotation and drive detection cup
2 high speed rotations, under the influence of centrifugal force, derivant and anticoagulation are thrown out of in the inner space of entire detection cup 2（Including
Space other than first inner chamber room 21 and second inner chamber room 22 and first inner chamber room 21 and second inner chamber room 22）It is mixed,
Rapidly slow down velocity of rotation again, makes liquid reflux to second inner chamber room 22, it is intermittently repeated multiple times that liquid three-dimensional can be made to turn
It is dynamic to be mixed well with reaching liquid；
Finally constant speed rotates again, starts to carry out dynamic detection to reaction solution in cup：Light source emitter 3 emits infrared to mixed liquor
Light, near infrared light and feux rouges receive light source so as to measure the light transmittance of blood sample, because of light transmission by opto-electronic receiver converter 4
Degree is directly proportional to blood clotting capability, thus can obtain blood clotting capability by light transmittance.Whole blood provided by the invention is solidifying
Gu analytical equipment is simple and reasonable, whole blood coagulation analysis is realized, the trouble of separated plasma is avoided.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest range caused.
Claims (7)
1. a kind of whole blood coagulation analytical equipment, it is characterised in that including：
Detection cup carries disk, and the central shaft that the detection cup carries disk is connect with driving device；
Multiple detection cups, multiple detection cup townhouses are arranged to form detection cup group, and the detection cup group is mounted in the inspection
It surveys cup to carry in the outlet of disk, the detection cup includes：
First inner chamber room and second inner chamber room, the second inner chamber room are located at the obliquely downward of the first inner chamber room, and described
It is connected to by an inclined-plane between one inner cavity chamber and second inner chamber room, the bottom face of the first inner chamber room is that plane is tried for accepting
The bottom face of agent/sample, the second inner chamber room is also that plane is used to accept sample/reagent；
Light path system, the light path system include at least light source emitter and opto-electronic receiver converter, the second inner chamber room position
Between the light source emitter and opto-electronic receiver converter.
2. whole blood coagulation analytical equipment according to claim 1, it is characterised in that：The light source that the light source emitter is sent
For infrared light, near infrared light and feux rouges.
3. whole blood coagulation analytical equipment according to claim 1, it is characterised in that：The second inner chamber room of the detection cup group
The edge of place side protrudes out an inserted sheet under outward, and the edge that the detection cup carries disk stretches out slot under outward, institute
It states detection cup and realizes the grafting for carrying disk with the detection cup by the cooperation of the inserted sheet and the slot.
4. whole blood coagulation analytical equipment according to claim 1, it is characterised in that：The first inner chamber room and second inner chamber
It is provided with a cover board above room, the examination being located on the first inner chamber room and second inner chamber room is offered on the cover board
Agent/sample entrance port and sample/reagent inlet.
5. whole blood coagulation analytical equipment according to claim 4, it is characterised in that：The cover board is by reagent/sample entrance port
Edge be downwardly extending guide channel, and the guide channel is located at the top of the bottom face of the first inner chamber room.
6. whole blood coagulation analytical equipment according to claim 4, it is characterised in that：The side of being fixedly provided with above the cover board
Convenient for hand-held handheld board.
7. the whole blood coagulation analytical equipment according to any one of claim 1-6, it is characterised in that：The detection cup is
Bright cup body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810048021.9A CN108562559B (en) | 2018-01-18 | 2018-01-18 | Whole blood coagulation analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810048021.9A CN108562559B (en) | 2018-01-18 | 2018-01-18 | Whole blood coagulation analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108562559A true CN108562559A (en) | 2018-09-21 |
| CN108562559B CN108562559B (en) | 2024-05-07 |
Family
ID=63529842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810048021.9A Active CN108562559B (en) | 2018-01-18 | 2018-01-18 | Whole blood coagulation analyzer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108562559B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113049584A (en) * | 2021-03-18 | 2021-06-29 | 北京知新上智科技有限公司 | Blood coagulation analyzer and blood analysis system |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20030032812A (en) * | 2001-10-17 | 2003-04-26 | 장준근 | Microchip for measuring blood coagulation and apparatus for measuring blood coagulation using the same |
| CA2492486A1 (en) * | 2002-11-12 | 2004-05-27 | Inverness Medical Switzerland Gmbh | Photometric determination of coagulation time in undiluted whole blood |
| CN102331412A (en) * | 2011-10-08 | 2012-01-25 | 左峰 | Multifunctional analyzer device |
| CN105973811A (en) * | 2016-04-28 | 2016-09-28 | 江苏英诺华医疗技术有限公司 | Analyzer with blood analysis and biochemical analysis functions, and method thereof |
| CN207717622U (en) * | 2018-01-18 | 2018-08-10 | 中实医疗科技江苏有限公司 | Whole blood coagulation analytical equipment |
-
2018
- 2018-01-18 CN CN201810048021.9A patent/CN108562559B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20030032812A (en) * | 2001-10-17 | 2003-04-26 | 장준근 | Microchip for measuring blood coagulation and apparatus for measuring blood coagulation using the same |
| CA2492486A1 (en) * | 2002-11-12 | 2004-05-27 | Inverness Medical Switzerland Gmbh | Photometric determination of coagulation time in undiluted whole blood |
| CN102331412A (en) * | 2011-10-08 | 2012-01-25 | 左峰 | Multifunctional analyzer device |
| CN105973811A (en) * | 2016-04-28 | 2016-09-28 | 江苏英诺华医疗技术有限公司 | Analyzer with blood analysis and biochemical analysis functions, and method thereof |
| CN207717622U (en) * | 2018-01-18 | 2018-08-10 | 中实医疗科技江苏有限公司 | Whole blood coagulation analytical equipment |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113049584A (en) * | 2021-03-18 | 2021-06-29 | 北京知新上智科技有限公司 | Blood coagulation analyzer and blood analysis system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108562559B (en) | 2024-05-07 |
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