CN108553164A - A kind of vessel segment impedance detection device - Google Patents
A kind of vessel segment impedance detection device Download PDFInfo
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- CN108553164A CN108553164A CN201810241428.3A CN201810241428A CN108553164A CN 108553164 A CN108553164 A CN 108553164A CN 201810241428 A CN201810241428 A CN 201810241428A CN 108553164 A CN108553164 A CN 108553164A
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- impedance detection
- impedance
- conduit
- detection device
- distal end
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- 238000001514 detection method Methods 0.000 title claims abstract description 105
- 239000004020 conductor Substances 0.000 claims abstract description 14
- 230000005611 electricity Effects 0.000 claims description 3
- 230000002889 sympathetic effect Effects 0.000 description 14
- 210000005036 nerve Anatomy 0.000 description 12
- 238000002679 ablation Methods 0.000 description 11
- 210000004204 blood vessel Anatomy 0.000 description 6
- 238000005452 bending Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000036772 blood pressure Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 238000007674 radiofrequency ablation Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000000607 neurosecretory system Anatomy 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000008288 physiological mechanism Effects 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 208000015658 resistant hypertension Diseases 0.000 description 1
- 208000037905 systemic hypertension Diseases 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0538—Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6876—Blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00434—Neural system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
Abstract
The present invention relates to a kind of vessel segment impedance detection devices, including impedance detection circuit, impedance detection circuit includes two impedance detecting electrodes for being contacted with vessel outer wall, impedance detection circuit further includes the impedance detection components for being placed in human external when in use, impedance detection device further includes two impedance detection conduits, two impedance detecting electrodes are respectively arranged at the distal end of counterpart impedance detection conduit, and impedance detection circuit further includes the conduit inside conductor for connecting counterpart impedance detecting electrode and impedance detection components being laid in counterpart impedance detection conduit.The present invention provides a kind of vessel segment impedance detection devices that may be implemented to carry out vessel segment impedance detection.
Description
Technical field
The present invention relates to the Xue Guan Duan Pit detection devices in a kind of medical instruments field.
Background technology
Hypertension is cerebral apoplexy, coronary heart disease, heart failure, vascular diseases and the Major Risk Factors of chronic renal failure, is use up
Pathology, the physiological mechanism of pipe hypertension are complicated, but neuroendocrine system is to maintain the important mechanisms of blood pressure balance, sympathetic god
Warp be overexcited be considered as hypertension incidence basic link.A large amount of zoopery and clinical research also confirm that sympathetic god
Blood pressure through the influence to blood pressure, the excitement degree and patient that find sympathetic nerve is proportionate.Wherein sympathetic renal nerve system
System is the renal sympathetic outgoing and incoming nerve near the arteria renalis, for inducing and causing systemic hypertension to play important work
With, thus form the theory for blocking sympathetic renal nerve that can reduce blood pressure.
2009, Australian Henry Krum existed《Lancet》First use has been delivered on magazine percutaneously through conduit
Method melt in the arteria renalis vascular wall sympathetic nerve that is distributed using RF energy to treat resistant hypertension and obtain good
The human research of good effect, thereafter all over the world also again on the basis of carried out a series of research, obtain certain progress.
Chinese patent CN102551874B discloses a kind of renal artery radiofrequency ablation that can be directly used in arteria renalis endocardial ablation
Conduit, the conduit include control handle and bent catheter main body, are equipped in catheter main body and are set along catheter main body extending direction
The bracing wire set and shrapnel, the distal end of catheter main body are provided with the last straight section for being fixed with electrode.In use, by the distal end of catheter main body
It is sent in the arteria renalis, control handle controls bracing wire except human body, by controlling handle, can make the distal end of catheter main body
Bending is realized and is melted to the sympathetic nerve of the arteria renalis to make electrode touch the inner wall of the arteria renalis, and hand is controlled by rotation
Handle, thus it is possible to vary the ablation locations of electrode, final realize melt the sympathetic nerve of the arteria renalis, and catheter main body may be implemented in shrapnel
Distal end reset.Although existing this radio frequency ablation catheter can realize the ablation to arteria renalis sympathetic nerve, sympathetic
The ablation effect of nerve is not easy to judge, is the ablation effect that renal tissue is judged by ablation time and the experience of doctor in the past
Fruit is susceptible to and judges inaccurate problem.
