CN108489961A - A kind of rotating disc type drug mixture homogeneity detection device - Google Patents

A kind of rotating disc type drug mixture homogeneity detection device Download PDF

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Publication number
CN108489961A
CN108489961A CN201810316811.0A CN201810316811A CN108489961A CN 108489961 A CN108489961 A CN 108489961A CN 201810316811 A CN201810316811 A CN 201810316811A CN 108489961 A CN108489961 A CN 108489961A
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CN
China
Prior art keywords
detection
support base
turntable
monitor station
rotating disc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201810316811.0A
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Chinese (zh)
Inventor
郑钢
于浩
刘耀光
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SUZHOU YOUPUDE PRECISION INSTRUMENT Co Ltd
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SUZHOU YOUPUDE PRECISION INSTRUMENT Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by SUZHOU YOUPUDE PRECISION INSTRUMENT Co Ltd filed Critical SUZHOU YOUPUDE PRECISION INSTRUMENT Co Ltd
Priority to CN201810316811.0A priority Critical patent/CN108489961A/en
Publication of CN108489961A publication Critical patent/CN108489961A/en
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering

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  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The invention discloses a kind of rotating disc type drug mixture homogeneity detection devices,Including detecting babinet,Raman spectrometer,Electric expansion component,Support base,Turntable,Monitor station,Display screen and control device,The Raman spectrometer is fixedly mounted on the inner upper end of the detection babinet,The electric expansion component is mounted on the interior lower end of the detection babinet,The support base is fixed on the pars contractilis of the electric expansion component,The turntable is rotatably installed in by motor on the support base,The monitor station is rounded and on the turntable,The monitor station is equipped with several pallets placed for drug container,The pallet is located at the lower section of the Raman spectrometer,The pallet is mounted on by electric up-down cylinder on the monitor station,The display screen and control device are fixedly mounted on the front outer wall of the detection babinet,The device can accelerate detection speed,Improve detection efficiency,Ensure detection accuracy.