Invention content
The purpose of the present invention is to provide a kind of vessel segment impedance detections that may be implemented to carry out vessel segment impedance detection
Device.
In order to solve the above technical problems, technical scheme is as follows：
A kind of vessel segment impedance detection device, including impedance detection circuit, impedance detection circuit include two for outside blood vessel
The impedance detecting electrode of wall contact, impedance detection circuit further includes the impedance detection section for being placed in human external when in use
Part, impedance detection device further include two impedance detection conduits, and two impedance detecting electrodes are respectively arranged at counterpart impedance detection
The distal end of conduit, impedance detection circuit further include being laid in counterpart impedance detection conduit to detect electricity for connecting counterpart impedance
The conduit inside conductor of pole and impedance detection components.
The impedance detection components include battery, voltmeter and ammeter.
The impedance detecting electrode is made of the ferrule for being fixed on impedance detection distal end of catheter, ferrule have for
The distal end and peripheral surface of the vessel outer wall contact.
Impedance detection device further includes control handle corresponding with each impedance detection conduit, it is each control handle respectively with it is right
The proximal end of impedance detection conduit is answered to be connected, the distal end of impedance detection conduit is adjustable curved segment, and impedance detecting electrode is set to adjustable
The end of curved segment, the bracing wire that shrapnel is both provided in each impedance detection conduit and is connected with the control handle.
The conductor part for being connected to the impedance detection components and controlling between handle is flexible circuit conductor.
Beneficial effects of the present invention are：In use, in the human body that the distal end of two impedance detection conduits is sent into, make two
Impedance detecting electrode is contacted with detected vessel segment respectively, is detected between two impedance detecting electrodes by impedance detection components
The impedance of vessel segment, because sympathetic nerve itself can transmit charge, after sympathetic nerve is destroyed, impedance can be affected, and lead to
The impedance detection to this section of blood vessel is crossed to judge ablation effect, judges to compare for traditional artificial micro-judgment by data,
Judging result is more accurate, objective.
Further, the distal end of impedance detection conduit is adjustable curved segment can pass through operation and control hand in practical operation
Handle, control handle adjustable curved segment is drawn by bracing wire, so that the distal end of impedance detection conduit bend, to change impedance detecting electrode and
The axially contact position of vessel outer wall, the blood vessel segment length between two such impedance detecting electrode change, not only can be with
It realizes the detection of multigroup impedance data, can also realize the impedance detection for different blood vessel length vessel segment.
Further, the conductor part for being connected to the impedance detection components and controlling between handle is flexible circuit conductor, soft to lead
For line without limitation on the rotation of control handle, the bending direction of impedance detection distal end of catheter can be changed by controlling handle by rotation,
The length that thus can further change vessel segment between two impedance detecting electrodes, obtains more testing results, fits
Answer wider array of detection range.
Description of the drawings
It is usage state diagram that Fig. 1, which is one embodiment of the present of invention,；
Fig. 2 is the detection principle diagram of the first occupation mode of the invention；
Fig. 3 is the detection principle diagram of second of occupation mode of the invention；
Fig. 4 is the detection principle diagram of the third occupation mode of the invention.
Specific implementation mode
A kind of implementation of vascular hindrance detection device is for example shown in Fig. 1 ~ 4：Including impedance detection circuit, impedance detection circuit
Include two impedance detecting electrodes 2 for being contacted with the outer wall of blood vessel 1, impedance detection circuit further includes for setting when in use
In the impedance detection components of human external, the present embodiment middle impedance detection part includes battery, voltmeter and ammeter.Impedance is examined
It further includes two impedance detection conduits 3 to survey device, and the distal end of impedance detection conduit 3 is adjustable curved segment 5, in impedance detection conduit
Proximal end is provided with control handle 6, and impedance detecting electrode 2 is by being fixed on the ferrule system of the adjustable curved segment end of impedance detection conduit
At the distal end in the present embodiment refers to one end far from performer, and ferrule has remote for being contacted with corresponding vessel outer wall
End 21 and peripheral surface 22 are held, the distal end of ferrule is ball head structure, that is to say, that the distal end spherical surface and and ball of ferrule
The peripheral surface of fan's link position can contact with vessel outer wall and carry out impedance detection.Along impedance detection in impedance detection conduit
Conduit extending direction is provided with bracing wire and shrapnel（It is not shown in figure）, the proximal end of bracing wire is connected with control handle, controls handle, draws
Mechanical connection relationship between line, shrapnel and impedance detection conduit belongs to the prior art, and arteria renalis radio frequency in the prior art disappears
Melt conduit and also use the structure, drawing is applied by bracing wire, the distal end bending of impedance detection conduit can be manipulated, specific connection is closed
This will not be detailed here for system.Conduit inside conductor, distal end and the impedance detecting electrode 2 of conduit inside conductor are provided in impedance detection conduit
It is connected, the proximal end of conduit inside conductor passes through after control handle 6 to be electrically connected with impedance detection components by conducting wire, in the present embodiment,
The conductor part for being connected to impedance detection components and controlling between handle is flexible circuit conductor 8.
In use, as shown in Figure 1, after carrying out arteria renalis ablation, two impedance detection conduits are deep into people through sheath 4
On the outside of the arteria renalis of body, the ferrule of impedance detecting electrode is contacted with detected vessel outer wall, can detect two impedance inspections
The impedance for surveying the vessel segment between electrode examines vessel segment impedance if after impedance detection conduit is directly stretched out by sheath
If survey, the vessel segment distance between two impedance detecting electrodes has as shown in Fig. 2, needing multigroup impedance data sometimes
When ablation areas the inconsistent vessel segment impedance detection device that can all result in the need for of length can detect the blood of different length
The impedance of pipeline section, when carrying out greatly apart from vessel segment impedance detection as shown in figure 3, two impedances can be made with operating control handle
The adjustable curved segment of detection conduit is rolled over towards opposite lateral bending, can greatly increase the vessel segment between two impedance detecting electrodes in this way
Length can also only there are one the adjustable curved segments of impedance detection conduit to bend certainly according to actual detection demand；Carry out
It is as shown in Figure 4 when small distance vessel segment impedance detection：Control handle can be rotated, the adjustable curved segment of two impedance detection conduits is made
Towards opposite bending, the length of vessel segment between two impedance detecting electrodes can be reduced, therefore by adjustable curved segment
It adjusts to change the length of tested vessel segment, to obtain multigroup impedance data, carry out impedance for different length ablation areas
Detection.The impedance detection purpose of certain vessel segment may not be the ablation effect for judging sympathetic nerve, face actual
On bed, there is the impedance value for being many times required for using vessel segment, the present invention is not only limited to be used for arteria renalis blood vessel at this time.
In other embodiments of the invention, battery can not also be set, and impedance detection components can be supplied by alternating current at this time
Electricity, impedance detection components include the transformer for carrying out transformation to alternating current；Impedance detection components can also be the resistance of integrated form
Anti- tester, for example, Zurich Instruments Chinese companies of Switzerland sale high-precision LCR impedance analyzers.
Claims (5)
1. a kind of vessel segment impedance detection device, it is characterised in that：Including impedance detection circuit, impedance detection circuit includes two
Impedance detecting electrode for being contacted with vessel outer wall, impedance detection circuit further include for being placed in human external when in use
Impedance detection components, impedance detection device further include two impedance detection conduits, and two impedance detecting electrodes are respectively arranged at pair
It further includes being laid in counterpart impedance detection conduit to be used for electrical connection pair to answer the distal end of impedance detection conduit, impedance detection circuit
Answer the conduit inside conductor of impedance detecting electrode and impedance detection components.
2. impedance detection device according to claim 1, it is characterised in that：The impedance detection components include battery, electricity
Press table and ammeter.