Description

A kind of rotating disc type drug mixture homogeneity detection device
Technical field
The present invention relates to a kind of drug test device more particularly to a kind of rotating disc type drug mixture homogeneity detection devices.
Background technology
Drug batch mixing uniformity quality directly influences the drug effect of finished medicines, at this stage, the detection one of drug batch mixing mixing As way be to be shut down at the time of thinking that batch mixing is uniform, then in mixing tank material different parts sampling carry out laboratory Assay thinks that batch mixing reaches uniform if the content value of wherein certain ingredient is consistent, but due to the way Poor in timeliness, it is time-consuming, laborious, production efficiency is reduced, the uniformity of last batch mixing can not be completely secured.
Invention content
In order to solve the above technical problems, the object of the present invention is to provide one kind capable of accelerating detection speed, detection effect is improved Rate ensures the rotating disc type drug mixture homogeneity detection device of detection accuracy.
A kind of rotating disc type drug mixture homogeneity detection device proposed by the present invention, including detection babinet, Raman spectrometer, Electric expansion component, support base, turntable, monitor station, display screen and control device, the Raman spectrometer are fixedly mounted on described The inner upper end of babinet is detected, the electric expansion component is mounted on the interior lower end of the detection babinet, and the support base is solid It is scheduled on the pars contractilis of the electric expansion component, the turntable is rotatably installed in by motor on the support base, the detection Platform is rounded and on the turntable, and the monitor station is equipped with several pallets placed for drug container, the pallet Positioned at the lower section of the Raman spectrometer, the pallet is mounted on by electric up-down cylinder on the monitor station, the display Screen and control device are fixedly mounted on the front outer wall of the detection babinet, and the front of the detection babinet is equipped with electronic Door, the display screen are communicated to connect with the Raman spectrometer, the electric expansion component, motor, electric up-down cylinder and electricity Control device communication connection described in dynamic Men Junyu.
Further, the pallet is six and is even spaced around setting on the monitor station.
Further, the electric expansion component is made of two electric telescopic rod spacing side by side, the electric expansion group Part is in horizontal front and back setting.
Further, the support base is inverted u-shaped, and two side bottom of inverted U of the support base is separately fixed at two electricity On the pars contractilis of dynamic telescopic rod, the motor is mounted on the support base bosom, and the turntable is mounted on the support base Upper surface on, turntable fixation is set in the shaft of the motor.
Further, the electrically operated gate is mounted on the front of the detection babinet.
Further, the control device includes PLC circuit plate and several manipulation buttons.
According to the above aspect of the present invention, the present invention has at least the following advantages:The pallet energy being arranged by uniform intervals on monitor station It is enough once to place multiple drug samples for needing to detect, correspondence drug sample to be detected can be rotated by the rotation of turntable To the underface of Raman spectrometer, pallet is lifted by electric up-down cylinder, to which drug sample is risen to Raman spectrum The test position of instrument acquires the characteristic spectrum data of drug ingedient to be detected by raman laser technology, and it is mixed that drug may be implemented Expect uniformity detection, without modeling, quickly, efficiently.It being combined by Raman spectrum data and spectrogram, testing result is more intuitive, It is very clear to the batch mixing uniformity situation in mixing process, it grasps in real time, improves the efficiency and accuracy rate of batch mixing, accuracy rate Up to 95% or more, accuracy of detection can be realized within 0.01.The mixing that the device can disposably detect multiple drug samples is equal Evenness sets the detection time of the rotation distance and Raman spectrometer in turntable each stage by control device, when having detected one After medicine material in a pallet, next drug sample is turned to the test position of Raman spectrometer by control device automatically, To carry out the detection of Non-intermittent, detection speed is improved, and the detection that back rotation monitor station is repeated can be carried out, it is ensured that inspection The accuracy for surveying result, when staff suspects the mixture homogeneity testing result of the drug sample in certain certain pallet When, can the drug sample directly be turned to by test position by control device again and be detected again, easy to operate, side Just, detection speed is fast, and detection efficiency is high, ensures detection accuracy.
Above description is only the general introduction of technical solution of the present invention, in order to better understand the technical means of the present invention, And can be implemented in accordance with the contents of the specification, below with presently preferred embodiments of the present invention and after coordinating attached drawing to be described in detail such as.
Description of the drawings
Fig. 1 is the structural schematic diagram of rotating disc type drug mixture homogeneity detection device of the present invention.
Specific implementation mode
With reference to the accompanying drawings and examples, the specific implementation mode of the present invention is described in further detail.Implement below Example is not limited to the scope of the present invention for illustrating the present invention.
Embodiment:A kind of rotating disc type drug mixture homogeneity detection device, including detection babinet 1, Raman spectrometer 2, electricity Dynamic telescopic component 3, support base 4, turntable 5, monitor station 6, display screen 7 and control device 8, the Raman spectrometer are fixedly mounted on The inner upper end of the detection babinet, the electric expansion component are mounted on the interior lower end of the detection babinet, the support Seat is fixed on the pars contractilis of the electric expansion component, and the turntable is rotatably installed in by motor 9 on the support base, described Monitor station is rounded and on the turntable, and the monitor station is equipped with several pallets 10 placed for drug container, institute The lower section that pallet is located at the Raman spectrometer is stated, the pallet is mounted on by electric up-down cylinder 11 on the monitor station, The display screen and control device are fixedly mounted on the front outer wall of the detection babinet, and the front of the detection babinet is set There are electrically operated gate 12, the display screen to be communicated to connect with the Raman spectrometer, the electric expansion component, motor, electric up-down Cylinder and electrically operated gate are communicated to connect with the control device.
The pallet is six and is even spaced around setting on the monitor station.
The electric expansion component is made of two electric telescopic rod spacing side by side, before the electric expansion component is in level After be arranged.
The support base is inverted u-shaped, and two side bottom of inverted U of the support base is separately fixed at two electric telescopic rods On pars contractilis, the motor is mounted on the support base bosom, and the turntable is mounted on the upper surface of the support base, The turntable fixation is set in the shaft of the motor.
The electrically operated gate is mounted on the front of the detection babinet.
The control device includes PLC circuit plate and several manipulation buttons.
The rotating disc type drug mixture homogeneity detection device can be primary by the pallet that uniform intervals on monitor station are arranged Multiple drug samples for needing to detect are placed, correspondence drug sample to be detected can be turned to by Raman by the rotation of turntable Pallet is lifted by electric up-down cylinder in the underface of spectrometer, to which drug sample to be risen to the inspection of Raman spectrometer Location is set, and the characteristic spectrum data of drug ingedient to be detected are acquired by raman laser technology, it is uniform that drug batch mixing may be implemented Degree detection, without modeling, quickly, efficiently.It is combined by Raman spectrum data and spectrogram, testing result is more intuitive, to batch mixing Batch mixing uniformity situation in the process is very clear, grasps in real time, improves the efficiency and accuracy rate of batch mixing, accuracy rate is up to 95% or more, accuracy of detection can be realized within 0.01.
The device can disposably detect the mixture homogeneity of multiple drug samples, and it is each to set turntable by control device The rotation distance in stage and the detection time of Raman spectrometer, after having detected the medicine material in a pallet, control device The test position that next drug sample is turned to Raman spectrometer automatically improves detection to carry out the detection of Non-intermittent Speed, and the detection that back rotation monitor station is repeated can be carried out, it is ensured that the accuracy of testing result, when staff is to certain It, can be directly by control device by the medicine when mixture homogeneity testing result of drug sample in certain pallet is suspected Object sample turns to test position and is detected again again, simple, convenient, and detection speed is fast, and detection efficiency is high, ensures Detection accuracy.
The above is only a preferred embodiment of the present invention, it is not intended to restrict the invention, it is noted that for this skill For the those of ordinary skill in art field, without departing from the technical principles of the invention, can also make it is several improvement and Modification, these improvements and modifications also should be regarded as protection scope of the present invention.