3. vessel segment impedance detection device according to claim 1, it is characterised in that：The impedance detecting electrode is by fixing
It is made in the ferrule of impedance detection distal end of catheter, ferrule has distal end for contact with the vessel outer wall and outside
Circumferential surface.
4. the impedance detection device according to claim 1 ~ 3 any one, it is characterised in that：Impedance detection device further includes
Control handle corresponding with each impedance detection conduit, each handle that controls are connected with the proximal end of counterpart impedance detection conduit respectively,
The distal end of impedance detection conduit is adjustable curved segment, and impedance detecting electrode is set to the end of adjustable curved segment, is led in each impedance detection
The bracing wire for being both provided with shrapnel in pipe and being connected with the control handle.
5. impedance detection device according to claim 4, it is characterised in that：It is connected to the impedance detection components and control
Conductor part between handle is flexible circuit conductor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810241428.3A CN108553164B (en) | 2018-03-22 | 2018-03-22 | Vascular segment impedance detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810241428.3A CN108553164B (en) | 2018-03-22 | 2018-03-22 | Vascular segment impedance detection device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108553164A true CN108553164A (en) | 2018-09-21 |
| CN108553164B CN108553164B (en) | 2023-12-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810241428.3A Active CN108553164B (en) | 2018-03-22 | 2018-03-22 | Vascular segment impedance detection device |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102551874A (en) * | 2011-10-20 | 2012-07-11 | 上海微创电生理医疗科技有限公司 | Renal artery radiofrequency ablation catheter |
| CN102961181A (en) * | 2011-09-01 | 2013-03-13 | 韦伯斯特生物官能(以色列)有限公司 | Catheter adapted for direct tissue contact |
| CN105212932A (en) * | 2015-11-06 | 2016-01-06 | 南开大学 | A kind of intelligent organizational separating operation apparatus that can detect bio-electrical impedance |
| US20160095535A1 (en) * | 2014-10-01 | 2016-04-07 | Medtronic Ardian Luxembourg S.a.r.I. | Systems and Methods for Evaluating Neuromodulation Therapy Via Hemodynamic Responses |
| US20160199126A1 (en) * | 2013-10-04 | 2016-07-14 | Japan Electel Inc. | Balloon catheter ablation system |
| CN107456273A (en) * | 2016-06-02 | 2017-12-12 | 韦伯斯特生物官能(以色列)有限公司 | For the foley's tube for detecting occlusion and the related method based on impedance |
| CN208492302U (en) * | 2018-03-22 | 2019-02-15 | 高传玉 | Vessel segment impedance detection device |
-
2018
- 2018-03-22 CN CN201810241428.3A patent/CN108553164B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961181A (en) * | 2011-09-01 | 2013-03-13 | 韦伯斯特生物官能(以色列)有限公司 | Catheter adapted for direct tissue contact |
| CN102551874A (en) * | 2011-10-20 | 2012-07-11 | 上海微创电生理医疗科技有限公司 | Renal artery radiofrequency ablation catheter |
| US20160199126A1 (en) * | 2013-10-04 | 2016-07-14 | Japan Electel Inc. | Balloon catheter ablation system |
| US20160095535A1 (en) * | 2014-10-01 | 2016-04-07 | Medtronic Ardian Luxembourg S.a.r.I. | Systems and Methods for Evaluating Neuromodulation Therapy Via Hemodynamic Responses |
| CN105212932A (en) * | 2015-11-06 | 2016-01-06 | 南开大学 | A kind of intelligent organizational separating operation apparatus that can detect bio-electrical impedance |
| CN107456273A (en) * | 2016-06-02 | 2017-12-12 | 韦伯斯特生物官能(以色列)有限公司 | For the foley's tube for detecting occlusion and the related method based on impedance |
| CN208492302U (en) * | 2018-03-22 | 2019-02-15 | 高传玉 | Vessel segment impedance detection device |
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| Publication number | Publication date |
|---|---|
| CN108553164B (en) | 2023-12-12 |
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