Claims (6)

1. a kind of rotating disc type drug mixture homogeneity detection device, it is characterised in that:Including detection babinet, Raman spectrometer, electricity Dynamic telescopic component, support base, turntable, monitor station, display screen and control device, the Raman spectrometer are fixedly mounted on the inspection The inner upper end of measuring tank body, the electric expansion component are mounted on the interior lower end of the detection babinet, and the support base is fixed In the pars contractilis of the electric expansion component, the turntable is rotatably installed in by motor on the support base, the monitor station Rounded and on the turntable, the monitor station is equipped with several pallets placed for drug container, the pallet position In the lower section of the Raman spectrometer, the pallet is mounted on by electric up-down cylinder on the monitor station, the display screen It being fixedly mounted on control device on the front outer wall of the detection babinet, the front of the detection babinet is equipped with electrically operated gate, The display screen is communicated to connect with the Raman spectrometer, the electric expansion component, motor, electric up-down cylinder and electrically operated gate Communicated to connect with the control device.
2. a kind of rotating disc type drug mixture homogeneity detection device according to claim 1, it is characterised in that:The pallet For six and setting is even spaced around on the monitor station.
3. a kind of rotating disc type drug mixture homogeneity detection device according to claim 2, it is characterised in that:It is described electronic Telescopic component is made of two electric telescopic rod spacing side by side, and the electric expansion component is in horizontal front and back setting.
4. a kind of rotating disc type drug mixture homogeneity detection device according to claim 3, it is characterised in that:The support Seat is inverted u-shaped, and two side bottom of inverted U of the support base is separately fixed on the pars contractilis of two electric telescopic rods, the electricity Machine is mounted on the support base bosom, and the turntable is mounted on the upper surface of the support base, the turntable fixing sleeve It is located in the shaft of the motor.
5. a kind of rotating disc type drug mixture homogeneity detection device according to claim 4, it is characterised in that:It is described electronic Door is mounted on the front of the detection babinet.
6. a kind of rotating disc type drug mixture homogeneity detection device according to claim 5, it is characterised in that:The manipulation Device includes PLC circuit plate and several manipulation buttons.
CN201810316811.0A 2018-04-10 2018-04-10 A kind of rotating disc type drug mixture homogeneity detection device Withdrawn CN108489961A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810316811.0A CN108489961A (en) 2018-04-10 2018-04-10 A kind of rotating disc type drug mixture homogeneity detection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810316811.0A CN108489961A (en) 2018-04-10 2018-04-10 A kind of rotating disc type drug mixture homogeneity detection device

Publications (1)

Publication Number Publication Date
CN108489961A true CN108489961A (en) 2018-09-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810316811.0A Withdrawn CN108489961A (en) 2018-04-10 2018-04-10 A kind of rotating disc type drug mixture homogeneity detection device

Country Status (1)

Country Link
CN (1) CN108489961A (en)

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Application publication date: 20180904

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